LOCUS       NZ_CP025957            24549 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Paenibacillus polymyxa strain HY96-2 chromosome, complete genome.
ACCESSION   NZ_CP025957
VERSION     NZ_CP025957.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Complete genome sequence of Paenibacillus polymyxa HY96-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2018) East China University of Science and
            Technology, Laboratory of Marine Biochemical Engineering, Meilong
            Road No. 130, Shanghai 200237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Expected Final Version            :: no
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002893885.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:33:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,010
            CDSs (total)                      :: 4,854
            Genes (coding)                    :: 4,742
            CDSs (with protein)               :: 4,742
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 76 of 112
            Pseudo Genes (incomplete)         :: 39 of 112
            Pseudo Genes (internal stop)      :: 14 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:53:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5081332
            Orig. end                         :: 5105881
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025957.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="19"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14549](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14549)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(467..2071)
                     /locus_tag="C1A50_RS25875"
                     /old_locus_tag="C1A50_4709"
     CDS             complement(467..2071)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C1A50_RS25875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C1A50_4709"
                     /product="hypothetical protein"
                     /protein_id="WP_260846343.1"
                     /transl_table=11
                     /translation="MNMNRSIAFVIHNLVLYETIKPLIEECEKKQIVCDIYVPHIEEDD
                     WGDMSLDTYHYLKNNGINVTLTSAVPDKAYKIAFYPYLPYYLEVKSDYKFRYQYGMAKP
                     NWNLDTWSRNFDFIFCNGLYDSSVLAAYTQTEIVGMIKYAKFQRMKRETDKYNLLYLPT
                     YGNESSIELVMNHIEEISDTFNMKVKLHHGTSFLEHDRVSLVKSHVPEVLDHKASLVHL
                     IEEADVILSDGSGAIFDALFTDTPIVIFQHPQTESFEGILPLEEQIVQQNIVPFVSDND
                     NIKQTLLNAILDEQLIQQRRKFTLEMFPVKGRETIDKCMDVINRFLQDDVDQAYRAGHT
                     RLKNEFNELQTHNQNQSQEIEQQKQRIAEHTDQINTLIQTRDHQENVINSMSADIRSLS
                     EKKDELEQQYAQLTQDYNDEKNNLDILNHQYRQLFGQYNELNTQFSELQEYNGRLSTEL
                     HNIYNSKRWKMANKLKHILHKSKMIYVLKGYRVWKNYGTTILLKRLNLKCRISLNGLTQ
                     GIILLICAKMKETTISY"
     gene            complement(2105..2518)
                     /locus_tag="C1A50_RS22090"
                     /old_locus_tag="C1A50_4710"
     CDS             complement(2105..2518)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822980.1"
                     /locus_tag="C1A50_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4710"
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="WP_016822980.1"
                     /sec_met_domain="CTP_transf_like (E-value: 6.5e-21,
                     bitscore: 73.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIGYTSGVFDLFHIGHLNLLRNAKSLCDKLIVGVTTDELVSYKY
                     KKAVIPFEERIEIVRNIKFVDTVIPQDSMDKFEVWQKLKYDVMFVGDDWFQNERWDQYE
                     LQFKEVGVKIIYFPYTKSTSSTLLNETLLKLRK"
     gene            complement(2515..4053)
                     /gene="asnB"
                     /locus_tag="C1A50_RS22095"
                     /old_locus_tag="C1A50_4711"
     CDS             complement(2515..4053)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312206.1"
                     /locus_tag="C1A50_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4711"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_038978184.1"
                     /sec_met_domain="GATase_7 (E-value: 5.4e-39, bitscore:
                     131.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.5e-58, bitscore:
                     195.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGILFSNVAINKEAFLNSLNIMKHRGPTAPLCVYQHENFMLGHN
                     RLSILDLDQRSDQPFFSDDGRYVIIFNGEIYNYKELASTYSIQMRTNSDTELLLKLYIQ
                     YGPQMLNWLNGMFSFIVLDVQHKSFFAARDRMGVKPLYYNKNGEEFIFSSEIAPLLPLV
                     HNVSLDQAAVRQYKKMRCFFNNRTVYNEIKEFPPGYYYENGEFIKYWELDYSEKEPPSD
                     EELEFLIRSAVEYRKIADVEIGSYLSGGLDSTIITALAGVEHTWTVGFEDYNEFEWSEI
                     AATRYNTIHHPILFDPDRFLSLARELVIVKKEPLSVPNEVLLYHMTQQASAKNTVILSG
                     EGADELFFGYDRIFRWASSTTDFDIRAFSDLYTYGSEDDLEIVEDALAPFMKLKSPQKI
                     VAAFFQQAHLRGLLKRLDSASMLNSVEARSPFLDYRLIERLAGVDAQYKMKDGVVKAPL
                     KRIFKDIIPAEIVNRKKVGFPVQLERVLSSEKIEGKTTFDKWFNFNLNTLGEIL"
     gene            complement(4067..5374)
                     /locus_tag="C1A50_RS22100"
                     /old_locus_tag="C1A50_4712"
     CDS             complement(4067..5374)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427437.1"
                     /locus_tag="C1A50_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4712"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_017427437.1"
                     /transl_table=11
                     /translation="MTQTESVAVEVNNVTKIYKIYDNPNERLKEAIHPFKKKYHSDFKA
                     ISDLSFSIKKGQAIGIIGKNGSGKSTLLKMITGVITPTHGSIKVNGKVAALLELGAGFN
                     PDLTGMENIYLNGTLMGYSKAEMDEKVEDITSFADIGDFINQPVKMYSSGMFARLAFAV
                     AINVDPDILIVDEALSVGDIYFQAKCITKMKELSKKSTVLFVSHSMDTIKSFCDTALLI
                     DKGHMVEIGPVKRVAQIYENIINQEIADMKRVQSLDTFVNSETDKKSTLLLLEEDPAFA
                     KRANEFRSGTGDARFIRADLLVNGEVVNQVPFGEMVTLRLLAQYYKDIDSEGTIGYMVR
                     NHTGVDVFGMNIYNKAKLVPKMQAGGILEVNFNFRNLLSESGKYTISIGLKPKPFEPLY
                     LDSVSIAAVFEVPKPENNYVPGLIFVDNTIDLQVIN"
     gene            complement(5385..6173)
                     /locus_tag="C1A50_RS22105"
                     /old_locus_tag="C1A50_4713"
     CDS             complement(5385..6173)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312208.1"
                     /locus_tag="C1A50_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4713"
                     /product="ABC transporter permease"
                     /protein_id="WP_026065453.1"
                     /transl_table=11
                     /translation="MNLTQNFSKNLKLLWELSKKDIQSRYLGSFMGVLWAFIHPMVSIL
                     VYWVVFQVGFKNVPIGDTPFILWLLTGMVPWLFFSESLSTATNSIIENNYLVKKIVFRV
                     GLLPMVKILAALFVHVFFIIVLFIMFKIYNVEFTMYNIQILYYLLATILLSLSISYITA
                     TLVVFVKDVGQIVGVFIQLFFWLTPIFWNLNIVEDKYQFFFKLNPVFYIVEGYRDTFIN
                     HKWFWEHPSMTIYFWAIVIIAGTIGIKIFKKMKSHFADVL"
     gene            6324..8774
                     /locus_tag="C1A50_RS22110"
                     /old_locus_tag="C1A50_4714"
     CDS             6324..8774
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822976.1"
                     /locus_tag="C1A50_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4714"
                     /product="O-antigen ligase family protein"
                     /protein_id="WP_016822976.1"
                     /sec_met_domain="Wzy_C (E-value: 4.6e-16, bitscore: 57.4,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPVYGKQAKTSTRDDKRPAMFWVLIVGMILFLAWAPFQAALFN
                     GQMLDFEKPLYWALIISTILLILGIVTYYKNFKLEDQRDWLAVLVILLPLTFVLSLISA
                     ASHYLAMNMVVVQCIYASFFIITLYALRDRLSNQIIQTAIMTVAYIIIGFGLINWFGQW
                     VLAGRLVDWFSTMVSGNRYVDAIKIDTNGPRLTSVFQYANTYAAFLMAFLFAAIFCLMK
                     SKTWYGKATHAFMLVPILVSLFLTLSRGGLIMLPVVFVLLLLFFKPARQILWLLHCAIA
                     GVVSLAILSPITNWGLQLNQTYNGAVAAKGWGLLLGTSLVTAVVLWLIQTSLGSRLEKR
                     MHGLASRKLSNLWLPVGSVVVIGVVAFLLIGTGLRTFLPANVETRLENINFQQHSVLER
                     ITFYRDASKLIADYPLIGAGGGGWATLYGKYQDYGYTSAQAHNFFMQYLVEAGILGFII
                     FMAFILYIFYKYIKGYIKSDEEKRDSHFLYLILAMSILLHSLLDFNMSYVFMGILVFIG
                     LGGMAAAMDAQPVKRLAMKPEGFRPIYSIVICVLSIVLLFVGLRFAQASNAAWEAKALE
                     SSNSFEQRQAAYNKDLNLRPTHIDSIVGLSSMYYQVYKQTKREEFYTGGMTIVDLGLQA
                     EPYNRNMLFIKMRLEQAKGNNDKAFAILENNRANFTWDLDWYNLLITQAFEFGNKARLA
                     KDSAKEQKYFQAGLAAYQQVLDGVAHLKTIPPEIQLIRTFEVTPSIALSAGKIEFMSGK
                     PAEAAVILKNGLKDDLSDATNREVTRYYIAALQKQGQDDKALYDKLIQADPKEKELINE
                     LKRE"
     gene            complement(9605..9709)
                     /locus_tag="C1A50_RS22115"
     CDS             complement(9605..9709)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822975.1"
                     /locus_tag="C1A50_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_016822975.1"
                     /transl_table=11
                     /translation="MGLWSKEQLRAFIKEKNQVTAQEVLEVEMDALLG"
     gene            complement(10001..11341)
                     /locus_tag="C1A50_RS22120"
                     /old_locus_tag="C1A50_4715"
     CDS             complement(10001..11341)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688744.1"
                     /locus_tag="C1A50_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4715"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_016822974.1"
                     /sec_met_domain="LANC_like (E-value: 4.7e-64, bitscore:
                     214.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVQNNKSLHNDIIKIVSVISARLTDPQYVQTICSSEQNHVDKQ
                     EEFNWNDISLATGFPAISILYGRLSTVLKDERLKEYAHSYLLSTRESLKKSGASLSLWE
                     GLSGVGFAAYLLSDNGIKYRRFINQINTLILRHGSADLLNAKSGLESGTSINDYDVISG
                     WSGIGRYLLLFSDIPEIRELLIGVLEYLVLLSKDRIINDKQEVPNWYISNEYLLSHEKD
                     EYPFGYFNMGLAHGVPGPLALLSIALLQNIKVPGQIEAIQRYCDWITKWKLEQTDRIQW
                     PLIISYEEFTNDQLYAKKHRDAWCYGSAGVARSLFLAGRSIGDRSLEVLAVNAFKSIYK
                     KSIEEWNIYSPTVCHGYSGLLKITYHMYRDTHDPELQENYQSLLRTVVKMFDEESAFGF
                     YDLYRDSNSTKNLNYVGLLDGVSGIAMTLLDSLYPDEKDWGASLLIC"
     gene            complement(11319..14549)
                     /locus_tag="C1A50_RS22125"
                     /old_locus_tag="C1A50_4716"
     CDS             complement(11319..14549)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822973.1"
                     /locus_tag="C1A50_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4716"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_016822973.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9.3e-176,
                     bitscore: 583.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.1e-16,
                     bitscore: 56.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7e-38, bitscore:
                     129.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKVTNINMFQSLDFFMVRVPLLPIDFYYNLFSESTTYDVTRNKA
                     LSLLTDPVIREAITIASPSLMNSINNVLTNKNTKKMNTVLRAVVNYLIRLSSRATPYGI
                     FSGVSIGLFSELSCLEVGDTRQNRKISRPDMEWIMGLVKYLEKEGNVVKQLAVRTNPTL
                     YLSGTRIKLPFLNYIEQHHDPDVKRMKSSSIKASKPVQLVMDYAQTPIPFANLVKKIQE
                     EYPENNETLITEFLMKLLNQEFLISNLRPPLCIDNMDLPFEYLRKQIAPINNIEYIKKG
                     LDEISEEIKQYDDSPIGKGESLYNQLCIRMRKLVPTKETLQIDMETKVEEAFLSQNVSK
                     DIARSAEILWRLSPDLSNPHWTQYRNDFIEKYGIDCQVPILELLDEDLGLGAPPDYKYP
                     ESRYSLEHPILNAEREKVLANWITNVIKEGKIEIELTDEKLKRIETLSDELLPPTSIEM
                     YVTIAANSEEALKNNEYKIIINPNSGSAGAGKTFGRFGPILDKTAREKITNTYKIQEEY
                     RKDAIFAELVYLTVNSRHSNVVITNKSCSHQIVLGTNYSNVDTSKQISISDLYVGCTHN
                     YFYLKSQSLNKEIIPVSTNMLNYNNAPNVYRFLMEISQERHRSILPFQWGGLSEFPMLP
                     RVKYKNIILSLAKWSLNKNNDELKKCKNEEDWIEGFEKWRGEWRVPRYVYITTSVSDNR
                     VLIDLKNEFFILELFEKYHKLSDSQSLWLTESGFEPSDVWARGKEGRFIAEYVIPLVRT
                     NVEEPLTPKQCEDMNLIQRPIREHSNIIYLPGSEWLYIKLYGMSEREEEFIGNYIRTFC
                     EQVENQGIINRYFIVRYKDPDHHIRLRLHGEESVVCKQLIPAIHMWARRLKVGGLLSKI
                     IFDSYEPEIERYGGKRLISIAERFFAVDSKITVELVSLKYNNKLNVPIEIIGFISVIDI
                     LNQFIPAVERQVTWFHEEEWHKEHVKDFMKDRTFYIILCDVSDNWSSLRNLEYGDYLLS
                     KFQERKKIINEYKEALEHEKDLTNTFSNILGSLIHMHLNRLIGTNRKMERKIMSLLSHS
                     LYHFNESIKHKKKCISKELNVDDSSTKQ"
     aSDomain        complement(13794..14024)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1A50_RS22125_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="4.10E-18"
                     /identifier="RREFam001.1"
                     /label="C1A50_RS22125"
                     /locus_tag="C1A50_RS22125"
                     /protein_end="252"
                     /protein_start="175"
                     /score="56.9"
                     /tool="antismash"
                     /translation="NYIEQHHDPDVKRMKSSSIKASKPVQLVMDYAQTPIPFANLVKKI
                     QEEYPENNETLITEFLMKLLNQEFLISNLRPP"
     gene            complement(14625..14792)
                     /locus_tag="C1A50_RS26135"
     CDS             complement(14625..14792)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038155.1"
                     /locus_tag="C1A50_RS26135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_192811795.1"
                     /transl_table=11
                     /translation="MNSPELVFFEQEDTLDLDLQINDLTLKQAKNPCTSTVTCSVSRCL
                     GTHVTCECWC"
     CDS_motif       complement(14706..14792)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNSPELVFFEQEDTLDLDLQINDLTLKQA"
                     /locus_tag="C1A50_RS26135_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14625..14705)
                     /prepeptide="core"
                     /locus_tag="C1A50_RS26135_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-7.10"
                     /molecular_weight="2675.1"
                     /monoisotopic_mass="2673.2"
                     /core_sequence="KNPCTSTVTCSVSRCLGTHVTCECWC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNSPELVFFEQEDTLDLDLQINDLTLKQA"
                     /leader_location="[14705:14792](-)"
                     /alternative_weights="2693.1"
                     /alternative_weights="2711.1"
     misc_feature    complement(15452..15464)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(16079..16960)
                     /gene="galU"
                     /locus_tag="C1A50_RS22130"
                     /old_locus_tag="C1A50_4717"
     CDS             complement(16079..16960)
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="galU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312210.1"
                     /locus_tag="C1A50_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4717"
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="WP_016822972.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 9.7e-09, bitscore:
                     33.9, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.7e-06,
                     bitscore: 25.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAV
                     ASGIEDIIIVTGKGKRAIEDHFDYSFELEHNLTSKEKWNLLNEVRKPSEMADIHYIRQK
                     EPKGLGHAIWCARKFIGDEPFAVLLGDDIVESENPCLKQMIDVFDEYQRSIVGVKQVDW
                     NEVHRYGIVEGHALTSKISEAERLVEKPKKEEANSNLAIMGRYILTPDIFDILGQQSAG
                     VGGEIQLTDALSKLGEKSPILAYEFDGNRHDVGEKLGFIETTIHYALQHNEIKDEVLAY
                     MRQVIKEIDQQK"
     gene            17148..18179
                     /locus_tag="C1A50_RS22135"
                     /old_locus_tag="C1A50_4718"
     CDS             17148..18179
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688748.1"
                     /locus_tag="C1A50_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4718"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_016822971.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-25,
                     bitscore: 88.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSIISNPVLTLVIPCYNEEEVLPETISRLTVILEELAESELISK
                     HSKMLFVDDGSRDQTWDIIASYNLKNPFVSGLKLAKNAGHQNALLSGLMEAKETSDCVI
                     SVDADLQDDLNAIREFIIKFKEGNDIVYGVRKSRTTDTFFKRSTAQGFYRLMSKMGVNI
                     VYNHADYRLMSKRVLQELANFKEVNLFLRGLVPLIGYKSTEVYYDRHERFAGESKYPLK
                     KMLAFAFDGITSFSVTPIRLISAVGFGMFGISLLIAAYTLISKFLGTTVWGWSSLMLSI
                     WFIGGLQLVALGLIGEYIGKIYKEVKQRPKYIIETILDSQSTFDTENTKKVNNSEREAV
                     AVQ"
     gene            18193..18630
                     /locus_tag="C1A50_RS22140"
     CDS             18193..18630
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016060.5"
                     /locus_tag="C1A50_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GtrA family protein"
                     /protein_id="WP_225164815.1"
                     /transl_table=11
                     /translation="MTNLTLFQNSFFRFLVVGVLNTICGMSVMFLLFNILETNYWLSTF
                     IGNSVGATVSYFLNKRFTFKNDANHGQTIWKFISIILICYILSYCLSYLISHYLISSLS
                     IKNNEILGNVSILIGNVFYTLINYVGQKFIVFSKKTSAQKV"
     gene            complement(18733..21243)
                     /locus_tag="C1A50_RS22145"
                     /old_locus_tag="C1A50_4720"
     CDS             complement(18733..21243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822969.1"
                     /locus_tag="C1A50_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4720"
                     /product="U32 family peptidase"
                     /protein_id="WP_016822969.1"
                     /transl_table=11
                     /translation="MKSAVRREDVELLAPAGDWDCMRAAVANGADAIFFGVEKFNARAR
                     ANNFRMDELPEIMAFLHSYGVKGFLTFNILVFENELEDAKELVDACIDAGVDALIVQDM
                     GLVKMIRDISPDFPIHGSTQMTITSPEAVEFTKPYNMERVVLGRENNLKQIQKIGDQAR
                     LPMEVFVHGALCVSYSGQCLTSEMWGGRSANRGECAQACRLPYDLMVDGEQKPMADVTY
                     LLSPKDLAAIDLMPELIDAGVVSFKIEGRLKTPEYVANVVSKYRKAIDKYFDGDTSKTS
                     KEDIRELQQSFSRGFTHGFLEGTNNKKLVDGTFPKSRGVYLGRVEQILRDGVVCRIDAP
                     LKRGDGIVFDAGDPTQKEEGGRVYDIRRKGVKIEGEAGEGWIVDIVAGRNDVDLRRVHV
                     GDRIWKTNDPALDKRLRQSYETEKPYRVFPVHVRVSGSPGQPLSTWWTDVQKGTTVRVD
                     SELELEIAQKRPMTHELLEEQFGRLGGTVFQLEELDVHLHGDVIVPMRELNSIRRQAVE
                     LLAGERPKPPVYTKRAVEVYGDAATPASSVARGQAELTALCRSLPQVEAALEAGVEFIY
                     ADFEFIKQFPAAVEAVHGAGRRIALVTPRIHMPGENGYHNNILRLQPDAVLVRNPGALY
                     FYMRHRLENPDAHHPQLIGDFSLNIANHKAADLFLDSGCDLVTPSYDLNIQQMVDMLGR
                     TRTDKLEIVIQQHLPMFHTEHCVYCTFMSEGTDYTNCGRPCEDHRASLRDRIGMSHPVR
                     VDEGCRNTVYNAIEQSGAEYLTNFLELGVSRYRVEFLEETPEQVHEVIDLYNRALRGEI
                     SGTQVWKTLKATNQLGVTRGQLVK"
     gene            complement(21677..22117)
                     /locus_tag="C1A50_RS22150"
                     /old_locus_tag="C1A50_4721"
     CDS             complement(21677..22117)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427431.1"
                     /locus_tag="C1A50_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4721"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_045244617.1"
                     /transl_table=11
                     /translation="MITLKAVDKSNWEECAELQPSPEQQRFMVSNLYSIAECQFLDGFL
                     SRAIYNNDVLIGFTMFGLDPDDGNYWIYRFMIDERFQGQGHGYHAMLLVIDEIRKASNR
                     TDMIMIGYKPDNELARKLYRKSGFREEGISPWGEMLAKYSFA"
     gene            complement(22424..24337)
                     /locus_tag="C1A50_RS22155"
                     /old_locus_tag="C1A50_4722"
     CDS             complement(22424..24337)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312214.1"
                     /locus_tag="C1A50_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_4722"
                     /product="stalk domain-containing protein"
                     /protein_id="WP_016822967.1"
                     /transl_table=11
                     /translation="MKHMQRKMMRKLGVGAVALSLLLTALPAVAADQDKNILELRLQSG
                     SNTAIVNGQNANITKPYSKSGALMVPAGVFKKAFNSKIRLAEDNVVKITSGTHVVSLTI
                     GSRTAWVRGHKVTLPAPPEMSSGILMVPLRQVAEGLGGKMEKNGAGIIIRMEAQEEAGT
                     VAEESPNIDNDEGKTQIGNSYYDWSMNYPTGLVIGQGGGDESISTFMDENSAYYMEVHT
                     ALQPVPLNADDLLQQLVQAAKETGETVVDRKSFPKAKVPYARVITKDGDGVLWENRQYY
                     DNGRLYVVYFSDAKATNYKDLAQYAGLLNSFKTSFNAQDKSIKDLSTVVGGTREAGNPD
                     YGVSLKIPAGWKMDDQRMQYESNDGSSFHMKITSAPADGKLENWGQQLQKWLSDSFVST
                     AYEAQKTYPLEVAGVQGLVQEYRYNFGDGWVKEYNVLIQQNGYRYLAEYAVPEKVSKGN
                     DQFNALISSLQIDFQTVANNFGQLEEDDYLADKTKTIKKTSKAYEYTVNIPRYWTAVSD
                     QFELGDIEYQFTGGRFSIKIDNDQSFELTVSQLKDFYDKQAKNYKNIKVEEVKDVTFAG
                     VSAVSFTFHRVEEGIGYTGRQIVLEHNGKTYTVTTTLNDANNTGVQSNALDSTLNSFSF
                     VK"
ORIGIN
        1 ccgtccgagt caattaacct catgttcgca tataccatac caatattttc atcacgttta
       61 agatcagcga ccatcttctc caagaaatgt tcaggaagaa tgttatctgc actggtccaa
      121 gtatggtact cacccttagc tagtttaaaa cctctggata atgttcttgg tattttacga
      181 ttttcctgat ggactaccct aatacgatga tctgctttgg catacgcatc aataatttct
      241 gccgttttat cttttgaacc atcgttaata ataatgagtt caaaatactt ataagattgc
      301 tgcagaatac tatcaatagc tttcgataca taatcctcac cgttatatac aggaagaacg
      361 atcgatataa gatctttctc aaatgcagtc tcgaacttat caagttccag ggaaaatgaa
      421 ttgtctttgg ctactttata attataaaat ttatactcgt accaagttaa taactgattg
      481 tagtttcctt catctttgcg cagatcaaca ggatgatccc ctgcgttagt ccgtttaagc
      541 ttatgcgaca ctttagattt aatcttttta gtaagatcgt ggtgccatag tttttccata
      601 ctctatatcc cttaagaaca tatatcattt tggacttgtg taaaatatgt ttaagtttat
      661 tcgccatttt ccacctttta gagttataaa tattatgaag ctccgtggac agtcttccat
      721 tatattcttg caactcactg aactgggtgt tcagttcatt atattgacca aatagctgtc
      781 tatattgatg gtttaaaata tccaagttgt ttttttcatc attataatcc tgtgtgagtt
      841 gagcgtactg ttgttctaat tcatctttct tttcagacag agatctaata tctgctgaca
      901 tgctgtttat tacattttcc tgatgatcac gcgtttgaat caatgtgtta atctgatccg
      961 tatgctcagc tatgcgttgt ttttgctgtt ctatttcttg gctttgattt tgattatgag
     1021 tttgtaattc attaaattca ttttttagac gtgtatgccc tgctctataa gcctggtcta
     1081 cgtcatcttg taaaaatcta ttaattacat ccatacactt atctatcgtc tctcttcctt
     1141 tgaccggaaa catctctaaa gtaaatttcc ttctttgttg tattagttgt tcatctaaga
     1201 ttgcattaag taaagtttgc ttaatattgt cgttatcgct cacaaaagga acaatgtttt
     1261 gctgaactat ttgttcttcc aaaggtagaa tcccctcgaa cgattctgtt tggggatgct
     1321 ggaatattac aattggagta tccgtaaaca gcgcatcaaa tatagcccca gagccgtcag
     1381 acaatattac atccgcttct tctattaaat gaacaagaga agccttgtga tcaagcactt
     1441 caggaacatg agacttaact agactaaccc gatcatgctc caaaaaagaa gtgccatggt
     1501 gcaattttac cttcatatta aaggtatctg aaatttcttc aatatggttc attacaagct
     1561 caatagacga ttcattccca tacgtaggca aataaagcaa attatattta tccgtttcgc
     1621 gcttcattct ttgaaattta gcatatttaa tcatgcctac gatttcagtc tgagtgtagg
     1681 ctgccagaac cgaggaatca tatagcccat tacaaaaaat gaaatcgaaa ttccgactcc
     1741 atgtatctaa attccagttt ggtttagcca ttccatactg atatctgaac ttataatcgg
     1801 acttaacttc caaataatag gggaggtaag gatagaaggc tattttatat gctttgtcgg
     1861 gtacagcgct tgttagagtc acgtttatac cgttattctt caaataatga taggtatcta
     1921 aggacatgtc tccccaatca tcttcttcaa tgtgagggac ataaatatca caaacgatct
     1981 gctttttttc acattcctca attaaaggct taatcgtttc atataaaaca agattgtgaa
     2041 tgacaaaagc tatagatctg ttcatattca ctgtaaaacc tcttcctttc aggcaaaaat
     2101 ccacttattt tcttaatttc agtaatgtct cattcagtaa agttgatgat gtactcttcg
     2161 tatagggaaa atatataatt ttcactccaa cttccttaaa ctgcaactcg tactggtccc
     2221 aacgttcatt ttgaaaccaa tcatcaccaa cgaacattac gtcatacttt aatttttgcc
     2281 aaacctcaaa tttatccatg gagtcctgag gaattacagt atcaacaaat ttgatatttc
     2341 taacaatctc aattctttcc tcaaaaggaa tgaccgcttt tttgtactta tatgaaacca
     2401 actcatctgt ggtcacaccc acaatgagtt tgtcacagag tgacttagca tttctcaaca
     2461 aattcaaatg tccaatatga aataaatcga agactccgga agtatagccg ataatcataa
     2521 gatttctcct aacgtattta aattgaagtt aaaccatttg tcgaatgtcg tcttcccttc
     2581 aattttttca gaagatagga ctctttcaag ttgaacagga aaacctacct tttttctgtt
     2641 tacaatctct gctgggataa tgtctttaaa aattctcttg agcggagcct taacaactcc
     2701 atccttcatc ttatactgag cgtctacccc tgcaagcctt tcaattaatc tgtaatccaa
     2761 gaaaggagat cttgcttcta ccgaatttaa catcgaggca ctatccagcc ttttgagtaa
     2821 ccctcgcaaa tgggcttgtt gaaagaatgc cgctacgatt ttttgagggg actttaactt
     2881 cataaaaggt gccaatgcat cttctacaat ctctaaatca tcttccgatc cataggtgta
     2941 gagatcacta aaggctcgga tatcaaagtc tgtggtgcta ctagcccatc tgaagatacg
     3001 atcatatcca aagaaaagct catcagcgcc ttctccactt aatatgactg tgttcttagc
     3061 agatgcttgt tgtgtcatat gatacagcaa cacttcgttg ggcacagaca gaggctcttt
     3121 ttttacaatc accagttcac gagctaatga taaaaagcga tcaggatcaa ataatatcgg
     3181 gtgatgaata gtgttatatc ttgttgctgc gatttcagac cactcgaact cattataatc
     3241 ttcaaagcca acagtccaag tatgctctac tccagcgagt gcagtaataa tcgtgctatc
     3301 caagcctccg ctaaggtaac ttccaatttc aacatctgcg attttgcggt actctactgc
     3361 agaacgaatt aaaaactcaa gttcctcatc agaaggcggc tctttctctg aataatcaag
     3421 ttcccaatat ttaataaatt cgccattctc atagtaatat cctgggggaa actcttttat
     3481 ttcattatag acagtacgat tattaaaaaa acatctcatt tttttatatt gtcttacagc
     3541 tgcttgatct aaagaaacgt tgtgaactaa tgggagcaat ggagcaattt cagaactaaa
     3601 aatgaactct tcaccatttt tgttgtaata aagcggcttt actcccatac gatctcgtgc
     3661 tgcaaaaaat gatttgtgct ggacgtctaa aacaataaaa ctgaacattc cattaagcca
     3721 attcaacatt tggggaccat attgaatgta aagcttcaat aaaagttcag tatctgagtt
     3781 tgttctcatt tgaattgaat aagtagaagc taattcttta taattataga tttctccatt
     3841 aaatataatc acatatcttc catcatcaga aaaaaaaggc tgatcacttc tctgatccag
     3901 atctaaaatg cttaatctgt tgtgaccaag cataaaattt tcatgctggt atacacaaag
     3961 cggggccgta ggcccccgat gcttcattat atttaatgaa ttaagaaatg cttctttatt
     4021 tatagctaca ttagaaaaca aaatcccaca cattttatca ccagccttaa ttaataactt
     4081 gcaaatctat tgtattatct acaaatatta aacctggtac gtaattattc tctggcttag
     4141 gaacctcaaa aacagctgct atacttacgc tatccaaata aagaggctca aacggcttag
     4201 gctttaagcc aatagaaatg gtgtatttac cactttcaga caaaagattg cggaaattaa
     4261 agttaacctc aagaatgccc cctgcttgca ttttcgggac taatttggcc ttattgtaga
     4321 tattcatgcc aaacacatct acaccagtat ggtttctaac catgtagcca atggttccct
     4381 cggaatcaat atctttataa tattgtgcca gcaaacgcaa agtaaccatt tcgccaaaag
     4441 ggacctggtt taccacttct ccattgacta acaagtctgc ccttataaaa cgtgcatctc
     4501 ccgttcctga acgaaactca ttggcacgtt ttgcaaaagc aggatcctct tctaacaaca
     4561 acagcgtact ctttttatcc gtttcggaat tcacaaatgt atccaaagat tggacacgct
     4621 tcatatctgc aatttcctgg ttaataatat tttcataaat ttgtgctacg cgcttcactg
     4681 gaccaatttc gaccatgtgt cccttatcaa taagcaatgc tgtatcacaa aaactcttaa
     4741 tggtatccat ggaatgagag acaaataaaa ctgtgctctt tttagagagc tccttcattt
     4801 tggtgataca tttggcctga aaataaatat ctccaacaga caaggcctca tccacaatca
     4861 aaatgtctgg atcaacattg atggctactg caaaggctaa tcgggcaaac ataccgctgg
     4921 agtacatttt gactggttga ttaatgaagt ccccaatatc cgcaaaggat gtaatatctt
     4981 ctaccttctc atccatttct gctttgctat agcccataag cgtaccattt aaataaatat
     5041 tttccattcc agttaaatcc ggattaaacc cagcaccgag ttccaacaga gccgcaactt
     5101 tcccattcac ctttatgctt ccatgggtag gcgtaattac gcctgtaatc atttttaaaa
     5161 gagtcgattt gcccgaacca tttttaccga taatgccaat cgcttgccct tttttaatag
     5221 aaaaggaaag gtcacttatg gctttgaaat cagaatgata tttcttttta aaaggatgaa
     5281 tagcctcttt taaacgttca ttgggattat catatatttt atatatttta gtgacattat
     5341 taacttctac agcaactgat tctgtttgag tcatactctt ctcctcacaa tacatcagca
     5401 aaatgagatt tcattttttt gaaaattttg attcctatcg tacctgcgat gatcacaata
     5461 gcccaaaagt agatcgtcat ggatggatgc tcccagaacc atttgtgatt aataaaggta
     5521 tcacgatatc cttcaacaat atagaaaaca ggattaagtt taaagaaaaa ctgatactta
     5581 tcctcgacaa tattcaaatt ccaaaagatt ggcgtaagcc agaaaaacaa ttgaataaac
     5641 actcctacaa tttgaccaac atcttttaca aaaacaacca atgtcgctgt tatgtaagaa
     5701 atggacaaag aaagaagaat ggtggccaat aaataataaa ggatttgaat gttatacatc
     5761 gtaaattcaa cattgtatat tttgaacata atgaaaagaa cgatgataaa aaacacatgg
     5821 acaaaaagag cagccaaaat ttttaccatt ggtagcaagc ctactcggaa aacaattttc
     5881 tttaccagat aattgttttc aataatacta ttggttgcag ttgacaagct ttccgaaaag
     5941 aataaccacg gcaccatgcc tgttagtaac caaagtataa agggtgtatc accaataggt
     6001 acatttttaa aaccaacctg aaatacgacc caataaacaa gtatagacac cataggatgt
     6061 ataaaagccc agagtacccc cataaatgaa ccaaggtacc tagattgtat atccttttta
     6121 gacaattccc aaagtaactt taaatttttc gaaaagtttt gagttaaatt catacgagtg
     6181 tgtcacgacc ttaaacatgg tttggtaagt ctcttacaat acaacaatgt aaatatgtgg
     6241 gaagtttatt cttgcgatat ggctctgaca gctactatat gctaaaatgt tgacgtatct
     6301 acaagaaaag gagattgtaa accttgtcga atccagtata cgggaaacag gccaaaacgt
     6361 cgacccgtga cgataaaagg ccggctatgt tttgggtgtt aattgttggc atgattttgt
     6421 ttttagcttg ggcccccttc caggcggcgc tttttaatgg tcaaatgctc gactttgaga
     6481 agcctctgta ttgggctttg atcatcagca cgattctgct gatattggga atcgtaacct
     6541 attataagaa tttcaaattg gaagatcaaa gagactggtt ggctgtgctt gttatcttac
     6601 ttccgctgac gttcgtgctt tcattgattt ctgctgcttc tcattatctc gcgatgaaca
     6661 tggtagtggt gcagtgcatc tatgcctcgt tcttcatcat tacattgtac gccttgcgag
     6721 atcggttgag caaccagatc atccaaaccg cgattatgac cgtagcttat attattatag
     6781 gcttcggcct catcaactgg tttggacagt gggtattggc cggacgactc gtggattggt
     6841 tctcaacaat ggtaagcggt aatcgctacg ttgatgccat aaagatagat actaatggtc
     6901 cgcgtctcac ttccgtcttc cagtacgcga atacatatgc ggcatttttg atggcatttt
     6961 tgttcgcagc tatcttttgt ctgatgaagt cgaagacgtg gtatggaaaa gcgactcatg
     7021 cctttatgct ggtgcctata ttggtatcac tgttcctgac actttcacgt ggtggtctca
     7081 taatgctgcc agtcgtattt gttcttttac ttctgttctt taagccagca cggcaaatct
     7141 tatggctttt acattgcgca attgcgggtg tcgtttcact tgctattttg agtcctatta
     7201 caaattgggg attacagctg aatcagacct acaacggtgc tgtggctgct aaaggctggg
     7261 gactgcttct tgggacttcc ttggtgactg cagttgttct atggcttata caaacctctc
     7321 tgggatctcg tttggaaaaa aggatgcacg gtctagcctc acgtaaactc tctaatctgt
     7381 ggctgcctgt tggctctgtg gtcgtgattg gtgtagttgc gttcctgctc attggtacag
     7441 gactacgaac ttttctacca gccaatgtag agacacgtct ggaaaatatc aacttccaac
     7501 agcatagtgt gctggaacgt ataacctttt atcgcgatgc ttccaagcta attgctgatt
     7561 atccgttgat tggcgcaggt ggcggcggtt gggctacgct gtatggaaaa tatcaagact
     7621 atggctacac aagcgcacag gcacataact ttttcatgca gtatctggta gaggccggta
     7681 ttcttggatt cattattttt atggcgttta tcctttatat cttctataaa tacattaaag
     7741 gttacatcaa gagcgatgag gaaaagcggg atagccactt cctttacctg atcttggcaa
     7801 tgtccatttt gctccatagt ctattggact ttaatatgag ttatgtgttc atgggtatac
     7861 tggtgtttat tggactcggg ggtatggctg cagcaatgga tgcacaacct gtaaaacgct
     7921 tggcgatgaa gcctgaaggt ttccgtccga tttatagtat cgtcatttgt gttctcagta
     7981 ttgtgcttct gtttgtaggg ctgcgctttg cacaagccag caatgctgcc tgggaagcaa
     8041 aagcgctgga aagcagcaat tcgttcgaac aacgacaagc tgcttataat aaggatttga
     8101 atctgcgccc aactcatatt gattcaattg ttggtttgtc tagtatgtat tatcaggtct
     8161 acaagcaaac caaacgcgaa gagttctata caggcggtat gaccattgtt gatttggggc
     8221 tgcaggcaga accgtataat agaaatatgc tgtttatcaa aatgcgactt gagcaagcta
     8281 aaggaaacaa tgacaaggca tttgccattt tggaaaataa ccgtgctaac ttcacctggg
     8341 atctggattg gtacaatttg ctgattaccc aagcgtttga atttggcaat aaagctcgat
     8401 tggctaagga ctcagccaag gaacagaagt atttccaagc aggtcttgct gcttatcagc
     8461 aggttctaga tggggtagct catcttaaga cgattccacc tgaaattcaa ttgatacgta
     8521 cttttgaagt aactccaagc attgcgctca gtgctggaaa aattgagttc atgtcaggta
     8581 aacccgccga ggctgccgtc atcctgaaaa acggcttgaa ggacgatctg agtgacgcta
     8641 cgaatcgtga ggtaacccga tactatattg ccgctttgca aaagcaggga caagatgaca
     8701 aagcattgta cgataagctg attcaagctg atcccaagga aaaagaactg ataaacgaac
     8761 tgaaaagaga atagtccctg gagtttagtt gttctctgtt ttgtttattt gaggctgtcc
     8821 cataaatcga tgggatgtcc taaaaaacag aaaagcctat ccttgctaaa atggatgtgg
     8881 gactacccca caacgtgaga caattaaaac accttcaaga gaatgtaatc ctgtcgtaag
     8941 atagggggat aaccttgaag gtgtttttgc gttggcaact agagtgagtt acccgttaga
     9001 aataaaaagt gagagccccc gaaatgagat tggcaggagt acctgtaaaa gaggttatag
     9061 agcagttgga gatacggaat atgacacaga gctcaaaacg tggatgaaaa aacggagtat
     9121 accgtctgga gcagcctgtg ggcaagcaat acagctacgg acaaggtccg tgaacactct
     9181 ttggagcttg aagaagtaag agtagaaaaa atgcacaagg agctggaaag aaggtggaac
     9241 ctaaagtcgt cattgcttgg gtcgagtcca ttcgagaagt cctcaggatc aactcgctca
     9301 cgttgtaagt gaggctctga attggctcga tgacaccacc ttagacgcaa cctaccctga
     9361 aagggacgaa acaacaatca tcgcaataag ctcatcaaat tcattttcta cgcctatata
     9421 cagcgcatct actcatcccg tcaaatcgtc aaagccgttt aagagctatt ccattcattt
     9481 ggctggccgc tcgtcacgtc gaggtacagc aagcttctgc tcgtcatact cgctaacgac
     9541 gttctttctt gctattgctg ttacggctgt ttggcgtcat tttacccttg atctcttgct
     9601 tctcctagcc caggagcgcg tccatttcta cttccaacac ctcctgtgca gtcacctggt
     9661 ttttctcctt aatgaaagct cgcagttgct cttttgacca aagccccatg tattcttccc
     9721 cctttctatg acttccattt tactaaacaa actatcttac agactctagt gaatcaaaaa
     9781 gcgcagattt cggactaatt cagccttgta acctacgctt tttctcatga agttaattat
     9841 aattcgtctc ataggctgtt tcactataaa aaactgcctt tgagataccc ctttttattg
     9901 ttcatctttt gagtggaatt gtaaccctgt tatcgattaa gaacgctaac cagttcctct
     9961 ctgtggtttg agtaattcat ccgttacttt acttattacc ttagcaaatc aataagctcg
    10021 ccccccaatc cttttcatca ggataaagag aatctagtaa tgtcatggct attcccgaaa
    10081 caccgtcaag taaacctaca taatttaaat tcttagtaga attagaatcc ctatataaat
    10141 cataaaaacc aaatgccgat tcttcatcaa acattttaac gaccgttcgg agcaagcttt
    10201 gatagttttc ttgcaattca ggatcgtgcg tgtcccgata catatgatag gtaattttca
    10261 ataatcctga atatccgtgg cataccgttg gtgaataaat attccactct tcgatagatt
    10321 ttttgtatat cgatttaaat gcgtttacag ctaaaacctc caagcttcta tccccgatgg
    10381 atctacctgc taaaaataga ctcctcgcaa cacctgccga accataacac caagcatccc
    10441 gatgtttttt agcgtataat tgatcgtttg taaattcttc gtagcttata attaagggcc
    10501 attgtattct atctgtttgt tccaatttcc attttgttat ccagtcacag tatcgttgaa
    10561 ttgcctctat ttgaccaggt acctttatat tttgaagtaa cgctatagat aataatgcca
    10621 aggggccagg aactccatga gctaaaccca tattaaaata tccaaatgga tattcatcct
    10681 tttcatgtga aagtaaatat tcatttgaaa tataccaatt cggaacctct tgtttatcgt
    10741 tgataatcct atctttactt agaagaacaa gatactcaag aacaccaata aggagctccc
    10801 taatttcagg tatatcagag aacagtaaca gataccttcc tatgccactc catccggaaa
    10861 ttacatcata atcattaatt gacgtacctg attccagccc actttttgca ttcagtagat
    10921 cagcactacc atgacgcaat attaaagtgt taatttggtt gataaatctc ctgtatttta
    10981 taccattgtc agataataga tatgcggcaa atccaacacc agataatcct tcccatagtg
    11041 ataatgacgc tcctgatttc tttaatgatt cacgagtact taaaaggtag gagtgtgcat
    11101 actcttttaa tctctcatcc tttaatacag tacttagtct cccatacaaa atactgattg
    11161 ctggaaatcc agttgccagg cttatatcat tccaattaaa ctcctcttgt ttatctacat
    11221 gattctgctc agaagaacat atagtctgta catactgggg gtcagtcaac ctggcactta
    11281 taacacttac aatttttata atatcgttat gcaggctctt attgttttgt actactgtca
    11341 tcaacgttca actcctttga aatacatttt ttcttgtgct ttattgattc attaaaatga
    11401 tataaagaat gacttaacaa cgacattatc tttctttcca tttttctatt cgtacctata
    11461 agacggttta aatgcatatg aatgaggcta cctagaatat tggaaaatgt attcgttaaa
    11521 tccttttcat gttcaagtgc ctctttatat tcatttatta ttttttttcg ctcttgaaac
    11581 ttagataata agtagtcccc gtattccaaa tttctaagtg aggaccaatt gtccgaaaca
    11641 tcgcacaaaa ttatataaaa agtgcgatcc ttcataaaat cttttacatg ctccttatgc
    11701 cattcttctt catgaaacca agtaacttgc cgttctaccg ctggtataaa ctgatttaaa
    11761 atatcaatta cactaatgaa accaataatc tctataggaa cattcagctt attgttatat
    11821 tttaaagaga ccagttctac tgtaatcttc gaatcaacag caaaaaaacg ctccgctata
    11881 ctaattaaac gtttaccacc gtatcgctca atttccggct catatgaatc aaatattatt
    11941 ttacttagta gacctccaac ctttaggcgt ctagcccaca tatgaatagc agggattagt
    12001 tgtttacaaa caacggattc ctcaccatga agtcgtaacc gtatatgatg atccggatct
    12061 ttatacctaa caataaaata acgatttatt attccttgat tctctacctg ctcacaaaat
    12121 gttctaatgt aattgccaat aaactcttcc tctcgttcag acataccata aagctttata
    12181 taaagccatt cacttcccgg taaatatata atgtttgaat gctctctgat tggtctttga
    12241 ataagattca tatcttcaca ctgcttcggg gtcaaaggtt cctctacatt tgtccttact
    12301 aagggaataa cgtactctgc gataaagcgc ccttctttcc ctctagccca tacgtcactt
    12361 ggttcaaatc cactctcggt taaccataat gattgtgaat cacttaattt atgatatttc
    12421 tcaaataact ctaatataaa aaactcattt ttaagatcaa ttagtactct gttatctgaa
    12481 acagaagtgg taatataaac atatcttgga acgcgccact cccctctcca cttttcaaaa
    12541 ccctcaatcc aatcctcctc gtttttacat ttttttaatt catcgttatt tttattaagc
    12601 gaccatttcg ctaaagataa aattatgttt ttatatttca cacgaggcag catagggaat
    12661 tccgataggc ctccccactg aaaaggcaaa atgcttctgt gtctttcttg tgaaatttcc
    12721 attaaaaaac ggtatacatt gggagcatta ttgtaattta gcatgttggt ggaaactggg
    12781 attatctctt tattcaacga ctgtgacttt aaataaaagt aattgtgggt acatcctaca
    12841 tataaatcag aaattgaaat ttgttttgaa gtatctacat tggaataatt agttcccaac
    12901 acaatttggt gactacatga tttgttggta atcactacgt tagaatgtct actattgacc
    12961 gttaaatata caagttcagc aaatatagca tcttttctgt attcctcttg aattttatac
    13021 gtgttcgtga tcttctctct tgcagtctta tctaggattg gtccaaacct tccaaatgtt
    13081 ttacctgcac ctgcacttcc cgaattgggg ttgataatga tcttatattc gttatttttc
    13141 aaagcttctt cgctatttgc tgctatggta acatacattt ctatagaggt agggggcaaa
    13201 agctcatcag ataaagtctc gatcctcttt aatttttcat ccgtcagttc tatttctatt
    13261 tttccttctt taataacatt tgtaatccag tttgccagaa ccttctctct ctctgcattt
    13321 agtattgggt gttctaaact atatctactc tcaggatatt tataatcagg cggagcccct
    13381 aaccctaaat cttcgtccaa aagctctaag atcggaactt gacaatcaat accatatttc
    13441 tctataaaat catttcggta ctgtgtccaa tgaggattac tcaaatccgg cgacagcctc
    13501 cataagattt ctgctgatct agcaatatct ttagagacat tttggcttaa aaaggcttct
    13561 tctacttttg tctccatatc aatctgcaaa gtttccttcg ttggaactaa ttttctcatt
    13621 cttatacata gctgattgta caaggattcc cccttaccta ttggagaatc atcgtattgt
    13681 tttatttctt cactaatttc atcgagacct tttttgatat attcaatatt gtttataggt
    13741 gctatctgtt ttcgtagata ttcaaaaggc aaatccatat tatctatgca taatggtggt
    13801 ctcaaattgc taattaaaaa ctcctgattc aatagcttca tcagaaattc agttattaaa
    13861 gtttcattgt tttcgggata ctcttcttgt attttcttaa ctagattagc aaaaggaatc
    13921 ggagtttgtg cataatccat cacaagctga accggcttgg acgcttttat cgaactactt
    13981 ttcattcgtt ttacatcagg atcgtggtgt tgttcaatat agtttaaaaa tggcaatttt
    14041 attcttgtac cagataaata caaggttgga ttagtccgca ccgccaactg ttttaccaca
    14101 tttccctctt tctctaaata tttaaccaat cccatgatcc attccatatc tggacgggat
    14161 attttcctgt tctgcctagt atcacccact tccaagcagc taagttccga aaagagacct
    14221 atagaaaccc cagaaaaaat cccataaggt gtagctcttg aagaaagcct gattagataa
    14281 ttcacaactg cccgtagcac cgtgttcatt tttttagtat ttttattggt taggacatta
    14341 ttgatagaat tcataagtga agggctggct atggtgatcg cttcccgtat aacagggtct
    14401 gttaacaaag ataaagcctt gttccttgtc acatcatatg tagtactttc actgaataag
    14461 ttatagtaaa aatcaatagg cagtagtggt actctcacca taaaaaaatc taatgactga
    14521 aacatattta tatttgtaac tttatccact ataggataac ctcctcctga agtaaaagac
    14581 cctggatgta tgaaataata tccagggtca gatttctttt aaagttagca ccaacactca
    14641 caagtcacat gtgtaccaag gcatctagaa acactacaag ttacagtgct tgtgcaagga
    14701 tttttcgctt gctttaatgt tagatcatta atttgtaagt ccaaatcaag ggtgtcctct
    14761 tgttcgaaaa agactaattc tggagaattc atcttaatcc ctcccttcga taaagttgag
    14821 agaacctcaa tgggcaacct ctcaatatat aagacgcatc aagagaaaaa aagtttcttt
    14881 ttattacatc tatttaaaat ttttaccttt tttacacaat gaaagcatct cctgatactg
    14941 gctagtatct cggcctgaca agtcatggag caattgggca tatgaaataa gaacaagtaa
    15001 aaatcatgtt aaggtcgtat cttaacggcg aattgaaacg gataaagctg cctctcggta
    15061 aacaatacag ctataaaaaa gaacctgagc atacattcag agtttgagca accaaaaaac
    15121 ggaaaattgg tttttaaagc aacaattaga cgctctaaaa agtacaaggg agttgaaggg
    15181 ggatgtcacc agagactact tagtacaatg gggaaatcta tttcgggaaa agtgaatttg
    15241 aagtcaagct tgtgatggat aggtcttcct caagccatat acttccacta gaaagcagct
    15301 acgaggccgt ggagaagaac ttctcgtagg aatgttcgcg aactctacat acagcataaa
    15361 actcggtatg gatacaggaa agccacggac ttgtttctta tgagcataag gtcaatcata
    15421 aacttgtaca ataaatcatg tagggtgagc agttacaatg tcatctcaaa ctcaagaaac
    15481 gaaaacgcac agaatcagcc aacttatata gtagtgcatc tctattaaag caccaattcg
    15541 ggatcgaagc cctatgcaaa aaatcgttat ggaaattacg tatttaccgt ttggcgagaa
    15601 aatgttgtat ctgtcgagta tctttgaatt taaatggaga aattgtggca taaagtgtag
    15661 ctgacaagca aaataccgcg tttgtcttgg atacgcttca ccaattaccg tttctaccag
    15721 gtacaatact ccatagcaat caaggcagcg tttataatcc aaagcgtatc agaaagttgg
    15781 aaaggtaaaa agcattacca taagctcccc cgcaaggggg gggactgctg ataatgctcc
    15841 atcaagtcgt tccattccac gttaaagtct gaaacgtgct atctcaaggt ttgagctata
    15901 caacaacgga catcgtcgaa cggacggttc aggactactt tacctactaa ccttaatttg
    15961 cattcaacag aactaaataa ccaatcgcca gttcgtttct agcaactggt ccttaaactg
    16021 aaaagtattt gctctctgtc ttacaaatag ggatcagtcc tacttcttac agtaaggttt
    16081 atttttgttg gtcaatctct ttaataacct gtctcatata agccagcact tcatccttaa
    16141 tctcgttatg ctgtagagca taatgaatgg ttgtttcaat gaatcccagc ttctcgccaa
    16201 cgtcatggcg gttgccatca aattcataag ctaggatcgg actcttttct cccagtttgg
    16261 acaatgcatc cgttaactga atctccccac ctactcctgc ggattgctga cctaggatat
    16321 caaaaatatc aggtgtcaag atataacgtc ccatgatcgc taagttggag ttggcttctt
    16381 ccttcttagg cttttccacc aatcgttccg cctcagagat tttggaagta agtgcatggc
    16441 cttcaacaat cccgtaacga tgtacctcgt tccaatcgac ttgttttaca cctacaatag
    16501 aacgctgata ctcatcgaac acgtcaatca tctgcttgag acatggattc tcagactcta
    16561 cgatgtcatc acccaaaagg acggcaaaag gttcatcacc aataaactta cgtgcacacc
    16621 agatggcatg ccccaagcct ttaggttcct tttgacgaat atagtggata tctgccatct
    16681 ctgatggctt gcgtacttca ttgagcaggt tccatttttc cttcgaagtc aagttatgct
    16741 ccagctcgaa ggagtagtca aaatgatcct caattgccct tttgccttta ccagtaacga
    16801 taatgatatc ttctatacca gatgcaacag cttcttcaat aatatattga atggttggtt
    16861 tgtctacaat gggaagcatc tctttaggca tcgctttggt cgcaggaagg aaccgggttc
    16921 ctaatcccgc agcaggaata attgctttac ggattttcat aggtaaaact ccttttcgac
    16981 aaatcttact aaattattca atagtttgag taacgtttgg aaattgctaa tagtttatta
    17041 tagcacttag tcattgcatt gttatataat ttaagtaaac catattatag actaaaaaag
    17101 atagaaattt gagtaccaga taagccaaaa tttgaggaga gagttctttg gattcaataa
    17161 tcagtaaccc tgttttaacg ttagttattc cctgttataa cgaagaagaa gtactgcctg
    17221 aaaccataag cagacttacg gtgattctgg aagagttggc tgagagcgaa ctcatttcta
    17281 aacatagtaa aatgttgttt gttgatgatg gtagccgtga tcaaacatgg gacatcatcg
    17341 catcatataa tctaaaaaat ccttttgtca gtggtctcaa attggcgaaa aatgcgggcc
    17401 atcaaaacgc tctattatct gggttaatgg aagctaaaga aacctcagat tgtgtgatat
    17461 ccgttgacgc tgacctacag gatgatctca atgccatcag agaattcata ataaaattca
    17521 aagaaggtaa tgacatcgtg tatggggtgc gaaaaagtag aactaccgat acatttttca
    17581 aacgttcaac agcccaaggc ttctaccgtc tgatgagtaa aatgggcgtc aatatcgtat
    17641 acaatcatgc agattaccgt ttaatgagca aaagggttct ccaggaatta gccaatttta
    17701 aagaggtaaa tctcttttta cgtggtctag ttccgttaat aggttataag tctactgaag
    17761 tgtattacga tcgacacgaa cgctttgcag gtgaatccaa atatccttta aagaaaatgc
    17821 tcgcttttgc tttcgatgga atcacctcgt ttagcgtaac cccgatacgg cttatttcgg
    17881 ctgtgggttt tggaatgttt ggcataagct tattaatagc tgcctatacc cttattagca
    17941 agttccttgg taccaccgtt tggggctggt cttctctaat gttgtccatc tggtttatag
    18001 gtggtctaca actcgtcgca ctcggactca ttggcgagta tatcggtaaa atatataaag
    18061 aagtaaaaca aagacctaaa tatattattg agactatttt agattcccag agcacctttg
    18121 atactgaaaa cacaaagaaa gtgaataata gtgaaaggga agctgtagcg gtccaataac
    18181 agatgcgaac aggtgactaa tttgacttta tttcagaata gttttttccg ttttcttgtc
    18241 gtaggtgttc taaatacaat atgcggcatg tccgtcatgt tcttgctatt taatatttta
    18301 gagactaact actggttatc gacctttatc ggtaattctg taggcgccac tgtaagctat
    18361 ttcttaaaca aaagatttac cttcaaaaat gatgcaaacc atggacagac catttggaag
    18421 ttcatctcta ttatattgat atgctatata ctgtcgtatt gtctcagcta tctaatcagt
    18481 cactacctga tctcaagttt gagcattaaa aataatgaga ttctaggcaa cgtgtctatt
    18541 ctaatcggga atgttttcta tactttaatt aattatgttg gacaaaaatt tattgttttt
    18601 tctaagaaaa caagcgccca aaaagtatag caataagagg ctcaatggta attttttata
    18661 taaactagca aatagaaaag ggtatgtgct gtcaaagcac ataccctttt cgctttttct
    18721 atagcagcct tgttacttca ccagttgccc acgtgtaacc cctagctgat tcgtcgcttt
    18781 cagcgtcttc catacttgtg ttccgctaat ttctccgcgc aaggcacggt tatagagatc
    18841 aataacctca tgaacttgct ctggtgtctc ctccaaaaat tccacgcggt aacgggacac
    18901 gcctagttct aggaagttag tcaggtattc cgcgcctgat tgctcaatcg cgttgtacac
    18961 cgtattacgg catccttcgt ccacacgaac cgggtgagac attccaatac gatcacgcag
    19021 ggatgcacga tggtcctcac atggacgacc gcagttggtg tagtctgtgc cttcactcat
    19081 aaaagtacaa tacacgcagt gttcggtatg gaacatcggc aaatgctgct ggatgacgat
    19141 ctccagcttg tcggtacgtg tacgtcccag catatcgacc atctgttgga tgttcaaatc
    19201 atatgacggt gtcaccaggt cgcagccgga atccaggaac aggtcagccg ctttatggtt
    19261 ggcgatattc agcgagaagt cgccaatcaa ttgcggatga tgtgcatccg ggttctccaa
    19321 gcggtgacgc atgtaaaaat acaatgctcc cggattgcgt accagcacag catccggttg
    19381 caggcgcagg atattgttgt gatatccgtt ttcgcctggc atgtgaatac gcggagtcac
    19441 cagcgcaatt cggcgcccag cgccgtgcac agcctctacg gctgccggga attgcttgat
    19501 gaactcgaag tcggcgtaga tgaactccac gccggcctca agcgcagcct ccacctgagg
    19561 gaggctgcgg cacagcgcgg tcagctctgc ctgaccacgt gccacagacg atgccggagt
    19621 cgctgcatcg ccatacacct ctaccgcccg cttcgtgtat acgggtggtt tggggcgctc
    19681 gcccgcgagc agttccaccg cctgacggcg gatgctgttc agctcgcgca tgggtacgat
    19741 gacgtcccca tgcagatgga cgtccaactc ctccagctgg aacacggttc cgcccagtcg
    19801 gccgaactgc tcttcgagca gttcgtgcgt catcggacgc ttctgggcga tttcaagttc
    19861 cagctcagag tccacgcgga ccgttgtgcc tttctgcacg tcggtccacc atgtcgacag
    19921 cggctgtcct ggggagccgc tgacccgcac atgtaccggg aagacacggt acggtttttc
    19981 ggtttcgtac gactggcgca gacgcttgtc cagcgccggg tcgttggtct tccaaatacg
    20041 gtcgcccacg tgcactcggc gcagatccac atcattgcgt cccgctacga tgtcaacgat
    20101 ccagccttct ccagcttcgc cttcaatctt cacgcccttg cggcggatat catatacgcg
    20161 tccgccttct tctttttgcg taggatctcc tgcatcaaat acaataccat cgccacgctt
    20221 gagcggggcg tcgatacggc atactacacc atcacgtagg atttgctcca ctcggccgag
    20281 atacacgccc cggcttttcg ggaacgtacc gtccaccagc tttttgttat tcgttccttc
    20341 cagaaacccg tgtgtaaagc cgcgtgaaaa actctgctgc agctcgcgga tatcttcttt
    20401 gctcgtcttg gacgtatcgc cgtcaaaata cttgtcaatg gccttgcgat atttgctaac
    20461 cacattcgct acatattcag gcgttttcag tcgcccttca attttaaagg aaaccacacc
    20521 tgcatcgatc agttctggca tcaaatcaat ggctgccaga tccttggggg atagcagata
    20581 tgtcacatcg gccatcggct tttgctctcc atccaccatc aaatcgtaag gcaaacggca
    20641 tgcctgtgca cattcaccac ggtttgcaga gcgtccgccc cacatttctg aagtcaggca
    20701 ttggcctgaa taagatacgc acaacgctcc atgcacgaat acttccatcg gaagtctcgc
    20761 ttgatcgcca attttttgaa tctgttttag attattttca cgccccagca caacccgttc
    20821 catgttgtac ggcttcgtga attctacagc ctccggcgag gtaatcgtca tttgagtaga
    20881 accatggatc gggaaatccg gcgaaatgtc gcgaatcatt ttcaccaagc ccatgtcctg
    20941 aacaattagg gcatcgacac cggcatcaat acaggcatca accagctctt tagcgtcctc
    21001 cagctcattt tcaaatacca gtatattgaa tgtcaaaaag cccttaaccc cgtagctatg
    21061 caaaaaggcc ataatttcgg gcaattcatc catgcgaaaa ttattcgccc gtgcccgtgc
    21121 attgaacttt tccaccccaa aaaagattgc atcggctccg ttcgctaccg ccgcacgcat
    21181 acaatcccag tcacctgctg gtgccagaag ctcgacatct tctcttcgta ctgctgattt
    21241 cattattgcc ctccctatat gctgaaaacg aatggtccct cattggagca tcgttgtttt
    21301 cagggcagct atgctgctta cttggtaatc tcattaatgt tccatccact cattccaaag
    21361 ctggttatgt tcagtcaggg atatggaaac ctactaagaa tcttatttct taagcctatc
    21421 tgtctctatc atcttgtccg atcattcaca cgctgaacca tcggtcactt acctgaaacg
    21481 catccaactc aaaaaatccg catcacaaac atctgcggca gaaattattc ttatcttgta
    21541 actaatctag tgtaccagac tgcgccccaa gcttctacac tttccaagcg attcctttaa
    21601 aaatataata ctgaaataca aaaacacctc caatcccggt cagcggtgca ttggaggtgc
    21661 gtcatcatac cattaactag gcaaagctat acttcgcaag catttctccc caaggtgata
    21721 ttccttcctc cctgaaacca gattttctgt atagctttct agcaagttca ttgtctggtt
    21781 tatatccaat catgatcata tcagtccgat tactggcttt ccttatttcg tcaataacca
    21841 gcaacattgc atggtaacca tggccttggc cttgaaatct ttcgtcaatc ataaatcggt
    21901 aaatccagta attcccgtca tccgggtcta aaccaaacat cgtaaaacca atcaatacgt
    21961 cattattata aatcgctcta gataaaaacc catccaaaaa ctgacattcc gcaattgagt
    22021 aaaggttaga taccataaac ctttgttgct cagggctcgg ttgaagttca gcacattctt
    22081 cccaattact tttgtcgact gcctttagcg taattatttt cggattcctc ctatatatcg
    22141 ccttccattt tttatattac caaagcttac tgaccttgcc gtaagaaaaa gctcaatgtt
    22201 gaagcttggt ggtcgtgtta tagcaaaaag gcgaaataag gcctcgtaaa agtatgcagc
    22261 cttcgcactt ccctgcttac ttcactctct aaaagattag gaatatttgg cggtggccag
    22321 cgaagcgggc catttgaatc cgaagaagcg ccagcgatcg taggatcaaa tggcatgcgt
    22381 agcctctacc cactacagct cactaatctt ttatcctcac cctttacttc acaaaactaa
    22441 acgaattcag cgtcgaatcc agtgcgttgg actgtacacc cgtgttgttc gcatcgttta
    22501 atgtcgttgt tacggtatat gttttaccgt tatgctccag aacgatttgg cgacctgtat
    22561 aaccgatgcc ttcctccaca cggtggaatg taaaggacac tgccgacaca ccagcaaatg
    22621 ttacatcctt aacttcctcc actttaatgt ttttatagtt cttggcttgc ttatcataga
    22681 agtccttaag ctgggatacc gttaattcaa aggattggtc gttgtcgatt ttgatagaaa
    22741 aacgccctcc ggtaaattga tactctatat cgcccaattc aaattgatcg ctaaccgcag
    22801 tccaataccg cgggatattc actgtatatt catatgcttt agacgttttt ttgatcgttt
    22861 tcgttttgtc cgccagatag tcatcctctt ccaattgtcc aaagttattc gctactgttt
    22921 ggaaatcgat ttgaagcgaa gaaatgagcg cgttgaactg gtcatttccc ttgcttacct
    22981 tttcaggcac tgcgtattca gccaggtagc gatatccatt ttgctgaatc agcacattgt
    23041 actccttgac ccatccatcc ccaaaattat agcggtactc ctgtactaat ccctgaacac
    23101 ctgcaacctc caacgggtac gtcttttgtg cctcgtatgc tgtggacaca aatgaatcgc
    23161 tcagccattt ttgcagttgc tgaccccagt tttccaattt tccatctgct ggagcagagg
    23221 tgattttcat gtggaagctt gatccgtcat tgctttcata ctgcattcgt tggtcgtcca
    23281 ttttccagcc tgcgggtatt ttgagtgaca caccgtaatc tggattcccg gcctcacgtg
    23341 tgcctcctac tacagtggac aagtctttaa tacttttatc ctgtgcatta aaagaggttt
    23401 taaatgagtt caacagtcca gcatactggg ccagatcttt atagttcgtt gctttagcat
    23461 cggaaaaata aacgacatac agtcgtccgt tgtcatagta ctgacgattt tcccacagta
    23521 cgccgtcccc atccttcgta ataacacgag cataaggcac tttcgctttc gggaaggatt
    23581 ttcggtccac tacagtttct cccgtttcct tggctgcctg caccaattgt tgcaacaaat
    23641 cgtctgcatt cagtggaacc ggctgtaatg ctgtgtgtac ttccatatag tatgcactgt
    23701 tctcgtccat aaatgtggaa atactctcat ctccacctcc ctgaccgata acgagtcctg
    23761 ttggatagtt catggaccaa tcgtagtaac tattcccgat ctgcgtcttg ccctcatcat
    23821 tatcaatgtt cggtgattct tctgctaccg tgcccgcctc ttcttgggct tccatccgaa
    23881 tgatgattcc tgcgccgttc ttctccatct taccgcccag tccttctgct acttgacgca
    23941 aaggcaccat gaggattcct gacgacattt ccggtggagc cggaagtgtc accttgtgtc
    24001 ctctcaccca ggctgtacga ctaccaattg tcagcgatac aacgtgagtg ccgctggtga
    24061 tcttaaccac attatcttca gctaggcgaa ttttgctgtt aaatgccttt ttaaacacac
    24121 cagccggaac catcagtgct ccacttttgg aatagggttt cgtaatattc gcattttggc
    24181 cgttcacgat ggctgtattg ctgccgcttt gtagacgcaa ttccaatatg tttttatctt
    24241 gatctgctgc aactgctggt aaagcggtaa gcagaaggga caatgcgaca gcgccgaccc
    24301 ccagcttacg catcattttt ctttgcatat gcttcacagt aaatctccct ttagctttat
    24361 tttataaatt gatgagccgt tatcttcact ttcccgtagc tgaatctgac gcttccttcg
    24421 aaggcgctat accgtcatct acagcagctc ctgattcatt cgagtcttca agatcttctc
    24481 cagactgaat ggaatcataa atttcaccag tatcctgtgt cagtaccagc ttgcgcttca
    24541 caatatcac
//
