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Overview
1.1
1.2
5.1
12.1
23.1
30.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_PNGD01000001.1 (Streptococcus sp. UMB0029)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii,azole-containing-RiPP | 18,778 | 67,149 |  |
Region 1.2 | terpene-precursor | 118,839 | 139,714 |

NZ_PNGD01000013.1 (Streptococcus sp. UMB0029)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 5.1 | RiPP-like | 51,744 | 62,040 |

NZ_PNGD01000002.1 (Streptococcus sp. UMB0029)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 12.1 | furan,RaS-RiPP | 272 | 37,768 |

NZ_PNGD01000003.1 (Streptococcus sp. UMB0029)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 23.1 | T3PKS | 103,266 | 144,438 |

NZ_PNGD01000009.1 (Streptococcus sp. UMB0029)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 30.1 | RiPP-like | 67,002 | 79,155 |

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-ii,azole-containing-RiPP | 18,778 | 67,149 |  |
Region 1.2 | terpene-precursor | 118,839 | 139,714 |
Region 5.1 | RiPP-like | 51,744 | 62,040 |
Region 12.1 | furan,RaS-RiPP | 272 | 37,768 |
Region 23.1 | T3PKS | 103,266 | 144,438 |
Region 30.1 | RiPP-like | 67,002 | 79,155 |

No secondary metabolite regions were found in these records:
  NZ_PNGD01000010.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000011.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000012.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000014.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000015.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000016.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000017.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000018.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000019.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000020.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000021.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000022.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000023.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000024.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000025.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000026.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000027.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000028.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000029.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000030.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000004.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000005.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000006.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000007.1 (Streptococcus sp. UMB0029)
  NZ_PNGD01000008.1 (Streptococcus sp. UMB0029)

Compact view
NZ_PNGD01000001.1 - Region 1 - azole-containing-RiPP,lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 18,778 - 67,149 nt. (total: 48,372 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Azole RiPPs
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: hydrolase
CJ239_RS00265: amidohydrolase

smcogs
  SMCOG1244: amidohydrolase

Lyases: cyclase
CJ239_RS00160: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

CJ239_RS00175: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | azole-containing-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001391.3 |  |  | 0.31 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000521.3 |  |  | 0.31 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0001210.5 |  |  | 0.30 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001311.5 |  |  | 0.30 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0002663.2 |  |  | 0.29 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639
BGC0000626.3 |  |  | 0.28 | ribosomal | thuricin | Bacillus thuringiensis
BGC0001209.3 |  |  | 0.28 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0000539.5 |  |  | 0.27 | ribosomal | nukacin ISK-1 | Staphylococcus warneri
BGC0000542.3 |  |  | 0.27 | ribosomal | paenicidin B | Paenibacillus terrae
BGC0000541.5 |  |  | 0.27 | ribosomal | paenicidin A | Paenibacillus polymyxa

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002110.3 |  | 0.57 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0000517.4 |  | 0.56 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000623.3 |  | 0.54 | ribosomal | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000525.5 |  | 0.54 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000521.3 |  | 0.53 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0002663.2 |  | 0.53 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639
BGC0001391.3 |  | 0.53 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0001229.4 |  | 0.53 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001311.5 |  | 0.52 | ribosomal | flavecins | Ruminococcus flavefaciens FD-1
BGC0000555.3 |  | 0.52 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for CJ239_RS00160

CJ239_RS00165
Leader:
MNNKFTGKINELELEQLVGDNQVVGG
Core:
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
Core with dehydrations:
I Dhb P Dhb I I A A Dhb I Dha F A G V Dhb F Dhb V Dhb L N A G A Cys P Dhb Dha G Cys Dhb K Dha Cys N K

#### antiSMASH-DB 4.0 matches for CJ239_RS00165

100.0%
NZ_PNGD01000001.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide
Lanthipeptides: CJ239_RS00165_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
94.6%
NZ_CKMQ01000043.1 and 8 others:
NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS09950_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptide NZ_LR216041.1 Lanthipeptides: E0F00_RS05470_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide
Lanthipeptides: AE832_RS09950_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
I T P T I I A T I S F G V T F T V T L N A G A C P T S G C T K S C N K
1
I T P T I I P A T I S F V G V T F T V T L N A G A C P T S G C T K S C N K
37
63.2%
NZ_CP017953.1 and 15 others:
NZ_CP017953.1 Lanthipeptides: BAMY_RS16390_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide
Lanthipeptides: BAMY_RS16390_lanthipeptide
2
T P T I I-A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
T P T++ A T I G T F T V T L+A +C P T S C T K C N K
2
T P T V V L T A T I G L T G T T F T V T L S A A S C P T S A C T K Q C N K
38
with 85 more sequence matches
Only the first 10 are displayed here.
53.8%
NZ_CP033054.1 and 11 others:
NZ_CP033054.1 Lanthipeptides: D9777_RS18840_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide
Lanthipeptides: D9777_RS18840_lanthipeptide
5
I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
++ A T I G T F T V T L+A +C P T S C T K C N K
7
V L T A T I G L T G T T F T V T L S A A S C P T S A C T K Q C N K
39
48.6%
NZ_JALAUA010000003.1 and 1 other:
NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptide
Lanthipeptides: MOD32_RS04870_lanthipeptide
5
I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
+ A + G T F T V T L+A +C P T S C T C N K
4
V T A I L T A L T G T T F T V T L S A A S C P T S A C T N L C N K
36
46.2%
NZ_WHOM01000078.1 and 1 other:
NZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29290_lanthipeptide
Lanthipeptides: GCN81_RS29290_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
I T P T I+ A T G + + G C P T S G C T K C
8
I T P T I L P A T G V I V G A S A A L Q---G G C P T S G C T K R C
39
45.9%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
11
S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
+ G T F T V T L+A +C P T S C T C N K
10
A L T G T T F T V T L S A A S C P T S A C T N L C N K
36
43.2%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
T P I+ A + V T C P T S C+K S C N K
7
T P A I V T A I S A V T A V T A Q-----S P C P T S A C S K S C N K
37
40.5%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I I A T I+ + A C P T+ C T C
11
T P T I I G A T I A---------V T A S L C P T T K C T S R C
35
40.5%
NZ_CP015591.1 and 15 others:
NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide
Lanthipeptides: A7A70_RS27550_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I+ A T I+ T V++ C P T+ C T C
11
T P T I V E A T I A A-----T V S I----C P T T K C T S R C
35
40.5%
NZ_JABBGE010000004.1 and 1 other:
NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13570_lanthipeptide
Lanthipeptides: HHL19_RS13570_lanthipeptide
9
T I S F A G V T F T V T L-N A G A C P T S G C T K S C
35
T S A V T T L +A A C P T+ C T C
2
T W S C A V V T A V A T L V S A S A C P T T K C T S Q C
29
40.5%
NZ_BMRY01000003.1 and 19 others:
NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12360_lanthipeptide NZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptide NZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptide NZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptide NZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptide NZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptide NZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptide NZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptide NZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptide NZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptide NZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptide NZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptide NZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptide NZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptide NZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptide NZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptide NZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptide NZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide NZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide
Lanthipeptides: IE140_RS12360_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I I A T + G C P T S G C T K C
9
T P T I I P A T A V T T V I V G A S A A M Q G G C P T S G C T K R C
42
40.5%
NZ_BMSZ01000006.1 and 4 others:
NZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12790_lanthipeptide NZ_CP021707.1 Lanthipeptides: CCZ36_RS18195_lanthipeptide NZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide NZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide
Lanthipeptides: IE135_RS12790_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
I T P T I+ A T + G C P T S G C T K C
8
I T P T I V P A T A V T T V I V G A S A A M Q G G C P T S G C T K R C
42

#### MIBiG 4.0 matches for CJ239_RS00165

21.6%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
V T L N A G A C P T S G C T K S C
35
V ++A C P T+ C T C
21
V G V S A A F C P T T K C T S R C
37
16.2%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
26
C P T S G C T K S C
35
C P T+ C T C
17
C P T T K C T S K C
26
CJ239_RS00170
Leader:
MAQKDFHQKINSQLLEEISDNSAVGA
Core:
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
Core with dehydrations:
G W A Q L Dha F I Dha E A L G N K G A V Cys Dhb G Dhb I E Cys Q N N Cys R

#### antiSMASH-DB 4.0 matches for CJ239_RS00170

100.0%
NZ_CKMQ01000043.1 and 10 others:
NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS11585_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptide NZ_LR216041.1 Lanthipeptides: E0F00_RS05465_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptide NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide
Lanthipeptides: AE832_RS11585_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
60.0%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide
Lanthipeptides: EL241_RS01725_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
G W L S ++L G N K G V C T T E C Q C R
2
G W K D L S---K S L G N K G Y V C T L T K E C Q K L C R
28
53.3%
NZ_CP063276.1 and 1 other:
NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide
Lanthipeptides: IM743_RS02795_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
+S L G N K G A C T T+E C Q N N C
6
V S C R L G N K G A W C T L T V E C Q N N C
27
with 100 more sequence matches
Only the first 10 are displayed here.
53.3%
NZ_FOBE01000018.1:
Lanthipeptides: BMW61_RS13085_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C
29
G W S +S A L G N+G+ C T T E C Q C
1
G W--Y S E M S A A L G N R G S Y C T L T K E C Q A C C
27
50.0%
NZ_CP006058.1 and 23 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide
Lanthipeptides: BAMY6639_RS13800_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N K G A C T T+E C Q++C
6
I S C K L G N K G A W C T L T V E C Q S S C
27
50.0%
NZ_CP061033.1 and 1 other:
NZ_CP061033.1 Lanthipeptides: IAU67_RS09320_lanthipeptide
Lanthipeptides: IAU67_RS09320_lanthipeptide
9
S E A L G N K G A V C T G T I E C Q N N C R
30
S A L G N+G C T G T I E C Q C+
1
S W A L G N E G N F C T G T I E C Q K T C Q
22
46.7%
NC_021362.1 and 29 others:
NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide
Lanthipeptides: BALI_RS00925_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
I S L G N K G C T T E C Q +C+
6
I S C Q L G N K G Q W C T L T K E C Q R S C K
28
46.7%
NZ_BJTV01000004.1 and 1 other:
NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide
Lanthipeptides: TNCT1_RS10200_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S+A L G N G C T T E C Q N C
8
L S D A L G N H G G W C T L T K E C Q A N C N
30
46.7%
NZ_BNBV01000031.1 and 1 other:
NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide
Lanthipeptides: IE286_RS22995_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S+A L G N G C T T E C Q N C
8
L S D A L G N S G G W C T L T K E C Q P N C N
30
46.7%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
+S+A L G N G C T T E C Q N C
8
L S D A L G N H G G W C T L T K E C Q P N C
29
46.7%
NZ_CP034118.1 and 1 other:
NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide
Lanthipeptides: EG886_RS06305_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N G C T T E C Q N C
6
I S C H L G N T G R F C T L T K E C Q P N C
27
46.7%
NZ_KE384107.1:
Lanthipeptides: G586_RS23925_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C
29
G W + +S +L G N+G+ C T T E C Q C
1
G W--Y A D L S A S L G N R G S Y C T I T K E C Q A C C
27
44.7%
NZ_CM000756.1 and 7 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide
Lanthipeptides: BTHUR0011_RS34475_lanthipeptide
7
F I S E A L G N K G A V C T G T I E C Q N N C R
30
I S E G N K G V C T T+E C N N C R
14
I I S E T F G N K G K V C T Y T V E C V N N C R
37

#### MIBiG 4.0 matches for CJ239_RS00170

46.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N K G A C T T+E C +C
6
I S C R L G N K G A Y C T L T V E C M P S C
27
46.7%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S A L G N G C T T E C Q N C
8
L S N A L G N N G G W C T L T K E C Q P N C N
30
18.9%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
11
A L G N K G A V C T G T I E C Q N N C
29
A+G A C T +C + C
20
A V G V S A A F C P-T T K C T S R C
37
with 1 more sequence matches
17.9%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T G T I E C Q N N C
29
C T + E C Q N C
28
C T L S K E C Q P N C
38
allorf_038888_039007
Leader:
MSVRFLKTSLAS
Core:
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
Core with dehydrations:
Cys Dha V F A Dha Dha D I V Dha Dhb I Dha Q K Dha Y R Q P Dhb K Dhb F Q F

#### antiSMASH-DB 4.0 matches for allorf_038888_039007

100.0%
NZ_NWMU01000024.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: allorf_038888_039007_lanthipeptide
Lanthipeptides: allorf_25415_25534_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
88.9%
NZ_VMMF01000004.1:
Lanthipeptides: allorf_19081_19194_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F
25
C S V F A S S D I V S T I S Q K S Y R Q P K T F
1
C S V F A S S D I V S T I S Q K S Y R Q P I K T F
25
81.5%
NZ_ALSD01000046.1 and 1 other:
NZ_LT545678.1 Lanthipeptides: allorf_1389515_1389652_lanthipeptide
Lanthipeptides: allorf_02432_02569_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C S V F A S S I V T I +K S Y R Q P T K F Q F
1
C S V F A S S G I V V T I P K K S Y R Q P T K N F Q F
27
with 2 more sequence matches
20.5%
NZ_FNPT01000004.1:
Lanthipeptides: allorf_355996_356196_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C++F S +V + S + R P T +F
14
C N L F K C S L M V V S H S C P A D R P P D T T L R F
40
16.7%
NZ_SPGD01000003.1:
Lanthipeptides: allorf_036291_036446_lanthipeptide
4
F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
F + +++ +S K Y + K+F F
8
F E V A G V I N E V S N K E Y S K V G K S F A F
31

#### MIBiG 4.0 matches for allorf_038888_039007

11.1%
BGC0002130.3 (QKI29070.1):
Lanthipeptide: cacaoidin
1
C S V F A S
6
C+++A S
5
C T I Y A S
10

#### Lanthipeptide(s) for CJ239_RS00175

CJ239_RS00165
Leader:
MNNKFTGKINELELEQLVGDNQVVGG
Core:
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
Core with dehydrations:
I Dhb P Dhb I I A A Dhb I Dha F A G V Dhb F Dhb V Dhb L N A G A Cys P Dhb Dha G Cys Dhb K Dha Cys N K

#### antiSMASH-DB 4.0 matches for CJ239_RS00165

100.0%
NZ_PNGD01000001.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00165_lanthipeptide
Lanthipeptides: CJ239_RS00165_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
94.6%
NZ_CKMQ01000043.1 and 8 others:
NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS09950_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS02065_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS01730_lanthipeptide NZ_LR216041.1 Lanthipeptides: E0F00_RS05470_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05985_lanthipeptide
Lanthipeptides: AE832_RS09950_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
I T P T I I A T I S F G V T F T V T L N A G A C P T S G C T K S C N K
1
I T P T I I P A T I S F V G V T F T V T L N A G A C P T S G C T K S C N K
37
63.2%
NZ_CP017953.1 and 15 others:
NZ_CP017953.1 Lanthipeptides: BAMY_RS16390_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptide NZ_CP021011.1 Lanthipeptides: B6257_RS06470_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptide NZ_CP041784.1 Lanthipeptides: FOV14_RS15890_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptide NZ_CP048002.1 Lanthipeptides: GWK37_RS05695_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptide NZ_CP097326.1 Lanthipeptides: M5J22_RS16180_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptide NZ_CP097784.1 Lanthipeptides: MF619_RS16150_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptide NZ_JAAKXX010000011.1 Lanthipeptides: G6H00_RS11805_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide NZ_LMAG01000012.1 Lanthipeptides: ASQ47_RS06815_lanthipeptide
Lanthipeptides: BAMY_RS16390_lanthipeptide
2
T P T I I-A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
T P T++ A T I G T F T V T L+A +C P T S C T K C N K
2
T P T V V L T A T I G L T G T T F T V T L S A A S C P T S A C T K Q C N K
38
with 85 more sequence matches
Only the first 10 are displayed here.
53.8%
NZ_CP033054.1 and 11 others:
NZ_CP033054.1 Lanthipeptides: D9777_RS18840_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptide NZ_CP047268.1 Lanthipeptides: GKS41_RS18605_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptide NZ_CP072563.1 Lanthipeptides: J6600_RS15935_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptide NZ_CP116014.1 Lanthipeptides: PF996_RS17885_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptide NZ_JAANHO010000006.1 Lanthipeptides: G9F75_RS12560_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide NZ_JAIONG010000001.1 Lanthipeptides: K8B35_RS01365_lanthipeptide
Lanthipeptides: D9777_RS18840_lanthipeptide
5
I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
++ A T I G T F T V T L+A +C P T S C T K C N K
7
V L T A T I G L T G T T F T V T L S A A S C P T S A C T K Q C N K
39
48.6%
NZ_JALAUA010000003.1 and 1 other:
NZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04870_lanthipeptide
Lanthipeptides: MOD32_RS04870_lanthipeptide
5
I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
+ A + G T F T V T L+A +C P T S C T C N K
4
V T A I L T A L T G T T F T V T L S A A S C P T S A C T N L C N K
36
46.2%
NZ_WHOM01000078.1 and 1 other:
NZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29290_lanthipeptide
Lanthipeptides: GCN81_RS29290_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
I T P T I+ A T G + + G C P T S G C T K C
8
I T P T I L P A T G V I V G A S A A L Q---G G C P T S G C T K R C
39
45.9%
NZ_CP047645.1 and 5 others:
NZ_CP047645.1 Lanthipeptides: GSN02_RS17435_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_NJRE01000008.1 Lanthipeptides: CE047_RS18550_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide NZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03735_lanthipeptide
Lanthipeptides: GSN02_RS17435_lanthipeptide
11
S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
+ G T F T V T L+A +C P T S C T C N K
10
A L T G T T F T V T L S A A S C P T S A C T N L C N K
36
43.2%
NZ_CM000756.1 and 17 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14765_lanthipeptide NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS14760_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29740_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29735_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS29730_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26900_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS26895_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22545_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS22540_lanthipeptide
Lanthipeptides: BTHUR0011_RS14765_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C N K
37
T P I+ A + V T C P T S C+K S C N K
7
T P A I V T A I S A V T A V T A Q-----S P C P T S A C S K S C N K
37
40.5%
NZ_CM000721.1 and 9 others:
NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptide NZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide
Lanthipeptides: BCERE0010_RS29355_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I I A T I+ + A C P T+ C T C
11
T P T I I G A T I A---------V T A S L C P T T K C T S R C
35
40.5%
NZ_CP015591.1 and 15 others:
NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptide NZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptide NZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide
Lanthipeptides: A7A70_RS27550_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I+ A T I+ T V++ C P T+ C T C
11
T P T I V E A T I A A-----T V S I----C P T T K C T S R C
35
40.5%
NZ_JABBGE010000004.1 and 1 other:
NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13570_lanthipeptide
Lanthipeptides: HHL19_RS13570_lanthipeptide
9
T I S F A G V T F T V T L-N A G A C P T S G C T K S C
35
T S A V T T L +A A C P T+ C T C
2
T W S C A V V T A V A T L V S A S A C P T T K C T S Q C
29
40.5%
NZ_BMRY01000003.1 and 19 others:
NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12360_lanthipeptide NZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptide NZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05295_lanthipeptide NZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptide NZ_CP079114.1 Lanthipeptides: KV381_RS19415_lanthipeptide NZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptide NZ_CP084357.1 Lanthipeptides: LEL86_RS34975_lanthipeptide NZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptide NZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11030_lanthipeptide NZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptide NZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32890_lanthipeptide NZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptide NZ_JNLT01000014.1 Lanthipeptides: CD02_RS0123035_lanthipeptide NZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptide NZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100135_lanthipeptide NZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptide NZ_KZ819178.1 Lanthipeptides: DBP20_RS18445_lanthipeptide NZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide NZ_NNBN01000001.1 Lanthipeptides: CG717_RS03745_lanthipeptide
Lanthipeptides: IE140_RS12360_lanthipeptide
2
T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
T P T I I A T + G C P T S G C T K C
9
T P T I I P A T A V T T V I V G A S A A M Q G G C P T S G C T K R C
42
40.5%
NZ_BMSZ01000006.1 and 4 others:
NZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12790_lanthipeptide NZ_CP021707.1 Lanthipeptides: CCZ36_RS18195_lanthipeptide NZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide NZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19730_lanthipeptide
Lanthipeptides: IE135_RS12790_lanthipeptide
1
I T P T I I A A T I S F A G V T F T V T L N A G A C P T S G C T K S C
35
I T P T I+ A T + G C P T S G C T K C
8
I T P T I V P A T A V T T V I V G A S A A M Q G G C P T S G C T K R C
42

#### MIBiG 4.0 matches for CJ239_RS00165

21.6%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
V T L N A G A C P T S G C T K S C
35
V ++A C P T+ C T C
21
V G V S A A F C P T T K C T S R C
37
16.2%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
26
C P T S G C T K S C
35
C P T+ C T C
17
C P T T K C T S K C
26
CJ239_RS00170
Leader:
MAQKDFHQKINSQLLEEISDNSAVGA
Core:
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
Core with dehydrations:
G W A Q L Dha F I Dha E A L G N K G A V Cys Dhb G Dhb I E Cys Q N N Cys R

#### antiSMASH-DB 4.0 matches for CJ239_RS00170

100.0%
NZ_CKMQ01000043.1 and 10 others:
NZ_CKMQ01000043.1 Lanthipeptides: AE832_RS11585_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptide NZ_CKMR01000002.1 Lanthipeptides: AD782_RS11690_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptide NZ_FIXU01000003.1 Lanthipeptides: A1M11_RS11670_lanthipeptide NZ_LR216041.1 Lanthipeptides: E0F00_RS05465_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptide NZ_LR216046.1 Lanthipeptides: E0E82_RS05980_lanthipeptide NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide NZ_PNGD01000001.1 Lanthipeptides: CJ239_RS00170_lanthipeptide
Lanthipeptides: AE832_RS11585_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
60.0%
NZ_LR134483.1 and 1 other:
NZ_LR134483.1 Lanthipeptides: EL241_RS01725_lanthipeptide
Lanthipeptides: EL241_RS01725_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C R
30
G W L S ++L G N K G V C T T E C Q C R
2
G W K D L S---K S L G N K G Y V C T L T K E C Q K L C R
28
53.3%
NZ_CP063276.1 and 1 other:
NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide
Lanthipeptides: IM743_RS02795_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
+S L G N K G A C T T+E C Q N N C
6
V S C R L G N K G A W C T L T V E C Q N N C
27
with 100 more sequence matches
Only the first 10 are displayed here.
53.3%
NZ_FOBE01000018.1:
Lanthipeptides: BMW61_RS13085_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C
29
G W S +S A L G N+G+ C T T E C Q C
1
G W--Y S E M S A A L G N R G S Y C T L T K E C Q A C C
27
50.0%
NZ_CP006058.1 and 23 others:
NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide NZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide
Lanthipeptides: BAMY6639_RS13800_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N K G A C T T+E C Q++C
6
I S C K L G N K G A W C T L T V E C Q S S C
27
50.0%
NZ_CP061033.1 and 1 other:
NZ_CP061033.1 Lanthipeptides: IAU67_RS09320_lanthipeptide
Lanthipeptides: IAU67_RS09320_lanthipeptide
9
S E A L G N K G A V C T G T I E C Q N N C R
30
S A L G N+G C T G T I E C Q C+
1
S W A L G N E G N F C T G T I E C Q K T C Q
22
46.7%
NC_021362.1 and 29 others:
NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptide NZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptide NZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptide NZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptide NZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptide NZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptide NZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptide NZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptide NZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptide NZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptide NZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptide NZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptide NZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptide NZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide NZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide
Lanthipeptides: BALI_RS00925_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
I S L G N K G C T T E C Q +C+
6
I S C Q L G N K G Q W C T L T K E C Q R S C K
28
46.7%
NZ_BJTV01000004.1 and 1 other:
NZ_BJTV01000004.1 Lanthipeptides: TNCT1_RS10200_lanthipeptide
Lanthipeptides: TNCT1_RS10200_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S+A L G N G C T T E C Q N C
8
L S D A L G N H G G W C T L T K E C Q A N C N
30
46.7%
NZ_BNBV01000031.1 and 1 other:
NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide
Lanthipeptides: IE286_RS22995_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S+A L G N G C T T E C Q N C
8
L S D A L G N S G G W C T L T K E C Q P N C N
30
46.7%
NZ_CP016795.1 and 5 others:
NZ_CP016795.1 Lanthipeptides: BC342_RS18360_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP036534.1 Lanthipeptides: EZV63_RS18960_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide NZ_CP094676.1 Lanthipeptides: L6J92_RS01495_lanthipeptide
Lanthipeptides: BC342_RS18360_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
+S+A L G N G C T T E C Q N C
8
L S D A L G N H G G W C T L T K E C Q P N C
29
46.7%
NZ_CP034118.1 and 1 other:
NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide
Lanthipeptides: EG886_RS06305_lanthipeptide
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N G C T T E C Q N C
6
I S C H L G N T G R F C T L T K E C Q P N C
27
46.7%
NZ_KE384107.1:
Lanthipeptides: G586_RS23925_lanthipeptide
1
G W A Q L S F I S E A L G N K G A V C T G T I E C Q N N C
29
G W + +S +L G N+G+ C T T E C Q C
1
G W--Y A D L S A S L G N R G S Y C T I T K E C Q A C C
27
44.7%
NZ_CM000756.1 and 7 others:
NZ_CM000756.1 Lanthipeptides: BTHUR0011_RS34475_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP031749.1 Lanthipeptides: DPQ26_RS30450_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_CP036071.1 Lanthipeptides: EXW41_RS29770_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide NZ_WBPC01000036.1 Lanthipeptides: F8159_RS30260_lanthipeptide
Lanthipeptides: BTHUR0011_RS34475_lanthipeptide
7
F I S E A L G N K G A V C T G T I E C Q N N C R
30
I S E G N K G V C T T+E C N N C R
14
I I S E T F G N K G K V C T Y T V E C V N N C R
37

#### MIBiG 4.0 matches for CJ239_RS00170

46.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
8
I S E A L G N K G A V C T G T I E C Q N N C
29
I S L G N K G A C T T+E C +C
6
I S C R L G N K G A Y C T L T V E C M P S C
27
46.7%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
8
I S E A L G N K G A V C T G T I E C Q N N C R
30
+S A L G N G C T T E C Q N C
8
L S N A L G N N G G W C T L T K E C Q P N C N
30
18.9%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
11
A L G N K G A V C T G T I E C Q N N C
29
A+G A C T +C + C
20
A V G V S A A F C P-T T K C T S R C
37
with 1 more sequence matches
17.9%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T G T I E C Q N N C
29
C T + E C Q N C
28
C T L S K E C Q P N C
38
allorf_038888_039007
Leader:
MSVRFLKTSLAS
Core:
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
Core with dehydrations:
Cys Dha V F A Dha Dha D I V Dha Dhb I Dha Q K Dha Y R Q P Dhb K Dhb F Q F

#### antiSMASH-DB 4.0 matches for allorf_038888_039007

100.0%
NZ_NWMU01000024.1 and 1 other:
NZ_PNGD01000001.1 Lanthipeptides: allorf_038888_039007_lanthipeptide
Lanthipeptides: allorf_25415_25534_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
88.9%
NZ_VMMF01000004.1:
Lanthipeptides: allorf_19081_19194_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F
25
C S V F A S S D I V S T I S Q K S Y R Q P K T F
1
C S V F A S S D I V S T I S Q K S Y R Q P I K T F
25
81.5%
NZ_ALSD01000046.1 and 1 other:
NZ_LT545678.1 Lanthipeptides: allorf_1389515_1389652_lanthipeptide
Lanthipeptides: allorf_02432_02569_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C S V F A S S I V T I +K S Y R Q P T K F Q F
1
C S V F A S S G I V V T I P K K S Y R Q P T K N F Q F
27
with 2 more sequence matches
20.5%
NZ_FNPT01000004.1:
Lanthipeptides: allorf_355996_356196_lanthipeptide
1
C S V F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
C++F S +V + S + R P T +F
14
C N L F K C S L M V V S H S C P A D R P P D T T L R F
40
16.7%
NZ_SPGD01000003.1:
Lanthipeptides: allorf_036291_036446_lanthipeptide
4
F A S S D I V S T I S Q K S Y R Q P T K T F Q F
27
F + +++ +S K Y + K+F F
8
F E V A G V I N E V S N K E Y S K V G K S F A F
31

#### MIBiG 4.0 matches for allorf_038888_039007

11.1%
BGC0002130.3 (QKI29070.1):
Lanthipeptide: cacaoidin
1
C S V F A S
6
C+++A S
5
C T I Y A S
10

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57
Confidence: strong
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.66 out of 29.38
Confidence: medium
ANR
Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.45 out of 26.33
Confidence: medium
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.03 out of 23.79
Confidence: medium
Additional weak hits (3):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.50 out of 30.22
Confidence: weak
NrdR
Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 19.31 out of 27.18
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.42 out of 29.25
Confidence: weak
(Thi)azol(in)e containing peptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
Lanthipeptides
TFBS Finder
Azole RiPPs
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

CJ239_RS00165 - Class II
  Cleavage pHMM score: -1.00
  RODEO score: 0
  Monoisotopic mass: 3460.8 Da
  Molecular weight: 3463.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3481.0 Da N = 1
    3499.0 Da N = 2
    3517.1 Da N = 3
    3535.1 Da N = 4
    3553.1 Da N = 5
    3571.1 Da N = 6
    3589.1 Da N = 7
    3607.2 Da N = 8
CJ239_RS00170 - Class II
  Cleavage pHMM score: -5.50
  RODEO score: 0
  Monoisotopic mass: 3097.5 Da
  Molecular weight: 3099.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3117.5 Da N = 1
allorf_038888_039007 - Class II
  Cleavage pHMM score: -3.50
  RODEO score: 0
  Monoisotopic mass: 2892.5 Da
  Molecular weight: 2894.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2912.2 Da N = 1
    2930.3 Da N = 2
    2948.3 Da N = 3
    2966.3 Da N = 4
    2984.3 Da N = 5
    3002.3 Da N = 6
    3020.4 Da N = 7
    3038.4 Da N = 8
CJ239_RS00165 - Class II
  Cleavage pHMM score: -1.00
  RODEO score: 0
  Monoisotopic mass: 3460.8 Da
  Molecular weight: 3463.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3481.0 Da N = 1
    3499.0 Da N = 2
    3517.1 Da N = 3
    3535.1 Da N = 4
    3553.1 Da N = 5
    3571.1 Da N = 6
    3589.1 Da N = 7
    3607.2 Da N = 8
CJ239_RS00170 - Class II
  Cleavage pHMM score: -5.50
  RODEO score: 0
  Monoisotopic mass: 3097.5 Da
  Molecular weight: 3099.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3117.5 Da N = 1
allorf_038888_039007 - Class II
  Cleavage pHMM score: -3.50
  RODEO score: 0
  Monoisotopic mass: 2892.5 Da
  Molecular weight: 2894.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2912.2 Da N = 1
    2930.3 Da N = 2
    2948.3 Da N = 3
    2966.3 Da N = 4
    2984.3 Da N = 5
    3002.3 Da N = 6
    3020.4 Da N = 7
    3038.4 Da N = 8

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ANR | Anaerobic transcriptional regulator
FuR variant 1 | Ferric Uptake Regulator
IolR | Regulator of the inositol catabolism
ToxT | Regulator of MSHA biosynthesis

Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_PNGD01000001.1 - Region 2 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 118,839 - 139,714 nt. (total: 20,876 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: sulfhydrylase
CJ239_RS00615: O-succinylhomoserine sulfhydrylase

smcogs
  SMCOG1168: O-succinylhomoserine sulfhydrylase

Hydrolases: back translocase
CJ239_RS00560: GTP-binding protein LepA

smcogs
  SMCOG1190: GTP-binding protein LepA

Ligases: synthetase
CJ239_RS00585: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001605.3 |  | 0.35 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000815.4 |  | 0.35 | other (other) | loline, N-acetylnorloline, N-formylloline | Epichloe uncinata
BGC0000633.3 |  | 0.34 | terpene | carotenoid | Streptomyces avermitilis
BGC0001227.3 |  | 0.34 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000648.3 |  | 0.34 | terpene | carotenoid | Myxococcus xanthus
BGC0001456.3 |  | 0.33 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001529.5 |  | 0.32 | other (other) | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0001605.3 |  | 0.35 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000815.4 |  | 0.35 | other (other) | loline, N-acetylnorloline, N-formylloline | Epichloe uncinata
BGC0000633.3 |  | 0.34 | terpene | carotenoid | Streptomyces avermitilis
BGC0001227.3 |  | 0.34 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000648.3 |  | 0.34 | terpene | carotenoid | Myxococcus xanthus
BGC0001456.3 |  | 0.33 | terpene | isorenieratene | Streptomyces argillaceus
BGC0001529.5 |  | 0.32 | other (other) | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
CJ239_RS00585: PT_FPPS_like
Domain 1 (27 - 273): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  IPP, DMAPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.47 out of 21.55
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57
Confidence: strong
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.55 out of 19.26
Confidence: medium
Additional weak hits (4):
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.74 out of 26.06
Confidence: weak
PerR
Description: Peroxide regulator
Species: Bacillus & Staphylococcus sp.
Score: 23.28 out of 28.14
Confidence: weak
BldD
Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 18.67 out of 23.43
Confidence: weak
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.13 out of 25.88
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ArcA | Repressor of carbon oxidation
CRP | Cyclic AMP receptor protein
ToxT | Regulator of MSHA biosynthesis

NZ_PNGD01000013.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 51,744 - 62,040 nt. (total: 10,297 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: reductase
CJ239_RS09380: alkyl hydroperoxide reductase/ Thiol specific

smcogs
  SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0001639.3 |  | 0.41 | ribosomal | klebsidin | Klebsiella pneumoniae
BGC0000504.5 |  | 0.40 | ribosomal | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.5 |  | 0.40 | ribosomal | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000538.3 |  | 0.36 | ribosomal | nisin Z | Lactococcus lactis
BGC0000521.3 |  | 0.36 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000551.5 |  | 0.36 | ribosomal | SapB | Streptomyces coelicolor A3(2)
BGC0000513.3 |  | 0.35 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000501.3 |  | 0.35 | ribosomal | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0002698.2 |  | 0.35 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002306.2 |  | 0.42 | ribosomal | freyrasin | Paenibacillus polymyxa ATCC 842
BGC0001639.3 |  | 0.41 | ribosomal | klebsidin | Klebsiella pneumoniae
BGC0000504.5 |  | 0.40 | ribosomal | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000500.5 |  | 0.40 | ribosomal | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000538.3 |  | 0.36 | ribosomal | nisin Z | Lactococcus lactis
BGC0000521.3 |  | 0.36 | ribosomal | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000551.5 |  | 0.36 | ribosomal | SapB | Streptomyces coelicolor A3(2)
BGC0000513.3 |  | 0.35 | ribosomal | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000501.3 |  | 0.35 | ribosomal | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0002698.2 |  | 0.35 | ribosomal | phaeornamide | Pseudophaeobacter arcticus DSM 23566

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.81 out of 30.25
Confidence: medium
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.73 out of 24.78
Confidence: medium
Additional weak hits (2):
BldD
Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 18.41 out of 23.43
Confidence: weak
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 15.78 out of 18.46
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
ColR | Phenol-responsive regulator
LexA variant 2 | Repressor of DNA damage response

NZ_PNGD01000002.1 - Region 1 - RaS-RiPP,furan
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 272 - 37,768 nt. (total: 37,497 nt) Show pHMM detection rules used
Region on contig edge.
furan: (mmyO or AvrD)
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: oxidoreductase
CJ239_RS01125: FAD dependent oxidoreductase

smcogs
  SMCOG1103: FAD dependent oxidoreductase

Transferases: kinase
CJ239_RS01120: glycerol kinase

smcogs
  SMCOG1210: glycerol kinase

Hydrolases: hydrolase
CJ239_RS01100: isochorismatase

smcogs
  SMCOG1027: isochorismatase

Ligases: ligase
CJ239_RS01170: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | furan | RaS-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001249.5 |  |  | 0.26 | NRPS | dimethylcoprogen | Alternaria alternata
BGC0001240.4 |  |  | 0.26 | NRPS | serinocyclin A, serinocyclin B | Metarhizium robertsii
BGC0000357.5 |  |  | 0.26 | NRPS | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001261.3 |  |  | 0.26 | NRPS | AM-toxin | Alternaria alternata
BGC0001641.4 |  |  | 0.25 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002164.2 |  |  | 0.24 | NRPS | peramine | Epichloe festucae
BGC0001209.3 |  |  | 0.24 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001268.4 |  |  | 0.22 | NRPS, PKS | fusarin C | Fusarium fujikuroi
BGC0002287.2 |  |  | 0.21 | NRPS | mutanocyclin, leuvalin, tyrvalin | Streptococcus mutans
BGC0002710.2 |  |  | 0.20 | NRPS | metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid | Metarhizium robertsii ARSEF 23

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001249.5 |  | 0.60 | NRPS | dimethylcoprogen | Alternaria alternata
BGC0001240.4 |  | 0.59 | NRPS | serinocyclin A, serinocyclin B | Metarhizium robertsii
BGC0000357.5 |  | 0.59 | NRPS | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001261.3 |  | 0.59 | NRPS | AM-toxin | Alternaria alternata
BGC0001641.4 |  | 0.58 | NRPS | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002164.2 |  | 0.58 | NRPS | peramine | Epichloe festucae
BGC0001209.3 |  | 0.58 | ribosomal | streptide | Streptococcus thermophilus LMD-9
BGC0001268.4 |  | 0.54 | NRPS, PKS | fusarin C | Fusarium fujikuroi
BGC0001929.2 |  | 0.54 | ribosomal | WGK | Streptococcus ferus
BGC0002583.2 |  | 0.50 | ribosomal | tryglysin B | Streptococcus mutans UA159

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.03 out of 26.06
Confidence: strong
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.31 out of 18.46
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.88 out of 27.78
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.38 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.67 out of 26.06
Confidence: medium
MexT
Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 18.82 out of 21.84
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.53 out of 28.19
Confidence: medium
Additional weak hits (1):
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.69 out of 30.25
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
MexT | Global virulence regulator
MogR | Repressor of flagellar motility genes
RpoN | Regulator of nitrogen assimilation and virulence
ZuR variant 1 | Zinc-responsive repressor

NZ_PNGD01000003.1 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 103,266 - 144,438 nt. (total: 41,173 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: reductase
CJ239_RS02670: hydroxymethylglutaryl-CoA reductase

smcogs
  SMCOG1187: hydroxymethylglutaryl-CoA reductase

Transferases: formyltransferase methyltransferase phosphotransferase
CJ239_RS02590: methyltransferase

smcogs
  SMCOG1248: methyltransferase

CJ239_RS02635: methionyl-tRNA formyltransferase

smcogs
  SMCOG1228: methionyl-tRNA formyltransferase

CJ239_RS02685: Glucose-specific phosphotransferase enzyme IIA

smcogs
  SMCOG1145: Glucose-specific phosphotransferase enzyme IIA

Hydrolases: hydrolase
CJ239_RS02580: isochorismatase

smcogs
  SMCOG1027: isochorismatase

Ligases: synthase
CJ239_RS02665: hydroxymethylglutaryl-CoA synthase

smcogs
  SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001521.3 |  | 0.41 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002561.3 |  | 0.40 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000205.3 |  | 0.40 | PKS | bryostatin | Candidatus Endobugula sertula
BGC0000706.3 |  | 0.39 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000820.5 |  | 0.39 | other (other) | physostigmine | Streptomyces griseofuscus
BGC0002690.2 |  | 0.37 | other (other) | FW0622 | Verrucosispora sp. FIM060022
BGC0001080.5 |  | 0.37 | other (phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0002387.2 |  | 0.37 | PKS | yangpumicin A | Micromonospora yangpuensis
BGC0000286.3 |  | 0.36 | PKS | viguiepinol | Streptomyces sp. KO-3988
BGC0000019.5 |  | 0.36 | PKS | angolamycin | Streptomyces eurythermus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001521.3 |  | 0.41 | NRPS | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0002561.3 |  | 0.40 | other (other) | phenazine SA, phenazine SB, phenazine SC | Streptomyces sp.
BGC0000205.3 |  | 0.40 | PKS | bryostatin | Candidatus Endobugula sertula
BGC0000706.3 |  | 0.39 | saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000820.5 |  | 0.39 | other (other) | physostigmine | Streptomyces griseofuscus
BGC0002690.2 |  | 0.37 | other (other) | FW0622 | Verrucosispora sp. FIM060022
BGC0001080.5 |  | 0.37 | other (phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0002387.2 |  | 0.37 | PKS | yangpumicin A | Micromonospora yangpuensis
BGC0000286.3 |  | 0.36 | PKS | viguiepinol | Streptomyces sp. KO-3988
BGC0000019.5 |  | 0.36 | PKS | angolamycin | Streptomyces eurythermus

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.12 out of 23.79
Confidence: medium
CcpA
Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.53 out of 20.97
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.40 out of 30.25
Confidence: medium
Additional weak hits (7):
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.54 out of 32.74
Confidence: weak
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 21.76 out of 26.06
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.52 out of 31.73
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 21.39 out of 30.12
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 21.73 out of 29.25
Confidence: weak
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 22.18 out of 29.25
Confidence: weak
NuR
Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.00 out of 30.98
Confidence: weak
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CcpA | Catabolite control protein A
ColR | Phenol-responsive regulator
IolR | Regulator of the inositol catabolism

NZ_PNGD01000009.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 67,002 - 79,155 nt. (total: 12,154 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002579.2 |  | 0.48 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0002577.2 |  | 0.46 | ribosomal | lactococcin G | Lactococcus lactis
BGC0000617.5 |  | 0.45 | ribosomal | coagulin | Bacillus coagulans
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000624.3 |  | 0.42 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002005.2 |  | 0.40 | ribosomal | RaxX | Xanthomonas oryzae pv. oryzae
BGC0000619.3 |  | 0.39 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.39 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.39 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0001887.3 |  | 0.38 | ribosomal | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002579.2 |  | 0.48 | ribosomal | carnobacteriocin XY | Carnobacterium maltaromaticum
BGC0002577.2 |  | 0.46 | ribosomal | lactococcin G | Lactococcus lactis
BGC0000617.5 |  | 0.45 | ribosomal | coagulin | Bacillus coagulans
BGC0000558.5 |  | 0.42 | ribosomal | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000624.3 |  | 0.42 | ribosomal | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0002005.2 |  | 0.40 | ribosomal | RaxX | Xanthomonas oryzae pv. oryzae
BGC0000619.3 |  | 0.39 | ribosomal | gassericin T | Lactobacillus gasseri
BGC0001602.3 |  | 0.39 | ribosomal | gassericin-T | Lactobacillus gasseri
BGC0001388.3 |  | 0.39 | ribosomal | gassericin E | Lactobacillus gasseri
BGC0001887.3 |  | 0.38 | ribosomal | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.28 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.97 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.28 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.28 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.97 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.13 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.31 out of 26.06
Confidence: medium
SypG
Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.81 out of 29.25
Confidence: medium
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 23.31 out of 24.78
Confidence: strong
LexA variant 2
Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 22.76 out of 24.78
Confidence: strong
Additional weak hits (3):
ClgR
Description: Caseinolytic protease gene regulator
Species: Corynebacterium glutamicum ATCC 13032
Score: 20.85 out of 30.22
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 22.03 out of 29.65
Confidence: weak
CsoR
Description: Copper-responsive repressor
Species: Streptomyces lividans
Score: 20.83 out of 32.38
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
LexA variant 2 | Repressor of DNA damage response
MogR | Repressor of flagellar motility genes
SypG | Regulator of biofilm formation and host colonization