LOCUS       NZ_LJSN01000005        22223 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces noursei strain JCM 4701 scaffold5, whole genome shotgun
            sequence.
ACCESSION   NZ_LJSN01000005
VERSION     NZ_LJSN01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1304482)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method :: SPAdes v. 3.6; SMRT Analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891315.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 20:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,947
            CDSs (total)                      :: 8,851
            Genes (coding)                    :: 8,489
            CDSs (with protein)               :: 8,489
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 362
            CDSs (without protein)            :: 362
            Pseudo Genes (ambiguous residues) :: 0 of 362
            Pseudo Genes (frameshifted)       :: 118 of 362
            Pseudo Genes (incomplete)         :: 301 of 362
            Pseudo Genes (internal stop)      :: 23 of 362
            Pseudo Genes (multiple problems)  :: 74 of 362
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 610155
            Orig. end                         :: 632378
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJSN01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22223
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22223
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22223
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12223](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12223)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(53..67)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.18"
                     /tool="antismash"
     gene            1076..1525
                     /locus_tag="AOB60_RS41165"
                     /old_locus_tag="AOB60_39895"
     CDS             1076..1525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510734.1"
                     /locus_tag="AOB60_RS41165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39895"
                     /product="DoxX family membrane protein"
                     /protein_id="WP_067348696.1"
                     /transl_table=11
                     /translation="MQTTWLTGAEWFAVLRIGLGLWWLESWRHKDKKTWFTGGGITWAA
                     GIAAKHRWPVVRTGFDRIVRPRPRLMAYVVAYAELALGLGLIVGLLTPIALVAGLLLNL
                     IYLVLMIHDWAEQGQNLMMALISAVGFCALCWQSWSLDAAWGLFL"
     gene            complement(1737..>1973)
                     /locus_tag="AOB60_RS46470"
                     /old_locus_tag="AOB60_39900"
                     /pseudo=""
     CDS             complement(1737..>1973)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS46470"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_39900"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="DAVYRPDRSENEERSAAQAHAGAGELPDAAHAAAVRASLASGQAA
                     GQVGLGRDEALNRAADEAEAAAVAAAKAAGWWV"
     assembly_gap    1974..2058
                     /estimated_length=85
                     /gap_type="within scaffold"
                     /linkage_evidence="strobe"
     gene            complement(<2059..2440)
                     /locus_tag="AOB60_RS46475"
                     /old_locus_tag="AOB60_39905"
     CDS             complement(<2059..2440)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS46475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_39905"
                     /product="hypothetical protein"
                     /protein_id="WP_180990449.1"
                     /transl_table=11
                     /translation="MSASDGEKSQLASLDTEAPSRGGVTTSEEALRNLRRQHLARGRSA
                     IDRARALCRFAGIGEQDARPVPTDPASKAATAVRLSAQALARVAEAPLDPAADARCARN
                     AAAAAAVVATAAQAHAGAGEGVG"
     gene            complement(2573..3034)
                     /locus_tag="AOB60_RS41180"
                     /old_locus_tag="AOB60_39910"
     CDS             complement(2573..3034)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713338.1"
                     /locus_tag="AOB60_RS41180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39910"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_073444320.1"
                     /transl_table=11
                     /translation="MSAGVEQHVIKPGWFTRNVFNRLVAALTRRGISVLGSQELAVRGR
                     KSGEWRCTPVNPLTVDGRQYLVAPRGHVQWTHNMRAAGGGELRIGKAARPFTATEVPDA
                     EKPELLRAYLKRWKAEVGVFFDGVGPDSSDEVLLGIAPKHPVFRITLGS"
     misc_feature    3116..3130
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            3167..3877
                     /locus_tag="AOB60_RS41185"
                     /old_locus_tag="AOB60_39915"
     CDS             3167..3877
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536568.1"
                     /locus_tag="AOB60_RS41185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39915"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073444319.1"
                     /transl_table=11
                     /translation="MSVIQGARERARREVTAAIKDEARRQLATEGAAKLSLRAVARELG
                     MVSSALYRYFPSRDDLLTALIIDAYDAVGEAAEHALAGAGAGAAPVARWTAVCRAVRGW
                     ALEHPHEYALIYGSPVPGYAAPQATTASAARVGLALIGVVEDAYPADVSPAPAAPSLPH
                     EVLDDAEELRKTLDVRLPAPVLAEIAAAWAELFGLVSFEVFGQFNRVIEARDAFFARAT
                     TRLAQNVGLAVGEE"
     gene            complement(3907..5598)
                     /locus_tag="AOB60_RS41190"
                     /old_locus_tag="AOB60_39920"
     CDS             complement(3907..5598)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575965.1"
                     /locus_tag="AOB60_RS41190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39920"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_102926985.1"
                     /transl_table=11
                     /translation="MLLVGLCAIVAALAETVTILLFAQLTDQALAQGSVSAFWNPAGTW
                     LTVALLGAVVGYLGNSLAAWTAERFLLRLRARVFTHLQTLPPHFFQRNRRGDLVERLTG
                     DVDAIEHLVVSGLVSACTAVFSTLFYGAAALWLRWELALATFVAAPIFFAATRRFTSRL
                     REVSRRLRAADGALTSVVEETLVNVVLTQAYNRQRDEETRLSREALRWLRASVASARLN
                     ALYEQLIEVLETLCVLTIIGLGAWEISAGRMSLGQLLAFAAFIGYLYPPIRSLGQLGLT
                     ATAATAAADRLLEILDARPAVIDPPPERTTPFPHRARGELAVQDVTFRYPNAAPGHHAL
                     AALSFTAQPGAFLVVTGPSGAGKSTLAALLLRFYDPDAGTIRLDGIEVDRLSLADLRRN
                     ITLLPQETLVLHDTIEHNIACGRDYPTPTHEEVVQAARAADAHAFVTALPNGYDTVIAP
                     ATAALSGGQLQRIAIARAMLRDAPVLILDEPTTGLDTLAAQRILGPLHRLAAGRTTLVI
                     SHDLDLATGADLILVLDEGHLTESGTHPDLLARGGLYTELFESGRG"
     gene            complement(6131..6325)
                     /locus_tag="AOB60_RS41195"
                     /old_locus_tag="AOB60_39925"
     CDS             complement(6131..6325)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS41195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_39925"
                     /product="hypothetical protein"
                     /protein_id="WP_073444318.1"
                     /transl_table=11
                     /translation="MTFKAFFPRNRINGGGGGGHGGRGGRGGWGYGYGGYGRGFGYGRG
                     FGYGYGFRGRGGRGFGFFR"
     misc_feature    6316..6330
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(6327..6341)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.48"
                     /tool="antismash"
     misc_feature    complement(6491..6506)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     misc_feature    6492..6505
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.17"
                     /tool="antismash"
     misc_feature    complement(6493..6506)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.76"
                     /tool="antismash"
     misc_feature    6493..6507
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.19"
                     /tool="antismash"
     misc_feature    complement(6494..6507)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            complement(6580..6756)
                     /locus_tag="AOB60_RS46480"
     CDS             complement(6580..6756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575967.1"
                     /locus_tag="AOB60_RS46480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_159030874.1"
                     /transl_table=11
                     /translation="MNALKAALWCVLALAAVVNAFTSLAFDGAQQVVLSVGTGTAVIAS
                     AVVLFLMRERRRP"
     gene            complement(7116..9695)
                     /locus_tag="AOB60_RS41200"
                     /old_locus_tag="AOB60_39930"
     CDS             complement(7116..9695)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536571.1"
                     /locus_tag="AOB60_RS41200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39930"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_102926700.1"
                     /transl_table=11
                     /translation="MTSENDRPDRSGGGAGEGPGRACDIATAAAAELDGRGVVVSWTRA
                     AERLLGYPATEVLGRSAVTLLAVPGDAARVAAVAHWAGDGWSGSVAARHRDGHAIQLAV
                     EVSPVITAATGGTAAPERWSVVALEEWRVPGGGVNQLMLEPFLAHAPVGMAVLDTDLRY
                     VWVNAVLERLIPLEQRLGRTVAQVLPRDEADAFEERMGQVLKTGKPVMDYEFRTRNYAD
                     PNQERAYSASFFRLAGPKGRGVGIWYMVIDVTERWRAQEGLALLNDASARIGSTLDVAR
                     TAQELADVAVPPLADFVAVDLLDSVLRGEEPEPGPVDSTPTMWRAGQRSVREGCPEAAL
                     AVGEAVRRQPWSAIGQCLLTGESVVEPLLNADSTWVAEDPRRADVVREYGFRSVMVAPV
                     RARGITLGAATFVRSRRQGLFDADDVRLAEELVARAAVCLDNARRFTRERTAARMMQRN
                     LLPHALAGGVALDVASWYFPADVPSGVGGDWFDVIPLSGARVALVVGDVVGHGIDAAAT
                     MGRLRTAVRTLANLDLPPDELLARLDDLVIGLMETRRDGGAGADDGTAATALGFMGATC
                     LYAVYDPVSRSCTMARASHLPPAVLAPDGVVDFPDLPAGPPLGLGAMPFESAELELAEG
                     SLLALYTNGLLETYDRDIGVGMARLGRALAEPGATLDEIGGNVVSALLTGPPSDDAALL
                     LARTHALDASQVASWDLSADPAVVAGARNLAGRQLAAWGLEPLRFTTELVVSELVTNAI
                     RHGSGPITLRLIRQDAALICEVFDTGSTAPHLRHARTTDEGGRGLLIVAQLTRRWGTRY
                     TANGKIIWAEQGQGEPPRESSGEAPRETPGKTPGDPAPPVPAPHDAG"
     misc_feature    complement(9807..9823)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: strong, score: 25.09"
                     /tool="antismash"
     misc_feature    9812..9825
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.69"
                     /tool="antismash"
     gene            complement(10001..12223)
                     /locus_tag="AOB60_RS41205"
                     /old_locus_tag="AOB60_39935"
     CDS             complement(10001..12223)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716662.1"
                     /locus_tag="AOB60_RS41205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39935"
                     /product="terpene synthase family protein"
                     /protein_id="WP_102926986.1"
                     /sec_met_domain="T1TS (E-value: 8.7e-83, bitscore: 275.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHPARLNPHLEAARAHSRKWAREMNMLEGSGIWDQRDLDAHDYA
                     LLCAYTHPECSQEALDLVTDWYVWVFFFDDHFLEKFKRTLDREGGKAYLDRLPAFMPMD
                     LDAPVPEPTNPVEAGLADLWRRTVPAMSLDWRRRFAESTEHLLNESLWELSNININRIP
                     NPVEYIEMRRKVGGAPWSAGLVECATGAEVPAAVAGSRPLRVLKDTFSDAVHLRNDLFS
                     YQRETEEEGELSNGVLVLETFLDCTTQEAADAVNEMITSRLQQFEDTVFTELPTLFAEK
                     GLDPAGRAAVLAYAKGLQDWQSGGHEWHMRSSRYMNGGGAGAPGSAAAPWSPLVFGGLG
                     TEGLGASAADLATALAAAGAQRVRRRSHAPYEKVGPPQLPDFCMPFTATRSPHLEAARR
                     NVVAWAHRMGLLQPQPGVPLSGVWDEDALVRFDVALRAAGPRPDATLDELDLGTQWLTW
                     ATYADDYYPAVFGRIGDVAGALATTRRLSALMPVDAPDRAPEPANALERALVDLWARTA
                     GPLDPDARRAFKATVDAMTASWLWELDNRVLHRIPDPVDYIEMRRATSGSGLAMGLSRL
                     GHGSRVPPEIYRSGPMRSLENAAADYACLLNDVFSYQKEIEYEGEVHNGILVVQNFFDC
                     DYPTALAIVHDLMTSRMREFQHVAQNQLPLLYDDFDLCAEARATLDGYVEELGNWLAGI
                     LAWHRECGRYRPEHLRHRPGTPGWTPGPTGLGTSSARLTEALGAAR"
     misc_feature    12427..12447
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.36"
                     /tool="antismash"
     gene            complement(12475..13311)
                     /locus_tag="AOB60_RS41210"
                     /old_locus_tag="AOB60_39940"
     CDS             complement(12475..13311)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536573.1"
                     /locus_tag="AOB60_RS41210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39940"
                     /product="alpha-L-glutamate ligase"
                     /protein_id="WP_073444316.1"
                     /sec_met_domain="RimK (E-value: 3.2e-06, bitscore: 23.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVGVISADPGHPLLAATAAVLRGDGHRVGFVGPDGVPLAGGGEP
                     VGVAAPGVLADVYLLKARTPQALALAGRLEGRGAPVVNSVAATTRCQDRVEMAAVARAA
                     GLPFAETLRTATVGELAAAGPDLAFPLVLKSRDSRRHDLVARVDTPADLAELAAARPDE
                     PVIVQEFTANSGWDHKLWVVGGQLFAARRRSELSPGGRGPNQPLPPAALPFAWIEAALH
                     IGAVFGLEVYGVDVLHAGAGAAVIVDINAFPGVRGQVGAPEALAALALRRAESGPA"
     gene            complement(13308..14234)
                     /locus_tag="AOB60_RS41215"
                     /old_locus_tag="AOB60_39945"
     CDS             complement(13308..14234)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536574.1"
                     /locus_tag="AOB60_RS41215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39945"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_073444525.1"
                     /sec_met_domain="RimK (E-value: 1.4e-09, bitscore: 34.0,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.9e-07, bitscore:
                     27.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLCFLVEEQYRHDGMPQDVIGQLRAWGHRVDVLWPGRSLIRMSE
                     LSGVVADGDHDAWVLKTVSGGPGLTLLEAAATIGLTTVNDVRAIRGVRDKALAAVIARA
                     SGLPVPMTYAAVRAEEFAEVPEAEFPLVVKPADGSSGRAVRLVERPEELAAGAGAMADG
                     TGDGMLIAQPYVPNSGTDLKVYCVAGDLYATERCSPLHPGRAVTERQVPLPAEVARIAA
                     EIGEVFGLDLYGVDVLLGPDGPVVVDINDFPSFRQVPDAVARVSAAVLRLARRGTDRAP
                     VPALPFIGHQRTPRPVAEAAGAVGGAR"
     misc_feature    14357..14371
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            15012..16286
                     /locus_tag="AOB60_RS41220"
                     /old_locus_tag="AOB60_39950"
     CDS             15012..16286
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578882.1"
                     /locus_tag="AOB60_RS41220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39950"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_102926987.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.6e-38, bitscore:
                     129.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLLPDGPVRDHAVLVEHGTFREVGPAARLLAAHRAGPAPIRLPG
                     HLLMPGFVDTHHHLTQSFGKAQSFGQPSEIFKTVWEPLEHALDEEGAYLSAKLAGLEAL
                     RGGFTTVADAGTRAPVDVAAIAKGTEEAGIRCVLGKIVSAGTGGPAHLARWHGHPLVHP
                     SLAIAVPEDATGPVIKRTADLCAEAGAVLQIHVNEHLASVERSLKSVGRRPVDYLHHLG
                     ALGPHTLGAHATLLTPTEMRQLADTGAAISYNPVASAWKGNAVAHATMLAALGVRFGTG
                     TDGTRGDGFRLVDAAETAQRLAYGLASGDSVCGAGHLWLEHATAGGADALGLGRVTGRI
                     AAGQAADYLLVDLAVPELTPSYDLRWELVRLAGRDQIRAVVVGGRLRIWEGWPPDWDAR
                     ALIARAAEVGPQVVKRAKIQRVEPR"
     gene            complement(16431..17966)
                     /locus_tag="AOB60_RS41225"
                     /old_locus_tag="AOB60_39955"
     CDS             complement(16431..17966)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544674.1"
                     /locus_tag="AOB60_RS41225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39955"
                     /product="MFS transporter"
                     /protein_id="WP_258018423.1"
                     /transl_table=11
                     /translation="MRSGRVPARAPVTCAMCLCVALVVGMVSAVNLAIPDLSAGPLHPS
                     AAAVVWVVDGYVVVFACLLVPAGALADRRGRKGTLLCGMAVFVLGSAVCAVAPHVGVLI
                     AGRMISGVGAAAVLPNTLALLVDGLSDGPRRRAIAVWAAMTGLAAVLGNVGGGAAIQYG
                     SWRALFVCVVPVAVGASVLVAVVAPVTGRHPGPVAPLAAVLFTGGFLALLNGFVSGPGE
                     GWLGPWVLGSFGVAGVLLTGWARCELRSARPLLDPRVFARPAVRAGAVGMAVLFLGMFG
                     LFYLNGQYLQYAKGYGPFGAGVRLLPMAAALLAGPRCGLVLERRCGRRGTVGTGMLVLA
                     GGLATVSAADAGTPYALYAVGAGLTALGCGTATPLLSHAMMSALPPEAAGVGSGLQSLT
                     RELGSALGIAVTGTLTAAVFTARLPAPLAGPGAPTTVAAAQAALGDLPDRGGELRTAVI
                     GAFTDGLHLATLALAAGVAVAAGAVFRWMPREGEAEAGTARASAGGGPVTRTG"
     gene            complement(17971..18753)
                     /locus_tag="AOB60_RS41230"
                     /old_locus_tag="AOB60_39960"
     CDS             complement(17971..18753)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572461.1"
                     /locus_tag="AOB60_RS41230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39960"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_073444313.1"
                     /transl_table=11
                     /translation="MEADDGGDGHRGGAVGDGPTRADRARRVAHVLRGQVVRGAFPGGV
                     LPDERALVAEFGTSRNAVREALGLLRDEGLVERRRGVGTVVVGRTYEHPLGELSGLAEV
                     LQRHGTVVNEVRAARIVRAPGAVARRLELPEGSRAVYLERLRRVDGMPLSLDCTYLIPE
                     VGEPLLALGPERLENRDVFELIERAAGRPLGSAEVAVRAVVADPATCAVLGMTAGGAVL
                     AVDRLTRLADGRPADLEFIHLRGDRLTLRARLDRVREG"
     gene            19021..19614
                     /locus_tag="AOB60_RS41235"
                     /old_locus_tag="AOB60_39965"
     CDS             19021..19614
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991130.1"
                     /locus_tag="AOB60_RS41235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39965"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_258018424.1"
                     /transl_table=11
                     /translation="MSTKSAPFDELDRKIVVALIENGRASFAEIGSAIGLSPTAVKRRV
                     DRLRETNVITGFSATVRPAALGWLTEAYVEVYCDSAAPPRRLAEVVRNHPEIAAAMTVT
                     GGADALLHVRATDVEHFEEVLERIRTEPFIRKTISYMVLSHLLPDSPEAGARRPSDDRS
                     ATRPEDQAAHQAAGRAGDGARVHPQPLRRAANQR"
     gene            19812..20720
                     /gene="ddaH"
                     /locus_tag="AOB60_RS41240"
                     /old_locus_tag="AOB60_39970"
     CDS             19812..20720
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572459.1"
                     /locus_tag="AOB60_RS41240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39970"
                     /product="dimethylargininase"
                     /protein_id="WP_102926702.1"
                     /transl_table=11
                     /translation="MTHPGGALTRAPRTPRARRYLLCRPTHFAVEYAINPWMREDADVD
                     TALALRQWEDLVRAYRDHGHTVETVRPAPGLPDMVFAANSAVVVGGRAFGSLFHAPQRR
                     PESHEYEIWFKGAGYDLHRPESPCEGEGDLVPVGRYLLAGTGFRTTRDAHAEVQEFFGR
                     PVISLQLTDPYFYHLDTALFVLDDDLPADGLPADGTSTGGNGAGDAGGAALAYYPEAFS
                     PGSREVLRQLFPDAVLATRDDALAFGLNSVSDGRHVFVAPRATHLIDQLTARGYVPVPV
                     DLSEFHKAGGGIKCCTQELRP"
     gene            20717..21940
                     /gene="rocD"
                     /locus_tag="AOB60_RS41245"
                     /old_locus_tag="AOB60_39975"
     CDS             20717..21940
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (32-354). E-value: 2.9e-102.
                     Score: 334.1. Matches aSDomain:
                     nrpspksdomains_AOB60_RS41245_Aminotran_3.1"
                     /codon_start=1
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524735.1"
                     /locus_tag="AOB60_RS41245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39975"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_102926703.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-115, bitscore:
                     382.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAPTKTRRSSASLIEAEAPVLAHNYHPLPVVISRAEGVWVEDV
                     EGRRYLDMLAGYSALNFGHRHPALIEAAHRQLDALTLTSRAFHHDRLGQFAGALAELTG
                     LDMVLPMNTGAEAVESGIKLARKWAYEVKGVPADQATIVVAGGNFHGRTTTIISFSDDD
                     EARANFGPYTPGFRTVPYNDLAALEAAIDDTTAAVLIEPIQGEAGVIIPDDGYLAGVRA
                     ATSRANCLFIADEIQSGLGRTGTTLAVEHEQVVPDVILLGKALGGGIVPVSAVVARREV
                     MSVLGPGQHGSTFGGNPLAAAVGTAVVDLLTTGEFQSHAADLGKVLHSGLTDLLGKGVT
                     AFRARGLWAGVDIDPALGTGRTISERLMSEGVLVKDTHGSTIRLAPPLTITEHELTTAI
                     AALGRVLA"
     aSDomain        20813..21778
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOB60_RS41245_Aminotran_3.1"
                     /evalue="2.90E-102"
                     /label="AOB60_RS41245_Aminotran_3.1"
                     /locus_tag="AOB60_RS41245"
                     /protein_end="354"
                     /protein_start="32"
                     /score="334.1"
                     /tool="antismash"
                     /translation="VISRAEGVWVEDVEGRRYLDMLAGYSALNFGHRHPALIEAAHRQL
                     DALTLTSRAFHHDRLGQFAGALAELTGLDMVLPMNTGAEAVESGIKLARKWAYEVKGVP
                     ADQATIVVAGGNFHGRTTTIISFSDDDEARANFGPYTPGFRTVPYNDLAALEAAIDDTT
                     AAVLIEPIQGEAGVIIPDDGYLAGVRAATSRANCLFIADEIQSGLGRTGTTLAVEHEQV
                     VPDVILLGKALGGGIVPVSAVVARREVMSVLGPGQHGSTFGGNPLAAAVGTAVVDLLTT
                     GEFQSHAADLGKVLHSGLTDLLGKGVTAFRARGLWAGVDID"
     gene            complement(21937..22161)
                     /locus_tag="AOB60_RS41250"
                     /old_locus_tag="AOB60_39980"
     CDS             complement(21937..22161)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572457.1"
                     /locus_tag="AOB60_RS41250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_39980"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_102926704.1"
                     /transl_table=11
                     /translation="MAEGTIPSAATLNGWRKSSYSDNEGADCVEVIDGHPHGIPVRDSK
                     APHGPAIVVPAGAWSAFVAAVKGEAFGGR"
ORIGIN
        1 tggccctcgc tgtaggcgag tttcagccgg gggaacttca ccagcacccc gctgaacagg
       61 aagtccatca tcgaggccat cgcgttgttg aagctcagcg acgcctgcac ggccggcggc
      121 gcgtccgggg aggccgccgg catctgcgac gacgacccga tgtgcatgtt caccaccgtc
      181 ccggtctcct cgcaggccgc gaagaacggg tcccagtagc cggagtggat ggacggcaga
      241 cccaggtagg tggggatctc actgaaggtg accgcccgga cgccgcgcgc ggcgttgcgc
      301 ttgatctcgg cgacggcgag gtcgatgtcc cacaggggga tcaggcacag cgggatcagc
      361 cgaccgccgc tgtcgccgca ccactcctcc accatccagt cgttgtaggc gcggacgcag
      421 gccagcccga cctccttgtc ctccgcctcg gcgaaggtct ggccgcagaa ccgcgggaag
      481 gtcgggaagc agagcgacgc ctcgacgtgg ttgacgtcca tgtccgccag ccgggccttg
      541 ggatcccagc agccgcgccg catctggtcg cgcgtgatgc cgtcgagcgt catctcgtcg
      601 cgggagaagc cgacggccgc gatgatgcgc ttgtacggga acagctgccc ctcgtactcc
      661 caccagtcgg tgatctggcc ctccgggtcc gtggtgaagc ggtacttgcc gccgacgtac
      721 gccagctcac cgatgccggc ggtgaggggt ttcgggccgc ggtcccggta cttccgcggg
      781 agccacgtct cgaagaggtg cgccggttcg atcacgtggt cgtccacgct gatgaccttc
      841 ggaagctccg ccgttccgct gttgtcgccg ttgccgctgg tcacgctcta cccccaactg
      901 ccgtgccggt gagtcacgcc ggcccaaaat ctgacgaccc atcagttcgg aggttaggag
      961 ttcccccctg cgaccacaag ggagggccgg aaactcgacc ccttgcgcgt tcgtacaccg
     1021 tccgctgaac tgacgctcca tcagatcccg tgcggggtcg agaggagcgg ttcgcatgca
     1081 gacgacctgg ctcaccggtg ccgagtggtt cgcggtgcta cgcatcggcc tcggcctgtg
     1141 gtggctggag agctggcgcc acaaggacaa gaagacctgg ttcaccggcg gcggcatcac
     1201 ctgggcggca ggcatcgccg ccaagcaccg ctggcccgtg gtccgcaccg gcttcgaccg
     1261 catcgtgcgg ccccgcccgc gactgatggc ctacgtcgtc gcctacgcgg aactcgcgct
     1321 cgggctcggc ctgatcgtcg ggctgctgac gccgatcgcc ctggtcgcgg ggctgctgct
     1381 caacctgatc tacctcgtgc tgatgatcca cgactgggcg gagcagggcc agaacctcat
     1441 gatggcgctg atctccgccg tcggcttctg cgcactgtgc tggcagagct ggtcactgga
     1501 cgccgcctgg gggctgttcc tgtgacggcg gcgaggggca actccgcccg ttacggcggc
     1561 gggtgggggc tccgcccata acggtgaggg atcggggcgg gcggagcgcc ggggtggaca
     1621 ccgggcgatc cgggcccgcc ccgacgggcg gcccgccccg ttccgcccct ctcccagggc
     1681 ctgtccgatg ggcccgaagg gtctgatggg tccgaagggg cagggtcgga cgggccttag
     1741 acccaccacc ccgccgcctt ggccgcggcc accgccgccg cctccgcctc gtccgccgca
     1801 cggttcagcg cctcgtcccg gcccaggccc acctggcccg ccgcctgccc actggccagg
     1861 gaggcccgca cggcggcggc gtgcgcggcg tccgggagct cgccggcccc ggcgtgcgcc
     1921 tgggcggcgc tgcgttcctc gttctcggag cggtcgggcc ggtacaccgc gtcnnnnnnn
     1981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     2041 nnnnnnnnnn nnnnnnnngg cccacgcctt cgccggcccc ggcgtgcgcc tgggcggccg
     2101 tggcgacgac cgccgcggcc gcggccgcgt tccgcgcgca acgggcgtcg gccgccggat
     2161 cgaggggcgc ctcggcgacc cgcgcgagcg cctgggcgga cagccggacg gccgtggccg
     2221 ccttcgaggc gggatccgtc ggcaccgggc gcgcgtcctg ctccccgatg ccggcaaaac
     2281 ggcacagggc cctcgcgcgg tcgatcgcac tccgcccccg ggcgaggtgc tgcctcctca
     2341 agttccgcaa ggcttcctcg gaggtcgtca ccccgccgcg ggacggcgcc tccgtatcga
     2401 gcgacgcgag ctgcgacttc tcaccatcgg atgcactcat gcccgcctcc ttgtccgttg
     2461 ggcccactcg ggctcgggcg caccgcggcg cggagccgtg tccgaggcgc cgacggtgcg
     2521 ccgggcaggg tgccacgcgc ggcgcgaaga gaccagggcc atgcccgacg ggtcaggagc
     2581 cgagagtgat gcggaagacg gggtgcttgg gcgcgatgcc gagcagcacc tcgtcggagg
     2641 agtccgggcc gacgccgtcg aagaagacgc cgacctcagc cttccagcgc ttgaggtagg
     2701 cgcgcagcag ctcgggcttc tcggcgtccg ggacctcggt ggcggtgaac ggccgcgccg
     2761 ccttcccgat gcggagttcg ccgccgccgg cggcgcgcat gttgtgggtc cactgcacat
     2821 ggccgcgcgg cgcgacgagg tactgccgac cgtccacggt gagcgggttc accggggtgc
     2881 accgccattc cccgctcttg cgtccgcgca ccgccagctc ctgggaaccg agcacgctga
     2941 tgccgcgccg ggtgagcgcg gcgacgagcc ggttgaacac gttgcgggtg aaccagcccg
     3001 gcttgatgac gtgctgctcg acgcctgcgc tcatggggat cctcccggag aagtgaaagt
     3061 gtgagcggtg ctctctctgt agagcagtgt gcacggtgcg gatccacaaa gcaagagcag
     3121 tgctctcgat attggtcgct gctcgctccg gtggcagact ggccccatga gcgtcatcca
     3181 gggagcgcgg gaacgcgcac gcagggaagt caccgccgcc atcaaggacg aggcccgccg
     3241 gcagctcgcc accgagggcg ccgccaagct ctcgctccgt gccgtcgccc gcgagctcgg
     3301 gatggtctcc tccgcgctgt accggtactt ccccagccgc gacgacctgc tcacggcgct
     3361 gatcatcgac gcctacgacg cggtgggcga ggcggccgag cacgccctcg ccggggccgg
     3421 cgcgggcgcc gcacccgtcg cccggtggac cgcggtctgc cgcgccgtcc gcggctgggc
     3481 gttggagcac ccgcacgagt acgcgctcat ctacggctca cccgtccccg gctacgccgc
     3541 gccccaggcc accaccgcgt ccgccgcccg cgtcggcctc gccctgatcg gcgtggtcga
     3601 ggacgcgtac ccggccgacg tctcccccgc gccggccgcc ccgtcgcttc cgcacgaggt
     3661 gctggacgac gccgaggagc tgcgcaagac cctcgacgta cgcctgcccg cccccgtcct
     3721 ggcggagatc gccgccgcct gggccgagct cttcggcctg gtgagcttcg aggtcttcgg
     3781 ccagttcaat cgcgtcatcg aggcccgcga cgccttcttc gcacgcgcca ccacccgact
     3841 cgcccagaac gtcggcctcg cggtcggcga ggagtagcac gacggggcgc gggacgccgc
     3901 ccccgttcag ccgcggccgc tttcgaagag ttctgtgtac aggccgccgc gggcgaggag
     3961 gtcggggtgg gtgccggatt cggtgaggtg gccctcgtcg aggacgagga tgaggtcggc
     4021 gccggtggcg aggtcgaggt cgtggctgat gacgagggtg gtgcggccgg cggcgaggcg
     4081 gtggaggggg ccgaggatgc gctgggcggc gagggtgtcc aggccggtgg tgggctcgtc
     4141 gaggatgagg accggggcgt cgcggagcat ggcgcgggcg atggcgatgc gttgcagctg
     4201 gccgccggag agggcggcgg tggcgggcgc gatgaccgtg tcgtagccgt tcgggagggc
     4261 ggtgacgaag gcgtgggcgt cggcggcccg ggcggcctgg acgacttcct catgggtcgg
     4321 ggtggggtag tcccggccgc aggcgatgtt gtgctcgatg gtgtcgtgca ggacgagggt
     4381 ctcctggggg agcagggtga tgttgcggcg gaggtcggcc agggagagcc ggtcgacctc
     4441 gatgccgtcg agccggatgg tgcccgcgtc cgggtcgtag aagcgcagca ggagcgcggc
     4501 gagggtggac ttcccggcgc cgctggggcc ggtgacgacc aggaacgcgc ccggctgcgc
     4561 ggtgaaggag agcgcggcga gggcatggtg accgggggcg gcattcgggt agcggaaggt
     4621 gacgtcctgg acggcgagtt cgccgcgggc gcggtgcggg aagggcgtgg tgcgctcggg
     4681 tggcgggtcg atgacggccg ggcgggcgtc gaggatctcc agcagccggt cggcggccgc
     4741 ggtggcggcg gtggcggtca ggccgagttg gcccagcgac cggatcggcg ggtagaggta
     4801 gccgatgaag gcggcgaagg cgaggagttg gccgaggctc atccggccgg ccgagatctc
     4861 ccaggcgccg aggccgatga tggtcagcac gcagagggtc tccaggacct cgatgagctg
     4921 ctcgtagagg gcgttgaggc gggcgctggc gaccgaggcg cggagccaac gcagtgcctc
     4981 ccggctcagc cgggtctcct cgtcgcgctg ccggttgtac gcctgggtga ggacgacgtt
     5041 gaccagcgtc tcctcgacga cggaggtgag ggcgccgtcg gccgcccgca ggcgtcggga
     5101 gacctcgcgc agtcggctgg tgaagcggcg ggtggcggcg aagaagatgg gggcggcgac
     5161 gaaggtggcc agcgccagtt cccagcgcag ccagagtgcg gcggcgccgt agaagagcgt
     5221 gctgaagacg gccgtgcagg cgctcaccag gccgctgacc acgaggtgtt cgatggcgtc
     5281 gacgtccccg gtcagtcgtt ccacgaggtc gccgcggcgg ttgcgttgga agaagtgcgg
     5341 cggcagcgtc tggaggtggg tgaagacccg ggcccgtagg cgcagcagga agcgttccgc
     5401 ggtccaggcc gcgagggagt tgccgaggta gcccaccacc gcgccgagca gcgcgaccgt
     5461 cagccaggtg ccggcggggt tccagaaggc actgaccgag ccctgcgcga gggcctggtc
     5521 ggtgagttgg gcgaagagca ggatcgtgac ggtctcggcg agcgcggcga cgatggcgca
     5581 cagtcccacc agcagcatcc agcggcggtc gcccttggtc agcggccaga agcggtggaa
     5641 cgcctcgacg gcgccgacgt ggcgggtcag gatgggtgct tcggtgggga gttgaccgcg
     5701 gattccggcg ggggcggggg cctgcggccg ctcctgtccc tgcggcggcg acgggggccg
     5761 cggctgcctc ggcgcctctt ccggtgtcgc gccccgtccc gacgcctgtg gcgtcgccgg
     5821 tgacggtggc tgcggcgggg tcggcgagcg gtcctgggtc ggtgccggtt cgcgctgccg
     5881 cgacgggtcc ggttccggct ccgggccggt ggactccggt acggggtagg gcagttctgc
     5941 cttacggggg tgcatggtcg ccacgtgtgg tgcgggccgt tgatcgcggg gtccggcagg
     6001 ccacgaggcc ggctcgcgtc gcacatgcga gcccgcctcg ggctgtgcgt cgggtccgtc
     6061 ggcccgaatc acatgtcagt gatcgtcagt tgtcgtgtgc cgtttcaccg gcacgccaac
     6121 ggacgggatg tcaccggaag aagccgaagc cacgtccgcc acgtccgcgg aatccgtagc
     6181 cgtagccgaa gccgcgtccg tagccgaagc cgcgtccgta gccgccgtag ccgtagcccc
     6241 agcctccgcg gcctccgcga ccaccgtggc cgccgcctcc tccgccattg atgcggttac
     6301 gggggaagaa tgccttgaag gtcatcttcg cctcctgaga attcggactg tgcgccgcgg
     6361 ccttcagccg gaccgtgctc tgtacggcga ttcggcgcgt tcccgccggg gcgtcccgtg
     6421 cggtgcgttc cggaggaacg atctgtccgc gacacttccg acactacgtc ggccatccat
     6481 ccccaacaag ggttttatgt gaaaattcag acatgcagta catgtcactg tgggtgggag
     6541 ggcggtcgct cgcggtcgac gcggtgggcc gaaaccgcgt caggggcgcc gcctttcgcg
     6601 catcaggaac aggaccacgg ccgaggcgat gacggccgtg ccggtgccga cgctcagcac
     6661 gacctgctga gcgccgtcga aggcgaggct ggtgaaggcg ttgacgacgg cggcgagggc
     6721 cagtacgcac cagagcgcgg ctttcagggc gttcatcggt gacggtgtcc ttccgggcgt
     6781 ggtggatccg aggggcacaa ggcacgcggg cacgtcgcgg acgccgcgtc agcgacggtg
     6841 accctgtgcg ctcgacccgt ccaccacgat gcccggcgcg cgggccgggg acgaggggga
     6901 gcgcccccgg atcgggggta catcgagctg cacccccgag gtacttcgag gtgcattgag
     6961 gtgtgccgcg gtgcgtcgtg cagcgccact gcccgttcgt tggcccggaa gggacgtgaa
     7021 ctgttcggcg ttggcaggat gttgacgggg cgtgggccgt ggcggcggcg acagcagtgg
     7081 cggacgcccg gcggctgacg ccacgtcagc ctgcgtcagc ccgcgtcgtg cggggcgggg
     7141 acgggcggcg ccggatcccc cggcgtcttc cccggtgtct cccgcggcgc ctcccccgag
     7201 gactcccgcg gcggttcccc ctgcccctgc tccgcccaga tgatctttcc gttggccgtg
     7261 tagcgggtgc cccagcggcg ggtgagctgg gcgacgatca gcagcccgcg gccgccctcg
     7321 tccgtggtcc gggcgtgccg caggtgcggg gcggtgctgc cggtgtcgaa gacctcgcag
     7381 atcagggcgg cgtcctggcg gatcaggcgc agggtgatcg ggccgctgcc gtgccggatg
     7441 gcgttggtga ccagttcgct gacgaccagt tcggtggtga agcgcagcgg ctccagcccc
     7501 cacgccgcca gctgccgccc ggcgaggttg cgggcgccgg cgaccaccgc cgggtcggcg
     7561 gacaggtccc aggaggcgac ctggctggcg tccagggcgt gcgtgcgggc cagcaacagc
     7621 gcggcgtcgt cggacggcgg gccggtcagc agcgccgaca cgacgttccc gccgatctcg
     7681 tcgagcgtcg cgccgggctc cgcgagggcg cgaccgagcc gggccatgcc caccccgatg
     7741 tcccggtcgt aggtctccag caggccgttg gtgtagagcg ccagcaaact gccctcggcc
     7801 agctccagtt cggccgattc gaagggcatc gcgcccaggc cgagcggcgg tccggcgggc
     7861 aggtcgggga agtccacgac gccgtcgggg gcgaggaccg cgggcggcag atggctggcg
     7921 cgggccatcg tgcaggaccg gctgaccggg tcgtacaccg cgtacagaca ggtggcgccc
     7981 atgaatccca gcgcggtggc ggccgtgccg tcgtcggcgc ccgcgccgcc gtcccggcgg
     8041 gtctccatca gcccgatcac caagtcgtcg aggcgggcga ggagttcgtc cggcggcagg
     8101 tccaggttgg ccagggtccg gaccgcggtc cgcagccggc ccatggtggc cgcggcgtcg
     8161 atgccgtgtc cgacgacgtc cccgacgacc agcgccaccc gcgcccccga cagcgggatc
     8221 acgtcgaacc agtcgccgcc caccccgctc gggacgtccg ccgggaagta ccaggacgcc
     8281 acgtccagcg ccaccccgcc ggccagcgcg tgcggcagca gattgcgctg catcatccgg
     8341 gccgcggtgc gctcgcgggt gaagcggcgc gcgttgtcca ggcacaccgc ggcgcgggcg
     8401 accaactcct cggccagccg cacgtcgtcc gcgtcgaaga gcccctgccg ccgggagcgg
     8461 acgaaggtcg ccgcgccgag cgtgatgccg cgggcccgga ccggcgccac catcaccgac
     8521 cggaacccat attcccgcac cacgtcggcc cgccgcgggt cctcggccac ccaggtgctg
     8581 tcggcgttca gcagcggctc caccaccgac tccccggtga gcaggcactg cccgatcgcc
     8641 gaccacggct gccgccggac cgcctcgccg accgccagcg cggcctccgg gcacccctcg
     8701 cggaccgacc gctgcccggc ccgccacatc gtcggggtgc tgtccaccgg cccgggctcc
     8761 ggctcctcgc cgcgcagcac agagtccagc agatcgaccg ccacgaagtc ggccagcggc
     8821 ggcaccgcca catcggccag ctcctgcgcg gtccgcgcca cgtcgagagt gctgccgatc
     8881 cgggcgctgg cgtcgttcag cagcgccagc ccttcctggg cccgccagcg ctcggtgacg
     8941 tcgatgacca tgtaccagat gcccacgccc cgccccttgg ggccggcgag ccggaagaac
     9001 gacgccgagt aggcccgctc ctggttcggg tcggcgtagt tgcgggtgcg gaactcgtag
     9061 tccatgaccg gcttcccggt cttcagcacc tgccccatcc gctcctcgaa ggcgtcggcc
     9121 tcgtcccgcg gcagcacctg ggcgaccgtg cgccccagcc gctgctccag cgggatcagg
     9181 cgctccagca ccgcgttcac ccagacgtag cgcaggtcgg tgtccaggac ggccatgccg
     9241 accggggcgt gggccaggaa cggttccagc atcagctggt tcaccccgcc gccgggcacc
     9301 cgccactcct ccagcgcgac caccgaccac cgctcgggcg cggccgtccc gccggtcgcc
     9361 gcggtgatca ccggcgacac ctccaccgcc agttggatcg cgtgcccgtc ccggtgccgg
     9421 gccgccaccg acccgctcca cccgtccccc gcccagtggg ccaccgcggc gacccgcgcc
     9481 gcgtcccccg gtacggccag cagcgtcacc gcgctgcgcc ccaggacctc cgtcgccggg
     9541 tagcccaaca gccgttccgc cgcccgcgtc caggagacca ccaccccgcg cccgtcgagc
     9601 tcggccgcgg ccgcagtggc gatgtcacag gcccggcctg gcccctcgcc cgccccgccg
     9661 cccgacctgt ccggccggtc attctccgag gtcatctcat cgccagtccg tcgcagccgg
     9721 ttctgtcccg ggcgctgccg ccgccgcggc gtggctgccg tcgcggtcca ccggcgtcct
     9781 cggcggtgtc acaggcgccc gcaccatgcc cattttagaa gcaatacgac ataggggatc
     9841 acttgcctcg ggtcgaccct tcctgcggat cagtcgccct gcgcggcccc ccgcccgcgc
     9901 tccgtcacca ccccgcccgt acgtccacct cgacggcgtc acggacgcgg agggacccgg
     9961 cgcgccacct gaccgccggg ccccgtcccg cccccttctc ctagcgggcc gccccgagcg
    10021 cctccgtcag gcgtgccgac gacgtcccca ggcccgtcgg ccccggcgtc cagccgggtg
    10081 tgccgggtcg gtggcggagg tgttcggggc ggtaccggcc gcactcgcgg tgccaggcga
    10141 ggatgccggc gagccagttc cccagttcct cgacatagcc gtcgagggtg gcgcgggcct
    10201 cggcgcagag atcgaagtcg tcatagagga gggggagttg gttctgcgcg acgtgctgga
    10261 actcgcgcat gcgggaggtc atcaggtcgt ggacgatggc cagcgcggtg gggtagtcgc
    10321 agtcgaagaa gttctgcacg acgaggatgc cgttgtggac ctcgccctcg tactcgatct
    10381 ccttctggta cgagaagacg tcgttgagca ggcaggcgta gtcggcggcg gcgttctcca
    10441 gcgaccgcat cgggccgctg cggtagatct ccggcggtac ccggctgccg tggccgagcc
    10501 ggctcaggcc catggcgagg ccggagccgg aggtggcgcg gcgcatctcg atgtagtcga
    10561 ccgggtccgg gatgcggtgc agcaccctgt tgtccagctc ccagagccag ctggcggtca
    10621 tcgcgtcgac ggtggccttg aaggcgcggc gcgcgtccgg gtccagcggc ccggccgtac
    10681 gggcccagag gtcgacgagg gcgcgttcga gggcgttggc cggttccggg gcccggtcgg
    10741 gggcgtcgac cggcatcagg gcggacagcc gccgggtggt ggccagggcg ccggcgacgt
    10801 cgccgatccg gccgaagacc gcggggtagt agtcgtcggc gtaggtggcc caggtcagcc
    10861 actgggtgcc gaggtcgagc tcgtcgaggg tggcgtcggg gcgcggaccg gccgcgcgca
    10921 gcgcgacgtc gaagcggacc agggcgtcct cgtcccagac gccggacagc gggacgccgg
    10981 gctgcggttg gagcagtccc atccggtgcg cccaggcgac gacgttgcgc cgggccgcct
    11041 ccaggtgggg gctgcgggtg gcggtgaacg gcatgcagaa gtcggggagt tggggcggac
    11101 cgaccttctc gtacggggcg tgggagcggc ggcggacccg ctgggcgccg gccgcggcca
    11161 gggccgtcgc caggtcggcg gccgaggcgc ccagcccctc ggtgcccagc ccgccgaaga
    11221 ccagcggcga ccagggggcc gcggcgctgc cgggcgcgcc cgccccgccg ccgttcatgt
    11281 agcggctgga gcgcatgtgc cactcgtggc cgccggactg ccagtcctgg aggcccttgg
    11341 cgtacgcgag gacggcggcg cggccggccg ggtccaggcc cttctcggcg aagagcgtcg
    11401 gcagttcggt gaagacggtg tcctcgaact gctgcaaccg cgaggtgatc atctcgttga
    11461 ccgcgtccgc ggcctcctgg gtggtgcagt ccaggaacgt ctccagcacc agcacgccgt
    11521 tgctcaactc cccctcctcc tcggtctcgc gctggtacga gaagaggtcg ttgcggaggt
    11581 ggacggcgtc ggagaaggtg tccttgagga cccggagggg gcgggagccg gcgaccgccg
    11641 ccgggacctc ggcgccggtc gcgcactcca ccagccccgc cgaccagggg gcgccgccca
    11701 ccttgcggcg catctcgatg tactcgacgg ggttggggat ccggttgatg ttgatgttgg
    11761 agagttccca gagggactcg ttcagcaggt gctcggtgct ctcggcgaac cgtcggcgcc
    11821 agtccagcga catcgcgggc acggtgcgcc gccacaggtc cgccaacccc gcctcgaccg
    11881 ggttggtcgg ctccggcacg ggcgcgtcca gatccatcgg catgaacgcc ggtagccggt
    11941 cgaggtacgc cttcccgccc tcccggtcca gggtgcgctt gaacttctcc aagaagtggt
    12001 cgtcgaagaa gaagacccag acgtaccagt cggtgacgag gtcgagcgcc tcctgggagc
    12061 actccgggtg ggtgtaggcg cacagcaacg cgtagtcgtg ggcgtcgaga tcccgctggt
    12121 cccagatgcc ggaaccttcc agcatgttca tctcccgggc ccacttcctg gagtgcgccc
    12181 gcgcggcctc caggtgcggg ttcagccggg ccggatgcgg catgtagaag cgcggcaagg
    12241 tgaagggttg cgacgtgggc tgcggctgcg tcaccgttgg tggcctctcc cgataccgat
    12301 gcccctccgc acggacgggg tgtacggaag gagggcgcgc cgaagcaccc catggacggc
    12361 gcagccctac cccgaggttc gccgccgtag gctcgtcggg tcacaccccc gctgaactgg
    12421 cactctttcg agttgagttg gcgatgaagg ggtgtgacgc atcggtcgca tgggctatgc
    12481 gggaccgctc tcggcccggc ggagcgccag cgccgccagc gcctccgggg cccccacctg
    12541 gccgcggacg cccgggaagg cgttgatgtc cacgatcacc gcggcgccgg ccccggcgtg
    12601 cagcacgtcc acgccgtaga cctccaggcc gaagaccgca ccgatgtgca gcgcggcctc
    12661 gatccaggcg aaggggaggg cggcgggcgg cagcggctgg ttcgggccgc gcccgcccgg
    12721 ggacagttcg gagcggcgac gggcggcgaa gagctgcccg ccgacgaccc acagcttgtg
    12781 gtcccagccg ctgttggcgg tgaactcctg gacgatcacg ggctcgtcgg gccgggcagc
    12841 ggcaagctcc gccaggtcgg cgggggtgtc gacgcgcgcc acgaggtcgt gacggcggct
    12901 gtcgcggctc ttgaggacga gcgggaaggc gaggtccggc ccggccgccg ccagctcgcc
    12961 gaccgtcgcc gtccgcagcg tctccgcgaa cggcagtccg gccgcccggg ccaccgcggc
    13021 catctccacc cggtcctggc aacgggtcgt cgccgcaacg gagttgacga ccggcgcgcc
    13081 ccggccctcc agccggccgg cgagcgccag cgcttgcggc gtgcgcgcct tgagcagata
    13141 gacgtcggcg agcaccccgg gcgcggcgac cccgaccggc tcccctcccc cggcgagggg
    13201 cacaccgtcc gggccgacga agccgacccg gtgaccgtcc ccgcgcagca ccgccgccgt
    13261 cgccgccagc agcgggtgcc cgggatcggc gctgatcacg ccgaccctca tcgtgcgccc
    13321 ccgaccgccc cggccgcctc cgccaccggc cgcggggtcc gctggtggcc gatgaacggc
    13381 agcgccggca ccggagcgcg gtcggtgccg cgccgggcca gccgcagcac cgccgcggag
    13441 acccgggcga ccgcgtccgg cacctgccgg aagctcggga agtcgttgat gtcgaccacc
    13501 accggcccgt ccggccccag cagcacatcg accccgtaca ggtcgaggcc gaagacctca
    13561 ccgatctcgg cggcgatccg ggcgacctcg gccggcagcg gcacctgccg ttccgtcacg
    13621 gcccgtcccg ggtgcagcgg ggagcagcgc tcggtcgcgt agaggtcgcc ggcgacgcag
    13681 tagaccttca ggtcggtacc ggagttgggg acgtagggct gggcgatcag catgccgtcg
    13741 ccggtgccat cggccatcgc cccggccccg gccgccagct cctcgggccg ttccaccagc
    13801 cgcaccgcgc gccccgagct gccgtccgcg ggcttcacca ccagcgggaa ctccgcctcg
    13861 gggacctcgg cgaactcctc ggcccgcacc gccgcgtacg tcatcggcac cggcagcccg
    13921 ctggcccgcg cgatcaccgc ggcgagcgcc ttgtcccgta cgccccgtat ggcgcgtacg
    13981 tcgttcacgg tggtcagtcc gatggtcgcg gcggcctcca ggagggtcag cccgggcccg
    14041 ccggagacgg tcttgaggac ccaggcgtca tggtcaccgt ccgccaccac gccggacaac
    14101 tcggacatcc ggatcagcga acggcccggc cagagcacgt ccacccggtg cccccacgcg
    14161 cggagttgac cgatcacgtc ctgcggcatg ccgtcgtggc ggtactgctc ctccaccagg
    14221 aagcagagtc tcatcgatgc acccttgtat tgccgcacgt ccacccgtat cgccaacccg
    14281 cccaccacag cagcggacgt cctccccatg tcgccgtacg cacaccgtcc gcccggcgga
    14341 aacatgacgc accaggatcc catgtggcga tcaggcgctc ggccatggcc cggccgccgc
    14401 cccggaggtc gcgtttcggc gacgttacgc caccggacgg gacctcggca cacgccgtga
    14461 gctgggacgc gccacgcccc tcgcggggtt gcgccactcc tccccgacct cgccaaatcc
    14521 cgtatgtcga aagccttgtt ccgttttatg gcccgaccct agggtcgggc cacccagcgc
    14581 ggccgacccg atcacgggcc cggccgcgcc tacgtacgcg gcgacggaag caggcgagcg
    14641 ggttggcgaa cgagcagcgg ggccgggagc cccaggaggc cggggctccc ggcgggtgtc
    14701 cggatgcgca acggccggac ggcgaacggc cggacgcgca gcggccagac ggggaacggc
    14761 tcgacggcac ccggagcgca gcggcccacg acggggcatc cgggccggca tccggcgcgg
    14821 cgcccgaagg ggccggcccc cgcggcggcc tcggtcggcg cggcttcctc gccggggtgg
    14881 ccgggctgac cggcgccggc ggcctgctcg gcggaccggg cgccggcacc gcctccgcgc
    14941 agccccggga cgcccacccc gccctccgcc ccgaccactt cgccggcccc cgccagctcc
    15001 tcgtcccgga ggtggtgctg ctgccggacg gcccggtgcg cgaccacgcc gtcctcgtcg
    15061 agcacggcac cttccgcgag gtcggcccgg cggcccggct cctcgccgcg caccgcgccg
    15121 gccccgcccc gatccgcctg cccggccacc tcctgatgcc cggcttcgtc gacacccacc
    15181 accacctgac ccagagcttc ggcaaggccc agtcgttcgg ccagccgtcg gagatcttca
    15241 agaccgtctg ggagccgctg gaacacgcct tggacgagga gggcgcctat ctgtcggcga
    15301 agctggccgg gctggaggcg ctgcgcggcg gcttcaccac cgtcgccgac gccgggaccc
    15361 gggcgccggt cgatgtggcc gcgatcgcca agggcaccga ggaggccggc atcaggtgcg
    15421 tcctgggcaa gatcgtctcc gccgggaccg gcggcccggc ccatctggcg cgctggcacg
    15481 gccatccgct ggtccacccc tccctggcca tcgccgtccc cgaggacgcc accggcccgg
    15541 tcatcaaacg gaccgccgac ctctgcgccg aggccggggc ggtgctccag atccacgtca
    15601 atgaacacct ggcctccgtg gagcgctcgt tgaagagcgt cggccgccgc ccggtggact
    15661 atctgcacca cctcggcgcc ctcggcccgc acaccctggg cgcgcacgcc accctcctga
    15721 cgcccacgga gatgcggcag ctggccgaca ccggcgcggc gatcagctac aacccggtgg
    15781 ccagcgcctg gaagggcaac gccgtcgcac acgccaccat gctggccgcg ctgggcgtcc
    15841 gcttcggcac cggtacggac ggcacccgcg gcgacggctt ccggctggtc gacgcggccg
    15901 agacggccca acggctggcc tacgggctgg cctcgggcga ctcggtgtgc ggcgccgggc
    15961 acctgtggct ggagcacgcc accgcgggcg gcgccgacgc cctcgggctg ggccgcgtca
    16021 cgggccggat cgccgccggt caggccgccg actacctcct ggtggacctc gccgtccccg
    16081 aactcacccc ctcctacgac ctgcgctggg aactcgtccg gctggccggc cgcgaccaga
    16141 tccgcgccgt ggtggtcggc ggccggctcc gcatctggga gggctggccg cccgactggg
    16201 acgcccgcgc gctgatcgcc cgcgcggcgg aggtggggcc ccaggtcgtc aagcgggcca
    16261 agatccagcg ggtcgagccg cggtaggtcc ggccgggcgg gggtgtggct acagggccag
    16321 ggggacggcc atggggagac agccgggggg ggagagagac agccggggcg agacggctgg
    16381 gggacggccc cgcctcggct tctgcccgac gaccacccgt ggcccgacga tcaccccgtg
    16441 cgcgtcacgg gcccgccccc tgcgcttgcg cgcgccgtcc ccgcttccgc ttccccctcc
    16501 cggggcatcc accggaagac cgcccccgcc gccaccgcca cccccgcggc cagcgccagc
    16561 gtcgccaggt gcagcccgtc cgtgaaggcc ccgatcaccg ccgttcgcag ctccccgccc
    16621 cggtccggca ggtccccgag cgcggcctgt gccgccgcga ccgtcgtcgg cgccccgggc
    16681 cccgccagcg gcgccggcag ccgggcggtg aacaccgccg cggtcagcgt cccggtcacc
    16741 gcgatcccca gcgcgctccc caactcccgg gtcaggctct gcagtccgga gccgaccccg
    16801 gcggcctccg gcggcagcgc ggacatcatc gcgtgcgaga gcagcggggt cgcggtgccg
    16861 cagcccagcg cggtcagccc ggccccgacg gcgtagagcg cgtacggcgt accggcgtcg
    16921 gcggccgaca ccgtggccag cccgccggcc agcaccagca tcccggtgcc gaccgtgccg
    16981 cgccgcccgc accggcgctc cagcaccagc ccgcaccggg gccccgccag cagcgccgcc
    17041 gccatcggca acagccgcac accggcgccg aacggcccgt accccttcgc gtactggagg
    17101 tactggccgt tgaggtagaa cagcccgaac atgcccagga acagcaccgc catcccgacc
    17161 gccccggccc ggacggcggg gcgggcgaac accctggggt ccaacagggg ccgcgcggag
    17221 cgcagttcgc accgggccca gcccgtcagc agcaccccgg ccaccccgaa cgacccgagc
    17281 acccacggcc cgagccaccc ctccccgggc ccgctcacga acccgttgag gagcgccagg
    17341 aacccaccgg tgaacaggac cgcggccagc ggcgcgaccg gccccggatg ccgccccgtc
    17401 accggcgcga ccaccgccac cagcaccgac gcgcccaccg ccaccggcac cacgcacacg
    17461 aacagcgccc gccagctccc gtactggatc gccgcgcccc cgcccacatt gcccagcacc
    17521 gcggcgagcc ccgtcatggc cgcccagacc gcgatcgccc ggcggcgcgg cccgtccgac
    17581 agcccgtcca ccagcagcgc gagggtgttc ggcagcaccg ccgcggcccc caccccgctg
    17641 atcatccgcc ccgcgatcag caccccgacg tgcggcgcca ccgcgcacac cgccgagccg
    17701 aggacgaaca ccgccatccc gcacagcagc gtgcccttgc gcccgcgccg gtcggccagc
    17761 gccccggccg gcaccagcag acacgcgaac accaccacat agccgtccac cacccacacc
    17821 accgccgccg cggacgggtg caacggcccg gcggacagat ccgggatggc cagattgacc
    17881 gccgagacca tgccgacgac cagcgccacg cacaggcaca tcgcgcacgt caccggcgcc
    17941 cgcgcgggca cccgacccga ccgcaccggc tcacccctcc cggacccggt ccagccgcgc
    18001 ccgcagcgtc agccggtccc cgcgcagatg gatgaactcc aggtcggccg gtcgcccgtc
    18061 cgccagtcgc gtcaaccggt ccacggccag caccgcgccg cccgccgtca tccccagcac
    18121 cgcgcaggtc gccgggtccg cgaccaccgc ccgcacggcc acctccgccg accccagcgg
    18181 ccgcccggcc gcgcgctcga tcagctcgaa gacgtcccgg ttctccagcc gctccggccc
    18241 caacgccagc agtggctcgc ccacttcggg gatgaggtac gtgcagtcca gggacagcgg
    18301 catcccgtcc acccgccgca gccgctccag atacaccgcc cggctcccct ccggcagctc
    18361 cagtcggcgc gccaccgccc ccggtgcccg cacgatccgc gccgcccgga cctcgttgac
    18421 caccgtcccg tgccgctgca acacctcggc cagcccggac agctccccca gcggatgctc
    18481 gtaggtccgg ccgacgacca ccgtccccac cccgcgccgc cgctccacca gcccctcgtc
    18541 gcgcagcagc cccagcgcct cccggaccgc gttgcgcgag gtcccgaact ccgcgaccag
    18601 cgcccgctcg tcgggcagca cgcccccggg gaacgcgccc cgcaccacct gcccgcgcag
    18661 cacatgcgcc acccgccgtg cccggtccgc ccgcgtcggc ccgtcgccga ccgcgccgcc
    18721 gcggtggccg tccccgccgt cgtccgcctc catgcccgcc ctcctcacac cccgccgcgc
    18781 cgcctccgtt gcgccccgac gagcggacgc cgggccccga cgctaagcaa gccccgttac
    18841 ggcggagtta cgccaccacc attgacctgc acagacgcct gacctgggga tttatccgcg
    18901 cgcccgggcg ctgcgccacc acccgccgat cccggttacc ttgactgcac tcccccgccc
    18961 cggggacggg taacgacccg gcccggggtc gcgcggagga gaggaagaaa gggccgcacc
    19021 atgagcacca agtccgcgcc gttcgacgag ttggaccgca agatcgtcgt cgcgctgatc
    19081 gagaacggcc gggccagctt cgccgagatc ggctcggcca tcggcctgtc ccccaccgcc
    19141 gtcaaacgcc gcgtcgaccg cctccgcgag accaacgtca tcaccggttt ctccgccacc
    19201 gtccgccccg ccgccctggg gtggctcacc gaggcgtacg tggaggtcta ctgcgacagc
    19261 gccgccccgc cccggcggct ggccgaggtc gtccgcaacc acccggagat cgccgccgcg
    19321 atgaccgtca ccggcggcgc cgacgccctg ctgcacgtcc gcgccaccga cgtcgagcac
    19381 ttcgaggagg tcctcgaacg catccgcacc gagccgttca tccggaagac gatcagctac
    19441 atggtgctct cgcacctcct cccggacagc cccgaagccg gcgcccgccg tccttccgac
    19501 gaccgttccg ccacccgccc cgaggaccag gccgcccacc aggccgccgg ccgggccggc
    19561 gacggcgctc gggtccatcc tcagccgctc cgacgcgcag caaaccagcg ctagccagcc
    19621 gccacaagca gcattcctgc gtacctgcgc agcattcatt tcttgtggcc ggaatccgcc
    19681 gcttcgtacc gtgtattgcc cccggtgacg acccatgacg gaccgtacgg acccacgaag
    19741 cgtgcggacc gtcgtgccga ccggcgggca gtggatacgg accccaggaa gcggaggccc
    19801 tttctgtgcc catgacccac cccggcggcg cgctcacccg ggcgccccgg accccgcgcg
    19861 cccggcgcta tctgctctgc cggcccaccc acttcgccgt cgagtacgcc atcaacccct
    19921 ggatgcgcga ggacgccgac gtcgataccg cactcgccct gcggcagtgg gaggacctgg
    19981 tccgcgccta ccgcgaccac ggccacaccg tcgagaccgt ccggccggcc cccggcctgc
    20041 ctgacatggt cttcgccgcc aactccgccg tcgtcgtggg cggtcgcgcc ttcggctcgc
    20101 tcttccacgc cccgcagcgc cgccccgagt cccacgagta cgagatctgg ttcaagggcg
    20161 ccggctacga cctccaccgg cccgagtcgc cctgcgaggg cgagggcgac ctcgtccccg
    20221 tcggccgcta cctcctcgcc ggcaccggct tccgcaccac ccgcgacgca cacgccgagg
    20281 tccaggagtt cttcggccgc ccggtgatca gcctccagct gaccgacccg tacttctacc
    20341 acctggacac cgccctcttc gtcctcgacg acgacctccc cgccgacggc ctccccgccg
    20401 acggaacgag caccggcggc aacggggccg gcgacgccgg cggggcggcc ctcgcctact
    20461 accccgaagc cttctccccc ggcagccgcg aagtgctccg ccagctcttc ccggacgccg
    20521 tcctggccac ccgcgacgac gccctggcct tcggtctcaa ctcggtctcc gacggccgcc
    20581 acgtcttcgt cgccccccgg gccacgcacc tcatcgacca actcaccgcc cgcggatatg
    20641 tccccgtccc cgtcgacctc tccgagttcc acaaggccgg cggcggcatc aagtgctgca
    20701 cccaggagct tcgcccatga cgactgcgcc caccaaaacc cgccgctcct ccgcctccct
    20761 catcgaggcc gaggccccgg tcctggccca caactaccac cccctccccg tggtcatctc
    20821 ccgcgccgag ggcgtctggg tcgaggacgt cgagggccgc cgctacctcg acatgctggc
    20881 cggctactcg gcgctcaatt tcggccaccg ccacccggcc ctcatcgagg cggcccaccg
    20941 ccagctggac gccctcaccc tcacctcccg cgccttccac cacgaccgcc tcgggcagtt
    21001 cgccggcgcg ctggccgagc tcaccggcct ggacatggtc ctccccatga acaccggcgc
    21061 cgaggccgtc gagagcggca tcaagctcgc ccgcaaatgg gcctacgagg tcaagggcgt
    21121 ccccgccgac caggccacca tcgtcgtcgc cggcggcaac ttccacggcc gcaccacgac
    21181 catcatcagc ttctccgacg acgacgaggc ccgcgccaac ttcggcccct acacccccgg
    21241 cttccgcacc gtcccctaca acgacctggc cgccctcgaa gccgccatcg acgacaccac
    21301 cgccgccgtc ctgatcgagc ccatccaggg cgaggccggc gtcatcatcc ccgacgacgg
    21361 ctacctcgcc ggcgtccgcg ccgcgaccag ccgcgcgaac tgcctcttca tcgccgacga
    21421 gatccagtcc ggcctcggcc gcaccggcac caccctcgcc gtcgaacacg aacaggtcgt
    21481 ccccgacgtc atcctcctcg gcaaggccct cggcggcggc atcgtccccg tctccgccgt
    21541 cgtcgcccgc cgcgaggtca tgtccgtcct cggcccgggc caacacggct ccaccttcgg
    21601 cggcaaccca ctcgccgccg ccgtcggcac ggccgtcgtc gacctcctga ccaccggcga
    21661 attccaatcc cacgccgccg acctgggcaa ggtcctgcac tccggcctca ccgacctcct
    21721 cggcaagggc gtcaccgcct tccgcgcccg cggcctgtgg gccggcgtcg acatcgaccc
    21781 cgccctgggc accggccgca ccatcagcga acgcctcatg tccgagggcg tgctggtcaa
    21841 ggacacccac ggctcaacta tccgcctggc cccgcccctg accatcaccg agcacgaact
    21901 gaccacggcg atcgccgcgt tgggccgcgt actcgcctaa cgcccgccga acgcctcgcc
    21961 cttcaccgcg gcgacgaacg cgctccaagc ccccgccggt acgacgatcg ccggcccgtg
    22021 cggggccttg gagtctcgga cgggtatgcc gtgggggtga ccgtcgatca cctcgacaca
    22081 gtcagctccc tcgttgtcgc tgtacgacga cttacgccag ccgttcagcg tggcagcgct
    22141 cggaatggtg ccttcagcca tgatgtccat actccttcgc ttgcgcccgc atcagggaca
    22201 gtgactgctg cagcggcagt gcg
//
