LOCUS       NZ_LJSN01000003        20720 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces noursei strain JCM 4701 scaffold3, whole genome shotgun
            sequence.
ACCESSION   NZ_LJSN01000003
VERSION     NZ_LJSN01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
REFERENCE   2  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method :: SPAdes v. 3.6; SMRT Analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891315.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 20:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,947
            CDSs (total)                      :: 8,851
            Genes (coding)                    :: 8,489
            CDSs (with protein)               :: 8,489
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 362
            CDSs (without protein)            :: 362
            Pseudo Genes (ambiguous residues) :: 0 of 362
            Pseudo Genes (frameshifted)       :: 118 of 362
            Pseudo Genes (incomplete)         :: 301 of 362
            Pseudo Genes (internal stop)      :: 23 of 362
            Pseudo Genes (multiple problems)  :: 74 of 362
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2993416
            Orig. end                         :: 3014136
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJSN01000003.1.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20720
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="18"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20720
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20720
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10720](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10720)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(724..2940)
                     /gene="ligA"
                     /locus_tag="AOB60_RS34480"
                     /old_locus_tag="AOB60_33320"
     CDS             complement(724..2940)
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602953.1"
                     /locus_tag="AOB60_RS34480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33320"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_102926014.1"
                     /transl_table=11
                     /translation="MAGEQHAVASKVPAAAREKHAQLAEQIEEHRFRYYVKDAPVVSDA
                     EFDKLLRALEALEETHPELRTPDSPTQKVAGSYATEFTEVAHRERMLSLDNAFDDEELS
                     AWAERIATELGGDARGAGYHFLCELKVDGLAVNLTYEHGRLTRAATRGDGRTGEDITPN
                     VRTIAEIPHRLQGDRVPELVEIRGEVYFPMEKFLELNERLVADGKPPFANPRNAAAGSL
                     RQKDPKVTATRPLHMVVHGLGARDGLEIDRLSEAYDLLKEWGLPTATHNRVVDSLAAVR
                     EFIAHYGDPETRRTAVEHEIDGVVVKLDEIRLQGRLGATSRAPRWAIAWKYPPEEVNTK
                     LVDIRVGVGRTGRVTPYAVVEPVTVAGSEVEFATLHNQDVVKAKGVLIGDTIVIRKAGD
                     VIPEILGPVVDLRDGTEREFVMPAECPECGSALQPAKEGDIDLRCPNARSCPAQIRERL
                     FYLAGRKCLDIENFGYVAATALSQPLEPAEPPLTDEGGLFDLSVEELLPIKSHVLDPDT
                     GLPKRDPKTGEEKVVTFFANQKGEPKKNTLAMLENIQAAKERPLARILTGLSIRHVGPV
                     AAQALAREFRSIDRIREASEEELAAVEGVGGTIAASLKQWFAVDWHQEIIERWRAAGVR
                     MEEEQSGETGPRPLEGVTVVVTGTLQSHTRDGAKDALQALGAKVTGSVSKKTGFVVVGD
                     NPGSKYDKAMQLKVPVLDDDGFAVLLEQGPEAARAVAVTPPEEE"
     gene            complement(2971..3984)
                     /locus_tag="AOB60_RS34485"
                     /old_locus_tag="AOB60_33325"
     CDS             complement(2971..3984)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018087257.1"
                     /locus_tag="AOB60_RS34485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33325"
                     /product="methionine synthase"
                     /protein_id="WP_073443721.1"
                     /transl_table=11
                     /translation="MSENTRHKWAAGAATGIGSMPGGDAREAAKTVTGSLEDFPHLPEL
                     PARGPGADMIGRTLGLLVELYAHVEPSGWRISDRPGRDTRRARSWLGEDLDALEEFTQG
                     YEGPLKVSAVGPWTLAAALELRNGEAALGDPGACRDLTESLAEGLRGHLAEVRRRVPGA
                     ELVLQLDEPSLTAVLQGRVRTASGYRTHRAVDRAVVEGALRDLVGAADGAPVVVHSCAP
                     EVPFALLRRAGATGISFDAALLTEREDEVLGEAVEGGTALFAGVVPGVDGRLSDPAGSV
                     MGVRTLWRRLGLAPGLLAESVVVTPSCGLAGASPAYARAALAHCVRAARSLADNPE"
     gene            complement(4075..5475)
                     /locus_tag="AOB60_RS34490"
                     /old_locus_tag="AOB60_33330"
     CDS             complement(4075..5475)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571832.1"
                     /locus_tag="AOB60_RS34490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33330"
                     /product="MFS transporter"
                     /protein_id="WP_102926015.1"
                     /transl_table=11
                     /translation="MITENAAPRATASTPTRPAPAGGAAQLVVLALGFVMASLDTGIMN
                     VAAHDLQARLGLTMSGLTWVVDGYVLAFAALLLLAGSLAKRFGARRIYLVGLAVFTAAS
                     LLGAAAPGGGALVAARFAQGAGAALFMPSSLSLLMNAFPEPARRAKVLGIWTAIVSTSV
                     ALAPTVGGLLVGTLGWRSIFLVNLPIGIAGLLLTRRVIAAVPGTGAPLSGTGHVLGLLA
                     LGSLSYALIEGPAAGWAAPGVLAAFVVTVLAAAGFVVRERTARTPVLPVTLFADSRFSA
                     ANAVGFLFNFAFYGALFVLGLFLQTGRGADAVTAGLQMLPAVLVIPIGNVLYTRIAPRT
                     GNRAALAVPLALSAAGYLLLFLILSPTLPYGVIAVVLAVTNIGSGISSPAMTGVLMEAA
                     GREHADIGSATLNANRQVGSLVGIAGMGAILTGAGDAYQGTGYAFALTAVALVAAAVVG
                     WLGVRGRR"
     misc_feature    complement(5514..5529)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     gene            complement(5609..6073)
                     /locus_tag="AOB60_RS34495"
                     /old_locus_tag="AOB60_33335"
     CDS             complement(5609..6073)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571833.1"
                     /locus_tag="AOB60_RS34495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33335"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_258018238.1"
                     /transl_table=11
                     /translation="MTTSRATTEAKTTAAAGCGFREIRGLVTELSRRLDAHQRSRIAEL
                     DLTPTQAKALEELGEPKTARELAAVLCCEPPNVTYVISKLEKQGMVVRRPHPADGRAKQ
                     LVLTEAGRELRLDLLRRMGTESPLDHLSHEQRSALRDELLRALGRATDAA"
     gene            complement(6175..6864)
                     /locus_tag="AOB60_RS34500"
                     /old_locus_tag="AOB60_33340"
     CDS             complement(6175..6864)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (1-172). E-value: 2.7e-12. Score:
                     38.9. Matches aSDomain:
                     nrpspksdomains_AOB60_RS34500_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602956.1"
                     /locus_tag="AOB60_RS34500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33340"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_039632571.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-29, bitscore:
                     101.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTHLITGAGSGIGAAVARRLAERGEELWLLARDVGRAKELAERF
                     PGAHTLVGDLATPEKLDWALGHQRLPERLDSIQHIAGVIELGAVGDLPAKAWQRQLAVN
                     LVAPAEITRLLLPLVRIAKGDVVFVNSGAGLTANPNWGGYAASKHGLKALADALRAEEH
                     DNGVRVTSIYPGRTATPMQESTHRQEGKAYDASRWIDPESVATAILTAIDLPRDAEIKD
                     LVVRPGR"
     aSDomain        complement(6349..6861)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOB60_RS34500_PKS_KR.1"
                     /evalue="2.70E-12"
                     /label="AOB60_RS34500_PKS_KR.1"
                     /locus_tag="AOB60_RS34500"
                     /protein_end="172"
                     /protein_start="1"
                     /score="38.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="GTHLITGAGSGIGAAVARRLAERGEELWLLARDVGRAKELAERFP
                     GAHTLVGDLATPEKLDWALGHQRLPERLDSIQHIAGVIELGAVGDLPAKAWQRQLAVNL
                     VAPAEITRLLLPLVRIAKGDVVFVNSGAGLTANPNWGGYAASKHGLKALADALRAEEHD
                     NGVRVTSI"
     CDS_motif       complement(6790..6858)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOB60_RS34500_0001"
                     /evalue="2.40E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AOB60_RS34500"
                     /protein_end="25"
                     /protein_start="2"
                     /score="23.4"
                     /tool="antismash"
                     /translation="THLITGAGSGIGAAVARRLAERG"
     gene            complement(6899..7441)
                     /locus_tag="AOB60_RS34505"
                     /old_locus_tag="AOB60_33345"
     CDS             complement(6899..7441)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lysine_decarbox"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539206.1"
                     /locus_tag="AOB60_RS34505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33345"
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="WP_073443356.1"
                     /sec_met_domain="Lysine_decarbox (E-value: 1.4e-34,
                     bitscore: 116.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNICVFCSAADLDDRYVVPAREFAESIGRRGHALVWGGSDTGLMK
                     VMADGVQEAGGKLLGVSVEFLADKTRANADEMVVTKDLAERKAQLLARADAIVVMVGGT
                     GTLDEATEILELRKHGMHSKPVVLLNTAGFYDGLKAQFERMEAEGFLPVPLSELVIFAE
                     DGAGALAHLEAWAAAAG"
     gene            complement(7543..8919)
                     /gene="gdhA"
                     /locus_tag="AOB60_RS34510"
                     /old_locus_tag="AOB60_33350"
     CDS             complement(7543..8919)
                     /EC_number="1.4.1.4"
                     /GO_function="GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539207.1"
                     /locus_tag="AOB60_RS34510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33350"
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="WP_073443358.1"
                     /transl_table=11
                     /translation="MSTVHTGVTQSGLTAELASLHAELVRRNPGEAEFHQAALEVLETL
                     APVLTARPEFADAKVLERMVEPERQIMFRVPWQDDSGKIRVNRGFRVEFNSALGPYKGG
                     LRFHASVNLGIVKFLGFEQIFKNALTGLNIGGGKGGSDFDPHGRSDAEVMRFCQSFMTE
                     LHRHLGEHTDVPAGDIGVGGREIGYLFGQYRRITNRWEAGVLTGKGLAWGGSKARTEAT
                     GYGNVLFTEEMLKQRGEELDGQQVVVSGSGNVAIYTIEKAQALGANVLTVSDSGGYVVD
                     EKGIDLALLKQIKEVERGRVGDYAQRRGSSAKYVAGGRVWDVACDVALPSATQNELDAD
                     AARILVRNGVKAVSEGANMPTTPEAVALLKEAGVAFGPGKAANAGGVATSALEMRQNSA
                     REAWSFERAEGELAAIMRGIHDTCYQTAERFGRPGDYVAGANIAGFERVADAMLDQGLI
                     "
     gene            complement(9107..9835)
                     /locus_tag="AOB60_RS34515"
                     /old_locus_tag="AOB60_33355"
     CDS             complement(9107..9835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602959.1"
                     /locus_tag="AOB60_RS34515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33355"
                     /product="VC0807 family protein"
                     /protein_id="WP_102926016.1"
                     /transl_table=11
                     /translation="MTQAATVTATTSQGRALLQSLTPLLVDAAIPLGSYFLLAEGFGMS
                     TVAALAWSSVVPALRTIWGLVRERTVNGLALLILVVNVVGLATSTLTGDARLMMAKDSG
                     VSSVVGIAILLSVRGRRPLMTAGLRPWVTKGGPEGNAAWDRLWARSARFRQLERRFSTV
                     WGSALLIECVVKVVGAYALPVHIMVWLGTVLTVVAILLAMVVAGGSCAEPMEQMVKAEV
                     RAAGEPAAAGNAEPAPAAAA"
     gene            complement(10001..10720)
                     /locus_tag="AOB60_RS34520"
                     /old_locus_tag="AOB60_33360"
     CDS             complement(10001..10720)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04539.1"
                     /locus_tag="AOB60_RS34520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33360"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_079181756.1"
                     /sec_met_domain="CDPS (E-value: 1.4e-66, bitscore: 221.9,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAGLVSAPDHGMREEILGDRSRMIRQRGEHALIGISAGNSYFSQ
                     KNTIMLLQWAGQRFERTDVVYVDTHIDEMLIAEGRSAQEAERSVKRTLKDLRRRLRRSL
                     ESVGDHAERFRVRSLSELQETPEYRAVRERTDRAFEEDAEFATACEDMVRAVVMNRPGD
                     SVGLSAEHLRAGLNYVLAEAPLFADSPGVFSVPSSVLCYHIDTPITAFLSRRETGFRAA
                     EGQAYVVVRPQELADAA"
     misc_feature    complement(10706..10708)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10757..11074)
                     /gene="albB"
                     /locus_tag="AOB60_RS34525"
                     /old_locus_tag="AOB60_33365"
     CDS             complement(10757..11074)
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_039632579.1"
                     /locus_tag="AOB60_RS34525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33365"
                     /product="albonoursin biosynthesis protein AlbB"
                     /protein_id="WP_039632579.1"
                     /transl_table=11
                     /translation="MNPGETVLPPQLREEIALLAVYLLSSGRGLLEEPADYGIYRCTDG
                     ARRALQLLDEHGGSTARLTAVRERLDEVMFAPMGEDRDMGAILDDLCRQMADALPEIET
                     P"
     gene            complement(11034..11624)
                     /locus_tag="AOB60_RS34530"
                     /old_locus_tag="AOB60_33370"
     CDS             complement(11034..11624)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572569.1"
                     /locus_tag="AOB60_RS34530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33370"
                     /product="nitroreductase family protein"
                     /protein_id="WP_102926017.1"
                     /sec_met_domain="PF00881 (E-value: 2.5e-13, bitscore: 48.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAHSSSESPPESLPDAWTVLKTRTAVRDYAKEPVDDALIEQLLE
                     AMLAAPTASNRQAWSFMVVRRPAAVRRLRAYSPGVLGTPAFFVVACVDRSLTDNLSPKL
                     SQKIYDTSKLCVAMAVENLLLAAHAAGLGGCPVGSFRSEIVKSMLGIPEHIEPMLVVPI
                     GRPATALVPSQRRAKNEVVNYESWGNRAAAPTA"
     misc_feature    complement(11828..11842)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
     misc_feature    11835..11849
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.91"
                     /tool="antismash"
     misc_feature    11842..11856
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
     misc_feature    complement(11893..11913)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     gene            complement(12175..13302)
                     /gene="mnmA"
                     /locus_tag="AOB60_RS34535"
                     /old_locus_tag="AOB60_33375"
     CDS             complement(12175..13302)
                     /EC_number="2.8.1.13"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016783 - sulfurtransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="mnmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311592.1"
                     /locus_tag="AOB60_RS34535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33375"
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="WP_073443365.1"
                     /transl_table=11
                     /translation="MTDAAAPRRLRVLAAMSGGVDSAVAAARAAEAGHDVTGVHLALSE
                     NPTSFRTGARGCCTIEDSHDARRAADVIGIPFYVWDLAERFREDVVEDFIAEYEAGRTP
                     NPCLRCNEKIKFAALLDKALALGFDAVCTGHYAQVILREDGSRELHRATDMAKDQSYVL
                     GVLDDRQLAHAMFPLGDTPTTKTEIREEAARRGLFVAKKPDSHDICFIADGDTQGFLAK
                     RLGSAEGDIVDESGTKLGTHEGAYGFTIGQRKGLRIGTPAADGKPRYVLDISPVNNTVT
                     VGPVESLDVTALTAIKPRWCGRPPADGPAVYTAQLRAHGGETEVTAEVVGEELRVSFTE
                     PVRGVAPGQAVVLYDGTRVVGSATIATTRRAASVA"
     gene            13510..14154
                     /locus_tag="AOB60_RS34545"
                     /old_locus_tag="AOB60_33380"
     CDS             13510..14154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891305.1"
                     /locus_tag="AOB60_RS34545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33380"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_102926441.1"
                     /transl_table=11
                     /translation="MLLLGGGAAVAAGAAAVAAREELAYWWGQLPGNSRPRKEGEVDFA
                     GAQWSAASPANYRQANRPDDYTVDRVVIHVVQGSFATALKVFRDPFHEASAHYVVRGDG
                     HIAQTVRELDVAFHAGNRGYNERSVGIEHAGFVDRPESFTPDMYAASARLTAGICRRYD
                     FPADREHVVGHIEVPGTDHTDPGSHWDWDRYLTLVRAELRRPAARTRPGTT"
     gene            complement(14151..15320)
                     /locus_tag="AOB60_RS34550"
                     /old_locus_tag="AOB60_33385"
     CDS             complement(14151..15320)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (1-372). E-value: 3e-71.
                     Score: 232.2. Matches aSDomain:
                     nrpspksdomains_AOB60_RS34550_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966104.1"
                     /locus_tag="AOB60_RS34550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33385"
                     /product="cysteine desulfurase family protein"
                     /protein_id="WP_073443366.1"
                     /sec_met_domain="Aminotran_5 (E-value: 7.4e-66, bitscore:
                     220.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVYLDHAATTPMLPEAVQAMTAQLTVTGNASSLHAAGRRARRTVE
                     EARESLAASLGARPSEVVFTAGGTEADNLAVKGLYWSRRAADPARTRILVSPVEHHAVL
                     DAVEWLAEQEGATVDWLPVDHYGRVHAEALREAIARNPADVALATVMWANNEIGTVQPI
                     RELAEVAREFAIPLHADAVQAVGQLDVDFAASGLAAMTVSGHKIGGPYGIGALLLGREH
                     APVPVLHGGGQERHVRSGTLDTPAIAAFAAAGRHAVAHREEFARDIGALRDDLIKAVQA
                     AAPDAVLGGDPDPAGRLPANAHFTFPGCEGDSLLLLLDAQGIACSTGSACTAGVAQPSH
                     VLLATGMSQDLARGTLRFSLGHTSTAKDVAALAEVIGPVVERARGAGLS"
     aSDomain        complement(14205..15317)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOB60_RS34550_Aminotran_5.1"
                     /evalue="3.00E-71"
                     /label="AOB60_RS34550_Aminotran_5.1"
                     /locus_tag="AOB60_RS34550"
                     /protein_end="372"
                     /protein_start="1"
                     /score="232.2"
                     /tool="antismash"
                     /translation="VYLDHAATTPMLPEAVQAMTAQLTVTGNASSLHAAGRRARRTVEE
                     ARESLAASLGARPSEVVFTAGGTEADNLAVKGLYWSRRAADPARTRILVSPVEHHAVLD
                     AVEWLAEQEGATVDWLPVDHYGRVHAEALREAIARNPADVALATVMWANNEIGTVQPIR
                     ELAEVAREFAIPLHADAVQAVGQLDVDFAASGLAAMTVSGHKIGGPYGIGALLLGREHA
                     PVPVLHGGGQERHVRSGTLDTPAIAAFAAAGRHAVAHREEFARDIGALRDDLIKAVQAA
                     APDAVLGGDPDPAGRLPANAHFTFPGCEGDSLLLLLDAQGIACSTGSACTAGVAQPSHV
                     LLATGMSQDLARGTLRFSLGHTSTAKDVAAL"
     gene            complement(15526..16404)
                     /locus_tag="AOB60_RS34555"
                     /old_locus_tag="AOB60_33390"
     CDS             complement(15526..16404)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571841.1"
                     /locus_tag="AOB60_RS34555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33390"
                     /product="thioesterase family protein"
                     /protein_id="WP_102926018.1"
                     /transl_table=11
                     /translation="MASVTVGNSEFDRDTAVTRSAPGVYDAHLSEGWTIINAVNGGYLL
                     ALMGRALGDALPHPDPLTVTAHYLTASVPGPAVVRTEVIRTGRTLSTGAATLVQFADDG
                     SEVERMRVLATYGDLAALPDDVRTTAKPPAIPPYEHCLGTSPTPERGGGTPMAPDGRPA
                     IPGSTAIAGRLDLRLDPATVGWAVGAPSGKGEMRGWFGLADGRDPDPLSLLLTVDALPP
                     TAFELGLRGWVPTVELTCHVRHRPAPGPLRVAITTRNLAGGFLEEDAEVWDSEDRLVAQ
                     SRQLARTILVQ"
     gene            16521..17153
                     /locus_tag="AOB60_RS34560"
                     /old_locus_tag="AOB60_33395"
     CDS             16521..17153
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602976.1"
                     /locus_tag="AOB60_RS34560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33395"
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="WP_039632589.1"
                     /transl_table=11
                     /translation="MLHVLYLIGVAAFAASGVLAAYRANMDPFGGLVLAFAASISGGTL
                     RDLILDRRPLYWTHDWVLLTVIICVGVGTIVYLRFWSLPRKSLLVVDAIGLSVVTVIGA
                     RAAISAGATPLAVIILAVLTGVAGEVIRDVLCGEFPPLLLREDVYAIAALAGACCYLLM
                     DRLGAGANPAAVVSAGLVFALRMGALYLGLHLPRPQQLRGRGREDAG"
     gene            complement(17158..18567)
                     /locus_tag="AOB60_RS34565"
                     /old_locus_tag="AOB60_33400"
     CDS             complement(17158..18567)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539214.1"
                     /locus_tag="AOB60_RS34565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33400"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_102926019.1"
                     /transl_table=11
                     /translation="MALSRSARRSSRWLALATAVASAATIAAAPAATPGAPGIGDPYFP
                     GLGNGGYRPLHYDLGVSYHPDSGRLDGRTTLTARATQDLSSFDLDLQKLTVDQVRVDGR
                     PARFSRTGDELVIRPGRPLARGERFAVTVVYHGVPQPLSGPIVFGSQYGWMKTKDGVFV
                     ACEPNAASTWFPSSDHPDEKATYDIRIDAPKGLTGVSNGRLVGSGEHGDRAWFHWRESR
                     PMAPYLATATIGKFDVRTGTTPGGTPIYVATDPTLPTGKVDVYGVTAAATDYWSKVFGP
                     YPFEETGAIVDDMPQAGFSLEVQSKPAYSAVRNESTIVHELAHQWFGDSVSVRQWKDIW
                     LNEGFATYAQWLWAEHKGTATAHDAFRKAYQGIPADDAFWKIKVSDPQRDTMFSDAVYE
                     RGAMTLQALRERIGDRAFFRLLPAWTARHRYGNADTADFIALAEKISGQRLGDLFHTWL
                     DTQSRPVLSER"
     gene            complement(18667..19692)
                     /locus_tag="AOB60_RS34570"
                     /old_locus_tag="AOB60_33405"
     CDS             complement(18667..19692)
                     /EC_number="7.4.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571844.1"
                     /locus_tag="AOB60_RS34570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_33405"
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="WP_258018350.1"
                     /transl_table=11
                     /translation="MLRVRGLVRHFPITKGLLKRKVGAVQAVDGIDFDVFPGETLGVVG
                     ESGCGKSTMGRLITRLDEPTGGSVEFEGQDITHLSPGRLRPLRRDIQMIFQDPYGSLNP
                     RHTIGGIVSTPFRLQGVEPEGGVKKEVQRLLELVGLSPEHYNRYPHEFSGGQRQRIGIA
                     RALALKPKLVVADEPVSALDVSIQAQVVNLMDDLQEELGLTYVIIAHDLSVIRHVSDRI
                     AVMYLGKIVELADRDSLYASPRHPYTKALLSAVPVPDPKRRTQRGRILLKGDVPSPINP
                     PSGCRFRTRCWKVTEECITTEPPLIQLRTGHQVACHHPEDESDNSVEATESSDGKASTG
                     Q"
ORIGIN
        1 gccgccgagc ggcagccgac tgcaccacag cagcccccgg ctgacgagga gatagctccc
       61 cgccatcacg aggacctcgg gcaggacgga gaggtcccag gcatcgggcg cccagggccg
      121 gcggacgctg ggctgcaccc cgcagacgac caggccgagc gccgcggcgc cgatgccgag
      181 gaggtcaact gccccgtgga ccacggcctg tcgccagcgc tgccggcggg cggcgccgac
      241 caggaccacg acggagaggc tgaccaggat ggccggcacc cagccgtaga gcaggagcac
      301 ggcgagggcg agggccgccc cggaaccagt gccgccccac caccggtccc ggccgagggc
      361 gaccagatgg ccgacgatga cgccggtcag gaccgccagc gaccagccga tggctccggc
      421 ggggaacaac ggctcgccgt cgccgagcga gtggagcaca ccggcggcga gcaccacgcc
      481 cgccgccatg acgatggccg cgggcaacgc gggcaccaca agccggcgga gccgcgacgc
      541 cggagcggcg ctgtcggtcg gtttcattcc gatccctctc acagccggct gtgcccgcgc
      601 cacggcaggc gcacacgtca acagtaggac gcggaaggcc gctgcgggca gcgatccgca
      661 gcggttgccc gaatgcgacc cggcctccca gatcaatctg gtatgcgccg atggggtgac
      721 acctcactcc tcctcaggcg gagtgacagc taccgctcgt gccgcctcgg gaccctgctc
      781 cagcagcaca gcgaagccgt catcgtccaa cacggggacc ttcaactgca tggctttgtc
      841 gtacttcgaa ccggggttgt cgcccaccac tacgaatccg gtcttcttgg aaacggatcc
      901 ggtcaccttc gcaccaagag cctgtagcgc atctttcgcg ccatctctgg tgtgtgactg
      961 aagtgtgccc gttaccacga cggtgacgcc ttccagggga cgcgggcccg tttcacccga
     1021 ctgctcctcc tccatacgga cgcccgcggc ccgccagcgc tcgatgatct cctggtgcca
     1081 gtccacggcg aaccactgct tgagcgaggc ggcgatggtg ccgccgacgc cctccacggc
     1141 cgccagttcc tcctcgctcg cctcccggat ccggtcgatc gagcggaact cccgggccag
     1201 cgcctgcgcc gccaccgggc ccacgtgacg gatcgacagc ccggtgagga tccgggccag
     1261 cgggcgctcc ttggccgcct ggatgttctc caacatggcc agggtgttct tcttcggctc
     1321 gcccttctgg ttggcgaaga aggtgacgac cttctcctcg ccggtcttcg ggtcgcgctt
     1381 gggcaggccg gtgtccgggt cgaggacatg ggacttgatg ggcagcagct cctcgaccga
     1441 gaggtcgaac aggccgccct cgtccgtcag cggcggctcg gcgggctcca gcggctgact
     1501 gagggcggtg gcggcgacat agccgaagtt ctcgatgtcc aggcacttgc ggccggcgag
     1561 gtagaacagc cgctcgcgga tctgggcggg gcaggaccgg gcgttggggc accgcaggtc
     1621 gatgtcgccc tccttggcgg gctggagcgc cgagccgcac tcgggacact cggcgggcat
     1681 cacgaactcc cgctcggtgc cgtcccgcag atcgacgacc gggccgagaa tctccggaat
     1741 gacgtcgccc gccttgcgga tgacgatggt gtcgccgatc aggacgccct tggccttaac
     1801 cacgtcctgg ttgtgcaggg tggcgaactc cacctcggaa ccggcgacgg tgaccggctc
     1861 gacgaccgcg tacggcgtga cccgtccggt gcggccgacg ccgacgcgga tgtccaccag
     1921 cttggtgttg acctcctccg gcgggtactt ccaggcgatc gcccagcgcg gcgcccgcga
     1981 ggtggcaccc agccggccct ggagccggat ctcgtcgagc ttgaccacga cgccgtcgat
     2041 ctcgtgctcg acggccgtgc ggcgggtctc ggggtcgccg tagtgggcga tgaactcccg
     2101 taccgcggcg agggagtcca ccacgcggtt gtgcgtggca gtgggcaggc cccactcctt
     2161 gagcaggtcg tacgcctcgg agaggcggtc gatctccagg ccgtcgcggg cgccgaggcc
     2221 gtgcaccacc atgtgcagcg ggcgggtggc ggtgaccttg gggtccttct ggcgcagcga
     2281 accggccgcg gcgttacggg ggttggcgaa cggcggcttg ccgtcggcca ccaggcgctc
     2341 gttgagctcc aggaacttct ccatcgggaa gtagacctcc ccgcggatct cgaccagctc
     2401 ggggacccgg tcgccctgga ggcggtgcgg gatctcggcg atggtgcgga cgttgggcgt
     2461 gatgtcctcg ccggtgcggc cgtcgccccg ggtggcggcg cgggtgaggc ggccgtgctc
     2521 gtaggtgagg ttgaccgcga ggccgtcgac cttcagctcg cacaggaagt ggtagccggc
     2581 gcccctggcg tcgccgccca gttcggtggc gatccgctcg gcccaggccg acagctcctc
     2641 gtcgtcgaag gcgttgtcca acgagagcat ccgctcgcgg tgcgcgacct cggtgaactc
     2701 cgtggcgtac gacccggcga ccttctgggt cggggagtcc ggggtgcgca gctcgggatg
     2761 ggtctcctcc agggcctcca gggcgcgcag cagcttgtcg aactccgcgt cgctgacgac
     2821 cggggcgtcc ttcacgtagt accggaagcg gtgctcctcg atctgctcag cgagctgcgc
     2881 gtgcttctcc cgtgccgcgg cgggcacctt ggatgccacc gcgtgctgtt cgccagccac
     2941 cgtcttgtcc tcccgtgtcc ttgagggcgg tcactcaggg ttgtctgcga gtgacctcgc
     3001 cgcccggacg cagtgggcga gcgccgcgcg ggcgtaggcg ggcgaggcgc ccgccagacc
     3061 gcacgacggg gtgaccacca cggactccgc gagaagtccc ggtgccagcc ccagcctgcg
     3121 ccacagcgtc cggacaccca tgacgctacc ggcagggtct gacaatcgac cgtccacgcc
     3181 cggcaccacg cccgcgaaca gcgcggtacc gccctccacc gcctcgccga gcacctcgtc
     3241 ctcacgctcg gtgagcagcg cggcatcgaa cgagatgccg gtcgcgccgg cccgccgcag
     3301 cagtgcgaac ggcacctcgg gcgcgcagga atggaccacg accggtgcgc cgtccgcggc
     3361 cccgaccagg tcgcgcagcg cgccctcgac gaccgcgcgg tccacggccc gatgggtgcg
     3421 gtagccgctc gcggtcctca cccgcccctg gagcaccgcg gtcagcgacg gctcgtcgag
     3481 ctggaggacg agttcggcgc ccggcacccg ccgtcggacc tcggcgagat gaccgcgcag
     3541 tccctcggcg agcgactcgg tgaggtcccg gcaggccccg gggtcgccga gcgccgcctc
     3601 gccgttgcgc agctccaggg cggcagccag ggtccacggg ccgaccgcgg agaccttcag
     3661 cggtccctcg tatccctggg tgaactcctc cagggcgtcg aggtcctcgc cgagccagga
     3721 gcgggcccgg cgggtgtcgc ggccgggccg gtcgctgatc cgccagccgc tgggctccac
     3781 atgggcgtag agctcgacga gcaggcccag ggtgcggccg atcatgtcgg cgccgggccc
     3841 ccgggccggg agctcgggca gatgggggaa gtcctccagc gatccggtga cggtcttcgc
     3901 cgcttcgcgt gcgtcgccgc ccggcatcga tccgatgccg gtcgccgcgc ccgcggccca
     3961 cttgtgcctg gtgttctcgc tcaccccgga agggtatgcg gcggtgggcc gggcgggccg
     4021 ccccagcccc gcccggccca ccgccgtacg cccggcgcga acgccgcgcc cgggtcagcg
     4081 ccggccgcgg acgcccagcc agccgaccac cgccgcggcc accagggcca ccgcggtcag
     4141 cgcgaaggcg tatccggtgc cctggtaggc gtcgcccgcg ccggtcagga tcgcgcccat
     4201 gccggcgatg ccgaccagcg agccgacctg gcggttggcg ttgagggtcg cgctgccgat
     4261 gtcggcgtgc tcgcggccag cggcctccat caggacgccg gtcatcgccg gggagctgat
     4321 cccgctgccg atgttggtga cggccagcac caccgcgatc accccgtacg gcagggtcgg
     4381 cgagaggatc aggaagagca ggaggtagcc ggcggcggag agggccaggg ggacggcgag
     4441 cgcggcccgg ttgccggtgc gcggcgcgat ccgcgtgtag agcacgttgc cgatcgggat
     4501 gacgaggacg gccgggagca tctgcagacc cgcggtcacc gcgtcggcgc cgcggcccgt
     4561 ctggaggaag agcccgagga cgaacagcgc cccgtagaag gcgaagttga agaggaagcc
     4621 gaccgcgttg gcggcggaga agcggctgtc ggcgaagagg gtgacgggca ggaccggggt
     4681 gcgggcggtg cgttcccgga ccacgaagcc ggcggcggcg agcacggtca ccacgaacgc
     4741 cgccaggacg ccgggggcgg cccagccggc ggcgggcccc tcgatgaggg cgtagctgag
     4801 tgagccgagg gcgagcaggc caaggacgtg gccggtgccg ctgagcgggg cgccggtgcc
     4861 cgggactgcg gcgatcaccc ggcgggtgag cagcagtccg gcgatcccga tggggaggtt
     4921 gaccaggaag atgctgcgcc agccgagggt gccgacgagc aggccaccga cggtcggtgc
     4981 cagggcgacg gaggtggaga cgatcgcggt ccagatgccg agcaccttcg cccggcgggc
     5041 cggctccggg aaggcgttca tcagcagcga cagcgagctg ggcatgaaga gcgcggcgcc
     5101 cgccccttgg gcgaagcggg ccgccaccag ggcgccgccg cccggcgccg cggcgcccag
     5161 cagggacgcg gcggtgaaga cggccagccc gacgaggtag atccgccggg cgccgaaccg
     5221 cttggcgagc gagccggcga gcagcagcag cgcggcgaag gcgaggacgt agccgtcgac
     5281 gacccaggtg aggccggaca tggtcagccc gagccgggcc tggaggtcgt gcgcggcgac
     5341 gttcatgatg ccggtgtcca ggctcgccat cacgaacccc agggccagga cgacgagttg
     5401 ggcggctccg ccagcgggtg cgggacgggt gggggtgctc gccgtcgcgc gcggcgccgc
     5461 gttctcagtg atcatggatt tagttatagc tgtatccatc catcgcgcgc gatggttaca
     5521 gctataactt tatcgaagtg ataccaagaa acgccgaagg cccccgggac gatgccccgg
     5581 gggccttcgg caggacggcg gacgcgctct aggccgcgtc cgtagcgcgg cccagcgctc
     5641 tgaggagttc gtcgcggagc gcgctgcgct gctcgtggga gaggtggtcc agcggggact
     5701 ctgtgcccat ccgccgcagc aggtccagcc gcagctcccg accggcctcg gtcagcacca
     5761 gctgcttggc gcgcccgtcc gccgggtgcg ggcggcggac caccatcccc tgcttctcca
     5821 gcttggagat gacataggtg acgttcggcg gctcgcagca cagcaccgcg gccaactccc
     5881 gcgcggtctt gggctcgccc agctcctcca gcgccttcgc ctgcgtcggc gtcaggtcca
     5941 gctccgcgat ccggctgcgc tggtgggcgt ccaggcggcg gctcagctcg gtgaccagcc
     6001 ccctgatctc ccggaacccg caccccgccg cggcggtggt cttcgcttcg gtggtcgccc
     6061 ttgacgtggt cacccctgaa gcgtacgtcg cccccgcgcg aggcacgggg gccaggtccg
     6121 gtcggggcgg gcggaccgcc gggtggcccc gggagccccg gggccacccg gtggtcagcg
     6181 gcccggccgg accaccaggt ccttgatctc cgcgtcccgc ggcaggtcga tcgcggtgag
     6241 gatggccgtg gccaccgact ccgggtcgat ccaccgggac gcgtcgtacg ccttgccctc
     6301 ctggcggtgg gtgctctcct gcatgggcgt ggcggtgcgc cccgggtaga tcgaggtgac
     6361 ccggacgccg ttgtcgtgct cctccgcgcg cagcgcgtcg gccagcgcct tcaggccgtg
     6421 cttgctcgcg gcgtacccgc cccagttggg gttcgcggtg agcccggcac cggagttgac
     6481 gaagaccaca tcgcccttgg cgatccggac cagcggcagc agcagccggg tgatctcggc
     6541 gggcgcgacg aggttgaccg ccagctgccg ctgccacgcc ttggccggca ggtcgccgac
     6601 cgcacccagc tcgatgacgc ccgcgatgtg ctggatcgag tcgagccgct ccggcagccg
     6661 ttggtgcccg agcgcccagt caagcttctc gggggtggcg aggtcaccga cgagggtgtg
     6721 cgccccgggg aaccgttccg ccaactcctt ggcccggccg acgtcgcgcg ccagcagcca
     6781 cagctcctca ccgcgctcgg cgagccgccg tgcgaccgcc gctccgatgc ccgatccggc
     6841 gcccgtgatc aagtgcgtac ccatgggggc gatcctacgg cgtgcccccg ggggcgggtc
     6901 agcccgcggc ggccgcccac gcctccaggt gggccagcgc gcccgcgccg tcctcggcga
     6961 agatcaccag ctcggagagg ggaacaggca ggaagccctc cgcctccatc cgctcgaact
     7021 gggccttgag cccgtcgtag aaaccggcgg tgttcagcag caccaccggc ttgctgtgca
     7081 tcccgtgctt gcgcagctcc aggatctcgg tcgcctcgtc cagcgtgccg gtgccgccca
     7141 ccatgacgac gatggcgtcg gcccgcgcca gcagctgcgc cttgcgctcg gcgaggtcct
     7201 tggtgacgac catctcgtcc gcgttggcgc gcgtcttgtc cgccaggaac tccacggaga
     7261 ccccgagcag tttcccgccg gcctcctgga cgccgtccgc catgaccttc atcagcccgg
     7321 tgtccgaacc gccccagacc agggcatgtc cgcgccgacc gatcgattcg gcgaattcac
     7381 gggcgggcac cacatagcgg tcgtcgaggt cggcggcgga acagaagacg cagatattca
     7441 tgccgttcag cctacgggca cgcggcggcc gccccacggg gcgcggggaa ggacaccggg
     7501 cccggccacg gagcggttcc gcggccgggc ccggcggggc gtctagatca ggccctggtc
     7561 cagcatcgcg tccgcgaccc gctcgaagcc ggcgatgttg gcgccggcca catagtcacc
     7621 gggccgaccg aagcgctcgg cggtctggta gcaggtgtcg tggatccccc gcatgatggc
     7681 ggcgagttcg ccctctgcgc gctcgaacga ccacgcctcg cgggcggagt tctgccgcat
     7741 ctccagcgcg ctggtcgcca ccccgccggc gttggcggcc ttgcccgggc cgaaggccac
     7801 gccggcctcc ttcagcagcg ccaccgcctc cggggtggtg ggcatgttgg cgccctcgga
     7861 gaccgccttg acgccattgc ggaccaggat ccgggcggcg tccgcgtcga gctcgttctg
     7921 ggtggccgac ggcagcgcca cgtcacaggc gacgtcccac acgcgcccgc cggcgacgta
     7981 cttcgccgaa ctgccgcgcc gctgcgcgta gtcgccgacc cggccgcgct cgacctcctt
     8041 gatctgcttg agcagcgcca ggtcgatgcc cttctcgtcg acgacgtagc cgccggagtc
     8101 cgagacggtc aggacgttgg cgccgagcgc ctgggccttc tcgatggtgt agatggcgac
     8161 gttgccggat ccggagacca ccacctgctg gccgtccagc tcctcgccgc gctgcttgag
     8221 catctcctcg gtgaacagca cattgccgta accggtggcc tccgtacggg ccttggagcc
     8281 gccccatgcc aggcccttgc cggtcaggac gccggcctcc cagcggttgg tgatccgccg
     8341 gtactggccg aagaggtagc cgatctcccg gccgccgacg ccgatgtcgc cggccggcac
     8401 gtcggtgtgc tcgcccaggt gacggtgcag ctcggtcatg aacgactggc agaagcgcat
     8461 cacctcggcg tccgacctgc cgtgcgggtc gaagtcgctg ccgcccttgc cgccgccgat
     8521 gttcagcccg gtcagggcgt tcttgaagat ctgctcgaag ccgaggaact tcacgatgcc
     8581 gaggttgacg gacgcatgga accgcaggcc gcccttatac gggccgagcg cgctgttgaa
     8641 ctccacccgg aagccacggt tgacccggat cttgccggag tcgtcctgcc agggcacgcg
     8701 gaacatgatc tgccgctccg gctcgaccat ccgctccagg accttggcgt ccgcgaactc
     8761 cggccgggcg gtgagcaccg gcgccagcgt ttcgaggacc tccagggccg cctggtggaa
     8821 ctccgcttca ccgggattcc gacggacgag ctcggcgtgc agggaagcca gctcggcggt
     8881 gagaccgctc tgcgtgaccc cagtgtgaac agtcgacatg acttccgttc ccttcgtggc
     8941 cgacgaaagc cgcgtgccgt ccggatcgcc gttgaaccgt cgacgcgggg ctccgatgtc
     9001 ccgtcgcatc gccgaccata tgcgccgggg accggcctat cgagggcggg ggtgctcgac
     9061 gcgccaatcc tgtacgcgat ttccccaact cccccgccgc gcagtctcag gccgcggcgg
     9121 ccggcgccgg ctcggcgttc cccgccgcgg cgggctcgcc tgcggcccgg acctcggcct
     9181 tgaccatctg ctccatcggc tcggcgcagc tgccgcccgc gaccaccatg gccagcagga
     9241 tcgccaccac cgtcagcacc gtgcccaacc acaccatgat gtgcaccggc agggcgtacg
     9301 caccgacgac cttgaccacg cactcgatca gcagggcgct cccccagacc gtcgagaacc
     9361 gccgctccag ttgccggaac cgcgcgctgc gcgcccacag ccggtcccat gcggcgttcc
     9421 cctcggggcc gcccttggtc acccagggcc ggagcccggc ggtcatcaac ggccgccggc
     9481 cgcgcaccga gagcaggatc gcgatcccga cgacgctgct gacgccgctg tccttggcca
     9541 tcatcagccg ggcgtcgccg gtcagggtgc tcgtcgccag ccccaccacg ttgacgacga
     9601 ggatcagcag cgcgaggccg ttgaccgtcc gctcccggac caggccccag atcgtgcgca
     9661 gcgccgggac cacgctgctc caggccagcg cagcgaccgt gctcatgccg aagccctcgg
     9721 cgaggaggaa gtacgagccg agcgggatcg cggcgtccac gagcagcggc gtcaggctct
     9781 gcaggagcgc cctgccctgg ctcgtggtgg cggtgacggt ggcggcttga gtcatgacgg
     9841 gtcccccggc gtgcgacgtg tgctgtcttc ctacgccctc atcttcgccg agggaccccg
     9901 ttccgcatca ggagcaagtg tcctgtcctc cccatgacat ttgtcattcc cggcgccggc
     9961 accgggagcg ggcgaggaag ggagatccgt cagaagcgcc ctaggccgcg tcggccagct
    10021 cctgtggcct gacgacgacg tacgcctgcc cctcggccgc ccggaagccg gtctcgcgcc
    10081 gggacaggaa cgcggtgatc ggggtgtcga tgtggtagca gagcaccgag gaggggacgg
    10141 agaagacgcc gggcgagtcc gcgaagagcg gggcctcggc cagcacgtag ttcagaccgg
    10201 cccgcaggtg ttccgcggag aggccgacgc tgtcaccggg ccggttcatc accacggccc
    10261 gcaccatgtc ctcgcaggcg gtggcgaatt cggcgtcctc ctcgaaggcc cggtcggtgc
    10321 gctcgcgtac ggcccggtac tcaggggtct cctggagctc ggacagggac cggacacgga
    10381 accgctcggc gtggtcgccc acgctctcca gcgagcgccg gagtctgcgc cgcagatcct
    10441 tgagtgtgcg tttgaccgac cgctcggcct cctgcgcgct gcggccctcg gcgatcagca
    10501 tctcgtcgat gtgggtgtcg acatagacga catcggtgcg ctcgaaacgc tgcccggccc
    10561 attgcagcag catgatggtg ttcttctggc tgaaataact gttgcccgca ctgattccaa
    10621 tgagggcgtg ctcaccgcgt tgccggatca ttcggctgcg gtcgccaagt atttcttccc
    10681 gcattccgtg gtccggcgcg gaaactaagc ctgcaagcat gctaagaagt ccttttgggg
    10741 ttgccccgga cagccgtcag ggggtttcta tttccggaag agcgtctgcc atttggcgac
    10801 acaggtcgtc cagaatcgcg cccatgtccc ggtcctcgcc catcggcgcg aacatgacct
    10861 cgtcgagacg ctcgcgcaca gcggtcagcc gtgccgtgct cccgccgtgt tcgtcgagga
    10921 gctggagcgc ccgacgggcc ccgtcggtac agcggtaaat tccgtagtcg gccggctcct
    10981 ccaggagtcc gcgaccgctg ctgagcagat aaacggcgag gagcgcgatc tcctcacgca
    11041 gttggggcgg cagcacggtt tccccaggat tcatagttga cgacctcatt cttggcgcgg
    11101 cgctgggagg ggacgagggc tgtcgcggga cggccgatcg ggaccacgag catcggctcg
    11161 atgtgttccg ggataccgag catgcttttg acgatctcgg acctgaagct gcccaccggg
    11221 catccgccca ggccggccgc gtgcgccgcg agcagcaggt tctccaccgc catggcgaca
    11281 cagagcttgc tggtgtcgta gatcttctgc gagagcttcg gggagaggtt gtcggtcaga
    11341 ctgcggtcga cgcaggccac gacgaagaac gcgggggttc ccagcacccc gggcgagtac
    11401 gcgcgcagcc ggcggaccgc ggcgggcctg cgcaccacca tgaacgacca cgcctgccgg
    11461 ttggaggcgg tcggcgcggc gagcatggcc tccaacagct gctcgatcag cgcgtcgtcg
    11521 accggctctt tcgcataatc gcggacggcg gtacgggttt tgaggaccgt ccacgcgtcc
    11581 ggcaaggatt ccggcggcga ttcagatgaa ctgtgagcca acatcaatcc ctttcttttt
    11641 gggcgcacct cacacccgcc gcggtgcggc gaatctgatg ggtggcgcct caccggtgct
    11701 cgcccgtcgc gacggatcca cgggcacggc cgggtccgac ggcaggcaat agcgcatcga
    11761 ttgccctggg gccggattca tgaccgaccc gcccggctga ccggtgactg agttcgattc
    11821 agttcggcgg aacaattttt cggactaggt gtaccagctc acgatctggc cggacaaggg
    11881 gggttgggag agcgttcgtc acagcgacgt gaatttaagc gctccgcagt accgaattca
    11941 cgccaccgac gcagcaaaat cggaaacctt cccaccggtt ttcggggtgg caaaaaccgg
    12001 gccgggcctg cccctgaagg gacgggcccg gcccggacgg gtcgttgtga cgcggtgcgg
    12061 tgcgctcgct ttcggacagc ctcacacgca acacgagccg cagacgcctc tggtgtgtca
    12121 gatgtctcag ccgcgtccgg catgtcgcgg acggtccggc cgagtcggcc cggctcaggc
    12181 caccgacgcg gcccggcggg tggtggcgat ggtggccgaa cccaccacgc gggtcccgtc
    12241 gtacaggacc acggcctgcc ccggggcgac gccccgcacg ggctcggtga aggagacccg
    12301 cagctcctcg ccgaccacct cggcggtgac ctcggtctcg ccgccgtggg cgcgcagttg
    12361 ggcggtgtag acggccgggc cgtcggccgg cggacggccg caccagcgcg gcttgatggc
    12421 cgtgagcgcg gtcacgtcca gggactcgac ggggccgacg gtgacggtgt tgttcaccgg
    12481 ggagatgtcc aggacgtagc gcggcttgcc gtcggcggcc ggggtgccga tgcgcaaccc
    12541 cttgcgctgg ccgatcgtga agccgtaggc gccctcgtgg gtgccgagct tcgtgccgga
    12601 ctcatcgacg atgtcgccct cggcgctgcc cagtcgcttg gcgaggaagc cctgtgtgtc
    12661 gccgtcggcg atgaagcaga tgtcgtggct gtcgggcttc ttggcgacga acaggccgcg
    12721 ccgggcggcc tcttcgcgga tctcggtctt ggtggtgggg gtgtcgccga gcgggaacat
    12781 ggcgtgcgcc agctggcggt cgtcgagcac accgaggacg taggactggt ccttggccat
    12841 gtcggtggcg cggtgcagct cgcgggagcc gtcctcgcgg aggatcacct gggcgtagtg
    12901 gccggtgcac accgcgtcga agccgagggc gagcgccttg tccaggaggg cggcgaactt
    12961 gatcttctcg ttgcagcgca ggcacgggtt cggggtgcgg ccggcctcgt actcggcgat
    13021 gaagtcctcg acgacgtcct cgcggaagcg ttcggcgagg tcccagacgt agaaggggat
    13081 gccgatgacg tcggcggcac gacgggcgtc gtgcgagtcc tcgatggtgc agcagccacg
    13141 ggccccggtg cggaacgacg tggggttctc ggacagtgcg aggtggacgc cggtgacgtc
    13201 gtggcccgcc tcggcggcgc gggccgcggc gacggcggaa tcgaccccgc cggacatggc
    13261 ggcgaggacg cggaggcggc ggggggcagc ggcatcagtc atagcccctc cagagtagac
    13321 ggaaccggac ggcgcccgga aagcgttgtg gagggcgtgg gagaggtgga gggcgtgcag
    13381 ggcgtggagg acacggcggc ggacgacgcg cgggacgcgg agcggacgtc cccgggcacg
    13441 gcggacgggg cgaccgacgg ggcggcggac gacgggaagc gcgccgggcg gcggctcacc
    13501 cggcgccggg tgctgctgct cggcggcggt gccgcggtgg ccgcgggggc ggcggcggtc
    13561 gcggcccgcg aggagctggc gtactggtgg gggcagctgc cggggaacag ccgcccccgg
    13621 aaggagggcg aggtcgactt cgccggtgcg cagtggtcgg ccgcctcccc ggcgaactac
    13681 cgacaggcca accgccccga cgactacacc gtcgaccgcg tggtgatcca cgtcgtccag
    13741 ggcagcttcg ccaccgcgct gaaggtcttc cgggacccct tccacgaggc gtcggcgcac
    13801 tacgtcgtcc gcggggacgg gcacatcgcg cagaccgtcc gcgaactgga cgtggcgttc
    13861 cacgccggga accgcggcta caacgagcgc agcgtgggca tcgagcacgc cggattcgtg
    13921 gaccggccgg agtccttcac cccggacatg tacgcggcgt cggcccggct gacggccggc
    13981 atctgccgcc ggtacgactt cccggccgac cgggagcatg tcgtcggtca catcgaggtc
    14041 ccggggacgg accacaccga ccccgggtcg cactgggact gggaccgcta tctgacgctg
    14101 gtccgggcgg agctgcgccg ccccgcggcc cggacgcggc cgggcacgac ctagctcagc
    14161 cccgcgcccc gggcgcgttc caccaccggg ccgatgacct ccgcaagggc cgccacgtcc
    14221 ttcgcggtgg aggtgtggcc gagcgagaag cggagggtgc cgcgggcgag gtcctgggac
    14281 atcccggtgg ccagcaggac gtggctgggc tgggcaacgc cggcggtgca ggcggagccg
    14341 gtggagcagg cgatgccctg ggcgtccagg aggagcagca gggagtcgcc ctcgcagccg
    14401 gggaacgtga agtgggcgtt ggccgggagg cggccggccg ggtccgggtc gccgcccagg
    14461 acggcgtcgg gggcggccgc ctgcaccgcc ttgatcaggt cgtcgcggag cgcgccgatg
    14521 tcgcgggcga actcctcccg gtgcgccacg gcgtgccggc cggccgcggc gaacgcggcg
    14581 atcgcggggg tgtcgagggt gccggagcgg acgtggcgtt cctggccgcc gccgtgcagc
    14641 acgggcacgg gggcgtgctc ccggcccagc agcagcgcgc cgatgccgta cgggccaccg
    14701 atcttgtggc cggagacggt catcgcggcc agtccggagg cggcgaagtc gacgtccagc
    14761 tggccgaccg cctggaccgc gtcggcgtgc agcgggatcg cgaactcccg tgccacctcg
    14821 gccagttcgc ggatcggctg gacggtgcca atctcgttgt tggcccacat cacggtggcc
    14881 agcgcgacgt cggcggggtt gcgggcgatc gcctcgcgca gcgcctcggc gtgcacccgg
    14941 ccgtagtggt cgaccggcag ccagtcgacg gtggcgccct cctgctcggc gagccactcg
    15001 acggcgtcca ggacggcgtg gtgctcgacg gggctgacga ggatccgggt gcgggccggg
    15061 tcggcggccc ggcgggacca gtacagcccc ttcaccgcga ggttgtcggc ctccgtgccg
    15121 cccgccgtga agacgacttc gctgggccgc gcgcccaggg aggcggcgag cgactcccgc
    15181 gcctcctcga cggtacgccg agcccgccgg ccggcggcgt gcagggagga cgcgttgccc
    15241 gtgacggtca gctgggcggt catcgcctgc accgcctccg ggagcatcgg ggtggtggcg
    15301 gcgtggtcga ggtaaaccat ggtgcgctga ttctacgagc caccccgggg cgcgtacccc
    15361 gcgcgggggc gcattccgca gggcgcacgc cccgatcggg ccgcggcggc tccccggtga
    15421 cccgccccgt cggccgtgcg ggccgcccgg tccacgcctg cgacatgcgg aggaggcgcc
    15481 gggccaacca cccccgatgg cgagggagtt cgccgggctg cgcggctact gcaccaggat
    15541 cgtgcgggcc agctggcggg actgggcgac caggcggtcc tcggagtccc agacctcggc
    15601 gtcctcctcc aggaagccgc cggccagatt gcgggtggtg atggcgaccc gcagcgggcc
    15661 gggggccggg cggtggcgga cgtggcaggt cagctcgacg gtggggaccc agccgcgcag
    15721 gcccagctcg aaggcggtgg gcggcagcgc gtcgacggtc agcaggaggg agagcgggtc
    15781 ggggtcgcgg ccgtcggcca ggccgaacca gccgcgcatc tcgcccttgc cggacggggc
    15841 gccgaccgcc cagcccacgg tcgccgggtc gagccggagg tccaggcgtc cggcgatcgc
    15901 ggtgctgccg gggatcgccg gccggccgtc gggggccatg ggggtccctc cgccccgttc
    15961 aggcgtgggg gaggtgccca ggcagtgctc gtagggcggg atggccgggg gcttggcggt
    16021 ggtgcggacg tcgtcaggga gggcggcgag gtcgccgtag gtggccagca cccgcatccg
    16081 ctcgacctcg ctgccgtcgt cggcgaattg gacgagggtg gcggcgccgg tggacagggt
    16141 gcggccggtg cggatcacct cggtgcggac gacggcgggg ccgggcaccg aggccgtcag
    16201 gtagtgcgcg gtgacggtga gcgggtccgg gtgcggcagg gcgtcgccca gggcgcggcc
    16261 catgagggcg aggaggtagc cgccgttgac ggcattgatg atcgtccagc cctcggagag
    16321 gtgcgcgtcg tagacgcccg gggcgctccg ggtgaccgcg gtgtcacggt cgaactcgct
    16381 gtttcctacg gtcaccgatg ccatgtcggc acgctacacg gctttattac cgaccggtag
    16441 tgtcaatttc aaggaacgga acggcggcgg acggggaacg cggccggagt cgccacttcc
    16501 gcggctgtca tcatgaccgc atgcttcatg tgctctacct gatcggcgtc gcggccttcg
    16561 ccgcgagcgg cgtgctggcg gcctaccgcg ccaacatgga cccgttcggc ggtctggtcc
    16621 tcgccttcgc cgcgtccatc tccggcggca ccctgcgcga tctgatcctg gaccggcggc
    16681 cgctgtactg gacgcacgac tgggtactgc tgacggtgat catctgcgtc ggcgtgggca
    16741 ccatcgtcta tctgcgcttc tggtcgctgc cgcggaagtc gctgctggtg gtggacgcga
    16801 tcgggctgtc cgtggtcacg gtgatagggg cccgggcggc gatctcggcg ggcgccaccc
    16861 cgctcgcggt gatcatcctg gcggtgctga ccggcgtggc cggcgaggtc attcgcgatg
    16921 tgctgtgcgg ggagttcccg ccgctgctgc tgcgcgagga cgtctacgcg atcgcggcgc
    16981 tggccggcgc ctgctgctat ctcctgatgg accgcctcgg ggccggggcc aaccccgccg
    17041 cggtggtctc ggcggggttg gtgttcgcac tccggatggg cgcgctttat ctggggctgc
    17101 acctgccccg gccgcagcag ctgcgcggcc gggggcgcga ggacgccggc tagccggtca
    17161 ccgctccgac agcacggggc ggctctgggt gtccagccag gtgtggaaga ggtcgcccag
    17221 ccgctgcccg gagatcttct cggccagcgc gatgaagtcg gcggtgtccg cgttgccgta
    17281 gcggtgccgc gcggtccagg ccggcagcag gcggaagaac gcccggtcgc cgatgcgttc
    17341 gcggagcgcc tggagggtca tcgcgccgcg ctcgtagacc gcgtcggaga acatggtgtc
    17401 ccgctgcggg tcggagacct tgatcttcca gaaggcgtcg tcggcgggta tcccctggta
    17461 cgccttgcgg aaggcgtcgt gggcggtggc ggtgcccttg tgctcggccc acagccactg
    17521 ggcataggtg gcaaagccct cgttgagcca gatgtccttc cactgccgga ccgagaccga
    17581 gtcgccgaac cactggtggg ccagctcgtg gacgatggtg ctctcgttgc ggacggcgga
    17641 gtaggccggc ttggactgca cctccaggga gaagccggcc tgcggcatgt cgtccacgat
    17701 cgcgccggtc tcctcgaagg ggtacggccc gaagaccttc gaccagtagt cggtggccgc
    17761 cgcggtgacg ccgtagacgt cgaccttgcc ggtcggcagg gtcgggtcgg tggcgacgta
    17821 gatcggggtg ccgccggggg tggtgccggt gcgcacgtcg aacttcccga tagtggcggt
    17881 ggccaggtac ggcgccatcg ggcggctctc gcgccagtgg aaccacgccc ggtcgccgtg
    17941 ctcgccggag cccaccagcc gcccgttgga gaccccggtc aggcccttgg gggcgtcgat
    18001 gcggatgtcg taggtggcct tctcgtccgg gtggtcgctg gaggggaacc acgtcgaggc
    18061 ggcgttgggc tcgcaggcca cgaagacgcc gtccttggtc ttcatccagc cgtactgcga
    18121 accgaagacg atcgggccgc tgagcggctg ggggacgccg tgatagacga cggtgaccgc
    18181 gaagcgctcg ccgcgggcga gcgggcggcc gggccggatg acgagttcgt cgccagttct
    18241 ggagaagcgg gcggggcggc cgtcgacccg gacctggtcg acggtcagct tctggaggtc
    18301 caggtcgaac gaggagaggt cctgggtggc ccgggcggtc agcgtggtcc tgccgtccag
    18361 ccggccggag tcggggtggt agctgacgcc gaggtcgtag tggaggggcc ggtagccccc
    18421 gttgcccaac ccggggaagt aggggtcacc gatgccgggg gcgcccggcg tggccgcggg
    18481 ggccgcggcg atggtggcgg ccgaggccac cgcggtggcc agggcgagcc aacgggagga
    18541 gcgacgcgca gaacgggaga gtgccatgag ccgtcccttc gagtacgcgg atgcgtgatg
    18601 aacaaccgcg ccgactctgc actctcccgt ccgtcttcac cagcgacttt gccaagtcgt
    18661 caggcgttac tgcccggttg atgccttacc gtccgaactt tcggtcgcct caacggagtt
    18721 gtctgactcg tcctcggggt ggtggcaggc cacctggtgc ccggtccgca actggatcag
    18781 cggcggctcg gtggtgatgc actcctcggt caccttccag cagcgggtgc ggaaccggca
    18841 gccggacggc gggttgatcg gcgaggggac gtcgcccttg agcaggatcc ggccgcgctg
    18901 ggtgcgccgc ttggggtcgg gcaccggcac ggccgagagc agcgccttgg tgtacgggtg
    18961 ccggggcgag gcgtagagcg agtcccggtc ggccagttcg acgatcttgc cgaggtacat
    19021 caccgcgatc cggtccgaga cgtgccggat gaccgagagg tcgtgcgcga tgatcacgta
    19081 ggtcaggccc agctcctcct ggaggtcgtc catgaggttg acgacctggg cctggatgga
    19141 gacgtcgagg gcggagaccg gctcgtcggc gaccaccagc ttcggcttga gggccagcgc
    19201 ccgggcgatg ccgatgcgct ggcgctgacc gccggagaac tcgtgcggat agcggttgta
    19261 gtgctccggg ctcaggccca ccagctccag cagccgctgc acctccttct tgaccccgcc
    19321 ctcgggctcg acgccctgga gccggaaggg ggtggagacg atcccgccga tggtgtgccg
    19381 cgggttcagc gaaccgtacg ggtcctggaa gatcatctgg atgtcgcggc gcagcgggcg
    19441 cagccggccc ggggacaggt gggtgatgtc ctggccctcg aactcgaccg agccgccggt
    19501 cggttcgtcg agccgggtga tcagccggcc catcgtcgac ttgccgcagc cggactcgcc
    19561 gacgacgccc agtgtctccc cggggaagac gtcgaagtcg atcccgtcga ccgcctggac
    19621 ggcgccgacc ttgcgcttga gcaggccctt ggtgatcggg aagtgccgga ccaggccgcg
    19681 gacccgcagc agcggctcgt cctgggcggc gcgcccggag cgctcggcac gcccgacctc
    19741 aggggtcgcc gcgggcttcg cgggcttctc ggccttctca ggctcctccg ccttctccgt
    19801 gttcaccgcc ttctcggcac tctcgacatt cccggccggc tcggccttct cggcgctccc
    19861 ggccttctcg gtctgctccg cgctctcgac ccgctcggcc tgttcggcgt tctcggcctg
    19921 ctcgggcttc gcggtcgcct caggcttctc agtcttctcg gtcacagctt cggcgcaatc
    19981 tcttcggtcc agatacgctc ccgctcctcc cgcggcaggt ggcaggcgga gaagtgccgg
    20041 ccgtcgacct gctgcagttc ggggcgcacc gtgcgggtga cgttgtcctt ggggacgtcc
    20101 gcgtacggac aacgggggtt gaaggcacag ccggacggca cgttgatcag gctgggcggc
    20161 gagcccttga ccgggatgag ccggtcggtc tggtcacggt cgatccgcgg catggagccg
    20221 agcaggcccc aggtgtaggg gtgctgcggg gtggcgaaca cctcgtccga ggggccccgc
    20281 tccacgcacc ggccgccgta catcaccagc aggtcgtcgg cgagctcggc gaccacgccc
    20341 aggtcgtggg tgatgatgat gaccgccgag ccgaactcct tctgcagatc gcggatcagg
    20401 tccaggatct gcgcctggac ggtgacgtcc agggcggtgg tcggctcgtc cgcgatcagc
    20461 agctcggggt tgttgaccag cgccatggcg atcatggcgc gctggcgcat accgccggag
    20521 aactggtgcg gatggtcgtc cacccgcttg tccggctgcg ggatgccgac ccggtcgagc
    20581 atctctacgg cgcgcttgcg ggcggtcttc ttgtcgacgt cgtggtggac ccggtacgcc
    20641 tccacgatct gctggccgac cgtgtagaag gggtgcagcg cggacagcgg atcctggaag
    20701 atcatcgcca tctcgcggcc
//
