LOCUS       NZ_LJIW01000001        12397 bp    DNA     linear   CON 11-JUN-2024
DEFINITION  Streptomyces malaysiensis strain F913 SMF9131, whole genome shotgun
            sequence.
ACCESSION   NZ_LJIW01000001
VERSION     NZ_LJIW01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces malaysiensis
  ORGANISM  Streptomyces malaysiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
REFERENCE   1  (bases 1 to 6203920)
  AUTHORS   Xu,Y., Wei,J., Xie,J., Li,T. and Zhou,Z.
  TITLE     Genome sequence, genome mining and natural product profiling of a
            biocontrol bacterium Streptomyces malaysiensis F913
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6203920)
  AUTHORS   Li,T. and Zhou,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) State Key Laboratory of Silkworm Genome
            Biology, Southwest University, Tian Sheng Road, Beibei, Chongqing,
            Chongqing 400715, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-FEB-2015
            Assembly Method                   :: SOAPdenovo v. 2.04
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891865.1-RS_2024_06_11
            Annotation Date                   :: 06/11/2024 05:20:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,419
            CDSs (total)                      :: 9,336
            Genes (coding)                    :: 9,091
            CDSs (with protein)               :: 9,091
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 59 of 245
            Pseudo Genes (incomplete)         :: 218 of 245
            Pseudo Genes (internal stop)      :: 14 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:22:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4661193
            Orig. end                         :: 4673590
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJIW01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12397
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="22"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..12397
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12397
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7397](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7397
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(288..995)
                     /locus_tag="SMF913_RS18585"
                     /old_locus_tag="SMF913_13651"
     CDS             complement(288..995)
                     /NRPS_PKS="Domain: PKS_KR (9-97). E-value: 1.2e-07. Score:
                     23.7. Matches aSDomain:
                     nrpspksdomains_SMF913_RS18585_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060942.1"
                     /locus_tag="SMF913_RS18585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13651"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_102934766.1"
                     /transl_table=11
                     /translation="MLDLGLEGRTVLVTGATGAIGRAAARAFAEQGARVALAFRHRREA
                     AEALADELSGSDRGRAFAVPYALDDAASPRWVVAAVEERWGGLDVLVATAGRRGARREP
                     HTRFEDVPEEHWRPLVTDGFAPAIRTVQWSLAGMRKRGWGRIALVAAPYAADGDPGGEF
                     HAVARAGLHGLVRGLVDEVGGDGVLINAVCPGPTPPDRPPTTPEDIARTLLFLCSAANG
                     TVTGEALTLAGRR"
     aSDomain        complement(705..968)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMF913_RS18585_PKS_KR.1"
                     /evalue="1.20E-07"
                     /label="SMF913_RS18585_PKS_KR.1"
                     /locus_tag="SMF913_RS18585"
                     /protein_end="97"
                     /protein_start="9"
                     /score="23.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVLVTGATGAIGRAAARAFAEQGARVALAFRHRREAAEALADELS
                     GSDRGRAFAVPYALDDAASPRWVVAAVEERWGGLDVLVATAGR"
     CDS_motif       complement(894..968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SMF913_RS18585_0001"
                     /evalue="8.50E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="SMF913_RS18585"
                     /protein_end="34"
                     /protein_start="9"
                     /score="28.0"
                     /tool="antismash"
                     /translation="TVLVTGATGAIGRAAARAFAEQGAR"
     gene            complement(1139..2089)
                     /locus_tag="SMF913_RS18590"
                     /old_locus_tag="SMF913_13652"
     CDS             complement(1139..2089)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060943.1"
                     /locus_tag="SMF913_RS18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13652"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_069863907.1"
                     /transl_table=11
                     /translation="MHTVVILALDQVIPFDLATPIEVFTRTRLPDGREPYRVRVCGPTP
                     TIDAGVFALQAPYGLEALAEADTIVVPGRSDPLLPVPAEVNDALRDAAGRGTRIASICS
                     GAFTLAATGLLDGHCATTHWLGGALLAELHPKIQVDPDVLYVDNGQFLTSAGAAAGLDL
                     CLHIIRRDHGSAVAADAARLSVMPLEREGGQAQFIVHDQPPVPRGSLFEPLLRWMEDNA
                     ARDLTLTEIATHAGMSTRTLNRRFREHTGTTPLQWLHRARIRQAQYLLEATTHPVERIA
                     TQVGFGSPTSFRDRFKRVVGTSPHSYRSAFRRNAG"
     gene            complement(2180..3412)
                     /locus_tag="SMF913_RS18595"
                     /old_locus_tag="SMF913_13653"
     CDS             complement(2180..3412)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060944.1"
                     /locus_tag="SMF913_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13653"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_234701199.1"
                     /transl_table=11
                     /translation="MREIDTDVCVVGGGPAGLVLALLMLRSGARVTVLECARAHQRVVR
                     GEILQPGAMELLDALDVLSGARARGAHEHHRFLVMEGERVLLEADYRLLPAPYDHLLSV
                     PRPHLLDELLARCRRSPGFRYLPGRRAGGLLRRDERIAGVIADGPPGRCAVRARVVVGA
                     DGRFSRVRRLAGIGAGRAEAFAQDVLWCALTASPEEPPVRDVRVFRTGGGPVLVYGSWP
                     NRIQIGWTLPHRRYGHLAALGLDHVKERLVRAVPRYATLIRDQIRTPADLGVLDVFSAR
                     AERWAADGLVLIGDAAHTHSPIGAQGINLAVQDAVVLHPLLTRALAEGDTSAERLAEFE
                     RRRGPDIAAVMRMQTLQSRAILSQGAFTTRVRPRLARALRRTPLYRKILQRMAYGNPSI
                     RIADAGVCGRT"
     misc_feature    complement(3690..3708)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.56"
                     /tool="antismash"
     misc_feature    3712..3726
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.62"
                     /tool="antismash"
     misc_feature    complement(3716..3733)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(3731..4555)
                     /locus_tag="SMF913_RS18600"
                     /old_locus_tag="SMF913_13654"
     CDS             complement(3731..4555)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060945.1"
                     /locus_tag="SMF913_RS18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13654"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_030836626.1"
                     /transl_table=11
                     /translation="MDIKVLGPLSVEACGQSIVPSAGKPRQILALLSVYANQMLPVPTL
                     MEEIWGTQMPRSALTTLQTYILQLRRRLAAAYGPQAPQASKDVLATRYGGYVLEAQPGA
                     VDIHEYDRLVAAGREALDAGDDVQASLLLREALAVWRGPALVDVKVGPVLEIELARLEE
                     SRLGVLERRIEADLRLGRHAELLTELTELTARHPLHEGLHAQCMAALYRAGRPWQALEV
                     YQGLRARLVEDLGLEPSPRLQKLQQAVLASDPALDLDLDGHWRRPVLDLFAA"
     misc_feature    complement(4674..4688)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            4739..4993
                     /locus_tag="SMF913_RS18605"
                     /old_locus_tag="SMF913_13655"
     CDS             4739..4993
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS18605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13655"
                     /product="hypothetical protein"
                     /protein_id="WP_102934767.1"
                     /transl_table=11
                     /translation="MTDTPVPNESTSPACLAYSAENTEVTGVAEITERVRFAARAGAVG
                     AAEAVHPPAEADDLVIEDLSEAVWAVPAAGICICTVGAE"
     gene            5001..7397
                     /locus_tag="SMF913_RS18610"
                     /old_locus_tag="SMF913_13656"
     CDS             5001..7397
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03604"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060947.1"
                     /locus_tag="SMF913_RS18610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13656"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_102934768.1"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 3.8e-12,
                     bitscore: 44.3, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 5.2e-18,
                     bitscore: 63.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 4.7e-15, bitscore:
                     53.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6.3e-82, bitscore: 274.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 4.9e-70, bitscore:
                     234.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGELGFTPHLRVEPVPGEAVYLVSEHGVTALHGQAIAALAPLLD
                     GSRDLAHILTEAAAPARAAGPAGAVPAGQAERVIARLRAAGLVSERKRASTPEAAYWEL
                     AGPTAVGGPTPAPAPRASRPAVAPLVLGSADPGEVVRALRAAGLRTAASRTVGGAAADR
                     GAVDGDPTVSGAATPRREICQIAPRQHGDTELTLVVCDDYLDPRLAAVDAAHRAAGLRW
                     LPVKPVGTQAWLGPFLGAPDDPCWVCLADRLWRGRQAEAYLQRRLGRPGPVPRPPASLP
                     ASRAAALQLAALEAAKWLAGHRHPGQRELRTLDSLTATVDRHPLARRPQCAGCGDPALV
                     AARIQAPLSLPSPRDPLIGTDADTSPRGIVDTSPRGIMERYGHLVDPVTGLVTEIRRDP
                     RGPAVLNCFHARHPSYAGAGPHSGLDAVRAGLRAAAHGKGRTAEQARASALCEALEHYS
                     GHFQGDEPRQRARYRDLRPDDAVHPDTVQLFDPRQFRDPALPARHRINDPFDEGAELDW
                     TPVWSLTAERHRLLPTALLYYGAPQPPGGRCCRADSNGAAAGGTLADAVVRGFLELVER
                     DAVALWWYNRTRQPAVALDAFDDPWLAEVRAAHRGVRREVWALDLTTDFGIPVVAALSR
                     RLDKPAEDITLGFGAHFDRHTALCHAFAELNQMLPAVVEARADGGGYGAAEPEALRWFR
                     TATLADHPYLTPDPAAPPPPISGPPEGDATAAVRELARGRGMELLVLDQTRPDVGLPVA
                     KVLMPGMRPHWARFAPGRLFDVPVALGRLSAPTPYADLNPIPFFL"
     aSDomain        5010..5264
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SMF913_RS18610_Cyanobactin_D_RRE.1"
                     /evalue="2.10E-14"
                     /identifier="RREFam007.1"
                     /label="SMF913_RS18610"
                     /locus_tag="SMF913_RS18610"
                     /protein_end="88"
                     /protein_start="3"
                     /score="44.3"
                     /tool="antismash"
                     /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGQAIAALAPLLDGSR
                     DLAHILTEAAAPARAAGPAGAVPAGQAERVIARLRAAGLV"
     aSDomain        5010..5309
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SMF913_RS18610_NHLP_CD_RRE.1"
                     /evalue="2.60E-17"
                     /identifier="RREFam015.1"
                     /label="SMF913_RS18610"
                     /locus_tag="SMF913_RS18610"
                     /protein_end="103"
                     /protein_start="3"
                     /score="53.6"
                     /tool="antismash"
                     /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGQAIAALAPLLDGSR
                     DLAHILTEAAAPARAAGPAGAVPAGQAERVIARLRAAGLVSERKRASTPEAAYWE"
     aSDomain        5010..5318
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SMF913_RS18610_Goadsporin_CD_RRE.1"
                     /evalue="2.90E-20"
                     /identifier="RREFam013.1"
                     /label="SMF913_RS18610"
                     /locus_tag="SMF913_RS18610"
                     /protein_end="106"
                     /protein_start="3"
                     /score="63.2"
                     /tool="antismash"
                     /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGQAIAALAPLLDGSR
                     DLAHILTEAAAPARAAGPAGAVPAGQAERVIARLRAAGLVSERKRASTPEAAYWELAG"
     misc_feature    5022..5036
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.88"
                     /tool="antismash"
     misc_feature    7414..7427
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.07"
                     /tool="antismash"
     gene            7536..8774
                     /locus_tag="SMF913_RS18615"
                     /old_locus_tag="SMF913_13657"
     CDS             7536..8774
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060948.1"
                     /locus_tag="SMF913_RS18615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13657"
                     /product="histidine kinase"
                     /protein_id="WP_231981439.1"
                     /transl_table=11
                     /translation="MPDGAGNHPPRHHDDLAPRLAVVITVIVLVGYFSVAVTYVVDGNR
                     SGGTIDAAMLALALLPMTVLLCLQMLHSFPGLAPRLSRARHWTLALQAVLTFAPFAIFK
                     HAWLGMPGFLAGSSLLVLVPALAWPAFAAILLCTDVLLFQVGFGWGQVAYTSVSTALTG
                     LVVFGLSRLSGLVAEVSRSRAELARLAVAQERLRFSRDVHDLLGYSLSTITLKCELVHR
                     LVPRQNSRAQQELSEILQTSRQALADVRAVASGYRKMSLSAEAATARSMLAAAGISATA
                     EIDCAPLPELVDTVLASVLREGLTNVLRHSKADHCAFEARRSGHRVWLTLVNDGVGRPS
                     TILRADSTDGGSGIGNLRVRVENLGGRLRAGVRSDGWFELRAELDVSVAAPRRSGRERG
                     SEEEYGPGPTVTA"
     misc_feature    7562..7582
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    8673..8675
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8907..9512)
                     /locus_tag="SMF913_RS18620"
                     /old_locus_tag="SMF913_13658"
     CDS             complement(8907..9512)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717663.1"
                     /locus_tag="SMF913_RS18620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13658"
                     /product="response regulator transcription factor"
                     /protein_id="WP_079257772.1"
                     /transl_table=11
                     /translation="MVRVLIAEDMHMLRKALVALLEFEPDIEVVAEFPDGADILPRARE
                     LRPDVAVLDIDLPGMDGLTAAAELSTAVPECRTMMLTSLGRPGNLRRALAAHVSGFLLK
                     DSSPEKLSDAIRAVAKGERVIDPQLALAALDDGPQPLTPRELEVLRFAAKGEDSGQIAA
                     KLFLSVGTVRNYLTSAVTKLDARNRVDAIRIAREAGWL"
     misc_feature    9548..9563
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.87"
                     /tool="antismash"
     misc_feature    9687..9696
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(9741..11009)
                     /locus_tag="SMF913_RS18625"
                     /old_locus_tag="SMF913_13659"
     CDS             complement(9741..11009)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060950.1"
                     /locus_tag="SMF913_RS18625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13659"
                     /product="M6 family metalloprotease domain-containing
                     protein"
                     /protein_id="WP_102934769.1"
                     /transl_table=11
                     /translation="MVRPQVPEGVHQRPRLRRTQALLTSLSALIATTVVAGPAVAAGPG
                     GPCDLERTDAHHSEGLDTWNSRYPRPVRRLDAAMVFLSFPDARPRVTPARLAADHIPAT
                     PDFFKRASYGKFALRVHPLRRWIAMPQRSTAYAIQRDWNAQRRAAYLRDAIASADPHLD
                     FGRYDLVYLVADPDAPGVDADATKVVNFEKPLRADGVDLRRLVTVFEHHPPDRNVLAHE
                     TGHVFDLPDLYHRPKDTDGNAEWDTYVGDWDLMGSQFGMAPDPFGWHKWKLGWLGARQV
                     ACDRLTGPRRYTLQPLSAPMARGGPGADLRTRLVVVRTGPTTALAIEARGGRGNDAGTC
                     TEGVLVYRVHNDKASGDGPVQVLDGHPTTSACWNESVYPELADAPLGVGDTLSVKEDDV
                     RITVAGRAADGGWTVRVNRQAPG"
     misc_feature    complement(11434..11447)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    12098..12112
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 gcgccctgac caccgccatg ggcagggcgc agatctgcac cggcaccagg ccggcgcggg
       61 cgacggccgc cgcgcatgcg gacggcaccg cgacccgcac ctggtgcccg gcctcgagca
      121 gggcgcgcgc cagcggcacc atggggacga gatgggcgcc cgaggcccag gtcgtgaaca
      181 ggacgcgcac ggtgacctcc cgcggagtcg agccggccgg accgccccgt ccggccgatg
      241 gacatgacac cgagccgact catcgcatcc cgcgctcctc ggcgggctca gcggcgcccc
      301 gcgagcgtca gcgcttcgcc ggtgaccgtg ccgttggccg cggagcacag gaagaggagg
      361 gtgcgggcga tgtcctcggg ggtggtgggc ggccggtcgg gcggggtggg cccggggcat
      421 acggcgttga tcagcactcc gtccccgccc acctcgtcca ccagaccgcg gaccagaccg
      481 tgcagcccgg cccgcgccac cgcgtggaac tccccgccgg gatcgccgtc cgccgcgtac
      541 ggcgcggcca ccagcgcgat ccggccccag ccgcgcttgc gcatcccggc gagggaccac
      601 tggacggtgc ggatcgcggg cgcgaagccg tcggtgacca gcggccgcca gtgctcctcc
      661 ggcacgtcct cgaaccgggt gtgcggctcg cgtcgcgcgc cccttcgccc ggcggtcgcc
      721 accagcacgt ccagcccgcc ccagcgctcc tccacggcgg ccacgaccca gcgcggcgac
      781 gcggcgtcgt ccagggcgta cggcacggcg aaggccctgc cccggtcgga tccggacagc
      841 tcgtcggcca gcgcctcggc ggcctcgcgg cggtgccgga aggcgagcgc gacccgggcg
      901 ccctgctccg cgaaggcgcg cgcggcggcc cggccgatgg ccccggtggc cccggtgacc
      961 aggaccgtgc gcccctccag gccgaggtcc aacatgggca ctcctcgcgg tcgttcccac
     1021 tgagaaggcc atggtcgccg ccgtgactcg aggcagcctc gactcgcgcc cgcccctgcc
     1081 ggaatgtggc ggccgtccgg cgttcgccga acggcttccg gcgtttcgca gaagcggctt
     1141 atccggcgtt tcgccggaag gcggagcggt agctgtgcgg gctggtgccg acgacacgct
     1201 tgaagcggtc ccggaaggag gtgggcgagc cgaagccgac ctgggtggcg atgcgctcga
     1261 ccgggtgggt ggtggcctcc agcagatact gcgcctggcg gatcctggcg cggtgcagcc
     1321 actggagcgg ggtggtcccg gtgtgctccc ggaagcggcg gttaagggtg cgggtgctca
     1381 tgccggcatg ggtggcgatc tcggtgaggg tgaggtcccg cgcggcgttg tcctccatcc
     1441 accgcagcag gggttcgaac agcgatccgc gcggtacggg cggctggtca tggacgatga
     1501 actgggcctg cccgccctcc cgttccaggg gcatcacgga cagccgggcg gcgtcggcgg
     1561 ccacggcgga accatggtcg cgccggatga tgtgcagaca cagatcgagc ccggccgcgg
     1621 cgcccgccga ggtgaggaac tggccgttgt ccacatagag cacatccggg tcgacctgga
     1681 tcttcggatg gagctcggcg agcagcgcgc cgccgagcca gtgtgtggtg gcgcagtgcc
     1741 cgtcgagcag cccggtggcg gcgagggtga aggccccgga gcagatcgag gcgatacggg
     1801 tgccccgccc ggccgcgtcc cggagcgcgt cgttcacctc ggcggggacc gggagcaggg
     1861 ggtcgctacg gccgggcacg acgatggtgt cggcctcggc gagcgcctcg agcccgtacg
     1921 gcgcctggag ggcgaacacc ccggcgtcga tggtgggggt gggcccgcag acccggaccc
     1981 ggtagggctc gcggccatcg gggagccggg tgcgagtgaa cacctcgatc ggggtggcca
     2041 gatcaaaggg gatcacctga tccagcgcca ggatcacgac agtgtgcatg gcctcaacct
     2101 aggccgtacg gcctatggca ccaccgccgg ggtggcgaga agccggtcca ccaacgaatt
     2161 ccggccaccg cgcttcgggt catgtccggc cgcacactcc ggcgtcggcg atacggatcg
     2221 acggattgcc gtaggccatg cgctggagga tcttgcgata gagcggtgta cgacgcagcg
     2281 cccgcgcgag acgggggcgc acccgggtgg tgaacgcgcc ctgcgagagg atcgcccggc
     2341 tctgcaaggt ctgcatccgc atgaccgccg cgatatcggg cccgcgccgc cgctcgaact
     2401 ccgccagccg ctcggcgctg gtgtcgccct cggccagggc acgggtcagc agggggtgca
     2461 gcaccaccgc gtcctgcacc gcgaggttga tgccctgggc gccgatcggg ctgtgggtgt
     2521 gggccgcgtc gccgatcagc accagaccgt cggcggccca gcgctcggca cgggcggaga
     2581 agacatcgag cacaccgaga tcggccgggg tccggatctg gtcgcggatc agcgtggcgt
     2641 accgcggcac ggcgcgcacc agccgctcct tgacatggtc gaggccgagg gcggccagat
     2701 ggccgtagcg ccggtgcggc agggtccagc cgatctggat ccggttcggc caggagccgt
     2761 agaccagcac cgggccgccg ccggtgcgga acacccgcac atcgcggacc ggcggctcct
     2821 ccggtgacgc ggtgagcgcg caccacagga catcctgggc gaacgcctcg gcgcggcccg
     2881 ccccgatgcc cgccagccgc cggacccgcg agaaccggcc gtccgcgccg accacgaccc
     2941 gcgcccgtac ggcacaacgg cccggggggc cgtcggcgat caccccggcg atccgctcgt
     3001 cccgccgcag cagaccaccg gcccgccgtc cgggcagata gcggaagccg ggcgagcggc
     3061 ggcagcgggc gaggagctca tccagcagat gggggcgcgg aacgctcaac aggtggtcgt
     3121 acggggccgg aagcagcctg tagtcggcct ccagcagcac ccgctcgccc tccatcacca
     3181 ggaaccggtg gtgctcatgg gcgccgcggg cgcgggcgcc ggagagcaca tcgagcgcgt
     3241 ccagcaactc catcgcgccg ggctggagga tttcgccgcg gaccacgcgc tgatgcgcgc
     3301 gggcgcactc caggacggtc acccgggccc ccgaccgcag catcagcagc gccagcacca
     3361 gaccggccgg gccgcccccg accacgcaca catcggtgtc gatctcgcgc atcatcgcgc
     3421 ctcctgctgg tcgggctcca gggcctgggc accgggcgcc agtgacaccc ccgacgctcc
     3481 ctggacgcgc tacggctccg cttgcccgcg cggggggatc gggcagcgga gccgtagcag
     3541 gcccggctga agggcggcgc cgggcgtttt tggggggatg gttcatcgga cggggacggc
     3601 tggtacgaga cctacgggaa ccggacccac gagacttcgg acgagggcgg tatcagggat
     3661 cgactgtcgg ctgtcggctg tagctgtcgg ctgtcggtct attcggtcga gggactatgc
     3721 ggtcgagggg ctatgcggcg aacaggtcga gcacagggcg gcgccagtgg ccgtccaggt
     3781 ccagatcgag cgccgggtcg gaggcgagca ccgcctgctg gagcttctgg agccgcggcg
     3841 acggctccag cccgaggtcc tcgaccagcc tggcgcgcag cccctggtag acctccagcg
     3901 cctgccaggg gcggcccgcg cggtagagcg cggccatgca ctgggcgtgc aacccctcat
     3961 gcagcggatg gcgggccgtc aactcggtga gctcagtgag cagctcggca tggcggccaa
     4021 gccgcagatc ggcctcgata cggcgctcca ggacgccgag ccggctctcc tccagacggg
     4081 ccagctcgat ctccagaacc ggcccgacct tcacatccac cagcgcgggg ccgcgccaca
     4141 cggccagcgc ctcgcgcagc agcagggacg cctgcacatc gtccccggcg tccagcgcct
     4201 cccgccccgc ggccaccaac cggtcgtact catggatgtc caccgcaccc ggctgggcct
     4261 ccagcacata tccgccgtag cgcgtcgcca gcacatcctt ggatgcctgc ggggcctgcg
     4321 ggccataggc ggcggccagc ctgcggcgca gctggaggat gtaggtctgc aaagtggtga
     4381 gcgcgctgcg tggcatctgt gtgccccaga tttcctccat aagagtgggc accgggagca
     4441 tctggttggc gtagacggaa agcaatgcaa ggatctggcg cggcttgccc gcgctcggca
     4501 cgatcgactg accgcacgcc tcgacgctca gcggccccaa caccttgatg tccatggtcg
     4561 tgtacctccg tcaacggtcc gtcaagtgcc tcctggccgc gcggccctgc caccgaggca
     4621 tctaagagcc tcgcttgtgg gcggcctgtg cggccagtgc cggagtaacg agctcgatat
     4681 gagttccaga gccccgcacc atgacaaatt cacacccctg gcgatgagag agtccgcgat
     4741 gaccgatacg cccgtcccaa atgagtccac gagccccgcc tgcctggctt attccgccga
     4801 gaacaccgag gtcaccgggg tcgccgagat caccgaacgc gtccggttcg ccgcgcgcgc
     4861 cggggccgtc ggggccgccg aggccgttca tccgcccgcc gaggcggacg acctggtcat
     4921 cgaggacctc tccgaggccg tctgggccgt ccccgcggcc ggcatctgca tctgcaccgt
     4981 cggcgccgaa tgaccggccg atgaccggcg aactgggctt cacaccacat ctgcgggtcg
     5041 agccggtgcc gggcgaggcc gtgtatctcg tctccgagca cggggtcacg gcgctgcacg
     5101 ggcaggcgat cgccgcgctg gcgccgctgc tcgacgggtc tcgggacctc gcccacatcc
     5161 tcaccgaggc cgccgcgccc gcccgcgccg cgggcccggc cggcgcggtc ccggccgggc
     5221 aggccgagcg cgtcatcgcc cgcctccgcg cggccgggct ggtctccgag cggaagcgcg
     5281 cctcgacccc cgaggcggcg tactgggagc tggcggggcc gaccgccgtg ggcggcccca
     5341 ccccggcgcc cgcgccccgg gcgtcccgcc ccgccgtggc cccgctggtc ctcggctcgg
     5401 ccgatccggg cgaagtggtc cgggcgctgc gcgccgcggg gctgaggacc gctgcatcga
     5461 ggaccgtggg cggggccgcg gcggaccggg gggcggtgga cggcgatccg acggtttccg
     5521 gggctgctac tcctcgccga gagatatgtc aaatcgcccc tcgtcaacat ggcgacacgg
     5581 aactcaccct tgtggtgtgc gatgactacc tcgatccccg gctcgccgcc gtggacgccg
     5641 cgcaccgcgc cgccggcctt cgctggctgc ccgtcaaacc ggtgggcacc caggcgtggc
     5701 tgggcccgtt cctcggcgcc cccgacgatc cgtgctgggt ctgtctggcc gaccggctgt
     5761 ggcgcggacg gcaggccgag gcgtatctcc agcgccggct cggccgcccg gggccggtgc
     5821 cgcgcccgcc cgcctccctg cccgcgagcc gcgccgcggc gctccaactc gccgccctgg
     5881 aggccgccaa gtggcttgcc gggcaccggc atccgggcca gcgggagctg cgcaccctgg
     5941 acagcctcac cgccaccgtg gaccgccatc cgctcgcccg tcggccacag tgcgccggct
     6001 gcggcgatcc ggcgctggtc gcggcccgga tacaggcgcc cctgtcgctg ccgtcgccgc
     6061 gggacccgct catcggcacc gacgccgaca cctcaccgcg cgggatcgtc gacacctccc
     6121 cgcgcgggat catggagcgc tacggacatc tggtggaccc cgtcaccggg ctggtcaccg
     6181 agatccggcg cgatccgcgc ggcccggccg tcctcaactg cttccacgcc cgccacccct
     6241 cgtacgccgg ggcgggcccc cacagcggtc tggacgccgt aagggcgggg ctgcgggccg
     6301 ccgcccacgg taagggccgc acggccgaac aggcgcgggc gagcgcgctg tgcgaggccc
     6361 tggagcacta cagcggccat ttccaggggg acgagccccg tcagcgcgcc cgctatcgcg
     6421 atctgcgccc ggacgacgcg gtgcatccgg acaccgtcca gctcttcgat ccgcggcagt
     6481 tccgggaccc cgccctcccc gcgcgccacc ggatcaacga tccgttcgac gagggcgcgg
     6541 agctggactg gaccccggtg tggtcgctca ccgccgaacg ccaccggctg ctgcccaccg
     6601 cgctgctgta ctacggcgcc ccgcagcccc cgggcggccg ctgctgccgg gcggactcca
     6661 acggcgcggc ggccggcggc actttggccg acgccgtcgt acggggcttt ctggagctgg
     6721 tggagcggga cgcggtcgcc ctgtggtggt acaaccgcac ccggcagccc gccgtggccc
     6781 tcgacgcctt cgacgacccc tggctggccg aggtgcgcgc cgcccaccgg ggcgtgcggc
     6841 gcgaggtgtg ggccctggac ctcaccacgg acttcggcat tccggtggtc gccgcgctct
     6901 cccggcgcct cgacaagccc gccgaggaca tcaccctcgg cttcggcgcc cacttcgacc
     6961 ggcacaccgc gctctgccac gccttcgccg agctcaacca gatgcttccg gcggtggtcg
     7021 aggcccgtgc cgacggcggg ggctacggcg cggccgagcc cgaggcgctg cgctggttcc
     7081 gcaccgcgac cctcgccgac cacccgtatc tgacacccga tccggccgcc ccgccgcccc
     7141 cgatatccgg ccccccggag ggcgacgcga cggccgccgt aagggagttg gcgcgcgggc
     7201 gcgggatgga gctgctggtg ctggaccaga cccggccgga tgtgggactg ccggtggcca
     7261 aggtgctgat gcccgggatg cgcccgcact gggcccggtt cgcgcccggc cggctcttcg
     7321 acgtacccgt cgcgctcggc cggctgtcgg cccccacgcc ctatgcggac ctcaacccga
     7381 ttccgttttt cctgtgattc cccgtgacac ccggtaactc tgcgtacacc atgagccttc
     7441 tacgcggcct ctccacctcc accgaagatc ggatactctc gggcaagcca cccaatccgg
     7501 ctcgaccatc cggaggacga gtgcagggga gcctcttgcc cgacggtgcc gggaaccacc
     7561 caccgcgtca ccatgacgat ctggcgccgc gtctggccgt ggtcatcacg gtcatcgtgc
     7621 tggtgggcta cttctccgtg gccgtcacct atgtggtcga cggcaatcgt tcgggcggga
     7681 cgatcgacgc ggcgatgctc gcgctggcgc tgctgccgat gaccgtcctg ctctgcctcc
     7741 aaatgctgca ctccttcccc ggcctcgcgc cccggctcag ccgcgcccgg cactggacgc
     7801 tggcgctcca ggcggtgctg accttcgccc cgttcgcgat cttcaagcac gcctggctgg
     7861 gcatgccggg cttcctggcc ggctcctcgc tgctggtgct ggttccggcg ctggcatggc
     7921 ccgcgttcgc ggccatcctg ctgtgcacgg acgtgctgct gttccaggtc ggcttcggct
     7981 ggggccaggt cgcgtacacc tcggtctcca ccgcgctgac cgggctggtg gtcttcgggc
     8041 tctcgcggct gtccgggctg gtcgccgagg tgtcccggtc ccgggcggaa ctggcccggc
     8101 tggcggtcgc ccaggagcgg ctgcggttct cccgggatgt gcacgatctg ctgggctaca
     8161 gcctgtccac gatcaccctc aaatgcgagc tggtgcaccg gctggtgccc cggcagaact
     8221 cccgcgccca gcaggagctc tcggagatcc tccagacctc ccgtcaggcc ctcgccgacg
     8281 tacgggccgt ggccagcggc tatcgcaaga tgtcgctgtc ggcggaggcg gccacggccc
     8341 gctcgatgct ggccgcggcg ggcatcagcg ccacggccga gatcgactgc gcaccgctgc
     8401 cggagctggt ggacacggtg ctggcgagcg tgttgcgcga ggggctgacc aatgtgctgc
     8461 gccacagcaa ggccgaccac tgcgcgttcg aggcacggcg cagcggccac cgggtgtggc
     8521 tgaccctcgt caacgacggg gtcggccggc cgtccacgat cctgcgcgcc gacagcacgg
     8581 acggcggcag cggaatcggc aacctccggg tgcgggtgga gaacctcggc gggcggctgc
     8641 gcgcgggcgt acggtcggac ggctggttcg agttacgggc ggagttggat gtgtccgtgg
     8701 ccgcgccacg gcggagcggc cgggagcgcg gctcggagga ggagtacggc ccggggccga
     8761 ccgtgacggc gtgacagggg gcccgtggcg gcgtcacaag gcccgtggcg gcgtggcccg
     8821 cgacgcgcgg cgagaacccg gtgcggcacg gcgagaaccg gggcggcgcg gcgagacagt
     8881 ggccccgcgg caaggcccgg tcaccgctac agccagcccg cctctcgggc gatccggatg
     8941 gcgtcgaccc ggttgcgggc gtccagcttg gtcacggcgg acgtcaggta gttgcgcacc
     9001 gtgcccaccg acagaaacag cttggccgcg atctgcccgg agtcctcccc cttcgcggcg
     9061 aaccgcagaa cctccagctc acgtggggtc agcggctgcg gaccgtcgtc cagggcggcc
     9121 agcgcgagct gtggatcgat cacccgctcg cccttggcga cagcgcggat ggcgtcgctc
     9181 agcttctccg gactgctgtc cttcagcaga aagccggaga catgggcggc cagcgcccgg
     9241 cgcagatttc cggggcggcc gaggctggtg agcatcatgg tgcggcattc ggggacggcg
     9301 gtgctcaact cggccgcggc ggtgagcccg tccataccgg gcagatcgat gtccagcacc
     9361 gcgacatccg ggcggagctc acgggcgcgc ggcaggatgt cggccccatc ggggaattcg
     9421 gccaccacct cgatgtccgg ttcgaattcc agcagggcga ccagggcctt gcgcaacata
     9481 tgcatgtctt ccgcgatcag caccctgacc atgccgcccc ctgctccacc cgcccggctt
     9541 ccccccgcat gacgattatt cccccgctct cccggacctt ccatcgattc gcgggcaaat
     9601 ccgcccgtcg aacgcatatc ccgtagcacg agcgcgatcg cgcgccccct tgtcatgccg
     9661 caccaccccg gcaggcagcg gtgcgggaag gcggccaggt cccggccggg acgggggcct
     9721 tcggccgacg ggccgccgcg tcatccgggc gcctggcggt tgacccgtac ggtccagcct
     9781 ccgtcggcgg cgcggccggc caccgtgatc cgtacgtcgt cctccttgac cgacagggtg
     9841 tcgccgacgc cgagcggggc gtcggcgagt tcgggataga ccgactcgtt ccagcaggcg
     9901 gaggtggtgg ggtggccgtc cagcacctgg acggggccgt cgccggacgc cttgtcgttg
     9961 tggacgcggt agaccagcac gccctcggta caggtgcccg cgtcgttgcc gcggccgccg
    10021 cgcgcctcga tggccagcgc ggtggtgggc ccggtgcgga ccacgaccag ccgggtgcgg
    10081 aggtcggcgc cgggcccgcc gcgcgccatg ggggcgctga ggggctggag ggtgtatctg
    10141 cgcggaccgg tgaggcggtc gcaggccacc tggcgcgcgc cgagccagcc cagcttccac
    10201 ttgtgccagc cgaacggatc gggtgccatc ccgaactggc ttcccatcag atcccagtcg
    10261 ccgacgtagg tgtcccattc ggcgttaccg tcggtgtcct tcggccggtg gtagaggtcg
    10321 ggaaggtcga agacatgccc ggtctcatgg gccagcacat tgcggtccgg cggatggtgc
    10381 tcgaaaacgg tgaccagacg acgcagatcg acaccatcgg cgcgcagtgg cttttcgaag
    10441 ttgaccactt tcgtcgcatc ggcgtccaca ccgggggcat cggggtcggc gaccagatag
    10501 acgaggtcgt agcggccgaa gtcgaggtgc ggatcggcgg acgcgatggc gtcgcgcaga
    10561 taggcggccc gccgctgggc gttccagtcg cgctgtatgg cgtacgcggt ggaccgctgg
    10621 ggcatggcga tccagcgccg cagcggatgt acgcgcagcg cgaatttccc gtaggaggcc
    10681 cttttgaaga agtcgggggt cgcggggata tggtcggcgg ccagccgggc gggggtcacc
    10741 ctgggcctgg cgtcgggaaa ggacaggaag accatcgccg cgtcaagtcg gcgtaccggg
    10801 cgcggatagc gggagttcca ggtgtccagg ccctcggagt ggtgggcatc ggtgcgttcc
    10861 aggtcacagg gtccgccggg gccggcggcg acggcggggc ccgccaccac ggtggtcgcg
    10921 atgagcgcgc tcagcgaggt cagcagggcc tgggtccgac gcagccgagg ccgctggtgc
    10981 actccctcgg gtacctgagg acgcaccatg tcgacctccc gggcgtagtc ggaacaccca
    11041 ctccaccctg aggtgaattg gcggggtacg ccctgttgag ttgggctggt cgagtgaaga
    11101 ggccgctatc cgggtacgta acagacggtc acattcggtc agagcggctg tttgcacgcg
    11161 cagagtcgaa cagatacgac caaacacatt gtcaaggcgg cggtgagcgc gatgacgtcg
    11221 atggaacgcc cgaagtacga gcccctatga tcggcacatc ttcagcgggg aatccccctt
    11281 caggcaggca attacggtct gcccggcacc cggtgtgaga catgcgcaag atgtgtacga
    11341 acaacttgga aacaacaaac gccacgcggg agcgagcggt gagcggaacc cccgacgggc
    11401 agggccgcgc cccgggcgcg acgctgcccg cgatcacaga gcgtgatgcc atcccgagcg
    11461 tcctccctgt cgcggaggac cccggcgcac cacgtccggc cccaagcgcg ccgtcggtcc
    11521 cgggcgcgcc cccgagcccg gtcacgcccc cgggcgccgg gcacaccccg ggcccggcgc
    11581 ccggcgacta ccgcgccgcc ttcaacgcgg cgcgcctggc catggcggtc gtcgaccgcg
    11641 aggggagggt gctcgacgcc aaccccgcgc tcggcgccct gctcggcacc gatccgggcc
    11701 tgctgaccac ccgcagcgcg gccgacctgg ccgatctgca cgaggatccg cgcacctggc
    11761 gggagtaccg ggaggtcctg ggcggccgcc tcgcgcggct gcgccgcacc cggcggctgc
    11821 tgcgcgccga cggccatgcc ctgtgggccg agatcaccgt cgagccggcg ccggacagtt
    11881 gcagtctgct gctgtccatg gccgacatca gcgatcagcg ggatctccag gggcggctgc
    11941 gccatctcca gatgcacgac ccggtgacca ggctgcccaa ccgcagcctg ttcttcgagc
    12001 ggatgacctc ggcgctggag gcggccacct acgaccacga gggcaccggc cggatcgggc
    12061 tctgctatct cgacctggac ggcttcaagg cggtcaacga caccctcggc caccgggtcg
    12121 gcgaccggct gctcggcgcg gtcgcccagc ggctcatcga ctgcgcggcg cccggcggcc
    12181 atctggtggc gcggctcggc ggggacgagt tcgccctgct ggtccgcaac tccaccggca
    12241 ccgagcagct gtgcgacctc gcccggtcgg tgctggccgc ccttcaggag ccgttcgacg
    12301 tgggcgggca gcggctgtcg gtgtcggcga gcatcggcgt ggtggagcgg cccgcggccg
    12361 gcacccacac cacctggctg atgcaggccg cggacac
//
