LOCUS       NZ_CP025957            20237 bp    DNA     circular CON 13-OCT-2024
DEFINITION  Paenibacillus polymyxa strain HY96-2 chromosome, complete genome.
ACCESSION   NZ_CP025957
VERSION     NZ_CP025957.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Complete genome sequence of Paenibacillus polymyxa HY96-2
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5745779)
  AUTHORS   Luo,Y., Zhang,D., Cheng,Y. and lI,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JAN-2018) East China University of Science and
            Technology, Laboratory of Marine Biochemical Engineering, Meilong
            Road No. 130, Shanghai 200237, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Expected Final Version            :: no
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002893885.1-RS_2024_10_12
            Annotation Date                   :: 10/12/2024 01:33:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,010
            CDSs (total)                      :: 4,854
            Genes (coding)                    :: 4,742
            CDSs (with protein)               :: 4,742
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 76 of 112
            Pseudo Genes (incomplete)         :: 39 of 112
            Pseudo Genes (internal stop)      :: 14 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:53:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1221959
            Orig. end                         :: 1242196
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025957.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="4"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10237)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     misc_feature    284..300
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.33"
                     /tool="antismash"
     misc_feature    complement(385..398)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    complement(1068..1079)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 18.98"
                     /tool="antismash"
     gene            1221..1400
                     /locus_tag="C1A50_RS05270"
                     /old_locus_tag="C1A50_1129"
     CDS             1221..1400
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369715.1"
                     /locus_tag="C1A50_RS05270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1129"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_013369715.1"
                     /transl_table=11
                     /translation="MIRDDILRQQLENARQKLYILQAKHGFNHASVLKQSVIMDNLINQ
                     YNHLFYIKEKKPTA"
     misc_feature    1251..1269
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.6"
                     /tool="antismash"
     gene            complement(1468..2370)
                     /locus_tag="C1A50_RS05275"
                     /old_locus_tag="C1A50_1130"
     CDS             complement(1468..2370)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686326.1"
                     /locus_tag="C1A50_RS05275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1130"
                     /product="DMT family transporter"
                     /protein_id="WP_016821372.1"
                     /transl_table=11
                     /translation="MNKVIAHHSESNRIYYTSTILALLIWSTSFIATKAAYTTFPPLTL
                     GLSRFIIASIVLGIVLLIKKEHVKVKPKDLATISFSGVLGITLYFSMENIGVSLTTASN
                     AALIVASYPAITSLLEFILYKVKLSKYKVCGIALAMIGVYFLTSVGESSDGKNQLIGNL
                     ILIGTGFAWAFYTFMTRKVVDKYPPVTLSFYQTVAGSIFFIPLALLEKDSWQAPTTGSF
                     MLLMYLGVFCSVIAFLLYNYGLIKLSPSSSVSLMNLVPIFGVLFSVLLLHETITWRQII
                     GGLVVIIGVLMSAHQTNRT"
     gene            2531..3391
                     /locus_tag="C1A50_RS05280"
                     /old_locus_tag="C1A50_1131"
     CDS             2531..3391
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="C1A50_RS05280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1131"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_013369717.1"
                     /transl_table=11
                     /translation="MKSKPNILEILRDLNFSEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMVSQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDALEQAAQQGIEVI
                     LVAYGDLNFDFATVYRHDMSEEITSEIGGRWIVLSVDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREELEAKFGPNLIHLRNKFAMGPNGKGYYVPLTEK
                     SIKRV"
     gene            complement(3477..5099)
                     /locus_tag="C1A50_RS05285"
                     /old_locus_tag="C1A50_1132"
     CDS             complement(3477..5099)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429103.1"
                     /locus_tag="C1A50_RS05285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1132"
                     /product="DUF1593 domain-containing protein"
                     /protein_id="WP_103042255.1"
                     /transl_table=11
                     /translation="MRKRKGLSIFVLAMICILIISGCSGKSPAVVKDESVAPTEQPAGN
                     KVENKATKARTVITTDGEVDDMNSVIRFLLYSNEMDLSGIVLTSSVYHYAGDEKAGIKP
                     FRWTGTQWVTDMIDAYGEIYPNLIKHAEGYPKPEYIKSVTKIGNISNKGEMDKETEGSN
                     FLKTLFLDDDQRDLYVQTWGGTNTTARALKSIEDEYKNTDQWETIQKKVSDKLVLYIIL
                     DQDDSYNNYIAKNWPDIRIINDQSNFWHFAYAWKMHTEEVNSKLHGEWNFKNIKDGHGK
                     LLNMYALMGDGNIIKGELDEEQRGSEAYLKKNPQYDKYDFISEGDSPSFFYLIDNGLRS
                     MENPTYGGWGGRFGVVNDKLFRNTVLDYDVHTKKFEAEYSLMRWFDDIQNDFAARADWA
                     IASDYKDANHNPTLTIKEGLDLTASPGENITLHAEGTDPDGDALTYKWWRYFEADTYKD
                     SKVKPAQVKPEMLGDMQLGLHRELAEGEKVNTIDLQGGDTNTASFTVPADAKSGDTIHI
                     IAEVQDNGKHSLKHYQRVIVTVK"
     gene            complement(5336..6418)
                     /locus_tag="C1A50_RS05290"
                     /old_locus_tag="C1A50_1133"
     CDS             complement(5336..6418)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="C1A50_RS05290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1133"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_013369718.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTVIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGIEGLQILKRVGDEFGLATISEIVDPRHLEEAIPYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_feature    7113..7124
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     gene            complement(7148..7408)
                     /locus_tag="C1A50_RS05300"
                     /old_locus_tag="C1A50_1135"
     CDS             complement(7148..7408)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="C1A50_RS05300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1135"
                     /product="hypothetical protein"
                     /protein_id="WP_013369720.1"
                     /transl_table=11
                     /translation="MANRDNQKTELQDHDFEPSLQNAETNWENLIEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEEQLDSDDILD"
     gene            7592..7879
                     /locus_tag="C1A50_RS05305"
                     /old_locus_tag="C1A50_1136"
     CDS             7592..7879
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="C1A50_RS05305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1136"
                     /product="hypothetical protein"
                     /protein_id="WP_013369721.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGYSRTVIRRPDGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEECEPWIGLREQMEQREQEMIINQYEDFTNND"
     gene            8012..9901
                     /locus_tag="C1A50_RS05310"
                     /old_locus_tag="C1A50_1137"
     CDS             8012..9901
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="C1A50_RS05310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1137"
                     /product="sensor histidine kinase"
                     /protein_id="WP_016821366.1"
                     /transl_table=11
                     /translation="MRHVPKAVAALLAVIVILLSLDHIGYAAKMTPEREYKIPSWDMRW
                     GAEDEDGSLDEVNDHSKVWMHIEDDTQLLKQPGNRGTAWIRIKLPSLNDETPAVLFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKNRLGIIGNVM
                     TGDYRDLLGNLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAFFFEQNINSILLIRKFRKLLTAY
                     SLFCFIIMIVNLGAQERLNDVYYFFSVIVLGILLVALMVLLVFASVRMALKGDHEAIIL
                     STGFAFFAVITIVELSWFFIRDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDHTKTLTILDEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALREQGHIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKISFTSAKGVGTEATIRFPVAG"
     gene            complement(10001..10237)
                     /locus_tag="C1A50_RS05315"
                     /old_locus_tag="C1A50_1138"
     CDS             complement(10001..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="C1A50_RS05315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1138"
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_016821365.1"
                     /sec_met_domain="TIGR03793 (E-value: 1e-19, bitscore: 68.2,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMADPKSAIRDVLGVVIPDHIQ
                     IKTVEETSDQFYLVIPPNPSGVLATSQKPRSMW"
     gene            complement(10313..11248)
                     /locus_tag="C1A50_RS05320"
                     /old_locus_tag="C1A50_1139"
     CDS             complement(10313..11248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369724.1"
                     /locus_tag="C1A50_RS05320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1139"
                     /product="hypothetical protein"
                     /protein_id="WP_029514408.1"
                     /transl_table=11
                     /translation="MEWYFAYKEELEKVFRQAEERTATFQAPFQQEGLDYLARFNPLRE
                     DSTRNYICYLLPFWLQELTGLPPETCRKLSLGNVFVMAHYLIQDDVMDTAADNRKTQLA
                     LSQLFYTECQNIYQELFPATSPFWTYARTYVDEWAVSVVSEGAADYFQGDRNKVALKAS
                     PLKMAGTGALLLADHADLIEIVTAMTDLALLVLQMSDDWADWTEDLMEHSYNCLLSHIS
                     AERKKPYCEGLGPQEIQEAIYVRGALASYVNIANQAVQELETMEPTIHGLYRFAHSIAT
                     ELSEEAAEIEGGRSHLRRGGLDYWLSKNMK"
     misc_feature    11320..11332
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     gene            11439..11912
                     /locus_tag="C1A50_RS05325"
                     /old_locus_tag="C1A50_1140"
     CDS             11439..11912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821363.1"
                     /locus_tag="C1A50_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1140"
                     /product="hypothetical protein"
                     /protein_id="WP_016821363.1"
                     /transl_table=11
                     /translation="MKKQWKLTAAILYGGVMMYGTASAGASGIESGNPLQALTPNDSVQ
                     GEAHQWNIDPQDDHGHGHVHRHRHGKGPGGLNHHLNEKVARLLGITPVQLEKELGQGKS
                     LAEVAKSKGIREDQLIDKLKNEMTVDLKRLVNRKGPITFDRKSGTSNEAQLKR"
     gene            complement(12010..12516)
                     /locus_tag="C1A50_RS05330"
                     /old_locus_tag="C1A50_1141"
     CDS             complement(12010..12516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821362.1"
                     /locus_tag="C1A50_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1141"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_016821362.1"
                     /transl_table=11
                     /translation="MKSHVLIYDGYVSFEIMLATYFMKTKGDIVTIGVTKEPVISYEDF
                     KVTPAVALDEVSAEDIQLLIIPGGDNTQLKTNKQLLALIHTLNNDHKVIATICSANELL
                     ELAGVSPKNHVSHPSGLEIHKNIISAKPNKYVDFAIEIGKVMNIYTDDEDFNETIDFFK
                     LFKDS"
     misc_feature    complement(12686..12695)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(12701..13152)
                     /locus_tag="C1A50_RS26035"
                     /pseudo=""
     CDS             complement(12701..13152)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279744.1"
                     /locus_tag="C1A50_RS26035"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKNTGMTRPLDTLGRIVIPKELRNSMGIQAGESLEFYLDVETGLL
                     SMRKYIGVCCHLCYSVQDLSYFRDSFLCKKCIHDLKGNSVI"
     misc_feature    complement(13200..13209)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            13354..14751
                     /locus_tag="C1A50_RS05340"
                     /old_locus_tag="C1A50_1144"
     CDS             13354..14751
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="C1A50_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1144"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_016821361.1"
                     /transl_table=11
                     /translation="MEITPTIQAEVQTYLKRKSLTMTEFGHTIDLNVGTVSGIVTGNRS
                     MSVHQLDSITAGMNLPPDYFYERYIEECIEECPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYLPSLFEVAENVYKDGYSEAAAYLYKKVAESEKQQHSERLAICQYRLFQIK
                     VGQDRAVNLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFAHQMGQLGQ
                     LQYHLVHNSKRKGTEPRKKLSRPLFVYIVYAELLCANACDAKGNHDQALEHIRGYADLN
                     WVKEQDSDTLYWKRKYQQWAKINTYVNRLMSGDISVLPDYVEHIAAEKEILAELLNVLE
                     VANRYNVDVDHILRRFESQIAAYQESPSSDMYTQQVLTEEYVRFWYKIAKYSLNKGRYT
                     YGFKCLLIAFEKAVTINHVLLIANCFGLFLHFKTNAAPKTQAQFHSIYEEVWEKNDQKD
                     GFLLGGN"
     misc_feature    complement(14945..14959)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.68"
                     /tool="antismash"
     gene            14976..15230
                     /locus_tag="C1A50_RS05345"
                     /old_locus_tag="C1A50_1145"
     CDS             14976..15230
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369731.1"
                     /locus_tag="C1A50_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1145"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_016821360.1"
                     /transl_table=11
                     /translation="MNKDEKVTLIQQMEHARQHMHDLYAEYGLGHACVLEQSMLLDELI
                     NQFNRMFQTRKQPHQVLDQILNNDDGMLSSSPHSYYAKL"
     gene            complement(15431..16654)
                     /locus_tag="C1A50_RS05350"
                     /old_locus_tag="C1A50_1146"
     CDS             complement(15431..16654)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821359.1"
                     /locus_tag="C1A50_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1146"
                     /product="acyltransferase"
                     /protein_id="WP_016821359.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSAALLFYNGNKPIGYSRYIGRRFRDIYVPFLCWTVVYWVCTQNW
                     STAQWGNISFYKGMFEEMIIPVSGYHLWFVVMIFQFYIWFPLFAKATEQIRTFLRRYSI
                     KKRKQLVLAVMLIAAAAYALLLQWSYYDMSAWSAWLPSFGQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTDTWRGLAQQTLPWNVFVFIGLFMLMGHTMLIQSGDTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDQRSEPFRRMLNWIGRYSFGGYLAHALVLSFISFYTRPLA
                     LGDHHFTATLITFVVVASASLGISWLFAHLPGGNWIVGSKGRQRLNWRLHFQFLSSKRA
                     SKSTQELG"
     gene            16862..17869
                     /locus_tag="C1A50_RS05355"
                     /old_locus_tag="C1A50_1147"
     CDS             16862..17869
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429118.1"
                     /locus_tag="C1A50_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1147"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_016821358.1"
                     /transl_table=11
                     /translation="MKKTLLVYILLIAAFALYVFRYEQSERLNGAWEEKGLRGSIGETY
                     MMITFQSGLEYWKSGLKGFEDAGDALGVTVEYRGATRYDAQEQMTIIEQAIARKPAGIA
                     ISAIDPHSLIPVINKALDADIPVVLFDAGAPGSRAYTFLGTDNYKAGVTAAEKMAELLG
                     REGQVAVLTLPGQQNHEERSRGFRDTIQRQYPAMKVVEVVDGRADVMVSRDESLRLMKA
                     YPKLAGIFVTEATGGTGVGEAALSQKGSHPLKIISFDTNKATLDMIRDGTISATIAQGT
                     WNMGYWSLQYLFHLHHHLTIPAPSSSGDNTPLPVRVDTGISVVTRANVDDYYAK"
     misc_feature    17874..17888
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            17904..19904
                     /locus_tag="C1A50_RS05360"
                     /old_locus_tag="C1A50_1148"
     CDS             17904..19904
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369734.1"
                     /locus_tag="C1A50_RS05360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1A50_1148"
                     /product="sensor histidine kinase"
                     /protein_id="WP_029514407.1"
                     /transl_table=11
                     /translation="MMPRLRLRNMPLRYQLMVLFLLFGIVPSLGLGLLVNWTVERIIER
                     QVENHTMQLIGKVNEALDTKMENLQNMTYLIAFNPEIGEFWKGRTLADGHAGHTSSVMP
                     ENQGERAKKPLLNQAPGSKQVVSSVQEQDTLYEMKQFLQGFTTLYPEIAGILIVNEKGD
                     YISNEMYARSTRSLTEEDWYAQAAQHAGIFTVLGQPSHRNVTTHVRYKDSEIVSVVRSV
                     TDSETGHVLGVIMIDLKLRAVSQAARDVTLGKSGYVMVTDAKGRSVYMPDMPLIERIPS
                     QWFGPEDSGMFTREAGGRELLFMFQASEFTGWRTVGVFPARESTLEVRQIQFYVVCFVF
                     IVCLFGLTASLRLSSSIAQPIFRLMSYMRTAETGDLTVRQWSERGDEIGMLGRSFNRML
                     EQIRRLMSLSELRERQKRDAELRSLQEHIKPHFLYNTLDTIHWMARKNGADDVSDMVGA
                     LSRLFRLGLSKGDDFIPLRSEIEHISSYMQIQQTRYRDRLRWELNVPDGLKDLFVLKLM
                     LQPVVENAIYHGIKARRGPGTICVEAKAEDGKLLLTVRDDGAGMTAERLCELREWLEIP
                     LEAMEGRRKQKEVRTNGRSYGMLNVQARIRLSFGEEYGITLDSKEGTGTCVTITHPLLL
                     DMAQLKKPYDKGEGQDDEIQGNRQRDNGESD"
ORIGIN
        1 tgaatacgga attgggggtt aacgatcaac tggaattatg gtcaggaatt gcctttggag
       61 ttactttttt agcgagcgcg ctgattgccc cgttttgggg ctcgctggca gataagtatg
      121 gacgtaagcc gatgctgatt cgttcagggt ttagcctggc tgtattgtat ctggtatgtg
      181 ctttagtgac agacccatat gtatttgtag gagttcgctt gtttcaagga cttctctccg
      241 gatttattcc tgcggcgatt gcgctggtcg gaacgggctc gcctgaagaa aaaacgggct
      301 atgcccttgg cattatggcg actgctggag cgactggcag cattataggt ccgctgatcg
      361 gtggtgtggt gagccattat tatggcaatc gaaatgcctt ttttttctca gcggctcttg
      421 ttctggtatc tgcgttcatc gcgacatttg gcgctagaga ggatagcttc aagggcacca
      481 gtacccgctc gcatgttcgg gatgatatca aagaggctat tgctaatcgg ccattatact
      541 ttttgcttat tctagctgga ttaagtacct tttctgttat gatcttggaa ccgttaatta
      601 cggtgtatgt gcttgaaatg ggtgtggacc gtagccatgc gtctttaagt tccgggattg
      661 tattctcagc tgtaggcatc gcggcagtgc tgatggctcc ccgatggggc cggattggag
      721 ggaaaatcgg ctttgcccaa gtgttgctga ttgggctgat cggttcgggg attgggaaca
      781 tcttgcagtt ttttgtaacc aactttgttg gttttggtgc gcttcggttt ggatatggat
      841 tgttttatgc gtctgtcatg ccggcgatta atgccatgac tgtggaagtc accaagccgg
      901 agtttcgtgg acgagccttt agcctgaatc aatcagctac ccaactcgcg acgatggcgg
      961 ggccgctgat tggcggcatg cttggtagct ggatgcccat tcgctggatc ttcgtattaa
     1021 acggtggcat cttgctggtt gcagcgttgt tgctatgggc gaagggaaaa aacgttttcc
     1081 cgatttcagc ccaaaataaa gcaacggatc agaatattca ttctgccgga taggccaatt
     1141 agataattat cccaaaccct tatttttagt atattattca taacccttta cactgatcat
     1201 atgacaggga gggatatatt atgataagag acgacatttt gcgtcaacag cttgagaatg
     1261 cccgtcaaaa gctgtatatt ttacaagcaa aacatggctt taatcatgcc agtgtgctca
     1321 aacagtctgt aattatggat aacctcatca atcaatataa ccaccttttt tatataaaag
     1381 aaaaaaagcc gactgcatag atataaccaa ctgggcgaga tcttttaaaa aggccactcg
     1441 cccttgtatt gtagggctgc aatatcttta ggtacggtta gtttgatgcg cactcatcaa
     1501 gacccctata ataacgacca agccgccaat gatttggcgc catgtaatcg tttcgtgcaa
     1561 tagtaagaca gagaacaaca ccccaaatat cggaaccaaa ttcattaaag aaacggaact
     1621 gctcggtgac agcttgatta atccgtaatt ataaagcaaa aatgcgataa cggagcagaa
     1681 cacacccaga tacatgagca acataaacga tcccgttgtc ggagcctgcc agctatcctt
     1741 ttctaatagg gctaacggta tgaaaaagat actacctgca acggtttgat aaaaagataa
     1801 cgtcaccggc ggatatttgt ccacaacctt acgcgtcatg aaagtgtaga acgcccacgc
     1861 aaatccggtg ccaatcaata ttaaatttcc gatgagttga ttcttaccat ccgagctttc
     1921 gccaacggag gttaagaaat ataccccgat catggccagt gctatgccgc agactttata
     1981 tttggataat ttgactttat acaaaataaa ttcaagcagc gatgtaattg caggatacga
     2041 tgcgacaatt aatgctgcgt tggaagcggt cgtcaggcta acccctatat tctccattga
     2101 aaaataaaga gtgattccca aaaccccact aaacgaaatc gtagccaaat cctttggctt
     2161 tactttgaca tgttcttttt tgatcagcag aacgatacct agtacgatgg aagctatgat
     2221 aaatctggat agacccaagg taagaggagg gaacgtcgta taggctgctt tggtggcaat
     2281 aaacgatgtg ctccagatca atagggctag aatcgtagaa gtatagtaaa tccggttgct
     2341 ttcgctgtga tgagctatga ctttgttcaa gttatatcct ccctgagttc atcccctatg
     2401 aaatatgata gtgatagtag ctactatagt tactactatg aaaatgctac taaaaagata
     2461 atttgtatat cagtttttgt caaggggaag tgatatagta aggaagaaca tgaattgagg
     2521 agaagacgtc atgaaatcaa aaccaaacat attagaaatt ctacgtgatt tgaattttag
     2581 tgaatatgaa gccaaggctt atgtgacctt attggaaagc tcaccacttt cgggatatgc
     2641 cgtttcattg aactctggag taccgagatc caagatttac gaggttttgt cgggaatggt
     2701 caaccgtggg gacatcatgg taagtcaaga aaatacacct ctatatgtgc cgcttcctcc
     2761 acatgaattg attgcccaga gaaagcgcaa agcagagcag attttcaacg tggcgcaaga
     2821 gagtttggag cagtacacag catcgtttca aaacagagag aacatttgga atatttcggg
     2881 gtatgaagcc attatcaatc gcattaatga aggcgtgaag ggagcaaaac accgaatttt
     2941 actggaaatt tggaaagagg atgccgaggt gttccgggat gccttagagc aagctgctca
     3001 gcaaggaatt gaggtgatcc ttgtagcata tggtgatctt aactttgatt ttgctactgt
     3061 ttaccgccat gatatgagtg aggagattac gtccgaaatc ggtggtcgat ggattgtgct
     3121 tagcgtggat gaccgggagg ttgtagctgg catactttca cttggtgatg acagccgtgc
     3181 tgcatggacg ctacacccgg gtcttgtaat gccgattacg gaagtgatta ttcatgatat
     3241 ttatatcatg gaaatcctat atgagttccg tgaagaattg gaggccaaat tcggccctaa
     3301 tctaatccat cttcgcaata aattcgccat gggtccgaat ggaaagggat attatgttcc
     3361 tttgactgaa aaaagtatta aacgtgtata gagattgtcc gaggtccgat acgcaaaaat
     3421 aaacaggccc atggagtatg attccatgag cctaatttat tgagtgctgt cttctgttat
     3481 tttacggtta caatcacacg ctgataatgt ttcaaagaat gtttaccatt gtcctgtact
     3541 tctgcaatga tatgaatcgt atccccagac ttcgcatctg ccggaactgt aaaacttgca
     3601 gtatttgtgt cgccaccttg caggtcaatc gtgtttactt tctcgccttc agctaattct
     3661 cggtgaagcc caagctgcat atcacccagc atttcaggtt taacttgcgc gggtttgacc
     3721 ttagaatctt tataggtgtc agcttcgaaa tatctccacc atttataggt caatgcatca
     3781 ccgtcaggat ctgttccttc tgcatgtaga gttatgttct cccctggact agccgttaga
     3841 tctaatcctt ctttaatggt caatgttgga ttatggttgg catctttata gtcggaagca
     3901 atagcccaat ctgcacgggc agcaaagtca ttttgaatat catcaaacca acgcatcaga
     3961 gagtactctg cttcgaattt tttcgtatgc acatcataat ctaacaccgt atttctaaat
     4021 aatttatcgt taacgacacc aaaacgacca ccccagccac cataggttgg gttttccatg
     4081 ctccgtaatc cgttatcaat taaatagaag aaggatggag aatctccttc ggaaataaag
     4141 tcatacttgt cgtattgtgg atttttcttc aagtaggctt cactgcctct ttgttcttca
     4201 tccaattcac ctttgatgat attgccgtcg cccatcaagg catacatatt tagcagcttg
     4261 ccatgaccgt ctttaatgtt tttgaagttc cattccccgt gtaacttgct gtttacttct
     4321 tccgtgtgca ttttccaagc ataagcgaaa tgccagaagt tagattggtc attgataatt
     4381 ctgatgtcag gccaattttt ggcgatgtaa ttattgtagc tatcgtcctg gtccaaaatg
     4441 atgtacagaa cgagtttatc acttactttt ttctgaatcg tttcccattg atctgtattt
     4501 ttatattcat cttcaatgga tttcagagct ctggctgtgg tattggttcc accccaagtt
     4561 tgtacataca gatctctttg gtcatcgtct aggaaaagtg ttttcaggaa attcgagcct
     4621 tccgtttcct tgtccatttc acctttgttt gaaatatttc cgatcttggt aacgctttta
     4681 atatattcag gttttggata cccttcagca tgtttgatta ggttggggta aatctctcca
     4741 taggcatcaa tcatatccgt tacccattgg gttccggtcc atctgaatgg cttgatgccg
     4801 gccttttcat cacctgcata atgatatacg gagctagtca gtacaatccc ggacaaatcc
     4861 atttcgttag agtagagaag aaagcgtatg actgagttca tatcatctac ttctccgtca
     4921 gtagtaataa ccgttctagc cttggtcgct ttattttcca ctttatttcc cgctggttgt
     4981 tctgttggag caacgctttc atcctttacg acggctggcg acttaccact gcaaccactg
     5041 atgattaaaa tacatatcat agctaacaca aaaatgctta acccttttct ttttctcatt
     5101 tctgttcccc tctctgaacg tttctatgat gattttttag gattataacc atgtaggtat
     5161 tgttattatt caagatttag gcataaaaaa aacctaaaca tatatatgtc tcaacaaaag
     5221 tcgagcatat atacatttag gttttgcctg catgatcagt cacaatcctg attagattct
     5281 acatcataat ctgacaaaat gaaagcggtt tatgattctt agcacaaaat tagttttacg
     5341 ctttgaataa accggattct ttaacttcag acaggaagtt gtggaattca gggatgttca
     5401 gctgttgctg agcatcggac aaagcgactg ccgggttcgg gtgaacttct accatgatgc
     5461 cgtcggcacc agcagccagg gcagctttgg cacaaggggc caggatgtct ttacgtcctg
     5521 tagagtgagt tacgtccacc aatacaggca gatggctttc ctttttcaaa atcggaacag
     5581 cggaaatatc cagcgtgtta cgtgtccatt tttcatacgt acgaataccg cgttcaatca
     5641 gcatgacttg tgtattacca cgggatacga tgtactcagc agcatgaagg aactcttcca
     5701 tggtggcagc caatccgcgt ttgagcagaa ccggagttct cgtttcaccc gcagctttca
     5761 gcaattcaaa gttgtgcatg ttgcgcgcgc caatttgaat gatatcgatg taagggatcg
     5821 cttcctccaa atgtcttgga tcgacgatct cactgattgt agccagcccg aactcgtcgc
     5881 caacgcgttt gagaatttgc aggccttcaa tacccagtcc ttggaaatca tacggagatg
     5941 tacgtggttt gaacgcacca ccacgcagaa tcggcacacc ggcttccttg agagctgctc
     6001 ctacctcgcg cgtttgttga tagctttcca ccgagcaagg tcctgcaacc atgatggagg
     6061 ctttgccacc taccagtgtg tctttaacct tgataaccgt gctatccggc tgatttttgc
     6121 ggctgacaat caaatgtttt ttgtgttctt ctttttgata gttcagagaa gccttgaaaa
     6181 tatttttgaa caactggcga attgtagcat cgtcgaaagg tccacgatta gctgcaatca
     6241 gcttgtccag catttgttgc tcacgcactg gatcaaagtc aggcactcct tgagcttctt
     6301 tcaattttcc aagctgtccc gccagttcag cgcgttggga cagcagctcc agcaattgca
     6361 agtttgtagc atcgagctgt tcccgcaaca gctccaaaga attttcattg gttgacatac
     6421 agtacaccct tcccgaattt aaattgtttt ttctttcagc ccttggactt tttgcagaaa
     6481 ataacacaaa aaggcactcg tcgcaaggga cgaatgccgt ggtaccaccc taattacaga
     6541 agtatacatg caagtcgtca acgtcattca atcgacggca gtaacctctg agcttgatgc
     6601 ccgtaacggg ggcttccgga aacctctact gcggtcaaag gaatgaatcc ttctgtcgtc
     6661 ggttcaaggc tcgactcggg agtgaatttc aacgcgggat agcggtacgc tctcagcaat
     6721 acgtaccttt ctgtgggaat ccgatgacgc ttacttgtct ccgtctatgt ctttgttcat
     6781 ggtattcaaa agatttgacc ttattttaaa caaagtggat gcagaaggca agccctgatt
     6841 tccgattcta gtttttgcat tccctatctg ttctttcatc ttgcttgatc cctgggttcg
     6901 ggcttcgctg atgcgactcc tcgtgggtta tcttcggcta aggtatcatc cgtatgagtc
     6961 ttgtccgcag tcctgcggtc atcctcttct acaggattca aggctttata gcgtttgtac
     7021 tccatatcag cctgagacat cggatcttta tacataggag attggtcaac tcctttcggt
     7081 gtatatactt cattacccgc atagcaggat gagaaatcgc tttcttatat cctatcatat
     7141 gcagtaatta atccagaata tcgtcactgt ccagttgctc ttcttcatcc ccgtctgtac
     7201 cgttcagcaa atctgtacca tgcaggaatt cagcaggcgc agagggatca acaggactat
     7261 tcggtgttag ttcatcggca tcaggcacgt cctccagagg agtatccggc ccctcaatca
     7321 gattctccca gtttgtttct gcattttgca gggaaggctc aaaatcatga tcctgtagct
     7381 cagtcttttg attgtcgcga tttgccatct aactcagctc ctttactttt tgttgcttat
     7441 ttcgacctta cccaaactgc agaatggcta aacttagagt tagtgtgtct gtaaaaagtt
     7501 aaaatcatgc gaatagagat atgctctttc ccaattagcg tttttttggt aactgctgtg
     7561 atatgataaa gaggagttgg agggatatga attggaatgg tacatgtttg gtccgatgat
     7621 tagccgaatc cgagtcggtc aaaaggcgtc tactccaggt tattcgcgta ccgttattcg
     7681 gcgtccagat ggtttatatt ggacagacgg cggacaggcc ggaaaaatag tagaaatacg
     7741 cgattattta ttctccgata tttggacgat ctatgaggat gaagaatgtg aaccttggat
     7801 agggcttaga gagcagatgg agcaacgcga acaggaaatg atcattaatc aatatgaaga
     7861 ttttacaaat aatgattaaa aagaacatga tacccttatt atgaagaagg tatgaacatc
     7921 atcgtataga ataatataat ttcaggaaga taaaaatgtt aaaacatata caaatttgta
     7981 aatcctacta cgtaactttg aggtgcttaa tatgaggcat gtgcccaaag ctgtcgccgc
     8041 tctgctagcg gtcattgtga tactattgtc gctggaccac attggctatg cagccaaaat
     8101 gaccccggaa agggagtata agatcccctc ctgggatatg agatggggag cagaagacga
     8161 ggatggctct ttagatgagg taaatgatca cagtaaggtc tggatgcata ttgaagatga
     8221 tacacagcta ctcaagcagc caggcaatag aggcaccgcc tggattcgta ttaagctacc
     8281 ttcgttaaat gatgaaacac cagcggtgct ttttgaaaat atttatggca ggcacattac
     8341 gctgtataag gatggcacca atttttatga atcgtaccgt ggctataatt atgagaataa
     8401 tcgtattctg attccgctga agccagaaga cagtggtaaa acattataca tatggacgga
     8461 aagcagcaaa aatagactgg gcattatcgg aaatgtgatg actggtgatt atcgtgactt
     8521 gttaggaaac ttggtcagaa tggatgtctt ggatattgta ctaggcagta catttatctt
     8581 tatcgccctg gtgctattga tttgctcgtt tttcctgttc cgtccaagta tggcgatgtg
     8641 gttgtcccta agtgcgattg tattgtctat cggtttgatg attgtaacgt attcaccgtt
     8701 tttatatacg ttctatcgcg gctatggcaa gctgtattta caactttttg atgtggcgct
     8761 atttattctg ctgccttcat tagccttctt ttttgagcaa aatatcaatt ctattttact
     8821 gattcggaaa ttcagaaaat tgttaaccgc ctactctttg ttctgcttca tcatcatgat
     8881 tgtgaattta ggagcacagg agcgactcaa cgatgtatat tatttcttta gtgtaatcgt
     8941 cctcggtata ttgctcgtag ctttgatggt acttttggta tttgcttcgg ttcgcatggc
     9001 gcttaaggga gaccacgaag cgatcatttt atcgacaggc tttgcatttt ttgcagtcat
     9061 cactatcgta gaactcagct ggttctttat ccgggacgga cactacaata tgtttttatg
     9121 gaaatggggc gtgttcggtt ttgtcctggc attgattgcg atcttgggca gaaggctggc
     9181 ggaaaagcac aagcaggtgg ttcggtattc cagagaactg gagatgttca ataatgagct
     9241 tcaacgttca gagaaaatgg agattattag cgatttggct gcatctgtag ctcatgaagt
     9301 gcgcaatccg cttcaggtta cacgtggatt tcttcagttg atgagcaagc aggaggatgg
     9361 taaaaacaaa gactatctgc atatcgctct ggaggagctg gatcgagcgt ccgcgattat
     9421 taccgatttt ctgacttttg ccaagccaga gtttgaccat accaaaacgt tgaccatatt
     9481 ggatgagttc aagcatattg aaggaattat cagtccaatg gcaaatttgc aaggtggcaa
     9541 aatttcgctg gatattcccc aggaaattaa agtgcgtggg aattcctcca aattcaagca
     9601 ggcatttatc aatattatca aaaatagtat tgaagcgctg cgagaacagg gacatattca
     9661 tatatgggct tatgtggaca atggagaagc agtcattcat attcgggata atggtgaagg
     9721 gatggatgct cagaccttat ccagactagg tgagccttat ttttcgaata agactaaagg
     9781 cacgggtttg gggatgatgg tgacatttcg gattattgaa acgatgaatg gtaaaatatc
     9841 ttttacaagt gcaaaagggg tgggaacaga agcgaccatc cgcttccccg tagccggata
     9901 acatccggct tttttgcttt cggagaaaac ggagggaagc ttgctgagcc cacccgcctg
     9961 agattaagaa gtatagatta aataagctac aagtgccaat ctaccacatc gagcgaggct
    10021 tctgggatgt agcaagcaca cctgaagggt ttggagggat tactagatag aactggtcag
    10081 acgtttcctc taccgttttg atttggatat gatcggggat cacgactcct aacacatcac
    10141 gaattgcaga tttgggatct gccatcagtt tttctctgaa actggcatcc tcccaagctt
    10201 tttgaatgac ttgtgtttga agaacttcag tagccatcaa aaatcaccct ctcattcgat
    10261 tggttatatt tacctagtca gtataccacg taagactcag aaaaatctag cattacttca
    10321 tatttttgga gagccaataa tcaagcccgc ctcttcgcaa atgtgagcgt ccgccttcaa
    10381 tttctgctgc ctcttcgctg agttcggttg cgatggaatg tgcgaaccta tacaggccgt
    10441 ggatagtagg ctccatcgtc tctagctcct gaacggcttg attcgcaatg ttcacatagc
    10501 tagcgagtgc gcctcgcaca taaatcgctt cctgaatttc ttgtggtcct agtccttcac
    10561 agtacggctt cttccgttcg gcgctaatat gggacaatag gcagttatag ctatgctcca
    10621 tcaaatcctc tgtccaatct gcccaatcat ccgacatttg gagcacgagc agggccaaat
    10681 ccgtcatcgc tgtaacgatc tcgatcaggt cagcatggtc tgcgagcagt agagcacccg
    10741 ttccggccat ttttaatgga ctggctttca gtgcgacctt atttctgtca ccttgaaaat
    10801 agtctgctgc tccttcggac accacactaa cggcccattc gtccacatac gtccgggcat
    10861 atgtccaaaa aggggaggtt gccggaaaaa gctcctgata aatgttttgg cactcggtat
    10921 agaaaagctg gcttaaggca agttgcgttt tacggttgtc tgctgctgtg tccatcacgt
    10981 cgtcttggat taaataatga gccatgacga acacgttgcc gagtgacagc ttgcgacatg
    11041 tttcgggagg cagtccggtg agttcctgca gccaaaatgg aagcaaatag catatgtaat
    11101 tacgcgtact gtcttcacgc aacggattaa accgtgccag gtagtctaac ccctcttgct
    11161 gaaagggagc ctgaaatgtg gccgtccgtt cctccgcttg acgaaatacc ttttccaatt
    11221 cttctttgta tgcaaaatac cactccatgg ccatcacccg catctcttat aaatgttttt
    11281 gtagcgactt ctagttgtta cccgccattg tacaacagat tgcaattttc aagaatttgt
    11341 tatttttaaa taaggaatgt tgtgaaaaac atataaaatg aataaaaaag ctgaaagaga
    11401 aaatatagat gaaaaaggat gaaaggaggg gccacaacat gaaaaaacaa tggaaattga
    11461 ccgctgctat cctatatgga ggagtgatga tgtatggtac tgcgagtgca ggagcatccg
    11521 gtattgaatc gggtaatccg ttgcaagctc tcactcccaa cgattctgtc caaggagaag
    11581 cccaccagtg gaatattgat ccacaggatg accacgggca tggacatgtg catagacata
    11641 gacacggcaa agggccgggc ggcttgaatc accatctcaa cgagaaagta gctaggctgc
    11701 tgggtatcac ccctgtccag ttagagaaag agctggggca agggaaatcg ttggccgagg
    11761 tagctaaaag caaaggcatt cgcgaggatc aacttattga taaattgaag aatgaaatga
    11821 ctgtggattt gaagcggctt gtaaatcgta aaggtccgat taccttcgat cgtaagtccg
    11881 ggacttcgaa tgaggctcaa ttgaagcgtt agtctgaagt agaatcgttt tacgacaaaa
    11941 aaggatgggg agaacccatc ctatccttat atttcaactt ccttcataaa gtgactgttg
    12001 tgaggagaat cagctatctt taaaaagctt aaaaaaatca atggtttcat taaaatcttc
    12061 atcatccgta taaatgttca tgaccttacc tatttcgatt gcaaaatcta catacttatt
    12121 cggtttagca gatatgatat tcttgtggat ctccagaccc gatggatgac tcacatgatt
    12181 tttaggagaa acacctgcta gctccaatag ttcattggca gaacaaatgg ttgcaatcac
    12241 tttatgatca ttattcaggg tatgaatgag agctagaagt tgcttattcg tctttaattg
    12301 agtgttatct ccaccaggta taatgaggag ttgaatgtcc tccgcagaca cttcatcaag
    12361 ggctaccgca ggcgtaactt taaaatcctc ataggaaata acaggttctt tggttactcc
    12421 aatcgtaaca atatcccctt tggttttcat aaaataggtt gccagcataa tttcaaaact
    12481 aacataacca tcataaatta gaacatgtga cttcatttat acacccacta acaatttttt
    12541 agtttaagtc cgttaaaagc gtctttagga agattacata tagtcagaat atatcatctt
    12601 gaagagttta aatccatatt ttacagaaat atcaataagt tttggtaatc taacttgttg
    12661 aattttggtc agtatggatt caaattaaaa aaataaccag tcaccttgaa attaacagcg
    12721 actggttatt gagttttgct cggatgcgag tgaagtgaaa cctacaatag cttttaagct
    12781 gggaaatacg gctatgtgac acgccaatcc attcagcata ttcgccttgc ttggctgtgg
    12841 gatgctcacg aatgaggctt cttagatgtt caaccaaagt tgtgatgacg atcaaatgac
    12901 gctgtttcct ttcaaatcgt gtatgcattt tttacataaa aatgaatctc tgaaatagct
    12961 taaatcctga accgaatagc ataaatggca gcaaacgccg atatatttcc gcatacttaa
    13021 caatcctgtt tcaacatcca agtaaaattc caaagactcg ccagcttgaa ttcccataga
    13081 gtttcgcaat tccttaggaa taacaatccg gcctaacgtg tccaagggac gtgtcatacc
    13141 tgtatttttc aagtgacctt ctccttatca taataatcta tcaaccaata atctcctaat
    13201 aaaaaaataa aaatctataa aataaaagta tttatcgatg ttccaaaaga tggtattatc
    13261 atgaatgaaa aacaataagt atactattag tttcaaaact atatgaatta ttgaaatggg
    13321 aatctatgaa gatgctgaaa gggtggttta tccatggaaa tcacacctac gatacaggca
    13381 gaagttcaaa cctatctaaa acgcaaaagc ttaaccatga ccgagtttgg tcacacgatc
    13441 gatttgaatg taggtacagt tagtggtatt gtgacgggca atcgatctat gtcggttcac
    13501 caactggata gtattactgc gggaatgaat ttaccaccgg attattttta cgaacgctat
    13561 attgaagaat gcattgaaga atgtccgctc aactggaaaa aaatcagccc gttcctgtac
    13621 cgatgcattg agctagggcg attggactgc ttgcagcgag ttgtcattct attattggat
    13681 aaccctaatt atctgccatc gctctttgaa gtcgccgaaa atgtgtacaa agacggttac
    13741 agcgaagcag ccgcatacct gtacaaaaag gtagctgaga gcgagaagca acagcattca
    13801 gaacgattgg caatctgcca gtatcgcttg ttccaaatca aagtcggaca ggatcgggca
    13861 gtaaaccttc aggctgctat tgaattcgcc ccttttgtgg atcgcttaga tgagatagag
    13921 caactggatg ctttaaaaga tttggcgaat gtctatagat cattaagcat gtgggataag
    13981 gtgtatgaat tcgcacatca aatgggtcag ttaggacaac tccaatatca tctggttcac
    14041 aattccaagc gaaaaggaac agagccacga aaaaagctaa gcagaccatt gtttgtatac
    14101 atagtttatg ccgaattgtt gtgtgctaac gcttgtgatg ccaaaggcaa ccatgaccaa
    14161 gcattagagc atattcgtgg ttatgctgat ttaaattggg taaaagagca ggactctgat
    14221 acgctttatt ggaaacgcaa gtatcaacag tgggcgaaaa ttaatactta tgttaacagg
    14281 cttatgtctg gtgatattag tgttctgcca gattacgtag aacatatagc tgccgaaaaa
    14341 gagattttag ccgagctatt gaatgtcctt gaagtggcta atcgctataa tgtagatgta
    14401 gatcatattc tccgacggtt tgaatcgcaa attgcagcgt atcaggagtc accttcttct
    14461 gacatgtaca cacaacaagt gttaacagaa gaatacgtaa ggttttggta caagatagcc
    14521 aagtacagcc taaataaagg cagatataca tatggtttca aatgtttatt aatcgccttt
    14581 gaaaaagctg ttacaattaa ccatgtatta ctcattgcca attgttttgg attatttctt
    14641 catttcaaaa caaatgcggc acctaaaaca caagctcagt tccattctat ttatgaggag
    14701 gtgtgggaga aaaatgatca aaaagatggc tttttgcttg gcggtaacta gtttcttact
    14761 ggtattcaca gtaccagctc aaactgcaaa tttaagccat ggcacgatcc aagttcaagg
    14821 acacattggt ggatcttgac gagtactaat tcattttatt ggccagctta ttgctggtct
    14881 ctttttgtat tattttgtaa ttttttgctt caaaattgat cttggcctat ttgtacatcc
    14941 cttcttaaaa tgaaattcat gaggaggtat gtaggatgaa caaggatgaa aaggtaacgt
    15001 taattcaaca aatggaacat gccagacaac acatgcatga tctttacgca gagtatggcc
    15061 taggacatgc ctgtgtactg gagcagtcta tgcttttgga tgaactgatt aatcagttca
    15121 accgtatgtt tcagaccagg aagcagcctc accaagtttt ggaccagatc cttaacaacg
    15181 acgatggtat gctgagttca tccccccatt cctattatgc aaaactgtga tttctcccac
    15241 gtaatgctta taattattca atataatgac ttattttaaa ataaaataca tatccatgtc
    15301 ataaaatgtt aatcagtttg gaacatgatt catcatactt agacagcaaa aaagcagagc
    15361 tcaatacgtg agccctgcaa aagcctttga cggtatttga atccctatgc tgaaacgctg
    15421 gggcagaaga ttagccaagc tcctgcgtgc ttttggaagc acgtttggag gaaaggaact
    15481 gaaaatgaag ccgccagttc aatcgctgtc tgcctttgga gccaacaatc cagttgccgc
    15541 caggcagatg ggcaaagagc cagctgatac cgagagaagc acttgccacg acgacaaacg
    15601 taatgagcgt agctgtaaaa tgatgatccc ctagggcaag cggacgggtg taaaaggata
    15661 tgaaggacag cacgagcgca tgggccagat atcctccgaa ggaatagcgt ccgatccagt
    15721 ttagcatacg acgaaacggc tcggaacgct ggtctttttg cagatgaagt agcagcccat
    15781 acaacaaaag caactgcgag acaatcagta cgaaggtgct tggcttcaga taggtagaaa
    15841 tattgagatt gatcgtatcg cccgactgga tcagcatcgt atgacccatg agcatgaaca
    15901 gaccaataaa aacaaataca ttccatggca acgtctgctg ggccaatccc cgccaggtgt
    15961 ccgtcatata ggcgcacact gcgcccagca taaaatagaa aaaatacata acaaagttat
    16021 aagtgcggta atctaacaaa gtctgcccaa aggacggcaa ccaagcgctc catgcagaca
    16081 tgtcatagta ggaccattgt aacagcaacg cataagccgc agcagcaatc agcataacag
    16141 ccaaaacaag ctgcttgcgc tttttgatgc tataacgacg tagaaacgtt cgaatctgct
    16201 cggttgcttt tgcaaataaa ggaaaccaaa tataaaactg aaagatcatg accacaaacc
    16261 atagatgata tccgctgacg ggaataatca tttcctcgaa catgcctttg taaaaggata
    16321 tatttcccca ctgtgcggtt gaccagttct gagtacacac ccaatagaca accgtccagc
    16381 agagaaaagg aacataaata tctcgaaacc gtctgccaat ataacgggaa tagccaatcg
    16441 gtttgttacc attataaaat agcaacgccg cagacaggaa aacgaacgtc ggtgtgccaa
    16501 aacgtgtcaa atggtacagc atcgcgagca taacggaatc cggttgttgg atgtcgctgc
    16561 gataaatata ttcgccaatg caatgctgaa gcacgacagc gaggtaggca agaccccgta
    16621 gttctgtcca ctccgcgata cgcggcttgc tcatccatat cactcctttt cctcaagatt
    16681 cgcacatgtt tttcctagca caattgtagg tattgtatcg taggaacatt agtgcaggat
    16741 taacgctacc tgaaagtatg gagagtgaag tggttccaat ttaatatgat tgcgtttaca
    16801 atctaaataa aaacaaagta aactcaaatt taaggatacg cataggaaga ggagaggaag
    16861 gatgaagaaa acgctgctgg tgtacatttt gttaattgcg gcctttgctc tctatgtgtt
    16921 cagatatgaa caatccgagc ggttgaatgg agcttgggag gaaaaagggc tgcgaggcag
    16981 catcggagaa acgtatatga tgattacgtt ccagtccggt ttggagtatt ggaaaagcgg
    17041 gctcaaaggc ttcgaggatg ctggggatgc cttgggggta acggtggagt accggggggc
    17101 gacccggtat gatgcacagg agcagatgac catcattgag caggcgattg cccgtaaacc
    17161 cgcaggcatt gccatatcag cgattgatcc acactccctg atcccggtca ttaataaggc
    17221 gctggatgcg gacattcctg tcgtgctgtt tgacgctgga gcgccgggga gccgggcgta
    17281 tacatttttg ggcacggata attataaggc gggtgtgacc gctgcggaaa aaatggctga
    17341 gctgttggga cgtgaaggcc aagtcgctgt tctgacactg ccggggcagc aaaatcatga
    17401 ggaacgctcg cgcggctttc gcgataccat tcagcggcag tatcctgcca tgaaggtggt
    17461 ggaagtggta gatggtcgtg ctgacgtgat ggtgtccagg gatgaatcgc taaggttgat
    17521 gaaagcttat ccgaaactgg cgggtatttt tgtgaccgaa gccaccggag gaacaggtgt
    17581 gggtgaggcg gcactgagcc aaaaaggcag tcatccgcta aaaattattt cttttgatac
    17641 gaataaagcg acactggata tgattcgtga tgggaccatc tcggcaacga ttgcgcaagg
    17701 gacatggaat atgggctatt ggtcactcca atatctgttc catctgcatc atcatttgac
    17761 aattcctgca ccttcttcgt ctggagataa caccccgctg cccgtgcggg tggatactgg
    17821 gatttccgtc gtcacccgag cgaatgtaga tgattattat gcaaaataaa tattggaagc
    17881 gcatccactt agggatgcat caaatgatgc cgaggttacg cttgcgcaat atgcctttac
    17941 gctatcagct catggtgctg ttcttgctgt ttggcatcgt gccttcactg ggactaggcc
    18001 tgctggtgaa ttggacggtg gaacggatta ttgagcggca ggtggaaaac catacgatgc
    18061 agttaattgg caaggtgaac gaagcactcg ataccaaaat ggaaaattta cagaacatga
    18121 cgtatctgat tgcctttaat cctgaaattg gggagttttg gaaaggacgg acgctggctg
    18181 atggtcacgc gggtcatacg agtagtgtaa tgccagaaaa tcagggggag cgagccaaga
    18241 aacctctcct taaccaggct cccggctcca agcaggttgt aagttccgta caggagcagg
    18301 ataccttgta tgaaatgaag caatttttgc agggttttac cacgttatat cctgaaattg
    18361 ccgggattct gatcgtgaac gaaaaaggag attatatcag caatgaaatg tatgctcgaa
    18421 gcacacgcag tctgacggaa gaagactggt acgcacaggc ggcgcagcat gcagggatat
    18481 tcactgtgct gggacagcca agtcaccgta atgtgaccac tcatgtccgg tacaaggaca
    18541 gtgaaattgt ctctgtcgtc cgttcggtca cggattcgga gacaggacat gtactgggtg
    18601 taattatgat tgatctcaag ctgcgggctg tgtcgcaagc tgccagagat gtaaccttgg
    18661 gcaaaagcgg gtatgtcatg gtgacagatg ccaagggacg cagtgtatat atgccagata
    18721 tgcctttgat tgagcgcatt ccgtcgcaat ggttcgggcc agaggatagc gggatgttta
    18781 cccgtgaagc cggaggcagg gaattgctgt tcatgttcca ggcttccgag ttcacgggct
    18841 ggagaaccgt gggagtattc ccggcacgcg aatctacact ggaagtgcgg caaattcagt
    18901 tctacgttgt ctgttttgtt ttcattgtat gtctgtttgg cttaacggca tccttgcgat
    18961 tgtccagttc tatcgcgcag ccaattttcc ggcttatgtc ttatatgcgt acggcagaga
    19021 cgggggatct tacggttcgc caatggagtg agcgcgggga tgaaatcgga atgctgggcc
    19081 ggagctttaa ccggatgctg gagcaaatcc gccgtctcat gtcgcttagc gaactgaggg
    19141 aacgacaaaa acgggatgcc gaactacgca gtcttcaaga gcatattaag ccgcattttc
    19201 tatacaatac gctagatacc attcattgga tggcccgaaa aaatggagca gacgacgtat
    19261 ccgatatggt gggggcgtta tcgagattgt tccgccttgg actgagcaaa ggggatgact
    19321 ttattccgct acgctctgag attgagcata tctcaagcta tatgcaaatc cagcaaaccc
    19381 gttatcgtga ccgacttcgc tgggaattaa atgtacccga cgggctaaag gatctgtttg
    19441 tgttgaagct tatgcttcag cctgtggtgg aaaatgcgat ttaccacggc attaaggcca
    19501 gacgtggtcc aggcacgatt tgcgtagaag ctaaagccga ggacggcaag ctgctgctga
    19561 cggtacgtga cgacggtgca gggatgacgg cggagcgtct gtgtgagctg cgtgaatggc
    19621 tggaaatacc gctggaggcg atggaaggaa gacggaaaca aaaggaagtt cgtacaaatg
    19681 gcagaagcta cggcatgttg aatgtacaag cgcgtatccg attgtctttt ggcgaggaat
    19741 atggaattac attggacagt aaagaaggga caggtacctg cgttacaatc actcatccgt
    19801 tgctgctgga tatggcgcaa ctgaagaagc cttatgacaa aggagagggt caggatgacg
    19861 aaatccaagg gaacagacaa cgcgacaacg gcgagtctga ttgaccaagc cataccagaa
    19921 gtgacgatag ggacggctaa acgttatcaa gtattgatcg cagatgatga gccgatcatc
    19981 cgtgagggga ttcgggactg cctagactgg acggctctgg gcatggaggt tgtagcagag
    20041 gcagaggacg gtgaagaagc gctgaagctg gttggtcagc ttagcatcga catcgtgctg
    20101 gtcgatatga atatgccatt catggatgga attgaactga ttcggcggct gcgggaagga
    20161 cgctcggagt gccgttgcct gatcatttcc gggcatgatg aatttgctta tgcacaggaa
    20221 gctgtacggc ttggcgt
//
