LOCUS       NZ_LJIW01000002        22092 bp    DNA     linear   CON 11-JUN-2024
DEFINITION  Streptomyces malaysiensis strain F913 SMF9132, whole genome shotgun
            sequence.
ACCESSION   NZ_LJIW01000002
VERSION     NZ_LJIW01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces malaysiensis
  ORGANISM  Streptomyces malaysiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
REFERENCE   1  (bases 1 to 5400668)
  AUTHORS   Xu,Y., Wei,J., Xie,J., Li,T. and Zhou,Z.
  TITLE     Genome sequence, genome mining and natural product profiling of a
            biocontrol bacterium Streptomyces malaysiensis F913
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5400668)
  AUTHORS   Xu,Y., Wei,J., Xie,J., Li,T. and Zhou,Z.
  TITLE     Genome sequence, genome mining and natural product profiling of a
            biocontrol bacterium Streptomyces malaysiensis F913
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 5400668)
  AUTHORS   Li,T. and Zhou,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) State Key Laboratory of Silkworm Genome
            Biology, Southwest University, Tian Sheng Road, Beibei, Chongqing,
            Chongqing 400715, China
REFERENCE   4  (bases 1 to 5400668)
  AUTHORS   Li,T. and Zhou,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) State Key Laboratory of Silkworm Genome
            Biology, Southwest University, Tian Sheng Road, Beibei, Chongqing,
            Chongqing 400715, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-FEB-2015
            Assembly Method                   :: SOAPdenovo v. 2.04
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891865.1-RS_2024_06_11
            Annotation Date                   :: 06/11/2024 05:20:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,419
            CDSs (total)                      :: 9,336
            Genes (coding)                    :: 9,091
            CDSs (with protein)               :: 9,091
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 59 of 245
            Pseudo Genes (incomplete)         :: 218 of 245
            Pseudo Genes (internal stop)      :: 14 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:22:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2160779
            Orig. end                         :: 2182871
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJIW01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22092
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="12"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22092
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22092
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12092](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12092)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            132..467
                     /locus_tag="SMF913_RS33510"
                     /old_locus_tag="SMF913_26609"
     CDS             132..467
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056920.1"
                     /locus_tag="SMF913_RS33510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26609"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_079259937.1"
                     /transl_table=11
                     /translation="MEKQPYVCGLDAAVDVIDGKWKVLIIWALNHQRCRFGELKRLVPG
                     VSEKVLTQQLRELAADGIVHRESYDVVPPKVEYSLTGLGEELNTALRPLGAWGKRRMAT
                     LAETGRG"
     misc_feature    complement(532..543)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.39"
                     /tool="antismash"
     gene            600..1940
                     /locus_tag="SMF913_RS33515"
                     /old_locus_tag="SMF913_26610"
     CDS             600..1940
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056919.1"
                     /locus_tag="SMF913_RS33515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26610"
                     /product="MFS transporter"
                     /protein_id="WP_102936573.1"
                     /transl_table=11
                     /translation="MTDSAPRSQPRTPWRAVFGGSIGNLVEWYDWFVYASFATYFAGAF
                     FPKGNDTAQLLNTAGIFAVGFFMRPVGGWLLGRFADRRGRKAALTLTVSLMSASALLIA
                     IAPTYDQVGYFGAGVLLVARLLQGLSVGGEYAASATYLTEASRPGGRGFVSSFQYVSMT
                     MGQLIGLGLQIVLQHTMSDDALHSYGWRIPFIVGAVGAAVVFWLRRNLLETEIYAEEDA
                     RQDQERGTIAELLRHRKEAALVIALTMGGTVAYYTYTTYLTKYLSNTAGMSKSDASLVS
                     FCALFLFMLLQPLAGALSDRIGRRPLLITFGFGSMLGTVPIMTALSHADTFTGALLLSL
                     AALVIVTGYTSINAVVKAELFPTHVRALGVALPYALANALFGGTAEYVALWFKKGGVES
                     RYYWYVSACAAVSLIVYLTMRETRDAALSRDRADGPAAPGKQRTTAV"
     gene            complement(1965..2432)
                     /locus_tag="SMF913_RS33520"
                     /old_locus_tag="SMF913_26611"
     CDS             complement(1965..2432)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056918.1"
                     /locus_tag="SMF913_RS33520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26611"
                     /product="ATP-binding protein"
                     /protein_id="WP_069860415.1"
                     /transl_table=11
                     /translation="MAVALRQRSTMAHHPSPGSVDSALRQERFQLPARGASVAIARHRV
                     RSRVPEWGFHEDLCDAAELVMSELFTNALVHTGSEQILCVLRAHERRMLYVEVADQGGG
                     PAVPTPREAGLEDECGRGLALVRALADAWGDRPGVDGGRVVWAQMSVAVGR"
     misc_feature    complement(2567..2579)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            2658..3515
                     /locus_tag="SMF913_RS33525"
                     /old_locus_tag="SMF913_26612"
     CDS             2658..3515
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712676.1"
                     /locus_tag="SMF913_RS33525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26612"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_069860414.1"
                     /transl_table=11
                     /translation="MGEARSAPTVGQMVLGMRLRDLREKAGVNYDQAARALHVNQTTVR
                     RMEKAEVGLKLPYVEKLLQTYGADQEEIDSFLALAEEANRPGWWHRFRDVLPDWFSLYV
                     SLEGAASRIRAYEPHFVPGLLQTEDYARTLLSIGFPHGSDRELERRVALRMERQELLHR
                     PNGPHLWVVMDETVLRLAIGGPEVMRAQVDHLIEAAQRPNVTLQVVPFSAGPHPGMGGP
                     FQLFRFQIPELPDIVYAEGLTGAGYLDQRSDVVAYLEALDRMGTQATPARRTESFLRGI
                     RKEL"
     gene            3518..3814
                     /locus_tag="SMF913_RS33530"
                     /old_locus_tag="SMF913_26613"
     CDS             3518..3814
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542876.1"
                     /locus_tag="SMF913_RS33530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26613"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_069860413.1"
                     /transl_table=11
                     /translation="MDQVDVYNGMPAKQLAIEGWAKPWSGPNGGACVEALRLKDGRVAL
                     RQSTDPDGPALIYTHHEIERFIQGAKAGAADFLLTRPENLTTSAGSAPERRAA"
     gene            3811..4629
                     /locus_tag="SMF913_RS33535"
                     /old_locus_tag="SMF913_26614"
     CDS             3811..4629
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056915.1"
                     /locus_tag="SMF913_RS33535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26614"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_102936574.1"
                     /transl_table=11
                     /translation="MTDYGLAPDQIDTTKPHPARMYDFYLNGKDHYEVDAEAAGRVLEV
                     YPTVRLNATVNRGFIHRATRWLAREAGVRQFLDIGTGIPTEPNLHQVAQGVIPEARVVY
                     TDYDPIVLAYAQALLIGTPEGRTAYVQSDVRDPERIMSAPELHETLDLTQPVAISVNAL
                     FHFIPEEDKPYEIVRKLMEPLVPGSYLMLTHSTHDFSEETWRNVIQVYKESGISFTTRS
                     QSEVGAFFDGLELIDPGVSEPHQWKPDPGDRPETIRSADINMWAGVARKS"
     gene            complement(4654..6078)
                     /locus_tag="SMF913_RS33540"
                     /old_locus_tag="SMF913_26615"
     CDS             complement(4654..6078)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056914.1"
                     /locus_tag="SMF913_RS33540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26615"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_102936575.1"
                     /transl_table=11
                     /translation="MVRLPRLRRRRPSLRTTFALSFSAAATVVTLLVGGLSYDAAAGLV
                     RVDQQSAFDDVIHDLRGQVRGDKVVLRQYPTESTGPVPYDLRDDLRRISRMDVQVINGR
                     GTVYDAGKPPLPVTDEDRTTAAAHTAGTVVRREIDIGGEQYRMATVAVGDGTGAVQVAQ
                     QISDTEDLLQELQQRTALFVVAVILAAGLAGWWLAGRITRRLVRLTRVAESVAATGRME
                     VAVPVAGDDEVGRLGRAFDGMLGQLARSKDDQRRLVQDAGHELRTPLTSLRTNISLLRR
                     FEDLPGPAREDLLADLAGETRELTDLVNELVDLAAGQRDDEPRTEVSLEEVATTAVTLA
                     RRRTGREITVRASGDTRLTGHPATLQRAISNLVENAAKFDQDGTGPVEVMISGRRVEVL
                     DRGPGIAAEDRERVFDRFYRAPGARSLPGSGLGLAIVREVALAHGGTVFARPRPGGGAI
                     LGFTVGAGTGAIGTGP"
     gene            complement(6078..6782)
                     /locus_tag="SMF913_RS33545"
                     /old_locus_tag="SMF913_26616"
     CDS             complement(6078..6782)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056913.1"
                     /locus_tag="SMF913_RS33545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26616"
                     /product="response regulator transcription factor"
                     /protein_id="WP_102936576.1"
                     /transl_table=11
                     /translation="MTNTVLLAEDDRAIRQALERALTLEGYRVTGVPDGIEALAAIHRE
                     RPDVVVLDVMMPGVDGLQVCRVLRAEGDRTPILMLTARVETADRIEGLDAGADDYVAKP
                     FEVEEVFARLRALLRRAAPAEPAAPEDTAIDGVLEVSDLRLDSSARRVWRGGTELELTR
                     TEFDLLELLARNAGIVLDHATIYARIWGYDFGPGSKNLAVYIGYLRRKVDPEGRAPLIH
                     TVRGVGYTLREE"
     misc_feature    6853..6868
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            6958..8223
                     /locus_tag="SMF913_RS33550"
                     /old_locus_tag="SMF913_26617"
     CDS             6958..8223
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056912.1"
                     /locus_tag="SMF913_RS33550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26617"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_102936577.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.5e-37,
                     bitscore: 126.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAFLLHNAYGIGGTIRTTMNLATALADRHEVEIVSMMRHRETP
                     RFALDPRVRLVPLVDTRPNGADAKDPLFFEASRDFPAAEKRHHQYNRLIDTRAAEYLRD
                     CPADVIVGTRPGVNVYISRFAPRRALRIAQEHLRYEAHSKKLRAELAPFYRSLDAVVTT
                     TEADAAVYREKMPMPGVRTLAIPNSVPEPAVAPSEGTAPVIAAAGRLVRGKRFDLLIDA
                     FAEVSEKYPDWRLRIYGGGAEKERLAEHIERLGLSGSAELMGSYSPIEAEFAKASLVAV
                     ASDAESFGMTIVEAMRCGVPVVSTDCPLGPAEIIRDGVTGRLVPTGDKHALASALMELM
                     ADAPARRAMGAAALEGSRIYDPAPIARRYDQLFEELRTSRFARGWERYRTAARARWRRL
                     ARRFGIAPGRRRTPAAGEKASA"
     gene            complement(8432..9910)
                     /locus_tag="SMF913_RS33560"
                     /old_locus_tag="SMF913_26619"
     CDS             complement(8432..9910)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017947291.1"
                     /locus_tag="SMF913_RS33560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26619"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_069860408.1"
                     /transl_table=11
                     /translation="MTVTDEGRAERATAEGPGIDPERLATCLSVLAELDRLPVDHPDAI
                     TVRRATSGIYRSVKQRRRQERRAAKTANDKAVTEATATGAADRIDDETLGLALTSSVST
                     EIAGILARPRSCYVCKTRYVEVDAFYHQLCRDCAAENRARRDARTDLTGRRALLTGGRA
                     KIGMYIALRLLRDGAHTTVTTRFPGDAVRRFKAMPDSAEWLHRLKVVGIDLRDPAQVIA
                     LTDEVSAAGPLDILINNAAQTVRRTPQAYAELIAGESAPPPAGELPESLVLGAFGSGAQ
                     AALPGPRAARDGALTPQDLTALALTSGSASPARIEAGTAIDAGGLVPDLDPTNTWVQRV
                     DEVDPVELLEVQLCNETAPFILVSRLRPAMAASPARRKYVVNVSAMEGKFGRGYKGAGH
                     PHTNMAKAALNMLTRTSAREMFEADSILMTSVDTGWITDERPHPEKIRLAAEGFHAPLD
                     LVDGAARVYDPIVRGEAGEDLFGCFLKDYAPTSW"
     gene            complement(10001..11107)
                     /gene="pqqE"
                     /locus_tag="SMF913_RS33565"
                     /old_locus_tag="SMF913_26620"
     CDS             complement(10001..11107)
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056910.1"
                     /locus_tag="SMF913_RS33565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26620"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_102936578.1"
                     /sec_met_domain="PF04055 (E-value: 2.7e-21, bitscore: 74.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-06, bitscore: 25.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-06, bitscore: 26.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.5e-08, bitscore:
                     31.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAPRPWALLAELTHGCPLHCPYCSNPLELVRRSRELSTAEWTE
                     VMRQAGEFGVVHTHLSGGEPLLRGDLAEIVTAAESAGIYTQLVTSGVGLDGARLTALTA
                     AGLRSVQLSVQHADPAAADRIAGHRAFAAKERAAALVRAAGLPLGLNVVLHRDNLDALD
                     ALIRRGVDWGADRIELANTQFYGWALRNRDALLPTRDQLARARETVQRWRDRLGGATDL
                     VWVVPDYFDGVAKPCMGGWGAVSLTVAPDGTALPCPAAASLPDLDPPNVRDHSLEWIWD
                     HSGAFNRYRGEGWMREPCRTCSRRAEDFGGCRCQAYALTGDAARTDPACALSPDHGVIR
                     ALTDTGHPAAAATPAPTGGYAYRKPGGG"
     gene            complement(11104..11388)
                     /gene="pqqD"
                     /locus_tag="SMF913_RS33570"
                     /old_locus_tag="SMF913_26621"
     CDS             complement(11104..11388)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056909.1"
                     /locus_tag="SMF913_RS33570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26621"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_102936579.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-18, bitscore:
                     64.7, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9e-12, bitscore: 43.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAAGTPPAPAGWRPALAPAVSLRHDRVRDADLLVLPERVVVLRG
                     SAARILRLCDGDRDLDTIVAELESRFPGAPVADDVRAFLGRMRGEGWVR"
     aSDomain        complement(11110..11349)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SMF913_RS33570_PqqD_RRE.1"
                     /evalue="7.50E-21"
                     /identifier="RREFam006.1"
                     /label="SMF913_RS33570"
                     /locus_tag="SMF913_RS33570"
                     /protein_end="93"
                     /protein_start="13"
                     /score="64.7"
                     /tool="antismash"
                     /translation="RPALAPAVSLRHDRVRDADLLVLPERVVVLRGSAARILRLCDGDR
                     DLDTIVAELESRFPGAPVADDVRAFLGRMRGEGWV"
     gene            complement(11385..12092)
                     /gene="pqqC"
                     /locus_tag="SMF913_RS33575"
                     /old_locus_tag="SMF913_26622"
     CDS             complement(11385..12092)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056908.1"
                     /locus_tag="SMF913_RS33575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26622"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_102936580.1"
                     /sec_met_domain="TIGR02111 (E-value: 3.6e-83, bitscore:
                     276.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRTRLEERLRAVAQERYHDRHPFNVRMHAGELTPAELRRWIL
                     NRFHYQRHIPVKDALITAKFDTPRLRRMWLRRIQDHDGTTEGEGGIERWLRLGEAAGLH
                     RDRLLSAEEVVPGVRLAVDGYVNFCRLRGPLEAVAASLTELSAPGIMLTRIDAFERYYP
                     WIEREGLTYFRNRVDQGRRDSTEALDAVLTWARTPEDEDRAVAALAFKCDVLWSLLDAV
                     DHADTKDGPGEGT"
     gene            complement(12089..12988)
                     /gene="pqqB"
                     /locus_tag="SMF913_RS33580"
                     /old_locus_tag="SMF913_26623"
     CDS             complement(12089..12988)
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669247.1"
                     /locus_tag="SMF913_RS33580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26623"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_102936581.1"
                     /transl_table=11
                     /translation="MRVRVLGTAAGGGVPQWNCACPGCSGARAHPGWRRRHASLAVQAA
                     EGRWYLVNATPDLGDQVEDHPELHPGPEPRRTPLAGVILTDAELDHTLGIARLREADGI
                     EIVATAQVRHALLTGLHLGEVLTPYARLDWRPLGPEDRPLAEDSPLVIGAVPVSAKRPR
                     YAAGLDAPDDGGWVVALRLTDRTTGRSLLYAPALAAWSDTFQRAAESADHVIVDGTFWS
                     DDEPLSSGFGSRTATAMGHLPIDGPDGTARRLAALEGRTLYTHLNNTNPLNDPAAPHHT
                     ELRKLGVEVAADGMVIDL"
     gene            complement(13000..13143)
                     /gene="pqqA"
                     /locus_tag="SMF913_RS33585"
                     /old_locus_tag="SMF913_26624"
     CDS             complement(13000..13143)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_093467075.1"
                     /locus_tag="SMF913_RS33585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26624"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_093702705.1"
                     /transl_table=11
                     /translation="MNDTTPRTAPEATDRTRTDAGQTAWQTPDYVVVETALEVTAYSLN
                     AR"
     misc_feature    13310..13326
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.36"
                     /tool="antismash"
     gene            13543..14622
                     /locus_tag="SMF913_RS33590"
                     /old_locus_tag="SMF913_26625"
     CDS             13543..14622
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712691.1"
                     /locus_tag="SMF913_RS33590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26625"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_102936582.1"
                     /transl_table=11
                     /translation="MKRYRNTAAAAAATALAAGLLIGTAGTGTAAPGRADSAPSDIKTV
                     SSGWTVPWGLSWLPDGSALITERDSYLVYKLTQSGTRTEVGTVPNVVTTDGEGGLLGIA
                     VSPNWNSDHTIYLMHTASEGNRIARMTYDGSSLGGYQTLVTGIKKNKYHNGGRLKFGPD
                     GYLYATTGEAQTPDLSQDKNSLNGKILRMTTDGKPAPGNPFGTLVYSYGHRNPQGITWD
                     PQGRLWEAEFGDSKYDELNLIEAGKNYGWPICEGECSTAGMTGPKRQWPTGDASPSGVT
                     YADGAMYLAALRGERLWRIPVDGTNAGTPKAYYTSSYGRLRTVETVPGKNTLWLSTTNA
                     DSNGGEPDGADKVFQVELK"
     gene            complement(14685..15830)
                     /locus_tag="SMF913_RS33595"
                     /old_locus_tag="SMF913_26626"
     CDS             complement(14685..15830)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712692.1"
                     /locus_tag="SMF913_RS33595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26626"
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="WP_079259928.1"
                     /transl_table=11
                     /translation="MISRRTLFASTLGLTGGLLLPTAGAGAAPADWSRAVVDSTIARRP
                     DPASLGGWGYIQGLFLLGTYRVHQRVDEPSYLAYIKRWVDNFVDADGHMSRTFDNLDAM
                     QAGNLLLILHQETGDPRYRTAAGQIRARITTYPRTADGGMWHATGRTNELWGDGVFMAQ
                     PFLLRYGIAYGDQEYAYEEVTRNLSVYFRHLKAANGLIYHGYDADGDAPWKPDPTTGTS
                     AHFWARAIGWTAMTHVEVLELLPADHPRRAELIDNVRHLAKGFARYQDPATGRWFQVVD
                     KASEPGNWTETSASSMYTLMLHAALEHGWISGGGYTEAVRRGYEGVLRKVSVGSDGLTN
                     ITDISEGTNVGDLAYYLGRARNTNDLHGLGAFLLMNERLAH"
     misc_feature    complement(15800..15815)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.49"
                     /tool="antismash"
     misc_feature    complement(15968..15986)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.03"
                     /tool="antismash"
     gene            16003..17028
                     /locus_tag="SMF913_RS33600"
                     /old_locus_tag="SMF913_26627"
     CDS             16003..17028
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056895.1"
                     /locus_tag="SMF913_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26627"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_102936583.1"
                     /transl_table=11
                     /translation="MGPLRLFPLLSAVLAATVLTGCGSSDPASSSASSGSSGSSGSSGS
                     SAVSKAPGSSAADGDFPRTVAHEQGSTPLKAAPKRIAAISTGQLDDLLTLGVVPVATTR
                     ADYAGLVPGYLRTAFPGQAEALGSMTDIGTRTSPNLEKLAAAKPDLILVNSTQGALYPS
                     LAAIAPTVVTKGRGVNWKKDLLTVADAVGRRERARTLLTRFEKDAADQGEKLGGEHTAL
                     SMVRFNPDRVRMFGKKSFTGTIADDMGLGRPESQRFDDISQDLSGERIPRMDGDWIFYS
                     VQGRPGKTDAATYLSNPLWKKLGAVRGGHIAKVDDDPWYLNAGPTAARVVLRDITEHLG
                     R"
     gene            17299..18657
                     /locus_tag="SMF913_RS33605"
                     /old_locus_tag="SMF913_26628"
     CDS             17299..18657
                     /EC_number="6.3.1.-"
                     /GO_function="GO:0004356 - glutamine synthetase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056894.1"
                     /locus_tag="SMF913_RS33605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26628"
                     /product="glutamine synthetase family protein"
                     /protein_id="WP_102936584.1"
                     /transl_table=11
                     /translation="MGTGDREQAYARARQEAERLTANGIQGIALTWVDNAGLTRVKSVP
                     TARLPQAARRGVGMSPVFDVYLVDDSMTTSRHVGGPDGDLRLLPDLERLTPLAAQPGWA
                     WAPVDRYDQEGRAHPVCQRLFARRMAERARERGLAVRMGFETEWVVTTGDPDQDPPHYP
                     TTGPAYGMARLVDLADYLADLLGTLDAQHTEVHQLHPEYSPGQFEVSLAPTDPVAAADL
                     AVLVRETIRACSGRAGLNPMFGPVVDPGGVGNGAHLHLSLWQGDRNLCRDGDGPHAMTA
                     TAEAFLAGVLRELPALLAIGAPSPASYLRLEPSRWAGAYQCWGLENREAAVRFITGAPD
                     DPGAANAEIKSFDPAANPYLVAGAVIAAGLGGLDAGLSLPPPVSGDPAVEGRERRLPTS
                     LLTALEHFEDSTVLREALGDPLFESIAAVRRAEAALFEKSSPREIAIATRRRY"
     gene            18661..19830
                     /locus_tag="SMF913_RS33610"
                     /old_locus_tag="SMF913_26629"
     CDS             18661..19830
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056893.1"
                     /locus_tag="SMF913_RS33610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26629"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_102936585.1"
                     /transl_table=11
                     /translation="MEAAEQTDPTEPPLPPLVDHHCHGVVRSELGSAAFEAFLTESDAP
                     AALGTTFFDSQLGFAVRRWCPPLLGLEPHCPPAYYLARRRELGAREVARRLLSATGISE
                     FLVDTGLPGNLTTPQELALAAGGTAHEIVRLEQLAERIADTSLTADDFLTGVADGIREA
                     ARTAAGFKSVAAYRYGLDFEPDPPGPGAVHTAAERWLARRGQGGTAAARVTDPVLLRHL
                     LWSAAYTGLPLQLHTGFGDPDLRLDRCDPLALTDFVRAVRPTGCTLILLHGYPYHRGAA
                     YLAAVFPHVYADVRLALSHTGARAGAVLAEMLELAPFGKVLFSTDAYGLPELYVVGARL
                     FREALTGLLTHWVAEGAWSRRDARRVAALLGADNARRVYGLGTPTPRAG"
     gene            complement(20001..20783)
                     /locus_tag="SMF913_RS33615"
                     /old_locus_tag="SMF913_26630"
     CDS             complement(20001..20783)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029963.1"
                     /locus_tag="SMF913_RS33615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26630"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_093707527.1"
                     /transl_table=11
                     /translation="MRVRRLGWAGVEIEAGGRRLVVDYVRDLSPLFTGWKPGEGLAEPS
                     GKATAALVTHLHRDHTDASALADALTPGAPVLRPAPGHGDDVDNVTTLPAERELALHRL
                     AAEVVDAWSTREIGPFRVTAVPSVDGLGDPQLNWVVQADGQRVFHGGDTMFHGYWWLIA
                     RRFSPFDAVFLPANGAVVDAPHLQPPSPLPAALDPRQAAAAAEILDARYAVPIHYEPEQ
                     PDKIAGYVEVADPEKEFRTHAGRRAHVLAVGEWLDLAT"
     gene            20877..21479
                     /locus_tag="SMF913_RS33620"
                     /old_locus_tag="SMF913_26631"
     CDS             20877..21479
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054208.1"
                     /locus_tag="SMF913_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_26631"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_100805402.1"
                     /transl_table=11
                     /translation="MSPRRSAAEAQATRGRILGRAAEIASEEGLDGITIGRLAEELEMS
                     KSGVHKHFGTKETLQISTLDKAFVDFWHRVVEPTLTEPPGLRRLRAVCANSVGYLEAPL
                     LPGGCLMTAALTEYDGRPGRVRDAVAEVWSRWREQLRADLTAAVENGELPAGFDIDQAL
                     FEIIAAGLALNAAMQLQHDRAAAGRARRAIERALAQP"
     misc_feature    21952..21971
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.8"
                     /tool="antismash"
ORIGIN
        1 cattgctcca gttgttccga taccgctttg tcgtaggggt ccggcgcgcc gatcacagac
       61 tccttcctcg gcggtaatgt ggacaagtac gcactaaaaa gtgcgtactt accttgaggt
      121 cagtgggggc catggaaaag cagccctatg tctgcggtct ggacgcggcc gtggatgtga
      181 tcgacggcaa gtggaaagtg ctgatcattt gggcgctcaa tcaccagcgg tgccgtttcg
      241 gggaattgaa gcggcttgtt cccggtgtga gtgaaaaggt gctgacacag cagctgaggg
      301 agttggcggc ggacggaatc gtccaccggg agagctacga cgtggtgccg ccgaaggtgg
      361 agtattcgct gaccgggctg ggcgaggagc tgaatacggc gctgcgcccg ctgggcgcct
      421 ggggcaagcg ccggatggcg acactggcgg agaccggccg gggctgagcg ctccgccgga
      481 cgccgggccg ctcggcccga gaaggtcacc cgggggcgcg accccgccgc ggaatccctt
      541 ttccaactgg ccctgtgcgg ggtaggggtg agggatcacc ccgctcactt ggaggccccg
      601 tgaccgacag cgctccccgg agccaaccac gcacgccctg gcgagccgtg ttcggcggct
      661 cgatcggaaa tctcgtcgag tggtacgact ggttcgtcta cgccagtttc gccacctact
      721 tcgccggagc cttcttcccc aagggcaacg acaccgcaca gctcctcaac accgccggga
      781 tcttcgcggt cgggttcttc atgcgtcccg tcggcggctg gctgctgggc cggttcgccg
      841 accggcgcgg ccgtaaggcg gcgctcaccc tgacggtgtc gctgatgtcg gccagcgcgc
      901 tgctcatcgc catcgccccg acctatgacc aggtcggcta cttcggcgcg ggggtgctgc
      961 tggtggcgcg gctgctccag ggcctgtcgg tgggcggtga gtacgcggcc agcgccacct
     1021 atctcaccga ggcgtcccgg cccggcggcc ggggcttcgt ctccagcttc cagtacgtgt
     1081 cgatgacgat gggtcagctg atcggcctcg gtctccagat cgtgctccag cacaccatgt
     1141 ccgatgacgc gctgcactcc tacggctggc gcattccgtt catcgtcggc gccgtgggcg
     1201 cggccgtggt cttctggctg cggcgcaatc tgctggagac cgagatctac gccgaggagg
     1261 acgcccgcca ggaccaggag cgggggacca tcgccgagct gctgcgccac cgcaaggagg
     1321 cggcgctcgt catcgcgctg accatgggcg gcacggtcgc gtactacacg tacaccacct
     1381 atctgaccaa gtacctgtcg aacacggccg gaatgagcaa gtccgacgca tcgctggtca
     1441 gcttctgtgc cctgttcctg ttcatgctgt tgcagccgct ggccggggcg ctctcggacc
     1501 ggatcggccg ccgtccgctg ctgatcacct tcggcttcgg ctcgatgctc ggcaccgtgc
     1561 ccatcatgac cgcgctctca cacgccgaca ccttcaccgg ggcgctgctg ctctcgctcg
     1621 cggcgctggt catcgtcacc ggctacacgt cgatcaacgc ggtggtgaag gcggagctgt
     1681 tccccaccca tgtccgggcg ctcggggtgg ccctgccgta cgcgctggcg aacgcgctgt
     1741 tcggcggcac cgccgagtat gtggcgctgt ggttcaagaa gggcggtgtg gagtccaggt
     1801 actactggta cgtctcggcg tgtgcggccg tctcgctcat cgtctacctc accatgcggg
     1861 agacccgcga cgccgccctc tcccgggacc gcgccgatgg cccggccgcc ccggggaagc
     1921 agcggacgac ggcggtgtga cgggggcggc gggccggatc cgggtcagcg gccgacggcc
     1981 acgctcatct gggcccagac cacccgtccg ccgtccacgc ccggcctgtc cccccacgcg
     2041 tcggccaggg cgcggaccag tgccagtccg cgtccgcact catcctcaag accggcctcc
     2101 cgcggcgtgg ggacggccgg tccgccgccc tggtcggcga cctcgacata gagcatgcgc
     2161 cgctcatggg cgcgcagcac acagaggatc tgctcgcttc cggtgtgcac cagggcgttg
     2221 gtgaacagct cggacatcac cagctcggcg gcgtcgcaga gatcctcgtg gaagccccac
     2281 tccggtacgc gcgagcggac ccggtgccgg gcgatggcga ccgacgcgcc tctggcgggc
     2341 agctggaacc tctcctggcg gagggcggag tcaacgctcc cggggctcgg gtggtgggcc
     2401 atcgtcgagc gctgacgcaa tgccacggcc atgtgccttc cgtccgtcta cctgtggggg
     2461 cgtgaatgcc gtacgtgaat gccgcaagtg cgcgacacag cagtcacgtt ggaccggtca
     2521 cacccgtcac tatcgttgct gcgagcatca gttggcaagg cgcgatctgc aaaatgcaga
     2581 atagccagcg cactctgttg ccctcacctc gcacgtggca cactgattcc tgacaagacc
     2641 gtcccaggag gtacgacgtg ggtgaagcgc gatctgcccc gaccgtcggg cagatggtcc
     2701 tcggcatgcg gctgcgggac cttcgcgaga aagccggcgt caactacgac caggctgcca
     2761 gggcgctgca cgtcaaccag accacggtgc gcaggatgga gaaggccgaa gtcggcctga
     2821 aactgcccta cgtcgagaag ctgctgcaaa cctatggcgc cgaccaggaa gagatcgact
     2881 ccttcctcgc actcgccgag gaggccaaca ggcccggctg gtggcaccgg ttccgtgatg
     2941 tgctgccgga ctggttcagt ctctatgtga gcctcgaggg cgcggccagc cgtatccgcg
     3001 cctacgagcc gcacttcgtc cccgggctgc ttcagaccga ggactacgcc cgcacgctcc
     3061 tctccatcgg cttcccgcac gggtccgacc gggagctcga gcgccgggtg gccctgcgga
     3121 tggagcgcca ggagctgctc caccgcccga acggaccaca tctgtgggtc gtgatggacg
     3181 agacggtgct ccgtctggcc atcggcggcc ccgaggtgat gcgcgcccag gtggaccatc
     3241 tgatcgaggc cgcgcaaaga ccgaacgtca cccttcaggt ggtgccgttc tccgccggcc
     3301 cgcacccggg catgggcggc cccttccagc tcttccggtt ccagatcccg gaactgccgg
     3361 acatcgtcta tgccgagggc ctgaccggcg ccggctatct cgaccaacgt tccgatgtgg
     3421 tcgcgtatct ggaggccctg gaccgcatgg gcacccaggc cacaccggcg cggcgcacgg
     3481 agagctttct ccgtgggatt cgcaaggagc tctgactgtg gatcaggtag atgtgtacaa
     3541 cggcatgccg gccaaacagc tggcgatcga aggctgggcc aagccctgga gcggccccaa
     3601 cggcggtgcc tgtgtggagg ccctgcggct gaaggacggg cgggtcgccc tgcgtcagtc
     3661 gaccgatccg gacggccctg ccctgatcta cacccaccat gaaatcgaga ggttcatcca
     3721 gggcgccaag gccggcgccg cggacttcct gctcacacgc ccagaaaacc tgaccacctc
     3781 ggcgggttcc gcaccggaac ggagggccgc gtgaccgact acgggctcgc ccctgaccag
     3841 atcgacacca ccaagccgca cccggctcgg atgtacgact tctacctcaa cggcaaggac
     3901 cactacgagg tcgacgcgga ggccgccgga cgggtgctgg aggtctatcc gaccgtccgg
     3961 ctcaacgcga ccgtcaaccg gggcttcatc caccgcgcca cccgctggct ggcccgggag
     4021 gccggggtcc ggcagttcct cgacatcggc accgggatac ccaccgagcc caacctccac
     4081 caggtcgccc agggcgtcat cccggaggcc cgggtggtct acaccgacta cgaccccatc
     4141 gtgctggcct acgcccaggc gctgctcatc ggcacccccg agggccgtac ggcctatgtg
     4201 cagtcggatg tgcgcgaccc cgagcggatc atgagcgccc ccgagctgca cgagacgctg
     4261 gacctgaccc agccggtggc gatctcggtg aacgcgctct tccacttcat tccggaagag
     4321 gacaagccgt acgagatcgt ccgcaagctg atggagcctc tggtcccggg cagttatctg
     4381 atgctgaccc actccaccca tgacttctcg gaggagacct ggcggaacgt catccaggtc
     4441 tacaaggaga gcggaatctc cttcaccacc cgctcccaga gcgaggtcgg ggcgttcttc
     4501 gacggtctgg agctgatcga cccgggtgtg tcggagcccc accagtggaa gccggacccc
     4561 ggtgaccgcc cggagaccat ccgcagcgcg gacatcaaca tgtgggcggg agtggcccgg
     4621 aagtcctagg ggcccaggcc ccgggaccgg acctcacggc ccggtgccga tcgccccggt
     4681 gccggcgccg accgtgaagc ccagtatcgc gcccccgccc gggcgcggcc gggcgaagac
     4741 ggtgccgccg tgcgcgaggg cgacctcgcg cacgatggca agacccagcc cggaaccggg
     4801 caggctgcgc gccccggggg cgcggtagaa gcggtcgaag acccgctcgc ggtcctccgc
     4861 ggcgatgccc ggaccccggt ccagcacctc cacccggcgg ccgctgatca tcacctcgac
     4921 gggcccggtg ccgtcctgat cgaacttggc ggcgttctcc accagattgg agatcgcgcg
     4981 ctgaagggtg gccgggtggc ccgtcagacg ggtgtcgcca ctggcccgta cggtgatctc
     5041 gcggccggtc cggcgccggg cgagggtcac ggcggtggtg gccacctcct ccagcgagac
     5101 ctccgtacgg ggttcgtcgt cccgctgccc ggccgccaga tccaccagtt cattgacgag
     5161 gtcggtcagc tcccgggtct cccccgccag atcggccagc agatcctccc gcgcgggccc
     5221 cggcagatcc tcgaagcggc gcagcaggga gatattggtg cgcagcgagg tgagcggggt
     5281 gcgcagctca tgcccggcgt cctggaccag ccgccgctgg tcgtccttgg agcgcgcgag
     5341 ctgtccgagc atgccgtcga aggcccgtcc gaggcggccc acctcgtcgt ccccggcgac
     5401 cggcaccgcc acctccatcc ggccggtcgc ggccacgctc tcggcgaccc gggtcagccg
     5461 caccagccgc cgggtgatcc gcccggccag ccaccagccg gccagcccgg ccgcgaggat
     5521 gacggcgacc acgaagagcg cggtgcgctg ctggagctct tgcagcagat cctcggtgtc
     5581 gctgatctgc tgggccacct gaaccgcacc ggtgccgtcg cccacggcca ccgtggccat
     5641 gcggtactgc tccccgccga tgtcgatctc acgccgtacg acggtgccgg ccgtgtgggc
     5701 ggcggcggtc gtccggtcct cgtcggtcac cggcagcggg ggcttgcccg cgtcgtagac
     5761 cgtgccccgg ccgttgatca cctggacgtc catccggctg atccggcgca gatcgtcccg
     5821 caggtcgtac gggacgggcc cggtggactc ggtggggtac tgccgcagga ccaccttgtc
     5881 gccgcggacc tggccgcgca gatcgtggat gacgtcgtcg aacgccgact gctggtccac
     5941 ccgtaccagc ccggccgccg cgtcatagct gagaccgccg accaggaggg tgaccacggt
     6001 ggcggccgcc gagaacgaga gcgcgaaggt ggtccgcaga ctgggccgcc tgcggcggag
     6061 ccgtgggagc cgcaccatca ctcctcccgc agggtgtaac cgaccccgcg caccgtatgg
     6121 atcagcgggg cgcgcccctc cggatcgacc ttgcggcgca gatagccgat gtagacggcg
     6181 aggttcttcg aacccgggcc gaagtcatag ccccagatgc gggcgtagat cgtggcgtgg
     6241 tccaggacga tgcccgcgtt acgcgccagc agctccagca ggtcgaattc ggtacgggtc
     6301 agctccagct ccgtaccgcc gcgccagacc cgccgcgccg aggagtccag gcgcagatcc
     6361 gagacctcca gcaccccgtc gatggcggtg tcctccggcg cggccggttc ggcgggggcg
     6421 gcccggcgca gcagcgcgcg cagccgggcg aagacctcct cgacctcgaa gggcttggcc
     6481 acatagtcgt ccgcgccggc gtcgagaccc tcgatccggt cggcggtctc gacccgcgcg
     6541 gtgagcatga ggatgggggt gcggtcccct tcggcgcgca gcacccggca cacctggagc
     6601 ccgtccacgc ccggcatcat cacatccagg accaccacgt ccgggcgctc gcggtggatg
     6661 gccgccagcg cctcgatccc gtcgggcacg ccggtgacgc ggtacccctc cagggtcagg
     6721 gcgcgttcca gcgcctggcg gatggcacgg tcgtcctcgg cgagcagcac ggtgttggtc
     6781 acaccccgag tctgccaagg ccacagcggt gcccgtcgcg ggcgggggtc ccgagcggtg
     6841 cttcttaccc cgctctcacc ttcttcacgc gacgggctta ccggacctcg gcaaggtgtc
     6901 cgctatgttc cggggggaac tcgccccggg aatgcaaccg gccggagaaa ataccgcatg
     6961 aagatcgcat tcctgctgca caacgcctac gggatcggcg gaacgatccg gacgacgatg
     7021 aacctcgcga cggcgctcgc cgaccgtcac gaggtcgaga tcgtctcgat gatgcggcac
     7081 cgcgagacgc cgcgtttcgc cctcgacccc cgggtgcggc tggtccccct ggtggacacg
     7141 cgtccaaacg gcgcggacgc gaaggacccg ctgttcttcg aggccagccg ggacttcccg
     7201 gccgccgaga agcggcacca ccagtacaac cgcctgatcg acacacgggc cgcggagtat
     7261 ctgcgcgact gccccgccga tgtgatcgtc ggcactcggc cgggggtgaa cgtctacata
     7321 tcccgcttcg ccccccgccg tgccctgcgc atcgcccagg agcatctgcg gtacgaggcg
     7381 cacagcaaga agctgcgggc ggagctggcc ccgttctacc ggtcgctgga cgccgtggtc
     7441 accacgacgg aggcggacgc cgcggtctac cgcgagaaga tgccgatgcc gggggtgcgg
     7501 accctcgcga tacccaacag cgtccccgaa ccggccgtcg ccccctccga gggcaccgca
     7561 ccggtgatcg cggcggccgg gcggctggtc cgcggcaaac gcttcgacct gctgatcgac
     7621 gccttcgcgg aggtctcgga gaagtacccg gactggcggc tgcggatcta cggcgggggc
     7681 gcggagaagg agcggctggc ggagcacatc gagcggctgg gcctgtccgg gagcgcggag
     7741 ctgatggggt cctactcccc catcgaggcg gagttcgcga aggcgtcgct ggtcgcggtc
     7801 gcctcggacg ccgagtcgtt cgggatgacg atcgtggagg ccatgcgctg cggggtgccg
     7861 gtggtgagca ccgactgccc gctgggcccc gccgagatca tccgggacgg ggtcaccgga
     7921 cggctcgtcc ccaccgggga caagcacgcg ctggcgagcg ccctgatgga gctgatggcc
     7981 gacgccccgg cccggcgggc gatgggcgcg gccgccctgg agggctcccg gatctatgac
     8041 cccgcgccga tcgcccggcg ctacgaccag ctcttcgagg agctgcgcac gagccggttc
     8101 gcccgcggct gggagcgcta ccggaccgcc gcccgcgccc gctggcggcg cctggcccgc
     8161 cgcttcggca tcgcccccgg ccgccgccgc accccggcgg cgggcgagaa ggcgagcgcg
     8221 taaccccggg cggggccgcg tatccggcac ccgcgcgggt ggacggcgcc ccggccgagc
     8281 ggggcgcccg tcaggacgcc ggggagtacc cggaccccgg ggcgtacgcg gatgtcgggg
     8341 cgcacccgga caccggggcg tatccggatg tcggggcgca cccggatgtc ccggcttacc
     8401 aggaggtccc ggcttaccag gacgtccggg cttaccagga cgtcggggcg tagtccttca
     8461 ggaagcagcc gaagaggtcc tcgcccgcct cgccccggac gatcgggtcg tagacccgcg
     8521 ccgcgccgtc caccaggtcg agcggggcgt ggaagccctc ggccgccagc cgtatcttct
     8581 ccggatgcgg gcgctcgtcg gtgatccatc cggtgtcgac gctcgtcatc aggatggagt
     8641 cggcctcgaa catctcccgt gcgctggtgc gggtcagcat gttcagcgcg gccttggcca
     8701 tattggtgtg cggatggccc gcgcccttgt agccccgacc gaacttgccc tccatcgcgg
     8761 agacgttgac cacgtacttg cgccgggcgg gcgaggccgc catcgccggg cgcaaccggc
     8821 tcaccaggat gaacggcgcc gtctcattgc acagctggac ctccagcagc tcgaccgggt
     8881 ccacctcgtc aacccgctgc acccaggtgt tggtcgggtc cagatccggc accagcccgc
     8941 ccgcgtcgat cgcggtcccg gcctcgatcc gggccggtga ggcggagccg ctggtgaggg
     9001 cgagggcggt gaggtcctgc ggggtgaggg cgccgtcccg tgccgcgcgg gggcccggca
     9061 gggccgcctg ggcgccgctg ccgaaggcgc cgaggaccag ggactcgggg agctccccgg
     9121 cgggcggcgg cgccgactcg cccgctatca gctccgcgta cgcctggggt gtgcggcgga
     9181 cggtctgggc ggcgttgttg atcagtatgt ccagcgggcc cgcggcgctc acctcgtcgg
     9241 tcagcgcgat gacctgggcg gggtcacgca gatcgatacc gacgaccttg agccggtgca
     9301 gccactccgc gctgtccggc atggccttga agcggcggac ggcgtcgccg gggaagcggg
     9361 tggtgacggt ggtgtgcgcg ccgtcgcgca gcagccgcag cgcgatatac atcccgatct
     9421 tcgcgcggcc gccggtgagc agggcgcggc gcccggtgag atcggtgcgg gcgtcacggc
     9481 gggcccggtt ctcggcggcg cagtcgcggc acagctggtg gtagaaggcg tcgacctcga
     9541 cataccgggt cttgcagacg tagcaggagc gggggcgcgc caggatgccc gcgatctcgg
     9601 tgctgacgga gctggtgagc gcgaggccca gcgtctcgtc gtcgatccgg tccgcggcgc
     9661 cggtggcggt ggcctcggtg acggccttgt cgttggcggt cttcgcggcc cgccgctcct
     9721 ggcgcctgcg ctgcttcaca ctgcggtaga tcccggaggt ggcccggcgg acggtgatcg
     9781 cgtcggggtg gtcgaccggc agccggtcga gttccgccag cacgctcaga caggtcgcca
     9841 gccgctccgg gtcgatgccc ggcccctcgg ccgtcgcccg ctcggcccgg ccttcgtcag
     9901 tcaccgtcat cgccgctgcc gctttctggt tcgtctgttc ccctggacaa cggcgaaact
     9961 gtacggaagc gggggcgtat gcgccaaacc gtggcccgcg tcaccctcct ccgggcttgc
    10021 ggtacgcata gccgccggtc ggcgccgggg tggccgccgc ggccgggtgt ccggtgtccg
    10081 tcagcgcgcg gatcaccccg tggtcggggg agagcgcaca ggccgggtcg gtacgggcgg
    10141 cgtcgccggt cagggcgtac gcctgacagc ggcagccgcc gaagtcctcc gcgcggcggg
    10201 agcaggtgcg gcacggctcc cgcatccacc cctcgccccg gtagcggttg aaggcgcccg
    10261 agtggtccca gatccactcc agggagtggt cacggacatt gggcgggtcc aggtcaggca
    10321 ggctcgcggc ggcggggcag ggcagcgcgg tgccgtcggg cgcgacggtc agcgagaccg
    10381 cgccccagcc gcccatacag ggcttggcga ccccgtcgaa gtagtcgggc acgacccaca
    10441 ccaggtcggt ggccccgccc agccggtccc gccagcgctg gaccgtctcc cgcgcccgcg
    10501 cgagctggtc acgggtgggc agcagggcgt cccggttgcg tagcgcccag ccgtagaact
    10561 gggtgttggc cagctcgatc cggtcggcgc cccagtccac gccgcgccgg atgagggcgt
    10621 cgagcgcgtc gaggttgtcg cggtgcagga ccacattgag gccgagcggc agtccggccg
    10681 cgcgcaccag ggcggcggcc cgctccttgg cggcgaaggc gcggtgtccg gcgatccggt
    10741 cggcggcggc cgggtcggcg tgctgcacgg acagctggac gctgcgcagc ccggcggcgg
    10801 tcagcgcggt cagccgggcg ccgtccaggc ccactccgct ggtgacgagc tgggtgtaga
    10861 tcccggcgga ctcggcggcg gtgacgatct cggccagatc gccgcgcaac agcggctccc
    10921 cgccggagag atgggtgtgc accacgccga actccccggc ctggcgcatc acctccgtcc
    10981 actcggcggt ggacagctca cgggagcggc ggaccagctc cagcgggttg gagcagtagg
    11041 ggcagtgcag cgggcagccg tgggtgagct cggcgagcag ggcccagggg cggggcgcgg
    11101 cggtcatcgg acccagccct ccccgcgcat ccggccgagg aaggcacgca cgtcgtcggc
    11161 cacgggcgcg ccggggaagc ggctttcgag ctccgccacg atggtgtcga ggtcgcggtc
    11221 gccgtcgcac agccgcagga tccgcgcggc gctgccgcgc agcaccacca cccgctcggg
    11281 cagcaccagc agatcggcgt cgcgcacccg gtcgtggcgc aggctcaccg cgggggccag
    11341 cgcgggccgc catccggccg gggcgggcgg ggtgccggcg gcggtcatgt cccctccccg
    11401 gggccgtcct tggtgtcggc gtggtccacc gcgtccagca gcgaccacag cacatcgcat
    11461 ttgaaggcga gcgccgccac cgcgcggtcc tcgtcctcgg gggtgcgtgc ccaggtcagg
    11521 acggcgtcga gggcctcggt gctgtcccgg cgcccctggt cgacccggtt gcggaagtag
    11581 gtcaggccct cgcgctcgat ccatgggtag taccgctcga aggcgtcgat acgggtgagc
    11641 atgatgccgg gcgcggacag ttcggtgagc gaggcggcga ccgcttccag gggcccgcgc
    11701 agccggcaga agttgacgta gccgtcgacc gcgagccgca ccccgggcac cacctcctcg
    11761 gccgacagca gccggtcccg gtgcagaccg gcggcctcgc cgagccgcag ccaccgctcg
    11821 ataccgccct cgccttcggt ggtgccgtcg tggtcctgga tgcgccgcag ccacatccgg
    11881 cgcagccgtg gggtgtcgaa tttggcggtg atcagggcgt ccttgacggg gatatggcgc
    11941 tggtagtgga agcggttgag gatccagcgg cgcagttcgg cgggggtgag ctcacccgcg
    12001 tgcatccgta cgttgaaggg gtggcggtcg tggtagcgct cctgcgcgac cgcgcgcagc
    12061 cgttcctcca gccgtgtgcg tggggtgctc acaggtcgat caccatcccg tcggcggcca
    12121 cctcgacacc gagcttgcgc agctccgtgt ggtgcggcgc ggccgggtcg ttgagggggt
    12181 tggtgttgtt gaggtgggtg tacagcgtgc gtccttcgag cgcggcgagc cgccgcgccg
    12241 tgccgtccgg tccgtcgatc ggcagatgtc ccatggcggt ggcggtgcgc gagccgaagc
    12301 cactgctgag gggctcgtcg tcggaccaga aggtgccgtc gacgatgacg tggtcggcgc
    12361 tctcggcggc gcgctggaac gtgtcggacc aggcggcgag cgcgggggcg tagaggaggg
    12421 agcggccggt ggtgcggtcg gtcagccgca gcgcgaccac ccagccgccg tcgtccgggg
    12481 cgtcgagtcc ggccgcgtag cgggggcgtt tggcggagac ggggacggcg ccgatgacga
    12541 ggggcgagtc ctcggcgagc ggccggtcct cggggccgag ggggcgccag tccagccggg
    12601 cgtagggggt gaggacctcg cccaggtgga gtccggtcag cagggcgtgc cgcacctggg
    12661 cggtggccac gatctcgatg ccgtccgcct cgcgcagccg ggcgatgccg agggtgtggt
    12721 cgagttccgc gtcggtgagg atcaccccgg ccagcggggt gcggcgcggt tcgggcccgg
    12781 ggtgcagttc ggggtggtcc tcgacctggt cgccgaggtc gggggtggcg ttgacgaggt
    12841 accagcggcc ttcggcggcc tggacggcga gcgaggcgtg gcggcggcgc cacccggggt
    12901 gggcgcgtgc cccggagcat ccggggcacg cgcagttcca ctggggtacg ccgccacccg
    12961 ccgcggtgcc gagcacgcgc acgcgcatgg cgggcgggct cagcgggcgt tcagcgagta
    13021 ggcggtgacc tccagcgcgg tctccacgac cacgtagtcg ggggtctgcc aggcggtctg
    13081 cccggcgtcg gtgcgggtgc ggtccgtcgc ctcgggcgcg gtgcgcgggg tggtgtcgtt
    13141 catggtttcg acctgccttc catctggtgg gaaatcggtc cacaggacgg aacggacggg
    13201 ccgtcagcga tctcggtcca tgagggctct ccttcttcga gctgtgaagg ccgagggagg
    13261 ggatgcgcat ggtgttccgt ctgttgcagg gtcaccagcc gtcgggacgt ggtcaagaag
    13321 cgtgcaccaa aaaggtcatc cgacctctga tggttcgaca gccctgaggg cgtgaaatcg
    13381 accacgtggc cgacttcttg gcccgtacca atgcttgacg ccccgagtga cacctcctac
    13441 cttccgcgat gcaccggccc cctgctgtcg aatctgttga cgcgttagta agccttcctt
    13501 accgttcccc gcatgtgaac ggggatcaga caggagaacg ggatgaagag gtaccggaac
    13561 accgccgccg cggcggccgc caccgcgctc gccgccggcc tgctgatcgg gacggccgga
    13621 acgggaaccg ccgctcccgg ccgggccgat tcggctccct cggacatcaa gaccgtctcg
    13681 tccggctgga ccgtcccctg ggggctgagc tggctgcccg acggctcggc cctgatcacc
    13741 gagcgggact cgtatctggt ctacaagctc acccagtcgg gcaccaggac agaggtgggc
    13801 acggtgccca atgtggtgac caccgacggt gagggcgggc tgctgggcat cgcggtctcc
    13861 ccgaactgga acagcgacca caccatctat ctgatgcaca ccgcctccga gggcaaccgg
    13921 atcgcccgga tgacctacga cggctcctcg ctcggcggct accagaccct cgtcaccggc
    13981 atcaagaaga acaagtacca caacggcgga cgcctcaagt tcggcccgga cggctatctc
    14041 tacgccacca ccggcgaggc gcagacaccc gatctctccc aggacaagaa ctcgctcaac
    14101 gggaagatcc tgcgcatgac cacggacggc aagcccgccc cgggcaatcc gttcggcaca
    14161 ctcgtctact cctacggcca ccgcaatccg cagggcatca cctgggaccc gcagggccgg
    14221 ctgtgggagg ccgagttcgg cgacagcaag tacgacgagc tcaacctcat cgaggcgggc
    14281 aagaactacg gctggccgat ctgcgagggc gagtgctcca ccgccgggat gaccggcccc
    14341 aagcgccagt ggccgaccgg cgacgcctcg cccagcgggg tcacctacgc cgacggcgcg
    14401 atgtacctgg cggcgctgcg cggtgagcgg ctgtggcgga tcccggtgga cgggacgaac
    14461 gcgggcaccc cgaaggcgta ctacaccagc tcctacgggc ggctgcgcac cgtggagacc
    14521 gtgccgggca agaacacgct gtggctgtcc acgacgaacg ccgacagcaa cggcggggag
    14581 ccggacggcg cggacaaggt gttccaggtc gagttgaagt agccccgtcg cggaggggtg
    14641 atgcgtacgg tcgcggtccg ccgggccgcg accgtacgcc cgtgtcagtg cgcgagccgc
    14701 tcgttcatca gcaggaaggc gcccagaccg tggaggtcgt tcgtattgcg cgcgcggccg
    14761 aggtagtagg ccagatcccc gacgttggtg ccctcgctga tgtcggtgat gttcgtcagc
    14821 ccgtcggagc cgaccgacac cttacgcagc acgccctcat agccccttcg caccgcctcg
    14881 gtgtagccgc cgccgctgat ccagccgtgc tccagggccg cgtgcagcat cagggtgtac
    14941 atgctggagg ccgaggtctc ggtccagttg ccgggctcgc tcgccttgtc gaccacctgg
    15001 aaccaacggc cggtggccgg gtcctggtag cgcgcgaagc ccttcgccag gtgccgtacg
    15061 ttgtcgatca gttcggcgcg gcgcggatgg tcggcgggga gcagctccag cacctcgaca
    15121 tgggtcatcg cggtccagcc gatggcccgg gcccagaagt gggcggaggt gccggtggtg
    15181 gggtcgggct tccacggggc gtcgccgtcg gcgtcatagc cgtggtagat cagcccgttg
    15241 gccgccttga ggtggcggaa gtacaccgag aggttcctgg tgacctcctc gtacgcgtac
    15301 tcctggtcgc cgtaggcgat gccgtagcgc agcaggaagg gctgggccat gaagaccccg
    15361 tcgccccaca gttcgttggt cctgccggtg gcgtgccaca tcccgccgtc ggcggtgcgc
    15421 ggataggtgg tgatccgggc ccggatctgg ccggcggcgg tccggtagcg ggggtcgccg
    15481 gtctcctggt ggaggatcag cagcagattg ccggcctgca tcgcgtcgag gttgtcgaag
    15541 gtccggctca tatggccgtc ggcgtcgacg aagttgtcca cccagcgctt gatgtacgcc
    15601 aggtacgacg gctcatcgac ccgctggtgg acgcggtagg tgccgagcag gaacagcccc
    15661 tggatgtagc cccagccgcc gagggacgcg gggtccgggc ggcgggcgat ggtggagtcc
    15721 accaccgccc gcgaccagtc ggcgggcgcc gcaccggcgc ccgccgtcgg gaggagaaga
    15781 ccaccggtga ggcccagtgt gctcgcgaac agcgttctgc gactgatcat tcagtcctcc
    15841 ttgggtgtca ggacgccttg gaggcgccat gtacacgtca agaatatccg cacacactcc
    15901 gtaccggaac aaaagcggag gaaaggcgag gatgagccgg gcccgtcaag gccgaatccc
    15961 gtcaaggtaa ggtaagcctg accttaccta ttggagttgc tcgtgggccc ccttcgtctg
    16021 ttccccctgc tctcggccgt cctcgccgcg accgtcctca ccggctgcgg atcctcggat
    16081 cccgcgtcgt catcggcgtc ttcggggtca tcggggtctt cggggtcttc ggggtcttcg
    16141 gcggtctcga aggctccggg gtcctccgcg gcggacggtg acttcccgcg caccgtcgcc
    16201 catgagcagg gcagtacgcc gctgaaggcc gcgccgaagc gcatcgccgc gatcagcacc
    16261 ggacagctcg acgatctgct caccctcggc gtcgtaccgg tggccaccac ccgtgccgac
    16321 tacgccggac tcgtccccgg ctatctgcgc acggccttcc ccgggcaggc cgaggcgctc
    16381 ggctcgatga cggacatcgg cacccgcacc tcccccaacc tggagaagct ggccgccgcc
    16441 aagcccgatc tgatcctggt caacagcacc cagggcgccc tctaccccag cctggcggcc
    16501 atcgccccga ccgtggtcac caagggccgc ggggtgaact ggaagaagga cctgctgacc
    16561 gtcgccgacg cggtgggcag gcgcgagcgg gcccgcaccc tgctcacccg cttcgagaag
    16621 gacgccgccg accagggcga gaagctgggc ggcgaacaca cggcgctgtc gatggtgcgc
    16681 ttcaaccccg accgggtccg gatgttcggg aagaagtcct tcaccggcac catcgccgac
    16741 gacatggggc tcggccgccc cgagtcccag cgcttcgacg acatctcaca ggacctcagc
    16801 ggtgagcgga tcccgcggat ggacggcgac tggatcttct actccgtcca gggccgcccc
    16861 gggaagaccg acgccgccac ctatctgtcc aatccgctgt ggaagaagct gggtgcggtc
    16921 cgcggcgggc atatcgccaa ggtcgacgac gacccctggt acctcaacgc cgggcccacc
    16981 gccgcccggg tcgtactgcg cgacatcacc gagcacctcg ggcgctgaca ccgggcgccc
    17041 cagacggtgg caccgggcga caccgggcgc ctccggcgcc gacggcgggc gtcccgggcg
    17101 ctgaccgcgg gcacctcagg tggccgaaac cgaacccctc cacggccggg ccgacctctc
    17161 gacgccccgg gcggccgtgt caacctccga ccggcataag ccaccgtcac accccgtatg
    17221 cgatcgggac aatgcgtcac cacaagtccg tcctcaggca atagtctcgg cgtacaagcc
    17281 gtggctgagg aggtacccat ggggaccggg gatcgcgagc aggcatacgc acgggcgcgg
    17341 caggaggccg agcggctcac cgcgaacgga atccagggca tcgcgctgac ctgggtggac
    17401 aacgcgggtc tgacccgggt gaagtccgtg cccaccgcgc ggctgcccca ggccgcgcgg
    17461 cgcggggtcg ggatgtcccc cgtcttcgac gtctatctcg tggacgactc catgaccacc
    17521 agccgccatg tcggcggccc cgacggggat ctgcggctcc tccccgacct ggagcggctc
    17581 accccactgg ccgcacagcc cggctgggcc tgggccccgg tcgaccggta cgaccaggaa
    17641 ggccgggcgc accccgtctg ccagcggctg ttcgcccggc ggatggccga gcgggcacgg
    17701 gagcgggggc tggccgtgcg catggggttc gagaccgaat gggtcgtcac cacgggcgac
    17761 ccggaccagg acccgccgca ctaccccacc accggccccg cctacggcat ggcgcgcctg
    17821 gtcgacctcg ccgactatct cgccgatctg ctcggcacgc tggacgcaca gcacaccgag
    17881 gtgcaccagc tccatccgga gtactccccc ggccagttcg aggtgtccct ggcgcccacc
    17941 gatccggtgg ccgccgccga cctcgccgtg ctggtgcggg agacgatccg ggcgtgctcc
    18001 gggcgcgccg ggctcaaccc gatgttcggc ccggtggtgg acccgggcgg ggtcggcaac
    18061 ggcgcccatc tccatctgag cctgtggcag ggggaccgca atctgtgccg ggacggcgac
    18121 ggaccgcacg ccatgaccgc gacggccgag gcgttcctcg ccggggtact gcgcgaactg
    18181 cccgccctgc tcgccatcgg cgccccctcc cccgcgagct acctccggct cgaaccctcc
    18241 cgctgggccg gggcgtacca gtgctggggt ctggagaacc gcgaggccgc ggtgcgtttc
    18301 atcaccggcg caccggacga cccgggggcc gccaacgccg agatcaagtc cttcgacccg
    18361 gcggccaacc cctatctggt ggcgggcgcg gtcatcgccg cgggcctcgg cgggctggac
    18421 gccgggctct ccctgccgcc gcccgtctcc ggggaccccg cggtcgaggg gcgcgagcgg
    18481 cggctgccca cttcgctgct gacggcgctc gagcacttcg aggactcgac ggtgctgcgc
    18541 gaggcgctgg gcgatccgct cttcgagtcc atcgccgcgg tgcgccgggc ggaggccgcc
    18601 ctgttcgaga agtcgtcccc gcgtgagatc gccatcgcga cccggaggcg gtactgaccg
    18661 atggaggccg ccgagcagac ggatccgacc gagccgccgc tgccgcccct ggtggaccac
    18721 cactgccatg gggtggtccg ctccgagctg ggctcggcgg cgttcgaggc gttcctgacc
    18781 gaatccgacg cgcccgccgc gctcggcacc accttcttcg acagccagct ggggttcgcg
    18841 gtgcgccgct ggtgtccgcc tctgctgggc ctcgaaccgc actgcccccc cgcctactac
    18901 ctcgcccggc ggcgcgaact gggcgcccgg gaggtggccc ggcggctgct gagcgccacc
    18961 gggatcagcg agttcctggt ggacaccggg ctgccgggca atctgaccac cccccaggag
    19021 ctggccctcg cggcgggcgg caccgcccat gagatcgtcc ggctggagca gttggccgag
    19081 cggatcgccg acacctcgct gaccgccgac gacttcctga ccggggtggc ggacgggatc
    19141 cgggaggcgg cccgtacggc ggccgggttc aaatcggtgg ccgcctaccg ctacggactg
    19201 gacttcgaac ccgatccgcc gggccccggc gccgtccaca ccgccgccga acgctggctc
    19261 gcccggcgcg gccagggcgg caccgccgcc gcccgggtca ccgaccccgt actgctgcgc
    19321 catctgctgt ggtcggcggc gtacaccggg ctgccgctcc agctgcacac cggcttcggc
    19381 gaccccgatc tgcggctgga ccgctgcgat ccgctcgccc tcaccgactt cgtccgggcc
    19441 gtgcgcccca cgggctgcac cctgatcctg ctgcacggct atccgtacca ccgcggcgcc
    19501 gcctatctgg ccgccgtctt cccgcatgtg tacgccgatg tgaggttggc cctgtcgcac
    19561 accggggcac gggccggggc cgtgctcgcg gagatgctgg agctggcccc gttcggcaag
    19621 gtgctcttct cgaccgacgc ctacggtctg cccgaactgt atgtggtggg ggcgcggctc
    19681 ttccgggagg cgctgaccgg gctgctgacc cactgggtgg cggagggcgc ctggtcgcgc
    19741 cgcgacgccc gccgggtggc ggcgctgctg ggcgcggaca acgcccgccg cgtctacggc
    19801 ctgggcaccc cgaccccccg ggcggggtag ccgcccgcgg ttcccaccgc accggaacgg
    19861 tccgccccgc ccgtggtccg gacggcgacg ggccgccgcc ccgcgcgggt acggggtcgg
    19921 agtgcgcgtc gccgcggcgg gttcatgccg gatgaggcgg ccgttgccgc ccgagcccgt
    19981 tggcacggcg gagtttccgg tcaggtggcc aggtccagcc attccccgac ggccagcaca
    20041 tgtgcgcgcc gtccggcgtg cgtgcggaac tccttctccg ggtcggcgac ctcgacatag
    20101 cccgcgatct tgtccggctg ctccggctcg tagtggatcg gcaccgcgta ccgggcgtcg
    20161 aggatctccg cggccgcggc ggcctgccgc gggtccaacg cggcgggcag cgggctcggc
    20221 ggctgaaggt gcggtgcgtc gaccaccgcg ccgttggcgg gcaggaacac cgcgtcgaac
    20281 gggctgaacc ggcgcgcgat gagccaccag tagccgtgga acatcgtgtc gccgccgtgg
    20341 aagacccgct gcccgtcggc ctgcaccacc cagttcagct gcgggtcgcc cagcccgtcg
    20401 acggagggca ccgcggtgac gcggaacggc ccgatttcgc gggtggacca ggcatccacg
    20461 acctcggcgg ccagccggtg cagggccagt tcgcgctcgg ccggcagcgt cgtcacgttg
    20521 tccacgtcgt caccgtggcc gggcgccggt cgcagcaccg gcgcccccgg cgtcagcgcg
    20581 tccgcgagcg cggacgcgtc ggtgtggtcc cggtgcaggt gggtgaccag tgcggcggtg
    20641 gccttcccgc tcggctccgc cagcccctca ccgggcttcc accccgtgaa cagcggtgag
    20701 aggtcccgta cgtagtcgac caccagtcgc ctgccgcccg cctcgatctc cactccggcc
    20761 cagcccagtc gtcgcacccg catctcgcac tccttcgttc cggtgattgc cacgcgaaac
    20821 ttagcgtacg cgcgttcgct aaacaatagc gaacgcacgt acgctatcct tgccgtatgt
    20881 caccacgacg ctcagcggcc gaagcgcagg ccaccagggg ccggatcctc ggccgcgccg
    20941 ccgagatcgc ctccgaagaa gggctggacg gcatcaccat cggccggctc gccgaggaac
    21001 tggagatgag caagtccggg gtgcacaagc acttcggcac caaggagacg ctccagatct
    21061 ccacgctgga caaggcgttc gtggacttct ggcaccgggt ggtcgagccc accctgaccg
    21121 agccgccggg cctgcggcgg ctgcgcgcgg tgtgcgccaa ctccgtgggc tacctggagg
    21181 cgccgctgct gcccggcggc tgcctgatga ccgcggcact caccgaatac gacggccgcc
    21241 cgggccgggt ccgcgacgcg gtggccgagg tgtggtcgcg ctggcgggaa cagctgcggg
    21301 cggatctgac cgccgcggtg gagaacggcg agctgcccgc cggattcgac atcgaccagg
    21361 cgctgttcga gatcatcgcc gccggtctgg cgctgaacgc ggccatgcag ctccagcacg
    21421 accgggccgc cgcgggccgg gcccgccgcg cgatcgaacg ggccctggcc cagccctgac
    21481 gcgacccgcc ccggtccggc agccgacggg ccgccgccgc gcgcgccgga gacggccgcc
    21541 gacgcggggc ggccgatacc ggacacgggg gacgtccggg ccgaggcgcc gcgcgcgtcg
    21601 gtggcggacc ggggtccatg cccggcgcgg agcgcgtccg cagtaccgtg cccggaacgt
    21661 actcgaccgt aaccggagga gatcacatgc ggatcggcgg cacgaccgtc ctgctcaccg
    21721 gggccaccgg cggcatcggg cggacactgg cccacgcgct cgcggccaag ggcgccaagc
    21781 tgctgctcac cgggcgccgc gaggaggtgc tgcgcccgct ggcggaccag ctcggcggcc
    21841 gggcgatcgt cgccgatctg gccgaacggt ccgatgtgga gcgcctcgtc gaggaggcgt
    21901 cggacgcccg gatcctcatc gccaacgccg cgctgccctc cagcggcccg gtcctggact
    21961 accggcccga ggagctggac cgcgccctcg acgtcaatct gcgcgccccg atgctgctgt
    22021 cccggctgat ggcgccgcac atggtggagt cggggtccgg tcatctggtg atgatcggct
    22081 cgctgtcggg cc
//
