LOCUS       NZ_CP025957            24068 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Paenibacillus polymyxa strain HY96-2 chromosome, complete genome.
ACCESSION   NZ_CP025957
VERSION     NZ_CP025957.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Complete genome sequence of Paenibacillus polymyxa HY96-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2018) East China University of Science and
            Technology, Laboratory of Marine Biochemical Engineering, Meilong
            Road No. 130, Shanghai 200237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Expected Final Version            :: no
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002893885.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:33:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,010
            CDSs (total)                      :: 4,854
            Genes (coding)                    :: 4,742
            CDSs (with protein)               :: 4,742
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 76 of 112
            Pseudo Genes (incomplete)         :: 39 of 112
            Pseudo Genes (internal stop)      :: 14 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:53:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1410682
            Orig. end                         :: 1434750
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025957.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="6"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24068
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14068](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            242..1162
                     /locus_tag="C1A50_RS05950"
                     /old_locus_tag="C1A50_1276"
     CDS             242..1162
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="C1A50_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1276"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_103042268.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDNLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERIDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTEGEVQTAEIAFEVNDAEQAYTLAGAGRVEGNQLLLHLEREQIAEMNSLLVANGVK
                     VYAIRPVARTLEDQFLEVTGGGSIG"
     gene            1155..1937
                     /locus_tag="C1A50_RS05955"
                     /old_locus_tag="C1A50_1277"
     CDS             1155..1937
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="C1A50_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1277"
                     /product="ABC transporter permease"
                     /protein_id="WP_031463078.1"
                     /transl_table=11
                     /translation="MADFFKLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIVLVLMVTLSSWLMLSKDAPAGSVPLFSDPISYETLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTIYNSIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSNLTFSLAVLAAYYVVFIAIAWVVFVKRDVST"
     misc_feature    2111..2127
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2198..3283
                     /locus_tag="C1A50_RS05960"
                     /old_locus_tag="C1A50_1278"
     CDS             2198..3283
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="C1A50_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1278"
                     /product="AI-2E family transporter"
                     /protein_id="WP_025364270.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTSGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFLFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGLMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIVAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYHLFLERRVEDIME"
     gene            complement(3323..3787)
                     /locus_tag="C1A50_RS05965"
                     /old_locus_tag="C1A50_1279"
     CDS             complement(3323..3787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="C1A50_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1279"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_031463079.1"
                     /transl_table=11
                     /translation="MFKESKKKLSTPATTDTLLANGTSFEGTIEAEANIRIDGHFQGDI
                     YSTRTVVIGESAVVRSDIIARDVILAGKVFGSITTEGRLTITSTGELYGNTATPTLVIS
                     EGGVLNGTSQMNQTMDAESPAAIEKSEDENQSSFSQDIEDSQASLQPEAG"
     gene            complement(3833..4864)
                     /locus_tag="C1A50_RS05970"
                     /old_locus_tag="C1A50_1280"
     CDS             complement(3833..4864)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="C1A50_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1280"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_031463080.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSAAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATSIRERL
                     QRVTELEQQMQQFIRKHGNSSSASSNKSTITPLSWDASGHTGGELIAVHENTALLARQA
                     MDDFQEIEALLDTVERTVPRSIQQANAVQQNLERQQAAQLLQTRRLALAEQGKPSIWPV
                     GSRRMTSSFGYRSDPFTGKSAFHSGVDIAGQSGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4987..6417
                     /gene="cls"
                     /locus_tag="C1A50_RS05975"
                     /old_locus_tag="C1A50_1281"
     CDS             4987..6417
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="C1A50_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1281"
                     /product="cardiolipin synthase"
                     /protein_id="WP_017426475.1"
                     /transl_table=11
                     /translation="MLWLLLVLIIFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKVVRKAGSQLFREFREHLWAQTKVIENVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFDAMLKAMEQAQHHIHVEFYIFRADEIGKKFQEVMIR
                     KAREGVKVRFIVDGVGSYHLPYSFIRTCNEAGIEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGTIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDGVYFLQNVFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQELCFGALTVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGIDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVLFATSALERLSADFVEDISNSSKIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     misc_feature    5007..5020
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.61"
                     /tool="antismash"
     gene            6612..7556
                     /locus_tag="C1A50_RS05980"
                     /old_locus_tag="C1A50_1282"
     CDS             6612..7556
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="C1A50_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1282"
                     /product="YitT family protein"
                     /protein_id="WP_013369852.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKVKRLLQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISDKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFIAIGNIHDVKGGRFKKKGIH"
     gene            complement(7625..8527)
                     /gene="ligD"
                     /locus_tag="C1A50_RS05985"
                     /old_locus_tag="C1A50_1283"
     CDS             complement(7625..8527)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="C1A50_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1283"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_017426476.1"
                     /transl_table=11
                     /translation="MGRAVKGTITIEGHEIAITNPDKPLWPEAGVTKALYLRKLAVLAP
                     YLLKYCHQRLLTVIRWPHGIHGDFFYQKNAPHPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHRTGSQLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPNLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDLLKHMRSKTHPT"
     misc_feature    complement(8676..8689)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     gene            8740..10026
                     /locus_tag="C1A50_RS05990"
                     /old_locus_tag="C1A50_1284"
     CDS             8740..10026
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426477.1"
                     /locus_tag="C1A50_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1284"
                     /product="sulfotransferase"
                     /protein_id="WP_025364271.1"
                     /transl_table=11
                     /translation="MIEKQGGKLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSHARPYGGTGILRQFFKGMVPPHVLEQAARSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFVDRLFPAARRVWLIRNPLSIVASFKKVNQLRNGNFHLLKELGSPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLMYEQLVANPRMEIEKLCHFLEIHYEPGMERYGNFAD
                     TPQSNLFYSMGAGDPFVMEHEQAHQNSVHSWQYLLSTMEIELYCRSIGARLFRQLGYGE
                     ALEQAEQLTGVRFEDDPDVELLSRRTHQFLQQSGFEWKAAYRMLEEQDADNKVFMTNAT
                     CHAAPHNPARMDMAQIVSDRRIQSLENRLAHSFEERNRLIAQLQSYQRPSQGFRSHLLA
                     RKFGRWASEVLSSIGKEKGGERECNCRNL"
     gene            10001..11926
                     /locus_tag="C1A50_RS05995"
                     /old_locus_tag="C1A50_1285"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="C1A50_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1285"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_025364272.1"
                     /sec_met_domain="GATase_7 (E-value: 1.2e-19, bitscore:
                     68.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 8.1e-25, bitscore:
                     86.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYRFGHESVYAEEGEKMMQTLQKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLAVEQGRRIDITDSELI
                     LLAYDKWGVDAAGYLIGDFAFVIWDAKKHRLYGARDMTGNRTLYTYQHDGGFAFSTVVA
                     PLLVLSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKQSLC
                     KYACLDEVEPLRLKTGGEYIEAFREVFSQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PSLHLQHKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIRENYMDFEGKSP
                     FSEIDMWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSWQGVRRYSKLTGSRMSHLLPVMLKKATSLDARTWWGRGKQSPIPSLIH
                     PEFAKRMNVEDIPVLSGTGWRKNADQTRKEKFSNLAIANKNGVMATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRKAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQVMCHDLRAAEYLNMDYIKTAMAKYRHPRPDQASDPNIRLFMHSLIVYR
                     FLCGLN"
     gene            11980..12108
                     /locus_tag="C1A50_RS25040"
                     /old_locus_tag="C1A50_1286"
     CDS             11980..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="C1A50_RS25040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1286"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_013369856.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLYNPS"
     gene            12237..13292
                     /locus_tag="C1A50_RS06000"
                     /old_locus_tag="C1A50_1287"
     CDS             12237..13292
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821222.1"
                     /locus_tag="C1A50_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1287"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_045244075.1"
                     /transl_table=11
                     /translation="MSPIAHDRSAHNSWVKYTAFGLRIASELTLPELIPAEPGLVEDVV
                     IRQVDLSAWRDQLEQANFVMQGERFMFLMPDTAIYAIRGGKEIEVSMLPGADPDTVRLF
                     VLGTCMGVLLLQKRVLPIHGSAVVIGGRVYAFVGESGTGKSTLAAAFRQAGYQMISDDV
                     IAINVTASAAIVYPAYPQQKLGLESLLQLEALRENKHVRQRKHVLSLTDGNPVRAQYQD
                     LRRIAGELNKYAVPAVDEFYNDPLPLSGVFELVSDSPNRESMREGEPVVVTEQPLNKLE
                     CLHTLLQHTYRRAIISRMGLGEWYFDTAARMARKVEGWRLLRDSSFFTASEVVQRVLEL
                     IHKEEKSYGSH"
     gene            13279..13581
                     /locus_tag="C1A50_RS06005"
                     /old_locus_tag="C1A50_1288"
     CDS             13279..13581
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369858.1"
                     /locus_tag="C1A50_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1288"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_017426480.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-24,
                     bitscore: 84.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.3e-16, bitscore: 58.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAINPAKDHYRITYGEEVYVSDMDGEKVMMSIHTGKYYNLGFTG
                     GRIWELAEFSPSIEDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLRLLRELD"
     aSDomain        13327..13560
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1A50_RS06005_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.10E-27"
                     /identifier="RREFam002.1"
                     /label="C1A50_RS06005"
                     /locus_tag="C1A50_RS06005"
                     /protein_end="94"
                     /protein_start="16"
                     /score="84.3"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSIHTGKYYNLGFTGGRIWELAEFSPSIEDI
                     VTVLTNEYEVDEEQCRQQVHTFVAELEREGLLR"
     gene            13583..14068
                     /locus_tag="C1A50_RS06010"
                     /old_locus_tag="C1A50_1289"
     CDS             13583..14068
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="C1A50_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1289"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_025364274.1"
                     /sec_met_domain="PF13471 (E-value: 6.5e-24, bitscore: 82.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRRLLPEAWLELGCARFRQRRSFGDYSGAWGTC
                     MEETSWQCEVGQEKSIRHISQAVDVASRYTPWRSSCLVQAAAAMTLLVRRKLDCTLYLG
                     TAKNAAGQLAAHAWVRSGPIYVTGEREMGAFTVVGIFGRRAGTATNTRTADKGSSLF"
     gene            14126..15652
                     /locus_tag="C1A50_RS06015"
                     /old_locus_tag="C1A50_1290"
     CDS             14126..15652
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="C1A50_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1290"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_103042269.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.6e-83, bitscore:
                     277.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKSILELANWNEDQELTLLLSLLRKDVNLWQNTMTAFQLQEID
                     WSRLLRLTEHHRVIPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLTAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMKEAGYASKS
                     GEVRVLGSWKWKDHHASFLHPQKRVEVELHWRLHPDGGREPSFDELWDCRQMGKAPAVR
                     ASQMAPATSADSRNVTTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVRAVD
                     WRALLPQMRRYGGLPAGGQAWALAAALFGTPIPEPMRPISATRQAHRLALSALAFMQAS
                     VPAPYPVANGAGTGRLVRPELLPNVALTESMNTAPSDGGISANGTSGEAVLYAVSSDAG
                     ISKDASSILGDPVNTVNTAVSSLAKPVGAATVASSPAIAGATTTAFTPQPVSRAYLLSL
                     KEPRHRLWYLISRLFPSTRDSVICPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15673..17532
                     /locus_tag="C1A50_RS06020"
                     /old_locus_tag="C1A50_1291"
     CDS             15673..17532
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="C1A50_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1291"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_103042270.1"
                     /transl_table=11
                     /translation="MTHLRLYMTKLYSLNGGALFLNIGCMMIVSLLEGVGIYMLVPMLA
                     AIGVFGGHSEMPFLSDGFDYFLPYIPKSWLLPGMLMFFVMLLTGQAWLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLVLFVVFRRSIRNAKQLGDRTTELSQIYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRIAAAVFVVSVLFVS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQRECEAFSDPS
                     LIGLTSSENHVPFDSSVNHLSSTSARQPLSLRNGIECSHLDYCYEGAAVPALRHINLLI
                     PARGMTAIVGKSGAGKSTMVDVLMGFLRPTGGQIKIDDHVLDDKLLPLWRQSFGYVSQD
                     PFLFHATVRENLKLADKDASEQQLWEALHFAAADNFVSRLPEGLDTVIGDRGIRLSGGE
                     RQRLVLARAILHHPPVLILDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRH
                     ADQIVVLDQGEVIQQGNYHQLVEEERGAFSQLLSYQSTVSAAP"
     misc_feature    17568..17581
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    17960..17975
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
     gene            18192..19523
                     /locus_tag="C1A50_RS06030"
                     /old_locus_tag="C1A50_1293"
     CDS             18192..19523
                     /EC_number="3.1.1.-"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728406.1"
                     /locus_tag="C1A50_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1293"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_103042272.1"
                     /transl_table=11
                     /translation="MKKKMIIALGASAIMLANFVGSTYADSKTVVPVTAPYNTNQIAEW
                     LEAHAKPLKTTNPTAPLNDLKPLKNMVGSASIVGLGEATHGAHEVYTMKHRIVNYLVSE
                     KGFTNLVLEEGWDRALELDRYVLTGKGNPSQHLSPAFKTKEMLHLLSWIRQYNANPKHK
                     SKVRVIGMDIQSVNEDVYNNIVEYIKRNNSDLVPRVEKKIRGLIPVTKDMDTFGSLTQK
                     EKEKYISDAKQISALLEQNKSYLNGKSREFAWIKQNARIIEQFTTMLASPPDKPSDLFL
                     KHDIAMYENAKWTEEHLGKTIVWGHNGHVSKTNMIPFIYPKVAGQHLAEYYGERYVSIG
                     TSVYEGQYNVYNNDGEFGPYGTLKSDDPNSYNYIFGHVKKDQFIIDLRKTNGVTKTWLN
                     QQHPIFAGITTEGPNIPKTVDISLGKSFDILVQIQKVSPSQLHQ"
     gene            complement(19711..20625)
                     /locus_tag="C1A50_RS06035"
                     /old_locus_tag="C1A50_1294"
     CDS             complement(19711..20625)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="C1A50_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1294"
                     /product="Ku protein"
                     /protein_id="WP_019686435.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVKPVVTDPGPAAKKRPARKPAAVTAQQA
                     VAGDAISPAPVKKKRSPAKRKET"
     gene            20835..21074
                     /locus_tag="C1A50_RS06040"
                     /old_locus_tag="C1A50_1295"
     CDS             20835..21074
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="C1A50_RS06040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1295"
                     /product="hypothetical protein"
                     /protein_id="WP_013369863.1"
                     /transl_table=11
                     /translation="MPRKPYPQQISHRVGQSHIAFRGPAGGEQDALPPEFALSHGTPPP
                     FPVAVAHVDMEAVVSTSPSHSFPSLDVERIIDED"
     misc_feature    complement(20876..20888)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            21126..21305
                     /locus_tag="C1A50_RS06045"
                     /old_locus_tag="C1A50_1296"
     CDS             21126..21305
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="C1A50_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1296"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_013369864.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSETIAVQLDGKPIWIEHVDEANGMATVQIGSRP
                     GDTQTVRVDRLEEQ"
     gene            complement(21438..22094)
                     /locus_tag="C1A50_RS06050"
                     /old_locus_tag="C1A50_1297"
     CDS             complement(21438..22094)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="C1A50_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1297"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_102998566.1"
                     /transl_table=11
                     /translation="MNNRELIIRRIAQEFKDGEVVNLGIGLPTMAVDYIPENINIMLQA
                     ENGIVGVGPKAAPGKERLDCIDSGGNYVTTVKGACFIDSALSFSIIRGGHVDVTVLGAL
                     EVDEKGNLANWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKGVIDVIPGKGLMLKEIAPGLSVEDVQMATEAELMVSPHLKTIAV"
     gene            complement(22087..22755)
                     /locus_tag="C1A50_RS06055"
                     /old_locus_tag="C1A50_1298"
     CDS             complement(22087..22755)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426488.1"
                     /locus_tag="C1A50_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1298"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_103042273.1"
                     /transl_table=11
                     /translation="MNKKVNSDEEAVKKIKDGDTVMVGGFMQGGIPEELVRALVDTNSA
                     DNLTIISNDTGTTELSIYRLVKSGRVKRIFASYIGSNPETGRLLMTKEADVQLFPQGTL
                     AEKIRAGGAGLGGILTPVGVGTIVEEGKKKIKIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNLVMATAAEYVVAQTDEYVKAGEIDPNHINVPGIFVDAIVKVGGDNE
                     "
     gene            complement(22793..23533)
                     /locus_tag="C1A50_RS06060"
                     /old_locus_tag="C1A50_1299"
     CDS             complement(22793..23533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="C1A50_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1299"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_031463089.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTYNGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEDTETLTGTLHYNNALVAMGTTPFKYNVLDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLEDITVKGAWSGPARLSLIPHVNAPVADLPVRA
                     YVGGKHFIADLTLPYGRVLYDYLQ"
     misc_feature    complement(23862..23878)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.35"
                     /tool="antismash"
ORIGIN
        1 attacggtca ctcagcacta caagacccga ttcggtactt ttgatatcgt acagccttgt
       61 tatgtgacgc aggaagatga ggagtggaga gtgctttgga tatacaagga gaaggaacag
      121 acgtgataag gtgctcccaa aggtgtttct gacaggataa atatggtaca atacttccaa
      181 aaccggaaat gtacagtaaa ttggatgaca gcttcactcc gggtggaagg agtttcatag
      241 catgcagcaa gcgacagggc aggttcccgt catacggatg gagggtgtga gtaaaatcat
      301 ttcctcaaaa gcgatcgtgg acaatctgac actggaggtt ccggcaggac aggtatttgg
      361 tttcctcgga ccgaacggtg caggaaaaac gaccaccatt cgtatgatgg ttggcctgat
      421 ttcgatcagc aagggtgata ttcatatttg cggagacagc attaataccg atttcgaaaa
      481 ggctgtttcc catgtcggtg cgattgttga gaacccggag atgtacaagt ttttgacagg
      541 ctatcaaaat ttgcagcatt ttgcgcgcat gtcgcctggg gtgacccaag aacgtataga
      601 tgaagcgatt cgtctggtgg gactcggaaa ccgaattcat gataaagtca aaacctactc
      661 gctcgggatg cgtcagcgac tcggggtagc tcaggcgatt ttgcatcgac cgaagctgct
      721 cgtgctggat gagccgacca atggcttgga cccgcagggt attcgtgaac tgcgggatta
      781 tttgcgtcaa ttgacccgta ccgaaggaat taccgtgttt gtatcaagcc atttgttgtc
      841 cgaaatggag ctgatgtgcg atcgcgtggc cattattcag agcgggcgat tggttgatat
      901 taagcagttg aagaatacag agggagaagt gcagacggcg gaaattgctt ttgaagtcaa
      961 tgatgctgag caagcttata cgcttgctgg agcagggcgc gtcgaaggca atcaactact
     1021 gcttcacctg gagcgggaac agattgcaga gatgaacagt ctgctggttg caaatggagt
     1081 caaggtgtat gcgattcgcc cggttgcccg tacgttggaa gatcaatttt tggaagtgac
     1141 gggaggcggg tccattggct gatttcttca agctggtaca taatgaaaat cttaaaatct
     1201 acttgcgtgt gcgcacatgg atcatgctgg ggctgctggc ggtcatcacc gctgtgattc
     1261 cgatgctgat ttctctagtt tctgatcagg ttagtgtgtg ggatggcatc gcattgacaa
     1321 cgttgtttac atttttcctc aatacgacgt ttacggtcat tgtagctgct gattcggtgg
     1381 ctggcgaatt tacatgggga acgattaagt tgctgctcat ccgtccttgg actcgcagca
     1441 aaattttgtt gtccaagtat atatcggtga ttttgttcag cttgcttgga acaatcgttt
     1501 tggtcttgat ggttacgctg tcctcctggc tgatgttatc taaggacgca ccagcgggct
     1561 ctgttccgct gttcagtgat ccgatatctt acgaaacgct gaactttttg tatagctata
     1621 tcgccttatt cgtgaccatg gcttttgcat ttatgttatc cgcggtgttt cgttcgagcg
     1681 ccttggcgat tggtttgtcc ttgtttatga tgttcaccaa aacgatttat aactctattg
     1741 gcttgttcag cacagatcgt tttgaatgga ccaaatacgt actctttacg catatggatc
     1801 tgaaaaaata tctagatatg ccgccgggta cagtaagttc caatctaacc ttttcgctcg
     1861 ccgtgctggc cgcttattat gtggttttta tcgcgattgc ctgggtggtt ttcgtaaaac
     1921 gcgatgtctc cacctaaaca cgtatctctt agcatgtgtg attgaatgac acgaggattt
     1981 tggcaaaatg ctgagatcac aaaaaggaag tccaatgcct agccatttgg acttcctttt
     2041 ttgctatgtt ggcactgttt tattcagtat ctatgtcatt tttgctacat attctgtaag
     2101 tgtgggtata ttgtaatcta ttttcagcaa gaatcaatca atagggtcgg tttgcgttta
     2161 aagaagtaga gagaaacaga acaggggggc gtatgatatg ctgcaaaata atcgtttttt
     2221 tcgcctgact tcaggaatcg tcatgctatt gctcatcatt tacttgggca ccaaagtaag
     2281 ctttatattc agtcctcttg tatccttggt cagcttgctg gttgtaccgt tgatgctatc
     2341 ttttttcctc tattatttat tgagaccgat tgtagatgtc atggaacgga gaaaaatcaa
     2401 acgatcgatt tccatattgc tgatttattt ggttattggc gtgttactgt tcctcttctc
     2461 atggggagtg tggcctacgc tccgtgatca ggtaaccaat ttatttgaga acgcgccgaa
     2521 gcttattaaa agtctggttg atcaattgag ccaatggcgg cataatcaat ccttgagaca
     2581 agtactgcct ccgggtgaag acccgctgtc acaactgtca gatacgttaa acgaagcttt
     2641 ttcaacgctg tcagattact cggtaaagtt ggtatcgttc gtatcctact tttttatcgt
     2701 attggctacc tttcccatat tgctctatta catgttgaag gaagggagca agtttggtcc
     2761 caaaatgctt aacttctttc ctaaaaagta tcataaggac gcgctggaag ttatggagga
     2821 tattgatagt gcgctcagca gctttatcgt cagtcgagtg ctgatcaatg tcgcgttggg
     2881 cttgatgatg ttccttggat ttttgattat tggtttgcct tatgccttgc tgcttgccgt
     2941 tatttcgatt ttccttaatt ttattcccta tgtgggggca gtagctgctt ctatacctgt
     3001 ggttatcatt ggatttctcg aatcgccttc catggcgctc tggtcgctgg tggtggtgat
     3061 cgttgcacag caaattcagg ataattggct gtcgccgatt gtctttggca agcagctgga
     3121 cattcatccg ttgactgtcg tcattttatt gctagttggt ggcgacctgc tcgggatctt
     3181 gggtatcatt ttggttattc cattatatat gtgcggcaaa atcgtcatac gcaaggtgta
     3241 ccatttattt ttggaacgca gagtggagga tattatggag tgattggagg atgtactgga
     3301 tatataggag tataagccgg ccctatcccg cttcaggttg tagggaggct tggctgtcct
     3361 ctatgtcttg gctgaaactg gattgatttt catcctctga tttctctata gcagctggcg
     3421 actctgcatc catagtttgg ttcatttgac ttgtgccgtt cagtacgccg ccttcagaaa
     3481 tgaccaatgt aggggtcgcc gtatttccgt acagttcgcc tgtcgatgta atggtcagcc
     3541 gtccttctgt ggtgatgctg ccgaatacct tgccggcaag aatgacgtcc cgtgcaataa
     3601 tgtccgaacg tacaactgct gattctccaa tgacgacagt gcgagtgctg tagatatcgc
     3661 cctgaaaatg accgtcaatg cgaatgttgg cctctgcctc aatcgtacct tcaaagctgg
     3721 tgccgttcgc gagcagtgta tccgtcgtcg ccggggtgga gagctttttt ttggattcct
     3781 tgaacatgat cgttttcctc caatccttta ttgtcggtat tttgcaaaac ccttattgta
     3841 catacagcaa tggatcaaca ggttggttat gcttgacgat ctgaaaatga agatgaggtc
     3901 ctgtgcttct cccggtactt cccagcaggc caatggtctg tcctttgtga acacggtccc
     3961 ccggagccac ctgcataccg cttaggtgca tataccagct ttggagtccg tctggatgct
     4021 gaatgatgat gcacttgccg cgagctccgc tggaagcggc ctccagcaca gtgcctgccc
     4081 ctgctgcata gacaggatca ccggattgac cggcaatgtc cacgcctgag tgaaaagcgg
     4141 atttccctgt aaatgggtcg ctgcgatagc cgaaactgga ggtcatgcgc cgcgaaccaa
     4201 caggccaaat ggagggcttg ccttgttcag caagtgccag tcttcgggtc tggagcagct
     4261 gcgcggcttg ttggcgctcc aggttctgct gtacggcgtt tgcctgttga atagagcgcg
     4321 gaaccgtgcg ctccactgtg tccagcagag cttcgatttc ctgaaaatca tccatggcct
     4381 ggcgggctag aagagctgta ttttcatgca ctgcgatcaa ttcaccgccg gtatggccgg
     4441 aagcatccca ggagaggggg gtgatggttg atttattact gcttgcgctg gaggaatttc
     4501 cgtgtttacg aatgaattgc tgcatttgtt gttccagctc agttacacgc tggagacgtt
     4561 cgcgaatact ggtggcttga ttcgtcagct ccatgacttc ctgccgcagt cgcccaatgg
     4621 ctgcgtcttt gtctgctacc gtaacctcca tctgcaaact ctggacagca agattggttt
     4681 ccatttggga aataatatgg gaagaacgga tttgcagccc gatcacgagc gtagagattg
     4741 atgcgatcac aagggtcggg acgagaatga cagcggctgc ggagcattgt agctgcttgg
     4801 gcggttgctg tgcatcccga atgacaagca gggtcatccg gcgatttagg cttccttttt
     4861 tcataatcgc tcctttccgg acatcgctcc tatagtgctt ggttactatc tattcagctt
     4921 aagaggcaaa catgtcaaaa aaattggagc tttgtataaa acgtagatat ataaggaggc
     4981 ttagacatgc tgtggttgct gttggtttta attattttta tttttcagac cgggacgatt
     5041 ctgctctttg aatttcgcaa gccgtccaaa gcggtagcct ggctctttat tttgttttgc
     5101 ttcccgctta ttggttttgt ggtgtactat tttgttgctc aggattacca gaagcgtaaa
     5161 gtggttcgta aagcaggatc gcagctattt cgtgaattcc gtgaacatct gtgggcgcaa
     5221 accaaggtga ttgaaaatgt agagcaaatg cacaatcccc atttcaagca tcaggagcgt
     5281 ctgtttaacc agttaattcg tatgtcggaa aacccgttga ctggctgcaa ccgtacacgt
     5341 gtgctgacga acggggaaga gactttcgac gccatgctga aagcgatgga acaggcacaa
     5401 catcatatcc atgtggagtt ttacatattt cgggcagacg aaatcggaaa aaaatttcag
     5461 gaggtcatga tccgtaaggc acgcgaggga gttaaggtac gattcattgt ggacggcgta
     5521 gggagctacc atttacccta ttcgtttatt cgcacttgta atgaggctgg gatcgaattt
     5581 cattattttc taccgccgtt tttcgccacg ctggaccgcc ggattaacta tcgcaatcac
     5641 cggaaaatcg tggtggtgga tggcacgatc ggatttgtgg ggggaatcaa tgtaggcgac
     5701 gattatctcg gaaagtaccc caaagtggga ttttggaggg atacgcattt gcagattgaa
     5761 ggagatggcg tttattttct gcaaaatgtg tttcttagcg attggaagct ggcttcgggg
     5821 gagaggctaa tggacgtgaa tttatttcct ccacatacct gcacagggga tgaggaagta
     5881 cagattttga gcagtgggcc cgatcaggta tgggatacga ttcaggaatt gtgctttgga
     5941 gcgcttacgg ttgccaaaaa gcggatttgg ataacgacgc cgtattttat tcccgatccg
     6001 gggatttatg aggcactgaa gctggcggcc gtcagcggca tagatgtgaa aattattatt
     6061 ccctaccaat cagattcgaa actggtacac ctggcgtcac tgtcctatgt gcaagaactg
     6121 ctggaggcag gagtggagtt ctaccaatat cgaaaaggat ttattcacgc taaagtggtg
     6181 attgtggacg atttgctcgg ctcggttggg accgccaata tggacatgcg tagctttttc
     6241 tataattttg agttgaccgc tgtacttttt gcaacttcgg cgttggaacg gctttcggca
     6301 gattttgtag aggacatttc caactcttcc aaaatagatt tgaacgtgtt ccgcagacgc
     6361 cctcgatctc aaaaaatagc tgaaattcta actcgcatgc tctctcccct cctttagagc
     6421 cggttttcgc cgtttttatc aatataatcc cgctttattg tgatttatgt gctctttgct
     6481 aacttttttg cgcaaaatca cagttttatg atatactaat cacataacta agcgccgtaa
     6541 aggagagggg actgcggaga gcagcccctt tttcggtcca atataccata ctgtaacggg
     6601 gggatttata tatgagtgta gtgagcaagg aagtccaaaa tctgtctgag atcacagatg
     6661 taaccggaga gttgaccaag atcagcaaaa ttccagctaa tccaaagaac aaagtaaaac
     6721 gcttattgca gcgtgcagcc atgatcgtgg ttggtgcagc gctgatggcc gtgggattgg
     6781 aaatattcct agttcctaac ggcgttattg acggcggcgt tacaggtatt tccattatgg
     6841 cctccaagat tactggttat ccgctcggta ttttcctgac cctgttgaac cttccatttt
     6901 tacttatcgg ctacaaacaa atcggtaaaa ccttcgcttt atccacatta ttcggcatcg
     6961 tcgttatgtc catcggaact gcgttacttc acaatgtaag tgcattgacg cctggggaac
     7021 cgctgcttgg cgctatcttc gggggtgtca ttctcggcgt gggagtgggt cttgtgattc
     7081 ggtccggcgg ctcgctggat gggacagaga tcgtggctat tctcgtcagc gaaaaaactc
     7141 ctttttcggt cggtgagatc gtattgttcg ttaatatttt cattctggga agtgcgggtt
     7201 ttgtattcgg ttggccgaat gccctgtatt ccatgattgc ttattatatt gctatgaaaa
     7261 tgattgatat tacaattgag ggtctggatc agtccaaatc ggtctggatt attagtgata
     7321 aataccgtga tatcggagat gccctgacgg accgtcttgg acggggggta acttacctgg
     7381 aaggtgaagg cggctttaca ggcgagagca aaaaagtgat tttcgtcgtc attacccgac
     7441 tggaggaagc gaagctcaag agcatcgttg aggattggga cccgcacgcc ttcattgcaa
     7501 ttggtaatat tcacgatgtg aagggcggac gttttaagaa aaaaggaata cactagcgca
     7561 aggggacaat ttctcagcct atggctgcgg ggttcgtccc cttttttgtg cttcaaagca
     7621 tggatcaggt tgggtgtgtt ttggagcgca tatgtttgag gaggtcctct acgggctggg
     7681 gaggcacctt gtcgatcaag tcgcctacct ggtttaaccg ttcctcaata tttagtaaat
     7741 ggtaatcaag tggtgacaca tcttgccgta cctcttccca ggttagcgga gtcgagaccg
     7801 tagcaccggg acgtgcccga ggagtataag gagcggctag ggtttttccc tgataatgct
     7861 gcaagtaatc aaaatagatg gctgttccac gatccttctt taaccgttcc agtgtgaaca
     7921 gattcgggtg cttttccgtc acaaattgtc caaccaacag tccgatgctg cgtagctcgt
     7981 caaaggtgat gcctgtacgg atcgggacga taatttgtac acctgtggcc ccggaggttt
     8041 tggggacaga gtccaacccc agcgaagcca atacttcgcc tacaatggag gcggcctcca
     8101 taatacgtgg ctcgacttct ctggatggat ccagatcaat catccattca cagggcagtt
     8161 ggcttcctgt tctgtgcaga gagggatgaa attccaacgc agcttgatta ccgagccaga
     8221 gtagttgggg cagcttgcca agcacgatat actcaatgcc atcatgcaga gcggtttcaa
     8281 tatagtctgg ccgaggatgt ggggcatttt tctgataaaa aaaatctcca tggataccat
     8341 gtggccaacg gatgacagtc aatagacgct gatgacaata tttgagcagg tagggggcca
     8401 ataccgcaag cttgcgaaga tatagcgcct tagttacacc tgcttcgggc cacagcggtt
     8461 tatccgggtt tgtgattgca atttcatgac cttcaatcgt aatcgtacct ttaacagctc
     8521 gtcccatagt gctatgctcc tttggttaac atgcagcaag atcattattt acagacaact
     8581 ggcagcattt ctacatctac ataaggttta acatgagcgt gcagcacaga atttatccat
     8641 caaagggatt gacaagatac attatgtatc ataaattata ataaaaatac gatatgtatc
     8701 tattaaaacg tcttgagcag aggtagagga ggagtgtgct tgattgaaaa gcagggcgga
     8761 aagctagtat ttctgttgag tgtccctcga agtggaagct cgctgctaac cgccattttg
     8821 caaaaccatt cccgtctgtt tgccacgcag gaaatgtggt ttctgctcag tttatatgat
     8881 cttcctcagt cacatgcacg gccatatgga ggaacaggaa tactccggca attttttaaa
     8941 ggtatggtcc ctccacatgt attggagcag gccgctcgtt cgtatgcact tgaaatatat
     9001 aatggcctgc ttcaggggac gaccgctgat atgcttatcg acaaatcacc gcgttactat
     9061 acagtgcttg aatttgtaga ccgtttgttc ccggctgccc gtcgagtgtg gcttatccgc
     9121 aatcctttgt ccatcgtggc ctcgtttaaa aaggtcaatc agctccgaaa tgggaacttt
     9181 cacctgctga aggaactggg aagtccgcat tttaatatga aaatgacaga tattacggtt
     9241 ggtttgttcc ggtacgctca ttattttgcc acacctcatc cacttgcata cccgctgatg
     9301 tatgaacagc tcgtagccaa tccaaggatg gagattgaga agctgtgtca ttttctggag
     9361 atccattatg agccggggat ggaaaggtac gggaactttg cggatacgcc ccaatccaat
     9421 cttttttata gcatgggagc gggtgatccg tttgtcatgg agcatgaaca ggcgcatcag
     9481 aattcggtac atagttggca atatctattg agtacaatgg aaattgaact gtattgcaga
     9541 agtattggag ctcgcttgtt taggcagctt ggttacggag aagcgctgga acaggctgag
     9601 cagttgacgg gagtccgctt tgaggatgac ccggatgtag agctgttgag tcgacgtaca
     9661 caccagttcc tccaacaaag tggctttgaa tggaaggcag cttatcggat gctggaagaa
     9721 caggatgcag ataacaaagt attcatgaca aatgcaacct gtcatgctgc acctcacaac
     9781 ccggcaagga tggatatggc acagatcgtg agtgatcgac gaattcaatc actggaaaac
     9841 agactggcac atagctttga ggaacggaac cggctgatcg cgcagctcca aagctatcag
     9901 cgcccaagcc aaggattccg gtcccattta ttggcccgta agttcgggcg ctgggcgtct
     9961 gaagtattat caagtatcgg aaaagaaaag gggggagaac gtgagtgcaa ttgccggaat
    10021 ctatagattt gggcatgagt ctgtatatgc tgaagaaggc gaaaaaatga tgcaaactct
    10081 gcaaaaatat cccgctgacc gcgtgtgcgc ttggtgtgaa ggttccattt ttttgggatg
    10141 tcatgcccag catgtgaccc cagaatctgt tcatgagcgt cttccctttt atgatgagct
    10201 aagagatttg gctataacgg ccgatgcgat cattgacaac cgttctgagc tgtttgaacg
    10261 actagcagtt gagcaggggc ggcggataga tatcacggac agcgagctga ttttactggc
    10321 atacgacaaa tggggtgttg atgcagcagg ttatctgata ggtgattttg cctttgtcat
    10381 ttgggatgct aagaaacatc ggttatatgg tgctagagat atgacaggca atcgtacgct
    10441 gtacacctac caacatgacg gaggatttgc gtttagcacg gtagtcgctc cgctattggt
    10501 tctgtcctct ctgcgaaaag aactgcatga accatggctg gccgaattct tatctatccg
    10561 tgcaatgcag gaatccgtcg atatcgggac aaccgcctac aagcatatca accaactgcc
    10621 tcctgcacat tggttcacta tggaagaggg aaagcaatcg ctctgtaaat atgcatgtct
    10681 ggatgaggta gagccgttgc ggctcaaaac aggcggcgaa tacatagaag ctttccgtga
    10741 ggtattctcc caggcggtaa ctgcccgatt acggacgcat cgcgctgtag gggctgccct
    10801 gagtggggga ttggattccg gagcggttgc cagctttgcc gcgccatcgc tgcacttaca
    10861 acacaagccg ctacatgcct acagctatgt acctgttcaa gattttacag attggacacc
    10921 gcctacattg ctggcaaatg aacgcagcta tattcagtcc accgctcgct atgtgggcaa
    10981 cattcgtgaa aattatatgg attttgaggg gaaaagtccg ttttctgaaa ttgatatgtg
    11041 gctggagttg atggaggctc cctacaaata ttttgaaaac tccttctgga ttagaggttt
    11101 ttatgagaaa gcacaggaac ataatgtcgg agttctgttg actggggcac ggggcaattt
    11161 taccgtatcg tgggggcctg cactggacta ttatgcccgt cagtttcgcc gtttgcattg
    11221 gctgcaatct tggcagggag tgaggcggta tagcaagctt acaggcagtc gtatgtctca
    11281 tttactgccc gtgatgttga aaaaagccac ctcacttgac gctcgcacat ggtggggacg
    11341 tggcaagcaa agtccgattc cttcactgat tcacccggag tttgccaagc ggatgaatgt
    11401 agaagatatt cccgtattga gtggaactgg ctggagaaaa aatgccgatc agacaagaaa
    11461 agagaagttt tcaaatttgg cgattgccaa caaaaatggt gtcatggcga ccaaactttc
    11521 actccgttat ggcctgtggg aacgtgatcc gaccggggac agccgtgtca ttcgcttttg
    11581 cttatcggta ccttttgaac aatatgtaca aaatggccgg gaccgtgccc tcattcgtaa
    11641 agctatgcgt gatcatctcc ccgatgatgt tcggttgaac cagcgagtac gcggcgtaca
    11701 gcctgcggat tggctacatc gtatgcttcc ttgctgggac acgtttatgg gagagctgca
    11761 agtgatgtgt catgatttac gagctgccga atatctcaat atggactaca ttaagacggc
    11821 tatggcgaaa taccgacatc cccgtccgga ccaggcatcc gatccgaata tacgactatt
    11881 catgcacagc ctgatcgtgt accgttttct ctgtggtttg aactgatttg gatctaaccg
    11941 atcagacggc gtgccattcg tgggagggga ggtgatgaga tgagtaaaaa agaatggcag
    12001 gaaccgacga ttgaggtgct ggatattaac cagactatgg cgggtaaagg ctggaaacag
    12061 attgattggg tgtcagacca tgatgccgat ctgtataatc cgagctaacg gaagataatt
    12121 atacatgagc cgatgttggg ctgagatcca aatagcttac tgatcatgag ccgtctttat
    12181 ttcattcggg ttaggttgga ccggaagaaa taaagacgga attttaagaa cagggagtga
    12241 gtcctatcgc gcatgacagg agtgcccata acagttgggt gaaatataca gcctttggac
    12301 tcaggattgc cagtgagctg actctgcctg agctgatccc agcagaaccg ggattggtag
    12361 aggatgtggt catccggcag gttgatttgt cagcatggag ggaccaactg gagcaggcca
    12421 attttgtaat gcagggtgaa cgctttatgt tcctaatgcc ggacacggcc atttatgcca
    12481 tcaggggagg caaggaaatc gaggtaagta tgttgcctgg ggctgatcct gacaccgtgc
    12541 ggttgtttgt actgggcaca tgcatgggtg ttctactgtt gcaaaaacgg gttttaccta
    12601 ttcacggaag tgcggtcgtc atcggaggtc gggtctatgc atttgtaggt gaatccggca
    12661 cgggaaaatc gacgctggct gctgccttta gacaggctgg ctatcagatg atcagtgatg
    12721 atgtgattgc tataaacgtg acagcttccg cagccatcgt atatccggca tatccgcagc
    12781 agaagctggg actggaaagc ttgcttcaat tggaggcatt acgggagaac aagcatgtac
    12841 ggcaaagaaa gcatgttctt tccctaactg acggtaatcc tgtaagggca caataccaag
    12901 atttgcgtag gattgcaggt gagctcaata aatatgccgt gcctgctgtg gacgaatttt
    12961 ataacgatcc gcttcccctg agcggtgtat tcgagcttgt gagcgattct cccaaccgtg
    13021 agtcgatgcg tgaaggggag ccagtggtgg ttacggaaca gcccttgaac aaactggagt
    13081 gcttgcatac attactacag catacatatc gtagggcgat catttcgcga atgggtttgg
    13141 gtgaatggta ttttgataca gcggcccgga tggctcggaa agtggaaggc tggcggctgc
    13201 tgagggatag ctcctttttt acggcgtccg aggttgtaca acgcgtactt gaactcattc
    13261 ataaggagga aaagagttat ggcagccatt aatccagcta aggatcatta tcgcatcacg
    13321 tatggtgaag aggtctatgt aagtgatatg gacggagaaa aagtgatgat gagtattcat
    13381 acgggaaagt attataattt gggcttcaca ggaggacgga tttgggaatt ggcagaattc
    13441 agcccttcaa ttgaagatat tgtaactgtc ctgacgaatg aatatgaagt ggacgaggaa
    13501 cagtgcagac agcaggtgca tacctttgta gctgaattgg agcgggaagg attgctgagg
    13561 ctcctacggg agttggacta acatgcggat acaacggctt cttctcttgt ctccagaggt
    13621 caggagattg ttgccggaag cctggctgga gctgggatgc gcgagatttc gccagcgtcg
    13681 ttcttttgga gattactcag gggcttgggg gacatgtatg gaagaaactt cttggcagtg
    13741 cgaggtcggg caggagaagt ctatccgtca catttcacaa gctgtggatg tagccagccg
    13801 ttatactcct tggcgcagta gctgtcttgt acaagccgct gccgctatga cgttgctggt
    13861 acgcagaaaa ctggactgta cactgtatct gggcacagcc aaaaatgctg cgggacaatt
    13921 ggcagcacat gcatgggtac ggagtgggcc gatctatgtt acgggagaac gggagatggg
    13981 agcgtttacc gtggtgggaa tattcgggag acgtgctggg acagctacaa atacgaggac
    14041 agcggataaa ggcagttctc tgttttagtt ttagtgcgat ataaaaggaa caaagaacgt
    14101 tcaaagaatc gaaggagaag aatccatgac caccaagtct attttggaac ttgcgaattg
    14161 gaatgaggat caagaattaa cgttgttact ctctctactt cgtaaagacg tcaatctatg
    14221 gcagaatacg atgactgctt tccagttgca ggagatcgat tggtcccgct tgctgcgtct
    14281 gacagaacac catcgtgtga tacctacggt gtatctccag ctgaaaacgt tgaatcaccc
    14341 gttcattccc gcagaattgc tgcgaaacct tcaggcgcaa tatcatcgaa acacgctgcg
    14401 catgctccat cttcaagcag aagccgagcg tctgaccagg ctgctcacag ctcatggaat
    14461 tcgtgtgctg atgttgaagg gtcctgctct ggcgcagcaa ttgtacgggg atgtttccct
    14521 gcgtacctct aaagacattg atttacttat tgccccggat gacatggatg aagcggagca
    14581 ctggatgaag gaagctgggt atgcgtccaa aagcggagaa gtgcgcgtcc ttggcagctg
    14641 gaagtggaag gatcatcatg cctccttctt acatccgcaa aagagggtcg aagtcgagct
    14701 gcactggcgg cttcacccgg atggggggcg ggagccctcc tttgatgagc tttgggactg
    14761 ccggcaaatg ggtaaagccc cagcagttcg agccagtcag atggcaccag cgacttctgc
    14821 cgacagcagg aatgtgacga catcctgcat gtatacgctt ggcagcgagc atcaatttct
    14881 gtacctcagc gcacacggag cgcgtcacgg ctggttcagg ctgcgctggt tggttgacat
    14941 cgacaggctt gcggtacgtg ctgtcgattg gagggcgcta ctgccgcaaa tgcgccgtta
    15001 cggaggcctg cccgcgggcg ggcaggcttg ggcactggcc gctgcgctgt tcggtacgcc
    15061 gatcccggag ccgatgcgtc cgatatcggc tacccggcag gcgcacaggc ttgcgctgag
    15121 cgcgctggct tttatgcagg ccagcgtccc tgcgccgtac ccggttgcca atggggcggg
    15181 tacaggcaga ctcgttcggc cagagctatt gcctaacgta gctttgaccg agtcaatgaa
    15241 taccgcccct tcggatggcg gtatttcagc taacggaacc tcgggcgaag ctgttctgta
    15301 cgccgtcagt agtgatgctg gcatatcgaa agatgccagc agcatccttg gtgacccggt
    15361 gaatacagtg aacactgctg taagtagcct tgccaagcct gtaggtgctg ctacagtcgc
    15421 ctccagtcca gccattgctg gagctacaac aacagcgttt actcctcaac cggttagccg
    15481 cgcttacctg ctttccttaa aggagccaag acacagacta tggtatctca tcagccgttt
    15541 gtttccttct acgagggatt cagtcatttg cccactgcct cgccagctgc attttttgta
    15601 tattccttta cgtccatttc tttggctaaa acgtcgattt tcaaagcact aacccgataa
    15661 ggagtgtaca tgatgactca tctgcgatta tatatgacca agctgtatag cttgaacggc
    15721 ggggcgttat ttcttaatat tggatgtatg atgatcgtca gtctactgga gggtgtcggc
    15781 atttatatgc ttgttcctat gctggcggcc atcggcgtat ttggcggtca ttcagagatg
    15841 ccatttctgt cggatggatt tgattatttt ttgccgtaca ttcctaaaag ctggctgttg
    15901 ccggggatgc taatgttttt cgtcatgctg cttaccgggc aggcttggct tcagcgttac
    15961 cagtccattc ttaactcacg gattcagcag cgttttatgc gttcccttcg aatagacgta
    16021 tacacttcct ttatgaaggc gcagtgggct ttttatttgc gtcagcgtaa atctgatttt
    16081 agccacgtga tgacgaccga gctggcgcgt gtcagtcagg gaacgaattt gcttcttcaa
    16141 ctgaccacgg ccgtcatgtt tacgctaatc cagattgcgc tggctttttg gctatcccct
    16201 tctttaaccg ggctggtgtt tctgagtggc ttggtgttgt ttgtcgtgtt ccgtcgctcc
    16261 atccgaaatg ccaaacaatt aggtgaccgt accactgagc tgtcacagat ttattttgcc
    16321 ggaattacgg atcatatgaa cgggatgaaa gatattaaaa gcaatctgct ggaagcagcg
    16381 aatatccatt ggtttcgctc cctgacgcag cggatggagg ataatacgac tcagtttgtt
    16441 cggcaaaatg cgaccacaca gttttttcat cgcatagcgg cagctgtttt tgtcgttagt
    16501 gtcctatttg tgtcgctcca atggctgcat gttacacctg aaaaactgat cgtgctcatc
    16561 cttatatttt cccgcttatg gcccaggttt gcccttattc aagcgagcct ggaatatatt
    16621 atgtctatga tctctgcttt tgagagtgta actaaagtgc aacgggaatg cgaggctttc
    16681 tcagatcctt ctttaattgg gcttacatcc tctgagaatc atgtcccatt cgattcatcg
    16741 gtaaatcatt tgtcatctac atctgcacgg caacccctat cccttcgtaa tggaatagaa
    16801 tgcagccatt tggattattg ctacgagggt gcagcagtgc ctgcactacg tcatattaat
    16861 ttgttgatac ctgcccgggg aatgaccgcc attgtaggga aatcaggagc aggcaaaagc
    16921 acaatggtcg atgttctaat gggtttttta cgcccaacgg ggggacagat taaaatcgat
    16981 gatcatgtgc tggacgacaa attgctgccg ctgtggcggc agtcgtttgg ctatgtgtca
    17041 caggacccgt ttttgttcca tgcgaccgtc cgtgaaaatt tgaagctggc cgataaggat
    17101 gctagtgaac aacagctatg ggaggcgtta cattttgcag ctgcagacaa ctttgtatcc
    17161 agactgccag aagggctgga cacagtcatt ggtgatcgcg ggattcgtct gtccggggga
    17221 gagcgtcaac ggctggtatt agcgcgggct attttgcatc atcctcctgt actcatcctg
    17281 gatgaagcga caagtgcgct ggatggtgag cacgaggctg caattcaggc agcattggaa
    17341 cggatgaaag gtcaaatgac gttgatcgtg atcgctcacc gtctgtcaac gatcagacat
    17401 gcagatcaaa ttgttgttct ggatcaaggc gaggtcatac agcaggggaa ctaccaccaa
    17461 ctggtagaag aggagcgggg ggcgttcagt cagctacttt cgtatcaaag cactgtcagc
    17521 gccgcccctt agtcataaga gagtcaccct ccataaatat actaaaaatt tttcaacaaa
    17581 aaggcgctaa tattttatat tctgatcctt atgttcctga atataaagta ataagaaaac
    17641 aaagctttag tttgaagagt attgaaatta atgaggtcaa atctttatcc attttggcat
    17701 accaatgtct aatccgtaag cctcacgggg atcttttcgc acaagaaatg aagacgattt
    17761 ataaaaactt gataaatgat tttaaaatac ggaaaatgac aaaaagctaa ataacaaccc
    17821 ccctttttaa caaatggcgt gcatcgatat taatatcgat gcacgccttt attgatggta
    17881 ctgctccata ctaaccgcac agctgtcatc tttgtcatca acatgtcatc attttctttg
    17941 tgacatgttg gcgctgatca atacgttagc gaacattgca tgtcacgtga aatagtgaag
    18001 atttgtaact agcttaaatg atagtgagtg agtgacaatt ggattactga agacgaccca
    18061 atatgcttgt atgcagaaag agtcgcactt caaaaaaatc catgaggtga atgccgaatt
    18121 ttaaattgat ggttaaaggg gatttttagg ggatttagaa aaataataag taagtatttc
    18181 aggaggtttt tatgaaaaag aaaatgatta ttgcacttgg tgcttctgct ataatgctgg
    18241 ctaattttgt aggaagtact tatgcagatt cgaaaacagt agttcctgtt acagctccct
    18301 acaatacaaa tcaaatagca gaatggttag aagcgcatgc aaagccttta aaaacaacga
    18361 atccaactgc acctcttaat gatttaaaac cacttaagaa tatggtaggt tcagcttcaa
    18421 ttgtaggttt aggtgaagct acacatgggg ctcatgaagt ttatacaatg aaacaccgca
    18481 ttgttaatta tttagtatct gaaaagggct ttaccaactt agttttagaa gagggatggg
    18541 acagagcttt ggaacttgat cgatatgttc ttactggtaa gggaaaccca agccaacatc
    18601 tatcacctgc atttaagacg aaagaaatgt tacatctact tagttggatt cggcaatata
    18661 atgctaatcc aaaacataaa tctaaagtgc gtgtcattgg gatggatatt caatcagtaa
    18721 acgaggatgt ttataataat atagtagaat atataaaaag aaacaattca gatcttgtgc
    18781 ctagagtcga aaagaagata agagggctta ttcctgtaac aaaggatatg gatacctttg
    18841 gcagccttac gcaaaaggaa aaagaaaagt atatttcaga tgctaaacaa atcagtgctt
    18901 tattagaaca aaataaaagc tatctaaatg gaaaatccag agagttcgca tggataaaac
    18961 aaaatgcccg tattattgaa caatttacta caatgttagc gtcaccacct gataaaccat
    19021 ccgacctttt tttgaaacat gatattgcaa tgtatgaaaa tgcgaagtgg actgaagaac
    19081 atttaggaaa aaccattgtt tggggacata acggacacgt ttcgaaaaca aatatgattc
    19141 cttttatata ccctaaagta gctgggcagc atttagcgga gtattatggg gaacggtatg
    19201 tatctattgg aacatcagtt tacgaagggc aatataatgt ctacaataat gacggtgaat
    19261 ttggcccata tggaacatta aaatcagatg atcccaacag ctataactac atctttggac
    19321 atgtcaaaaa agatcaattt attatagatt tacgtaagac gaacggagtg acaaaaactt
    19381 ggttaaacca acaacatcca attttcgctg gaataactac ggaaggccct aatataccaa
    19441 aaactgttga tatatcatta ggtaaatcgt ttgatatact tgttcaaatt caaaaagtga
    19501 gtccatctca actacatcaa taaatttgta ataatgtggc tcaacgaagt gtagtattga
    19561 ttgtagtgta gtgttaagtg tcaatagagt tgattaaaaa tgtcagtcat gttattccat
    19621 taaaggggat gtaggataga aacacttcgc catcccccct aaatgaaaat tttctgtctc
    19681 tacatttagt tatttccttt cctgtaaagc tcacgtttct ttacgtttag cagggctcct
    19741 tttctttttg actggagcag gagagatggc gtcgcctgcc acagcttgtt gtgctgtcac
    19801 ggctgctggt ttacgcgcag gacgtttttt cgcagcagga ccaggatcgg taacgacagg
    19861 cttcactgcc tcaatactgg cttggagggc agccattaaa tcaaccacat tggtctgagg
    19921 ctgtgttggg gcaattcgca cctcttcgcc agctacttta tgctggataa gatccagcag
    19981 acgctcgcgg tactgatccg tatactttgc tgcatcaaaa ggggtagata gctgctcgat
    20041 caacattttt gccatggtca gctctttctc tttaacctcc tcctgtccag gtaagttggg
    20101 aacttgagca atgggacgga tttcgtccgg gtaaaacatg gtctccaccg ccaagcattc
    20161 atccagcacg cgaatggctg ccagactact ttttgagcgg atggagattt gggcaattcc
    20221 gattttcccg gtatccttca ttgcattcat gagtagctta tacgcattcg agccagcctg
    20281 atccggggac aaataatacg ttttttgaaa gtagatcgga tcaatttcct gtaaatccac
    20341 aaagtccaaa attacgatat ttttatcggc ttgtccgcta acttgctcca gttcttcctt
    20401 gtcgaacatg acaaatttgc ctttttcata ttcgtaccct tttccaattt cctcccattc
    20461 aacctcctta tcacaaacag ggcatttccg tacgtagctt aatgggctcc cacactcctt
    20521 gtgaatataa cgcatggaaa tgtccttgtc ctcagttgct gagaacattt taactggcac
    20581 atgaaccagc ccgaagctga tcgcgccttt ccagaccgta tgcataccgc cagtcctcct
    20641 ttttttaatc cgcatatttc atatttcgat tccgggcacc cgggctgtga gcatttcatt
    20701 tttcacttag tatgcttcgt acaaaagatt gtatgagatg caaatgaagg ctgcgaattg
    20761 ctttcacttg cgcatggttt cggttttttt ggtgaatgtt aagccatatc cgattcaaag
    20821 gaggtataca actgatgcct agaaaaccct atcctcagca gatcagtcat cgtgtgggac
    20881 aaagtcacat tgcctttcga gggcctgctg gaggcgaaca ggatgcattg ccgcccgagt
    20941 ttgctctttc acatggaacg ccgccgcctt ttcccgtagc tgttgctcat gtggatatgg
    21001 aggctgtagt ttcaacatcg ccttctcata gctttccttc attggatgtg gaacggatta
    21061 tagacgaaga ctaggtgacc tatattttga attttgcaca aaaaaaagag gaggaggaga
    21121 acagcatgaa cgtggaacga gcaaaagcca tttatgattc atccgaaacg attgccgtcc
    21181 aattggatgg caaaccgatt tggattgagc atgtagatga agcgaatggt atggcaacgg
    21241 tacagatcgg cagcagacct ggtgatacac aaaccgttcg tgtagatcga ctggaagaac
    21301 aatagaagag aggctccaac ctaaaaaggc tcgcaattgc tcaatgagca attagcgaac
    21361 cttattttat ataatgaatg cgattgtgaa gacaagttaa acgccagaca agttaatttg
    21421 aaggtggaac tgatttttta cactgcaatg gtcttcaaat gtggagaaac catcaactca
    21481 gcctctgtcg ccatttgaac atcttccacc gacaaacctg gagcaatttc cttgagcatc
    21541 agccctttac ccggaataac atcaatgaca cctttttcgg ttacaatggt ctttaccaca
    21601 tttacagcgg ttaggggcag cttgcattgt ttcagtattt tcggcgcccc atttttgttc
    21661 acatgctcca tggctacaat cactctcttg gctccaacta ccaaatccat ggccccaccc
    21721 atgcctggca cctttttccc tgggatcatc cagtttgcaa ggttgccttt ctcatcgacc
    21781 tccagggcac ccaaaacggt gacgtccaca tgccctccac gtatgatgga aaatgaaagc
    21841 gcactgtcaa taaagcaggc tcctttcacg gttgtaacgt agtttccgcc tgaatcgata
    21901 caatcgagtc tttcttttcc cggagctgct ttggggccaa cgccgacgat tccgttctcc
    21961 gcctgcagca taatattaat attttccggg atgtagtcca ctgccatggt aggtaatcca
    22021 ataccaagat tgaccacttc gccatctttg aattcctggg ctattcttct aataatcaat
    22081 tctctattat tcattgtctc cacccacctt tacaatcgcg tcgacaaata ttccgggaac
    22141 gttgatatga ttggggtcga tttcccccgc tttcacgtat tcgtctgtct gagcaactac
    22201 atactcggct gcggtagcca tcaccaaatt gaagttgcgt gaagagccgt tgatgacaag
    22261 gttccctgct tcatcagctt tatgggctct gataagcgcc acatcggctt tgagcggtag
    22321 ttcgagcaga tattctcttt cgtcaatttt gattttcttt tttccttcct ctacaatggt
    22381 gcctacacct acgggggtta aaataccacc caaaccagct ccgcctgcgc gtattttttc
    22441 agcgagcgtc ccttgcggga agagttgaac atccgcttct tttgtcatca ggagtcttcc
    22501 cgtttccgga ttggagccga tataggatgc aaaaatccgc ttgactctgc cacttttcac
    22561 aagtctataa atagataatt ccgttgtgcc tgtgtcattg gaaataattg taagattatc
    22621 agcggaattg gtgtcgacaa gcgcacgcac cagctcctcc ggaatgcctc cttgcataaa
    22681 acctccaacc atcactgtgt ctccgtcttt aattttctta actgcttctt catcggagtt
    22741 tactttttta ttcatggttc tgtctcctta tctatttttt aggaagcaag ctttattgga
    22801 gataatcgta taggactctt ccatatggaa gtgttaaatc ggcaataaaa tgttttccgc
    22861 caacataagc tctaaccggc aaatctgcca ccggagcgtt gacatggggg atcaggctta
    22921 atctggcagg tcctgaccag gcgcctttta cagtaatatc ttcgagatta tacgccacta
    22981 actgagcaat tttaggggta ccgtccacat caggaattaa tttcagatta acttgcgttt
    23041 ttgcgatggc tttagccgtt tccttttcat caagaacgtt atatttgaaa ggggtggttc
    23101 ccatggctac cagggcgtta ttataatgca aggtacccgt cagcgtctct gtatcctcaa
    23161 cgatcaggcg aggtttcgcc cattttttcg gaaatcccca gatttcacgt ccccccagaa
    23221 tagcaggtgc gttatccaga tacatttggg caacaaaatt acacggttct ccattataag
    23281 tacacggaat gacaatgccg ctttcctcat agcttcctaa accggatgaa tcgggcattt
    23341 tgatccattc ataggaaacc gtattacttc catccggctg aagaggttca gggaccgcct
    23401 gtctaatcgc ggcgggatcg gattcatagg taataataaa gaattcccgg ttgatgaacc
    23461 ggcatggcgg gcgtccataa ctgccgctgg ccgcaggcat ggattggagt gaaagtacat
    23521 ctttttgatt catagcgatc tcccttcctt tttaagaggt atttcaacaa ttatcttgaa
    23581 caagcacttt aaatgagagc attttcaacc agcatggcta ttcccattcc cgttccaatg
    23641 cataacgaga ctacgccata acgtgaagat ctgcgtacca tttcatgaac caacgtaacc
    23701 aataccctag caccgcttgc accaacaggg tgaccaattg cgatcgcgcc gccattgaca
    23761 ttgactttct ctggattaac tccaagctct tttcgcaccg ctagagcttg tgcagcgaac
    23821 gcttcgttaa tttcaaagag atcaatgtca tctatagaca ttccctgttt cttcagcagt
    23881 gacgaaatgg cttttaccgg tcccattccc atatatgcag ggtcaacacc aacaagcgag
    23941 taacctttga tatatgccaa cggctttaac gcatgttcct tacatttgtc ttccgacacg
    24001 actagcatag ccgccgcacc atcattgatg cccgaagcgt ttcccgcagt aaccgttccg
    24061 ttctcttt
//
