LOCUS       NZ_LJSN01000003        21888 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces noursei strain JCM 4701 scaffold3, whole genome shotgun
            sequence.
ACCESSION   NZ_LJSN01000003
VERSION     NZ_LJSN01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
REFERENCE   2  (bases 1 to 3830602)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method :: SPAdes v. 3.6; SMRT Analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891315.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 20:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,947
            CDSs (total)                      :: 8,851
            Genes (coding)                    :: 8,489
            CDSs (with protein)               :: 8,489
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 362
            CDSs (without protein)            :: 362
            Pseudo Genes (ambiguous residues) :: 0 of 362
            Pseudo Genes (frameshifted)       :: 118 of 362
            Pseudo Genes (incomplete)         :: 301 of 362
            Pseudo Genes (internal stop)      :: 23 of 362
            Pseudo Genes (multiple problems)  :: 74 of 362
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 104483
            Orig. end                         :: 126371
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJSN01000003.1.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: http://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21888
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21888
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21888
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11888](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11888
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(859..1785)
                     /locus_tag="AOB60_RS22320"
     CDS             complement(859..1785)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013227.4"
                     /locus_tag="AOB60_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_102924729.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.8e-33,
                     bitscore: 113.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTDPAVAAAVQDLLHRWGQPAAEFCASGGTALEAALEVLEVDA
                     GAEVVVPDVGCHSVAAAVVRAGAVPVFVGVGEDLTLHRDDVAAACSARTRAVIAVHQYG
                     LPCDVTGIAQALPPDVAVIEDVAQTWGSTTRGVPAGATGTLTVASFGPSKPVSLGAGGA
                     LLGPADLVSGAVARGDTTDRHRPRPPSPARFPAPLLPLLPDAIARADRQLARRRAVVDR
                     FRDSDLARHFRLPPLPPGSSAGWTRLPLYPAPSATARHIGQLADDLGPVQPMHPQPPSA
                     LPMFHRCEKRVLTGGRRAVEPLLVKIG"
     gene            complement(1772..2890)
                     /locus_tag="AOB60_RS48515"
                     /old_locus_tag="AOB60_21475"
     CDS             complement(1772..2890)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024871.4"
                     /locus_tag="AOB60_RS48515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21475"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_102924730.1"
                     /transl_table=11
                     /translation="MTATGRPAEPDLDTRRRSADPAAPHPLPGGRAVPEPEPAHDLRLV
                     DLDALPGAQEDAWARAYRRHGTRLQQSPGYAHAVRAAGHRVVVALAPDGIAAFTRDGDV
                     LTAVGDDEPLLTEHGHPERLARLVTSVRRATGASVYLPLVAAPHAEACARAGCTTWRRP
                     PNSLIDWSHDGADLWERALERGSSQLRRKRHLVERDGLTVRPGRSGPLAFADVLAVDDR
                     SWKAARGQSMRQRGGQDALYGRLVDTGEITAAFLLDGERPVAFRLDARVQDRLMSLKWS
                     YDETYRRYSPGLYLLTEGLRQEWAGRGVRTVDLHGSPDALKNLLHTERVPRADVWCGAA
                     EPGALRARERAALDARVAGAHEAGKGLRHAFD"
     gene            complement(2887..3798)
                     /locus_tag="AOB60_RS22330"
                     /old_locus_tag="AOB60_21480"
     CDS             complement(2887..3798)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_21480"
                     /product="hypothetical protein"
                     /protein_id="WP_102924731.1"
                     /transl_table=11
                     /translation="MDSDTVSPDELAKVVAGLPVQVWNSPTAAELYGHTLNLVCRTRAG
                     RTAGVWVVPLDDGGTAARRPFRLLPYAAPWSDPGLHPVDRHRAVHSMTQALMARVDSAE
                     LPMDPRFGEVAALSEAGAELLCRHTRILELREGRDPRTAYVATARNHIRAAARRHTVHN
                     APLDSFDFSRAVVGQPAPAVAARRRSGLRIGREEPALCLAATDPDGVCRGQVFVLLCDG
                     AAVLMHSWFDRTGARGVPSLLVDEAITWAQRQPGTEVFDFEGSVLPSIDRFMTGFGAHA
                     RGYPQLRWIRSGRPGSDAGEFG"
     gene            complement(3853..4662)
                     /locus_tag="AOB60_RS22335"
                     /old_locus_tag="AOB60_21485"
     CDS             complement(3853..4662)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="AOB60_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21485"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_102924732.1"
                     /transl_table=11
                     /translation="MANLALYGLGEMGADIARCLVARGVELHAYDPVADVAPEADHFHR
                     CATAAEAARAATVHLVVVKRPDDVRTLLFGADGLCAAAPPGSHVVLHTTLTPQTVRELA
                     DAVREQGHILLDAALSRRDGLVRDGSLSLFVGGSAAELGTVWPVLERYADNVVHAGPTG
                     AGMTVKLCNNWLLYSNRHAALQALRTGRALGVDPDVLRGALATSTGSSWALAHYSDLDE
                     AIVTGQGAPAVVRDRTTSELHMARDMAATSGQVPTSLQETFALLDAM"
     gene            complement(4737..5975)
                     /locus_tag="AOB60_RS22340"
                     /old_locus_tag="AOB60_21490"
     CDS             complement(4737..5975)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="AOB60_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21490"
                     /product="MFS transporter"
                     /protein_id="WP_180990241.1"
                     /transl_table=11
                     /translation="MSTLQSQSTSALLLLLLSLLALRVTGSPASAPLVVAVGALPALLL
                     VRVVRIVNQRVDHRWVMLLSDTGAFAVAVTLWLLVRGGGVHAWQIYAGMFLFASFGAFY
                     LPAMRGWVAGQTTGLEQLTWLNAMLAVATQASVVVGWALGGVLASSIGIQASLGLCALS
                     YAVGLVLQFVVFVVINRAPLHKSAVAAGSAGPGAAEPDTGGEGRPSAAGVWREVFAPRR
                     LGLFTAALLLMELAHTLGFSMFVPLLTGGASDRSWIAGTANACFALAAMISGVLVSGGT
                     LGRWTRARVPQIVLAGFCVQIVFGLSAAHPVWAICLYAVVGLLSGGDAALQSEVQDRWR
                     PAGSAQAFAVFGAVQGPSQLVGSLLVAALLTCLSVGTVYLGTIVVLGLGSGLALVLARS
                     RAAAAAPRAEAPV"
     misc_feature    complement(6306..6319)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.36"
                     /tool="antismash"
     gene            6979..7698
                     /locus_tag="AOB60_RS22345"
     CDS             6979..7698
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025033.4"
                     /locus_tag="AOB60_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_102924734.1"
                     /transl_table=11
                     /translation="MTPAQWEALLYDWHNAHRLRRQRNDTAYWARLTEQHDTVLVLGAG
                     TGRVASTLAHPARRRVTAVDLSRERLARMPRTPGLHPVCGDMRRLPLRGSHATAVIPYS
                     TLQLLVTPHDRQRALTEAARVLAPGGSVHIDVSESFDARTETDWQIGLAEPCREAGGPV
                     EEWERHRLHADHVVIEKQFRRSGRVLTEVTERWAFHSALNLAEALAQAGFELVGIDRGY
                     GADLSPHRLIYHGRRTH"
     misc_feature    complement(7872..7890)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.42"
                     /tool="antismash"
     gene            7896..8288
                     /locus_tag="AOB60_RS22350"
                     /old_locus_tag="AOB60_21500"
     CDS             7896..8288
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025887.4"
                     /locus_tag="AOB60_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21500"
                     /product="DUF4440 domain-containing protein"
                     /protein_id="WP_102924735.1"
                     /transl_table=11
                     /translation="MEPDRVTDERLHGVLAELMRREPLFHRPEFGTSRADFEAMTAPDF
                     WETGASGQRYSRAYVLDVLEERSQEPPVEEWETSEFHCRELAADLYLLTYTLVLNGWRT
                     RRSTIWQQASDGWRIVYHQGTPVLDA"
     gene            8545..9135
                     /locus_tag="AOB60_RS22355"
                     /old_locus_tag="AOB60_21505"
     CDS             8545..9135
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324511.1"
                     /locus_tag="AOB60_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_102926281.1"
                     /transl_table=11
                     /translation="MHHAYGRRVVLRGINISLRRGVVAGIVGENGAGKSTLLKILAGEV
                     RPQRGVVVHRGRFGYCPQDVVLNDALTVRQHLKFFMTAFGLPDLCRAEGLMEVLRFSEY
                     ADERAGVLSGGTRQKLNLTLALMHDPQVLLLDEPYQGFDWDTYRRFWDLAVGLREAGRS
                     VLVVSHLAYDTSRLDELWYLEGGVLRPRAEAAA"
     gene            9132..9947
                     /locus_tag="AOB60_RS22360"
                     /old_locus_tag="AOB60_21510"
     CDS             9132..9947
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046016.1"
                     /locus_tag="AOB60_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21510"
                     /product="hypothetical protein"
                     /protein_id="WP_102924736.1"
                     /transl_table=11
                     /translation="MRRHLTFFVTAARYDLVVHARNRFAMFLVVLYVPAWVTLAHAALP
                     DKPAPIRLNSTGEFLSPPGDQLSQITGALNAVTLIAGFMMFAATFNGGRFDRRLAMAGH
                     PRIHLALAKTTSLALACAAVSVYATAVTCAAWIPRQPALLATALFCDAMTYGALGVLFG
                     CVLRREVEGMFAMVMTSVIDVALQNPIANTGANSPLVRLLPSYGSMQAATGAGFTNGTM
                     TSCLAVQTLWFAGAALLALLAFHRRTRSAFPRTRRPRTPTRGRPAHGTR"
     gene            10001..10897
                     /locus_tag="AOB60_RS22365"
                     /old_locus_tag="AOB60_21515"
     CDS             10001..10897
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669513.1"
                     /locus_tag="AOB60_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21515"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_102924737.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.6e-31, bitscore:
                     105.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.2e-16,
                     bitscore: 57.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLRRWLDAAGIHDPVLRQCYTVCIRDIHKCDAGRAGWWALRAAP
                     AALRPHVAALVVHGYKADACADTGPVEERARRLDAYGTAALAAIESGSAADPVLHAMAH
                     TFRAFNLPRSLAEDMLAAMHHEIEMRQPATYAEWRHWATGIAGTPIVVLMLVLRSDRIG
                     PREPLVRELGELFQLTDVLCDLADDLTDRRLYLPADDLDRFGVRAQDLLAGHWTPATAE
                     LIAFEADRVRHRLPALVTALDDSPASSWADAMGRHCTLLLGLVRAAGADLLHRPVRPPV
                     SALFDVWQRQWRTVIPC"
     gene            10914..11888
                     /locus_tag="AOB60_RS22370"
                     /old_locus_tag="AOB60_21520"
     CDS             10914..11888
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669514.1"
                     /locus_tag="AOB60_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21520"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_102924738.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-51, bitscore:
                     173.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATASRPTDPLIPLIEAELIRSVGSGEDLLETACLDALFPGGKL
                     LRPTLCVESARAVGGRAESVLSFAAAIECLHVASLVHDDIVDQDPVRRGRASTAERFGI
                     AEALLAGDGLFTAGWAAMLRGGPADRVLAASRAIAEAVHAMCRASMREIEIREDLTCGR
                     SAVLEVIRGKTAALTGAACRAGAILADATPEQIDALHHYGEQLGMAFQIRDDLLPYTAA
                     DALTGKSAVSDVANRQPTLPVLLAYESADAHDRRHLTEIFHGNVDLATAHRDLLDVLAR
                     TGAIAEAARQARACAAQARAALGGLSATGRLAWLADSAADRHQ"
     gene            12087..12770
                     /locus_tag="AOB60_RS22375"
                     /old_locus_tag="AOB60_21525"
     CDS             12087..12770
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017959.4"
                     /locus_tag="AOB60_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21525"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_180990243.1"
                     /transl_table=11
                     /translation="MKSRIGYCAWIVGVGQFFAVHVVVESAWARPYSWARNNISDLGNA
                     LCAVQPDPEPRYICSPEHGLMNASFIALGVLLVVGVALAGGVVWRRGPLAAGSRLLLAG
                     AGVGFVLVGLAPADVNENQHVLGALLIMGTGNIGLLLAAFSLTDRLAGPLRWGTGLLGG
                     AAIAAFGLFLTEHYLGLGMGGMERVAVFPLLVWALAVGIHGLVRRPDRRPEAMSAQRLA
                     QPLRR"
     gene            12943..13113
                     /locus_tag="AOB60_RS22380"
     CDS             12943..13113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_180990244.1"
                     /transl_table=11
                     /translation="MSQELDEEVVRDRCLGFAPADPARPAALAERVREEDTPQEDVLLA
                     GMWGRALPGRS"
     gene            13161..13745
                     /locus_tag="AOB60_RS22385"
                     /old_locus_tag="AOB60_21530"
     CDS             13161..13745
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477582.1"
                     /locus_tag="AOB60_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21530"
                     /product="hypothetical protein"
                     /protein_id="WP_258018017.1"
                     /transl_table=11
                     /translation="MDDAFTLLRQVAELLPGDAAAECGMTVEDARDAIELQEWEMALDL
                     LIEIAEVHPVSLALWDTLAEAARQMMLDRSRRRCEWHGWEVRHGTVRAKLTLLGADEGG
                     RRSAFSGDGQLRPLWDIGGRAADGQREVRIARLWVECVQELGPGETADVRLAPLSPEQW
                     RHLKPGDVITMHEGRPAVGTATVIEVRPPRT"
     gene            complement(13908..14834)
                     /locus_tag="AOB60_RS22390"
                     /old_locus_tag="AOB60_21535"
     CDS             complement(13908..14834)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579355.1"
                     /locus_tag="AOB60_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21535"
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_102924740.1"
                     /transl_table=11
                     /translation="MTHVLVVGGTGAMGSHVIQHLLATTDATITVPTRHPESAHATELA
                     ATAPHRLRLVHSDPAALDALMGQADRVFANTDFFATGSAVGEYRQGLELLTAAERAGVE
                     RFVWSSLDSAVSLTGRPVPHFDSKAAVAAHIDLMRSEEMLRKETDGWYTNHVSVLTTAP
                     YFENLRDRLTPRPDGRGGLVFRLPLGAAHYPLVALDDIAWFACHLFDNWQSWGARDLAV
                     IGDSLTGDEIAATFTQVSGTPSSYLPMSHDELHAAVPDFGHDYAAMFRFFADRDLYRRD
                     RDTTLLRRLHPDLMTFEDWLHHTGWTG"
     gene            complement(14831..15655)
                     /locus_tag="AOB60_RS22395"
                     /old_locus_tag="AOB60_21540"
     CDS             complement(14831..15655)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579354.1"
                     /locus_tag="AOB60_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21540"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_102924741.1"
                     /transl_table=11
                     /translation="MSTEIDWPGGKKVAALVTVALELWSPGHGPAYAPMAAAWPLSGVD
                     DTHSASWVDYGVTTGIGRLLDILGDLPATVGINGLVAERYPDTVAAVHQAGHEIAGHSW
                     TQDVVPALLDVDTERDNIRRCTDVIERVTGVRPTGWMSPRATGSKHTCDLLTEAGYRWT
                     GDHNDHDLPQVLPTAHGPLVSLMHSDHSDVRSAAAGPYAYRDLHRALLDHLRAAPGPGV
                     FHLTVHAHVGGRPLLASMVAQILDHLRASGDVWVATHAQVAEHVLTHQGVTR"
     gene            15745..16095
                     /locus_tag="AOB60_RS22400"
                     /old_locus_tag="AOB60_21545"
     CDS             15745..16095
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579353.1"
                     /locus_tag="AOB60_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21545"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_102924742.1"
                     /transl_table=11
                     /translation="MHEYSGSVFLADCPARLAIEIIADKWAVVVLFALSREPCRHGELV
                     DLIGGISRKVLTQTLRRLQGYGLVDRHAEAGKVEYVLTDLGRTLVQPITVLTQWAHEHG
                     GAVVEFQESETG"
     gene            16436..20659
                     /locus_tag="AOB60_RS22405"
                     /old_locus_tag="AOB60_21550"
     CDS             16436..20659
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538393.1"
                     /locus_tag="AOB60_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21550"
                     /product="bifunctional nitrate reductase/sulfite reductase
                     flavoprotein subunit alpha"
                     /protein_id="WP_102924743.1"
                     /transl_table=11
                     /translation="MASGSKDGSVRTVCSYCGVGCGIVLDVVRDPADGRRRVAKASGDK
                     AHPTNSGRLCTKGATSADMMAAPGRMAKALVRAERGAQPVETEVGEAIASVAGRLRAIL
                     DEHGPDALSFYVSGQMSLEAQYLANKLAKGFVRTNQIESNSRLCMASAGSGYKLSLGAD
                     GPPGSYQDFDRADVFFVIGANMADCHPILFLRMMDRVKAGAKLIVVDPRRNATAEKADL
                     FLQIRPGTDLALLNGLLHLLVANGHTDEEFIAEFTEGWEEIPAFLVDYPPERVAEITGL
                     AENDIRRAAQWIGEAGDWMSCWTMGLNQSTHGTWNTNALVNLHLATGAICRPGSGPFSL
                     TGQPNAMGGREMGYMGPGLPGQRSVLVDSERAFVERLWQIPEGSLRTDVGRGTVEMFQE
                     LAAGAIKACWIICTNPVASVANRKTVIAGLEAAELVITQDVFAETETNAYADVVLPATL
                     WAESDGVMVNSERNLTLVPGVVDPPGQALPDWQLIARVAREMGFVEGFGHASAEEVFEE
                     LKQAWNPTTGWDLRGVTYERLRTTPVQWPAPTADGPDRNPIRYLNDGVSQTLVEREDGT
                     LPRLAFPTASGRARFYARPHLPAAELPDDDYPFMLTTGRLQHQWHTMTKTGKVAKLTKL
                     DSGPFVEVHPEDAGALGIAAGDHVEIASRRGRAVLPAVVTDRVRPGTCFAPFHWNDLFG
                     EYLSINAVTNDAIDPISFQPEFKVCAVTLTKTAAPVPQARPGIRPEATPAAAAHEDEPV
                     HPVPDQGGATARSNAAVHALAGMFGITDLTPAPLVEPERRYLSGYLAGLALNPPDGDVP
                     VLPSDAPLSPGSALWVGGVLAGMFSRSAVPVDQAPATRESELGPARTTSSAADAAIPTR
                     RLVILWASQTGNAEEFATSAAAHLTAAGRTPELLPMTDMAPAQLVPDIDLLLITSTFGD
                     GDAPDNGADFWQALSAPTIGPLEGIRYAVLALGDSTYDDFCGHGRRLDERFDALGATRL
                     VGRTDCEPDFEQTAEQWLGQVVTALATPDNSHSTAATAPPAPEPVGYTKASPFSTLLIG
                     NRLLSLPGSQKEVRQFTFDTRDHELAYDAGDALGVWPVNGAGLVAEWLALTGADPDEPV
                     ELGDGARLSFEEALRTRLDITRITTDLLKFAVERTGSQDLKRLLRPDNKDALARWSWGR
                     QAADVIGVFPVRASAPEWSAVLKRLQPRLYSISSSPLAHPSEVRLTVSVVRYTNDLGRD
                     RRGTCSTYLADCADDGPVRVFVQRSPHFRPPADPATPMVMVGPGTGVAPFVGFLQDRRA
                     RGHTGPNWLFFGEQRQATDFYYREELAGFQASGHLDRLDLAFSRDQRNKIYVQDRMREN
                     GARLWQWLQDGAHFAVCGDAGRMAKDVDQALKEIATTHGGMDADEATAYVRRLAADKRY
                     VRDVY"
     gene            20828..21739
                     /locus_tag="AOB60_RS22410"
                     /old_locus_tag="AOB60_21555"
     CDS             20828..21739
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-144). E-value:
                     1.2e-12. Score: 39.9. Matches aSDomain:
                     nrpspksdomains_AOB60_RS22410_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="AOB60_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_21555"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_102924744.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-09, bitscore: 34.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.7e-11, bitscore:
                     41.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.3e-07, bitscore:
                     28.8, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNNSTSSVRPAPPIGGFQEIDGRRVFVQRSGSGGPAVVFLPGAS
                     AVGLDYFGVQQQVSQFTTAVVYDRGGTGYSDPLPLPRTAAAVATELHDLLHAQHIAGPY
                     VLVPHSLGGFYAHRFAQLYPQDVAGLVWLDAFHRDWDDFMPPAAQLTAVEQMAPGREQL
                     EQLRPALREMFAELLADYPEHLRQALVDAKVSDAWTHIGIAERTKLAELATELRAGPNI
                     PDVPVVALTVVGTDPAQQVLTSERTLQEMHEGHTRMDAALVNAVSHGEQRIVSDTSHHR
                     LCFDRPDAVVQAIRDVVARARP"
     aSDomain        20933..21259
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AOB60_RS22410_Abhydrolase_1.1"
                     /evalue="1.20E-12"
                     /label="AOB60_RS22410_Abhydrolase_1.1"
                     /locus_tag="AOB60_RS22410"
                     /protein_end="144"
                     /protein_start="35"
                     /score="39.9"
                     /tool="antismash"
                     /translation="PAVVFLPGASAVGLDYFGVQQQVSQFTTAVVYDRGGTGYSDPLPL
                     PRTAAAVATELHDLLHAQHIAGPYVLVPHSLGGFYAHRFAQLYPQDVAGLVWLDAFHRD
                     WDDFM"
     CDS_motif       21131..21190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AOB60_RS22410_0001"
                     /evalue="7.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="AOB60_RS22410"
                     /protein_end="121"
                     /protein_start="101"
                     /score="15.2"
                     /tool="antismash"
                     /translation="GPYVLVPHSLGGFYAHRFAQ"
ORIGIN
        1 cggagctgcc caagaccggt gtgtccgcgc cgagttgctc ccgtagccgg gcgcgccggc
       61 tccgctgccg ggccaatgtc tgatgcagcg tcagggcctg gtccatcacc agcgacgcct
      121 ggagttcggt catccggagg ttgtcgccga cgagtgcccg ttcgtcgtcc cagtcgggca
      181 gtccacgctc gttccgaacg gcgcccaggt ccgccatccg gtagacccgc tcgaccacct
      241 cggcactgcc ggcgaccagt ccgccctcgc cggaggagat ctgcttggac tgctggaagc
      301 tggtgacggc gacgtcggcg agttcaccgg cccggccgtc cgtcgacgcg gcgccgagcc
      361 cctggcagac gtcctcgatc agcgggaccc cgagccggtc gcagagctgc cgcacccgtc
      421 ccgcctgtac cgcgtgcccc tgcacatgga cgatcatcac cgcggcgacg ggctggtcgg
      481 gcgattccag cgccgtggtg tcgggggtga gggcggtatc catgtccagg gggacgggta
      541 cggcgccgac cgcggagacg gccatcgcgc acgcgatgaa ggagtaggcg ctgaccagga
      601 cgcggtcacc gggaccgatg cccagggcgc gcagggccag gcgcagtccg acggtgccgt
      661 tggacactgc cgtggcggcc tccttgcgga agtagccggc gaagtggcgc tcgatgagcg
      721 tattggcgga ctcgcggtcc ccttcgacgt agcggaagag ttggccgtcg gcgagggtcg
      781 cccggaagtg ggtgagggac tgcggatcct cctgcgacag gtcgaagaac tgatgggggt
      841 tgatcaccgt catgggggtc atccaatctt gacgagaagg ggttccacag cccgccggcc
      901 gccggtcagg acgcgcttct cgcaccggtg gaacatcggc agtgcggacg gtggttgcgg
      961 gtgcatcggc tgcacgggtc cgaggtcgtc ggccagttgc ccgatgtggc gggcggtggc
     1021 ggacggcgcc gggtagagcg gcagccgggt ccagccggcg ctggatccgg gcggtagggg
     1081 cggaaggcgg aagtgtcggg cgaggtcgct gtcccggaag cggtcgacca ccgccctgcg
     1141 gcgggcgagt tgccgatcgg cgcgggcgat ggcgtccggg agcaggggca gcaggggggc
     1201 ggggaagcgc gcgggcgacg ggggacgcgg ccggtgccgg tccgtcgtgt cgccccgggc
     1261 gaccgctccg gagaccaggt cggccgggcc gaggagcgct cccccggcgc cgagcgacac
     1321 cggtttggag gggccgaagg aggcgacggt gagcgtgccg gtggctccgg cgggcacgcc
     1381 ccgcgtcgtc gatccccagg tctgcgccac gtcctcgatc accgccacgt ctgggggcag
     1441 tgcctgggcg atgccggtga cgtcgcacgg cagtccgtac tggtgcaccg cgatgaccgc
     1501 gcgggtgcgt gcggagcagg ccgcggccac gtcgtcccgg tgcagggtca ggtcctcgcc
     1561 gacgccgacg aacaccggca ccgcgccggc gcggacgacg gcggcggcga cggagtggca
     1621 gccgacgtcg ggcaccacca cctcggcacc cgcgtccacc tccagcacct ccagggcggc
     1681 ttccagcgcc gtgccgcctg aggcgcagaa ttccgcggcg ggctggcccc aacggtgcag
     1741 cagatcctgg acggcggcgg ccaccgcggg gtcagtcgaa ggcatgccgc agccccttcc
     1801 ccgcctcgtg ggcgccggcc acccgggcgt ccaacgccgc gcgctcccgg gcccggagcg
     1861 ctcccggctc ggccgcaccg caccacacgt ccgcccgcgg cacgcgctcg gtgtggagca
     1921 ggttcttcag cgcgtcgggg ctgccgtgga ggtccaccgt gcgcacgccc cggcccgccc
     1981 actcctgccg gagtccctcc gtcagcaggt agagcccggg cgagtagcgt cggtaggtct
     2041 cgtcgtagga ccacttcagg ctcatcagcc ggtcctgcac ccgggcgtcc agccggaagg
     2101 cgacggggcg ttcgccgtcg aggaggaacg cggccgtgat ctctccggtg tcgaccagcc
     2161 ggccgtagag tgcgtcctgg ccgccgcgct gccgcatgct ctgtccccgt gcggccttcc
     2221 acgagcggtc gtcgactgcg aggacgtctg caaaggcgag cggcccggac cggcccggtc
     2281 gtacggtcag gccgtcgcgc tccaccaggt gccgtttgcg gcggagttgg gagctgcccc
     2341 gttccagggc gcgttcccac aggtcggcgc cgtcgtggga ccagtcgatc agggagttgg
     2401 gcggtcgccg ccaggtcgtg cagccggccc gggcgcaggc ttcggcgtgg ggcgcggcca
     2461 ccagggggag gtagaccgac gcgccggtgg cccggcggac ggacgtcacc aggcgggcga
     2521 gtcgctccgg gtggccgtgc tcggtcagca ggggctcgtc gtcgccgacc gccgtgagca
     2581 cgtccccgtc ccgggtgaag gcggcgatgc cgtcgggggc gagggcgacg accacgcggt
     2641 ggcccgcggc acggaccgcg tgggcgtatc ccggagactg ctggagccgc gtgccgtggc
     2701 gccggtatgc gcgcgcccag gcgtcctcct gggctccggg gagggcgtcg aggtcgacca
     2761 ggcgcaggtc gtgggccggc tcgggttccg gtacggcccg gccgcccggc agcgggtgcg
     2821 gcgccgcggg gtccgcggac cggcggcggg tgtcgaggtc gggttcggcc ggacggccgg
     2881 tggcggtcat ccgaactccc ccgcgtccga gccgggtcgg cccgagcgga tccacctcag
     2941 ttgcggatag ccgcgggcgt gggcgccgaa cccggtcatg aagcggtcga tgctgggcag
     3001 cacactgccc tcgaagtcga agacctcggt cccgggctgc cgttgcgccc aggtgatcgc
     3061 ctcgtcgacc agcaggctcg gcaccccgcg cgcgcccgtg cggtcgaacc aggagtgcat
     3121 gaggaccgcg gcgccgtcgc agagcagtac gaacacctgg ccccggcaga ccccgtccgg
     3181 gtccgtcgcg gcgaggcaca gcgccggttc ctcccggccg atccgcagtc cggatcggcg
     3241 tcgggcggcc accgccggcg ccggctggcc gaccaccgct cgggagaagt cgaagctgtc
     3301 gagcggggcg ttgtgcacgg tgtgccgtcg ggcggcggcc cggatgtggt tccgggcggt
     3361 ggccacgtac gcggtgcggg ggtcgcgccc ctcgcgcagc tcaaggattc gggtgtgccg
     3421 gcagagcagt tcggcgccgg cttcggacag ggcggccacc tcgccgaagc gcggatccat
     3481 cgggagctcc gccgagtcca cgcgggccat cagcgcctgg gtcatcgagt ggaccgcacg
     3541 gtggcggtcc acgggatgca gccccgggtc gctccacggt gcggcgtagg gcaggagccg
     3601 gaagggacgg cgggcggcgg tgccgccgtc gtccagcggg acgacccaga cgcccgcggt
     3661 gcgcccggcg cgggtccgac agacgaggtt gagggtatgc ccgtagagct cggccgccgt
     3721 cggcgagttc cacacctgca cgggcaggcc ggcgacgacc ttggcgagct cgtcggggga
     3781 aacggtgtca ctgtccatgg ggcccttccg aacgggcggg gccggctgaa gcggcgcccg
     3841 gcgagacgtg gttcacatcg cgtcgagcag tgcgaaggtc tcctgcaggc tggtgggcac
     3901 ctgaccgctg gtggccgcca tgtcccgggc catgtggagt tcggacgtcg tccggtcgcg
     3961 caccacggcc ggtgcgccct gcccggtgac gatggcctcg tcgaggtccg agtagtgcgc
     4021 gagtgcccaa ctggagccgg tcgaggtggc caacgcgccg cgcagcacgt cggggtcgac
     4081 gccgagtgcg cgtccggtgc gcagtgcctg gagcgcggcg tgccggttgc tgtagaggag
     4141 ccagttgttg cagagcttca cggtcatccc ggcgccggtc ggtccggcgt gcacgacgtt
     4201 gtcggcgtag cgttccaata ccggccacac ggtgccgagt tctgctgccg agccgccgac
     4261 gaacagggac agtgagccgt cgcggaccag gccgtcacgg cggctgagcg cggcgtccag
     4321 caggatgtgc ccctgttccc gcaccgcgtc ggccagttcc cggacggtct gcggggtgag
     4381 ggtggtgtgc agcaccacgt gggagccggg gggcgcggcg gcgcacagcc cgtcggcgcc
     4441 gaagagcagg gtgcgcacgt cgtccggtcg cttgacgacg acgaggtgga cggtggcggc
     4501 gcgggcggcc tccgcggctg tcgcgcagcg gtggaagtgg tccgcctccg gcgccacatc
     4561 ggccaccggg tcgtaggcgt gcagttcgac tccgcgcgcc accaggcacc gcgcgatgtc
     4621 cgctcccatt tcgccgagac cgtacagggc gaggttggcc acgtcgtgtt cctttcgtga
     4681 gttccatcgg gtatcgacgg ccggtcccga cggcggaaac cggcggcagc gggatctcag
     4741 acgggggctt cggcccgtgg tgcggcggcc gcggctcgcg atctggccag taccagcgcc
     4801 agtcccgaac ccaggcccag caccacgatc gtgccgaggt agaccgtccc cactgacagg
     4861 caggtcagca gtgcggcgac gaggagggat ccgaccagtt gcgaaggccc ctgcaccgcg
     4921 ccgaagacgg cgaacgcctg cgccgatccg gccgggcgcc aacggtcctg gacttcgctc
     4981 tgcagcgccg cgtcgccccc gctgagcagg cccaccacgg cgtagaggca gatcgcccat
     5041 accgggtgcg cggcgctcag gccgaacacg atctggacgc agaagccggc gaggacgatc
     5101 tgcggcaccc gcgcgcgggt ccaccgtccc aacgtgccgc cggagacaag cactccgctg
     5161 atcatcgccg cgagggcgaa gcaggcgttc gccgtgcccg cgatccagga ccggtcggat
     5221 gcgccaccgg tcagcagcgg cacgaacatg ctgaagccga gggtgtgggc gagttccatg
     5281 agcagcagtg cggcggtgaa cagtcccagg cggcggggcg cgaacacctc ccgccacacc
     5341 ccggcggcgg acggccgccc ttcgccgccg gtgtccggct ccgccgcccc ggggccggcc
     5401 gaccccgccg cgaccgcgga cttgtgcagc ggcgctcggt tgatcaccac gaacaccacg
     5461 aactgcagca ccaggccgac cgcgtacgac agggcacaca gtcccaggga cgcctggatg
     5521 ccgatcgacg acgcgagcac tcccccgagg gcccagccga ccaccacgga tgcctgggtg
     5581 gcgacggcca gcatcgcgtt cagccaggtc agttgctcca ggccggtggt ctggccggcg
     5641 acccaaccgc gcatggcggg gaggtagaag gccccgaagg aggcgaagag gaacatgccg
     5701 gcgtagatct gccaggcgtg caccccaccg ccgcgcacca gcagccagag cgtcacggcc
     5761 accgcgaacg ctccggtgtc cgacaacagc atcacccagc ggtggtcgac gcgttggttg
     5821 acgatccgga ccacccggac gaggaggagt gcgggcaagg cgccgaccgc cacgaccagg
     5881 ggtgcgctcg cgggggaacc cgtcacgcgc agcgcgagca gggacagcag aagcaggagc
     5941 agtgcggagg tgctctggct ctgcagcgtc gacacgatta ccgtgccgac ctcccgcctt
     6001 tcggctgcgc cgaacccttg ccaaatctcg gctcgggtac gggtttggct ctggggttgg
     6061 gtctggggtt gggtctgggt ttgcaccgat gtctgtccca ctcttctcac ccccccggat
     6121 tccgtatttc ttttcgactc accgcgaaga cgcgcagcgt tcacaccgtg ccgcccaccg
     6181 ggacgggcag tccgcgacac caccgcttct ccgccgcttc actgctccac tgctccacca
     6241 cttcttcgtt caccgcaggg aggaattctc caaacagcga ttcatggaaa cccaagcatg
     6301 gccacttgga cgcggtcaac caagctcggt ccgcacctgg gcctttggcc gaaacaccga
     6361 cgcctggtcc cgcactcgcc gccacaccgg gaacaatgcc cccgaacccc cgccccgcgc
     6421 ccctccgaac tccctcccgg ccccttgaat taccgcctga agaacggcga acaacgactg
     6481 cgtgacacca ccccgacact tccgcgagaa caccatttcc cggaagcccg ctgcccgtcc
     6541 gacgctcttt ctcagcaccc ggacgatcga atcaggtcag catgacaagc cgcacacaga
     6601 cccatgaccg actattcata cactcacaag aagagcgaaa atatcgcgcc ttcccgaatg
     6661 ggcgagaaaa tatcggctgt ttccgcaccg cccttggcgc agcccagccg gactcctcga
     6721 acatcgaccg ccgagtccgg gaaaaacagt cccgtcgctg gccgatttcc cacggcgtgc
     6781 gccggagcag caatgcccgg cgggtagcgc atttgaccgg tgggtagcat ggcaggactt
     6841 ccccatccga cagcccattc cgcccgccgt cacctcaaca cggcggagca accagccgtc
     6901 ggggaccatc cgttcgcccg gcccgcgacc ggcccctcca tttccctccc tcacgcgcct
     6961 cacaaggagc cctgaacagt gacacccgcg cagtgggaag cattgctcta cgactggcac
     7021 aacgcccacc ggctgcgccg gcaacgcaac gacaccgcct attgggcccg cctgaccgag
     7081 cagcacgaca ccgtgctggt cctcggggcc ggcaccggac gcgtggcgag caccctggcg
     7141 caccccgcgc gacgccgggt gaccgccgtg gacctcagcc gggagcgact cgcccggatg
     7201 ccccggacgc cagggctgca cccggtctgc ggggacatgc gcaggctccc gctccgggga
     7261 tcccacgcca ccgccgtcat cccgtactcg acgctccaac tgctggtaac gccgcacgat
     7321 cggcagcggg ccctgacaga ggccgcccgc gtcctggcgc ctgggggctc cgtccatatc
     7381 gatgtcagcg agagtttcga cgcgcggacg gagaccgact ggcagatcgg gctcgccgag
     7441 ccctgtcgcg aagccggtgg cccggtggag gaatgggaac ggcaccggct gcacgccgac
     7501 cacgtggtga tcgagaagca gttccgtcga tccggccggg tactgaccga ggtgacggaa
     7561 cgctgggcct tccacagcgc gctcaatctc gccgaagcgc tcgcgcaggc gggcttcgaa
     7621 ctcgtcggaa tcgaccgcgg atacggtgcg gacctctccc cccaccgcct catctaccac
     7681 ggccgccgca cgcattgagt ctcggcgccg caccgacggc cccctcctcg cctacatccg
     7741 cgacatcacg tacgcggcca tgaccggtct tcgcggacag cgtctcgacg tgggacgagg
     7801 acgagggctc caggcacata cctgggagct gtacacgcgc aggacgcttc ccgaaaacac
     7861 acgccgggcc gactgcgatc tgttagcaat tgaggatgga acccgatcgc gtcaccgatg
     7921 aacggctaca tggcgtactc gccgaactca tgcgcaggga accactgttc cacaggccgg
     7981 agttcgggac gtcgcgggcc gatttcgagg ccatgacggc gcccgacttc tgggaaacgg
     8041 gtgcctcagg gcaacgctac agccgcgcgt atgtgctcga tgtccttgag gagcgctctc
     8101 aggagccacc cgtcgaggag tgggagactt ccgagttcca ttgccgggag ttggccgccg
     8161 atctgtatct cctgacgtac accctggtgc tcaacggatg gagaacccgc aggtcaacga
     8221 tctggcagca ggcgagcgac gggtggcgca tcgtctacca tcagggcacc cccgtcctag
     8281 acgcatgacg ggtgagggtt tccctcaatt cccagcagcc acaacagaat atgacgccac
     8341 ctgaaaacca cctacgcctc cgcgcccgcc cctcccggaa ttccgattat gtctgctcat
     8401 tgccgggtat tgatgcggac attgggctgc cgagcctccg catgaggggg ctgcgagcgg
     8461 ccgccactcg ttggacatgt gacgctgtcg atgtagggct gtcgctgtgg ggtgggggcg
     8521 ggaagtgcgt tggacgtcaa aggtgtgcac catgcttatg ggcgtcgcgt ggtgctgcgc
     8581 gggatcaaca tcagccttcg gcggggcgtg gtggccggca tcgtgggtga gaacggcgcg
     8641 ggcaagtcga ctctgttgaa aatcctcgcc ggtgaagtgc gtccgcagcg cggcgtcgtc
     8701 gtccaccgcg gccgcttcgg atactgcccg caggacgtgg tcctcaacga cgccctcacc
     8761 gtccgtcagc acctgaagtt cttcatgacc gccttcggcc tcccggatct gtgccgcgcc
     8821 gagggcctca tggaggtgct gcggttctcc gagtacgccg acgaacgcgc cggagtgctc
     8881 agcggcggca cccgccagaa gctgaacctc accctcgccc tgatgcacga tccccaggtg
     8941 ctgctgctgg acgagcccta ccagggcttc gactgggaca cctaccggcg gttctgggac
     9001 ctcgcggtcg ggctgcgcga ggccggccgg tccgtgttgg tcgtgtccca cctcgcctac
     9061 gacaccagcc gcctcgacga gctgtggtac ctggagggcg gagtgctgcg cccgcgggcg
     9121 gaggcggcgg catgaggcgg cacctgacct tcttcgtgac ggctgcccgg tacgacctgg
     9181 tcgtgcacgc ccgcaatcgg ttcgccatgt tcctggtcgt cctctacgtc ccggcgtggg
     9241 tgaccctcgc ccacgcggca ctgcccgaca aacccgcacc catccgactc aactccaccg
     9301 gcgagttcct ctccccgccc ggcgaccagc tctcccagat caccggcgcc ctcaacgccg
     9361 tcaccctgat cgccgggttc atgatgttcg ccgccacctt caacggtgga cggttcgacc
     9421 gacgactggc catggcaggc catccgcgca tccacctcgc cctggccaag accacctcgc
     9481 tggcgctcgc ctgcgctgcc gtatcggtct acgccaccgc cgtcacctgc gcggcctgga
     9541 tcccgcgcca gccggcgctg ctggccaccg cactgttctg cgacgccatg acctacggcg
     9601 cgctcggtgt gctcttcggg tgcgtactgc gacgggaggt cgagggcatg ttcgcgatgg
     9661 tgatgaccag cgtcatcgac gtcgcgctgc agaaccccat cgccaacacc ggcgccaaca
     9721 gtccactggt ccggctgctg ccgtcctacg ggagcatgca ggccgccacc ggtgcggggt
     9781 tcacgaacgg cacgatgacg agttgcctgg ccgtccagac actgtggttc gccggtgccg
     9841 cgctgctggc cctgctggcg ttccaccgcc gcacccgcag cgccttcccg aggacccggc
     9901 gccctcggac accgacccgc ggccggccgg cacacggtac gcgatgagca cacttcccgg
     9961 cctgcgccgg gcggagacga gttgagggga gggccctgcg gtgctgttgc gacgatggct
    10021 cgacgcagcg gggatccatg acccggtcct gcggcagtgc tacacggtgt gcatccgcga
    10081 catccacaag tgtgatgcgg ggagggcagg ttggtgggcg ctgcgggcgg cgccggcggc
    10141 gctccgaccg cacgtcgcgg cgctggtcgt ccacgggtac aaggccgacg cgtgcgccga
    10201 caccgggccc gtcgaggagc gggcccgtcg cctggacgcg tacggcacgg cggctctcgc
    10261 cgcgatcgag tcgggcagtg ccgccgaccc ggtcctgcat gccatggcac acaccttccg
    10321 cgccttcaac ctgcccagat cgctggcgga ggacatgctc gccgcgatgc accacgaaat
    10381 cgagatgcgc caacccgcga cgtatgcgga atggcggcac tgggcgacgg ggatcgccgg
    10441 cactccgatc gtcgtgctca tgcttgtcct gcggtccgac cgcatcggcc cccgggaacc
    10501 gctggtgcgt gagctcggcg agctgttcca actgaccgac gtactctgcg acctggccga
    10561 cgacctgacc gaccggcggc tgtacctgcc ggcggacgac ctcgaccggt tcggcgtccg
    10621 cgcccaggac ctcctggccg gacactggac gccggccacg gcggaactca tcgccttcga
    10681 ggccgatcgc gtccgacacc gcctccccgc cctggtcacc gccttggacg acagtcccgc
    10741 cagctcctgg gccgacgcca tgggccggca ctgcacgctg ctgctgggcc tcgtgcgcgc
    10801 cgccggcgcc gacctgctgc accggcccgt acgaccgccc gtctccgcgc tgttcgacgt
    10861 gtggcagcgc cagtggcgca ccgtcatccc ctgctgaacc cgaaaggccc cgtatgaccg
    10921 ccaccgcctc ccggcccacc gaccccctga tcccgctcat cgaagccgag ctgatccgct
    10981 cggtcggcag tggcgaagac ctgttggaaa cggcatgcct ggacgccctg ttccccggcg
    11041 gcaaactgct gcgccccacg ctgtgcgtgg aatcggcgcg ggcggtgggc ggccgggccg
    11101 agtcggtgct gtccttcgcg gcggccatcg aatgcctgca cgtggccagc ctcgtccacg
    11161 acgacatcgt cgaccaggac ccggtgcgcc gcgggcgggc gtcgaccgcc gaacggttcg
    11221 gcatcgccga ggccctgctg gccggagacg ggctgttcac cgcggggtgg gcggccatgc
    11281 tccgcggcgg cccggccgat cgtgtcctgg ccgcgtcccg ggcgatcgcc gaggcggtcc
    11341 acgccatgtg ccgcgccagt atgcgcgaga tcgagatccg cgaggacctg acctgcgggc
    11401 ggtcggccgt actggaggtg atccgcggca agaccgccgc gctgaccggc gccgcctgcc
    11461 gggcgggcgc gatcctggcc gacgcgacac cggagcagat cgacgccctg caccactacg
    11521 gagaacagct cggcatggcc ttccagatcc gcgacgacct gttgccgtac accgccgccg
    11581 acgcactgac cggcaaatcc gccgtcagcg acgtcgccaa ccgccagccg acgctgcccg
    11641 tcctgctcgc ctacgagtcc gcggacgccc acgaccgccg acacctcacc gagatcttcc
    11701 atggcaatgt cgatctcgcc acggcccacc gtgacctgct cgacgtgctg gcccggaccg
    11761 gcgccatcgc cgaggcggca cgccaggcgc gggcctgcgc cgcccaggca cgcgcggccc
    11821 tcggcggcct gtcggccacc gggcgcctcg cctggctggc ggactccgcc gccgaccgcc
    11881 accagtgacc ggaactgctg ccggggatgg tgccggaact cgcctcggag ctcgcccggt
    11941 tggggctacc gacgcattgc cctccgcggc gccacggccg aggtagggac ttccccaccc
    12001 cgttccaggg ggcctgtcgg agtgcctgag accggcgcag catgatgcgc tggccgcacg
    12061 ggattcgtgt gacggaaggt ggacaggtga agagtcggat cgggtactgc gcctggatcg
    12121 tgggggtggg gcagttcttc gccgtccacg tcgtggtcga gtcggcctgg gcgagaccgt
    12181 acagctgggc gcggaacaac atcagcgact tgggcaacgc gctctgtgca gtgcagccgg
    12241 atcccgagcc gcgctatatc tgctctcccg aacacggcct gatgaacgcc tcgttcatcg
    12301 ccctgggagt gctgctcgtc gtcggcgtcg ccctggccgg tggcgtcgtg tggcgcagag
    12361 gaccgctcgc ggccgggtcc cggctgttgc tggccggtgc cggcgtggga ttcgtgttgg
    12421 tcgggctggc ccccgctgac gtcaacgaga accagcacgt cctgggcgcc ctgctcatca
    12481 tggggacggg caacatcggg ctcctgctgg ccgcgttcag cctgacggat cgtcttgcgg
    12541 gcccactgcg ctggggtacc ggcctgctgg gcggcgcagc gatcgcggcc ttcgggctgt
    12601 tcctgaccga acactacctc ggcctcggca tgggaggcat ggagcgcgtc gcggtcttcc
    12661 ccctcctggt gtgggcgctg gccgtcggca ttcatggcct cgtccgccgg ccggaccgcc
    12721 gacccgaggc gatgtcggca cagcgcctcg cgcagccgct ccgccgatga gtcaccgcgc
    12781 cgttcggcta ctcctacccg gatcccgccc agcggattcg gcgttcccct cccgtcatcc
    12841 ccagtcacag gagtagtggt cgtggcacgt gccggccggg tggcccgccg ggagcggagt
    12901 gaggagtgac tgtcggccct ggccgagagc gagccggagg aggtgtccca ggagctggac
    12961 gaggaggtcg tgcgggaccg ctgcctggga ttcgccccgg cggatccggc acggccggcg
    13021 gccctggcgg agcgggtccg ggaagaggac acaccccagg aggacgtgct cctggccggc
    13081 atgtggggcc gggcgctgcc gggccgatct tgaagggctg tccatgacac ggcgtgcggg
    13141 gccgggcgac aatcgcgccc atggatgacg ccttcactct cctccggcag gtcgccgagc
    13201 tcctgcccgg ggacgccgcg gcagagtgcg gcatgacggt cgaggatgcg cgcgatgcca
    13261 tcgagctcca ggaatgggag atggcgctgg acttgctcat cgagatcgcg gaggtccatc
    13321 cggtatccct ggctctctgg gacacgctcg ccgaggcagc tcgacagatg atgctcgacc
    13381 gcagccgtcg tcggtgcgag tggcacggct gggaagtccg gcacggcacc gtccgcgcga
    13441 agctgaccct gttgggggcc gacgagggcg gacgccggag tgccttctcg ggggatggtc
    13501 agctcagacc cctgtgggac atcggtggcc gcgccgcaga cggacagcga gaggtgcgca
    13561 tcgcacgtct ttgggtggag tgcgtccaag aactcggccc cggcgagacc gccgacgtcc
    13621 ggctcgctcc cctgagcccc gagcagtggc ggcatctgaa gcccggtgac gtgatcacca
    13681 tgcacgaggg ccggcctgcg gtcggcacgg ccaccgtcat cgaggtccgc ccgcctcgca
    13741 cctgaagcct gcctgtcggc ctgcctgcct gcccgtccac acacgcaggc aggcgggcgg
    13801 cccgtggaac gctggcgacg tagacggcac gaagccggcg accgaggacc ggcgtcacgc
    13861 aggagaggga cgccgccggt tggactgacg agcgcggccg tgggtggtca tcccgtccaa
    13921 ccggtgtggt gcagccagtc ttcgaaggtc atcaagtcgg ggtggaggcg tcggagaagg
    13981 gtggtgtccc ggtctcggcg gtagagatca cggtcggcga agaaccggaa catcgctgcg
    14041 tagtcgtggc cgaagtcggg tacggcggcg tgcagttcgt cgtgcgacat cgggaggtag
    14101 ctgctggggg tgcccgagac ctgggtgaag gtagcggcga tctcgtcgcc ggtgaggctg
    14161 tcgccgatca ccgcgagatc gcgggcgccc caggactgcc agttgtcgaa caggtggcag
    14221 gcgaaccagg cgatgtcgtc gagggcgacg agcgggtagt gggcggcgcc gagggggagc
    14281 ctgaagacca ggccgccccg accgtccggt cgaggggtga gccggtcgcg cagattctcg
    14341 aagtacggcg ccgtggtcag taccgagacg tggttggtgt accagccgtc ggtctccttg
    14401 cggagcatct cctccgaccg catcaggtcg atgtgggcag caacggcggc tttgctgtcg
    14461 aagtgcggga cggggcggcc ggtcagggac accgcgctgt ccaacgagga ccagacgaaa
    14521 cgctccacgc cggcccgctc cgcggcggtc agcagctcca ggccctgccg atactcaccc
    14581 acggcgctgc ccgtcgcgaa gaagtcggtg ttggcgaaca cccggtcggc ctgccccatc
    14641 agggcgtcga gggccgctgg gtcggagtgg accagtcgca ggcggtgggg cgcagtggcg
    14701 gcgagttcgg tggcgtgagc ggactccggg tgtcgggtgg ggacggtgat ggtggcgtcg
    14761 gtggtggcga gcaggtgctg gatcacgtgg ctgcccatgg ctccggtgcc gcccacgacg
    14821 aggacgtggg tcatcgcgta actccctggt gggtaaggac gtgttcggcc acctgagcat
    14881 gggtggcgac ccagacgtcg ccggacgcac ggaggtggtc gaggatctgg gcgaccatgc
    14941 tcgcgaggag cggtcggcct ccgacgtggg cgtggacggt caagtggaag acgcctgggc
    15001 cgggggcggc gcgcaggtgg tccagtagcg cacggtgcag gtcgcggtag gcgtacgggc
    15061 ctgccgcggc actgcggacg tcggagtggt cgctgtgcat gagggagacc agggggccgt
    15121 gggcggtggg caggacctgc gggaggtcgt ggtcgttgtg gtcgccggtc cagcggtagc
    15181 cggcctcggt gaggagatcg caagtgtgct tcgagccggt ggcgcgcggg ctcatccacc
    15241 cggtggggcg cacgccggtg actcgctcga ttacgtcggt gcagcggcgg atgttgtccc
    15301 gctcggtgtc cacgtcgagc agcgcgggta cgacgtcctg agtccaggag tgcccggcga
    15361 tctcgtgccc cgcctggtgc acggccgcca ccgtgtcggg gtaccgctcg gcgacgaggc
    15421 cgttgatgcc gacggtggcg ggcaggtcac cgaggatgtc gagcagccgc ccgatgccgg
    15481 tggtgacgcc gtagtcgacc caggaggcgc tgtgcgtgtc gtcgacgccg gacagcggcc
    15541 acgccgcggc catcggcgca taggcgggac cgtgccctgg tgaccacagc tccaacgcaa
    15601 ctgtgaccag cgcggcgacc ttcttcccgc ccggccagtc gatctctgta ctcatgcgtt
    15661 tcccctgatt cggtagcttc cgctggggac gctaatgagg cggtaggtac cttcaggtac
    15721 ctggcagcgg gctagcatcg gggcgtgcat gagtactccg gcagtgtctt cctcgctgac
    15781 tgcccggctc ggttggcgat cgagatcatc gccgacaagt gggcggtggt cgtgttgttc
    15841 gcattgagtc gggaaccgtg ccggcacggc gagttggtcg atctgatcgg cgggatctcc
    15901 cggaaggtgc tgactcagac gctgcggcgg ttgcaggggt acggcctcgt cgaccgccat
    15961 gccgaggccg ggaaggtcga gtacgtgctg acggacttgg gccggacgct ggtgcagccg
    16021 atcaccgtgc tgactcagtg ggcccacgag cacggcgggg ccgtggtgga gttccaagag
    16081 tccgagacgg gctaggacgc gtcgtgctcg tggcggttgg gcggctcggc tcgtcgtgat
    16141 cgagcaccgt ggcgcggtgg cgcggtggcc cgaagcgtgg aggtgtcaag gcgtgggagg
    16201 tgctgtcgcg tctggcgccg cacaggcatg tgccggtgcg gggcgccggc gtgaacggga
    16261 ccacctgcct cacatcgtgc ggttgcggcg tgtgcgggag gcgtaacctc gggcgctcca
    16321 gtcatgtgac gggccggaaa ttcgccctcc ctacggtact ggtcgtaggt cgtgcccgcc
    16381 gccggtgggg cggtcctggc tcgggaaggc acacgcaccg cagagtgggg tttcggtggc
    16441 atctggctcg aaggacggca gtgtccgcac ggtctgctcg tactgcgggg tgggctgcgg
    16501 gatcgtcctg gacgtggtgc gggaccccgc cgacggccgg cgccgggtgg ccaaggcgtc
    16561 cggggacaag gcgcatccca ccaactccgg ccgcctgtgc acgaaggggg cgaccagcgc
    16621 ggacatgatg gccgcgccgg ggcgcatggc gaaggcgctg gtgcgtgccg agcgcggcgc
    16681 ccagcccgtc gagacggagg tgggcgaggc catcgcgtcg gtggccgggc ggctgcgggc
    16741 gatcctggac gagcacgggc cggacgcgtt gtccttctac gtgtccgggc agatgtccct
    16801 ggaggcgcag tatctggcga acaagctggc caagggcttc gtgcgcacca accagatcga
    16861 gtcgaactcg cggctgtgca tggcctcggc agggtccgga tacaagctgt cgctgggcgc
    16921 ggacggcccg cccggctcct atcaggactt cgaccgagcg gacgtgttct tcgtcatcgg
    16981 cgcgaacatg gccgactgcc acccgatcct cttcctgcgc atgatggacc gggtcaaggc
    17041 aggcgccaaa ttgatcgtcg tcgacccgcg ccgcaacgcc acggccgaga aggccgacct
    17101 cttcctgcag atcaggccgg gcaccgacct cgccctactg aacggcctgt tgcacctgtt
    17161 ggtggcgaac ggccacaccg acgaggagtt catcgccgag ttcaccgagg gctgggagga
    17221 gatacccgcc ttcctcgtgg actacccgcc cgagcgggtc gcggagatca ccggcctcgc
    17281 cgagaacgac atccgccggg ccgcgcagtg gatcggcgag gcaggtgact ggatgagctg
    17341 ctggaccatg ggcctgaacc agtccaccca cggcacctgg aacaccaacg ccctggtcaa
    17401 cctgcacctg gcgaccggcg ccatctgccg cccgggatcg ggaccgttct cgctgaccgg
    17461 ccaacccaac gccatgggcg gccgggagat ggggtacatg gggcccgggc tgccgggtca
    17521 gcggtccgtg ctggtcgact ccgagcgggc cttcgtcgag cgcctgtggc agatacccga
    17581 gggctcgctg cgtaccgacg ttgggcgcgg caccgtcgag atgttccagg aactggccgc
    17641 cggcgccatc aaggcatgtt ggatcatctg taccaacccg gtcgcctcgg tcgccaaccg
    17701 caagaccgtc atcgccggtc tggaggccgc cgaactcgtc atcacgcagg acgtcttcgc
    17761 cgagaccgag accaacgcgt acgccgatgt cgtcctgccc gcgacgctgt gggcggagtc
    17821 cgacggcgtc atggtgaact ccgagcggaa cctcaccctg gtgccaggcg tcgtcgaccc
    17881 gcccggacag gcactgcccg actggcagct gatcgccagg gtggcccgcg agatgggctt
    17941 cgtcgagggc ttcggccacg cctccgccga ggaggtgttc gaggaactca agcaggcgtg
    18001 gaatcccacg accggctggg acctgcgcgg ggtgacctac gagcggctgc gcaccacacc
    18061 ggtccagtgg ccggcgccga ccgcggacgg cccggaccgc aacccgatcc gctacctcaa
    18121 cgacggcgtc agccagacac tggtggaacg cgaggacggc acgctccctc gactggcctt
    18181 ccccaccgcg agcggacgtg cccggttcta cgcccggccg catcttcctg cggccgaact
    18241 ccccgacgac gactacccgt tcatgctcac cacgggccgc ctccagcacc agtggcacac
    18301 catgacgaag accggcaagg tcgccaagct caccaagctc gactccggcc cgttcgtgga
    18361 ggtccacccc gaggacgccg gggcgctcgg gatcgcggcg ggcgaccatg tggagatcgc
    18421 ctcccgccgt gggcgtgccg tgcttcccgc cgtggtcacc gaccgggtgc gacccggtac
    18481 gtgcttcgcc cccttccact ggaacgacct gttcggcgag tacctcagca tcaacgccgt
    18541 caccaatgac gccatcgacc cgatctcctt ccaacccgag ttcaaggtct gcgccgtcac
    18601 tctcaccaag acggcagcgc ccgtcccgca ggcccgcccg ggcatccgcc ccgaggccac
    18661 gccggccgcc gccgcgcacg aagacgagcc cgtgcacccc gtccccgacc agggtggcgc
    18721 gacagcccgg tcgaacgccg ccgtccacgc gctcgccggg atgttcggca tcaccgacct
    18781 gacccccgcg ccactggtcg aaccggagcg ccgctatctc tccggctatc tcgccggcct
    18841 cgccctgaac ccgcccgacg gggacgtccc cgtgctgccg tccgacgcgc ccctctcccc
    18901 cggttccgcg ctctgggtcg gcggcgtcct cgccggcatg ttctcccgct ccgcggtgcc
    18961 cgtcgaccag gcacccgcca cccgcgagtc cgaactcggg cccgcgcgga ccacgtcatc
    19021 ggcagccgac gccgccatac cgacccggcg cctggtcatc ctgtgggctt cgcagaccgg
    19081 caacgccgag gagttcgcca ccagcgccgc ggcccacctc acggcggcgg gccgcacccc
    19141 agagctgctg cccatgacgg acatggcgcc cgctcaactc gtccccgaca tcgacctgtt
    19201 gctcatcacc agcaccttcg gcgacggcga cgctcccgac aacggcgccg acttctggca
    19261 ggcgctgtcc gcccccacca tcggcccgct ggaaggcatc cggtacgcgg tgctcgccct
    19321 gggcgactcc acctacgacg acttctgcgg ccacggccgc cggctcgacg aacggttcga
    19381 cgcgctcggg gccacccgcc tcgtcggccg taccgactgc gagcccgact tcgagcagac
    19441 cgccgagcag tggctcggac aggtggtcac cgccctggcc acccccgaca acagtcactc
    19501 cacggccgcc acggcaccgc ccgctccgga acccgtcggc tacaccaagg catcgccgtt
    19561 cagcaccctc ctcatcggca accggctgtt gagcctgccc ggttcccaga aggaggtgcg
    19621 gcagttcacc ttcgacaccc gtgaccacga actcgcctac gacgccggtg acgccctcgg
    19681 cgtgtggccg gtcaacggtg ccggcctcgt cgccgaatgg ctcgccctga ccggagcgga
    19741 ccccgacgag cccgtcgagc tcggcgacgg tgcgcgcctc tccttcgagg aggccctgcg
    19801 cacccgcctg gacatcaccc gcatcaccac cgacctgctc aagttcgcgg tggagcgcac
    19861 cggcagccag gacctgaagc ggctgctgcg gcccgacaac aaggacgccc tggcaaggtg
    19921 gagttggggt cgccaggcag ccgatgtcat cggcgtgttc cccgtccgcg cgtccgcccc
    19981 ggaatggtcc gccgtgctca agcgtctgca accccgcctg tactccatct cctccagtcc
    20041 cctggcccac cccagcgagg tgcggctcac cgtctccgtc gtccgctaca ccaacgacct
    20101 cggccgggac cgcaggggca cctgctcgac ctatctggcg gactgtgcgg acgacggccc
    20161 ggtgcgggtc ttcgtgcagc gctcaccgca tttccgtccg cccgccgacc ccgccacccc
    20221 catggtcatg gtcggcccgg gaaccggcgt ggcccccttc gtcggcttcc tccaagaccg
    20281 ccgggcccgc ggtcacaccg gccccaactg gctcttcttc ggcgaacagc gccaggccac
    20341 cgacttctac taccgcgagg agctggcggg gttccaggca tccggccacc tcgaccgcct
    20401 cgacctcgcc ttctcccgcg accagcgcaa caagatctac gtccaggacc ggatgcgcga
    20461 gaacggtgcc cgcctgtggc agtggctcca ggacggcgcc cacttcgctg tctgtggcga
    20521 cgccggccgc atggccaagg acgtggacca ggcactcaag gagatcgcca ccacgcacgg
    20581 cggcatggac gccgacgagg ccaccgccta cgtcaggcgc ctcgccgccg acaaacgcta
    20641 cgtccgcgac gtctactgat cgaccgcgcg tccacccacg acgcacacca gccaagagac
    20701 gccagccaag ggacgccagt cggcgaacaa cagccagggg cggcagccaa aggacgtcgg
    20761 tcaatggacg acgaccgcag cggaaggagt tgaccttgac cgtgcgtcag ggttggaacc
    20821 tggtcgcatg acgaacaaca gcacttcctc ggttcggccc gccccgccga tcggagggtt
    20881 ccaggagatc gacggtcgcc gcgtcttcgt gcagcggtcg ggcagcggcg gaccggccgt
    20941 ggtgttcctg cccggcgcca gcgcggtcgg cctggactat ttcggtgtcc agcagcaggt
    21001 atcgcagttc accaccgccg tggtgtacga ccgcggcggc acgggctaca gcgaccccct
    21061 cccgctgccg cgcaccgccg ccgcggtcgc cacggaactg cacgacctgc tgcacgccca
    21121 gcacatcgcc ggcccctacg tgctggtgcc acactccctc ggcggtttct acgcgcaccg
    21181 gttcgcgcag ctgtacccgc aggacgtggc cgggctggtc tggttggacg ccttccaccg
    21241 cgactgggac gacttcatgc cgcccgcggc gcagctgacc gcggtcgagc agatggcgcc
    21301 tggtcgggag cagttggaac agctgcgtcc ggccctgcgc gagatgttcg cggagttgct
    21361 cgcggactac ccggagcacc tgcggcaagc gctggtcgac gccaaggtga gtgacgcctg
    21421 gacccacatc ggcatcgccg agcgcaccaa gctggccgaa ctcgccaccg aactgcgggc
    21481 cgggccgaac attcccgacg tcccggtggt tgcgctcacc gtggtcggca ccgaccccgc
    21541 acagcaggtg ctgacgtcgg agcggacgct gcaggagatg cacgagggtc acacgagaat
    21601 ggacgcggcc ctggtgaacg cggtctcgca cggggaacaa cgcatcgtct ccgacaccag
    21661 ccaccaccgg ctctgcttcg accgccccga tgccgtggtc caggcgatcc gcgatgtcgt
    21721 cgcccgggcc cgcccctgat tagactcggc cggaccacgt ttcacgagga cccgaggagg
    21781 acggtgctca cgatcggcca gctcgcggca accgccggcg tgaccgtgcg caccgttcgc
    21841 cactaccacc acgtcggcct gttgcccgag cccgagcgcg atgcctcc
//
