LOCUS       NZ_CP025957            20549 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Paenibacillus polymyxa strain HY96-2 chromosome, complete genome.
ACCESSION   NZ_CP025957
VERSION     NZ_CP025957.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Complete genome sequence of Paenibacillus polymyxa HY96-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2018) East China University of Science and
            Technology, Laboratory of Marine Biochemical Engineering, Meilong
            Road No. 130, Shanghai 200237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Expected Final Version            :: no
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002893885.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:33:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,010
            CDSs (total)                      :: 4,854
            Genes (coding)                    :: 4,742
            CDSs (with protein)               :: 4,742
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 76 of 112
            Pseudo Genes (incomplete)         :: 39 of 112
            Pseudo Genes (internal stop)      :: 14 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:53:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3059108
            Orig. end                         :: 3079657
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025957.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20549
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="14"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20549
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20549
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10549](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10549)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    910..924
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(1004..1018)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     misc_feature    complement(1078..1093)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.04"
                     /tool="antismash"
     misc_feature    2310..2325
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     misc_feature    2836..2849
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.31"
                     /tool="antismash"
     misc_feature    3056..3070
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.3"
                     /tool="antismash"
     gene            complement(3192..4364)
                     /locus_tag="C1A50_RS12965"
                     /old_locus_tag="C1A50_2769"
     CDS             complement(3192..4364)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371417.1"
                     /locus_tag="C1A50_RS12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2769"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_103042461.1"
                     /transl_table=11
                     /translation="MLEKWVQELKDGEQELIAWRRYLHQHPEISFEETNTSAFIADQLR
                     SFGIEVRTNVGGNGVLGFLEGGQPGRTIAFRADFDALPIQDEKDAPYKSTVPGVMHACG
                     HDGHTAALLGVARVLSHHRETLKGKLVFIFQHAEEKPPGGAKFMIEDGCLDGVEAVYGI
                     HLSSEIPLGKIGLKSGPAMAAADAFSIEINGKGGHGARPHQTVDSIVIGSQIVNGLQQV
                     VSRRVDPTESAVLTIGVFQAGTAFNVIADKAKIEGTVRTFNKDIRKEVENEIRSIVKGL
                     TDAYHAGYEIDYLNGYPALVNAEAETERVRELVSRLYGVDAFMDLKPAMGAEDFAYYLE
                     QRPGAFIIVGARNEDERTHFAHHHPRFDFDERALLISGHIFLALALEYLQ"
     gene            complement(4593..5102)
                     /locus_tag="C1A50_RS12970"
                     /old_locus_tag="C1A50_2770"
     CDS             complement(4593..5102)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427739.1"
                     /locus_tag="C1A50_RS12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2770"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_017427739.1"
                     /transl_table=11
                     /translation="MGYNIKSELKLSIKSVPESQKDIIVQLMQFYLYDFTAYLRIDVTE
                     KGTFPAYPDLYQYWTSGEQKLPFLIWRQDIPVGFALVDRMSSNREADYYMAEFFVLRPY
                     RHNGVGTWAAHELFGRFNGRWKVTQMSTNRPAQSFWRKVIGSYTNGEYREQTHPVRGNI
                     SQFFNT"
     misc_feature    5086..5102
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            5212..6312
                     /gene="xerS"
                     /locus_tag="C1A50_RS12975"
                     /old_locus_tag="C1A50_2771"
     CDS             5212..6312
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene="xerS"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687399.1"
                     /locus_tag="C1A50_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2771"
                     /product="tyrosine recombinase XerS"
                     /protein_id="WP_017427738.1"
                     /transl_table=11
                     /translation="MNIQKIIDRRKLDEKLPDLPWYVQQFMDYKLPDLSPSTLLEYVRD
                     YEAFFSWLRSEGLSAGETNAQVTLEELETLHMDSITGFRLFLSTKREGSNSRITISRKL
                     SSLRSLFHYLSQIAEDENFYPLLKRNIMAKVEIKRVHKPKDTAAKLKGKILEEEELLEF
                     IGYIYEGYGQDLADNKQALYSYELNKERDACIASLILNSGLRVSEIVNLNMDDLDINNK
                     LLYVYRKGNNDETFKTPVYFREQSKDDLALYLSLRHTRYRAPKKEKALFVARPNGSAEG
                     KRMTKRAIQAMIIKYAKRFGKPYLTVHKLRHSFATDYYLQNDIYKTKEQLGHASTETTE
                     VYAHLTDKTMSQAIERRIETQTDSAN"
     gene            complement(6321..6872)
                     /gene="mobB"
                     /locus_tag="C1A50_RS12980"
                     /old_locus_tag="C1A50_2772"
     CDS             complement(6321..6872)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="mobB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371420.1"
                     /locus_tag="C1A50_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2772"
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="WP_103042462.1"
                     /transl_table=11
                     /translation="MKTKYPFVCQIVGFKNTGKTTFLGGLIRYAQQSGLRVAVIKHDGH
                     EFEMDHEGTDTYKHRQAGAEGVAIVSAGRTAILEEHSRPVIGLIRHFQAYDCVLLEGFK
                     QEKYPKLIMVREQSDAQLVQELTNVQGVVVWEYHMDWAQDYYSDEKTVQIFPADASEPA
                     GCWLLEQIQRHKMGFQTEQG"
     gene            complement(6869..8146)
                     /gene="glp"
                     /locus_tag="C1A50_RS12985"
                     /old_locus_tag="C1A50_2773"
     CDS             complement(6869..8146)
                     /GO_component="GO:1990586 - divisome complex [Evidence
                     IEA]"
                     /GO_function="GO:0061599 - molybdopterin molybdotransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006777 - Mo-molybdopterin cofactor
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="glp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371421.1"
                     /locus_tag="C1A50_RS12985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2773"
                     /product="gephyrin-like molybdotransferase Glp"
                     /protein_id="WP_103042463.1"
                     /transl_table=11
                     /translation="MKQTPLNTEKFQRKAVKVEEAQSRIASYVQQGEREDVGLEQAHGR
                     YLAMDLTAPHPYPRFRRSGMDGYAILASDTEVCSTGQEIWLHVIDEIPCGTVSDKRVET
                     GMAVRIMTGAQLPEGADTVVMLEATQLREENGQTYVGLKKRMEVGKNVTQIGHEIKEGQ
                     LLLSKGTCVGAGHVSVLATFGVHRVPVYKKPRVAVFSTGSELLAVDEPLQPGKIRNSNT
                     YMLASQIREAGGEPFILQAIHDDLNLARASVREAIAAYDIVVTSGGVSVGDFDIMGDLV
                     RQKDVNMLFNKVTMRPGSVTTAAVIDGKLLFALSGNPGACFVGCELFVRPTIQMMLSSA
                     HPYLQTWTAKLGADYTKVNNYTRFVRSSLEIRSGQVYAIPARVDESSAMVTIKDSDCLI
                     VVPPTTEGLHEGEEVHVLVLQGGQVT"
     gene            complement(8343..8582)
                     /locus_tag="C1A50_RS12990"
     CDS             complement(8343..8582)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820734.1"
                     /locus_tag="C1A50_RS12990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_103042464.1"
                     /transl_table=11
                     /translation="MVADKNEDVTCTSFYTIKMARLASGYSELIACNILGMSMNELKHI
                     EEDSSDLTIARAQQMSSLYEVSIDSIYFGKNNIT"
     gene            8671..8886
                     /locus_tag="C1A50_RS12995"
     CDS             8671..8886
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024835.5"
                     /locus_tag="C1A50_RS12995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_016820733.1"
                     /transl_table=11
                     /translation="MQKLTRGKCLLKEELKSHGRTQSWLARRTGYSRQQISNWIAGRDK
                     MSFEAAVLISRILECKAEDLYEWELA"
     gene            complement(9157..9891)
                     /locus_tag="C1A50_RS13000"
                     /old_locus_tag="C1A50_2774"
     CDS             complement(9157..9891)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820732.1"
                     /locus_tag="C1A50_RS13000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2774"
                     /product="hypothetical protein"
                     /protein_id="WP_016820732.1"
                     /transl_table=11
                     /translation="MEEGKRILATPLLDDNSLGDCSFFCENHLVAIELWKPKSNYHIPL
                     FHTSHGRFTVPTTLHECSVGLPTFCNLDGSNLVNITQVDKIVTGDYGGGQVVFKNQDIK
                     ESINSANLSRWKQIYENAMNADREIRYIFGSEIKVVGKAAVSGFFKVGNMLSVDMWEPK
                     KNYYVPRFHSGDRSYSIGLTAQACREAFPYLYPAYKDTLINLELVCEIESNAFGGLVRF
                     EGSDFTCSMSHNKLKALKKLWK"
     gene            complement(9897..10028)
                     /locus_tag="C1A50_RS25660"
                     /old_locus_tag="C1A50_2775"
     CDS             complement(9897..10028)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427735.1"
                     /locus_tag="C1A50_RS25660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2775"
                     /product="hypothetical protein"
                     /protein_id="WP_016820731.1"
                     /transl_table=11
                     /translation="MDKKLARALSISLGNYANESTKKEKTIFGAKPVPAELKKTEKN"
     gene            complement(10001..10549)
                     /locus_tag="C1A50_RS26100"
     CDS             complement(10001..10549)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.5"
                     /locus_tag="C1A50_RS26100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="accessory gene regulator ArgB-like protein"
                     /protein_id="WP_103042465.1"
                     /sec_met_domain="AgrB (E-value: 5.6e-20, bitscore: 69.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETLSRHIASEIKKADPDGPTSVEVMEYAIGVKITEISAVLMVA
                     VMAWITGHFFGALLALATIMFVRRFSGGVHFSNLTLCVCFTTAICVTIPFVSLSLSTIL
                     IINACSLLMFVVYAPNHFIYINKTKHHKYYKTICILVCILNFFIQSHIICLSLIIQAFS
                     ILPLWKGGERKWIRNWREL"
     gene            complement(10500..11213)
                     /locus_tag="C1A50_RS13010"
                     /old_locus_tag="C1A50_2776"
     CDS             complement(10500..11213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820730.1"
                     /locus_tag="C1A50_RS13010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2776"
                     /product="hypothetical protein"
                     /protein_id="WP_016820730.1"
                     /transl_table=11
                     /translation="MLSAFLYIILGFFDALAAVTLVLKLYMLPVWENRRKIIFYAMGIA
                     LFSFLMREVIGMPKFDFPLQYLLMVLFLRFGLGIKTYLAAFSAGSGLTAYINLQLFVYI
                     FANFFGVAQPGVISDTAGSSIYVIQLASIFTAYFISFVMGKYNFGFSFIIQPPHDFLKG
                     ENYLSPLNKMFIIGSLISFVTILVTLYMLYNSNTIGLLSISLLTFGISYFLSEKGDYED
                     ARNAIEAHRIRNKES"
     misc_feature    11334..11348
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.08"
                     /tool="antismash"
     gene            11480..11713
                     /locus_tag="C1A50_RS13015"
                     /old_locus_tag="C1A50_2777"
     CDS             11480..11713
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820729.1"
                     /locus_tag="C1A50_RS13015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2777"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_031461564.1"
                     /transl_table=11
                     /translation="MALSDNFKKLRIKYHLTQQELAEIAGVTNKAISAWESGLSEPRMG
                     AIEKIARHLHIKKSSIIEEDGIEHISPDRRSK"
     misc_feature    complement(11490..11502)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            complement(11847..12602)
                     /locus_tag="C1A50_RS13020"
                     /old_locus_tag="C1A50_2778"
     CDS             complement(11847..12602)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310483.1"
                     /locus_tag="C1A50_RS13020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2778"
                     /product="DUF4247 domain-containing protein"
                     /protein_id="WP_019687402.1"
                     /transl_table=11
                     /translation="MGKRTWQYALKVIVALSLFVSVLSGCGAPNVKDTYPLESVSGSGN
                     STSYVYRAAGKTVPEVAEELKEQRTPEQISPQSNERMFLVYSDEWYHLQQDPAKKEDTL
                     IEIDSKKYVEQNYSSSFLKGYLTATVLDALFDSLRGSGSYRGYSSRDVYRPSQGQYRAP
                     TAQEKKAIPPITVERKGSVTRRGKNSDSSVGSSGSLFDRGSSSSPSRGSISRDRGSSGG
                     SSIFDSPRKSYSKPKTRSGSGKISRRSRR"
     gene            complement(12616..13122)
                     /locus_tag="C1A50_RS13025"
                     /old_locus_tag="C1A50_2779"
     CDS             complement(12616..13122)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010348250.1"
                     /locus_tag="C1A50_RS13025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2779"
                     /product="DUF4178 domain-containing protein"
                     /protein_id="WP_017427734.1"
                     /transl_table=11
                     /translation="MSVWKRISNLFAKPEPPKAEKSMLHLNPGDICEVSLVTYEVVGRV
                     HNRARNAVVLTLQDGNQVSYLHIEERETLQFGLYQAIDGRLDNPEEVPTILELDDTTYH
                     LEEQYFGHVTVMGRAPFRQGGEQHVWQYQSDDYHLLRVEWQDGRFMLYEGEEVITGDVK
                     VIRAS"
     misc_feature    13099..13113
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.68"
                     /tool="antismash"
     gene            complement(13147..13554)
                     /locus_tag="C1A50_RS13030"
                     /old_locus_tag="C1A50_2780"
     CDS             complement(13147..13554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820726.1"
                     /locus_tag="C1A50_RS13030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2780"
                     /product="DUF350 domain-containing protein"
                     /protein_id="WP_013371429.1"
                     /transl_table=11
                     /translation="MHFLETMKAMLVWTGAGAILLFVLMYVDSLFTKYKDFAEVKAGNM
                     AVTVRMIMKLIAQGYILSGSIATANNLLEALVYSVIAFIILLVLEVIVRLLLRYWAQFD
                     LDKGTQEGKIGFGLFSGALHLVGALIITACF"
     gene            complement(13684..14352)
                     /locus_tag="C1A50_RS13035"
                     /old_locus_tag="C1A50_2781"
     CDS             complement(13684..14352)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432515.1"
                     /locus_tag="C1A50_RS13035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2781"
                     /product="PspA/IM30 family protein"
                     /protein_id="WP_013371430.1"
                     /transl_table=11
                     /translation="MSIFKRLRDLTMSNINAIIDKAEDPVKMTDQYIRDMQEDLEDAEK
                     AVAAQIAIEKRFKQQYEEQAALVKKREEQAHTAAKAQNVDLARRALEEKKSAEQKMNEF
                     QAGYEQNKAAADNLRGKLDEMRRQLTEMKNKRETLVARYNAAKAQTEINKAMNGFSSDT
                     ATAGLKRMEEKMLQAEARAEASNEMASKEKSLDEEFKELDKKSAVDDELAALLKQYENK
                     "
     gene            complement(14439..15461)
                     /locus_tag="C1A50_RS13040"
                     /old_locus_tag="C1A50_2782"
     CDS             complement(14439..15461)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371431.1"
                     /locus_tag="C1A50_RS13040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2782"
                     /product="NADH:flavin oxidoreductase/NADH oxidase"
                     /protein_id="WP_103042466.1"
                     /transl_table=11
                     /translation="MTDLFTPYQLKGLSLRNRIVMPPMCQYSVEAKDGKPTDWHYVHYV
                     SRAVGGTGLIIVEMTAVHPDGRITDRDLGIWSDEHIPAYRKMVEEVHKYGAKIAIQLGH
                     AGRKAEDAEPPVGPSSIPFSERFKEPHALTRAEVKELVQAYKEGARRAVEAGFDTVEIH
                     GAHGYLIHQFHSPLTNTREDEYGQDLSLFGVEVIRAVKEVLPADMPVLMRISAKEYVQD
                     GYDVEYIAAIGERYRDAGVDIFHISSGGEGPIGSSGGPSARAGYQVDLAHTIREKLNVP
                     VIAVGLLDDYEDARRVVQHNEADLVAIGRAMLRDPYWALHASRALKVQADIPEPYLRGF
                     "
     gene            15765..16571
                     /locus_tag="C1A50_RS13045"
                     /old_locus_tag="C1A50_2783"
     CDS             15765..16571
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820724.1"
                     /locus_tag="C1A50_RS13045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2783"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_103042467.1"
                     /transl_table=11
                     /translation="MRYRGVLPCLALLLAFSSFPVHADTPPNIGTPHPKEAAVATSVYQ
                     SKDRATPTLAMLRKKHADIFKMCGPHTRQIALTFDDVPDSRYTPQVLDVLHANGIKATF
                     FIVGHRAEKHPGIIRRIIREGHAIGNHSYTHPDFRKATPERFRHQITKTERILEASAGF
                     RPRLIRPPYGEITEPQIQWARRHGYMIVNWNVDSLDWKGLSKTQIQRNVIPATRPGSII
                     LMHAGGGQSSNLQGTVQALPGLIHSLKAKGYKFVTVPRLLHTSERK"
     gene            complement(16771..17439)
                     /locus_tag="C1A50_RS13050"
                     /old_locus_tag="C1A50_2784"
     CDS             complement(16771..17439)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687404.1"
                     /locus_tag="C1A50_RS13050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2784"
                     /product="3D domain-containing protein"
                     /protein_id="WP_103042468.1"
                     /transl_table=11
                     /translation="MKHLKHIGKTMKFAVLAAAIAGLAQTAGVANAASLHTAKEGDTFF
                     LLAQRYGVSVDDLTKANPDIASNNIYAGLQIKMPDEKSVKAASDSKPQLLTEKAPANER
                     PTIEAWGKTFNYSKVVDVKATAYSAAADENGKWGAVDYYGNPLKLGTIAVDPKVIPMGT
                     KVLVTGYSHPGLPDHSFVAVARDQGSAITGKRIDIFIPGNKSFVNDFGFQNVKLYVIDK
                     "
     regulatory      complement(17446..17615)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(17859..18581)
                     /locus_tag="C1A50_RS13055"
                     /old_locus_tag="C1A50_2785"
     CDS             complement(17859..18581)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371435.1"
                     /locus_tag="C1A50_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2785"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_013371435.1"
                     /transl_table=11
                     /translation="MITVKQLRKSFGKNEILKGIDIDIAKGEVVVIIGPSGSGKSTFLR
                     CMNLLEQPTEGEILFEGEPITARGHNINATREKMGMVFQHFNLFPHKTILQNLTLAPTQ
                     VKKQSGKEAEKIALELLRTVGLEDKKNTYPNQLSGGQKQRIAIARALAMQPHVMLFDEP
                     TSALDPEMVGEVLDVMKKLAEGGMTMVIVTHEMGFAREVGDRIIFMDNGQIIEQGTPEQ
                     VFGTPSHDRTRDFLAKVL"
     gene            complement(18568..20031)
                     /locus_tag="C1A50_RS13060"
                     /old_locus_tag="C1A50_2786"
     CDS             complement(18568..20031)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371436.1"
                     /locus_tag="C1A50_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_2786"
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="WP_017427733.1"
                     /transl_table=11
                     /translation="MKKAYRFTALVLTAVILLLAGLPMLTAYGSEGKPQKKLVVGMSAD
                     FPPYEFHKVINGQDTIVGFDVEIAKEIAKDLDAEMVPEDMSFDSLLPALQSGRVDLVLS
                     GMTPTDERRKSIDFSDVYYRSKQVIMVRPEDKDKYSTMAALKGEKLGAQKGSIQEEIAQ
                     KVPNASVTSLDKISDLVLQLRTKRINAVVIEDTVAKGYTLDGTVTLAKAVPEDEGAETA
                     VGIRKGNAELLASVNKTLARLKADGSIEKFSTEASALSADRQVSSNSIVDIFLKYRSFY
                     ATGIGYTLLLSALGVLFGFIIGLIISLLRMSGIRIIEWLGTAYVEILRGTPMLVQLMII
                     HYGVALTLGVNFTPLQSGIITLSLNSSAYLAEIFRAGIQAVDRGQMEAARSLGMGRGKA
                     MRHVILPQAFKSILPAIGNEFITIIKESSIISTIGMVDIMYQAQVIKNITYEGLSPFVI
                     AAAIYFVMTFSLSKLLGLWERKLRASDHR"
     misc_feature    complement(20092..20105)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.49"
                     /tool="antismash"
ORIGIN
        1 gctagggaaa cgggtgagct tcctgtattg gttattttaa acttggaact gatcgtatta
       61 cttgttgcag atacattccc attgaaggat tgcaccttca gagcaccctc gcctgttccc
      121 ggctcacttg gcgtatcccc tttcaccgta atcgtgaaca acgcatcatt gcctgtacta
      181 aaatggaagt tgagcgttgt ctctccttta ggaagtttag ataaatactt gttggtaaga
      241 ataactgttt cttcactaac cgtataatct tcacctttgt tcagtgccac acttccctgc
      301 ttgatcgctt ctagtgtatt accgttaaga gtaagcctga cagtaatatc ggtattactg
      361 ttagccactc cataagttgc agccgtcggt gtaatacttg cttgtccggt agatggctga
      421 tcaccaccca cacgatctgc caccagaatg ccgcggccat tcgttcccag ataagcacgt
      481 ccgtaaaccc gaggatcccc aataatggtg gtcacacgag catattgatg cttatcatca
      541 ttaatgcgta cccagtttgc gccagcatcg tccgaacgat aaaatccacg agttccgtca
      601 atcttaccaa cgataaacac tgctgcattc gtacgattgg gtgctgcttt gccaaagcct
      661 acaaaatccg cctcctgcac ttgatcaagc tggttgaatg taacacctga atccttggaa
      721 tgccataagc cgtatggccc tccgtcctcg gagcctccag caaaccacac atctccttcc
      781 gctcctcgta cagcaccaat atctgcattc cctacacttg gcaaaccagt aactgtggat
      841 ggtgtgaagg atgcgcctcc atcaacactt acatatattt tcccagcagc aaacgcgtag
      901 tatttgttag gatttactcg gtcagaggcg atctttgcat tagctggaac tcccgtgctt
      961 gctgtccatg agtttcctcc ggttttggaa taaaatacac ctttgtccga tgtactccac
     1021 agcaatccat taccatttgc cgctacagcg atgctgcctc ctcctgctgt actggaaggc
     1081 tcgctattag ctttgtacca gttcgctccg ccatcattgg ataatccgat agatttggcg
     1141 tttggatctt ttttatagtc cgctttacct acccgagcca taaaagaagg gcttaactcg
     1201 gcataatcaa tgctttcgct gcttgtaaag gttggattat ccagcatttt agcaggagcc
     1261 ttgaacaggt catcatgtct gaatccggag acatcaccca ctgcactcac cagaggagct
     1321 ccagttggag ggctcaccaa atccaaaatc gccgtttctt ctaccccttt agccgctacc
     1381 gaaatgtcca gcttacctcc cttgtcccaa ttggtcagat ttttagagcc ataaatcgta
     1441 gctcctgtgc cgtacagcat atgatctgaa ttaaatggat ctatttccag atctccaatc
     1501 atccagccca gcttgggcga tacttccggc ggtgcaggat tggcattgaa agtcagccaa
     1561 ggcgcaccgg atatatccag attgtacttc agcttacgag ctggataacc atcaaattcc
     1621 caaatagggc tccaggttgc cccactatca gtactgcggt aaatcgtttc atccggccac
     1681 caggcattca acgttgcaac cataagtgta cctggcttct gggcgtccac tgtcagtcca
     1741 ccatatccaa aatgattgtc tgcgctgctg ctggcaacgg ggctaatgtt agtccactgt
     1801 ccactggctg tattcagttt ccacagctca ccctttgttc catcatacgg tccagctcca
     1861 tcgctgtaag aaatatacag gtcgccatct ggcgataaaa cgccgtgatg tggcaaatag
     1921 cctgtaggct ggcccgctat agcagaccag gttgtcccgc catcagtact gcgatagaca
     1981 ctttgctttt tatctgcgac acccacatag atggtctgtg ttgctttact ggaagagccc
     2041 gtttttttgt caaaagtgat ccaggctaaa ccgacaatat cactggtgta ttcattggaa
     2101 gggtcctgta catacgtccc cggattcgga aaactactca ccttgctcca ggtcgccccg
     2161 taatcggagc ttttccacaa tccattacca cttcgagctc cgaagaataa tatattgttt
     2221 ttattcggat caattgccag acgttcaccc attgagcgtc ccggcatatt gcctcctacc
     2281 ttaaagggaa gctttgtagt ttgccacgta ttccccttgt cggtagagcg cataatttgc
     2341 ccgttttgtt tatcccagga attagtatac gtgcctgtag ctatatatac acgattcgga
     2401 tccacagggt cggtggctag tgcatcgaca ccatttttgt tccaattctc ccagcccaca
     2461 gaatccgtca gcggaatcca gctttcactc gcaggattcc agcggtaagc tcctccaata
     2521 tctgtacggg catagatcag atctttttcc gtttcattaa aaataatacc aggtacaaaa
     2581 ccacctccac cgcctgtaac gacacttttc caagtataat cgtcacttgg agcagcatgg
     2641 gtgggtgcta tcatgcctgt ccaggaagca cccgctacta taagcgccaa acatacaatt
     2701 ctcaacctgc tttttgcctt agtcaatgaa ttcaacctcc ttctccgtaa tcatttaaaa
     2761 atgcaagtca tttcgagcta aaagtaagca gtcaattgcg gattcgttcc tatcgttatt
     2821 attccattca tcaatcaaac aagcgttctc tcaagctcac ctccagtaat ccaatagatt
     2881 tgcaatcttt tttgttagcg cttacatcgg tgtctgctca aaagattcgt catctttttc
     2941 tcatttcctt gtgtgaaaaa tcaagataat gtaatagtat cttctgcttg ataacttgta
     3001 ataaaagagt tggcttccac ttacagttga tacctcttat aaattactaa tatgaatttt
     3061 tcatataatg aattattttc tttaaatttc attcgaacga ggtaccaaaa tactttgatt
     3121 tacagcaaaa aaccgcgcta tgcgcggttc gggcttccgt aatgctatgg ctattcatta
     3181 ataggttgaa attactgcaa atattcaagc gccagcgcta aaaaaatatg tcctgagatg
     3241 agtaacgcac gctcatcaaa atcaaagcga ggatggtggt gagcaaaatg ggttcgttca
     3301 tcctcattac gagcgcccac aataataaaa gctccaggtc gttgttctag ataataggca
     3361 aaatcctctg ctcccatggc cggttttaag tccataaaag catctactcc atacagccta
     3421 ctgactagct cacgtacccg ttctgtttcg gcctcggcat tcaccagagc aggataacca
     3481 ttcaaataat caatttcgta tcccgcatga taagcatccg ttagaccttt tacgatacta
     3541 cgaatttcgt tttcgacttc cttgcgtata tccttattaa acgtacgtac ggtcccttca
     3601 attttggctt tatctgcaat tacattaaag gcagttcctg cttgaaatac cccaatcgtt
     3661 aacactgctg attccgtagg gtccactctg cgactcacga cctgttgtag tccgttcaca
     3721 atttgacttc caataacaat ggaatccact gtctgatgcg gtctggcgcc atgtccgccc
     3781 ttgccgttga tttcaattga aaaggcatcg gcagcagcca ttgccggccc actctttaag
     3841 ccgattttgc ccagtggaat ttccgaggaa aggtgaatac catatactgc ttccacccca
     3901 tccagacaac catcctcaat catgaatttg gctccgccag gcggtttttc ttcggcatgt
     3961 tgaaaaataa acacaagctt tcccttcagt gtctcacggt gatggcttaa cactcgtgcc
     4021 actcctagca acgcagctgt atgaccatca tgtccacaag catgcataac accgggaacg
     4081 gtcgatttat aaggcgcatc cttttcatcc tgaataggaa gtgcatcaaa atcagcacga
     4141 aatgcaatcg ttctacctgg ctgcccgcct tctaaaaaac cgagcacacc gtttccaccg
     4201 acattcgttc ttacttcaat accaaaagag cgtaattggt ctgcaataaa tgcagatgta
     4261 ttcgtttcct caaaagaaat ctctggatgc tgatgcaaat atcttctcca cgcaatcagt
     4321 tcttgttcac catcttttag ttcctgaacc catttctcca gcatattacc ctcttttcct
     4381 attgaattta tatacttcta tccttatctt accataaatg attccaataa gttatatatg
     4441 aattaccaaa taactgtata cctgcgtttt taccaatgtc aatgcaagtt ctaattggaa
     4501 cgatccatga acagaaggct tgaaatgaca acaaaaaagc cgacaaaata ttctcctcgg
     4561 cttttttctg gtggttttct attatgaatt tttcatgtat tgaaaaactg acttatattc
     4621 cctcgtactg gatgtgtttg ctccctatac tcaccattcg tatagcttcc aatgaccttg
     4681 cgccaaaagg attgggctgg tctattcgtg ctcatctgag tcaccttcca tcgcccatta
     4741 aaacgtccaa acagctcatg agccgcccaa gtgcccacgc cattgtgtcg ataaggacga
     4801 agtacaaaga actcagccat gtaatagtca gcttctcgat tgctagacat tcggtcaacg
     4861 agtgcaaagc ccacaggaat atcctgtctc cagatcaaaa aaggcagctt ttgttcgccg
     4921 ctcgtccagt attgatacaa gtctggataa gccgggaatg tccccttctc agtgacatca
     4981 attcgcagat aggctgtaaa atcgtataag taaaattgca tgagctggac aataatgtcc
     5041 ttctgcgact ctggtacact ctttatggac agcttcaatt ctgatttgat attatatccc
     5101 atactttcac ctctcttggc ggtcagcttg ttctttactt tgattactcc catccagtgc
     5161 tgttcaaaat atgctaaaat acatgtatta tgaccggacg aggtgaaccc tatgaacata
     5221 caaaagatca tcgaccggcg caaactggat gaaaagttgc cggatttgcc atggtacgta
     5281 cagcaattta tggattacaa gcttcccgac ctatccccct ctactttgct ggaatatgtg
     5341 cgggattacg aagctttttt ttcatggctt cgctcggaag gcttgtctgc cggtgaaacg
     5401 aatgcccaag ttacactgga agaattagag acactccata tggatagcat tacaggtttt
     5461 cgtttgttcc tgtctaccaa acgcgaaggc tccaattccc gtatcaccat ttcacgtaag
     5521 ctatcgtcct tgcgttcact ctttcattat ttgagccaaa tcgctgagga tgaaaacttt
     5581 tatccgttgc tcaagcgcaa tattatggcc aaagtcgaaa ttaagcgcgt acataaaccc
     5641 aaggatacgg ccgccaagct caaaggaaaa atactggaag aggaagaact gcttgaattt
     5701 atcggctata tttatgaagg ctatggacaa gatttggctg ataacaagca agccctatac
     5761 tcctatgaat tgaacaagga gcgagatgcc tgtatcgcaa gtcttattct gaactcggga
     5821 ctgcgtgtat ccgaaatcgt caacttgaac atggacgatc tcgatataaa caataaattg
     5881 ctgtatgtgt accgtaaagg aaataacgat gaaactttta aaacgccagt atatttccgc
     5941 gagcaatcca aagatgatct cgcactttat ttatccttaa gacatacccg ttatcgcgct
     6001 ccaaaaaaag aaaaagctct ttttgtcgcg cgacccaacg gcagtgctga gggcaaacgg
     6061 atgactaaaa gagcgattca agcaatgatc atcaaatacg ccaagcggtt cggcaagccc
     6121 tatttgaccg ttcacaagct ccgtcattcc tttgctactg actattattt acaaaatgat
     6181 atttacaaaa ccaaggaaca gctgggtcac gcttcgacag aaacaacgga agtctatgcc
     6241 cacctgactg acaaaacgat gtctcaggcg atcgaacgac ggatagagac tcagactgac
     6301 tccgctaatt agtggccctc tcatccctgc tctgtctgga atcccatttt gtgcctctga
     6361 atctgttcga gtagccagca gcctgccggt tcgctggcat cggcaggaaa tatttgcacc
     6421 gttttttcat ctgagtagta gtcctgagcc caatccatgt ggtactccca aactactact
     6481 ccctgtacat ttgtcagttc ctgaacaagc tgcgcatccg attgttcccg caccatgatc
     6541 agcttcggat atttttcctg cttgaaacct tccagcaaca cacagtcata ggcctgaaaa
     6601 tgccggatga gtccgatcac aggccgacta tgttcctcta aaatggcagt tcttcctgcc
     6661 gaaacaatcg ctacgccttc ggcacccgcc tgtcggtgct tgtacgtatc tgtcccctca
     6721 tgatccatct caaattcatg accatcatgc ttgatcacag ctacacgcag tcctgactgc
     6781 tgcgcataac gaatcaaacc tccgaggaag gttgtttttc ctgtattttt gaatccgacg
     6841 atttgacata caaatggata tttcgttttc acgtcacctg tccgccttga agcaccagta
     6901 cgtgcacctc ttcaccttcg tgcaagcctt ctgttgtggg aggaactacg atcagacaat
     6961 cgctgtcctt aatcgtaacc atagcactgg attcatctac tcgcgcagga atcgcatata
     7021 cttgcccact acgtatctcc agagaactgc gtacaaagcg ggtatagttg tttaccttcg
     7081 tataatctgc tcctagcttc gccgtccagg tttgcaaata cggatgtgcc gaagataaca
     7141 tcatttgaat agttggtcgt acaaacagct cacagcctac aaagcatgca ccgggattgc
     7201 cagagagcgc aaataacagc ttaccgtcta tcactgcggc tgtggttaca ctacctggac
     7261 gcatcgtaac cttgttgaac agcatattca catctttctg tcgtacgagg tcacccataa
     7321 tatcaaaatc acccaccgac actccaccac tcgtaaccac aatatcatag gcagctatcg
     7381 cttctcggac agaagcacga gcaaggttca aatcatcatg aatggcttgc agaatgaacg
     7441 gctctcctcc tgcctctcta atttgagaag ccagcatata tgtattactg tttcgaattt
     7501 tccccggttg taacggctca tccactgcga gcaattctga tccagtggaa aagacagcca
     7561 ccctcggctt cttgtaaaca ggcacccgat gtacaccaaa agtagccagt accgagacat
     7621 gccccgctcc cacgcaagtt cccttactga gcaaaagctg accttcctta atctcatgac
     7681 caatttgtgt cacatttttg ccaacttcca tacgcttctt caagccaaca tatgtctgtc
     7741 cattttcctc acgcagctgt gtcgcctcca gcatcaccac cgtgtccgct ccttcaggta
     7801 gttgtgctcc tgtcatgatg cggactgcca ttcccgtctc cacccgcttg tccgatacgg
     7861 tgccacaagg aatttcatca atcacgtgta gccagatttc ctgaccggtc gaacagactt
     7921 cagtgtccga ggcaaggatc gcatagccgt ccataccaga acgacgaaag cggggatacg
     7981 gatgtggcgc agtcaaatcc atcgccagat agcgaccatg tgcttgctcg agccctacgt
     8041 cctccctttc accctgttga acatagctag ctatcctgct ttgtgcttct tccaccttaa
     8101 ctgctttacg ttggaatttt tctgtgttta atggcgtctg tttcatgttc tcactccgtt
     8161 cttctaaaat accctctttc tgttataacg ctaaaaccgt tatctggcaa atccgaacgg
     8221 tgtttattgg atactgcaag tctctatccg ccaaaaaaca gcctgaatat cacatcgcgg
     8281 ctgtttttgg tatattttgg tttttctgtt ttgcatgtca ttacgtcagt tttctacgta
     8341 tattaggtta tattattttt accgaaatag attgaatcta ttgaaacctc atacaacgag
     8401 gacatttgct gcgctcgagc tattgttaaa tccgatgaat cttcctctat atgttttaat
     8461 tcattcattg acataccaag tatattgcaa gctattaact cactataacc tgaagcgagt
     8521 cgtgccatct ttattgtata aaagctagtg caagttacat cttcattttt atctgcaacc
     8581 atccaatcaa ctccacaata taattgataa aaaagtaatt tacctgtata ctctgaacga
     8641 aacacttttc ccctgttagg agcaagtaag gtgcaaaaac ttactcgggg gaaatgcctt
     8701 ttgaaagagg agctcaaatc tcatggacgc actcaatcat ggctcgcccg acgaactgga
     8761 tattcgcggc aacaaatatc caactggatc gcgggacgtg acaaaatgtc attcgaggcg
     8821 gcagtcctca tttctaggat attggagtgt aaagctgagg acttatatga gtgggaactt
     8881 gcctgacaaa caggcatttc cttcgggccg tttgtacatg ccggcattta cattatatat
     8941 cccgctttca ccctcctttt cttatatgta gattgttttc atcttaattt aaaagattgt
     9001 tatttttttc ataatcaaat tttatcacat agaaaatgat taaaaacggg aaatatgtcg
     9061 aattaaatcg aacccgtccg gcttatccta gtctaactga ttattgactt attcatttaa
     9121 atctggtaac aaaaatgacc cctgaatttt catgggtcat ttccacaatt ttttaagtgc
     9181 tttaagttta ttatgagaca tcgagcaagt gaagtctgat ccttcgaatc gtaccaaacc
     9241 tccaaatgcg ttagactcaa tctcacaaac caattctagg tttatcaggg tgtctttata
     9301 agcaggatat agatacggaa aagcctccct gcaagcttgt gcggttagcc cgattgaata
     9361 agagcgatct ccagagtgaa aacgcgggac ataataattt ttttttggtt cccacatatc
     9421 cacactaagc atattcccta ctttaaaaaa accgctcact gccgctttac ccactacctt
     9481 aatttccgat ccgaaaatat aacgaatttc tctatcggca ttcattgcat tctcatatat
     9541 ttgtttccat cgagataaat ttgctgaatt tatactttct ttaatgtctt gatttttaaa
     9601 aacaacctgc ccccctccat aatctcccgt aacgatcttg tccacttgtg tgatgttaac
     9661 caaattagat ccgtccaaat tgcaaaaagt gggtaagcct acggaacatt catggagggt
     9721 ggtgggaact gtaaatcttc catgagaagt atgaaaaagc gggatgtgat aattgctttt
     9781 gggcttccac aattcaatcg caactaggtg attctcacaa aaaaaagagc aatctccaag
     9841 tgaattgtca tcaagcaatg gagtagctag gattcgcttt ccctcttcca ttaaattcag
     9901 ttcttttctg ttttcttcag ctcagctggt acaggtttag cgccaaaaat tgttttttct
     9961 tttttggtag actcgttagc gtaattacca aggcttatac ttaaagctct cgccaatttc
    10021 ttatccattt tcgctcacct cctttccata aaggaagaat actgaatgct tgtataatta
    10081 aagataaaca tattatgtga gattgtataa aaaaatttaa tatgcaaacc aaaatacata
    10141 tcgttttata atatttgtga tgtttggtct tgttaatata gataaaatga ttgggagcat
    10201 atactacaaa cattaataat gaacaagcgt taattatcaa aatcgttgat aaacttaaag
    10261 agacgaaagg tatagttaca catatggccg ttgtaaaaca gacacaaagg gtaaggttgc
    10321 tgaagtgtac ccctcctgaa aatctcctta caaacatgat tgtagccagg gctagtaatg
    10381 ccccaaaaaa atgtcctgtt atccaggcca taactgcgac cattagtact gccgaaattt
    10441 cggtaatttt cacaccaatc gcatactcca tcacttctac acttgtaggt ccatcaggat
    10501 cagctttctt tatttctgat gcgatgtgcc tcgatagcgt ttctagcatc ctcgtaatct
    10561 cctttctctg ataagaagta cgaaattcca aaagtcagca atgagatgga aagtagtcct
    10621 atcgtattgg agttatagag catatacaaa gtaacaagaa tcgtgacaaa tgatattaag
    10681 gagcctataa tgaacatttt attaaggggt gataggtaat tttcaccttt caaaaaatca
    10741 tgtgggggct gaatgataaa tgagaaacca aagttgtatt tccccatgac aaaagaaata
    10801 aagtacgcag taaaaataga agctagctgt ataacgtaaa tggaagagcc agctgtatca
    10861 cttataacac ccggttgtgc tactccgaaa aagtttgcaa agatatatac aaatagctgt
    10921 agattaatgt aagctgtaag accggaacca gcagaaaaag ccgcaagata tgttttgatt
    10981 cctaaaccaa atcttaaaaa gagaaccatt aataaatact ggagcggaaa atcaaattta
    11041 ggcatgccta taacttctct catgagaaag gaaaacaagg ctatgcccat tgcatagaaa
    11101 attatttttc ttcgattttc ccacacggga agcatataaa gcttcaagac caaagtaact
    11161 gccgctaaag catcgaaaaa accaagtata atatataaga aagcagataa cacagttaca
    11221 tcatcctcct atttcgcctg atgtaattgt atattttact aatagatgtg gcaatgaaat
    11281 aatctagtaa actggaattt tttgtatgac tataagatga aattttcttc ccctggcttt
    11341 ctttttcaaa ctcgacatcc attcgtggta ataaaaaaag tcaccccaag tgagcgacgt
    11401 tgcttttgcc aatgtattat gttggttttt tttcgatatc aaggttataa tctacttaat
    11461 ttggggtgga gggattattg tggctttaag tgacaatttc aaaaaattac gtataaaata
    11521 tcatttgact caacaagagc ttgctgagat cgctggggtt accaataaag caatttcagc
    11581 ttgggagagc ggactttctg aaccacggat gggtgctata gaaaagatag ctcgtcatct
    11641 ccatatcaaa aaaagcagta tcattgaaga agatggcatt gagcacataa gccctgatcg
    11701 caggtcaaag tagacggcaa taaaatcgaa gtgagggagc atccattcaa tttacattag
    11761 taaatgttaa acaacaaaaa aaggaactgt gcaagacagt tccacagttc cgcaaacaac
    11821 tttagaagaa aataaaatat tacccatcat cgtcgacttc gccggctaat tttacctgag
    11881 ccgctgcgtg ttttaggctt actataagat ttgcgcggtg aatcaaatat gctggaacca
    11941 ccgctgctgc ctcggtcacg tgaaatcgag cctctgctcg gtgaactgct ggagcctcga
    12001 tcgaatagac ttccgcttga tccaacgctg gaatccgaat tttttcctct acgggtaact
    12061 gaaccttttc gttccaccgt tatcggcggg atcgcttttt tctcctgtgc tgttggagca
    12121 cgatattgcc cttgtgaagg tcggtataca tctctgctcg aataacctcg ataggagcca
    12181 gacccccgca atgaatcgaa cagagcatcc agcacagttg cagttaagta tccttttaga
    12241 aagctggaac tgtaattttg ctcgacatac tttttactgt cgatttcaat gagtgtatct
    12301 tccttcttag ctggatcttg ctgcaaatgg taccattcat cgctgtatac cagaaacatc
    12361 cgctcattgc tctgaggcga tatttgttcc ggtgtacgct gttctttcaa ttcctccgct
    12421 acttcgggaa ccgttttgcc tgccgcccga tatacgtacg aggtcgagtt tccgctacca
    12481 ctaacggatt ccagcggata cgtatctttc acatttggcg ccccgcagcc gcttagcacg
    12541 gatacgaaca agctcagcgc cacaatgacc tttaatgcat attgccaggt gcgtttgccc
    12601 atgtgtaacc ctctcctagc tagcccgaat aaccttgacg tctccggtaa tcacttcttc
    12661 tccttcataa agcataaagc gaccgtcctg ccactctacc cgcagtagat ggtaatcatc
    12721 agactggtac tgccaaacat gttgctctcc cccctgccgg aaaggagcac ggcccataac
    12781 ggtaacatgc ccaaaatact gttcttccaa atgatacgtt gtatcatcca gttctaaaat
    12841 ggtcggtact tcctccgggt tgtctagtct gccatcgatg gcctgatata gtccgaattg
    12901 cagtgtttcc cgttcctcaa tatgaagata actcacttga ttaccatcct gaagcgtcaa
    12961 aacaacggca ttccgagcac gattatgtac acgacctacc acttcatagg tgacaagcga
    13021 cacttcacaa atatcaccag gatttaagtg aagcatgctt ttttccgctt tcggcggttc
    13081 aggcttggca aatagatttg aaattcgttt ccatacactc atggtcatat tccctcctta
    13141 ctttgcctag aagcatgctg taatgatcaa ggcacccacc aaatgcagcg ctcctgagaa
    13201 caagccgaaa ccaattttac cttcttgggt acctttatcc aaatcaaact gtgcccaata
    13261 ccgcaacagc agacgcacaa tcacttccaa aacaagcaag atgataaagg caatcacaga
    13321 atacacaagc gcttcgagca aattattagc tgtagcaatt gaacccgata aaatgtatcc
    13381 ttgtgcaatc agcttcataa tcatccggac tgttacagcc atatttccgg cttttacttc
    13441 ggcaaaatcc ttatactttg taaataaaga atcgacatac attaatacga acagcaaaat
    13501 agcacctgcg cccgtccata ccagcatcgc tttcatcgtt tctaaaaaat gcatttgcta
    13561 ccatcctcca catcttcttg actacatata ttgatttacg cccccaggca gggaaaagcg
    13621 aaggagataa cgtttctcct tcgcttactg agccatcaca ctagcggcaa tgcttaaaag
    13681 ttcttattta ttttcgtatt gtttcagcaa agcagcaagt tcgtcgtcca cagcactttt
    13741 cttatccagc tctttgaact cttcatccag cgatttttcc ttggaagcca tttcgttgct
    13801 cgcttcagca cgtgcttctg cttgcagcat tttttcctcc atacgcttta atccagcagt
    13861 tgccgtatcc gagctaaaac cattcatcgc tttgttaatt tcggtttgcg ctttagctgc
    13921 attataacgg gcaaccagtg tctcgcgctt gtttttcatt tcagtcagct gtctgcgcat
    13981 ttcatccagc ttaccacgca ggttgtcagc tgcagctttg ttttgctcat aaccagcttg
    14041 gaactcgttc attttttgtt cggcagattt cttttcttcc agcgcacgac gagcaagatc
    14101 cacattttgt gcttttgcag ccgtatgagc ctgttcttcg cgttttttca ccaaagctgc
    14161 ctgttcttcg tattgctgtt taaatctctt ttcaatagca atttgagcgg ctaccgcttt
    14221 ctctgcgtct tccagatcct cttgcatatc acgaatgtat tgatccgtca ttttaactgg
    14281 atcttctgcc ttgtcgataa tggcgttaat gttagacatc gtaagatctc ttaatcgttt
    14341 gaaaatagac atgtgaagtt cctcctagaa ttgaatgctt aaattttaag ctctgtacac
    14401 atgtttacgc aagctttgca aagaggtttc agaaatatct aaaaaccgcg tagataaggc
    14461 tctggaatat ccgcctgtac ttttagcgcc cgtgatgcat gcagcgccca atagggatca
    14521 cgcagcatgg cacgccctat ggctaccaga tcagcttcat tgtgctgaac gactcggcgg
    14581 gcatcctcat aatcatccaa taagccgaca gcaatgacag gcacattcag tttctcacgg
    14641 atggtatgag ccaaatccac ctgataacca gcacgcgcag acggacctcc gctggaacca
    14701 atcggaccct caccaccaga agaaatatgg aaaatgtcta cacccgcatc acgatatcgt
    14761 tcccctatgg ctgctatgta ttcaacatca tatccgtctt ggacatattc tttggcagat
    14821 atccgcatta gcacaggcat atcagcagga agtacctctt taacagcacg tatcacctca
    14881 acaccaaaca gtgataaatc ctgcccatac tcatcttctc gggtattggt taaaggagaa
    14941 tggaattgat ggattagata gccgtgagcg ccatgaatct ctaccgtgtc aaaaccagct
    15001 tctaccgccc ggcgcgcccc ctctttgtag gcttgaacca gttccttgac ttctgctcgc
    15061 gtcaaagcgt gcggctcttt aaatcgttca ctaaagggga tcgaggacgg gcctacaggt
    15121 ggctcagcat cttcagcctt gcgtccggca tggcctaatt gaatggcaat tttggcacca
    15181 tacttgtgga cttcctctac cattttacga tatgcaggaa tatgttcatc actccaaatg
    15241 cccaaatcac gatccgtaat gcgcccatcc ggatgaaccg ctgtcatttc cacaattatg
    15301 agtccagtcc ctcctaccgc gcgactcaca taatggacat aatgccaatc cgtcggtttg
    15361 ccgtccttgg cctccacgct gtattggcac attgggggca tgacaatccg atttcttaaa
    15421 gaaagcccct ttaattgata aggagtaaac aagtcggtca cttttatcca tccttccctc
    15481 aattccaagt ctgtagcatt atgaatagca tccccattat acaccagctg tcacggtata
    15541 ccgaatcctt tgtaaggcta aaacttacga aaatgctcca gttttcgttc atgtttaaga
    15601 gaatatgcgc gtttacttcg tcatcttcac ggatatccgc ttcatgatgt gcttctcttc
    15661 agtcgtgtag gacttcactc aatcaccagc ataattttaa taggacaggt acataatagc
    15721 tgagagcacc actaggtacc actgcacgga aagggggaat acaaatgcgg tacaggggag
    15781 tgttgccatg tttagcactg ttactagcat tttcaagttt tcccgttcac gctgacacgc
    15841 ctcccaacat cggaacgccc catcccaagg aagctgctgt cgctacttcg gtatatcaaa
    15901 gtaaagatcg agctactcca acattagcga tgctacgaaa aaagcatgcg gacattttta
    15961 aaatgtgcgg cccgcacacc cgccaaattg ccttaacctt tgatgatgtg cccgattcaa
    16021 ggtatacgcc gcaggttttg gacgtattac acgcaaacgg tattaaagct acgtttttta
    16081 tcgtcggcca tcgtgcggaa aagcatccgg ggatcatacg ccgcatcatc cgcgagggtc
    16141 atgctatagg aaaccattcc tatactcatc cggatttcag gaaggccaca ccagaacgct
    16201 ttcgccacca gattacaaaa acagaacgca ttttagaagc cagcgcaggt tttcggccca
    16261 gattgatacg accaccctat ggtgaaatca cggagcctca aattcagtgg gcgcgtcgtc
    16321 atgggtacat gatcgtcaat tggaatgtgg actctctaga ctggaaggga ttaagcaaaa
    16381 cacagattca gcgtaacgtg atcccggcta ccagacctgg ctccattatt ttaatgcatg
    16441 caggtggagg tcaaagttcc aacttgcaag gtactgtcca agctttgccg ggtctaatcc
    16501 actctttaaa agctaagggc tacaagtttg tcacagtccc ccggctactt cacacatcgg
    16561 aacgaaaata acagtatgtc taagcctcgt atataccaac aacgtaaaaa ggctgccttg
    16621 acgagcagaa tgcttctgct tgtaagacag ccttttttag cgataaacga ccgtactgat
    16681 aagaagtcgt cccagttata tgttgtgtgc tataatatta agtttacata atatatatta
    16741 tgtttaatga aatcaaatat atgcacaatg ctatttatca ataacgtaca gtttcacatt
    16801 ttggaagccg aagtcgttca cgaatgattt gttgccaggg ataaagatat caatccgctt
    16861 tccggtaata gcgctgccct gatcacgggc aacggctaca aaagaatggt ctggcaagcc
    16921 gggatgggaa tagcctgtaa ctagcacctt tgttcccata ggaatgactt tcgggtctac
    16981 tgcaattgta cccagtttaa gcggattacc gtagtaatcg actgcacccc atttgccatt
    17041 ttcatcagct gcggctgaat atgctgttgc tttaacatca acaactttac tgtaattgaa
    17101 tgttttgccc catgcttcaa ttgttggcct ctcattcgct ggtgctttct ccgtaagaag
    17161 ctgtggtttc gaatccgaag ccgccttcac acttttttcg tctggcattt taatttgtag
    17221 acctgcatat atgttgttgg acgcaatatc cgggttagcc ttcgtcaagt catctaccga
    17281 taccccataa cgttgagcaa gcaaaaagaa agtatcgcct tctttggcag tatgaagcga
    17341 agcagcattt gctactccag ctgtctgtgc caatcctgca atcgctgcgg caagcaccgc
    17401 aaatttcatg gtttttccaa tatgttttaa gtgtttcaaa gatatgtacc tcctctgtta
    17461 tgcctgcgaa gttagctgtc ggattcggac tcaggagaag ccctatgctt gtgcaattca
    17521 cccctaggca tattccacaa catctatatg acgcattgga ataattgccg ttgttacgtc
    17581 ccccgcactt cccatggttt gagcccagca cctgagtaat tgttatcatt gctgctgccc
    17641 cggtaagttt tggcttactg cataatatca caattttgta accttatctg catgaaaatg
    17701 ttgggaatct tgaacatcat actatatcca ttacaatttt gtcatcaaaa atcggttttt
    17761 tgttacgaaa atatggagat atggtgacaa aaggagaaaa gccctccgtg aaatatcatc
    17821 acgagagggc tttgtcaata attcataaaa gcattttctt acagcacttt agccagaaaa
    17881 tcacgggtac gatcatggct tggagttccg aaaacttgct ccggcgtacc ttgctctata
    17941 atttgaccgt tgtccataaa gatgattcgg tctcctacct cacgagcaaa gcccatttca
    18001 tgcgtcacga tcaccatcgt catgccgcct tcagcgagct tcttcatcac atccagaacc
    18061 tctccaacca tttcagggtc cagggcagag gtaggttcat caaacagcat tacgtgcggc
    18121 tgcatggcga gagcacgtgc tatcgctata cgttgctttt gaccgccaga taactggttc
    18181 gggtaggtat tcttcttatc ctcaagaccc acggtccgca ggagctccaa cgcaattttc
    18241 tccgcttctt tccccgattg cttcttcacc tgcgttggtg caagcgtcag attctgcagt
    18301 attgttttat gcggaaacag attaaaatgt tggaaaacca tccccatctt ctcccgagtc
    18361 gcattaatat tatgaccacg ggccgtaatc ggctcaccct caaacaagat ttccccttct
    18421 gttggctgtt ccaacagatt catacaacgc aaaaacgtac ttttccccga accactcggg
    18481 ccgataatga cgactacttc acctttggcg atatctatat caatgccttt taaaatttca
    18541 ttcttaccga atgatttacg cagttgttta acggtgatca ctggctctca acttcctttc
    18601 ccataaaccc aacagcttag ataagctgaa tgtcattaca aaataaatag cggctgcgat
    18661 tacgaatgga cttaagcctt cgtaggtaat attcttaatg acctgggctt gatacataat
    18721 gtccaccatc ccaatggtcg aaataataga agattcttta atgatcgtaa tgaactcatt
    18781 accaatagca ggcaatatag atttaaatgc ttgcggtaaa ataacgtgac gcatcgcttt
    18841 gcctcgtccc atcccgagcg agcgggcagc ttccatctgt ccacggtcta cggcctgaat
    18901 accagcacgg aaaatttcag ccaaatatgc cgaactattc agagacaaag taattatacc
    18961 ggactggagt ggcgtaaaat taacacctaa cgtcaaagca actccgtaat gaatgatcat
    19021 aagctgcacc agcataggtg tgccgcgcag tatctctaca tatgcggtac ctagccactc
    19081 gataatacga ataccactca tccgtagcaa ggatatgatc aggccaataa tgaatccgaa
    19141 cagtactccg agcgcagaca gcaatagagt gtagccgata cccgtagcgt agaaactgcg
    19201 atatttcaaa aatatatcta caatgctatt cgaagaaacc tgtctgtcag cagacagtgc
    19261 actcgcttct gtagaaaatt tctcgatcga tccgtccgct ttcaggcgag ccaacgtttt
    19321 atttactgaa gcaagcaatt ccgcatttcc tttacggatg cctacagcag tttctgctcc
    19381 ttcatcttca ggtactgctt tggcaagtgt tacggtaccg tctagcgtgt atcctttagc
    19441 aacggtatct tcgattacaa ccgcgttgat acgcttggtc cgaagctgga gtaccagatc
    19501 ggatatttta tccaatgagg ttacagaagc attaggcact ttttgcgcaa tttcttcctg
    19561 gatactcccc ttctgcgcac cgagcttctc tccttttaga gcagccatcg ttgaatattt
    19621 gtctttgtcc tctggacgta ccataatgac ttgcttggaa cgatagtata catccgaaaa
    19681 atcaatgctc tttctgcgtt catccgtcgg tgtcatacca gacagcacca agtctacgcg
    19741 accactttgc agagcaggca gcaaagagtc aaaactcatg tcctctggga ccatctctgc
    19801 atccagatcc ttggcgattt ccttggcgat ttcaacatca aacccgacaa tggtatcctg
    19861 accgttaata actttgtgaa actcatacgg cgggaagtca gcactcatac ccactacaag
    19921 ttttttctgt ggctttcctt ccgatccgta tgcagtgagc ataggaagac cagccaacag
    19981 caagataacc gccgtcaaaa ccagggcggt aaaacgatat gcctttttca atcttttttt
    20041 ctctccttaa attctttata ataaataaga ttgtgtcatt ataaatgaat atgcatgatt
    20101 atgcaatgaa tgttatagta caattttagt atatctatcg cagtacctac attacagcat
    20161 atataaagga gttttcagca tgaattttaa acagaccatt caacacacca ttgaacagca
    20221 tgccgagcgg tttaaggaca tttcgttgta tataggcgca aaccctgaac ttggaaacga
    20281 ggaattcctg gcctctgccc gtctaaaaga agaacttgcc tttcacggtt ttgaagttca
    20341 ggcacccata ttgggtatag aaacggcctt tattgctact tacaaagcag tcaagcctgg
    20401 accagttgtt gcttttctgg cagaatatga cgcgctgaaa ggtttagggc acgcctgtgg
    20461 acaccatttg atatgcatga tgagtacagg cgctgccgtc ggtctcaaat cgatcatcga
    20521 cgagactggt ggagaagtac gtgtatacg
//
