LOCUS       NZ_LJSN01000003        21077 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces noursei strain JCM 4701 scaffold3, whole genome shotgun
            sequence.
ACCESSION   NZ_LJSN01000003
VERSION     NZ_LJSN01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
REFERENCE   2  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method :: SPAdes v. 3.6; SMRT Analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891315.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 20:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,947
            CDSs (total)                      :: 8,851
            Genes (coding)                    :: 8,489
            CDSs (with protein)               :: 8,489
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 362
            CDSs (without protein)            :: 362
            Pseudo Genes (ambiguous residues) :: 0 of 362
            Pseudo Genes (frameshifted)       :: 118 of 362
            Pseudo Genes (incomplete)         :: 301 of 362
            Pseudo Genes (internal stop)      :: 23 of 362
            Pseudo Genes (multiple problems)  :: 74 of 362
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1152518
            Orig. end                         :: 1173595
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJSN01000003.1.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21077
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21077
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21077
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11077](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11077)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    559..575
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.39"
                     /tool="antismash"
     misc_feature    complement(718..731)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    complement(854..868)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.23"
                     /tool="antismash"
     gene            868..1242
                     /locus_tag="AOB60_RS26800"
                     /old_locus_tag="AOB60_25755"
     CDS             868..1242
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602486.1"
                     /locus_tag="AOB60_RS26800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25755"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_073448751.1"
                     /transl_table=11
                     /translation="MKAQAADAGKPARELPGPHTDEITMVGVLQALADPQRLQIVLRIA
                     EHAGESCTVIGDGINLHKSTLSHHYRVLREAGVTQTWAQGRSRFTTLRRDDLDARFPGL
                     LDSVLAALPHDGTPILPARP"
     misc_feature    1619..1634
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.93"
                     /tool="antismash"
     gene            2084..3025
                     /locus_tag="AOB60_RS26810"
                     /old_locus_tag="AOB60_25765"
     CDS             2084..3025
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557399.1"
                     /locus_tag="AOB60_RS26810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25765"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_102925280.1"
                     /transl_table=11
                     /translation="MDALLAVRARGITKWFGDVVALDGVDLDVTQGQIHGLVGPNGAGK
                     TTLLGLLLGLAVADSGSLAILGAPVGRALDAPDGVAGFVDGPGLYPSLTARQNLAALAA
                     LRGDDARTTAIDDALAQVGLTDVADDRARGFSLGMRQRLGLAAALLTKPRLLVLDEPSN
                     GLDPAGKKHVHGVLTRLATDGTGVVLSSHRMDDVEALCSDVSILAAGRVVFSGPLSKLA
                     AEERELDYRVRTSDAHAARRLAAETAGIRLVDDAGARHDAQVLVVRAPVPALDELVVRL
                     VRAGIAVRELSPVVSPLEAAFLALTEPEEAGR"
     gene            3022..4395
                     /locus_tag="AOB60_RS26815"
                     /old_locus_tag="AOB60_25770"
     CDS             3022..4395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557400.1"
                     /locus_tag="AOB60_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25770"
                     /product="ABC transporter permease"
                     /protein_id="WP_102925281.1"
                     /transl_table=11
                     /translation="MNAPLTHAHARPHGAGTRRASVARGYRFELVKLVSQWRIRLLVLA
                     CWIAPALFVAAVSQQSTLPVDTLFGRWMHATGWAGPLVTLGFAGTWALPLLTSVVAGDV
                     FAAEDRLGTWRHLLVAVRSPRRIFAAKAFASLTVLLLLVAGLACSSAAGGVVAAGNQPL
                     VGLDGHLLTPANAAVKVLLAWVCVLAPTLSLAGIGLLGSVALGRSPMGLLLPVLVALAM
                     QLAQMMPLPVAVRLALPSYAFIAWNGLFTGPAQLAPLLIGTGVSLAWAVLATALAYLLF
                     LRRDFTNLSYDGSGLRTVTVGVLPLAGLVAVTVAVLTTSATATASGSGIEQDKVQRSVA
                     TAFAHLYRIQTEQLHRPHVTEAQLKAEATCTKGGLQTAAQGAGNDWRCVVSWHLPGVDA
                     AGQAIYQLDMTPDGRFMADGDGPKEVNGYFLVRTPQGDAPNPLWQFDGNVALLATSKG"
     gene            4400..7153
                     /locus_tag="AOB60_RS26820"
                     /old_locus_tag="AOB60_25775"
     CDS             4400..7153
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054569.1"
                     /locus_tag="AOB60_RS26820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25775"
                     /product="bifunctional YncE family protein/alkaline
                     phosphatase family protein"
                     /protein_id="WP_102925282.1"
                     /transl_table=11
                     /translation="MQVIRRRRHDANDHAGNLRRRFSRRGTLATATAVVLAATAGIGYA
                     QTHQFGTARVGQQTADGQVVSSDQYIAPYGDRLVIDNGKIMSSSVSPDGTHVAASLTDG
                     GAALAIVDRKNWKVQQFVGASASSTPRISSNSVGQEGPTYSPDGKQLWLGQTDGYTKFT
                     VNPDGSVSNPTYIKIPADGTKHALVGEPVFSSDGTTVYAAVNGQNKVVALDAATGAVKH
                     SWAVGNAPRDMVKVGHKLYVSNEGGRPAKPGEPTINSYDTQVPADPKTGATTTGTVSVI
                     DLAKPGAAVKSIDVGLHPTALYAKGGALFVTNTATNDVSVISTTGDKVVQTIATRPWPE
                     ASVGYEPNAVTLTDDGHLLVTLGRADAVAVYKFKSPQEPVSYVGLLPTDYFPSEIATVG
                     KQVLVSNTRGIDARRPTTSGAHGTHDTTSSLQRFTLPDDSIIRSETAKVFKQNGWTGDS
                     VKKTDGTSHAKPIAVPKRLGDPSTIKHVFLIVKENRTYDQVFGDLPQGNGDPKLTQFGE
                     NVTPNQHALAKQFGLYDNTYDIGTNSAEGHNWLMQSDNPEYTESSAGEYQRSYDTENDA
                     LGHQKSGFLWTGAQAAGRSVKDFGEFQSVESKPSGASWQNLYCDARTMDATGKPTAYPI
                     KTGSAIPSLNDVSVPGFPMFDLDVPDVYKYQVWKQDFEKNGPANLNMLWFSNDHTGGPA
                     SPSAQVADNDLAVGKMVDKISHSKYWKDSAIFVVEDDSQAGLDHVDGHRAPIQIISPWA
                     QHGRTDSHYYTQITMIRTIEQILGIHPMNQKDSAASPMSGAFTAYPDTAPFKAQPNRVP
                     LTDGLKTQPPCGSDNPAAQSPRAAAVSPATVPADKQDLAATWDTWKSKQRLTGPHAVPD
                     YANPAQMNHLTWYETHNWNRPYPGENKIFAPQDVPGAYLPSSENDG"
     gene            complement(7883..8623)
                     /locus_tag="AOB60_RS26830"
                     /old_locus_tag="AOB60_25780"
     CDS             complement(7883..8623)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018555356.1"
                     /locus_tag="AOB60_RS26830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25780"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_258018313.1"
                     /transl_table=11
                     /translation="MRPVPEGSAGPGEQAAPNDYDSFAEAYSTQNETSLFNAHYERPAM
                     LDLAGDVAGRRILDAGCGSGPLSAALRDRGAIVTGFDSSTKMLELARKRLGDDAALHLA
                     DLGSPLPFPDAAFDDVVASLVLHYLEDWTAPLAELRRVLTPGGRLIVSVDHPSIGLVQP
                     GIDYFATYKHSEEWTLGGHTALMTFWHRPLHAMTEAFTAAGFRINVISEPLPAPGAREL
                     FPDIFVDKPSGAFVCFLFFVLQAD"
     gene            complement(9123..9416)
                     /locus_tag="AOB60_RS26835"
     CDS             complement(9123..9416)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS26835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_146051214.1"
                     /transl_table=11
                     /translation="MVVAEVPGPAMPRRGMMSNVHGQPLVSQGPRGNIVINPDDARGLK
                     LQHASAACCGATPDGGMNQMCACGSLVATLSSDCCLPYELHLSAGHVRAVRP"
     gene            complement(10001..11077)
                     /locus_tag="AOB60_RS26840"
                     /old_locus_tag="AOB60_25790"
     CDS             complement(10001..11077)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540840.1"
                     /locus_tag="AOB60_RS26840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25790"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_102925284.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4e-39, bitscore:
                     132.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADNAAGVHERLAGYRDRFNGVFANYFDSVAEQGPPRNSFVPEA
                     LELVRDMSLRGGKRLRVALLYEAARLVAPDAVPGLDEAALSIELLQTHGLIHDDIIDDS
                     PVRRGAPSVYYAYRERFPDRPQTALGLAVLAGDLAAFLSVQVLLTAPVPRELRQAMAAV
                     QATAGADTVRGQFLDLERDFGPVPDREVLDTVSEYKSARYSVLAPLQLGLLAAGADPAA
                     HENELARYARLLGVSGQMRDDYLDLFADAGTVGKPAGSDLREGRRSYAVCALLAATSGA
                     ERAVVESALAGPGCPPQTVERIQDIARRHGVDNELLAEIRRCAQEAAAVAANWRGRWRD
                     EAVEFFEQLPLWGVLRAQ"
     gene            complement(11385..12485)
                     /locus_tag="AOB60_RS26845"
                     /old_locus_tag="AOB60_25795"
     CDS             complement(11385..12485)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541840.1"
                     /locus_tag="AOB60_RS26845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25795"
                     /product="alkene reductase"
                     /protein_id="WP_102925285.1"
                     /transl_table=11
                     /translation="MMKLLTPFTSAELTLSNRIVMAPMTRFRAEEDGTPLPIVADYYRQ
                     RAGAGLIVTEGIWPSLRGQSGWRIPGLESERHVSAWQHVTEAVHDAGGRIFAQLMHGGR
                     QGHPRSRILGDIPAGPSAVPVPGPVHVRDGKADPVIPRAMTHDDIRTAIADHVAAARNA
                     IRAGFDGVELHGANSYLIHQFLADNTNLRTDAYGGDISGRIRFPLELVQAIADAVGAGR
                     LGLRLSPGNPQFGMEEADPAPVYRALLARLDGLGLAYLHLTDDDRYPALADLRPRWHGT
                     LIANVGENHAPTTREAGEAVLASGRADLVSYGRLFISNPDLPHRFAASLPLNTHIDQSA
                     LYGHGAAGYTHYPAWQELQPVATRQP"
     gene            12545..12904
                     /locus_tag="AOB60_RS26850"
                     /old_locus_tag="AOB60_25800"
     CDS             12545..12904
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (96-112). E-value:
                     0.0014. Score: 10.1. Matches aSDomain:
                     nrpspksdomains_AOB60_RS26850_PKS_Docking_Nterm.1"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540838.1"
                     /locus_tag="AOB60_RS26850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25800"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_073448726.1"
                     /transl_table=11
                     /translation="MRIGELARRTGVSERSLRYYEQQGLLASERTPGGHRDYPERAVDR
                     VIRIQELFAAGLCSKKIAQLLPCIRDHDGGPAVTATPWLVQELRAERERINRTIADLRR
                     SQATLDEVIDAASRP"
     aSDomain        12833..12880
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOB60_RS26850_PKS_Docking_Nterm.
                     1"
                     /evalue="1.40E-03"
                     /label="AOB60_RS26850_PKS_Docking_Nterm.1"
                     /locus_tag="AOB60_RS26850"
                     /protein_end="112"
                     /protein_start="96"
                     /score="10.1"
                     /tool="antismash"
                     /translation="RTIADLRRSQATLDEV"
     gene            13050..13208
                     /locus_tag="AOB60_RS46235"
     CDS             13050..13208
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS46235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_180990286.1"
                     /transl_table=11
                     /translation="MESWFVLQLTVLDGEITRYRFYEDSLTVARAWATTTAGADGQVQE
                     AHGGTTG"
     gene            complement(13406..14404)
                     /locus_tag="AOB60_RS26855"
                     /old_locus_tag="AOB60_25805"
     CDS             complement(13406..14404)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119290.1"
                     /locus_tag="AOB60_RS26855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25805"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_073448725.1"
                     /transl_table=11
                     /translation="MLTALGLDVVAESVYRAMLADPLGGVAELVARVGKPEDEVRDALD
                     LLSELALVRPSIEQPGRPRAVSPEIGMEILMARQQADLAAQQQRLETSRAVAAQLIAEY
                     ADLRPAASSPGVEQLIGIEQIRDRLARLTRDVTTDVMSFAPGGAQPAAQMKASRPLDEQ
                     LLGRGVRIRTVYLSSVRNDQPTVDYANWLTDLGGQIRTTPALPTRMIITDGSTAVIPVS
                     SEDTATGAVVLTSQGTLTALCALFEGVWSCAQPLGEAAPRNSHGLNPQESTTIALLAQG
                     HTDEAIAKRLGVSQRTARRIATDLMERLGARSRFAAGARAVQHGWLPSQPT"
     gene            14653..14985
                     /locus_tag="AOB60_RS26860"
     CDS             14653..14985
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS26860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143179756.1"
                     /transl_table=11
                     /translation="MVRSQTHDGDGVEHVTVHPDALPHPVVGLYVRADSLAAAEYRAAR
                     VCRLLLGCAGFDGWSLPVVEAPMVAPFYESRLSDPGPAGPAVDGCGQGHFGPAENPSTP
                     SDQQRK"
     misc_feature    14881..14883
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15373..16572
                     /locus_tag="AOB60_RS26865"
                     /old_locus_tag="AOB60_25815"
     CDS             15373..16572
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955810.1"
                     /locus_tag="AOB60_RS26865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_25815"
                     /product="FG-GAP-like repeat-containing protein"
                     /protein_id="WP_102925287.1"
                     /transl_table=11
                     /translation="MPETPRATSRTAWKSAATAALTLAGLTLSLVSVAPATAASLGTWD
                     KVAQCESSGNWQINTGNGYYGGVQIYLPTWNAYGGREYATYPHQATKQQQILIAEKILA
                     GQGAGAWGSCGAGAGLGGDHADPYPTTPPAPVGMVHLTAADFTGDGRKDLVGVESATGK
                     LWLYPGKGDGTFGDRVQIGTGWNTMSKLAAADYTGDGKADLLAVENSTGNLFLYPGTGS
                     AVGMNTLGARTQIGSGWGGMRDLTAIDVNKDGKPDLVAVDTNGSLWAYPGTGSLAGSST
                     LGGRVQIGSGWGSMAELASPGDLDSDGKADLVAVDPAGALWKYPGTGALNGSNTFGARN
                     QIGSGWNSMHQLVGADFNNDGKGDLDAVQAQAGSTGGLYFYPGNGSGGLADRARIGTGW
                     "
     gene            16675..18027
                     /locus_tag="AOB60_RS26870"
     CDS             16675..18027
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024907.4"
                     /locus_tag="AOB60_RS26870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VCBS repeat-containing protein"
                     /protein_id="WP_102925288.1"
                     /transl_table=11
                     /translation="MSTFAAKLKKTSVATLVVAAAVTGLGIAGPAAAPAHAAGTSAVGG
                     EITTAEVMSRAQYWVDRAVPYSQSDYDPDPQGRNYRQDCSGFVSMAWHLNTSLTTWTLP
                     QVATRLSSLDELQPGDMLDNIDSHVVLFGGWADSGRTTAKVWEEAHPGTTARVNSSYYT
                     RSYINSHGFRPYRYTKIVESKPTPKDVGMTNLTGGDFGGDGKADVVAVEASSGKLFYYP
                     GIGGGRLGDRVQAGTGWNTMSELTSGYFTGSGKLDLAAVDNDGVLWIYPGNGNGTFGNR
                     IKAGTGWDGMHDLAGADLNKDGKSDLVAVESSTGKLYAYPGNGNGTFGNRVQIGSGWNG
                     MDQIVSPGDMNKDGNADIVAREVSTGNLYVYPGTGSFNGTNTLGSRTQIGSGWDSMTNL
                     VSGDFNGDGIGDVDAVQAKVGETGTFYSYPGTGAINGTNTLGARVQIGTGW"
     gene            18159..20276
                     /locus_tag="AOB60_RS26875"
     CDS             18159..20276
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024907.4"
                     /locus_tag="AOB60_RS26875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VCBS repeat-containing protein"
                     /protein_id="WP_102925289.1"
                     /transl_table=11
                     /translation="MARRHLLRRTRTRGRGAAVAGVMALASLATGSHAVAGTAPDGTTA
                     TYNSITRTGTDGMGLQSDNGREARRVSAFASAHPALGRVTTADVLADTSGAGAGRTLCH
                     PTNIAGAQGFCWSAADDNTGSWIPQGLTGSGESPRSQALVNGRKVLITSWYGASGTERV
                     TLADVTDPAHVTYRHVQLAALDDTGDNFVPITGGHAHAVVWAGSKLYVASTGSRFDVFD
                     LNEIWKMDVTTDTSFGMDAKGKAHGAGHRYVLPRVGTYAFTGQGTGCGSYAGVPQRPCI
                     TAASLDLSGSQPALVTAEGDPGGVEGQFGKATAPVVRWPIDPVTGVLKADAGGRVRAHE
                     AFASPMGGTQGIAMNNGRFVLSGPCPEFVPAEHQPDPEHIRNFPGCLYHARPGEPVRLV
                     TRTPTNPENLSYWPGTDQLWTVNESTGERVVVNTPWPKDPAPVGMVHLTAADFTGDGRK
                     DLVGVESATGKLWLYPGKGDGTFGDRVQIGTGWNTMSKLAAADYTGDGKADLLAVDSAT
                     GDLYVYSGTGTANGMNTLGARTRIGTGWNSMRELTAIDINDDGRADLLAVDTDGALWAY
                     PGAGSLADGNTLGNRVRIGTGWDTMTELTSPGDLNADGRADLVAVDRSGALWAYPGTGS
                     LNASDTLGSRTRIGTGWDTMRQLVGADFDNDGKGDLEAVQAPAGSTGALYFYPGTGNTA
                     LGSRTQTGTGW"
     gene            complement(20613..20981)
                     /locus_tag="AOB60_RS26880"
                     /old_locus_tag="AOB60_25830"
     CDS             complement(20613..20981)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS26880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_25830"
                     /product="hypothetical protein"
                     /protein_id="WP_073448720.1"
                     /transl_table=11
                     /translation="MMLRLRRMAMATACTAALAGSLTLGAGVAFAGNSGQQIHFQDRRH
                     KVASIWLDGKNQNGKPVQFCWMTPATDTYIRDNWWVGRMDITEFRNRHCDHENNGVVGY
                     LHPNVPRMQDSDWYLVRN"
     misc_feature    complement(20916..20918)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 cgcccaggcc ccagccgaag agcagaaggg tgagcttgac gatggagtcg ccggtgactc
       61 cgtgcaggaa cgggccgatg taggtgtaga ggaagtaggc actgcactgt gccaagatcg
      121 tggtgcccag aatccccagg atccaggggc gcttgagggg ggcgagccgt tgcgccagtg
      181 tggcggcggg cagggaaacc ttgggaagcc cgaagccgat gcccagggcg gcgaggaggc
      241 cgagtgccgc gacggcccac aggctcagat gccaatcggc gccgccgatc agagtgccca
      301 gtggcaggcc cagggcggtg gccgtgctca gtccgcccat gacgaaggcc agggcggcgc
      361 cgcggcgttc ggcgggtgcg acggctgcgg cggtgctgga ggcggcagag gtgatgatgc
      421 ccgcaccggc agcggtgacg atgcgggaga gcagtaccac ctcatagctg gtactcagtg
      481 ccgtggccgc gttgcccacg acgaagacgc tcagggccaa caccaaggcg gtccgccggt
      541 tcagcccgct ggtggccgcg cccagtaccg gggcgcacac cgcgaaggtc agggcaaagg
      601 cggtcaccag ctgcccggcg gccgcagtgg tcaccccgag gtccttggag atgtccggca
      661 acagtcctgc gatgacgaat ccgtcggtgc cgacggcgaa cgtcgccagc gctaacggaa
      721 tcagccgttt gaacacaact caccactttc ctaggacagc tgatacagcc accaaggtag
      781 ccaacagttg gatgctaatc caactattac tcggggtcgc caccaacccc tgcctgccgc
      841 atccaccacc tcgtaaactc gatgttcatg aaggcgcagg cagcagacgc aggcaaaccg
      901 gcacgcgagc tcccgggccc gcacacggac gagatcacga tggtcggagt gctgcaggca
      961 ctggccgacc cgcagcggtt gcagatcgtg ctgcggatcg ccgagcatgc gggagagagc
     1021 tgcaccgtga tcggcgacgg catcaacctt cacaaatcga cgctctccca ccactaccgc
     1081 gtcctgcgcg aagccggcgt gacgcagacc tgggcacagg gacggtcacg cttcaccaca
     1141 ctgcgtcgcg acgacctcga cgcccgcttc cccggactgc tggactccgt actagcagca
     1201 ctgccgcacg acgggacgcc gatcctgccc gcccgcccgt agatccccaa ctgtcgtgca
     1261 cgggacggcc agttgccacc gaccggctcc gcgcccattc atccacaaag ggatcgtgcg
     1321 cagaaggggc agcgggcaag agcccgctca gacgaaccag cgtgccgggg tcgagcccga
     1381 ggagcacttg tccctgcagt tccagattgg tgctcggcag cagcatggcg tgcagcgcga
     1441 agccctggga tgtcgccgag ggctgcagag accagttctg ctgggtgttg gcctggtcgc
     1501 agtgctccgg ctcgacgcga gggttgttgt cggtgttgaa gtcgaggcac ttctgcgtct
     1561 tgtcgttgcg gatcaggaag cttccgtcac cgttgagcaa gatgctccag ttcgccatct
     1621 gatgtcttgt tgacgacgat ctcggtcccg tagtcgggcg agttcttcgc cggatccagg
     1681 gacggcgcga ggccgtccgc cgcaccggcc cgtgggtggc gactcggtga tcatgattgg
     1741 tctgtgctcc ttcggcggtt cttgcctgcg aggcgggttc gatgaccgcc cttgtgccgc
     1801 agcaacgcag caacccgttc cgaaatggcg gcggggaagc actccgcccc cggctgcggc
     1861 ctgctgcggc ggcggtgtca acgtacgggc cccatgtgcc gttacatccg tcaactgacc
     1921 gaggcttacg ggacgccgac acccctgcgc tccgcagcgc ccgcccgggc ttggtcacgg
     1981 cgcataccgg tcgtcaaccg tttcttgagc attcagctga ctgctcctga acgttgccgc
     2041 gcaccgcctc tacggtcctt gaggctctcg aaggaaggga ctcatggacg cactcctcgc
     2101 agtccgggct cgcgggatca ccaagtggtt cggcgatgtc gtcgcgctcg acggcgtcga
     2161 cctggatgtg acgcaggggc agattcacgg cctggtcgga ccgaacggcg ccggcaagac
     2221 gaccttgctc ggccttctgc tgggtctggc cgtcgccgac agcggcagcc tggcgatcct
     2281 gggtgcgccg gtcgggcggg cgctcgacgc tcccgacggt gtcgcgggct tcgtggacgg
     2341 acccggtctc tacccctcgc tcaccgcccg gcagaacctc gccgcgctgg ccgctctccg
     2401 cggtgacgac gcgcggacca cggcgatcga cgacgcactt gcgcaggtcg ggctcaccga
     2461 tgtcgccgac gaccgggctc gcggcttctc cctcggcatg cgacagcggt tggggctggc
     2521 cgcggcgctc ctcaccaagc cccggctgct cgtgctcgac gagccgtcca acggcctgga
     2581 cccggccggc aagaagcatg tgcacggtgt cctgacccgg ctcgcgacgg acggcaccgg
     2641 cgtcgtgctc tccagccacc gcatggatga cgtcgaggcc ctgtgctccg acgtcagcat
     2701 cctcgccgcc gggcgggtcg tcttctccgg gccgttgagc aaactggccg ccgaggagcg
     2761 ggaactcgac taccgcgtac gcacctccga cgcgcacgcc gcccgccgac tggccgccga
     2821 aacagccggg atccgcctcg tcgacgacgc cggggcacgg cacgacgcgc aggtgctcgt
     2881 cgtgcgcgcg ccggtgcctg ccctcgacga actggtggtg cggctggtgc gggcgggcat
     2941 cgcggtacgc gagctttccc ccgtggtgtc gccgctcgaa gcagcgttcc tcgccctcac
     3001 cgaacctgag gaggccgggc gatgaacgcg cccctcacgc acgcccacgc ccggccccac
     3061 ggtgccggta cccgccgcgc ctcggtggcg cgtggctacc gtttcgagct ggtcaagctg
     3121 gtctcgcagt ggcggatccg cctgctggtt ctcgcctgct ggatcgcgcc ggcgctcttc
     3181 gtcgccgcgg tgagccaaca gagcacgctc cccgtcgaca cccttttcgg ccgctggatg
     3241 cacgccaccg gatgggccgg accgctggtg acgctcggtt tcgcgggcac ctgggcactt
     3301 ccgctgctga cctcggtggt cgccggcgac gtgttcgccg ccgaggaccg actcggcacc
     3361 tggcgccacc tgctcgtagc ggtccgatcg cccaggcgga tcttcgccgc aaaggcgttc
     3421 gccagcctca ccgtcctgct gctgctcgtg gccgggctgg cctgttccag cgcggccggt
     3481 ggggtcgtgg cggccggcaa ccagcccctg gtcggcctcg acggccacct gctgacgccg
     3541 gcgaacgccg ccgtcaaggt cctgctcgcc tgggtctgcg tcctcgctcc gaccctctcc
     3601 ctcgccggga tcggactgct cgggtccgtc gcgctggggc gctccccgat gggactgctg
     3661 ctgcccgtcc tcgtcgccct cgcgatgcag ctcgcccaga tgatgccact gccggtcgcc
     3721 gtccgcctcg ccctgcccag ctacgccttc atcgcctgga acggtctgtt caccggcccg
     3781 gcccagctcg ccccgctcct gatcggcacc ggtgtcagcc tggcgtgggc cgtgctggcg
     3841 acggcgctgg cctacctgct gttcctgcgg cgcgacttca cgaacctgag ctacgacggc
     3901 tcggggctcc gcacggtcac cgtcggagtc ctgccgctgg ccgggctggt cgccgtgacg
     3961 gtggcggtcc tcaccacgtc ggccacggcc acggcctccg gctccgggat cgagcaggac
     4021 aaggtgcagc gctcggtcgc cacggcattc gcccacctgt accgcatcca gaccgagcag
     4081 ctgcaccggc cccacgtcac cgaagcccag ctgaaagccg aggcgacgtg caccaagggt
     4141 ggcctccaga ctgccgcgca gggggcgggc aacgactggc gctgcgtcgt ctcctggcac
     4201 ctccccggcg tcgacgccgc cggccaggcc atctatcagc tcgacatgac cccggacggg
     4261 cggttcatgg ccgatggcga tggaccgaag gaagtcaacg gctacttcct ggtgcggacc
     4321 ccgcagggcg acgcacccaa cccgctgtgg cagttcgacg gcaatgtcgc gctgctcgcc
     4381 acctcgaagg gataactcca tgcaggtcat acgccgccgc cggcatgacg cgaacgacca
     4441 tgccggcaat ctccgcagac gtttcagccg ccgcggcacc ctggccacgg ccaccgcggt
     4501 cgtcctcgcc gccaccgccg gcatcggtta tgcccagacc caccagttcg gcaccgcccg
     4561 ggtcggccag cagacggctg acggccaggt cgtctccagc gaccagtaca tcgccccgta
     4621 cggcgatcgc ctcgtcatcg acaacggcaa gatcatgtcg tcctcggtca gcccggacgg
     4681 cacccacgtc gcggcctcgc tcaccgacgg cggggcggcg ctagccatcg tcgaccgcaa
     4741 gaactggaag gtgcagcagt tcgtcggcgc ctccgcttcg tcgaccccgc gcatcagcag
     4801 caactccgtg ggccaggaag gccccacgta ctcgcccgac ggcaagcagc tgtggctggg
     4861 ccagaccgac ggctacacca agttcacagt gaacccggac ggcagcgtca gcaacccgac
     4921 gtacatcaag atcccggcgg acggcaccaa gcatgcgctg gtgggcgagc cggtgttctc
     4981 gtccgacggc accaccgtgt acgccgcggt caacggccag aacaaggtgg tcgccctcga
     5041 tgcggcgacc ggtgccgtca agcacagctg ggccgtgggc aacgccccgc gggacatggt
     5101 caaggtcggc cacaagctct acgtcagcaa cgagggcggc cgtccggcca agcctggcga
     5161 gcccacgatc aactcctacg acacccaggt gcccgccgac ccgaagaccg gtgccaccac
     5221 caccggcacg gtcagcgtca tcgacctggc gaagccgggt gccgccgtca agagcatcga
     5281 cgtcggtctg caccccaccg ccctgtacgc caagggcggg gcactgttcg tcaccaacac
     5341 cgccaccaac gacgtgtcgg tcatcagcac caccggcgac aaggtcgtgc agaccatcgc
     5401 cacccgtccg tggccggagg cgtcggtggg ttacgagccc aacgcggtga cgctcaccga
     5461 cgacggtcat ctgctggtga cgctcggccg cgccgacgcg gtcgccgtat acaagttcaa
     5521 gagcccgcag gagccggtca gctacgtcgg cctgctcccc acggactact tcccctcgga
     5581 gatcgccacc gtcggcaagc aggtgctggt ctccaacact cgtggaatcg acgcccgccg
     5641 ccccaccaca agcggtgcgc acggcaccca cgacaccacc tccagcctgc agcggttcac
     5701 cctgcccgac gacagcatca tcaggtccga gacggccaag gtcttcaagc agaacggctg
     5761 gacgggcgac tcggtcaaga agaccgacgg cacgagccat gcgaagccga tagcggtccc
     5821 gaagcggctc ggcgacccct cgacgatcaa gcacgtcttc ctgatcgtca aggagaaccg
     5881 gacctacgac caggtcttcg gcgacctccc gcagggcaac ggcgatccga agctgacgca
     5941 gttcggcgag aacgtgacgc cgaaccagca tgcgctggcc aagcagttcg ggctgtacga
     6001 caacacctac gacatcggca ccaactctgc cgagggtcac aactggctga tgcagagcga
     6061 caatccggag tacaccgagt cctcggccgg tgagtaccag cgcagctacg acaccgagaa
     6121 cgacgcgctc ggccaccaga agtccggttt cctgtggacc ggtgcgcagg ctgcgggcag
     6181 gtccgtcaag gacttcggtg agttccagtc ggtggagagc aagccgtccg gagcgtcctg
     6241 gcagaacctg tactgcgacg ccaggaccat ggacgcaacc gggaagccca cggcctaccc
     6301 catcaagacc gggtcggcga tcccctcgct caacgacgtg tcggtgcccg gctttccgat
     6361 gttcgacctc gacgtcccgg acgtctacaa gtaccaggtc tggaagcagg acttcgagaa
     6421 gaacgggccg gcgaacctga acatgctctg gttctccaac gaccacaccg gtggtcccgc
     6481 gagcccgtcc gcccaggtcg cggacaacga cctcgcggtc ggcaagatgg tcgacaagat
     6541 ctcgcacagc aagtactgga aggactcggc catcttcgtc gtcgaggacg actcccaggc
     6601 cggcctcgac cacgtggacg ggcaccgggc cccgatccag atcatcagcc cctgggcgca
     6661 gcacggcagg accgacagcc actactacac ccagatcacg atgatccgga ccatcgagca
     6721 gatcctcggg atccacccga tgaatcagaa ggacagcgcg gccagcccca tgagcggcgc
     6781 cttcaccgcc tacccggaca ccgccccgtt caaggcacag cccaaccgcg tccccctcac
     6841 cgacggtctg aagacccagc cgccctgcgg ctcggacaac ccggcagcgc agagccccag
     6901 ggcagcggcc gtctcgcccg cgacggtacc cgcggacaag caggacctgg cggcaacctg
     6961 ggacacgtgg aagtccaagc agcggctgac cggcccccac gccgtccccg actacgccaa
     7021 ccccgcccag atgaaccacc tcacctggta cgagacccac aactggaaca ggccgtaccc
     7081 gggcgagaac aagatcttcg cgccacagga tgtgccgggc gcgtaccttc cgtcctcgga
     7141 gaacgacggc tgacgtctgc tggaagctga ggggcgagtg gctccaccac ggcccgacgg
     7201 ccacgccgtc gggccgtctt cggcttcccc cacggaagct ccacctctac cggcgggaac
     7261 gctgccacgt gacgcttcaa ctccggagcg gaccgcgtag cggaccttcc agttgggtgt
     7321 ctgtccagtt gggtgtctgt tgctcggtgc gggcgcgggc ttgcaggtcg cggagttctc
     7381 gcgagggaag cccacgttcc gggcgctctc acgggagttg gtgcaccgag gcggtccgga
     7441 gacggttggc gctggccctt ggtgaaccgc gccacgatca gcggggcggc cgtgggtccg
     7501 gaggcggtga cgtgcgcggc gaatcccttc cagttgctgg tgtgcccgtg gcacacatag
     7561 cgtgccgtgg cgtcgtaggg ggagacgatc gccgtggcgg agggcggcag gccgacgccg
     7621 tcggcggtgc gccagcgcag gcggcctgcc gcgtcgcggt actagggcgt ttctgacgga
     7681 tatccgtgga ggaaggagca caagcacaag caccccgagc gcgagcctcg gcgtcggcgc
     7741 cgggcgacgg gcgacgggcg agcaacgtcg agatcgtcta caccccggcc aactcctcct
     7801 ggctccaccg tatcgaggcg ccatgccgac ggccgccgcc tccgggccgt cgtcgccaag
     7861 gccaacgtgg cctgatacga ggtcagtcgg cctgcaggac gaagaacagg aagcacacga
     7921 aggcccccga gggcttgtcc acgaagatgt cggggaacaa ctcgcgggcg cccggtgcgg
     7981 gaagcggttc gctgatgacg ttgatccgga agccggccgc ggtgaaggct tcggtcatcg
     8041 cgtgcagcgg ccgatgccag aaggtcatca gggcggtgtg cccacccagg gtccattcct
     8101 cggagtgctt gtacgtcgcg aagtagtcga tgcccggctg cacgaggccg atggaggggt
     8161 gatcaacgga cacgatcagc cggccgccgg gagtcagcac gcgccgcagt tcggccagcg
     8221 gtgccgtcca gtcctccaga tagtgcagga ccagggacgc gacgacgtcg tcgaacgcgg
     8281 cgtcggggaa cggcagcggg ctgcccagat cggcgaggtg cagggccgcg tcgtcgccga
     8341 gccgcttcct ggccagctcc agcatcttgg tgctggagtc gaagccggtc acgatcgcgc
     8401 cccggtcgcg cagcgccgcg gacagggggc cggagccgca gccggcatcc aggatccgtc
     8461 ggccggccac gtccccggcc aggtccagca tcgcaggccg ctcgtagtgc gcgttgaaga
     8521 ggctcgtttc gttctgggtc gagtacgcct cggcgaagct gtcgtagtcg ttgggcgcag
     8581 cctgctcccc gggcccggcg gaaccctccg ggacaggacg gatccacggc ggctgcgagg
     8641 gtgccgggat gcctgcgtgc acgtcagacc ttctggaagc ggaagtcata cggtcgatcc
     8701 tggcacgcac gtcccatctg gcgtcgggag attcacgatc cccctgcttc ccatcgaagc
     8761 cgatgagcgc catacagggc gtacgttgtc tgatgcggca ctaggcgaac caggatggtg
     8821 ccgagacaag cacccaaagc caccagaaag aacagtccgg gcctgaagcg cgaccgaatc
     8881 gccccgccga cgcataggga tcaggccgga cgcgtccgtc accgcatcgc ccgcgcggcg
     8941 ggagagggtg tgggccagcg cgcggagatc catgacccac tgcatagctg cgtaggtggg
     9001 atctgatcag atcggatctg atcagatcgg atctgacagc acatatcgat ggttttcggc
     9061 ttcagccgat gcccgacaga agtcgggatg tcggtgagca gaagcagcgg cccgcacctg
     9121 gctcaggggc gaacggcgcg gacatggccg gccgagagat ggagctcgta cggcaggcag
     9181 cagtcggagg agagggtcgc gacgaggctt ccgcaggcgc acatctggtt cattccaccg
     9241 tccggggtcg ctccacagca ggcggcggac gcgtgctgaa gcttcaggcc gcgggcatcg
     9301 tccgggttga tgacgatgtt gcctcgcggg ccctgcgata ccaacggttg cccgtgcacg
     9361 ttgctcatca ttccgcggcg tggcatcgca ggcccaggca cctcggcgac gaccaagggc
     9421 gcaccgtacg gttccgcctc gaccgcatag tgacgtgatg gcacggtcgg gggtgacgga
     9481 cccggttcat cggcgtccca ccatgcggtg tacggagcct cgggaactgc gggcagcctt
     9541 gtgagaggcc ccgtcaaggg gactccacag gccgcgcaca cgaagaccac cgcttcgcac
     9601 tccgtagcgg cgtcggtgag gtcagcaggc agggcggcct gcctgggctc cggcctgcta
     9661 ttgccttgct cttgctcttg ctcttgctct tgctcttgcc gatcgtgcat gagctgaccg
     9721 tatgtggcgc gccgcgaggg cctgcggccc ccctccagag caacgcacga catccgtggg
     9781 gctcgcggtc ggtgtccgtc gcctgtccaa ccgcaagagc ccccaccctc cgtcgcctca
     9841 gcccatcctg ccggcggaga cgttcatcga gcaggcagac ggacagatag cgtcaggtat
     9901 tcgtgcctga gctgcgacga ccgcgcccag gtcgtggtcg gtgccgcgat cggcggatgg
     9961 gacttcacca cgctcaccca gcgccgaacc gcacggaaga tcactgggcg cgcagcacgc
    10021 cccacagcgg cagctgttcg aagaactcga cggcttcgtc ccgccaccgc ccccgccagt
    10081 tggccgcgac ggcggccgcc tcctgggcac agcggcggat ctcggcgagc agctcgttgt
    10141 cgacgccgtg gcgccgggcg atgtcctgaa tccgttcgac ggtctgcggc ggacagccgg
    10201 ggccggcgag cgccgactcc acgaccgccc gctccgcacc gctcgtcgct gccagcagcg
    10261 cgcacaccgc gtagctgcgt cggccctcgc gaagatccga tccggctggc ttgccgaccg
    10321 tgcctgcgtc cgcgaacagg tcgaggtagt cgtcgcgcat ctgcccgctc acgccgagca
    10381 gtcgtgcgta ccgggccagt tcgttctcat gggccgccgg gtccgcgccc gccgcgagca
    10441 gacccagctg caacggggcc agcaccgagt accgggcgct cttgtactcg gacacggtgt
    10501 ccagcacctc gcggtcgggc accgggccga agtcacgctc cagatcgagg aattgcccgc
    10561 ggaccgtgtc cgccccggcc gtcgcctgta cggccgccat cgcctgccgc agctcgcggg
    10621 gaaccggcgc ggtcagcagc acctggaccg acagaaacgc ggccaggtcc ccggccagga
    10681 cggccagacc caacgccgtc tgcggacggt cagggaaccg ctcgcggtag gcgtagtaca
    10741 ccgacggcgc cccccggcgt accggggagt cgtcgatgat gtcgtcgtgg atcagcccgt
    10801 gcgtctgcag caactcaatg ctgagcgcgg cctcgtccag cccgggcacg gcatcgggag
    10861 ccaccaggcg cgccgcctcg tacagcagcg cgacccgtag ccgcttcccg ccccgcagcg
    10921 acatgtcccg caccagttcc agcgcctcgg gcacgaacga attgcgcggc ggcccctgct
    10981 cggcgaccga gtcgaagtag ttcgcgaaca ccccgttgaa gcggtcccgg tatccggcga
    11041 gccgctcgtg tacaccggcc gcgttgtcag cagtcattgc tctccctgga accccgtcaa
    11101 acaggacggc cgtcgacaga caccgccaac tcgcattcaa caccaccaga tcaactccgc
    11161 gtagcgacca gggcgatcgt gcgggagccg tgattgcgcc ccaaccgcgc agacgctgcc
    11221 gggcacctcg aattcttgag ggtgtctggc agtgcctgat cgagccacca cccaactacc
    11281 gaggggacag ccgtcccacc acgcgccgcc tcaggtgatc catttgccgg tcggtctcag
    11341 cgtccgagtg ggcccgtgag cgaccgagtc ggcccgagtg agcgtcaggg ttggcgcgtc
    11401 gcgaccggct ggagctcctg ccatgccggg tagtgggtgt agcccgcggc gccgtgaccg
    11461 tacagcgctg attggtcgat gtgcgtgttc agcggcagac tggctgcgaa gcggtgcggc
    11521 aggtcggggt tgctgatgaa caggcgcccg tacgagacca ggtccgcgcg ccccgatgcg
    11581 agcaccgcct caccggcctc gcgggtggtc ggggcgtggt tctcgccgac gttggcgatg
    11641 agtgtgccgt gccagcgcgg gcgcaggtcg gcgagggcgg ggtagcggtc gtcgtcggtg
    11701 aggtggaggt aggccaggcc gaggccgtcg aggcgggcga ggagcgcgcg atagaccggg
    11761 gccgggtcgg cctcttccat accgaactgg gggttacccg gcgagaggcg caggccgagc
    11821 cggccggcgc cgaccgcgtc cgcgatggcc tgtaccagtt ccagcgggaa gcggatgcgg
    11881 ccggagatgt cgccgccgta ggcgtcggtg cgcaggttgg tgttgtcggc caggaactgg
    11941 tggatgaggt agctgttcgc gccgtgcagt tcgacgccgt cgaagccggc ccggatcgcg
    12001 ttgcgggcgg cggcgacgtg gtcggcgatg gccgtgcgga tgtcgtcgtg cgtcatcgca
    12061 cgcggtatga ccgggtctgc cttgccgtcc ctcacgtgca cgggcccggg cacggggacg
    12121 gcagagggac cggccgggat gtcgccgagg atacgggagc gtgggtgccc ttgacggccg
    12181 ccgtgcatca gctgggcgaa gatccggccg ccggcgtcgt gcactgcctc ggtgacgtgc
    12241 tgccaggcag acacgtgtcg ttcggactcc aggcccggga tgcgccagcc gctctggccg
    12301 cggaggctgg gccagatgcc ctcggtgacg atgaggccgg cgccggccct ctggcggtag
    12361 tagtcggcga cgatcggtag cggggtgccg tcctcttcgg cgcggaagcg cgtcatgggg
    12421 gccatcacga tgcggttgga gagggtcagt tccgctgagg tgaagggcgt caggagcttc
    12481 atcatgcgca aaccgtagaa tctgacactg atgtcaagtt caagtcctcg aggggagatg
    12541 cgtgatgcgg atcggtgaat tggcccgccg caccggcgtg agcgagcgtt cgctgcgcta
    12601 ctacgaacag cagggattgc tcgcgtccga gcggacgccc ggcggccacc gggactatcc
    12661 ggagcgcgcc gtggaccggg tcatccgcat ccaggagctg ttcgccgccg gcctgtgcag
    12721 caagaagatc gcccaactgc tgccctgcat acgtgaccac gacggcggcc cagcggtcac
    12781 cgccacaccg tggctggtgc aggaactgcg ggctgaacgc gagcgcatca atcgcaccat
    12841 cgcggacctg cgccgctcgc aagccaccct cgacgaggtc atcgacgccg cctcgcgccc
    12901 atgacatcgg tgatcgacgg ccccgtgggc gccccctcgc ctcggcgata gcggcccatc
    12961 caacagacaa aaggcggacc cttgtggatg gtgcgcaagc ggcagtctcg ggccgcttcc
    13021 ggagccgcgt catacgtaac ggggcagtga tggagagctg gttcgtgctc caactgaccg
    13081 ttttggacgg cgagatcacc cgctaccgct tctacgagga cagccttact gtcgcccgcg
    13141 catgggctac gacgaccgca ggggccgacg gtcaggtcca ggaggcccat ggtgggacga
    13201 ccggctgacg cagcacatca gcgtcgacgg tcaaccaatc ggctctgccc acagttccgt
    13261 gaatccccag gtcagaggcg gtgtcgacag gatctgctcg ccgcgccctc gccgagctgc
    13321 gcgaagcctg ggttcgccga gataacaggc tgaacgacct cgaatgtgcc aagcagtgct
    13381 ctttgcgagg cggcttttcc cgagctcagg tgggctgcga cggcagccag ccgtgctgca
    13441 cggctcgcgc gcccgccgcg aagcggctgc gggcgccgag gcgttccatc aggtcggtcg
    13501 cgatgcgtcg cgccgtgcgc tgggagaccc ccaggcgttt ggcgatggcc tcgtccgtgt
    13561 ggccctgtgc cagcagggcg atggtggtgg actcttgtgg gttcagcccg tgggagttcc
    13621 tgggggcggc ctcgccgagt ggctgagcgc aggaccagac gccctcgaag agggcgcaca
    13681 gtgcggtgag cgtgccctgg ctggtgagga cgacagcgcc cgtggcggtg tcctcgctgc
    13741 tgacggggat gaccgcggtg gagccgtcag tgatgatcat tcgggtgggc agggccgggg
    13801 tggtacggat ctgaccgccc aggtccgtga gccagttggc atagtcgacg gtgggctggt
    13861 cgttgcggac gctgctgagg tagacggtgc gtatccgcac cccccgcccc agcaactgct
    13921 cgtccagcgg gcgcgacgcc ttcatctggg ccgcgggctg ggcgccgccc ggggcgaacg
    13981 acatgacgtc ggtggtcaca tcgcgggtga gcctggcgag gcggtcccgg atctgttcga
    14041 taccgatgag ctgctcgacg ccggggctgg aggcggccgg gcgcagatcc gcgtattcgg
    14101 cgatcagctg cgcggcgacg gcgcgcgagg tctccaggcg ctgctgttgt gcggccaggt
    14161 ccgcctgttg gcgggccatc aggatctcca tgccgatctc cggcgagacc gccctcggcc
    14221 ttcctggctg ctcgatcgac ggccgcacca aggccagctc gctgagcagg tcgagggcat
    14281 cgcgcacctc gtcctcgggc ttgcccaccc tggcgacgag ctcggcgacc ccgcccagcg
    14341 gatcggccag catcgcgcgg tagacggact ccgcgactac gtcgagtccc aatgcggtca
    14401 gcaacgcaca tccccctcat tcatgcacaa ctccacccct ggattcgtgt ggatcatgcc
    14461 atacagggcc gatagctgta tgtccggcat aaggaaatag tgccgcactg gaccgaagtg
    14521 tccatggacg gaagcgtcca cattccgctc ctggcaggcg agttgtcggt ttgggagagt
    14581 cgggtcatgt atctcgtcca cgcccgcctg cagggaccgc ccggcgcttt cctcccgctt
    14641 gagacgcggt ccttggtccg ttcccagacc catgacggcg acggcgtcga gcacgtcacc
    14701 gtccacccgg atgctctgcc ccacccggtg gtcggtctct acgtacgcgc cgacagcctt
    14761 gccgccgcgg aataccgggc ggcccgggtc tgccggctgc tgctgggctg cgccgggttc
    14821 gacggctggt cgctgccggt cgtcgaggcg ccgatggtcg cacccttcta cgagtcgcgg
    14881 ttatccgacc cggggcccgc cggtccggcg gtggacggat gcggccaagg ccattttggt
    14941 ccagccgaaa acccttccac cccctctgac cagcagcgaa agtagttctt gccagcaggg
    15001 aacaccgccc ggcgggcaac ggaccggaca gcatcaccgc gggatgcgaa ccggtcgagg
    15061 acaccaacac aacgtcagaa gagggctttc cccatgcttc gtctccgtct cgccacggcc
    15121 gccgcggtcg ccaccatcgc cgcctcggcc gcgaccgccg cccccgggca gaccatgggc
    15181 tggtcgtagc ccccggcttc ggctccatca cccggaccgc tcccagccgc tccgtagggc
    15241 agctgcagcg gcccggtgtc ccggccgcac atgctgcgca acacccgcag taccgagccg
    15301 caccgggtag gcccggcagc tgcccgtgcc gcccgtcact gcatcccgca tcgccactat
    15361 tgaggttccg ccatgcccga aacaccccgc gccacgtccc gtacggcctg gaagtccgcc
    15421 gccacggccg ccctgaccct cgcaggtctc accctctccc tcgtctccgt tgcccccgcg
    15481 accgctgcct cgctcggcac gtgggacaag gtcgcccagt gcgagtccag cgggaactgg
    15541 cagatcaaca ccggcaacgg ctactacggc ggtgtgcaga tctacctgcc gacgtggaac
    15601 gcctacggcg gtcgcgagta cgccacttac ccgcaccagg ccaccaagca gcagcagatc
    15661 ctgatagccg agaagatcct cgccgggcag ggtgccggcg cctggggaag ttgcggggcg
    15721 ggcgccggcc ttggcggtga ccacgccgac ccctacccca ccaccccgcc cgcgccggtc
    15781 ggcatggtcc acctgacggc cgcggacttc accggtgatg gcaggaagga cctggtcggc
    15841 gtcgaatcgg ccaccggaaa gctgtggctc taccccggca agggcgacgg taccttcggc
    15901 gaccgcgtcc agatcggtac cggctggaac accatgagca agctcgccgc cgccgactac
    15961 accggcgacg gcaaagccga cctcctcgcc gtcgagaact ccaccgggaa cctcttcctc
    16021 tacccgggca ccggtagcgc ggtcggcatg aacaccctgg gtgcccggac ccagatcggc
    16081 tccggctggg gcggcatgcg ggacctcacc gcgatcgacg tgaacaagga cggcaagccg
    16141 gatctggttg ccgtggacac caacggcagc ctgtgggcct acccgggtac cgggtccctg
    16201 gcgggcagca gcaccctggg cggccgcgtc cagatcggct ccggctgggg cagcatggcc
    16261 gagctggcga gccccggcga cctcgactcg gacggcaagg ccgacctcgt cgccgtcgac
    16321 ccggccggcg cgctgtggaa gtaccccggc accggcgccc tcaacggcag caacaccttc
    16381 ggggcccgca accagatcgg ttccggctgg aacagcatgc accagttggt cggcgccgac
    16441 ttcaacaacg acggcaaggg cgatctggac gccgtccagg cacaggccgg ttccaccggc
    16501 ggcctctact tctaccccgg caacggcagc ggcggcctcg ccgaccgcgc ccggatcggc
    16561 accggctggt agccgcgcca cccgccgcga cttcgctacg ccttcaccgc tcgcgcagca
    16621 gtccgccgcg cccgcttccg gactttcacg ctttcagatt tcaggagacc cttcatgtcc
    16681 acgttcgcag ccaagttgaa gaagaccagc gtcgccaccc tggtcgtcgc cgccgcggtc
    16741 accggtctgg gcatcgccgg accggccgct gccccggccc acgcggccgg cacctccgcc
    16801 gtcgggggcg agatcaccac cgcagaggtc atgtcccgtg cccagtactg ggtcgaccgc
    16861 gccgttccgt acagccagtc ggactacgac ccggacccgc agggccgcaa ttaccgccag
    16921 gactgctccg ggttcgtctc gatggcctgg cacctgaaca ccagcctcac cacctggacg
    16981 ctgccgcagg tcgccacccg actgtccagc ctggacgagc tgcagcccgg cgacatgctc
    17041 gacaacatag actcccacgt cgtgctcttc ggcggctggg ccgactcggg ccgcaccacg
    17101 gcgaaggtct gggaagaggc ccacccgggc accaccgccc gcgtcaactc gtcctattac
    17161 acccgcagtt acatcaacag ccacggcttc cgcccctacc gctacaccaa gatcgtggag
    17221 tccaagccga ctccgaagga cgtcggcatg accaacctca ccggcggcga cttcggcggt
    17281 gacggcaagg ccgacgtggt cgcggtcgaa gcgtccagcg gcaagctgtt ctactacccc
    17341 ggcatcggcg gcggccggct cggcgaccgc gtccaggccg gcaccggctg gaacacgatg
    17401 agcgagctga cctccggcta cttcaccggc tcgggcaagc tggacctcgc ggccgtcgac
    17461 aacgacggag tgctgtggat ctacccgggc aacggcaacg gcaccttcgg caaccgcatc
    17521 aaggcgggca ccggttggga cggcatgcac gacctggcgg gcgccgacct caacaaggac
    17581 ggcaagagcg acctggtggc cgtcgagtcc tccaccggca agctctacgc ctacccgggc
    17641 aacggcaacg gcaccttcgg caaccgcgtg cagatcggct ccggctggaa cggcatggac
    17701 cagatcgtca gccccggcga catgaacaag gacggcaacg ccgacatcgt ggcccgtgag
    17761 gtctccaccg gcaacctgta cgtctacccg ggcaccggct ccttcaacgg caccaacacc
    17821 ctcggctccc gtacccagat cggctccggc tgggactcga tgaccaacct ggtcagcggc
    17881 gacttcaacg gtgacggcat cggcgacgtg gacgccgtcc aggccaaggt cggcgagacc
    17941 ggcaccttct acagctaccc gggcaccggc gccatcaacg gcaccaacac cctgggcgcc
    18001 cgcgtccaga tcggcaccgg ctggtaatcc cgccgcaagg cccccgaccg ccgctctccg
    18061 aagggccgcc accgcaccca cacaccgcgg tggcggcccc gcctgctccc cgccgctctc
    18121 cgggaaccga cccggccgat gaaaggacca gtgccgccat ggcacgccga cacctcctcc
    18181 gcaggacccg cacccgaggg cgaggcgccg cggtggcggg cgtgatggcg ctcgcctccc
    18241 tggccaccgg cagccacgcc gtcgccggga ccgctcccga cgggaccacc gccacctaca
    18301 acagcatcac ccggacaggc accgacggaa tggggctgca atcggacaac ggccgtgagg
    18361 cgcgccgggt ctccgccttc gcatccgccc accccgcact gggacgggtc acaacagccg
    18421 atgtcctcgc cgacacctcc ggcgccggcg cgggccgcac tctctgccac cccaccaaca
    18481 tcgcgggcgc ccagggcttc tgctggtccg ccgcggacga caacaccggc tcctggatcc
    18541 cgcaagggct caccggctct ggtgaatccc ctcggtcaca ggccctggtc aacggccgca
    18601 aggtgctcat caccagttgg tacggcgctt ccggaaccga gcgggtcacc ctcgccgatg
    18661 tgacggaccc ggctcatgtc acctaccggc acgtccagtt ggccgccctc gacgacacag
    18721 gcgacaactt cgtcccgatc accggcggac acgcccacgc ggtggtctgg gccggcagca
    18781 agctgtacgt ggcgagcacc ggcagccgct tcgacgtctt cgacctgaac gagatctgga
    18841 agatggacgt caccaccgac acctcgttcg gcatggacgc gaagggcaag gcccacggcg
    18901 cgggccaccg ctacgtcctg ccacgcgtcg gcacctacgc cttcacgggc cagggcacgg
    18961 gctgcggctc gtatgccggt gtcccgcagc gcccctgcat caccgcggcc tcgctcgacc
    19021 tcagcggttc ccagcccgcc ctggtcaccg ccgagggcga tccgggcggt gtcgaggggc
    19081 agttcggcaa ggccaccgct cccgtcgtcc gctggcccat cgacccggtc accggcgtcc
    19141 tcaaggccga cgccggcggg cgcgtgcgcg cccatgaagc cttcgcgtcc ccgatgggcg
    19201 gtacgcaagg catcgccatg aacaacggcc ggttcgtcct ctcgggcccc tgcccggagt
    19261 tcgtgcccgc cgagcaccag ccggacccgg agcacatccg gaatttcccg ggctgcctct
    19321 accacgcccg gccgggcgag cccgtacgcc tggtgaccag gacccccacc aatccggaga
    19381 acctctccta ctggcccggc accgaccaac tctggacggt caacgagtcc accggcgaac
    19441 gcgtcgtcgt caacacgccc tggcccaagg accccgcgcc ggtcggcatg gtccacctga
    19501 cggccgcgga cttcaccggt gacggcagga aggacctggt cggcgtcgaa tcggccaccg
    19561 gaaagctgtg gctctacccc ggcaagggcg acggtacctt cggcgaccgc gtccagatcg
    19621 gtaccggctg gaacaccatg agcaaactcg ccgccgccga ctacaccggc gacggcaaag
    19681 ccgacctcct cgccgtggac tcggccaccg gcgacctcta cgtgtactcg ggcaccggca
    19741 cggcgaacgg catgaacacc ctcggtgccc ggacccggat cggcaccggc tggaacagca
    19801 tgcgcgagct gaccgccatc gacatcaacg acgacggcag ggccgacctc ctggccgtcg
    19861 acaccgacgg cgcgctctgg gcctacccgg gcgccgggtc tctcgcagac ggcaacaccc
    19921 tcggcaaccg tgtccggatc ggtaccggct gggacaccat gaccgaactc accagccccg
    19981 gcgacctgaa cgccgacggc agggccgacc tcgtcgcggt ggaccgctcc ggtgccctct
    20041 gggcgtatcc gggcacgggc tccctcaacg cgagcgacac cctcggcagc cgaacccgga
    20101 tcggtaccgg ctgggacacc atgcgccagc tggtcggcgc cgacttcgac aatgacggca
    20161 agggcgacct cgaagccgtc caggcccccg ccggctccac cggagccctg tacttctacc
    20221 cgggcacggg caacacggcc ctggggagcc gcacccagac gggcacgggg tggtagtcgc
    20281 tgcgtcggcc atgggggatg gcgctgttac gtatccgcat ctggcgcgta cgtgacccgg
    20341 ctggacttga ccgatgggac tgcgcggctc cgcgtgtgca gtttcggggg agtatcggca
    20401 atatgtccgt taggcggcct gccgtcgagc gcgtgcgcgt ctccgcggaa cgcgacccgg
    20461 cctcggagac tttggtccct cggctcggtg ttgccggcca gcaacaccga gccgaggcac
    20521 ccgtcgccca cgtaccggcg gctcatcctg ccgggttcgg acttcaaagg cccgcaggga
    20581 ctcgccctgg gcgtcgcggc agtgcgctgg ggtcagttgc gcaccaggta ccagtcgctg
    20641 tcctgcatgc gcggaacgtt cgggtgcagg tagccgacca ctccattgtt ctcgtggtcg
    20701 caatgccgat tcctgaactc cgtgatgtcc atcctgccga cccaccagtt gtcacggatg
    20761 taggtgtccg tcgctggtgt catccagcag aactgcacgg gcttaccgtt ctggttcttc
    20821 ccgtccagcc agatcgacgc caccttgtgc cgcctgtcct ggaaatggat ctgctgaccg
    20881 ctgttcccgg cgaaagccac gccggccccg agcgttaacg aaccggccag tgcggccgta
    20941 caggccgtgg ccatcgccat cctgcgcaga cgaagcatca tgtttgcctt ccgttgcctt
    21001 cctgcggagc cctcgtgacg ccgtcgcgaa cgtgcggtcc gtcggaccgt ggcggatagg
    21061 cggctggtga catcagc
//
