LOCUS       NZ_LJIW01000001        26463 bp    DNA     linear   CON 11-JUN-2024
DEFINITION  Streptomyces malaysiensis strain F913 SMF9131, whole genome shotgun
            sequence.
ACCESSION   NZ_LJIW01000001
VERSION     NZ_LJIW01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces malaysiensis
  ORGANISM  Streptomyces malaysiensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
REFERENCE   1  (bases 1 to 6203920)
  AUTHORS   Xu,Y., Wei,J., Xie,J., Li,T. and Zhou,Z.
  TITLE     Genome sequence, genome mining and natural product profiling of a
            biocontrol bacterium Streptomyces malaysiensis F913
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6203920)
  AUTHORS   Li,T. and Zhou,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2015) State Key Laboratory of Silkworm Genome
            Biology, Southwest University, Tian Sheng Road, Beibei, Chongqing,
            Chongqing 400715, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-FEB-2015
            Assembly Method                   :: SOAPdenovo v. 2.04
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891865.1-RS_2024_06_11
            Annotation Date                   :: 06/11/2024 05:20:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,419
            CDSs (total)                      :: 9,336
            Genes (coding)                    :: 9,091
            CDSs (with protein)               :: 9,091
            Genes (RNA)                       :: 83
            rRNAs                             :: 5, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 245
            CDSs (without protein)            :: 245
            Pseudo Genes (ambiguous residues) :: 0 of 245
            Pseudo Genes (frameshifted)       :: 59 of 245
            Pseudo Genes (incomplete)         :: 218 of 245
            Pseudo Genes (internal stop)      :: 14 of 245
            Pseudo Genes (multiple problems)  :: 43 of 245
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:22:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3976214
            Orig. end                         :: 4002677
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJIW01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26463
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="20"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26463
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26463
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16463](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16463)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(248..260)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    250..260
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(274..1230)
                     /locus_tag="SMF913_RS16185"
                     /old_locus_tag="SMF913_13181"
     CDS             complement(274..1230)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13181"
                     /product="phage tail domain-containing protein"
                     /protein_id="WP_102934544.1"
                     /transl_table=11
                     /translation="MTAALNKTGRPELAPWQYEIGGVVLGTGSYVPVGNVEGLGAPAPR
                     SQDADNSNSDGTTPGRDFYGPRPLRFEAGIKTPGDPVKAAEILARLERALDTPDARTNP
                     DGRHVLRGRWPGHSTRRMYGRLRRLEASSTANAVHGWIPLDLEFVGLDNPRWYDDEVSK
                     LTLGLDQAARGHGGDRTVDEAMGRAAACRRPADPRHRPAHDRPGWVTNHGDVPTYPSLR
                     VQGPVTAPRIWNTVTSRVLELDVSLREGEWVELETRPGTCWALRNGTVNVANDLGPASR
                     LDLFTLPPGRSEIAWTAADPSGTARLEVAWRSAYTTL"
     gene            complement(1230..5486)
                     /locus_tag="SMF913_RS16190"
                     /old_locus_tag="SMF913_13182"
     CDS             complement(1230..5486)
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /locus_tag="SMF913_RS16190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13182"
                     /product="phage tail tape measure protein"
                     /protein_id="WP_102934545.1"
                     /transl_table=11
                     /translation="MAGFTLTVAMRAEVRDLIAGFRTASGQARTFADRTDAANRSLARL
                     DANGARLASQFAALNRSTRAAVGELNRITARASAARASLRAAGDDGARSMSRLQRAVSG
                     AGRRGISATNLLSGGSLLLGAGAMVEEGNRYQRQMNLFRAVTSATAVQMKRAAVVAQEL
                     GNDLTLPGSTAADAAEGMVELSKAGFRADQSIDAVRASLQLAAAADVNAATSARYLGDI
                     MDQFGLGADQASRASDTLAATANNASGSITDIYYSMRYAGPVANALGVSLQDTAAAVGM
                     LGKAGILGQTAGTSLRGIFANLAAPTPQMKNGLKDLGIQAWDAQGNFRGLRVVIDGLSK
                     AEHELSQKDFAAGVTRAFGKPALSGAAALAHQGTESFDALSVAVRQTGAAATITASRGQ
                     GLTGAMTQLRTQARQTGLALYEGMAPGLEWVTRLLTRGMAGATPYLTTALEYGRNLAVL
                     YGPELKAKAGSGLGGLIEEAQGLLGPLKELGAHTLATGLNLLINAAQTLGDVLRHAADG
                     VEPILHAISTLGEDGGAAVGTLDIIATVANVAMDAVSGLSAVLVPIGHLVGGLVNAFGA
                     LPAPVQAAALAMLLFRRAQPALTNLATTVSGPVRSSFQSFAQQMRVQQSLAAANGVTLS
                     RYGAAWAALQARIGFLGNMTSAFRSANGAGTTFTGTLNGVTRAAGSGLRSALGGITNAL
                     GGPFGVVMAGVSVGLGLLTSRQQRAAQAAAEHQQRISSLTAALRESGGQINGDVRGQAA
                     QILLDTKTSQGQLTKVMEQAGVPLATLTDAYLGQGTSLDALQKRLQTTANAHREYKDVA
                     GGKASVLDYTGVGRQYKDAADALGSVKGEMATSIKNARELAKATKGAGDGTSAYDRLKS
                     AVGGLADETADADTRTRSLKSALDLLSGGQISLQAAKAKVNSATLDLKEGGKKLNRDQG
                     YGGKELVNEDRTLNTTTRNGQQLYTQLTALSDAAADASVATYDLAKRNGDALPEALAKA
                     RGEMSRARAEAIKAARSYGLTKTQAAGVADSLGLLPSKVSLLLQTKGMDSTLANLIAVQ
                     AEFHRLPNAKTIKVDSLSDGAQKKLRSLGFTVKTVPGTRQIRITAPTAAARKNLDGLID
                     KLGRTPKSKNVHVSAPTAAAIKSLSAVQAKIRTTPGAKSVIVRAPTARARKELQALGFR
                     IEKVPGSKNVRVIVPTGGPRKAADSIQRRINALRGKSVTVTTRHVNVLETIRKAPSDTA
                     DALRRQAENLTNHARGGVVDYYADGGITGGPRRENHVAQIAPAGSYRIWAERETGGEAY
                     VPMAAAKRERSKAIVETVVDRFGGQVEWYANGGVRGARGRDYTPMLASSFKQARSVAAM
                     AGVVRAFDLRTGSDRARTRVVDARAGGRVQVVVVREQQPLIGSMPVTVTNSAATPEQIG
                     SEMMRTLRNAQRGGRV"
     gene            complement(5520..5720)
                     /locus_tag="SMF913_RS16195"
                     /old_locus_tag="SMF913_13183"
     CDS             complement(5520..5720)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13183"
                     /product="hypothetical protein"
                     /protein_id="WP_093701274.1"
                     /transl_table=11
                     /translation="MCPECHTRLEEWDAKRGGDPHAYVTDTLRCPGCELIEQERDHVPG
                     DRSGYGVKIQLLPRGLHRDNT"
     gene            complement(5861..6343)
                     /locus_tag="SMF913_RS16200"
                     /old_locus_tag="SMF913_13184"
     CDS             complement(5861..6343)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13184"
                     /product="hypothetical protein"
                     /protein_id="WP_146055569.1"
                     /transl_table=11
                     /translation="MDRLRRRPRAQNTLRICDDDQLRQRFEEAEQSAQRARFLAEANPD
                     DEAASRRAADAATALEEAGTALDSASDFLTFLALPRPALEELISQHPPTEQQAQEGAVF
                     NPDTFPAALVSAASLDGMSRKEAEELLNTWSAPDANALWDAGWQVQQESRVELGKG"
     gene            complement(6421..7059)
                     /locus_tag="SMF913_RS16205"
                     /old_locus_tag="SMF913_13185"
     CDS             complement(6421..7059)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13185"
                     /product="hypothetical protein"
                     /protein_id="WP_102934547.1"
                     /transl_table=11
                     /translation="MSLKKPSTQTRFLRRGISKIYWLKKVNDPKRPTRREISEPNRFDL
                     TQAVSDIEGWALENDPIETPDMGSTFNSSIPGNDKAENSSLTFYEDRFSDAIEQQLPKG
                     AKGYVVLLRKGDIPGSRSVDVFPVQVATRAATYSTGNEAAKFKVDFTITEEPSLDAPVP
                     EGDYHTLLKPDENCDDDHERGQGDGDHVDVTVVSSTAATATVHEHGDED"
     misc_feature    complement(7050..7069)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.95"
                     /tool="antismash"
     gene            complement(7181..7627)
                     /locus_tag="SMF913_RS16210"
                     /old_locus_tag="SMF913_13186"
     CDS             complement(7181..7627)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13186"
                     /product="hypothetical protein"
                     /protein_id="WP_102934548.1"
                     /transl_table=11
                     /translation="MIARLPVTRALAALVEHATGRPCGIGELPRVQRRTGWEVASIPYT
                     ILDSLPAEFTGPPLWDWHADAAWSYQITSVGERVDQVEWLADRVRVGVVGRSDGCWSHD
                     LRIPEGRAIDRELTYEAGGEPSVSASGAIVSYVQRFTITVTPAA"
     gene            complement(7624..8052)
                     /locus_tag="SMF913_RS16215"
                     /old_locus_tag="SMF913_13187"
     CDS             complement(7624..8052)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016754.4"
                     /locus_tag="SMF913_RS16215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13187"
                     /product="HK97 gp10 family phage protein"
                     /protein_id="WP_102934549.1"
                     /transl_table=11
                     /translation="MAPANPHPNAHPDAVAFRDPIALAAALARMGPAARARTRTITRHH
                     AMLLRVRIQRNASGRPGPNVITGQYRASWDVRMRTGGGEVTAEVFSDTPQARRLEYGFV
                     GVDSIGRHYRQPPFPHIEPAFRQTEPAFIQALADGVLP"
     gene            complement(8052..8483)
                     /locus_tag="SMF913_RS16220"
                     /old_locus_tag="SMF913_13188"
     CDS             complement(8052..8483)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039652.3"
                     /locus_tag="SMF913_RS16220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13188"
                     /product="DUF6093 family protein"
                     /protein_id="WP_146055570.1"
                     /transl_table=11
                     /translation="MVFDVDGARRVLARILDDKLEVWRDSAGRTDDVLDETTGRLVPPV
                     PDEELVWDGLGAVMPLGRPAITKPVGGSVAVEPPTTDYQAVLPVDAPVLRRDDVVRVAG
                     SVRRGGPRDPQLVGRRFRFSDGAVGTYSVVRIVRVQVID"
     gene            complement(8473..8844)
                     /locus_tag="SMF913_RS16225"
                     /old_locus_tag="SMF913_13189"
     CDS             complement(8473..8844)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13189"
                     /product="hypothetical protein"
                     /protein_id="WP_146055571.1"
                     /transl_table=11
                     /translation="MDDSNETTHRVRITARGPKAKIEIDGQRIDPGALTSYTLSHHTGE
                     PPHLILDSEHLDSLAFDGLARVAIADVPAPGPAAAIFLDAIDPEALERAALARPDLGTE
                     PHSLTKAMLTQLGEWARGL"
     gene            complement(8881..9921)
                     /locus_tag="SMF913_RS16230"
                     /old_locus_tag="SMF913_13190"
     CDS             complement(8881..9921)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325336.1"
                     /locus_tag="SMF913_RS16230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13190"
                     /product="hypothetical protein"
                     /protein_id="WP_250850588.1"
                     /transl_table=11
                     /translation="MREISDLARSAEHEGKLSLAAAAQNKAALIASDCGMPDLARTLCW
                     RHAEVYLCAQPLSAQEARYALEPVVNIARLLIRDGDANGAYRLLDALVQAARTRGRAEV
                     DGHTICFKDLTTTDEEHQQLHQWLWTILLGDGTRALVAAGAWNRARSQARRHRGVGHRL
                     LDGRQVEVLLRCLAGDPDGAYAFLGESVPTEPWEHSVASCLAALCRHLSGINDETIMTA
                     MVRNYLNLDTTAELDLFRTRLGLTALDLTETDPALATAVTTRLLPEAASCRNGYVAREV
                     LAHPSCRERLKPPAERILYAAVYSAGLDQGHMPTPLERELLQAAESGATTTEHLLAHKR
                     PATGST"
     misc_feature    complement(8956..8958)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9403..9405)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12085)
                     /gene="fxlM"
                     /locus_tag="SMF913_RS16235"
                     /old_locus_tag="SMF913_13191"
     CDS             complement(10001..12085)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325335.1"
                     /locus_tag="SMF913_RS16235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13191"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_102934553.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-31, bitscore:
                     108.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 8.1e-46, bitscore: 154.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDDEWPQRVIEFTDWPDAERVAVAHLRPILDSGGTRQWSFIRKA
                     PTWRLRYRPDPADPTYLDQALDTLVADGAVREWVPGIYEPETAAFGGPDGMELAHEFFH
                     RDSRHALDQLACQQQNPGSPVLGRRELAIVLFSACLRAAGLDWYEQGDVWARVEAERQH
                     PDRALLQRHRVAVRRLMTVDVGPHSSPVADGRLAYLTDWLTTFEWAGQQLAHLNRRGRL
                     ERGLRAVLAHHLIFHWNRLGLPREDQSALSTLAKEVVMGTNDTAASTPSTGEAATTVTG
                     VNSDTIETSPDDLRAHLVDQLVQDGSIRTARVEQAMRAVPRHLFVPQAPLEKAYSNTTV
                     DTKYDSAGRSISCASQPGIVALMLEQLHVEPGMKVLELGAGTGFNAGLLGHLVGEQGHV
                     TTLDVDHDIVEGARIGLKAAGLGNVTVILGDGAQGYAANAPYDRIVATVGAHAVPLAWL
                     DQLAPGGRLLSPLRLRGSVSRSIAFERDAERRWRSVGSEMNTFMPLRRGIADDPRIFVP
                     LTEDGSVTLVTNGDQTVDTDALADVLNQPRAEAWTGVTFRGPESPEWLELWLTCALPNG
                     LSRMPAKREAIDSGLLTNPYASSTATFDKGTLTYLTRRKADHTAEDGATLYEFGVIGHG
                     PDADHLTERVTEAVRTWDSDFRTRNVAFEIRPLDAPSPEQKPGRFTFDNPLNRIVIEWQ
                     "
     misc_feature    complement(11579..11581)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12106..13374)
                     /locus_tag="SMF913_RS16240"
                     /old_locus_tag="SMF913_13192"
     CDS             complement(12106..13374)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491155.1"
                     /locus_tag="SMF913_RS16240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13192"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_102934554.1"
                     /sec_met_domain="LANC_like (E-value: 6.4e-48, bitscore:
                     161.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITPQNDHDVQTAVDLIADRLASPGQARTWNLTHGWWPQSLANGA
                     VGVALLHIERARIGLASWQRAHDWLACAAAGGAVGGPDSHPFYGVPALTFALHAAATGW
                     PDRYARALETLDKHLAATVQARLAAAHARIDRGEPPALAEFDAIRGLSGMAALLMCREV
                     HTDLARQVIAYLVRLTEPIKDGEELLPGWWSALSPSGAPSTDFPRGHGNNGMAHGIAGP
                     LAALSLATFHGITAPGQSKAIERICSWLDRWQQQGLAGPWWPYWITREQLRTGDPGIGP
                     SRPSWCYGAAGIARAQQLAALALGDTARQHMAEDTLLRAVTDPGQLDQTTDASLCHGFA
                     GLVHLTQLAAADAINPGLAQALPHLLQRLVPAGPQVLADSLLAPPQGAAAIGLLEGAAG
                     IAMALHSMQEGTSAVWNACLLIN"
     gene            complement(13371..16463)
                     /locus_tag="SMF913_RS16245"
                     /old_locus_tag="SMF913_13193"
     CDS             complement(13371..16463)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325333.1"
                     /locus_tag="SMF913_RS16245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13193"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_102934555.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.4e-199,
                     bitscore: 661.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.7e-16,
                     bitscore: 58.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.8e-22, bitscore:
                     77.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKSCLPYRCAGTAMVRASGHRLPLASWPDLADSSPHRVARWRG
                     WLQAAWDREELAAAVEQASPALARQVHAVCVGEVEDARRVRRAASALVRYALRMHGRAT
                     PFGLFAGVVPMAFADEPLVVWGDQHRAFVRADGTWLADVIKRLEACPAVLHRLSLVVNN
                     CAFLRGGRLVVPYPPRSGRAEEPAAEVSLRYTAAVRLVVEAARAPLRGRELVEKVSAEF
                     HQVALSKVESLVTSLVSQGVLLSALHAPAGTFDAFDHLMQQIAGAGVEDVPDVAQLTAR
                     LQKVQSKLAAHNVPTGPVEGRRLRAALRTDMLAVSTVVEQPVAVDARLDCTLVLPHQVA
                     RAAEEAVSLLARLSPLPYGSPAWKSYHNRFFERYGIGSLVPVRDLVDADLGLGFPDGYL
                     DAEPEAGTAVSGRDRRLFALAQQAALEGRDEVHLDEELVGALTPGEPDRVRLPPHLELR
                     FRLQAPDIAAVAQGEFTLAVVSPSRGIGTTTGRFIGLLDPEEQAQARKAFIHLPTSDSG
                     ARPVQLSFTPLNRCDTHVTRAPDVLPDVISLAEHRVDGGAGLIALDDLAVGCDPQRLYL
                     ASLSRQQRLEPMAPHALDLRAHTPPLARFLLEIAKATSTVVTPFTWGAANALPFLPRVR
                     YGRTILSPARWRLHRSDVPDRCAAWPQWREALEQWRHRSRVPDWVALTEGDRALPLNLT
                     EAAHLELVRSHLATSESAVLTETQPGADGWLDGHAHEITVPLQADHPALSRATPPVSTA
                     RLVTREHGHVPGASRWLMAKIYSHTKRHPEILGHHLPGLFARWEQPPMWWYTRYRDPRW
                     HLRLRLALADVGDFATGAARVAEWATELRRQGLVGDVQFATSYPETGRWGTAGGLEAAE
                     TVFAADSAVLVTAFAQPTRPHPQALAAANLVATATAFTGSTVVGMDWLIRHGHLTDPGP
                     LDRAVRAEALSLADPTGDWAGLRAAPGGTAIHATWAARARVLTAYGDRLRACDDGTDPD
                     AVLDSLLHAHHIRAAGIDKADERTCIRLARAAALAWKARSA"
     aSDomain        complement(15714..15989)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SMF913_RS16245_Lanthipeptide_LanB_RRE
                     .1"
                     /evalue="9.50E-19"
                     /identifier="RREFam001.1"
                     /label="SMF913_RS16245"
                     /locus_tag="SMF913_RS16245"
                     /protein_end="250"
                     /protein_start="158"
                     /score="58.9"
                     /tool="antismash"
                     /translation="LVVNNCAFLRGGRLVVPYPPRSGRAEEPAAEVSLRYTAAVRLVVE
                     AARAPLRGRELVEKVSAEFHQVALSKVESLVTSLVSQGVLLSALHAP"
     misc_feature    complement(15993..15995)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16557..16685)
                     /locus_tag="SMF913_RS16250"
                     /old_locus_tag="SMF913_13194"
     CDS             complement(16557..16685)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491158.1"
                     /locus_tag="SMF913_RS16250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13194"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_232564462.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.9e-17, bitscore:
                     61.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDEFELDITVLESGDRSAKLINLTDDGCGSTCSSPCASSVA"
     misc_feature    16669..16684
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    16935..16953
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.09"
                     /tool="antismash"
     gene            complement(16944..17549)
                     /locus_tag="SMF913_RS16255"
                     /old_locus_tag="SMF913_13195"
     CDS             complement(16944..17549)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.4"
                     /locus_tag="SMF913_RS16255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13195"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_107504273.1"
                     /transl_table=11
                     /translation="MDAHSHQAVAFSFLGRLGTAVWPRLTASHPVHIQQVFDAAWTEGL
                     SLPLGEAKAASQTVALIDGMDFHRQSDKDAVAHAYQERQRTRVYESLNVRSDGWFSTVT
                     LRLTAIMRHQVICTAYESHAGDRNLGAHDDEWLGVITQMRGAKRWLVWPETTGAPEEIV
                     TRVGDVLILPQGVKHEVSTPDSPGYSVHLVFAITDELV"
     misc_feature    17531..17546
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.09"
                     /tool="antismash"
     misc_feature    17531..17549
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.91"
                     /tool="antismash"
     gene            complement(17562..17918)
                     /locus_tag="SMF913_RS16260"
                     /old_locus_tag="SMF913_13196"
     CDS             complement(17562..17918)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13196"
                     /product="hypothetical protein"
                     /protein_id="WP_093701261.1"
                     /transl_table=11
                     /translation="MTVLASEPQVEQHANLMQQLHDVLKQHEIGGAFRLMFVPSELEIS
                     DDEVLVQAVNAERGVVEIHPCKLSELTPGEVLHATQVIDPSDEPLIARGPGPFGKDCKA
                     SLRLNGSRGHLYAT"
     gene            complement(18045..18875)
                     /locus_tag="SMF913_RS16265"
                     /old_locus_tag="SMF913_13197"
     CDS             complement(18045..18875)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF020897.4"
                     /locus_tag="SMF913_RS16265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13197"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_180990635.1"
                     /transl_table=11
                     /translation="MLRALEWLACQGEMMTITDPDMVQSQVGVLNKVSAILAVLEEGPA
                     HLETVISETGLKRPTVRRLVLAMQELGLVEADQQEQFIVGPRLIRLARAAHQAIVHREL
                     RQQLSALRATTGVRSVRLERRCDDQRICMAEDPRLNSAATDRKPARVAAMGDDPVSRVF
                     LAWQELSQGREVWRDAAAECSAIRCRGWVQGVADGGLVLAVAVRGRDGELAAVLSLSSR
                     FQRTRREASYGHEVITVAIEAAARISHHLRANETTGLVEGLEDRAQRVGPRSVE"
     gene            complement(18917..>19045)
                     /locus_tag="SMF913_RS50155"
                     /pseudo=""
     CDS             complement(18917..>19045)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018567695.1"
                     /locus_tag="SMF913_RS50155"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SIRDISEVTGRSFGFIYTMLNEAGVELRPRGGSYSRDEALEI"
     gene            complement(19615..19836)
                     /locus_tag="SMF913_RS16275"
                     /old_locus_tag="SMF913_13198"
     CDS             complement(19615..19836)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13198"
                     /product="hypothetical protein"
                     /protein_id="WP_079257516.1"
                     /transl_table=11
                     /translation="MAVLVEHAAAWGVAGVVHAPETLRPVPGEHGEPFTLVAYDDPRLP
                     WTLACREVVALHGCTAVDLGDLTEHTAA"
     misc_feature    complement(21488..21503)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            21623..22780
                     /locus_tag="SMF913_RS16280"
                     /old_locus_tag="SMF913_13199"
     CDS             21623..22780
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SMF913_RS16280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SMF913_13199"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_146055572.1"
                     /transl_table=11
                     /translation="MAPQKRSRSETGTLTAGQGPPARTASGIVCGHLLKIIRERIPLTQ
                     SRLAEELGIDTTTVQGWETGRRSLAAISSAQFLRLKRHLLGRGAEPTLLPLLDLAVEAD
                     SVIEYSLNDTLNSDDITQHPLHSWVFTRASTHMIAWALTGEQPTILPKAPASTPRRRGP
                     TPGSPLLPTPQRDKLFANLRRTAEIADRVGEDGSLLRRQALYLCAYDTSVDTHSWLADM
                     RERRQPPLRHASWTPAWSDARSVATSLTRYGDSETLQTFIERGMGGDASEMANLNYWAH
                     WLGLDPVPRASDAFMSDVDGRSWEALPLLRNLADRLDPSLGAVDLNIHSVWALISSKPG
                     VLSADRELHRDLTSRVDRLLDSDVISRQSRRELENVHYGLRLSSR"
     gene            22804..23379
                     /locus_tag="SMF913_RS16285"
                     /old_locus_tag="SMF913_13200"
     CDS             22804..23379
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137148.1"
                     /locus_tag="SMF913_RS16285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13200"
                     /product="HD domain-containing protein"
                     /protein_id="WP_079260442.1"
                     /transl_table=11
                     /translation="MTDDQADKGTVGYLFEMGALKRGKRSGWWIAGVKDPETIAEHSFR
                     TAIIGAVLAMMEGADPAKVALLCTFHDTQETRVGDIPWIGRRYLEAASNERVTADQVSK
                     TPPAVAEGIKAVVHEYENGDSLEVLVAHDADKLECMLQGMEYLEQGYRNAQEWVDTTRA
                     KLKTPSALALAEAAQGMSSMEWKHTYLG"
     gene            complement(23490..23819)
                     /locus_tag="SMF913_RS16290"
                     /old_locus_tag="SMF913_13201"
     CDS             complement(23490..23819)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063615.1"
                     /locus_tag="SMF913_RS16290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13201"
                     /product="hypothetical protein"
                     /protein_id="WP_102934560.1"
                     /transl_table=11
                     /translation="MDEFQRSWLLAQLGPDTDSADLERRYFRLRSVRAVALEVLGERRA
                     KLLGDPLKVTVDGVVTMDLQENLRGIERQIDAICQTSAPDDPEDGDGEGNTLATSFMVP
                     SRRYR"
     gene            complement(24077..25084)
                     /locus_tag="SMF913_RS16295"
                     /old_locus_tag="SMF913_13202"
     CDS             complement(24077..25084)
                     /NRPS_PKS="Domain: PKS_ER (23-247). E-value: 2e-19. Score:
                     61.8. Matches aSDomain:
                     nrpspksdomains_SMF913_RS16295_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982144.1"
                     /locus_tag="SMF913_RS16295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SMF913_13202"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_102934561.1"
                     /sec_met_domain="ADH_N (E-value: 2e-05, bitscore: 22.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.6e-11, bitscore:
                     42.5, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRVVHTRGGSPADVLTVIEEPDPATPEHGQVLIRASVFTVHPG
                     DLQTIEAYPGNAAQPVPAGTEVTGVVEAIGPGTRVAPGVEVGGRVTVFPQPGAWAQWIV
                     ADADLVAAVPEELSDEVAAQMLANPLTAVMLRREAQEHLAFGYDGCLVQTAAGSSVGRL
                     VTGVSQFHNFPLVNVVRSDRGAAELRKRFPDVPVVSTEHPGWADEVRKAAGGRPVSVAL
                     DPIGGKLAESLLDLLSPGGKLVSYGLIAKEPISVHASTLLSKSLTMRGKNVGQWPSEAS
                     TERRQSDVATAKQIALELRDQFDVAATYGLAELADAVEHAVRPGKVGLVLVRPW"
     aSDomain        complement(24344..25015)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SMF913_RS16295_PKS_ER.1"
                     /evalue="2.00E-19"
                     /label="SMF913_RS16295_PKS_ER.1"
                     /locus_tag="SMF913_RS16295"
                     /protein_end="247"
                     /protein_start="23"
                     /score="61.8"
                     /tool="antismash"
                     /translation="DPATPEHGQVLIRASVFTVHPGDLQTIEAYPGNAAQPVPAGTEVT
                     GVVEAIGPGTRVAPGVEVGGRVTVFPQPGAWAQWIVADADLVAAVPEELSDEVAAQMLA
                     NPLTAVMLRREAQEHLAFGYDGCLVQTAAGSSVGRLVTGVSQFHNFPLVNVVRSDRGAA
                     ELRKRFPDVPVVSTEHPGWADEVRKAAGGRPVSVALDPIGGKLAESLLDLLSPGGKLVS
                     YG"
     misc_feature    25257..25272
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    complement(25321..25336)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
ORIGIN
        1 gggccggtcg gctcgaccgc caccacggca tcaccgatgt tgctctgcgt gtaggccccc
       61 tgccacggtc gggcgccgtg gatgagcgcc gagccgtcac cgacacggac gccggggccg
      121 ggggtctcca gtgggcggac cttcaggtcc tcgctctccg caacaccctg tcggccccgg
      181 gcgaggtcgc ggatcatcag gcgcagcgcg cgggcggagt ggtcggcccc gcgcaccatc
      241 atggggggtt gcaacgtcac gagtgctctc cgttcacaga gtggtgtacg cggaccgcca
      301 cgccacctcg aggcgcgcgg tgccggacgg gtcggccgcg gtccacgcga tctcggaccg
      361 tccgggcgga agggtgaaca ggtcgagacg gctggcgggc ccaagatcgt tggcgacatt
      421 gaccgtgccg ttgcgcaggg cccagcaggt gccgggccgg gtctccagct ccacccactc
      481 gccctcgcgc aacgaaacgt cgagttcgag gactcggctg gtgacggtgt tccagatccg
      541 cggggcggtg accggtccct gcacgcggag gctcgggtac gtcggcacgt cgccgtggtt
      601 ggtgacccag ccgggccggt cgtgggctgg gcgatggcga ggatcggccg ggcggcggca
      661 cgcggcggca cggcccatcg cctcatcgac agtgcggtcc ccgccgtggc cgcgagccgc
      721 ttggtcgagg ccgagggtca gcttcgacac ctcgtcgtcg taccagcggg ggttgtccag
      781 gcccacgaac tccaagtcga gcggtatcca cccgtggacc gcgttggccg tgctgctggc
      841 ctccaggcgg cgaagtcgcc cgtacatacg gcgtgttgag tggccgggcc accggccacg
      901 caggacgtgg cggccgtccg ggttggtgcg cgcgtccggg gtgtccaggg cccgttccag
      961 ccgcgcgagg atctcggcgg ctttcaccgg gtcgccgggc gtcttgatgc ccgcttcgaa
     1021 ccgcaggggg cgcggtccgt agaagtcccg tcctggggtg gtgccgtcac tgttggagtt
     1081 gtcggcgtcc tgcgacctgg gcgcgggggc gccgagccct tcgacgttgc cgaccgggac
     1141 gtagctcccg gtgccaagca cgacaccgcc gatctcgtac tgccatgggg ccagttcggg
     1201 gcggccggtc ttgttcagtg ctgcggtcat cacactctcc cgccccgctg cgcgttgcgc
     1261 agcgtgcgca tcatttcgga gccgatctgc tcaggggtgg cggcgctgtt ggtgacggtg
     1321 accggcatcg agccgatcag cggctgctgc tcccgcacga cgacgacctg gactcggcca
     1381 ccggcgcggg cgtcgaccac gcgggtgcgg gcacggtcgc ttccggtgcg gaggtcgaag
     1441 gcgcgcacga cgcccgccat cgccgcgacg ctgcgggcct gcttgaagga gctggcgagc
     1501 atcggggtgt agtcgcggcc gcgggctccc cggacgccac cgttggcgta ccactcgacc
     1561 tggccgccga accggtcgac cacggtctcg acgatggcct tgctccgctc tcgcttggcg
     1621 gcggccatag gcacgtatgc ctccccaccg gtctcccgct ccgcccatat gcggtagctc
     1681 ccggccggtg cgatctgggc gacgtgattc tcgcggcgcg gtccgccggt gatgccgccg
     1741 tccgcgtagt agtcgacgac accgccccga gcgtggttgg tcaggttctc ggcctgtcgg
     1801 cgtagagcgt cggccgtgtc ggacggtgct ttgcggattg tctccaggac gttcacgtgc
     1861 cgagtggtga cggtcaccga cttgccgcgc agcgcattga tcctgcgctg gatcgagtcg
     1921 gccgccttac gaggtccgcc ggtcggcacg atgaccctga cgttcttgga gccggggacc
     1981 ttctcgatcc ggaagccgag cgcctgcaac tccttccgag cgcgagccgt aggagcgcgc
     2041 acgatgaccg acttcgctcc gggggtggtc ctgatcttgg cctggaccgc cgacaagctc
     2101 ttgatggccg ccgcggtcgg cgcggagacg tggacgttct tgctcttcgg ggttcgaccc
     2161 agcttgtcga tcagcccgtc caggtttttc cgtgccgccg ccgttggcgc cgtgatcctg
     2221 atctggcggg tgccgggcac cgtcttgacc gtgaagccga ggctgcgcag cttcttctgc
     2281 gcgccgtcgc tcaaggagtc gaccttgatg gtcttggcgt tggggagccg atggaattcg
     2341 gcttggaccg cgatcaggtt cgcgagagtg ctgtccatgc ccttcgtctg gagcagcaac
     2401 gacaccttcg acggcagtag gccaaggctg tcggcgacgc cggcagcctg agtcttggtg
     2461 aggccgtagc tccgcgcggc cttgatcgcc tccgcacgag cgcggctcat ctccccacgg
     2521 gccttggcga gtgcctctgg aagggcgtcg ccgtttcgct tggccaggtc gtacgtcgcc
     2581 acggacgcgt cggccgccgc gtccgacagg gcggtgagct gggtgtagag ctgttgtccg
     2641 ttcctcgtgg tggtgttgag cgtccggtcc tcgttgacga gttcctttcc gccatagcct
     2701 tggtcacggt tgagtttctt gcccccctcc ttcaggtcga gggtggctga gttcaccttc
     2761 gccttcgcgg cctggagaga gatctggccg cccgacaaca ggtcgagggc gcttttgagg
     2821 gagcgggtac gggtgtcggc gtcggccgtc tcgtcggcca aaccccccac ggcgctcttg
     2881 agccggtcgt aggcggaagt accgtccccg gcgcccttgg tcgccttcgc cagctcgcgg
     2941 gcattcttga ttgaggtggc catctcgccc ttgacacttc cgagggcgtc ggctgcgtcc
     3001 ttgtactgcc gtccgactcc ggtgtagtcg aggacgctgg ccttgccgcc cgccacgtcc
     3061 ttgtactcac ggtgggcgtt cgcggtggtc tgaagcctct tctgcaaggc gtcgagcgag
     3121 gtgccctgcc cgaggtaggc gtcagtcagt gtcgcgagtg gaacaccggc ctgctccatg
     3181 accttggtga gctgcccctg gctcgtcttg gtgtccagca ggatctgggc agcctgacca
     3241 cgcacatcac cgttgatctg cccaccggac tcacgcaggg ccgccgtgag cgaggagata
     3301 cgttgctgat gctcggcagc agcctgcgcg gcgcgctgct gacgggaggt gagcaagccg
     3361 aggcccacgg acacacccgc catgacgacg ccgaagggtc caccgagtgc gttggtgatg
     3421 ccgcccaacg ccgagcgcag gccggacccg gccgcgcggg tcacgccgtt gagggtgccg
     3481 gtgaacgtag tgcccgcgcc gttcgcgctc ctgaacgcgg acgtcatgtt cccgaggaac
     3541 ccaatgcggg cctgaagagc ggcccaggcc gcgccgtatc gggacagcgt gacaccgttc
     3601 gccgctgcga ggctctgctg tactcgcatc tgctgggcga aggactggaa gctggagcgc
     3661 accggcccgc tgacggtggt cgccaggttg gtgagggccg gctgggcgcg gcggaacagc
     3721 agcattgcca gagccgccgc ttggactggg gcgggcaggg cgccgaaggc gttgacgagt
     3781 ccgccgacga ggtggccgat aggcaccagc acggcggaca ggccggagac cgcatccatc
     3841 gccacgttgg cgaccgtcgc gatgatgtcg agagtgccga ccgcggcgcc gccgtcctct
     3901 ccgagcgtgg agatggcgtg caggatgggt tccacaccgt cggccgcatg gcggagtacg
     3961 tcgcccaggg tctgggcggc attgatcaat aggttcaggc cggtggcaag ggtgtgcgca
     4021 ccgagctcct tgagcggtcc gagtagtccc tgggcctcct cgatgagtcc gccgaggcca
     4081 gacccggcct tggccttgag ttcggggccg tacagaacag cgaggttgcg gccgtactcc
     4141 agcgcggtgg tcaggtacgg ggtggcaccc gccatgccgc gcgtcaggag tcgggtgacc
     4201 cactccaggc ccggtgccat gccctcgtac agtgcgagcc cggtctgccg ggcctgggtg
     4261 cgcagttgcg tcatcgcgcc cgtcagaccc tgaccacgcg aggcagtgat ggtcgccgca
     4321 gccccggtct gccgtacggc tacggatagg gcgtcgaagg actcggtgcc ctggtgggcg
     4381 agggccgctg ctccggagag cgcgggcttg ccgaacgcac gggtaactcc ggcggcgaag
     4441 tccttctggg acagttcgtg ttcggccttc gacaggccat cgatgaccac gcgcaagcca
     4501 cggaaattcc cctgagcgtc ccatgcttgg atgcccaggt ccttgagccc gttcttcatc
     4561 tgcggcgtcg gtgccgcgag gttcgcgaag atccctcgaa gcgatgtgcc cgccgtctgc
     4621 ccgagaatcc ccgccttgcc gagcatgccg accgcggcgg cggtgtcctg gagcgagacg
     4681 ccaagcgcgt tcgccactgg ccccgcgtac cgcatcgagt agtagatatc ggtgatggag
     4741 cccgaggcgt tgttggccgt ggccgccagc gtgtccgacg ctctcgaagc ctgatcagcg
     4801 ccgagaccga actggtccat gatgtcgccc aaatatcggg cggacgtggc ggcgttgacg
     4861 tcggcagctg ccgcgagctg gagcgatgcg cgtacggcgt cgatggactg gtccgcgcgg
     4921 aagccagcct tggacaactc gaccatgccc tcggcggcat cggccgcggt cgagcccggc
     4981 agggtcagat cgttgccgag ctcctgcgcc acgacggcgg cgcgcttcat ctgcacggcg
     5041 gttgccgagg tgacggcccg gaacaggttc atctgccgct ggtagcggtt gccctcctcg
     5101 accattgcgc ccgcccccag cagcaggctg ccgccggaaa gcaagttggt ggcggatatc
     5161 ccgcgccgac ctgcaccgga cacggcacgc tggagtcggg acatggagcg tgccccgtcg
     5221 tcgccggccg cccgcaggct ggcgcgggcg gccgaggcgc gggcggtgat cctgttcagc
     5281 tcgcctacag ctgcacgcgt cgagcggttc agcgcggcga attggctggc caaccgggcg
     5341 ccgttggcgt ccagacgggc cagggagcgg ttggcggcgt cggtacgatc ggcgaaggtg
     5401 cgtgcctgac cggaggcagt acgaaatccc gcgatcaggt cgcgaacctc ggcacgcatc
     5461 gccacggtca gggtgaaccc ggccaccgcc ttgggcctcc ttccgtctta cgcggttgat
     5521 caggtgttgt cgcggtgcag cccgcgaggg agaagctgga tcttcacgcc gtagccggag
     5581 cggtcccccg gcacgtggtc gcgctcctgc tcgatcagct cgcagccggg acagcgcaga
     5641 gtgtctgtga cgtaggcgtg cgggtctcca ccgcgcttgg cgtcccactc ctccagccgt
     5701 gtgtggcact cggggcacat cgcccgctgc cactccgccc aggccagcgc cttggctcgg
     5761 tccagctcgg tccaccggcc gtccccgccg agaaattgcg agtggggaat ggcgtacgca
     5821 gcgcacagct ccagctcgga cctcagctgt gcgtcacgac tcagcctttt cccagctcca
     5881 ccctgctctc ctgctggacc tgccagcctg catcccatag ggcgttggcg tccggtgccg
     5941 accacgtgtt cagcagttcc tcggcctcct ttcggctcat gccgtcaaga gaagccgctg
     6001 agacaagtgc cgcagggaat gtgtccgggt tgaacacggc cccctcctgg gcctgctgtt
     6061 cggtcggcgg gtgttgggag atcagctcct ccagcgcagg acgcggcaag gcgaggaagg
     6121 tgaggaagtc cgaggcgctg tccagggcgg taccggcttc ctccaatgcg gtggcggcgt
     6181 cggctgcccg ccgcgaggcc gcctcgtcgt cggggttggc ctcggccagg aagcgggctc
     6241 gctgagcgga ctgttcggcc tcttcgaacc gttggcgcag ctgatcgtcg tcgcagatac
     6301 ggagcgtgtt ctgggcgcgg gggcggcgac gcaggcgatc catcttggcc gcccaggccc
     6361 cctccgccga cgtctcacgg ggaggggacg gtcgcttggc cggtgtgggg cgcgacatgc
     6421 tcagtcctcg tcaccgtgct cgtggacagt ggcggtggcc gcagtgctgc tcacgacggt
     6481 gacgtcgacg tggtcgccgt caccctggcc gcgctcgtgg tcgtcgtcgc agttctcgtc
     6541 cggcttcaga agagtgtgat agtcgccctc gggcaccggg gcgtcgagcg agggctcttc
     6601 tgtgatcgtg aagtcgacct tgaacttggc agcctcgttg ccggtgctgt acgtcgcggc
     6661 acgggtcgca acctgcacgg ggaacacgtc caccgaccgg gagccaggga tatcgccctt
     6721 gcggagcagc acgacatagc ccttggcgcc cttgggaagc tgctgctcga tggcgtcgga
     6781 gaaccggtcc tcgtagaagg tcagcgagct gttctcggcc ttatcgttgc ccgggatcga
     6841 agagttgaag gtcgagccca tgtccggcgt ctcgatgggg tcgttctcca gtgcccagcc
     6901 ctcgatgtcc gagacggcct gggtgaggtc gaaccggttg ggctcggaga tctcccggcg
     6961 agtcggccgc ttgggatcgt tgaccttctt gagccagtag atcttggaga ttccacgccg
     7021 caggaatcgg gtctgagtag acggcttctt cagggacaca ggtccgctcc cacttccggg
     7081 gcagcgtccc atgccaaggc cctgcccctt gaggttcaaa ggggttcgcc tggcctgagg
     7141 acctagcgtc cgcgcgggcc tccgcggtga gggaaagcgt tcacgcagct ggggtcacgg
     7201 tgatcgtgaa ccgctgcacg taagacacga tagcgcctga cgccgacacc gagggctcgc
     7261 ctccggcttc gtaggtcaac tcccggtcaa tggcacggcc ttcgggaatg cgcaggtcgt
     7321 ggctccagca accgtcggac cggccgacga cgccgacgcg cacgcggtcg gccagccatt
     7381 ccacctgatc gactcgttcc ccgaccgagg tgatctggta ggaccaggcg gcatcggcgt
     7441 gccagtccca gagcggcggg cccgtgaact cggcgggcag cgagtcgagg atggtgtacg
     7501 gaatggatgc gacctcccat ccggttcttc tttgcactcg ggggagttcg ccgatgccgc
     7561 acggtcggcc ggtggcgtgt tccaccaggg cggcgagcgc gcgggtcacc ggcaggcggg
     7621 cgatcacggc agcaccccgt ccgccagggc ctggatgaag gcgggctcgg tctgtctgaa
     7681 agcgggctcg atgtgcggga acggcggttg ccggtagtgc ctgccgatcg aatccacgcc
     7741 gacgaaccca tactccagcc gccgggcctg cggcgtgtcg gagaacacct cggcggtcac
     7801 ctcgccgccc ccggtgcgca tccgaacgtc ccacgaggcg cgatactgcc ccgtgatcac
     7861 gttcgggccg ggccgtccgc tcgcgttccg ttggatgcgg acccgcagca gcatggcgtg
     7921 gtgacgggtg atcgtccgtg tgcgggcgcg ggcggccgga cccatccgtg ccagcgcggc
     7981 ggccagcgcg atcgggtcgc ggaaggcgac cgcgtccggg tgggcattgg ggtgcgggtt
     8041 cgccggggcc atcagtcgat cacctgaact cggacgatcc gcaccacgct gtaggtgccc
     8101 accgctccgt cggagaagcg gaaccggcgg ccgaccagct gcgggtcgcg cggccctcct
     8161 cgccggacgg aaccggcgac gcgcaccacg tcgtcacgcc gcagcaccgg ggcgtcgacc
     8221 ggcagcacgg cctggtagtc ggtggtcggt ggctcgacgg cgaccgaccc gcccaccggc
     8281 ttcgtgatgg cagggcgccc gagcggcatc accgcgccga ggccatccca gaccagctcc
     8341 tcgtccggca caggcggcac caacctgccc gtggtctcgt ccagcacgtc gtccgtacga
     8401 cccgcgctat cccgccacac ttccagcttg tcgtccaaga tgcgggcgag gacccgccgc
     8461 gcaccgtcca cgtcaaagac cacgggccca ctccccgagt tgggtgagca tggccttggt
     8521 gagcgagtgc ggctccgtgc cgagatcggg acgggcaagc gccgcgcgct ccagcgcctc
     8581 ggggtcgatc gcgtccagga agatcgcagc ggctgggccc ggggcaggca cgtcagcgat
     8641 cgcgacgcgg gccaagccgt cgaaggcgag actgtcgagg tgctcggagt cgaggatgag
     8701 gtgcggtggc tcgcccgtgt ggtggctaag cgtgtagctg gtcagggctc ccgggtcgat
     8761 ccgctgtccg tcgatctcga tcttggcctt cggccccctc gcggtgatgc gtacccggtg
     8821 cgtggtctcg ttgctgtcgt ccatgcaggc gacgctaagt gcgctgtcgg acaagcctga
     8881 tcaggtgctg cccgttgcgg gccgcttgtg ggcgagaagg tgttccgtcg tcgtggcccc
     8941 ggattctgct gcctgtaaga gctctctttc caggggcgtg ggcatgtgtc cctggtcgag
     9001 tcctgccgag tagacggccg cgtacaggat tctctccgcg gggggcttga ggcgttctcg
     9061 gcaggatggg tgagcgagca cctctcgggc gacatacccg ttgcggcaac ttgctgcttc
     9121 cggcaggagg cgggtcgtga cggcggtggc gagtgcgggg tcagtctcgg tgaggtcgag
     9181 agcggtcagt ccgaggcgag tgcggaacag gtccagttcc gcagtcgtgt ccaagttgag
     9241 gtagttcctc accatcgccg tcatgatggt ctcgtcgttg attccagaca ggtgtcggca
     9301 aagggcggca aggcatgagg cgacggagtg ttcccaaggt tcagtcggga cgctctctcc
     9361 caagaaggcg taggcgccat cggggtctcc ggcaaggcat cgtaaaagga cttcgacttg
     9421 gcggccgtcc aggagccgat gtccaactcc gcggtgtcgg cgtgcctggg atcgggctcg
     9481 gttccaggct cctgccgcca ccagggcccg ggttccgtct ccgagcagga tggtccacag
     9541 ccactggtga agctgttggt gctcctcgtc cgttgtggtc aggtccttga agcagatggt
     9601 gtggccgtcc acttccgcac ggccgcgggt tcgggccgcc tgaacgaggg catcgagcag
     9661 gcggtaggcg ccgttggcgt ctccgtcccg gatgaggagt cgggcgatgt tgactaccgg
     9721 ctccagggcg taccgggcct cctgtgcgct caggggctgt gcgcacaggt agacctcggc
     9781 gtggcgccag cacagggtgc gtgccaggtc gggcataccg cagtcgctgg cgatcagggc
     9841 cgccttgttc tgcgctgccg ctgccaggct cagcttcccc tcatgctcgg cggagcgggc
     9901 cagatcgctt atctccctca cccgctcggc gagtggaggg cacgctgggc gagggcgcgc
     9961 tatcagtggg aagcgtcgcg ctatctggct ggcgtccaca tcactgccac tcgatgacga
    10021 tccggttcag cgggttgtcg aaagtgaatc ggcccggctt ctgctccggg gagggggcgt
    10081 cgagcggtcg gatttcgaag gcgacgttgc gggtccggaa gtcggagtcc caggtgcgta
    10141 ctgcctcggt gacgcgttcg gtgagatggt cggcgtcggg gccgtggccg atgactccga
    10201 actcgtacag cgtggcgcca tcctcggcgg tgtggtcggc cttgcgccgg gtgaggtagg
    10261 tcagcgtgcc cttgtcgaat gtggcggtcg agctggcgta ggggttggtg agcagaccgc
    10321 tgtcgatggc ttcacgcttg gcgggcatac ggctcaggcc gttggggagt gcgcaggtaa
    10381 gccacagctc cagccactcc ggggactcgg gccctcggaa ggtcacgccg gtccatgcct
    10441 cggctcgcgg ctggttcagg acgtcggcga gggcatctgt gtccacggtc tggtcgccgt
    10501 tggtcaccag ggtcacgctg ccgtcctcgg tcagcgggac gaagatccgt gggtcgtcgg
    10561 cgatgcccct gcgcagcggc atgaaagtgt tcatctcgga gccgacgctg cgccagcgcc
    10621 tttcggcgtc gcgttcgaag gcgatcgagc gggagacgct gccgcgcagc cgcagggggg
    10681 agagcagtcg gccaccgggg gcgagctggt cgagccaggc aaggggcacc gcgtgggcgc
    10741 cgacggtcgc cacgatccgg tcgtaggggg cgttggcggc gtacccctgc gcgccgtcgc
    10801 cgaggatgac ggtgacgttg cccaggccgg cggccttcag gccgatgcgg gcaccttcca
    10861 cgatgtcgtg gtccacgtcg agggtggtga catgcccctg ctcgcccaca aggtgtccga
    10921 gcaatccggc gttgaagccg gttccggcgc ccagctccag taccttcatg ccgggctcga
    10981 cgtggagctg ttccagcatc agggcaacga ttccgggttg ggaagcacag ctgatcgacc
    11041 gaccggcact gtcgtacttg gtgtccaccg tggtgttgga gtacgccttc tccaggggcg
    11101 cttgggggac gaagaggtgg cggggcacgg cccgcatcgc ttgctccacc cgcgcggtgc
    11161 ggatgctgcc gtcctggacc agttggtcta cgaggtgggc acgcaggtca tcggggctgg
    11221 tctcgatggt gtcactgttc accccggtga cagtagtggc cgcctcaccc gtgctgggcg
    11281 tggacgcggc ggtgtcgttc gttcccataa ctacctcttt cgccagtgtt gacaaggcgc
    11341 tttggtcctc acgcgggagg cccaagcggt tccagtggaa gatcagatga tgggcgagca
    11401 cggcgcgcag gccccgctcc agtcgtcctc ggcggttcag gtgcgcgagc tgctggcctg
    11461 cccactcgaa ggtggtgagc cagtcggtga ggtacgccag tcggccgtcg gcaaccgggc
    11521 tgctgtgcgg tcccacgtcc accgtcatga gccgacgtac ggcgacgcgg tgccgttgta
    11581 acagtgcgcg gtcggggtgc tgccgttcgg cctccacccg ggcccaaaca tcgccctgct
    11641 cgtaccagtc gagtccggca gctcgcagac acgcgctgaa cagcacgatc gccagctccc
    11701 ggcgtccaag aaccggggag cctggattct gctgctgaca ggcgagttgg tccagggcgt
    11761 ggcggctgtc acggtggaag aattcgtggg cgagttccat cccgtccggg ccgccgaagg
    11821 ctgccgtctc cggttcgtag atgcccggca cccactcgcg caccgctcca tctgcgacca
    11881 gggtgtcgag agcctggtcc aggtacgttg ggtctgccgg gtccgggcgg tagcgcaggc
    11941 gccaggtcgg ggccttgcgg atgaaagacc attgccgcgt gccaccactg tccaggatgg
    12001 gtcgaaggtg agcgacggcc acgcgttcgg catcgggcca gtcggtgaac tcgatgacgc
    12061 gctgaggcca ctcgtcgtcg ggcacagggt tccctccctc tgcgactagt tgatcaggag
    12121 acaggcgttc cacacggcgg atgtgccttc ctgcatgctg tgcagagcca tggcgatacc
    12181 tgcggcgcct tcgagaagcc cgatggcggc cgcaccttgc gggggcgcca gcaaggagtc
    12241 agccaggact tggggaccgg cagggacgag ccgttgcagg agatgtggaa gggcctgcgc
    12301 caagccgggg ttgatcgcgt ctgctgcggc gagctgggtg aggtggacga gcccggcgaa
    12361 gccgtggcac agcgaagcgt ccgtggtctg gtcgagctgt cccgggtcgg tcactgcgcg
    12421 taggagcgtg tcttcagcca tgtgctggcg cgcggtgtca cccaaagcga gggcggcgag
    12481 ctgctgggcg cgggcgatgc cagcggcgcc gtagcaccac gacggtcggg acggaccgat
    12541 gcccgggtcg cctgtgcgca gttgttcgcg ggtgatccag tacggccacc agggaccggc
    12601 caggccctgc tgctgccacc gatcgagcca ggagcagatc cgttcgatcg ccttgctctg
    12661 ccccggagcg gtgatgccgt ggaacgttgc cagggacagg gcggccagtg gcccggcgat
    12721 gccgtgcgcc atgccgttgt tgccatgtcc gcgggggaag tccgtgctcg gggcgcccga
    12781 gggtgacagt gcgctccacc agccgggcag caactcctcg ccgtctttga tgggctcggt
    12841 gagtcgtacc aggtaggcga tcacctgccg cgctaggtcg gtgtggacct ctcggcacat
    12901 cagcaaggcg gccatgccgg acaggccccg gatcgcgtcg aactcggcca gagccggcgg
    12961 ctccccgcgg tcgatgcgtg cgtgcgcggc cgccaaccgt gcctggacag tggcggccag
    13021 gtgcttgtcg agcgtttcca gggcgcgggc gtaacggtcg ggccagccag tggcggcagc
    13081 gtggagggcg aaggtgagag ctgggactcc gtagaacggg tgactgtccg ggcctccgac
    13141 ggcgccccca gcggcggcgc aagccagcca gtcgtgagcg cgctgccagg aggcaaggcc
    13201 aatgcgggcc cgctcgatgt gcagcagtgc tacgccgacg gcgccgttgg ccagggactg
    13261 aggccaccag ccgtgcgtca ggttccatgt acgggcctgc cccggcgagg cgaggcggtc
    13321 ggcaatcaga tcaaccgccg tctgtacgtc gtggtcattc tggggggtga tcatgcgctt
    13381 cgtgccttcc aggcaagggc ggcggcgcgg gccagccgga tacaagtacg ctcatccgcc
    13441 ttgtcgatcc ccgcagcccg gatgtggtgg gcatgcagca gcgagtcaag aaccgcgtcg
    13501 gggtcggtac cgtcatcaca ggcgcgcagc cggtctccat aggcggtcag cacgcgggcc
    13561 cgtgccgccc aagttgcatg gatggcggtg ccgccggggg ctgcacgcag gcccgcccaa
    13621 tcacctgtcg ggtcggccag gctgagtgct tcggcgcgta ccgctcggtc cagcgggcca
    13681 gggtcggtga ggtgcccgtg gcggatcagc cagtccattc ccacaacggt gctgccagtg
    13741 aaggccgttg cggtggcgac gaggttcgcg gcggccaggg cctgcgggtg tggccgagtg
    13801 ggctgtgcga aggcggtgac caggacggcg gagtctgcgg cgaacaccgt ctcggccgcc
    13861 tccagcccgc ctgcggttcc ccaccggccg gtctccgggt aggaggtggc gaactgcacg
    13921 tctccgacga gcccttgtcg gcgaagctcc gtagcccact cggcaacgcg ggcggcgccg
    13981 gtggcgaagt ctccgacatc cgccagcgcg aggcgcaggc gcagatgcca gcgcgggtcg
    14041 cggtagcgcg tataccacca cattggcggc tgctcccacc gggcgaacag gccgggcaag
    14101 tgatggccga ggatctccgg gtgacgtttg gtgtggctgt agatcttggc catcagccac
    14161 cgggaggcgc cggggacgtg gccgtgttcg cgcgtcacca accgtgccgt agagaccggc
    14221 ggcgtcgcac gcgacagtgc aggatggtca gcttgcagcg gcacggtgat ctcgtgggcg
    14281 tggccgtcca accaaccgtc cgcaccgggt tgtgtctcgg tcagcaccgc cgactccgac
    14341 gtggccaggt gcgagcgcac aagctccagg tgcgccgcct cggtgaggtt cagcggcaat
    14401 gccctgtcgc cttcagtcaa tgctacccag tccggtacac ggctgcggtg ccgccactgc
    14461 tccagagcct cgcgccactg cggccacgcg gcacaacggt cgggaacgtc ggagcggtgc
    14521 aagcgccacc tggcgggaga cagaatcgtg cggccgtacc gcacacgggg caagaacggc
    14581 agggcgttgg ccgcacccca ggtgaagggc gtcaccacgg tggacgttgc cttggcgatc
    14641 tccaacagga atcgagccag cggcggggtg tgggcgcgca ggtcaagagc gtgaggcgcc
    14701 atcggctcca ggcgctgctg ccgggagaga gaggccaagt acagacgctg cgggtcgcag
    14761 cccacagcca gatcgtccag cgcaatgagc cctgcgccgc cgtcgacgcg atgctcggca
    14821 aggctgatca cgtcgggcag cacgtccggg gcccgggtga cgtgggtgtc gcaccgattg
    14881 agaggcgtga aggaaagctg gaccgggcgt gcacccgagt cgctcgtcgg caggtggatg
    14941 aacgcctttc tggcttgtgc ctgttcttcc gggtccagca agccgatgaa tcggccggtc
    15001 gtcgtgccga tgccgcgcga cgggctgacg acggcgaggg tgaactcacc ctgggcgacc
    15061 gccgcaatgt cgggagcttg gaggcggaac cggagctcca ggtggggcgg cagtcgtacc
    15121 cggtccggct cacctggagt caacgctccg acgagttcct catccaggtg gacctcgtcg
    15181 cgcccttcaa gggcagcctg ctgcgccaga gcgaaaaggc gccggtccct gccgctcacc
    15241 gcggtgccgg cttccggctc tgcgtccagg tatccgtcgg ggaaccccag ccctaggtcc
    15301 gcgtcgacca gatcgcgcac cgggacaaga gacccgatgc cgtacctctc gaaaaaccgg
    15361 ttgtggtaag acttccaggc tggcgaaccg tacggcaaag ggctgagacg ggccaacaat
    15421 gagacggcct cctccgctgc gcgggcaacc tggtgaggca ggacgagcgt gcagtccagc
    15481 cgcgcgtcca ccgcaaccgg ctgctccacc accgtgctga ccgcgagcat gtccgtacga
    15541 agcgcggcgc gcagcctccg cccctccacc ggtccggtgg gcacgttgtg tgcggccagc
    15601 ttgctctgga ccttttgcag ccgggccgtc agctgcgcaa catccgggac gtcctcgacc
    15661 ccggcccccg ctatctgttg catcaggtga tcgaaggcat cgaaggtgcc tgctggggcg
    15721 tgcagagcac tgagcagaac cccttggctg acgaggctgg tgacgaggct ctcgaccttg
    15781 gacagcgcca cctggtgaaa ctccgcgctc accttctcca ccagttcgcg gccccggagc
    15841 ggagcgcggg cggcttccac caccagccgt acagccgcgg tgtatcggag cgagacctcg
    15901 gcagcgggtt cctccgcgcg gccggagcgt ggggggtagg gcacgacgag gcgccctccc
    15961 cgcaagaacg cgcagttgtt caccaccagg gataagcgat ggagaaccgc cggacaggct
    16021 tcaagccgct tgatgacatc agcaagccag gtgccgtcgg cccgcacgaa ggcgcggtgc
    16081 tgatctcccc agaccacaag cggttcgtcg gcgaaggcca tagggacaac accggcgaac
    16141 agcccgaacg gagtcgccct tccgtgcatg cgcagcgcgt atcgcacgag ggcggaagca
    16201 gcgcgccgta cccgccgagc gtcctcgact tcgcctacgc acacggcatg aacttgccgg
    16261 gccagggccg ggctggcctg ctcgacggcc gccgccagct cttctctgtc ccaggcggct
    16321 tggagccacc cacgccaacg ggcaacccga tgaggggagc tgtccgcgag gtccggccac
    16381 gaggccaggg gaaggcggtg accggacgcg cgcaccatcg ccgttccggc gcaccggtag
    16441 ggcaagcagc tcttcgtggc catgtgcttc ctctcgtgag tccttccgtc ccggcgctgg
    16501 cttgtgagga agtcacctcc tcacaagcca gcgccgtaac tacggcgcgg ctgccatcag
    16561 gccacgctgg aggcgcatgg gctggagcag gtgctgccgc agccgtcgtc agtgaggttg
    16621 atcagcttgg cggagcgatc accggactcc aggacagtga tatcgagttc gaactcgtct
    16681 tccacgagac ctccagaggt cgagtcggat acgtcgcccc ggtcgaggcg gcgtctcgtg
    16741 cgcccagggc acatagggtt tgggtgtgct ctggggaact ggatgaacgg tcaaaggacc
    16801 caggcggtgc tcagaccagg gaaccgcgcg gagcgtagcg cttctctatg cctgacgatc
    16861 ggttcccggt cagctccagg tacgcaggcc gcgcccagct gtagaccgtt ttgagcctta
    16921 gcagtcaccg cgctttctgg acgtcacacc agttcgtccg taatggcgaa cactagatgt
    16981 accgaatatc cgggagaatc cggcgtgctc acctcatgtt tcaccccctg cggcaggatc
    17041 agcacatctc caaccctggt gactatctcc tcgggtgcac cggtggtttc cggccagaca
    17101 agccagcgtt tcgcaccacg catttgggtg atcacgccga gccattcgtc atcgtgtgcg
    17161 ccgagattgc ggtcgccagc atgtgactcg taggcggtac agatcacttg gtggcgcatt
    17221 atcgcggtca gtcgcagcgt cactgtgctg aaccatccgt cgctgcgaac gttcaggctc
    17281 tcgtagacgc gcgtacgttg tcgctcctga taagcatgcg caaccgcatc cttatcggac
    17341 tggcgatgga aatccatccc gtcaatgagc gcaacagtct ggctcgctgc cttcgcctct
    17401 cccaagggga gggagagacc ctcggtccat gcagcgtcaa acacctgctg gatgtgcacc
    17461 ggatggcttg ccgtgagcct cggccaaacc gcagttccaa ggcgcccgag gaagctgaag
    17521 gccactgctt gatgcgaatg agcatccatc ggccagtcct cctaggtcgc gtacaggtgt
    17581 cccctggatc cattcagcct cagcgacgcc ttgcaatcct tcccaaaggg tcccgggcca
    17641 cgggcgatca gcggttcatc cgacggatcg atgacctgag ttgcgtgaag aacctccccg
    17701 ggggtgagct cgctcagctt gcaagggtga atctcgacca cgccccgctc cgcattcaca
    17761 gcctggacaa gaacctcgtc gtcggagatc tccagctctg acggcacgaa catgagccga
    17821 aaagcccctc cgatctcatg ctgtttgagt acgtcatgca gctgctgcat gagattcgca
    17881 tgctgctcca cctggggttc gctggcgaga actgtcattt cttctccctt gtgagtgttt
    17941 ctttcgtgaa cccggtgcga gacctcgtgc atggtttcgc gccgggagat ttgataccgc
    18001 tcggggcacc gggacccggc atcaaccgat gccccgagcg gggtctattc gacggaccgt
    18061 ggtccgacgc gctgagcacg gtcttccagc ccctcgacca ggccggtcgt ctcattggcg
    18121 cggaggtggt gagagatgcg ggcggcagcc tcgatggcga ccgtgatcac ttcatggccg
    18181 tacgaggctt cgcggcgtgt ccgctggaag cggctggaca gcgacaggac ggcggccagt
    18241 tccccatcac ggccgcgcac cgccaccgcc agaaccaggc ccccgtcggc aacgccctgt
    18301 acccagccgc gacaccgtat agcggagcac tcagcggcgg catccctcca gacttcacgg
    18361 ccctggctga gctcctgcca ggcgaggaag acacgcgaga cggggtcatc tcccatcgcc
    18421 gctacccggg ccggcttgcg gtcagtggcc gcggagttga gtcgcgggtc ctcggccatg
    18481 cagatccgct gatcgtcaca acgccgttcg aggcggacag accgtacgcc ggttgtggcc
    18541 cgaagcgcgc tgagttgctg ccgcagttca cggtgaacga tcgcctggtg cgccgccctt
    18601 gccaggcgaa tcagcctcgg accgacaatg aactgctcct gttggtcggc ctcgaccagg
    18661 cccagctcct gcatagcgag aacgagtcga cgcaccgtgg gacgcttcag gccagtttcg
    18721 gaaatcaccg tttccagatg cgccggcccc tcttccagca cggcgaggat cgcagatacc
    18781 ttgttgagca caccgacttg gctctgcacc atatctggat cagtaatcgt catcatctcc
    18841 ccttgacagg ccagccattc gagcgcgcgg agcaccctcg gcctcatgac tgcattgttc
    18901 tccgtttgcc gacgctctaa atctccagcg cctcatcacg agaatacgat ccgccgcgtg
    18961 gacgcagctc cacacctgct tcattgagca tcgtgtaaat gaacccgaat gagcgccctg
    19021 taacttcact tatatccctg atgctcacgt cggggtcgct taaatagacg gcactccctg
    19081 ggccccggat agccgagcga ccggagcctt atccggtgcc ggtccgagta cgccgagctc
    19141 ccagccacga cggataagat gcgccggggt tttggcgccc accagtgcca tcagcgcacg
    19201 cacgtctctg cgtacgacgt ccagatgcac cctgccgttc gcagcgatcc atcgcagatc
    19261 ctgaccgcct gccaagccgc gcagaacttc gtgctgaccc ccgctgagca cgaggtccgc
    19321 accgtcattt gtgtgctcgg gcggggagat ttcccccagc gtgtaggccc agtgcacggc
    19381 acccggccgt tcgggggagc cgagcttcac caaggcgaac cgtaggcagt cgttcactct
    19441 ggatgtcccc acacccatct ccgcggccgc ttgtgccggc gtcataccgc tcgctatgag
    19501 ctgtagggct tcgcgctcgc gagccgatag cctccatcgg cccgacggtt ggctggtcac
    19561 aacgaccctt tctcgtttcg atacgtatcg gtgtactggc acgggatgac cggctcatgc
    19621 agcggtgtgc tccgtcagat cgccaaggtc cacagccgtg cagccgtgga gcgcgacgac
    19681 ctcgcggcag gcgagggtcc agggcagtcg cgggtcgtcg tacgccacga gcgtgaacgg
    19741 ctcaccgtgc tcgccgggca ccggcctgag agtctcgggc gcgtgcacca ccccggccac
    19801 gccccaggct gcggcgtgct ccaccagcac cgccacacac tccctccgca cggaaggacg
    19861 gctcagtact tcaagggcac agccatcgca tacaggcggt gtggccgtcc tctccccatc
    19921 tgcgaccggc ttgccgctgg tggcatgcag caagaacaga tgccgcccat cgggccggtc
    19981 atcagtgggc cggccgcaga actgacacag catgtgattc atcgccagcc gctgacgcaa
    20041 agcgtgcaca cgtccgagca gaggcgcgcc agccccgtgc ctgaccggca ccctgatcca
    20101 cagggcgcca cgacgacggt cggcgatacc gtattcgcct gcgtaaccga tgcccatacc
    20161 gccgcgaccg tgccgcgtcg tgatcacggc cggaggcgcg ttttcgcctg tccacgcagc
    20221 gatgtacggc acacgcacac cgcccgcgaa gtactgacgt ggtcgtggac gccgaggccc
    20281 agcactggga cggtcaggcg gcagccagcc ggtgggtgac gtgcactggt cccgacgcat
    20341 attcgtcctc tcggatgtgt gctcgttgcg ggtaaagccc ctcttcggcg gcctctagac
    20401 tccgcggggg aacgggatga aaacgccgaa gagggagtag aaggtccgca tcacacctgg
    20461 tctagccaca gcccctccct tcctggcagt tggagcaggg gcggcggcca gccctcacca
    20521 gacgtgagcg tggtccagtt ggcacggtca tgaagtgacg tcgatcggcc tggcccgagg
    20581 gaagccctcc gtcagttgtc gacttcctgg acgctggccg tcgagaccac cgccatcacg
    20641 gtctgatgcc tgtttcgcag cgcggataga gacgcagcgc ctcttccaga caggagataa
    20701 ggacgaccgc actgggcaac ttcagcggag ctcgttcggt gaggtgccac ggcggagtgt
    20761 cccagcggac tccgctagtc ggcggcagag tgatccgtgc gtcggcgcca gccatgacct
    20821 ggacgcccgc gagtgcggag acgtgtaccc cgctgccgcg tgcgaccagg aacgtgcccg
    20881 tctcgccaca caagaggcat ggcagagccg tacccctccg atccagccgg accagcgcag
    20941 atgtggcggc tttgcgcgga gtggtaaccg cgtcgaactt ggtgcaggcg gccaacaaga
    21001 ctgtgctgga gttacgggcg aaggcatgtt gcacctcgtg tgcgttcatc aactccgcgt
    21061 cgataaacag gggccagccg agtaggtccg catctgcgta tgtgtccact acggcgtccc
    21121 ggcctctcgg cggccacaca gaagtcgtca tcaaggggtc ccccaagggg tgtgcatcgc
    21181 cccgacacgg gagccatctt ccggagccaa tggttcaccg gacccgcccg cggcaatctg
    21241 gaagctggtc tccatcaggt cgcgatcgca ctgcttcccg ctgggcaccg cgccaccagc
    21301 acgctcaccg ctcagttgcc ggactgatat cagcgaagac ggagcatgga agctctggga
    21361 gtggatgctg acgctcattg ccgccctcgc ggccagcgat ttcgcttctc atacgtcatg
    21421 cactcacgga ctccctgaca ctgctcattg gtagggcgca tacgtggtca ccacctgagt
    21481 agtcgcttga tcgctcactg cgattaagct ggacgaggtg tgcgctgggt caccagctgt
    21541 ggatgaactt actgtgacca agcgggcaaa aaaactgaca cagagtacga gttgcacacg
    21601 cccaaccacg tgggagcacg gcatggcgcc acagaagcga tcgcgctccg agacgggaac
    21661 actgactgcc ggtcagggtc cgccagcccg cactgcgagt ggcatcgtct gcggccatct
    21721 actcaagatc atccgcgagc gcattccgct gactcagtcc cggctggccg aagaactcgg
    21781 gatcgacacg acgaccgtcc agggctggga aacaggccgt cgttccctag cggctatctc
    21841 atccgcgcaa ttcctgcgtc tgaagcgaca tctgctagga cgcggtgcgg agccaacgct
    21901 tctgcctctc ttggatctcg cagtcgaggc cgactccgtg atcgagtact cgctcaacga
    21961 cacgctcaac agtgacgaca tcacccagca cccgctgcac agctgggtct ttacccgggc
    22021 atcgactcac atgatcgctt gggccctgac cggtgagcag cccacgattc tccccaaagc
    22081 ccccgcgtcg actccccgac ggagaggccc tacgcctggc tcaccactcc tgccaacccc
    22141 ccagcgagac aagctgttcg ccaatctccg ccgcacagcg gagatcgctg accgggtggg
    22201 ggaagatggc tcgcttctgc gccgacaggc gctctacctg tgtgcctacg acaccagcgt
    22261 cgacacccat tcctggctcg ctgacatgcg ggaacgccgt caaccgccac tgcgtcacgc
    22321 atcgtggaca ccagcctggt ccgacgccag gtcggtagca acgtccctga cccgctacgg
    22381 agacagcgag acgttgcaga cattcatcga gcggggcatg ggaggagacg ctagcgagat
    22441 ggccaacctc aattactggg cgcactggct gggtctcgac ccggtgcccc gtgcaagcga
    22501 cgcgttcatg agcgacgtgg acggccggtc ctgggaggcc ctcccgctcc ttcgcaacct
    22561 tgccgaccgg cttgatccgt cactgggcgc ggtggacttg aacatccact cggtgtgggc
    22621 gctgatcagc tcgaagcccg gtgttctgtc agctgaccgg gaactgcacc gcgacttgac
    22681 ctcccgagtc gaccgcctgc tcgacagtga tgtgatctca cgccagtcca ggcgtgagct
    22741 ggagaatgtg cattacggtc tgagactgag tagccggtga tccgcttgaa ggggacgatc
    22801 tgcatgactg atgaccaggc tgacaaggga actgtcggct acctgtttga gatgggtgcc
    22861 ctcaagcggg gaaagaggag tggctggtgg atcgcaggcg tcaaggaccc cgagaccatc
    22921 gccgagcact cgttccgcac cgcgatcatc ggcgcggtgc tggcgatgat ggaaggcgct
    22981 gacccagcga aggtcgccct tctgtgcacc ttccacgaca cccaggagac ccgtgtcggg
    23041 gacatcccgt ggatcgggcg ccgctacctc gaagccgcct cgaatgagcg ggtcactgcc
    23101 gatcaggtct cgaagactcc tcctgccgta gcggagggga tcaaggccgt ggtccacgag
    23161 tacgagaacg gcgactcact ggaggttctc gtggcacacg acgctgacaa gctcgagtgc
    23221 atgcttcaag gcatggagta cctggagcag ggttaccgca atgcccagga atgggtggac
    23281 accacgcggg cgaagctgaa gacgccctcc gcgctcgcgc tcgccgaagc ggcgcaaggc
    23341 atgtcgtcca tggaatggaa gcacacgtat ctgggctgac cagcacgtcg catctgcgcc
    23401 tggactgcgc cccgacccaa caaccaacct tccaagcaac tgtcggcctc gggcgttgcg
    23461 tgcttgagca gtccacccgg aaggggcagc taccggtaac gacgcgacgg aaccatgaat
    23521 gacgtcgcca gagtgttccc ctccccgtct ccatcctcgg ggtcatcggg ggccgaggtc
    23581 tgacatatgg cgtcgatctg tcgctcgatg ccgcgcagat tctcctgcaa gtccatggtc
    23641 acgacgccgt cgacggtgac cttcagcggg tcaccgagca gcttcgctcg cctctccccc
    23701 agcacctcca gcgccaccgc acgaaccgac cgcagccgga agtaccggcg ctccaggtcg
    23761 gctgagtccg tgtccggtcc gagctgcgcc agcagccacg accgctgaaa ctcatccacc
    23821 agcgtgtgtc cttcctctta gaacccataa cagaatgccc ctgatgaccc tcgaaatgtg
    23881 tcggcccgtc agctcatcgg cctgtgtatg cggtggggtg agcacagcca ccgtggatcg
    23941 cgtccgatga gttgcggacg aggtcggata ctgtccgcgc tgacttatta accgcacttt
    24001 ctctggctcg ctgaagagga gactcggatc cccttgtaag gagctgaaag ggcttagctc
    24061 ttgccgcagc tggcagctac cagggacgga cgaggacgag gccgaccttg ccaggccgta
    24121 ccgcgtgttc cacggcgtcg gccagctcgg cgaggccgta cgtagcggcc acgtcgaact
    24181 ggtccctgag ctccagtgcg atctgcttcg cggtggcgac gtcggattgc cgcctttcgg
    24241 tggaggcttc ggacggccac tggccaacgt tcttgccgcg catggtcagc gacttgctca
    24301 gcagcgttga tgcgtgcacc gagatcggct ccttggcgat cagtccgtaa ctgaccagct
    24361 tcccgcccgg tgacagcagg tccagaaggc tctccgccag cttcccgccg atggggtcca
    24421 acgccacact caccggacgg ccgccggctg ccttgcggac ctcgtcggcc cagcccggat
    24481 gctctgtcga cacgacaggc acgtccggga accgtttgcg cagctcggcg gcaccacggt
    24541 cactgcggac gacgttgacg agggggaagt tgtggaactg tgagacaccc gtcaccagcc
    24601 gcccgaccga tgagcccgca gcggtctgca ccaagcaacc gtcgtatccg aaggccaggt
    24661 gctcctgcgc ctcccggcgt agcatcaccg cggtgagcgg gttcgccagc atctgcgcgg
    24721 cgacctcgtc cgacaactcc tccggtacgg cggcgaccaa atcggcgtcc gccacgatcc
    24781 actgcgccca cgcccccggt tgggggaaga ccgttacccg gccgccgacc tcgacccccg
    24841 gcgcaacgcg cgttcccggg ccgatcgcct ccaccacgcc ggtgacctcc gtcccggctg
    24901 ggaccggctg tgcggcattc cctgggtatg cctcgatggt ctggagatca ccggggtgca
    24961 ccgtgaagac cgaggcgcgg ataaggacct ggccgtgctc gggcgtcgcc gggtctggtt
    25021 cctcgatgac ggtcaggacg tcggcgggtg acccaccacg ggtgtggacg acacgacggt
    25081 tcatgattct cctctttcgc cctggatcat gcgacttggc cgccagccga cgtcccgcag
    25141 cagcgggggc ttccactgag tgcgcggtcc agctgcctca gtggcccgct ctcacgcagt
    25201 cccctggtca cgctcgcacg gtgggtaaac agcagcacag ccgattgagc cgaccgggtg
    25261 atgagcctca cgaagcgccg ctccataagc cttgccttta tgcgggggca gcccgccacc
    25321 gagacgttcc ggtgacgggc cgtaggtcac ggcgatgccg aagtggaccg cgaacgacgc
    25381 ggcggcggct tcttcgtact gcctcctccc gcctcctccg ggtccgggtc gaccgtcttc
    25441 tctccggtcg gatccggctc gccgaccgcg attggctgcg atccgggtcc ctcaggcgga
    25501 acctcccacg cgtcaaggtt cgccaccagg gcagcgaggc gcggttcggg ctcctcacca
    25561 ggcaggagga tcagctcctc ccgcgtggcc gggtcctgca cgtacacggc ggctttcagt
    25621 cgaggcaccg gcatcacaag accttcgcca cgatgtgcgc gtccggggtg tgcatgaccg
    25681 gcatgccgac cgccgcgccc ttggtgtaga tctgcactgg gtcgtcctgg accccgcggg
    25741 tgatgatgag gcccggcgcg tcctcgcgga tgatctccgg gttcgtgcca cgcgagagca
    25801 ccagcgcctc ggccgtcaca ccgatctgcg tctgcgccca cttctcccgg tccgggggca
    25861 ccagaatcca caggtcctcc ggcagcacct tgcgcggctt accgtccacc cgcacctgcg
    25921 ccttgtagaa cgtgatcggc ggcagcgagt agttgcctcg caccacgttg atctgctgcg
    25981 gggtgagcgt cgccgtcggc gtggtcgacg ggttcacgct gccgtagtac gccgccctgt
    26041 acgcgttgtt cgccgccagg tacgagaacg tcttccggct ggtgatgacc agttccggct
    26101 ccggagcgcc gatgtcgtcc aggtgctgaa tccaccgcag ctcatccgcg atcggatccg
    26161 acgccgggtc ggaccacggc cgcgcggcga ctggcatgtt ctcggcgggg acgttccagt
    26221 ccacctccag cgtcagcccg ttctcctgca ccagctcgaa cttgccgtcg gccagcacgc
    26281 cgccggccgc aagctccagc cgcgaccgga tcgcctcgac gtgccgctcg acatcgtcat
    26341 acagcagctc gatcagccgg tcctggtcac tgccgtgcga tgcctccagc agaatctgct
    26401 cctgctcgga cacgatcagc ttctggccca gcgcgggcag cgcgccctca cgggatgtct
    26461 gcc
//
