LOCUS       NZ_LJSN01000002        24475 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces noursei strain JCM 4701 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_LJSN01000002
VERSION     NZ_LJSN01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces noursei
  ORGANISM  Streptomyces noursei
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 4596274)
  AUTHORS   Graham,D.E., Mahan,K.M., Klingeman,D.M., Fida,T., Giannone,R.J.,
            Hettich,R.L., Parry,R.J. and Spain,J.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-SEP-2015) Biosciences Division, Oak Ridge National
            Laboratory, PO Box 2008, MS-6038, Oak Ridge, TN 37831-6038, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method :: SPAdes v. 3.6; SMRT Analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina MiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002891315.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 20:38:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,947
            CDSs (total)                      :: 8,851
            Genes (coding)                    :: 8,489
            CDSs (with protein)               :: 8,489
            Genes (RNA)                       :: 96
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 362
            CDSs (without protein)            :: 362
            Pseudo Genes (ambiguous residues) :: 0 of 362
            Pseudo Genes (frameshifted)       :: 118 of 362
            Pseudo Genes (incomplete)         :: 301 of 362
            Pseudo Genes (internal stop)      :: 23 of 362
            Pseudo Genes (multiple problems)  :: 74 of 362
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:29:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3912654
            Orig. end                         :: 3937129
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LJSN01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24475
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="18"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24475
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24475
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14475](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14475)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(505..2286)
                     /locus_tag="AOB60_RS18745"
                     /old_locus_tag="AOB60_18005"
     CDS             complement(505..2286)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538933.1"
                     /locus_tag="AOB60_RS18745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18005"
                     /product="dynamin family protein"
                     /protein_id="WP_258017986.1"
                     /transl_table=11
                     /translation="MDVGPRLIDALSVLRDRVDAARFPLPLGGAARARRDRAELLSQLD
                     DYVMPRLCAPKAPLLAVVGGSTGAGKSTLVNSLVGRRVSEAGVLRPTTRTPVLVCHPDD
                     HRWFAGQRVLPGLTRVWVPEQDGGEGDERDDGGGRGEGGEKGLGGGRGRAAGEPGTPTV
                     RIETDPALPSGLALLDAPDIDSLVAGNRELAAELICAADVWVLVTTAARYADAVPWHLL
                     RTAKEYDVTLVTVLDRVPHQIAAEISARYAELLQRAGLGHVPRFTIPELPESAGGGRGL
                     LPATAVAGLRDWLERHALDPAARSAAADRTATGAIASLRSRMPALAGAAAAQHAAALRL
                     AGRVEEAYEEAAERVRREVAAGEVLAGDARAHWQAHGPGGRADELLDALTRGLTALLVC
                     AVEEADERAAGAWRRDPAAAEMAPAAADGAAGAAGRIGVIVRRWRRCLEELAEEETRET
                     RGGSAGERSDPVDGEQPTALLATALLGGRRARTAGENLADLLGAQSALRLCDQGARLLT
                     RYLEHALDGERERRLAPLDRLTVPPDQQAELIAALSVVQREQRRRRPVEAWETERRTER
                     ERGRATADRCGREAVTG"
     tRNA            2598..2673
                     /anticodon=(pos:3915285..3915287,aa:Arg,seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AOB60_RS18750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="AOB60_18010"
                     /product="tRNA-Arg"
     gene            2598..2673
                     /locus_tag="AOB60_RS18750"
                     /old_locus_tag="AOB60_18010"
     misc_feature    2912..2927
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     misc_feature    3251..3261
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    complement(3584..3602)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.57"
                     /tool="antismash"
     misc_feature    complement(3591..3605)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.43"
                     /tool="antismash"
     gene            3871..5082
                     /locus_tag="AOB60_RS18755"
                     /old_locus_tag="AOB60_18015"
     CDS             3871..5082
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="AOB60_RS18755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18015"
                     /product="histidine kinase"
                     /protein_id="WP_180990172.1"
                     /transl_table=11
                     /translation="MWGNGGSRRAALVVDGVVIAAAATELLTLYDALDALSALVCPPSL
                     FALVLRRRFPVAVLFATLPSMATGHLWLAPMIAMFTVASRTARRAVVGVATAALFAATM
                     WSGYDLDGGAVDWSHHLFLVEVALMFSVGPAGLGLLFRTRSELRARLADLIASQAHGRR
                     LEAERAVAKERTRMAREMHDSVSYHLGIIAAQSGALWATAPDDTVRRDAETIRRHSADA
                     MAELREIVGVLRHGPSRADGTDARLRNVPTLVEEARLDATLDCGALETHTIAPSVERAA
                     YRTVQEALTNVRKHAPGAPVAASVRPSARGDLLVVEVRNQPAPRTPPQVAPVLDVPASG
                     YGLAGLRERVTLVGGAFRAEATADGGFVVRAELPLGPAAPRAAGPAPGHQPATAAQGES
                     GSRS"
     gene            complement(5037..5801)
                     /locus_tag="AOB60_RS18760"
                     /old_locus_tag="AOB60_18020"
     CDS             complement(5037..5801)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980774.1"
                     /locus_tag="AOB60_RS18760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18020"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_102924118.1"
                     /transl_table=11
                     /translation="MALGNALYDQKLASVYDRMYPIDHDTAQAVEFVAGRTPPDGRILE
                     LGVGTGRIAVPLAERGFRVHGIDGSEAMLDELHRQNPQTAVTTQFGDFTEEGTGGVFDT
                     VTLLLNTFFVAITKEQQLGTLRLVHEQLAPEGRFVLEAFDPAPYHHLEKPDFSMRHLDE
                     QAVMLDTLAVDRSQQLMLSTHTIIDGGAPATREHVLRYAFPFEIDLLAELSGLRLVERM
                     EDWCGTPYTSASLRHVSVYERDPDSPWAAVAG"
     misc_feature    complement(5801..5817)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.47"
                     /tool="antismash"
     gene            complement(5879..6556)
                     /locus_tag="AOB60_RS18765"
                     /old_locus_tag="AOB60_18025"
     CDS             complement(5879..6556)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474551.1"
                     /locus_tag="AOB60_RS18765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18025"
                     /product="response regulator transcription factor"
                     /protein_id="WP_102924119.1"
                     /transl_table=11
                     /translation="MIRVMIVDDEILLRSCMQRILESEADIEVPVACDGREVREAVAAH
                     RPDVVLLDLRMPEVDGLTALEGIRAHQDPPAVAVLTTFLRDEDIAAALRSGAAGFLLKD
                     ATPQELADAVRVLASGGTVLSPAAARIVVDGYLGAGPRHGGRDPRLDTLTEREQQVLEL
                     LGEGLTNADIGRRLLLSASTAKEHVSSILTKLGLANRVQAAVAAHRAAAEGNLRPSALA
                     ETR"
     misc_feature    6653..6668
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    6655..6669
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.31"
                     /tool="antismash"
     misc_feature    6657..6668
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.53"
                     /tool="antismash"
     gene            complement(6690..6908)
                     /locus_tag="AOB60_RS18770"
                     /old_locus_tag="AOB60_18030"
     CDS             complement(6690..6908)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS18770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_18030"
                     /product="hypothetical protein"
                     /protein_id="WP_039636313.1"
                     /transl_table=11
                     /translation="MSASGVVLDGPGPRALALSGPAAAATGGGRFGTALDCTVTAEDGS
                     AKKIELLVSTWDAKLVELITEHLSEPV"
     misc_feature    7089..7107
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.54"
                     /tool="antismash"
     gene            complement(7103..8137)
                     /locus_tag="AOB60_RS18775"
                     /old_locus_tag="AOB60_18035"
     CDS             complement(7103..8137)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014668864.1"
                     /locus_tag="AOB60_RS18775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18035"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_258017845.1"
                     /transl_table=11
                     /translation="MTRTPPLSLMYPLMAYDLDHLTAFGEVVRELSLERLYMGQSVLVD
                     THHAFAHLAGRGIRVPVGTSVALTALRHPLDAAIQARSLALLTGADVVAGYSTGDPAFV
                     TALRGAPYDSPRTAVAEYLTVVRRLLDGELVDFQGRYVRVDEGLPQVPHPPVSLGVGVL
                     RPRMAYTAGQVADVAITLLTPASYLRDRIVPALARGAASRDRAVPGVTSIVPCAVRRPG
                     RDPRRLAFAAHELHLGGEHYAAMLRSAGLGVDAADPWAGAGVLVDSGVFAYGTPDELAD
                     QLTGYGEAGATEIALSCAGVLLTEGLDAALADVRAIVGAMQDRAVPRADEGPGFCTSSH
                     PKLS"
     gene            complement(8161..10008)
                     /locus_tag="AOB60_RS18780"
                     /old_locus_tag="AOB60_18040"
     CDS             complement(8161..10008)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741466.1"
                     /locus_tag="AOB60_RS18780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18040"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079181683.1"
                     /transl_table=11
                     /translation="MTDQEARDQAVPEEHRRLSRDLRYWWLVLRTFWGLSPLRVSALAV
                     ATVLTAAVPATGIWLTARAVQAVVDALTRVPDAMDRLTCAAAGLVAVAVAEHILTSLSQ
                     YLNSLLQLEFTAKIGERVMVKGTRMDLSAYEDPEAYDRLQRALRESGSGTAFEVFEEMM
                     RTLTALASLVMVSWVLFSWNVWIALAILLAPLPALAAHVVFSKQGYAIEYHRAQDRRRA
                     FYYQDLTTTDSSYKEVKLYQLGPHLVGRYRSLVQEFFRVDRALARRRHGWSAALGLVSV
                     GCSAGALVFALRSTADNGRIGELAGYLQALGAVHAAATGLLLGVATLYQNTLFTGNLFD
                     YLTLPDGRITGGTRPFPRRLTHGIEFQDVTFRYPGTTTTALDRFSCFIPADTCCAIVGA
                     NGAGKSTIVKLLSRLYEPTSGRILVDGVPLEEYDTDDLQRNIGVVFQDFIRYEMPVRHN
                     IGFGRLEHLDDDARLRTAAGSSGAAEFIDRLADTYDTTLGRHFEGGHQLSGGQWQKIAL
                     ARAFLRDAPIAILDEPTAAIDAEAEADIFGRLRTICSRATSLVISHRFSTVRIADKILV
                     VEGGALIEEGTHEELLARGGTYAHLFRLQADAYLPGASA"
     gene            complement(10001..13225)
                     /locus_tag="AOB60_RS18785"
                     /old_locus_tag="AOB60_18045"
     CDS             complement(10001..13225)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327746.1"
                     /locus_tag="AOB60_RS18785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18045"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_258017846.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.6e-158,
                     bitscore: 524.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-14,
                     bitscore: 52.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.9e-29, bitscore:
                     99.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIDAIDAIDKDLTRPMPRYEALDFPLLRAPALPVEVWRETLAD
                     RDPARTRARLRAMADNPRVRHGLVAAGSGLLDGLAKVEAAQGRASGKEMRRVHSRALRY
                     LTRMSTRPTPFGAFSGVALGSFGETTTARLGETPLVSARVRADMGWLLALVKDLEGAPE
                     VLGRLSVSMNAMAHRVGDRLVLPSSDVHGNADRRSVRVRHTSPLSHIRRLAPAAAPVPY
                     AEVVAELTDRFPAVGHEQISAFVAELVGLGLLVTDLRPPVTDPCPEAYVLARLTAAGVE
                     HPAVAGLREVVDMTRTAVHDDTGALDRLRLTQRTLVPAYRHQPFQVDSALGLVDTAINR
                     QVADEVAEAVGCLARLGRAAPGGYDHLSPYHEAFMERYGSDALVPVLELLSAERGLDAP
                     NSYLNPPRAMVMHQTGGEGDPRTARALVALASQAWRSGADEVELSDEALRRLVPADEGD
                     TRRGCPGVDAYVQIAASSARAIDDGDWRAVLNSDGLGEGGRTFGRFFHLLGPSAAERLR
                     SYARAREALEPDVVVAELAYLPGNGRGANVAIRPAVHGYEIPVNVAPSAAPDRTIDLSD
                     IHVGATDDGLRLYSARLGRELVVVQNHMLSPLGAPNVCRFLLEVSRARYAIPTGFTWGP
                     VEGAPYLPRVVRGRVVVRAAEWNLYPAGAQAPLDTAPVPVPRTAAELTEWRRTWGVPRH
                     VYLADDDNRLLLDLDHPACADELLADLRAADERVTLQEALPDPDRTWLRDSAGRGHLAE
                     VVIPLLAAPAGTEAAPPPDAAPAREAAAEGIRRKARPAAHPSHLPGSEWAYLKLYAARD
                     LHDEIAAVELAGLVKEIRDAGADVDRWFYIRYADPDAHLRIRTRTPAGGTSALEPLLDW
                     GRSLVRRGIAERLEVATYHPEVSRYGGPAVYDHIEEFFAANSAVSAQLLGLLWDKEPGL
                     TAEAVTLAAVDALYAQWGLDVRERLAAMPRPAEDKGAREQYKKDRDYLCELLAPWDRRP
                     HLRGRAHHERLAPVLAGQVDAVRRASRAVADAEAAGTLWGTRDAVLASLAHMQVNRLLP
                     MDRPAEDRCYLVWGHVLNCLRGRPRD"
     aSDomain        complement(12443..12718)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AOB60_RS18785_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.30E-17"
                     /identifier="RREFam001.1"
                     /label="AOB60_RS18785"
                     /locus_tag="AOB60_RS18785"
                     /protein_end="261"
                     /protein_start="169"
                     /score="52.7"
                     /tool="antismash"
                     /translation="VSMNAMAHRVGDRLVLPSSDVHGNADRRSVRVRHTSPLSHIRRLA
                     PAAAPVPYAEVVAELTDRFPAVGHEQISAFVAELVGLGLLVTDLRPP"
     gene            complement(13222..14475)
                     /locus_tag="AOB60_RS18790"
                     /old_locus_tag="AOB60_18050"
     CDS             complement(13222..14475)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="AOB60_RS18790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18050"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_102924121.1"
                     /sec_met_domain="LANC_like (E-value: 1.2e-37, bitscore:
                     127.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPSPLLPTGLAARANAVASVIRERLDSPAGADAHAARAAGQSEV
                     SFWNGASLSEGHAGLALLHLHAARTAERDAEGERSRDRAFSFVRAAFAATQEDALTHPG
                     LFDGTAGLAFALREVAADEPRFLPSLAALDEQLSRQVLAMELPRRPGAVAAHHYDLVYG
                     CAGVLAHLCHVRPATPLVEQALQRCLRYLLWVGADQRWAVEGRLDTGMSHGAAGIAAAL
                     ATAWRHGHRLPGQRLVLDRLVAWLLEVGSRGGRQLQWPRSVPVAPHPDDGDEAVPAWCH
                     GTGGVAAGLLTVADATGDRALEARAFAALDGLLDRVAAGDVPRSPTVCHGLAGCVALAH
                     EFAARGSEGAARGLARLVAELLNAAEPERALVYRDRETTGHVVDNPGLLTGAAGVSLTL
                     RAVATGRRPSWWRVLFLR"
     gene            complement(14565..14747)
                     /locus_tag="AOB60_RS18795"
                     /old_locus_tag="AOB60_18055"
     CDS             complement(14565..14747)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AOB60_RS18795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AOB60_18055"
                     /product="hypothetical protein"
                     /protein_id="WP_073442311.1"
                     /transl_table=11
                     /translation="MDEFDLDARVIVSADPAQTSLSPVASVASRVASKWAVKQTIRQTI
                     KMTAACAAVRTNGKC"
     misc_feature    complement(14749..14763)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.53"
                     /tool="antismash"
     misc_feature    complement(14833..14847)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.09"
                     /tool="antismash"
     misc_feature    14834..14847
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.47"
                     /tool="antismash"
     misc_feature    complement(14834..14849)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.5"
                     /tool="antismash"
     gene            complement(14940..15524)
                     /locus_tag="AOB60_RS18800"
                     /old_locus_tag="AOB60_18060"
     CDS             complement(14940..15524)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237369.1"
                     /locus_tag="AOB60_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18060"
                     /product="hypothetical protein"
                     /protein_id="WP_102924122.1"
                     /transl_table=11
                     /translation="MWQPDDILMTQKIAPLVNRYVFTLPESGEVIAFAEQKRFALQEQL
                     TLWTDEGRSREIGGFKAREVIDLGATYDVTGPGGDLVGSFRKDFKASFLRSTWHLTQGE
                     KGAAVGKERRVGVALARRMWDVVDLVVPLVTLPPVPFVYHFDFVRDGRPVLAVERKWGI
                     RDRYVIRIQDPGLDRTLALCMAVGLDALQGR"
     gene            complement(15714..17093)
                     /locus_tag="AOB60_RS18805"
                     /old_locus_tag="AOB60_18065"
     CDS             complement(15714..17093)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088364.1"
                     /locus_tag="AOB60_RS18805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18065"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_102924123.1"
                     /transl_table=11
                     /translation="MTRTTTPHHTDKALETQGAYGARERREPTPTSAARARTVLISGAS
                     IAGPALAHWLARYGYRPTVVESAPALRGGGFAVDFRGAAHLAALQKMGVLEEIRRRRTG
                     GSSLTFIDARGNHVAALPPEFAGGDVEILRSELSRILYDHSCPTPTPHDDTAAPAAVAG
                     TTAYLFGDSLTSLTETADGVHVTFEHAPPRTFDLVIGADGLHSTVRRLAFGPEADFVSH
                     LGYYVAGWDLPHGAAPDLAAHAVGYNEPGRLVTVGRVPRRADDPSYGGEAFCVFASERL
                     GHDRRDPQAQREALVQAYEGAGWRTTELVGTVRDADDLYFDAISRVDVPTWSRGRIALL
                     GDAAYGATVGGMGTGSAIVGAYVLAGELALAAGDHRRAFARYEQKLRPYVSRCQEGGRG
                     TGAFLAPLTQEAIAARNSALNDPAALTAMLQEGHDISADISLDDYPSLVHDDTRSDRKG
                     S"
     gene            17192..17941
                     /locus_tag="AOB60_RS18810"
                     /old_locus_tag="AOB60_18070"
     CDS             17192..17941
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088365.1"
                     /locus_tag="AOB60_RS18810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18070"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_073442313.1"
                     /transl_table=11
                     /translation="MAGDEKSSAFGDQAGSVELLWGGRERPSRGPKPALSLERITRTAI
                     GLADTGGLGAVSMQRVAAELDFTKMSLYRYVPGKAELVALMIDTAMGEPPEPAGAAAGD
                     WRGALRDWAQRLAAVFAQHPWLLSALVGPRVMGPNELGWTERALAALAGTGLTGGEQLD
                     AVLVVSGHVRAIAQVSASMGVGGAPAKEPEAALSAALNELLVGRSERFPALSAALAGTA
                     GGESREQAWEFGLERILDGLEAYAGRG"
     gene            complement(18014..19189)
                     /locus_tag="AOB60_RS18815"
                     /old_locus_tag="AOB60_18075"
     CDS             complement(18014..19189)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000902 - cell morphogenesis [Evidence
                     IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541960.1"
                     /locus_tag="AOB60_RS18815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18075"
                     /product="rod shape-determining protein"
                     /protein_id="WP_073442314.1"
                     /transl_table=11
                     /translation="MASSTSSGTYDIGIDLGTANTLVYARGKGVVLNEPSVVAVNAAGD
                     VVAVGSEAKRTIGRTPSGITAMRPLREGVIADFDAAEQMLRALMKKALPSRRFSRPRVV
                     ICVPSGITGVERRAVIDSARGAGAREVHLIEEPMAAAIGAGLPVAEPVGCMVVDIGGGT
                     TEVAVVSMGGLVTAQSVRVAGDAMDAAISTYIKKEHGLAIGERTAEDIKIAIGSAVWTP
                     DDDRPLPTRLTVGAASDSVSDPASDAETDAESLADRAARPSPHSYTVRGRDHLSGLPRL
                     QEITAEEIRAALAEPVEAIVRAVHNTLDDCPPELSGDIIERGIALTGGGALLRGLDRRL
                     REEMGVPVVVADAPLDCVVNGTAKCVDEFATLHGLLTGAKEQPRKNVRLGM"
     misc_feature    complement(19242..19262)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.04"
                     /tool="antismash"
     misc_feature    19262..19277
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(19353..21419)
                     /locus_tag="AOB60_RS18820"
                     /old_locus_tag="AOB60_18080"
     CDS             complement(19353..21419)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541961.1"
                     /locus_tag="AOB60_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18080"
                     /product="FUSC family protein"
                     /protein_id="WP_073442315.1"
                     /transl_table=11
                     /translation="MTWSRALKEATRSGLTIERAKLTPLIAIRGTVGVAIVLGLCLWRG
                     NPALAVSSAFGAFSAGIVTFQRSMRPRPVLALAVAGALAISTFLGYLAAAHVVWFVLLL
                     TGWTLLAGMAWAIGPVSGLVGTQTVAIMLITVTLPTSVLGALEHAALIACGGLVQAALI
                     VLFPVRPWGIQRDTLADALAAEADYARRLRHDPVAPFDPAPLMDARAAATVTPRQARRR
                     PVQLHGPRGLAERVRPVLASLADPVVGAPLEGPERDRARELLGAAATVLDAVAHAVRHA
                     SPVRLPPEAVAALEVPASGPMLRGPARRTAYRLISLLADAVELTDEPVEATRPTTEAER
                     GHLLRPSVPRLVPVALRALRREARWSSHVLRHALRVAAVAVAGYLLGAALHFGHGYWAP
                     LASVMVMRPDFAQTYSRGVARFAGTVVGVTLAGALMALAHPGAYVSAALALLCVFLMYL
                     LMRTGFSVTSACIAAYVVFLLGIVGAGWEQTVQERLVLTLVGGVLAMLSYALFPAWETP
                     RLRDRLADWLTTNGRYALAVVDGYARPAERRPRQVRDALLDARAARAAWEATEARAEKE
                     PVRHRGLPLGGAHAASAALATMGRVTMILEAHPPDRDARPSPGAAAFAAALRPALDRAA
                     RAVRDGEAMDWGEPHAAWERWSAEGEHEGVAVRATELLLDALDDLAEALPPDP"
     gene            21860..22882
                     /locus_tag="AOB60_RS18825"
                     /old_locus_tag="AOB60_18085"
     CDS             21860..22882
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571347.1"
                     /locus_tag="AOB60_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18085"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_039636301.1"
                     /transl_table=11
                     /translation="MRKSLFKPVIALIALTVLGTTAGCGTSDDSQGAPVRFSGPRSGAA
                     MQTAPADKNSLVQMPTHPINFQETSKVGGAGGNTPIAVTTYHGKKSGFTGKVWVWAPPE
                     YYEKKNANKGFPVMEALPGAYGYPVNYWIGSDLKLEESLATWSKAGKSLPFIVVMPVLN
                     PNDKQYYDGSDIPGQPKIGTWLSKDVPDLVRENFRTLKTRNAWCIMGSSSGGFSALKNV
                     LQNPNDFKVAIPNGPDIVPDSPLWRGHLKEMRENNPEVLARQLNAHGGPDVYLAFQDGS
                     KEYTVLPKVRKFLAQYGHGHVKTRLQIVPNGTHSGQTYVTGLGMGTMQWVSAHMQGPTG
                     "
     gene            complement(22964..23401)
                     /locus_tag="AOB60_RS18830"
                     /old_locus_tag="AOB60_18090"
     CDS             complement(22964..23401)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571346.1"
                     /locus_tag="AOB60_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18090"
                     /product="hypothetical protein"
                     /protein_id="WP_102924124.1"
                     /transl_table=11
                     /translation="MSRTASRPVTAVAACAAALGLTLAATAPAAATVRSDPAGRHTAAE
                     IHRFLTGFYGQHGPTPHQRAHQVSDYLKDRAAHTDGYDLLLCAQNTPRAITVGTVTTAQ
                     SAGVGWATVTTGWDGGATRSFTAYVRLESHPIMLQDVDCGQ"
     misc_feature    complement(23395..23405)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(23550..24410)
                     /locus_tag="AOB60_RS18835"
                     /old_locus_tag="AOB60_18095"
     CDS             complement(23550..24410)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088370.1"
                     /locus_tag="AOB60_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AOB60_18095"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_073442317.1"
                     /transl_table=11
                     /translation="MTATTPAAAPGYRARRTLPLRVEARRQLRRRRTLVIGAILTLLPF
                     VLVAAFAIGGDPSTRNSGRISLMTTATASGANFAATALFVSAGFLLVVPVALFCGDTVA
                     SEASWASLRYLLAAPVPRARLLLSKLTVGLVFSAAAMLLLPLVALAVGTAAYGWGPLQL
                     PTGGALAPGDAVLRLALVTGYVFVSQLVTAALAFWLSTVTDAPLGAVGGAVGLTIVGNV
                     LDQVTALGDWRAVLPAHWQYAWADALQPQLEWSGMLQGASVSVSYALVLVALAFRGFAR
                     KDVVS"
ORIGIN
        1 cccgccgcgc cccaccgggc acccacttgt acccgggtcc gcagtccgcg agcccgtctt
       61 caagaccccc gtcgtcaccg cccccggtgc tgtgtccgac ctcgcggtcc accccttccc
      121 cgccgaccgc cgcccgttct cccctcccct gggccgcacg cccacgggcc gacgccccac
      181 ccatgccccg cgctccacgc accccagcag ccccaacaaa cacaccgctc ccaccgtcaa
      241 tggccacctc tgcaagcgca cccgcccccg cccccgcatc cacatccgca tccaccgcgc
      301 acaacagcag gccgtccgga ccagtggcgg cgcccgcagc ccgcgcgcca ctgcgctgct
      361 ccccaccccg caccctccgc gcgatcaccc cgtcatccca ggcgccctcg ataccggcgc
      421 cctcgatacc ggcatcgtcg tcccgcacca gcccctcccc gccctcgtcg atccccgtcc
      481 cggcccgtcg ctccccggac tccgtcaccc cgtcaccgcc tctctcccgc accggtccgc
      541 cgtcgcgcgc ccgcgctccc gttcggtccg ccgctccgtc tcccacgcct ccaccggccg
      601 cctccgacgc tgctcgcgct gcaccaccga cagcgcggcg atcagttcgg cctgttggtc
      661 cggcggcacc gtcagccggt ccaacggggc cagccggcgc tcccgttcac cgtcgagggc
      721 gtgctccaga tacctggtca gcagcctggc gccctggtcg cacagccgca gcgcgctctg
      781 cgcccccaag aggtcggcga ggttctcgcc cgccgtacgg gcccggcgcc cgcccagcag
      841 ggccgtggcc agcaacgccg tcggttgctc cccgtccacc gggtcgctcc gttcaccggc
      901 cgagccacca cgcgtctccc gggtctcctc ttccgcgagt tcctccaagc agcgccgcca
      961 gcgccggacg atcacaccga tccggccggc ggcgcccgcg gcaccgtccg ccgcggccgg
     1021 cgccatctcg gccgccgcgg gatcccgccg ccaggcgccc gcggcccgct cgtcggcctc
     1081 ctcgacggcg cagaccagca acgcggtgag ccctcgggtc agcgcgtcca gcagttcgtc
     1141 ggcgcgcccg ccgggcccgt gcgcctgcca gtgggcgcgg gcgtcgccgg ccaggacctc
     1201 accggccgcg acctcgcgcc gcacccgctc ggcggcctcc tcgtacgcct cctcgacgcg
     1261 gccggccagc cgcagtgccg cggcgtgctg cgcggcggcg gccccggcca gcgcgggcat
     1321 ccggctgcgc agcgaggcga tcgcgccggt ggcggtccgg tccgcggcgg cactacgggc
     1381 ggcggggtcc agggcgtggc gttcgagcca gtcgcgcagg ccggcgaccg ccgtggcggg
     1441 cagcagtccg cggcccccgc ccgcggactc gggcagctcg ggaatggtga agcggggtac
     1501 gtggccgagc ccggcgcgct gcaggagctc cgcgtaccgc gcggagatct cggcggcgat
     1561 ctggtgcggc acccggtcca ggacggtgac cagcgtgacg tcgtattcct tcgcggtgcg
     1621 cagcaggtgc cagggcaccg catcggcgta ccgggcggcc gtggtgacca gcacccagac
     1681 gtcagccgcg cagatcaact cggcggccag ttcgcgattg cctgccacca gcgagtcgat
     1741 gtccggggcg tccagcagcg ccaggccgct gggcagcgcg gggtccgtct cgatccgcac
     1801 ggtcggcgtc cccggctccc ccgccgcccg tccacgcccc ccgccgaggc ccttctcgcc
     1861 cccctcccct cgtccccctc cgtcgtcccg ctcgtcgccc tcgccaccgt cctgctcggg
     1921 cacccacacc cgggtgagcc ccggcagcac ccgctgcccg gcgaaccagc ggtggtcgtc
     1981 ggggtggcag accagcaccg gcgtacgcgt cgtgggccgc agcaccccgg cctccgagac
     2041 ccgtcgcccc accagcgaat tgaccagggt ggacttgccc gcccccgtgg agcctccgac
     2101 gaccgcgaga agaggggcct taggggcgca caggcggggc atcacatagt catccagctg
     2161 ggagagcagc tccgcccggt cgcgccgggc gcgagcggcg cccccgagcg gcagggggaa
     2221 tcgtgcggcg tcgacacggt cacgcagaac ggacagtgcg tcgatcagcc ggggtcctac
     2281 gtccaaggtc gccacatgtg aagaatgccc aatttcgtta gctttttgaa gcgtatagac
     2341 ccttgcgtgc gccgcgaggg cccttaagga acgagatagg tgccaaatgg gattttcgta
     2401 acatccaaga cgcaggcata acgagtgcac aacacccgcc gcacgagacg tcaaaagccg
     2461 tgcaggattc gtacctgcct gcgattatcg ggatcgcttc accgaacctc cacaacgtgc
     2521 cacggaggtg aagcaaccgg gacgaggcac ccgggcctct atcctggtcc gcggtcgtga
     2581 tccacgccga ccacccggcc cccgtagctc agtggataga gcaggtgcct tctaagcact
     2641 tggccgcagg ttcgagtcct gccgggggcg ccaggccaga ccctccttcg ggagggtctt
     2701 tttgctggtc agcgcggtgt ggtgtggcgc gccgaggtct ccggggtgcg tatgggttgc
     2761 ggcctcaggg ggctgttcct gccgcgtacg ctccgcgctc gcgagaagtc gttaggtccg
     2821 ggcgtgcagg agactgtcgt atcggggctg ccggcttggc gcaggttcga gccctgcgtg
     2881 gggcgcaccg cagagtggaa ccgttcggtt cgtttccaca ggtcatctgg tctacggggc
     2941 ggttgaaagg cccgggtggt gtgtgtgggc ataaacccga ggggacccgc ggcacggtaa
     3001 ctcagggcag ccgccggcta cttggaggcg ggggcttcgt cgcttcctcg cgtccgggct
     3061 gcggttcggg cgtccgcgta tgcgatgtac tcgcacttgg ggaaggggcg ggtatccggc
     3121 aggctcgaaa cgcggtcatg gggcatgggg catggcgata tccggggccg gcggttgcgg
     3181 cgcgcagtcg caggggccga cgcaacgccc tggatgccgg tggtgatccg ttcggccccg
     3241 gcctccaggc tggaatgtca cgccgctcat ccaaacggaa gcggcaatga cggcgacccc
     3301 agtcggccga tggggtggcc agttaactgc caggcccaaa aatgaattac tggatatgga
     3361 taaccgcgac gtcgggtcgg ccgagtcgag tcggttcgcc gcgccgtcct cggccccgcc
     3421 cgaccctctt ccgcgaagca cgctgcctcg gcgccctccg ggatgcgggg gtggccacca
     3481 gccgggaagt agtccgggca ggggtctggt ccgggtaggt accggcggtc ttcgcggctg
     3541 cgtgcgatgg ttcggttgcg gatcggggtg ggtaaggccg gaatctgagg gattttcgca
     3601 atcttctaga atgcgggatg gaagattctc gaggtttccc gggaccgtcc cggctcttca
     3661 gtcggccgcg ggcatgggca tgggcagggg catcgcaacc gagaatccgt ggatccggat
     3721 gtctttggcc cgtgaaaacg gggagcacca atgagcacta ccgggcgcag gtcgttcttg
     3781 cgtggcagag gcttcttccg gggcaggtct tggttccggg gcggagactg gttccggggc
     3841 ggagacttct ttcgttttcg tggtgagggg gtgtggggga atgggggttc ccgccgggcc
     3901 gcgctcgttg tcgacggggt ggtcatcgcg gcggctgcca cggagttgct gactctctac
     3961 gatgcgctcg acgccctctc ggcgctcgtg tgcccgccgt cactgttcgc gctggtgctg
     4021 cgccgccgct tcccggtggc cgtgttgttc gccaccttgc cttccatggc caccggccat
     4081 ctgtggctgg ctcccatgat cgccatgttc acggtggcgt ccaggaccgc ccgccgtgcc
     4141 gtcgtcggcg tcgcgacggc cgcgctgttc gcggcgacca tgtggtccgg gtacgacctc
     4201 gacggcgggg cggtggactg gagccaccat ctgttcctgg tcgaggtggc tctcatgttc
     4261 agcgtcggcc ccgccgggct cgggctgctc tttcgcaccc gctccgagct gcgggccagg
     4321 ctcgcggacc tgatcgcctc ccaggcgcac ggccgccgcc tggaagccga gcgggccgtg
     4381 gcgaaggagc gcacccgtat ggcccgcgag atgcacgaca gcgtttcgta ccacctgggc
     4441 atcatcgccg cgcagtccgg cgccctgtgg gcgaccgccc ccgacgacac cgtccggcgg
     4501 gatgccgaga ccatacgccg tcacagcgcc gacgccatgg cggagctgcg ggagatcgtc
     4561 ggcgttctgc ggcacgggcc gagccgggcg gacgggacgg acgcccggct ccgcaacgtg
     4621 ccgaccctgg tggaggaagc ccgcctggac gcgacgctcg actgtggtgc tctggagacc
     4681 cacaccatcg ccccctccgt ggaacgagcc gcctatcgaa cggtccagga ggcgctcacc
     4741 aacgtccgca agcacgctcc cggtgccccg gtcgccgcct ccgtacgccc ctcagcccgg
     4801 ggcgacctgc tcgtcgtcga ggtccgtaac cagccggcac cccggacacc tccgcaggtc
     4861 gcccccgtgc tcgacgtgcc cgcgagcggc tacggcctcg cggggttgag ggaacgcgtc
     4921 actctcgtcg gcggcgcgtt ccgggcggag gccactgcgg acggcgggtt cgtggtacgt
     4981 gccgagttgc cgctcgggcc tgccgctccc cgcgcggcgg ggccggcgcc gggccatcag
     5041 cccgcgaccg ccgcccaggg cgagtcgggg tcccgctcgt agaccgacac gtgccgcagg
     5101 ctggcggagg tgtacggggt accgcaccag tcctccatgc gctcgacgag ccgtagcccg
     5161 gacagctcgg ccagcagatc gatctcgaag gggaaggcgt agcgcagtac gtgctcacgg
     5221 gtggccgggg ctccgccgtc gatgatggtg tgcgtcgaga gcatgagctg ttgcgagcgg
     5281 tccacggcga gcgtgtccag catgacggcc tgctcgtcga ggtggcgcat cgagaagtcc
     5341 ggcttctcca ggtggtggta cggcgccggg tcgaacgcct ccaggacgaa ccggccctcg
     5401 ggtgcgagct gttcgtggac cagtcgcaga gtgccgagct gctgttcctt cgtgatcgcg
     5461 acgaagaagg tgttcagcag cagggtcaca gtgtcgaaga cacctccggt gccttcttcg
     5521 gtgaagtcac cgaactgggt ggtcaccgcg gtctgcgggt tctgcctgtg gagctcgtcc
     5581 agcatggcct cggagccgtc gatgccatgg acccggaagc cgcgctcggc gagcgggacc
     5641 gcgatccggc cggtgccgac gcccagttcc aggatgcgcc cgtcgggcgg cgtacggccg
     5701 gcgacgaact cgaccgcctg ggcggtgtcg tggtcgatcg gatacatgcg gtcgtagacg
     5761 ctcgccagct tctggtcgta gagcgcgttg ccgagggcca tggtggttca actccaaacg
     5821 gcggggtgga cgggcggggg ggaagagttc ggaagccggc ccgccgccgt tcaggcgttc
     5881 agcgggtctc ggccagggcc gacggacgca ggttgccttc cgcggcggcg cggtgtgccg
     5941 ccacggcagc ctggacgcga ttggccagcc ccagtttcgt caggatcgag ctgacgtgct
     6001 cctttgccgt cgacgcgctc agcagcagcc ggcgcccgat gtccgcgttg gtcaggccct
     6061 cccccagcag ttcgagcacc tgctgctccc gctcggtgag cgtgtccagg cgcgggtccc
     6121 gcccgccgtg gcgcggaccg gcgccgaggt agccgtcgac gacgatgcgt gctgcggccg
     6181 gggagagcac ggttccgccc gaggccaaca cccggactgc gtcggcgagt tcctgcggtg
     6241 tcgcgtcctt cagcaggaag cctgccgcac ccgagcgcag cgcggccgcg atgtcctcgt
     6301 cccgcaggaa cgtcgtgagg acggcgaccg cgggcgggtc ctggtgggcc cggatccctt
     6361 cgagggcggt gagtccgtcg acctccggca tgcgcaggtc gagcaggacc acgtcgggcc
     6421 ggtgggccgc cacggcttcg cggacctccc gcccgtcgca ggcgaccggc acttcgatgt
     6481 ccgcttcgct ctccagaatg cgctgcatgc acgaccgcag cagaatttca tcgtcgacga
     6541 tcatcacccg gatcatccac gccccccgtc agagcagccc taatcggtca aacctcgttc
     6601 aaggtaccaa cagacaaggg attcgagagc gcgggggccg gaaagggagc gcgatggaaa
     6661 tggttttcga cgtgatatcg cggagcggat cagacgggct cggagaggtg ctccgtgatg
     6721 agctccacca gcttcgcgtc ccacgtggag acgagcagtt cgatcttctt cgcggagccg
     6781 tcctcggccg tcacggtgca gtccagggcc gtgccgaagc gcccgccgcc ggtcgccgcg
     6841 gcggccggac cggaaagcgc cagtgctctg gggccgggcc cgtccaggac gaccccggac
     6901 gcactcacca cgattctccc gcgatgcatg gcggggcctt gtgcccgaat tcggaaccgg
     6961 cagcgcagcg tgatcctttc accgcgccga aaggcggcaa tgcgacgcgc tgaacgtgcc
     7021 ctgtcaagac tcttgccgcc tatccagaac accgtgtcca tcagagaaaa caggacgaat
     7081 tccagaagca tgtgattgcc cctcaactca acttgggatg gctgctcgta caaaacccgg
     7141 ggccctcatc ggcccggggc acggcccggt cctgcatcgc ccccacgatg gcccgcacgt
     7201 cggccagtgc ggcgtcgagc ccttcggtca gcaggacccc cgcacagctc agcgcgatct
     7261 ccgtggcccc cgcctcaccg taaccggtga gctggtccgc cagctcgtca ggggtgccgt
     7321 aggcgaagac cccgctgtcg accagtacgc cggccccggc ccacgggtcg gccgcgtcca
     7381 cgccgaggcc cgccgagcgg agcatcgccg cgtagtgctc accgcccagg tgcagctcgt
     7441 gcgccgcgaa cgcgagccgg cgcgggtccc ggccgggcct gcgcaccgcg cacggcacga
     7501 tcgacgtcac cccggggacc gccctgtccc gggaggcggc gccgcgcgcg agcgcaggca
     7561 cgatccggtc cctgaggtag ctggccggcg tcagcagggt gatcgccacg tcggcgacct
     7621 ggcccgccgt gtacgccatg cgcggccgca gcacgccgac accgagcgag acgggagggt
     7681 gggggacctg ggggagcccc tcgtccacac gcacatagcg cccctggaag tccaccaact
     7741 cgccgtccag gagccgtcgc acgacggtca ggtactcggc gacggcggtg cgcggactgt
     7801 cgtacggtgc gccgcgcagc gccgtcacga acgccgggtc gcccgtgctg tagccggcga
     7861 cgacgtcggc gccggtcagc agggccagcg acctggcctg tatcgccgcg tccagcgggt
     7921 ggcgcagagc cgtcagggcc acgctggtgc cgaccggcac gcggatgccg cgcccggcga
     7981 ggtgcgcgaa ggcatggtgg gtgtcgacca gcaccgactg ccccatgtag agccgctcca
     8041 gggacagctc ccggacgact tcgccgaagg cggtgaggtg gtccaggtcg tacgccatga
     8101 gcgggtacat gagggacagc gggggtgttc gggtcatggg tgcttcctgt gcggcggcgg
     8161 tcatgcggag gctcccggca ggtaggcgtc ggcctggagc cggaagaggt gggcgtacgt
     8221 cccgccgcgt gcgagcagtt cctcgtgggt gccctcttcg atgagcgcac cgccctccac
     8281 gaccaggatc ttgtcggcga tgcggacggt ggagaaccgg tgggagatca ccagggacgt
     8341 cgcccgggag cagatcgtgc gcagccggcc gaagatgtcg gcctcggcct cggcgtcgat
     8401 cgcggcggtt ggctcgtcga ggatcgcgat cggcgcgtcc cgcaggaagg cccgcgccag
     8461 ggcgatcttc tgccactggc cgccggacag ctggtggccg ccctcgaagt gccgtcccag
     8521 ggtggtgtcg taggtgtccg cgagacggtc gatgaactcg gcggcgccgc tggacccggc
     8581 cgctgtgcgg aggcgggcgt cgtcgtcgag gtgttcgagg cggccgaagc cgatgttgtg
     8641 ccggacgggc atctcgtagc ggatgaagtc ctggaagacg acgccgatgt tccgctggag
     8701 gtcgtcggtg tcgtactcct ccaggggcac gccgtcgacg aggatgcggc cgctggtcgg
     8761 ctcgtagagg cgggagagca gtttgacgat ggtgctcttg cccgcgccgt tcgcgccgac
     8821 gatcgcgcag caggtgtcgg cggggatgaa gcaactgaac cggtcgaggg cggtggtcgt
     8881 ggtgccgggg tagcggaagg tgacgtcctg gaactcgatg ccgtgcgtca ggcgccgcgg
     8941 gaagggccgg gtgccgcccg tgatgcgccc gtcgggcagc gtcagatagt cgaagaggtt
     9001 ccccgtgaac agcgtgttct ggtacagggt ggccacgccg agaagcagcc cggtggccgc
     9061 cgcgtgcacc gcgcccagcg cctggaggta cccggcgagc tcgccgatcc ggccgttgtc
     9121 cgcggtggat ctgagggcga agaccagcgc gcccgccgag cagcccacgc tgaccaggcc
     9181 gagcgccgcc gaccagccgt gccggcggcg tgccagcgcc cggtcgacgc ggaagaactc
     9241 ctgcacgagg gaccggtagc ggcccacgag gtgggggccg agctggtaca gcttcacctc
     9301 cttgtaggag gagtccgtcg tcgtcaggtc ctggtagtag aaggcgcggc gccggtcctg
     9361 cgcacggtgg tactcgatcg cgtagccctg cttgctgaac accacgtgcg cggcgagcgc
     9421 gggcaacggc gccagcagga tggccagggc gatccagacg ttccaggaga acagcaccca
     9481 gctgaccatc accagtgatg ccagcgcggt gagcgtgcgc atcatctcct cgaacacctc
     9541 gaaggcggtg ccgctgccgc tctcccgcag cgcccgctgc agccggtcgt acgcctcggg
     9601 gtcctcgtag gcgctgaggt ccatgcgggt gcccttgacc atgacccgct caccgatctt
     9661 ggccgtgaac tccaactgga gcagggagtt caggtactgc gagagggacg tcaggatgtg
     9721 ctccgccacc gcgaccgcga cgagaccggc cgcggcgcag gtgagccggt ccatggcgtc
     9781 cggcacccgc gtgagggcgt cgacgacggc ctgcacggcc ctggcggtca gccagattcc
     9841 ggtggccggc acggcggcgg tgagtaccgt ggccacggcg agcgcggaga ccctcagggg
     9901 gctgagtccc cagaacgtgc gcaggacgag ccaccagtag cgcaggtccc gggagaggcg
     9961 ccggtgctcc tcgggcacgg cctggtccct ggcttcctga tcagtcacgg ggcctccccc
    10021 gcaggcagtt caggacgtgc ccccagacca ggtagcagcg gtcctcggcg gggcggtcca
    10081 tgggcagcag ccggttcacc tgcatgtgcg cgaggctggc caggacggcg tcccgggtgc
    10141 cccacagcgt tccggccgcc tccgcgtccg cgacggcccg cgaggcccgg cggacggcgt
    10201 cgacctggcc ggcgagaacc ggggcgagac gctcgtggtg ggcgcggccc cgcaggtgcg
    10261 ggcggcggtc ccagggggcg agcagctcgc acagatagtc gcggtccttc ttgtactgct
    10321 cgcgggctcc cttgtcctcg gcgggccggg gcatggcggc gagacgctcg cggacgtcga
    10381 gaccccactg ggcgtacagc gcgtcgacgg ccgccagggt gaccgcttcg gcggtgagtc
    10441 cgggctcctt gtcccagagg agaccgagca gttgggcgga gacggcgctg ttcgccgcga
    10501 agaactcctc gatgtggtcg tacacggcgg gaccgccgta ccggctcacc tcggggtggt
    10561 acgtggcgac ctccaggcgc tcggcgatcc cccgccggac gagggagcgc ccccagtcca
    10621 ggagcggttc cagggcggac gtgccgccgg ccggtgtccg ggtcctgatg cgcaggtgcg
    10681 catcggggtc ggcgtaccgg atgtagaacc accggtcgac gtcggcgcct gcgtcccgta
    10741 tctccttgac gagtccggcc agttcgaccg cggcgatctc gtcgtgcagg tcacgggcgg
    10801 cgtacaactt gaggtacgcc cactcggagc cgggcagatg gctggggtgg gcggcgggac
    10861 gggccttgcg tcgtatcccc tccgccgcgg cctcgcgggc cggcgccgca tccggtggcg
    10921 gcgcggcctc ggtgccggcg ggcgcggcca ggagcggaat gacgacctcg gcgaggtgcc
    10981 cgcgtccggc gctgtcgcgc agccaggtcc tgtcgggatc cggcagcgcc tcctggagcg
    11041 tgacccgctc gtcggccgcc cgcagatcgg ccaacagctc gtccgcgcag gccgggtggt
    11101 cgaggtccag gagcagccgg ttgtcgtcgt cggccaggta gacgtggcgg ggaacgcccc
    11161 aggtgcggcg ccactccgtc aactctgcgg cggtgcgcgg tacggggacg ggagcggtgt
    11221 ccagcggggc ctgcgcgccg gccgggtaca ggttccactc ggcggcccgt acgacgaccc
    11281 ggccccgcac gacgcgcggc aggtacgggg cgccctcgac cgggccccag gtgaagccgg
    11341 tggggatcgc gtacctggcg cgcgaaacct ccagcaggaa ccggcacacg ttgggtgcgc
    11401 cgagcgggct gagcatgtgg ttctggacga ccaccagttc gcgcccgagg cgtgccgagt
    11461 agagccgcag gccgtcgtcg gtcgcgccga catggatgtc ggagaggtcg atggtccggt
    11521 ccggggcggc ggagggtgcg acgttgacgg ggatctcgta gccgtggacg gcgggccgga
    11581 tcgccacgtt ggcgccgcgc ccgttgccgg gcaggtacgc cagctcggcg acgacgacgt
    11641 cgggctccag ggcttcccgg gcacgggcgt aggagcggag gcgttcggcg gcggagggcc
    11701 cgaggaggtg gaagaaccgt ccgaaggtgc gtccgccctc gccgagaccg tcgctgttga
    11761 gcacggcgcg ccagtcgccg tcgtcgatcg cacgggcact ggatgcggcg atctggacgt
    11821 acgcgtcgac gccggggcac ccgcgccggg tatcgccctc gtccgcgggg acgagcctgc
    11881 gcagcgcctc gtcgctcagc tcgacctcgt cggctccgct ccgccacgcc tgggaggcca
    11941 gggcgaccag ggcccgcgcg gtccgcgggt ctccttcgcc gccggtctgg tgcatgacca
    12001 tggcgcgggg tggattgagg tagctgttgg gggcgtcgag gccgcgctcg gcgctgagaa
    12061 gttcgaggac ggggacgagc gcgtcgcttc cgtaccgctc catgaacgcc tcgtgatacg
    12121 gcgagaggtg gtcgtatccg ccgggcgccg cccgacccag ccgggccagg cagccgacgg
    12181 cctcggcgac ctcgtcggcg acctggcggt tgatggccgt atcgacgagg ccgagggcgg
    12241 agtcgacctg gaagggctgg tgccggtatg cggggacgag ggtgcgttgg gtcaggcgca
    12301 gcctgtcgag cgcgccggtg tcgtcgtgga cggcggtccg ggtcatgtcg acgacctcgc
    12361 gcagtccggc cacggcgggg tgctccaccc cggcggcggt gagccgggcc aggacgtacg
    12421 cctccgggca gggatcggtg acgggtggcc gcaggtcggt gacgagcagc ccgaggccga
    12481 ccagttcggc gacgaacgcg gagatctgct cgtgcccgac ggccgggaac cggtcggtga
    12541 gttcggcgac cacctcggca tacgggacgg gcgcggcggc cggggcgagg cgccggatgt
    12601 ggctgagcgg gctggtgtgc cgtacccgca ccgatcgccg atcggcgttg ccgtgcacat
    12661 ccgaggaagg caggacgagc cggtcaccca cccggtgcgc catggcgttc atggacacgc
    12721 tgagccgccc gagcacctcc ggcgcgccct ccaggtcctt caccagagcg agcagccatc
    12781 ccatgtcggc ccgcacccgg gcggacacca ggggggtctc gccgagccgg gcggtggtgg
    12841 tctcgccgaa ggagccgagt gcgacgccgg agaaggcccc gaagggggtg gggcgggtgc
    12901 tcatgcgggt gaggtagcgc agggcccggg agtggacgcg ccgcatctcc ttgccgctcg
    12961 cgcgtccctg tgcggcctcg accttggcca gcccgtcgag cagtccgctg ccggcggcga
    13021 cgagcccgtg gcgtacgcgg gggttgtcgg ccatggcgcg caaccgggcg cgggtgcggg
    13081 cggggtcgcg gtcggcgagc gtctcccgcc agacctcgac cggcagggca ggcgcccgca
    13141 ggagagggaa gtcgagggct tcgtaccgcg gcatggggcg agtcaggtcc ttgtcgattg
    13201 cgtcgattgc gtcgattgct ttcatcggag aaagagcacc cgccaccaac tgggcctccg
    13261 gccggtggct acggcgcgga gggtgaggga gacaccggcc gcgccggtga ggagcccggg
    13321 attgtcgacg acgtgcccgg tggtctcgcg gtcgcggtac accagggccc gctcgggctc
    13381 ggcggcattg agcagctccg ccacgagtcg ggcgagtcca cgcgcggcgc cctcgctgcc
    13441 ccgcgcggcg aactcgtggg cgagcgcgac gcatccggcg aggccgtggc acacggtggg
    13501 cgagcgcggc acgtccccgg cggcgacccg gtcgagcagt ccgtccagcg cggcgaacgc
    13561 ccgtgcttcc agggcccggt cgccggtcgc gtcggcgacg gtgagcagcc cggcggccac
    13621 tcccccggtc ccgtggcacc aggcgggcac ggcttcgtcc ccgtcgtcgg ggtgcggggc
    13681 cacggggacg gaccgcggcc actggagctg ccggcctccg cggctgccga cctccagcag
    13741 ccatgccacc agccggtcga ggacgaggcg ttgcccgggc agccggtgac cgtgccgcca
    13801 ggcggtggcc agggcggcgg cgatacccgc tgctccgtgg gacatcccgg tgtcgagccg
    13861 tccctcgacg gcccaccgct gatcggcacc gacccacaac aggtaccgca ggcaccgctg
    13921 aagcgcctgc tcgacgagcg gggtcgcggg gcggacgtgg cacaggtggg cgaggacgcc
    13981 cgcgcacccg tagacgaggt cgtagtggtg agcggcgacg gcaccgggcc ggcggggcag
    14041 ctccatggcc aggacctgcc gggacagctg ttcgtccagt gcggcgaggc tgggcagaaa
    14101 acggggctcg tcggccgcga cctcgcgcag cgcgaaggcg aggccggccg tgccgtcgaa
    14161 gagccccgga tgcgtgaggg catcctcttg tgtggcggcg aaggcagcgc gcacgaagga
    14221 gaaggcccgg tcgcgcgacc gctccccttc cgcatcgcgc tccgcggtac gcgctgcgtg
    14281 gaggtggagg agcgccagcc cggcatgccc ctcgctgagg gaagcgccgt tccagaagga
    14341 cacctcgctc tgcccggcgg cgcgggcggc gtgcgcatcg gcgccggcgg ggctgtcgag
    14401 tcgttcccgg atcacgctcg cgacggcgtt cgcgcgggcg gcaagtccgg tcggcagaag
    14461 ggggctgggg tgcatgtgtg gggctctaca ggctcttcgg agggggtcct ccgtttcctt
    14521 tcggaggacc ccaccgtggt gatcggactc gatcggcagc gcggtcagca cttgccgttc
    14581 gtgcggacgg cggcgcaagc ggccgtcatc ttgatcgtct gccggatggt ctgcttgacg
    14641 gcccacttgc tggcgacgcg cgaggcgacg ctggcaaccg gggacagcga cgtctgagcc
    14701 gggtcggcgg aaacgatcac gcgagcgtca aggtcgaact cgtccatgaa tttacagcac
    14761 ctttcattcc gtaaaaccaa ccgcccgccg aggaaacgag gaagggattc caaaggagtt
    14821 cccgaggcgg tcagagaatg aatgtaatga ggccgaggac gctcttgaac ccgccgacct
    14881 tcctattctt cccccaccat gtggcgggac ggtccgccca gctgtccggt gcccgaccgt
    14941 cagcgcccct gcagggcgtc cagcccaact gccatgcaga gcgcgagtgt ccggtccaac
    15001 cccggatcct ggatacggat gacgtaccgg tcccggatcc cccacttccg ctcgaccgcc
    15061 agtacgggcc gcccgtcccg gacgaagtcg aagtggtaga cgaacggcac gggcggcaaa
    15121 gtgacgagcg gcacgacgag atcgacgacg tcccacatgc gtcgcgcaag cgccacaccg
    15181 acccgccgct ccttgcccac ggcggcgccc ttctccccct gcgtcagatg ccaagtggac
    15241 cgcagaaaag acgccttgaa gtccttgcga aagctgccga cgagatcccc accgggccct
    15301 gtcacgtcgt atgtggcccc gaggtcgatc acctcccgcg ccttgaatcc gccgatttcc
    15361 cgggaacggc cctcatcggt ccacaaggtc agctgctcct gcaacgcgaa ccgcttctgc
    15421 tccgcgaagg cgatgacctc accactttcc ggaagcgtga acacgtaccg gttcacgagt
    15481 ggggcgatct tctgcgtcat gagaatgtcg tcgggctgcc acatgcagga accgtaagca
    15541 tcggcagaac gcacactcgt gcatctcaag gcggagcaga cccccgccga ccggagggtg
    15601 gcgaagggcc gagtggccac ctccctctcc tgaattcccg cgtgaatccc ccagccactg
    15661 accgacccgc cgactcccga gggcatcgcc gagcctgagg gagccggtgg cgctcaactg
    15721 cccttccggt ccgacctggt gtcgtcgtgg acgagcgagg ggtagtcgtc gagggagatg
    15781 tcggcggaga tatcgtggcc ctcctggagc atggccgtga gggcggccgg gtcgttgagc
    15841 gcggagttgc gggccgctat cgcctcctgg gtgaggggcg ccaggaacgc gcccgttccg
    15901 cggccgcctt cctgacagcg cgagacatac ggccgcagct tctgctcgta ccgggcgaag
    15961 gctcggcggt ggtcgccggc cgcgagggcc agttcgccgg cgaggacata ggcgccgacg
    16021 atcgccgagc ccgtgcccat cccgccgacg gtggcgccat aggcggcatc gccaaggagc
    16081 gctatccgcc ccctcgacca cgtcggtacg tcgacgcggc ttatcgcgtc gaaatagagg
    16141 tcgtcggcat cccggacggt cccgacgagt tccgtggtgc gccagcccgc gccctcgtac
    16201 gcctggacga gggcctcgcg ctgggcctgt gggtcgcggc ggtcgtggcc cagtcgctcg
    16261 gaggcgaaga cgcagaatgc ctcgcccccg taggaggggt cgtcggcgcg gcggggcacg
    16321 cggccgaccg tcaccagtcg gccgggctcg ttgtaaccga cggcgtgggc ggcaaggtcc
    16381 ggcgccgcgc cgtgcgggag atcccagccg gcgacgtagt agccgaggtg gctgacgaag
    16441 tccgcttcgg ggccgaaggc gagccggcgc accgtggagt gcaggccgtc ggccccgata
    16501 accaggtcga aggtgcgggg cggggcgtgc tcgaaggtga catggacgcc gtcggcggtt
    16561 tcggtgagag aggtgaggga gtcgccgaag aggtatgcgg tggtgccggc gacggcggca
    16621 ggggcggcgg tgtcgtcgtg aggggtggga gtggggcaac tgtggtcgta gaggatgcgg
    16681 gagagttccg agcggaggat ctccacgtcg ccgccggcga actcgggcgg gagggccgcc
    16741 acatgattcc cccgggcatc gatgaaggtc agggaactac caccggtgcg gcgccgtctg
    16801 atctcctcca ggacgcccat cttctgcagt gccgccaggt gcgccgcacc gcggaagtcg
    16861 accgcgaagc cgcctccgcg gagggccggc gccgactcga ccacggtggg gcggtagcca
    16921 tagcgggcga gccaatgggc gagggccggg ccggcgatgc tggcgccgga gatgaggacc
    16981 gttcgggccc gcgcggcgga ggtcggcgtc ggttcgcgcc tctcgcgcgc cccgtacgcc
    17041 ccctgcgtct caagtgcctt gtccgtgtgg tgcggtgtcg ttgtgcgcgt catcggacgc
    17101 tccccctgtg tctgcgtggt gtggcgacac aacaactgta tccaccggac acagatctgt
    17161 atacccccgg acacagtttt aggatgcgga ggtggctgga gacgagaaga gcagtgcgtt
    17221 cggggatcag gcgggcagcg tcgagctgct gtggggcggg cgcgaacggc cgagccgggg
    17281 ccccaagccg gcgctgagcc tggagcggat cacgcggacg gccatcggcc tcgccgacac
    17341 cggcgggctc ggcgcggtct ccatgcaacg ggtcgcggcg gagctggact tcacgaagat
    17401 gtccctgtac cggtacgtgc ccggcaaggc ggagctggtc gccctgatga tcgacacggc
    17461 gatgggtgaa ccgccggagc cggcgggcgc cgcggccggc gactggcggg gcgcgctgcg
    17521 ggactgggca cagcggctcg cggcggtctt cgctcagcac ccatggctgc tgagcgctct
    17581 cgtcggaccg cgggtcatgg gccccaacga actcggctgg acggagcgcg cactggcggc
    17641 gctcgcgggc accgggctga ccggcggcga gcagctggat gccgtgctgg tggtgagcgg
    17701 gcacgtccgg gccatcgcgc aggtgtcggc gtcgatgggg gtgggcggcg cccccgcgaa
    17761 ggagccggag gcggcactga gcgccgcgct gaacgagctg ctcgtcgggc ggtccgagcg
    17821 gttccccgcg ctgagcgccg cgctggcggg caccgccggg ggcgaatccc gggaacaggc
    17881 ttgggagttc gggctggagc ggatcctgga cgggctggag gcgtacgcag gacgggggtg
    17941 agaagcccgc tcgcctacgt acgccccgcg ggaccctcgt cgtcgtgcta cacgcggggc
    18001 cctcgtcgtc gtgctacatc cccagtcgca cgttcttccg cggctgttcc ttggcgccgg
    18061 tcaggaggcc gtggagggtg gcgaattcgt cgacgcactt ggcggtgccg ttgaccacgc
    18121 agtccagggg ggcgtcggcg accacgaccg ggacgcccat ctcctcgcgg aggcggcggt
    18181 ccagcccccg gagcagggcg ccgccgccgg tgagggcgat gccgcgctcg atgatgtcgc
    18241 cggagagctc cggcgggcag tcgtccaggg tgttgtggac agcgcggacg atggcctcga
    18301 cgggttcggc gagggcggcg cggatctctt cggcggtgat ctcctggagc cgcgggaggc
    18361 cgctgaggtg gtcccgcccg cggacggtgt aggagtgggg ggaggggcgc gccgccctgt
    18421 ccgcgagcga ctcggcgtcg gtctcggcgt cggacgcggg gtcggatacg gagtcggacg
    18481 cggcgcccac ggtcaggcgg gtggggagcg ggcggtcgtc gtccggggtc cagaccgccg
    18541 agccgatggc gatcttgatg tcctcggcgg tgcgctcgcc gatggccagg ccgtgctcct
    18601 tcttgatgta cgtggagatg gcggcgtcca tcgcgtcgcc ggcgacccgc acggactggg
    18661 cggtgaccag gccgcccatg gagaccacgg cgacctcggt ggtgccgccg ccgatgtcga
    18721 cgaccatgca gccgaccggt tcggcgaccg ggaggcccgc gccgatcgcg gcggccatcg
    18781 gctcctcgat caggtgcacc tcgcgggcgc cggcgccccg tgcggagtcg atgacggcgc
    18841 gccgttcgac cccggtgatg ccagagggga cgcagatgac gacccggggg cgggagaagc
    18901 ggcggctggg cagggccttc ttcatcaggg cgcgcagcat ctgctcggcc gcgtcgaagt
    18961 cggcgatgac gccctcccgg agggggcgca tcgcggtgat cccggagggc gtgcggccga
    19021 tggtgcgttt ggcctccgaa ccgacggcga cgacgtcgcc ggcggcgttg acggcgacca
    19081 cggagggctc gttcagcacc acgcctttac cgcgcgcgta gacgagggtg ttggcggtgc
    19141 cgaggtcgat gcctatgtcg tacgtaccgg acgaagtgct ggacgccatg gggagttcgc
    19201 ttgctctctc tcgggaggac attgcgccgc agagagcgtc attgacgtgc caatgacgct
    19261 aattgcgggc aattatctag actactgggg gtgcggaatg gttcctgcgg gggcggatgc
    19321 gcccgggtgc agaagcagtc gggggcgggt cgtcaggggt cggggggcag tgcctcggcc
    19381 aggtcgtcga gggcgtccag gagcagctcg gtggcgcgga cggcgacgcc ctcgtgctcg
    19441 ccctcggcgc tccaccgctc ccaggcggcg tgcggctcgc cccagtccat cgcctcgccg
    19501 tcgcggacgg cccgggcggc gcggtccagg gcggggcgga gggcggcggc gaacgcggcg
    19561 gcgccgggcg agggccgggc gtcccggtcg ggcgggtgcg cctccaggat catcgtgacc
    19621 cggcccatgg tggcgagcgc ggcgctggcg gcgtgcgccc cgccgagcgg gaggccgcgg
    19681 tgccggaccg gctccttctc ggcacgggcc tcggtcgcct cccaggcggc gcgggccgca
    19741 cgggcgtcca gcagggcgtc gcggacctgc cggggccggc gctcggcggg ccgggcgtag
    19801 ccgtcgacga cggcgagcgc gtaacggccg ttggtggtca gccagtcggc gaggcggtcg
    19861 cggagccggg gcgtctccca ggcggggaac agcgcgtagg acagcatcgc gaggaccccg
    19921 ccgacgaggg tgagcacgag gcgttcctgg acggtctgtt cccagccggc gccgacgatg
    19981 ccgagcagga agacgacata ggccgcgatg caggccgagg tgacggagaa gccggtgcgc
    20041 atcagcaggt acatcaggaa gacgcagagc agggcgaggg cggcgctgac gtaggcgccg
    20101 gggtgggcca gcgccatcag ggcgccggcc agggtcacgc cgacgacggt gccggcgaag
    20161 cgggcgacgc cgcgggagta ggtctgggcg aagtcggggc gcatcaccat gacggaggcg
    20221 agcggggccc agtagccgtg gccgaagtgg agggcggcgc cgagcaggta gccggcgacg
    20281 gcgaccgcgg cgacgcggag cgcgtgccgc aggacgtgcg aggaccagcg ggcctcgcgg
    20341 cgcagggcgc gcagggcgac cgggacgagc cgggggacgc tggggcgcag caggtggccg
    20401 cgttcggctt cggtggtggg gcgggtggcc tcgacgggct cgtcggtgag ttcgacggcg
    20461 tcggcgagga gggagatcag gcggtaggcg gtgcgccggg cgggcccgcg gagcatcggg
    20521 ccgctggccg gtacttcgag ggcggccacc gcctccggtg gcagccggac cgggctggcg
    20581 tgccgtacgg cgtgcgcgac ggcgtccagg acggtggcgg cggcgcccag gagttcacgg
    20641 gcgcggtcgc gttcgggccc ctccaggggg gcgccgacga ccgggtcggc cagtgaggcg
    20701 aggaccgggc ggacgcgctc ggcgaggccg cgtgggccgt gcagctgtac ggggcggcgg
    20761 cgggcctggc ggggtgtcac ggtggcggcg gctcgggcgt ccatcagggg cgcggggtcg
    20821 aacggggcga ccgggtcgtg ccgcagccgg cgggcgtagt cggcctcggc ggccagcgcg
    20881 tcggcgaggg tgtcgcgctg gatgccccag gggcgcaccg ggaagaggac gatgagggcg
    20941 gcctggacga ggccgccgca ggcgatcagc gcggcgtgtt cgagggcgcc caggaccgac
    21001 gtcgggaggg tgacggtgat cagcatgatc gccacggtct gggtgccgac gaggccggag
    21061 accggcccga tcgcccaggc catgcccgcc aggagggtcc agccggtgag cagcaggacg
    21121 aaccagacga cgtgggcggc ggccaggtag ccgaggaagg tggagatcgc cagcgcgccg
    21181 gcgacggcca gcgccagcac cgggcggggc cgcatgctgc gctggaaggt gacgatgccg
    21241 gcggagaagg caccaaaggc ggaggagacc gcgagggcgg ggttgccgcg ccacaggcac
    21301 aggccgagga cgatggccac gccgaccgtg ccgcggatcg cgatcagcgg ggtgagcttg
    21361 gcgcgttcga tggtcagccc ggagcgggtg gcttccttca gcgcacgcga ccaggtcata
    21421 gcgagagaat acgggccggg agcaggggcg gccgggcgcc gggctggggg tgcccccggc
    21481 ggtagctggg ggacggtgcg caagggcgac ccggatgcct tcgcggcggg ttccccaggg
    21541 gccgctgcgg accctcgcag gggcgtgcgg ccgggcgccg gaggcggcgg acggcgccgg
    21601 ggcgcggacg tacgcccggt gtgccggaag ggggcgcgcg gaggtccatt ggccgcctgc
    21661 gttgcgcctc caccaggaaa atcacggtaa accggatctc cgttgcgcgt aaacaccaca
    21721 ggtcagagca ggtaagcgag tttcggttcc cgagggtgcg agcaagcaga caccccggga
    21781 gggaaacctg tccctgcccc gccccctctt gttggccggt cgggacaact cccggcccgt
    21841 tcgccaagga gaaggtcccg tgcgcaaatc ccttttcaaa ccggtgatcg ccttgatcgc
    21901 cctgaccgta ctcggcacca cggccggctg tgggacgagc gacgactccc agggcgcgcc
    21961 cgtacggttc agcggtccgc ggtcgggtgc cgccatgcag accgcgccgg ccgacaagaa
    22021 ctcgctggtg cagatgccca cccatccgat caacttccag gagaccagca aggtcggcgg
    22081 ggccggtggg aacaccccga tagccgtgac cacctaccac gggaagaagt ccggcttcac
    22141 ggggaaggtg tgggtctggg cgccgccgga gtactacgag aagaagaacg cgaacaaggg
    22201 cttcccggtc atggaggcgc tgcccggcgc ctacggctac ccggtcaatt actggatcgg
    22261 ctccgacctc aagctggagg agagcctcgc cacctggtcg aaggccggca agagcctgcc
    22321 gttcatcgtg gtgatgccgg tgctcaaccc caacgacaag cagtactacg acggcagtga
    22381 catcccgggc cagccgaaga tcggcacctg gctgagcaag gacgtccccg atctcgtccg
    22441 ggagaacttc cgcaccctga agacccgcaa cgcctggtgc atcatgggct cctcgtcggg
    22501 cggcttctcg gcgctgaaga acgtgctgca gaacccgaat gacttcaagg tggcaatccc
    22561 caacgggccg gacatcgtcc cggactcgcc gctgtggcga ggccacctca aggagatgcg
    22621 cgagaacaac cccgaggtgc tggcacgcca gctgaacgcc cacggcggac ccgacgtcta
    22681 tctggccttc caggacggct ccaaggagta caccgtgctg ccgaaggtgc ggaagttcct
    22741 cgcgcagtac gggcacgggc acgtgaagac gcggctgcag atcgtgccga acggcacgca
    22801 cagcggccag acctacgtca cgggtctggg catgggcacg atgcagtggg tcagcgccca
    22861 catgcagggg ccgaccggct gaggacgggc cgaccggcgg gcggtcgcgg cggacgcttc
    22921 ggtccgcggc gaccgccctc gtcgtatgtc gactgcgggc ggttcactgc ccgcagtcga
    22981 cgtcctggag catgatcggg tgcgactcca ggcggacgta ggcggtgaag ctgcgggtgg
    23041 cgccgccgtc ccagccggtg gtgacggtgg cccaaccgac gcccgcggac tgggcggtgg
    23101 tgaccgtgcc gacggtgatc gcccgcgggg tgttctgggc gcagagcagc aggtcgtagc
    23161 cgtcggtgtg ggccgcacgg tccttgaggt agtcggagac ctggtgcgcg cgctggtgcg
    23221 gggtggggcc gtgctggccg tagaagccgg tcaggaagcg gtggatctcg gcggcggtgt
    23281 ggcgaccggc ggggtcgctg cggacggtgg cggcagcggg tgcggtggcg gcgagggtca
    23341 ggccgagggc cgcggcacag gcggcgacgg cggtgacggg acgcgatgcg gtacgggaca
    23401 tggcaggtcc tcaccttcag ggcgtgtgac tgcgtagaca cccatgtccg gcgcatggtt
    23461 gcggtgccgg acaacccgaa caaaggggga cgggtgtccg catccggccg cgccgcccgc
    23521 cggccctgcg gcccctgtcc ccgcccccgt caggacacca cgtccttgcg ggcgaagccg
    23581 cggaaggcca gtgcgacgag caccagcgcg taggacaccg acaccgaggc accctggagc
    23641 atcccggacc attccagctg gggttggagg gcgtccgccc aggcgtactg ccagtgcgcg
    23701 ggcagcaccg cgcgccagtc gccgagcgcg gtgacctggt cgaggacgtt gccgacgatg
    23761 gtcagtccga cggcgccgcc gaccgcgccc agcggcgcgt cggtcaccgt ggacagccag
    23821 aacgccagcg ccgcggtgac cagttggctg acgaagacat agccggtcac cagcgccagc
    23881 cgcagcaccg cgtcgcccgg ggcgagcgcg cccccggtcg gcagttgcag cgggccccag
    23941 ccgtacgcgg cggtgcccac cgccagcgcg accagcggca gcagcagcat cgcggcggcg
    24001 ctgaacacca gccccacggt cagcttgctc agcagcagcc gggcccgcgg caccggcgcg
    24061 gccaacagat agcgcagcga cgcccagctg gcctccgagg ccacggtgtc cccgcagaac
    24121 agcgcgaccg gcaccaccag caggaagccg gcggagacga acagcgcggt ggcggcgaag
    24181 ttggcgccgg aagcggtggc ggtggtcatc agactgatcc ggccggagtt ccgggtgctg
    24241 ggatcgccgc cgatcgcgaa cgccgcgacc aggacgaacg gcagcagcgt caggatcgcg
    24301 ccgatcacca gggtgcggcg gcggcgcagc tggcggcggg cctcgacgcg cagcggcagg
    24361 gtgcggcggg cgcggtagcc gggcgccgcc gccggggtgg tcgcggtcat cgtccgtctc
    24421 ctccgatcag ggtgaggaag gcgtcctcca ggcggcggtg cgggccgacg cggtg
//
