LOCUS       NZ_CP021011            20741 bp    DNA     circular CON 17-JAN-2024
DEFINITION  Bacillus velezensis strain GFP-2 chromosome, complete genome.
ACCESSION   NZ_CP021011
VERSION     NZ_CP021011.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 3975220)
  AUTHORS   Sun,C.
  TITLE     Complete genome sequence of Bacillus sp. GFP-2, an antibacterium
            strain isolated from shark gut
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3975220)
  AUTHORS   Sun,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2017) College of Life Science, Zhejiang
            University, 866 YuHangTang Road, HangZhou 310058, China
COMMENT     ##MIGS-Data-START##
            alt_elev                          :: not reported
            assembly                          :: not reported
            collection_date                   :: 01-Oct-2016
            country                           :: China
            depth                             :: Not reported
            environment                       :: Shark intestine
            investigation_type                :: bacteria_archaea
            isol_growth_condt                 :: 10-40degC; 1% NaCl; ph 7
            lat_lon                           :: not reported
            project_name :: Genome sequence of Bacillus sp. GFP-2
            sequencing_meth                   :: A pacbio RS II platform
            num_replicons                     :: 1
            Estimated size                    :: "3,975,220 bp"
            ref_biomaterial                   :: GFP-2 = CGMCC 13337
            trophic_level                     :: Chemoorganotroph
            rel_to_oxygen                     :: Aerobic
            Library reads sequenced :: The large smrtbell gdna protocol (Pacific
            Biosciences, USA)
            Assembly method :: De novo assembled using the PacBio hierarchical
            genome assembly process (HGAP)/Quiver software
            Estimated error rate :: 99.99 % (average reference consensus)
            Method of calculation :: Estimation from HGAP Assembly quality
            scores
            Assembly name :: HGAP Assembly version 2 (Pacific Biosciences, USA)
            finishing_strategy                :: not reported
            biotic_relationship               :: free-living
            ##MIGS-Data-END##
            ##Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Coverage                          :: 247.76
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 08:46:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,936
            CDSs (total)                      :: 3,818
            Genes (coding)                    :: 3,738
            CDSs (with protein)               :: 3,738
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 52 of 80
            Pseudo Genes (incomplete)         :: 49 of 80
            Pseudo Genes (internal stop)      :: 17 of 80
            Pseudo Genes (multiple problems)  :: 31 of 80
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:25:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2993981
            Orig. end                         :: 3014722
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20741
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20741
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20741
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10741](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10741
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    906..921
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.1"
                     /tool="antismash"
     misc_feature    complement(1026..1040)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.88"
                     /tool="antismash"
     misc_feature    complement(2333..2347)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            2858..3151
                     /locus_tag="B6257_RS15515"
                     /old_locus_tag="B6257_15435"
     CDS             2858..3151
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015388462.1"
                     /locus_tag="B6257_RS15515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15435"
                     /product="hypothetical protein"
                     /protein_id="WP_101562876.1"
                     /transl_table=11
                     /translation="MADSAEGTCELCGRHLVRLTEHHLTPKEEGGTFLPTAMLCIPCHK
                     QVHALYTNQELAARLAGIEELRRDPKLARFVKWIRKQPPEKLVKTKKANERK"
     gene            complement(3195..3413)
                     /locus_tag="B6257_RS15520"
                     /old_locus_tag="B6257_15440"
     CDS             complement(3195..3413)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003155143.1"
                     /locus_tag="B6257_RS15520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15440"
                     /product="spore germination protein"
                     /protein_id="WP_003155143.1"
                     /transl_table=11
                     /translation="MPAITGPIAINSISGGVVNFGDSFYLSPKSSSKSALGSGAGNTGD
                     FLLLNNVVNATNYIDPDVSDQNVVGNA"
     gene            complement(3453..3848)
                     /locus_tag="B6257_RS15525"
                     /old_locus_tag="B6257_15445"
     CDS             complement(3453..3848)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007610514.1"
                     /locus_tag="B6257_RS15525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15445"
                     /product="spore germination protein GerPE"
                     /protein_id="WP_101562877.1"
                     /transl_table=11
                     /translation="MLKRISRLRNAKINSVGIASVFQAGDTNEINMRIKVLADQRSLAV
                     YRDDEGSFNKKEYQIFRQPAVMPLPETGVQSAFCHENPSIQVRNVKVQGVSSASVVQIG
                     STSVVLGDSRLKHIRQIFTPSSQSQQP"
     gene            complement(3848..4024)
                     /locus_tag="B6257_RS15530"
                     /old_locus_tag="B6257_15450"
     CDS             complement(3848..4024)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388950.1"
                     /locus_tag="B6257_RS15530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15450"
                     /product="hypothetical protein"
                     /protein_id="WP_003155141.1"
                     /transl_table=11
                     /translation="MIFTVINRNIEVGDIRSTGVSSSSLLLIGDTDSVYLSSIFDTPPE
                     SLIIGPYVPLAPE"
     gene            complement(4021..4638)
                     /locus_tag="B6257_RS15535"
                     /old_locus_tag="B6257_15455"
     CDS             complement(4021..4638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388951.1"
                     /locus_tag="B6257_RS15535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15455"
                     /product="spore germination protein GerPC"
                     /protein_id="WP_031378472.1"
                     /transl_table=11
                     /translation="MYDQSVSSYLQNLNSFVQQQAQQIQELERQLKEFQNEISTLKQQP
                     STRIDRLEYKFDQLKIERLEGTLNIGLNPTDPNAVQNFEVGQTSPQVGMMQQEQAGQQM
                     QQIRQNVDMYLNEEIPALLEQLETQYESRLDEANKYHIIEDIRKQMDSRIQYYLSHVPK
                     EENTAPAQYAEQIAEHVKRDIVRAVEHFIKHIPGEMKGDDPS"
     gene            complement(4674..4910)
                     /locus_tag="B6257_RS15540"
                     /old_locus_tag="B6257_15460"
     CDS             complement(4674..4910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015483061.1"
                     /locus_tag="B6257_RS15540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15460"
                     /product="spore germination protein GerPB"
                     /protein_id="WP_003155138.1"
                     /transl_table=11
                     /translation="MNFYVNQSIHINYMRVESVSNSSILQIGSAGSIKSLSNLYNTGSY
                     VEPAPPVTAGQQAVTTGGGPGTSSFVPLQPPSR"
     misc_feature    complement(4876..4889)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 23.16"
                     /tool="antismash"
     gene            complement(4923..5144)
                     /locus_tag="B6257_RS15545"
                     /old_locus_tag="B6257_15465"
     CDS             complement(4923..5144)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388953.1"
                     /locus_tag="B6257_RS15545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15465"
                     /product="spore germination protein"
                     /protein_id="WP_003155135.1"
                     /transl_table=11
                     /translation="MPAIVGAFKINAVGTSGVVHIGDCITISPKAEVKTFAGAGSFNTG
                     DNLTLTNYRNSTNVYDNDVIDQPMAGNA"
     gene            complement(5334..5543)
                     /locus_tag="B6257_RS15550"
                     /old_locus_tag="B6257_15470"
     CDS             complement(5334..5543)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417420.1"
                     /locus_tag="B6257_RS15550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15470"
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_025649564.1"
                     /transl_table=11
                     /translation="MNKIEEKRLTLFETAQKFGINATETIRCSQELDSLLNGCRGGLIQ
                     QTKDSGPNPAAQIQHGREKKEAFS"
     misc_feature    5622..5642
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: medium, score: 26.99"
                     /tool="antismash"
     gene            5759..6664
                     /locus_tag="B6257_RS15555"
                     /old_locus_tag="B6257_15475"
     CDS             5759..6664
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388956.1"
                     /locus_tag="B6257_RS15555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15475"
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_003155130.1"
                     /transl_table=11
                     /translation="MKFATGELNSRKFVGLIIDDDKILDLQKAEKKLFELETIPGSLIE
                     CIQKGDKFVAHAGQLAEWAKKPNDESGSFMYALSDVKLCAPIPRPSKNVICIGKNYRDH
                     AVEMGSEADIPEHPMVFTKAPAAVTGHGETVKSHLDVTEQLDYEGELAVIISKSGSHIS
                     KEHALDHIFGYTIVNDITARDLQKKHKQFFIGKSLDTTCPMGPVIVHKSAVSDPQSLKV
                     ETRVNGELRQSGSTGDMIFPIAELIETLSKGMTLEAGDIIATGTPSGVGKGFKPPKFLK
                     PGDRIDITIEPIGTLSNQIG"
     gene            6758..7114
                     /locus_tag="B6257_RS15560"
                     /old_locus_tag="B6257_15480"
     CDS             6758..7114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388957.1"
                     /locus_tag="B6257_RS15560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15480"
                     /product="YisL family protein"
                     /protein_id="WP_003155128.1"
                     /transl_table=11
                     /translation="MTHWHITSWVVALILVFVSYGLYGAGKAKGAKITHMILRLFYIII
                     ILTGAELFVRFANWNGEYAGKMLLGIITIGLMEMLVIRKKKGKSTGGLWIGFIIVLVLT
                     VLLGLHLPIGFHVF"
     gene            complement(7356..7898)
                     /locus_tag="B6257_RS15570"
                     /old_locus_tag="B6257_15490"
     CDS             complement(7356..7898)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417377.1"
                     /locus_tag="B6257_RS15570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15490"
                     /product="DUF2777 family protein"
                     /protein_id="WP_199445933.1"
                     /transl_table=11
                     /translation="MKRKQLFSEKNKWGRGTLMIEGGICLVENDEGDILLADSLGNAAV
                     LLKRDGRWQPARICGGSAEIGADIIPLLGGEEIRYEKAVKRPLLTLLDSLDDETFLLFL
                     SHLHGFGLSVYDCVFSYNQALFSGEGVSFYHFSADDAQCALQHHRGSPGKHDRFEWTAS
                     DGRRSIMYSAAKQDGTA"
     gene            8074..9915
                     /gene="asnB"
                     /locus_tag="B6257_RS15575"
                     /old_locus_tag="B6257_15495"
     CDS             8074..9915
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016938277.1"
                     /locus_tag="B6257_RS15575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15495"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_003155123.1"
                     /sec_met_domain="GATase_7 (E-value: 5.7e-48, bitscore:
                     159.7, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-99, bitscore:
                     331.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIAGWVDFQKQLVQEKHIMNNMIDTLSKRGPDDSNVWGEPHVL
                     FGHKRLSVVDIEGGRQPMACTHQEETYTIIYNGELYNTEELRKELQARGHRFERTSDTE
                     VLLHSYIEWREECVDRLNGIFAFAIWDEKRKRLFGARDRLGVKPFFYKEHGSSFLFGSE
                     LKAILAHPDVKARTDSGGLAEVFGLGPSRTPGCGVFKGIHEVRPAHAFTFSKDGLSIWR
                     YWNVKSEKHTDSFDETAAHIRYLFQDAVTRQLVSDVPVCTFLSGGLDSSAITAIAAAHF
                     EKQGRDPLHTYSIDYEENSKFFKASAFQPNDDGPWIDKMTNAFGTQHHKCVITQDQLVE
                     HLEESVLVRDLPGMADVDSSLLWFCREIKKDFVVSLSGECADEIFGGYPWFHTAAEEDG
                     FPWMRSTEERVTLLDEKWQKRLNLREYVNARYEETIAETPLLDGETGTDKARRQLFYLN
                     MLWFMTNLLDRKDRMSMGASLEVRVPFADHRLVEYVWNIPWEMKMHGSREKGILRKALE
                     GLLPEDILYRKKSPYPKTHHPKYTQGVTEWLKTILQQKDSVLHTLLDRKKLEMLLETEG
                     SSFQVPWFGQLMKGPQLIAHLAQIHTWFEAYRIDIEE"
     gene            10001..10741
                     /locus_tag="B6257_RS15580"
                     /old_locus_tag="B6257_15500"
     CDS             10001..10741
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417379.1"
                     /locus_tag="B6257_RS15580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15500"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_071392015.1"
                     /sec_met_domain="phytoene_synt (E-value: 7e-22, bitscore:
                     75.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.2e-29,
                     bitscore: 98.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYETCAQLAEAHFPLYKRTFSSLPPKNRRAAWAVLALFHEADR
                     LDVQELGGFEQAAQDFLNGARADGFLWEALTDVRQQFALEEEPLREFIAGHISDREKVT
                     YQEFDDLLMYAGQTGGALGLLLLPVCARRNQEKLRHAAVSLGAAIQLTRVLLGIHTDEL
                     AKKRLPRQVMKQFGYTEEELESHTVNKAFMNVWEYIAFEAEAYFEEASEELELFPLYSR
                     PAVTGLLAHYRSELGDMRKRLSQA"
     gene            complement(10778..12145)
                     /locus_tag="B6257_RS15585"
                     /old_locus_tag="B6257_15505"
     CDS             complement(10778..12145)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388962.1"
                     /locus_tag="B6257_RS15585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15505"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_003155121.1"
                     /transl_table=11
                     /translation="MKQAILKRAAFKQSSDHKLSLYALTWPIFIEVSLYMFMGNADTLM
                     LSQYSDNSVAAVGVSNQILNLIIVMFSFIATGTTIVISQFLGSKQKKEAQEVAYVSIGA
                     NFVISLAISAAIFFAAVPLLHVMGLSNELMPDAKVFLQVVGGLSFIQALIMTFSAILKS
                     YGHTKDTMFVTIGMNILNIAGNFLVIFGPLGLPVLGVAGVAMSTSFARIIGLIAMIVIV
                     KKRIGLGLTWQKIFHVHKEHLRKLLKIGIPSAGEQLSYNISQMVVTYFIAIMGAQALTT
                     KVYTQNITMFILLFGTAISQGTQILIGRYIGAKRFDDAYDRCMKSLYWALGIAALTSVI
                     MTLFSKQLIGIFTSSPDIIATASMLIAMTIILEPGRSFNVIIINSLRAAGDAKFPVYMA
                     MISMWGIGLPLAYLFGIHFGLGLMGIWISFIADEWVRGILMYRRWRSRIWIQKGIA"
     misc_feature    12198..12211
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.16"
                     /tool="antismash"
     gene            12268..13131
                     /locus_tag="B6257_RS15590"
                     /old_locus_tag="B6257_15510"
     CDS             12268..13131
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417425.1"
                     /locus_tag="B6257_RS15590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15510"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_031378476.1"
                     /transl_table=11
                     /translation="MSFLEFTVPPFPVFIAAGEGVFKKGETHVRRVFPVFDLLYVKEGV
                     LYITEDENAFSVEAGEYILLSPGLEHYGTKGSEETTSYSWLHFEGADYEVTETTGNNWS
                     ELRRKKGSFEEPSRYRLSLPQKGKVRRPQFMAGQFSVLTDESAENSDLPLRKQILFEEL
                     LLHLQKEAFQIPSAKERVAWEAARYLQEHYQEKTTIKALSSALHYNQDYVTRCMQQVLG
                     VTPGQYTNKVRMTEAKRLLSATNDKMGTIADAIGMEDPTYFSKLFKQIEGISPLEYRKF
                     VSRKTD"
     gene            13167..14192
                     /locus_tag="B6257_RS15595"
                     /old_locus_tag="B6257_15515"
     CDS             13167..14192
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417382.1"
                     /locus_tag="B6257_RS15595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15515"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_101562879.1"
                     /transl_table=11
                     /translation="MKMTIYDVAEKAGVSISTVSRVINNTGRISDKTRRMVLRVMEEMD
                     YHPNVHASALTGKKTNMIGLITPDISNPFFGELVKSIEDSAGVLGFHIIICSTDYQPEK
                     ETKYFSMLRQKQADGIIFATGLDHDDSVTALDDIVKSGIPLAMITQDKPLAPMDVVIIN
                     DFLGGYTAAEHLISLGHERIACIVRNGSTTGERDRIKGFQKALREAGMTLDESLIIPTE
                     YSLESGKQAAGELFDRDLPTAVFAFNDVLSCAAIQAARSRGIRVPEDLSVIGFDNTILA
                     EMTAPPLTTISQPIREMGRRVVELLIDEIQGKKKTKSKIILSPELVIRHSTAPVKTRPQ
                     R"
     misc_feature    14210..14224
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    14240..14256
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.44"
                     /tool="antismash"
     gene            14419..15450
                     /gene="iolG"
                     /locus_tag="B6257_RS15600"
                     /old_locus_tag="B6257_15520"
     CDS             14419..15450
                     /EC_number="1.1.1.18"
                     /GO_function="GO:0050112 - inositol 2-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417427.1"
                     /locus_tag="B6257_RS15600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15520"
                     /product="inositol 2-dehydrogenase"
                     /protein_id="WP_101562880.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4.4e-33, bitscore:
                     112.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.3e-26,
                     bitscore: 90.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQVRCAVLGLGRLGYFHAKHLAGEVRGAELAAVCDPMKGKAEA
                     CAKELGIAKWTESPYELLEDHTIDAVIIVTPTSTHAEMIMKAAQNGKHIFVEKPLTLSL
                     EESIKVMKKIEETDVICQVGFMRRFDPAYADAKRRIDAGEIGRPIYYKGFTRDQGAPPA
                     EFIKHSGGLFIDCSIHDYDIARYLMNAEVTSVSGHGRVLKHPFMEECGDVDQALTYLEF
                     DSGAAGDVEASRNSPHGHDIRAEIIGTAGSILVGTLRNSHVTILTESGSSYEIIPDFQA
                     RFKDAYRLELEHFAECVKKGETPIVTDIDAAINLEIGIAATESFKTGRPVKLTPGAPNY
                     AGL"
     gene            complement(15496..15990)
                     /locus_tag="B6257_RS15605"
                     /old_locus_tag="B6257_15525"
     CDS             complement(15496..15990)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1250: DinB"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015239546.1"
                     /locus_tag="B6257_RS15605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15525"
                     /product="DinB family protein"
                     /protein_id="WP_101562881.1"
                     /transl_table=11
                     /translation="MSDILKLYHYHRWANEQVIQHLKTLPAASLQQKLDSVFPTVNAVL
                     VHIYRADYIWLHVLYGETYEQIVSQFDQFEKLDGDFEAVEHRMTELDKEYSEFLRDLEN
                     MEGPISISHPRMGTLRTTYADVIRHIVNHGTYHRGNISAMLHQMGYKGVPTDYIFFSYE
                     S"
     gene            complement(16045..16653)
                     /locus_tag="B6257_RS15610"
                     /old_locus_tag="B6257_15530"
     CDS             complement(16045..16653)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417385.1"
                     /locus_tag="B6257_RS15610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15530"
                     /product="LysE/ArgO family amino acid transporter"
                     /protein_id="WP_058906696.1"
                     /transl_table=11
                     /translation="MNAILHGVMLAFGLILPLGAQNVFIFQQGAWQKHVWQAFPAVIAA
                     AVCDTILISAAVAGVSMIIAEIPVFQTVMLIGGFLFLSFLGWQTWRSKPQAEQAKKTVF
                     TAKKQAVTAAMVSLLNPHAILDTVSVIGTSSAAYPGIDKWLFAGACIMVSWVWFAGLAF
                     AGRLVQTADTGGRLLGILNQCSALVMWGAAFYFAALLFR"
     misc_feature    16613..16628
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.61"
                     /tool="antismash"
     gene            16779..18221
                     /locus_tag="B6257_RS15615"
                     /old_locus_tag="B6257_15535"
     CDS             16779..18221
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (119-467). E-value:
                     2.2e-32. Score: 104.5. Matches aSDomain:
                     nrpspksdomains_B6257_RS15615_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417386.1"
                     /locus_tag="B6257_RS15615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15535"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_101562882.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-30, bitscore:
                     104.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSWRPDRESHIPLYLQIEQHIKEKILHGEWTIGTKIPSQRKLAE
                     ELQVNRSTVTAAVDELIAQGLLEGKRGGGTKVVNNTWSIMAAAKPLDWSTYVTSGSHQP
                     NSPLIQAINQNEPRPDLIRLGTGELSQELLPEQEMGELFREAGTNIFALGYEEPKGSLQ
                     LRQSVAEHLKTKGIHASPASIVIVSGALQALQLISIGLLKPNSVMLTENPSYLHSLRVF
                     QSAGVKLKGVPMDESGIKTDHLPDYRRQYEAGLLYTIPSFHNPTGTVMSLKRRKELITL
                     ARNHRLPVIEDDAYGDIWIDKEPPPPLKSMDGEGNVLYIGTLSKTVSPGLRIGWVVAPE
                     PVADRLADIKMQTDYGSSALSQWAACQWLSSGRYEARLLRLRKELKIRRDAALCFLERY
                     AGDIAEWRVPEGGFYIWVTFHKAFAVQTLFTRALESGVLINPGALYLPEDRQSLRLSYS
                     YASLPDLEKGIQTIADIARRFV"
     aSDomain        17136..18179
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_B6257_RS15615_Aminotran_1_2.1"
                     /evalue="2.20E-32"
                     /label="B6257_RS15615_Aminotran_1_2.1"
                     /locus_tag="B6257_RS15615"
                     /protein_end="467"
                     /protein_start="119"
                     /score="104.5"
                     /tool="antismash"
                     /translation="DLIRLGTGELSQELLPEQEMGELFREAGTNIFALGYEEPKGSLQL
                     RQSVAEHLKTKGIHASPASIVIVSGALQALQLISIGLLKPNSVMLTENPSYLHSLRVFQ
                     SAGVKLKGVPMDESGIKTDHLPDYRRQYEAGLLYTIPSFHNPTGTVMSLKRRKELITLA
                     RNHRLPVIEDDAYGDIWIDKEPPPPLKSMDGEGNVLYIGTLSKTVSPGLRIGWVVAPEP
                     VADRLADIKMQTDYGSSALSQWAACQWLSSGRYEARLLRLRKELKIRRDAALCFLERYA
                     GDIAEWRVPEGGFYIWVTFHKAFAVQTLFTRALESGVLINPGALYLPEDRQSLRLSYSY
                     ASLPDLEK"
     gene            complement(18229..18855)
                     /locus_tag="B6257_RS15620"
                     /old_locus_tag="B6257_15540"
     CDS             complement(18229..18855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003155116.1"
                     /locus_tag="B6257_RS15620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15540"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_101562883.1"
                     /transl_table=11
                     /translation="MNTIQKPKIPKELPVLSFTEALQDEELKEVIIENGIVNGKLDGLR
                     AEKVIFRNIVFTDISFRHMECTDVLFDKCDVSNADFSESIIHRTAFQHSKLLGLNLADS
                     AMRHVRFEDCLANYSSFSYSNMKHVRFDSCGLSESEWNDSVLEYTDLDVCDLNGANFIG
                     TSLFNMDISTCTFDHLHVSLDKLKGCRISPAHAATFAEALGAIVT"
     misc_feature    complement(18903..18914)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.44"
                     /tool="antismash"
     gene            complement(19054..19494)
                     /locus_tag="B6257_RS15625"
                     /old_locus_tag="B6257_15545"
     CDS             complement(19054..19494)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012117261.1"
                     /locus_tag="B6257_RS15625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_15545"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_071392011.1"
                     /transl_table=11
                     /translation="MVEVKPITAEDTYAIRHSVLRPHQTIEDCKYDQDSVEGAFHLGGF
                     YDGTLISIASFYPQNQQALQAAPAYQLRGMATLEEYRTQKAGSTLIAYAERKLADMGAA
                     LVWCNARCHVKGYYEKLGWKSTGSPFDIPGIGPHVIMYKELA"
ORIGIN
        1 aaaattgcgg cggcgggcgc aggaagcggc agcgaaaaaa aatgaaatgc tggccgaaca
       61 atccggcctc ggagacgcag gagaagatgc gctgaagcag gctgaacagc agtttcacga
      121 agcgaacgaa cggcttgaag cagctgagaa gaaacgggtc cgggcaaaag agcgttttga
      181 aaatcaccag gaaatttgga acttgcagac agaaagagat gagtatgagc gccgggagaa
      241 aaagcttgag gaaagacgcc cgtacatcac ggatttgact gagcgtctta aagaggcgga
      301 aacagctctc gcccttgagc cgtacgcaga ccgctgcaca gaagccgtcc gccggaagca
      361 gcgcgccgaa caggaacacg aactggccaa acggaaatca gaggcagaaa ccgtttcatt
      421 tacccggcaa aatgaagcct atgaagcatg gcgggcccat aaggccgaac aggagccgaa
      481 gcttgtcaag gaagaagagc tgtatcaaag actttcagcc attgaacaaa aactgcttga
      541 agcgaaaaaa gaagcggaaa aaacaaatgc ggagcacagc aaaaaagagg aagaatacga
      601 agccgcctcg aaacagctga ccgcagtgaa agaccgcctg acccgcggcc aaaacaggca
      661 gaatgagctg aaagaagagc tgaaagcagt tcaagtgacc gccgatgaac ggaaaaaatg
      721 ccagaccgca gcacagctgg cggcaggctt tcagcagaca caggaacaaa tcacgaaaga
      781 gcgggccaat ctgacaacgc agctgaaaaa cgtggagaag ctcaacggag aaagcgagtc
      841 gctcacagcg aaagcgaaaa cggaagagga agacattacg cgcgcttatc aaacgcttca
      901 aaccgtttac catatggtct gtgaaacgga acgttcactg aaagccgcag ccgaacgggc
      961 tgaaaaaacg caagccgatc tccgcaggcg ctcagaggaa gcgagaacag ctgcattaac
     1021 aaaagaatta tcggaaaaac tgatcgaagg aaagccttgt cctgtatgcg gctcgacgca
     1081 gcatgaccgc ccgcgttccg ctcatgaaac attctcgcct gatacggctg tgcaggaaca
     1141 tttgcagcag gtggaagcgc tgctttctga ggcggcggct ctttctcagg aagtgctgac
     1201 agccaaggtt gcattagaag aacagtcggg gcgttttacc gaagaatgtc cgtttctgca
     1261 aagcgcccgg gttccggagc tggaagccgc ttcttccatc agcggacgcc cgcttgatga
     1321 agcgttcagc gccgtccgct tggaatggaa acaaatgaaa caggatatgc tgtcggtaaa
     1381 agagaaggtc acaagactga tcagcgcgca tcagcagacg gtaaaacaag ctgagcagct
     1441 tgccgaacga acccgctacg aggaaaaaga agccgaccgt ctcagacatt cattagaaga
     1501 gcttgaatcg ctgtcagaaa gccgattgaa tcagtacaac gaagtctgcg gtgatattcc
     1561 gccaaaccgg attgacgcct ggcaggcttc gatagatgag aaggacaggc aggcagaaga
     1621 atgtgagaag cgcattgaaa caagcatcgc attcctcaag gaacatgaag aggagaaaga
     1681 acgcctgcag gagatgaagc atcggcttga acgggaacgg ctcgagcttc actatgcgtc
     1741 tgagcgcctg cagcaggtga ttgacggata tgaacaagag ctcggaacag cagctgaaga
     1801 aacatcaatt tccgcaaagc ttgaagcggt gcggcaggaa ttacagctgt taaaatcaaa
     1861 agaacagtcc ctattcgatg cgctgaagca ggcgcagcaa tcactgaatg atgcaaaagg
     1921 ccgggaatca gggagtctca tgtcactcag ggatgctgag gcttctcttg agaaagcgca
     1981 aaacgactgg cgcgtgaggt caaaagaaac cgggtttacc gaaccggacc aagttaaaaa
     2041 aagtctgctt ccgcaagggc gtgcagagga aatgaaaaaa gaaattgatg agtttctgga
     2101 cacctcaaaa cagctatcgg caaatatcag ccgtgttact gataaattag ccgagcgccg
     2161 gatatcggag gaagaatgga cagcatccgt ttctctgctg aagcaggcag aggctgagtc
     2221 aggcgccgcc atggaggaaa aaggagcaca ggcaaaagcc tacgcggtta tgcaaaaaca
     2281 gcataagcgc tttaaagaga ttgaagccga actgaaaagc tggcagacac agattgacag
     2341 gcttgataag ctccagtctg tatgtaaagg caatacattc gtcgaatttt tagcggaaga
     2401 acagctggaa agcgtggctc gggacgcctc tgcccgtctc ggagcgctga caaggcagcg
     2461 gtatgccata ttagtcgatt cagaaggcgg tttcgtcatg cgtgatgacg cgaacggagg
     2521 cgtcaaacgg cccgtatcaa gcctttccgg cggggagacg tttctgacat cgctgtcgct
     2581 tgcgcttgcc ttgtccgccc agattcagct gcgggggcaa tacccgctgc aattcttttt
     2641 cttagatgaa ggattcggga ctcttgacca agggctctta gacaccgttg tcacagcgct
     2701 cgaaaagctg caatcggaca acttatccgt cggagtgatc agccatgtgc aggagctgag
     2761 agcgcgtctg ccgaaaaaat taatcgttca tccgtccgaa ccgggcggga aaggcacccg
     2821 ggtcacattg gagatcatgt agaaaggaga aggaattatg gccgattctg ccgagggcac
     2881 atgtgaatta tgcggccgcc atcttgtgcg gctgacggag caccacttaa cgcctaagga
     2941 agaaggcggg acattccttc cgaccgcaat gctctgcatc ccttgtcata aacaggttca
     3001 cgcgctctat acgaatcagg agcttgcggc aaggctcgcg ggaatagaag aactgcggcg
     3061 tgacccgaaa ctcgcgcggt ttgtgaaatg gatcagaaaa cagccgccgg aaaagcttgt
     3121 aaaaacaaaa aaagcaaatg aacgaaaata acgctgaacc aaaagcagcc ctcttctgaa
     3181 agagcggctg ctttttaggc gtttccgacc acattttgat cgctgacatc ggggtctata
     3241 tagtttgtcg cattgacaac gttgtttaat aacaggaaat ctccggtatt gcctgctccc
     3301 gaaccgagcg cagatttaga agagcttttt ggagaaaggt aaaaggaatc accaaagttt
     3361 acgactccgc ccgatatgga attgatagct ataggtccgg taattgctgg cataaacgac
     3421 accctttata gaagtctcac cgtcattata tgtcagggct gctgtgattg tgagcttggc
     3481 gtgaagatct gcctaatatg tttcagccgc gaatctccca gaacgaccga cgtcgatccg
     3541 atttgaacca cggacgctga cgatacccct tgaactttta catttcttac ctgaattgaa
     3601 gggttttcat ggcagaatgc gctttggact cctgtttccg gtaacggcat gacggccggc
     3661 tgccgaaaga tctggtattc ttttttgtta aatgagcctt catcatctct gtatacagca
     3721 agactacgct gatcggccaa tactttgatc cgcatattga tttcattcgt atcgcctgct
     3781 tgaaagacac tcgcaatccc gactgaattg atcttggcgt tccggaggcg tgaaatgcgc
     3841 tttaacatta ttccggcgcc agcggcacat aaggcccgat aataagagat tccggaggcg
     3901 tgtcaaagat ggaagacaga tagacggaat cggtgtcgcc gattaataat aaggaagaac
     3961 tggatacacc ggtagaccgg atgtcgccga cttcaatatt ccggttaatc actgtaaaaa
     4021 tcatgacgga tcatcacctt tcatttcacc aggtatgtgt ttaataaagt gctcgacggc
     4081 cctgacaata tcacgcttta catgttcagc aatctgctcg gcatattgcg cgggcgccgt
     4141 attttcttct ttcgggacat gggacagata atactgaatc cggctgtcca tctgctttct
     4201 gatatcttca ataatatgat atttgttcgc ttcgtccagc ctgctctcat actgagtttc
     4261 gagctgctct aaaagcgcgg ggatttcttc attcaggtac atatcgacgt tttgacggat
     4321 ttgctgcatt tgctggcccg cctgttcctg ctgcatcatt ccgacctgcg gagatgtctg
     4381 gccgacttcg aagttttgca cggcattcgg atcagtcgga ttcaatccga tattcagcgt
     4441 tccttccagc cgttcaattt tcagctgatc aaatttatac tcgagccgat caattcttgt
     4501 agaaggctgc tgcttcagcg ttgaaatttc attttggaat tctttcagct gccgttcgag
     4561 ctcctgaatc tgctgcgcct gctgctggac gaaagaattt aaattctgca ggtaggatga
     4621 aacggattga tcatacatga cattcacctc gcgtctcgtt tccttcatta aaactaccgg
     4681 cttggcggct ggagcggtac aaatgatgag gtgccgggac ctccccctgt tgttacagcc
     4741 tgctgccccg cggtgacagg cggcgccggc tcaacataac tccctgtgtt gtacagattg
     4801 gaaagagatt taattgaacc ggcgcttccg atttgcagta tggaggaatt gctgacagat
     4861 tctacacgca tgtaattgat atggatcgac tgattgacgt aaaaattcat acggcgcctc
     4921 ctttatgcgt ttcctgccat cggctgatcg attacatcat tatcgtacac attcgttgaa
     4981 ttcctgtaat tcgtcagtgt gagattgtct ccggtattga agctgcccgc tccggcaaat
     5041 gtcttaacct ctgcttttgg agaaatggtg atgcagtcgc ctatatgaac gactccgctc
     5101 gtaccgacgg cattaatttt aaacgctccg acaattgcgg gcatacgagc acatcctttt
     5161 cgtgaagatt ttcatgactg cactccagga gcttatctgg gctgcctgcc taaaatagct
     5221 tatgacaaat gcacattttt gtgagcggaa aaaactttag acgtaaaaac accggcgctt
     5281 tacgcatgcc gggtcttata cataaatgat acagatttat atacatatca cgtttatgag
     5341 aaagcctctt ttttttcgcg gccgtgctga atctgtgcgg ccgggttcgg cccgctgtct
     5401 ttcgtttgtt ggatgagccc gccccggcac ccgtttaaaa ggctgtccag ctcctggctg
     5461 cacctgatgg tctccgtcgc attgattccg aatttttgcg ctgtctcgaa taaagttaat
     5521 cttttttctt caattttgtt catcgtgtga tctccaattc tcgattattt tggaaaacat
     5581 aggatgataa tagtataacc cattttggcc aagaaggttt tatttcgtca atatgactaa
     5641 aaaattgaca atttttgata ctcttttaca cttattttca gcctgtttaa aagagggatt
     5701 tcccgttcgg aggaagaata cataaaggaa tgccatttaa aaatgatggg ggattaacat
     5761 gaaatttgcg acaggggaac tgaacagccg aaaatttgtc ggtctgatta ttgatgatga
     5821 caaaatctta gatctgcaaa aggctgaaaa aaaattgttt gaacttgaga cgattccggg
     5881 ttcgctgatc gagtgcattc aaaaaggaga taagtttgtc gcgcatgccg gacagcttgc
     5941 ggaatgggcg aaaaaaccga atgacgaatc gggttcattt atgtatgcgc tgtctgacgt
     6001 aaagctttgc gcgcctattc cgagaccttc aaagaacgtg atctgcatcg ggaaaaatta
     6061 tcgtgatcat gccgttgaaa tggggagtga ggcggatata ccggagcatc ccatggtttt
     6121 cacgaaagcc ccggctgccg ttacaggaca cggagaaaca gtgaagagcc acttggatgt
     6181 aacggagcag cttgattatg aaggggagct tgcggtaatc atatcaaaaa gcggatcgca
     6241 catctccaaa gaacatgcgc ttgatcatat attcggctat acaattgtaa atgatatcac
     6301 agcgcgcgat ctgcagaaaa aacataaaca gttttttatc ggcaaaagcc tcgatacgac
     6361 atgcccgatg ggcccggtca ttgtacataa gtcggccgtc agcgatccgc aaagcctgaa
     6421 agttgaaacg cgggtgaacg gtgaactgcg ccaatcagga tcaacgggtg acatgatttt
     6481 tccgatagct gaattaatcg agacgctgtc aaaagggatg acgcttgaag ccggtgacat
     6541 tatagcgacg gggacgccgt ccggtgtcgg aaaaggattt aagccgccga aatttttaaa
     6601 gccgggggac cgcattgaca ttacaattga accgatcggc acgctgtcga accaaatcgg
     6661 ataattgtgt gtctttcgca cgattgataa tgctccgagc ggcttgttgt ggtaccataa
     6721 gtgaggcaga ttgatctgat agggggaatt gaacataatg acacattggc atattacttc
     6781 atgggtcgtt gcgcttatcc tggtgtttgt cagctacggg ctgtacggtg ccggaaaagc
     6841 gaagggcgca aaaattacgc atatgattct gcgcttattc tacattatta ttattctgac
     6901 cggagctgag ctttttgtcc gttttgcgaa ttggaacgga gagtacgccg gaaaaatgct
     6961 gctcggcatc attaccatcg gactgatgga aatgctcgtc atccgtaaga aaaaaggcaa
     7021 atcaaccggc ggactgtgga tcggttttat tatcgtgctc gtcctgacgg tgctgctcgg
     7081 ccttcacttg ccgatcggct ttcacgtatt ttaatcaatc gcttgaaaaa cccggatgca
     7141 tccgggtttt tttagttgcg caactgtgcc gctgaatgag aaatgccgtg ttgatgaggc
     7201 gaaggagatg tgcaggatgc caaaagcgtc aatcaatctc gttatcgcaa aagcttcggc
     7261 tgtgaagggt aaaagcaaac gccggccgtc aatcagcgtg aaaaacaaag ctgaatacat
     7321 caggcggcac ctatttaaaa ggtgccgcct gtttgttacg cggtgccgtc ttgttttgcc
     7381 gctgaataca taatggagcg ccgcccgtca gatgccgtcc attcaaatct gtcgtgttta
     7441 cccgggctgc cgcgatgatg ctgaagggcg cattgtgcgt catccgccga gaagtgataa
     7501 aacgaaacgc cttcaccgga aaacagcgcc tgattgtagg aaaatacgca atcatataca
     7561 gacaggccga acccgtgcag atggctgaga aacagcagaa acgtttcatc gtccagcgaa
     7621 tcgagcaagg ttaacagcgg ccgtttgacc gctttttcat aacggatttc ttccccgccg
     7681 agcaggggga tgatgtctgc gccgatttcg gccgaaccgc cgcaaatccg tgccggctgc
     7741 catcggccgt cgcgtttcaa caatacggct gcgtttccta gactgtctgc aagcaggata
     7801 tcgccttcgt cgttttcgac gaggcagatg ccgccctcta tcatcagggt gccgcgcccc
     7861 catttgtttt tttctgagaa aagctgtttt cgtttcataa ccgtgccggt ctcctttgtt
     7921 tgtttcttct cttccgttct ttccaaatcg ggcttgtctc atacaagtct tagtgggaca
     7981 aatcaactat ctgcgtttct ttgcataaac tgggtaaagt gctgatagaa acgaatttga
     8041 taccgacaga aacgggattg gagctgatat cacatgtgtg gaattgcggg ttgggtcgat
     8101 tttcaaaagc agctcgtcca agagaaacat attatgaaca atatgataga cactctttca
     8161 aaacgagggc ctgatgattc aaacgtctgg ggagagcccc atgttttatt cggacataaa
     8221 agactttcgg tcgttgacat tgaaggcggc cgccagccga tggcctgcac gcatcaagag
     8281 gaaacgtaca ccatcattta taatggcgag ctgtataaca cggaggaatt gcggaaggag
     8341 cttcaggcga ggggccaccg ttttgagagg acctctgata cagaagtgct gctgcacagc
     8401 tatattgagt ggcgggagga gtgcgtggac cgcttgaacg gtattttcgc ttttgccatc
     8461 tgggatgaaa agcgaaagcg gctcttcggg gcaagagacc ggctcggcgt caaaccgttt
     8521 ttttataaag aacacggctc ttcctttctg tttgggtcgg aattgaaagc catccttgct
     8581 catcctgatg tgaaagcccg cacagacagc ggcggacttg cggaagtatt cggactcggg
     8641 ccgtccagaa ctccgggctg cggggtgttt aaaggaattc acgaggtgcg tcccgcccat
     8701 gcgttcactt tctcaaagga cggtttgtcc atatggcgtt attggaatgt aaagagcgaa
     8761 aagcatacag acagcttcga tgaaaccgcc gctcacattc ggtacttatt tcaggatgca
     8821 gtgacacgcc agctcgtatc tgacgtgccg gtttgcacgt ttttatcagg ggggcttgat
     8881 tcgagcgcga taaccgcgat agccgccgct cattttgaga aacaaggaag agatcccctt
     8941 catacttatt caattgatta tgaggagaac agcaaatttt ttaaagcgag cgcctttcag
     9001 ccgaatgatg acggcccgtg gatcgataaa atgacaaatg cattcggcac acagcatcat
     9061 aagtgcgtga ttacgcagga tcagctggtt gaacatctgg aggaatccgt tctcgtcaga
     9121 gacctgccgg gcatggctga tgttgattca tcgctattat ggttctgccg ggaaattaaa
     9181 aaagattttg tcgtgagtct ttccggagaa tgcgcggacg aaattttcgg cggatatccg
     9241 tggtttcaca ccgcggcaga agaagacgga tttccttgga tgaggtcgac tgaggagagg
     9301 gtcacgctct tggatgaaaa gtggcaaaaa cggctgaatc ttagagaata cgtgaatgcg
     9361 agatatgaag aaaccattgc ggaaacgccg ctgttagacg gtgagacggg aacagataaa
     9421 gcgagacggc agctgttcta cttaaatatg ctttggttta tgacaaatct gctcgaccgc
     9481 aaagaccgca tgagcatggg cgcaagtctt gaagtacggg tgccgttcgc cgaccacaga
     9541 cttgtggaat acgtttggaa tattccttgg gaaatgaaaa tgcatggcag ccgggaaaaa
     9601 ggcattttgc ggaaagcgct tgaaggactg cttcctgaag atattttgta ccgcaaaaaa
     9661 agcccatatc cgaaaacgca tcacccgaaa tacacgcagg gggtcacaga atggctgaaa
     9721 acgattttgc aacagaaaga ttccgtgctt cacaccctgc ttgacagaaa gaagctggaa
     9781 atgctgctgg agacagaagg ttcatctttt caggtgccgt ggttcggcca gctgatgaaa
     9841 ggcccgcagc tgatcgccca tcttgcccag atccatacat ggtttgaggc gtaccgtatc
     9901 gatatagaag aataacagtg ccgcgaccgg tttccgctga aggatatcgg tctttttatt
     9961 gtgaaacata tggtacacta aaaaacagag gagtgatacc atgaccgaat atgaaacatg
    10021 cgcccagctt gccgaggcgc actttccttt atataaacgg actttctcat ccctgccgcc
    10081 aaaaaacagg cgggccgcat gggcggtgct tgctttgttt cacgaagctg atcggctcga
    10141 tgtgcaggaa cttgggggat ttgaacaggc ggcacaagac tttctgaacg gggcacgcgc
    10201 cgacggcttt ttgtgggagg cgctcaccga tgtgcggcag caatttgcgc ttgaagaaga
    10261 gccgttgcgt gagtttatcg ccggccacat ctctgacaga gaaaaagtaa cgtatcaaga
    10321 gtttgatgac ctgctgatgt acgcgggcca aacaggcgga gccctcggcc tgcttctgct
    10381 gccggtttgc gcgcgccgga accaagagaa actccgccat gcagccgttt cattaggagc
    10441 agccattcag ctgacccggg tgcttctggg gattcatacg gacgagctgg cgaaaaagcg
    10501 tctcccgcgc caggtgatga agcaattcgg ctatacggaa gaagagctgg agagccatac
    10561 cgtcaacaaa gcttttatga atgtatggga gtacatcgca tttgaggccg aggcgtattt
    10621 cgaggaggcg tctgaagagc tggagctgtt tccgttatac tcaaggcctg ccgttaccgg
    10681 tttgctggca cattaccggt cagagctcgg tgacatgaga aaacggcttt cgcaagcata
    10741 aaaaaaacgc ccggcttctt aacgaagctc cgggcgttta tgcaatccct ttttgaatcc
    10801 aaatccgcga ccgccatctt ctgtacataa gaatgcctct gacccattca tccgcgataa
    10861 atgaaatcca gatgcccata agccccaatc cgaaatggat gccgaacaga taagcgagag
    10921 gcagtccgat accccacatg gaaatcatcg ccatgtagac ggggaatttt gcatctccgg
    10981 cagcccgcag cgagttgatg ataatgacat taaatgaacg gccgggctca agaatgatcg
    11041 tcatggcgat cagcatgctc gccgtcgcaa taatgtcagg gctgcttgtg aaaattccga
    11101 tcagctgctt tgaaaacaag gtcatgatca cggatgtcaa agcggcaatg ccaagcgccc
    11161 agtacagact tttcatgcag cggtcataag cgtcgtcaaa ccgtttggcg ccgatatatc
    11221 tgccgatcaa aatctgtgtg ccctggctga tcgccgttcc gaacagcagg ataaacatgg
    11281 tgatgttttg tgtataaacc tttgttgtaa gcgcctgagc gcccataatg gcgataaaat
    11341 aagtgacaac catttgtgaa atgttgtaag acagctgttc accggcagac ggaatcccga
    11401 ttttcaggag tttccgcaag tgctctttat ggacgtgaaa aatcttttgc catgtcagac
    11461 cgagtccgat gcgttttttg acgatcacaa tcatcgcgat cagcccgatg atccgcgcaa
    11521 aggacgttga catcgcaaca ccggcgacgc ctaacaccgg aaggccgagc ggcccgaaaa
    11581 tgacaagaaa gtttccggca atatttaaaa tattcatccc gatcgtaacg aacatcgtat
    11641 ccttcgtatg accgtagctt tttaaaatgg cgctgaacgt cataatcaaa gcctgaatga
    11701 aggacagccc gccgaccacc tgcaaaaaga ctttggcatc cggcatcaat tcattggaaa
    11761 gacccatcac atgaagcagc ggaacggccg caaaaaatat ggcggcgctg atggcgagac
    11821 tgatgacaaa gttcgctcct attgatacat aagccacttc ctgcgcctct tttttctgtt
    11881 tagatcctaa aaactgtgaa atcacaattg tcgtacccgt tgcgataaag ctgaacatca
    11941 cgataattaa atttaaaatc tgattgctga cacccacggc cgccacactg ttgtcagagt
    12001 attggctaag cataagagtg tcggcgtttc ccataaacat atataatgaa acctcaataa
    12061 atatcggcca agtcagcgcg tataatgaga gtttgtgatc agaggattgt ttgaatgcag
    12121 cccgttttaa aatcgcttgt ttcatttctt ttaacccctt tcctgaaaaa atcaacgttt
    12181 aaaagtgtac ctccattttc ttataataaa aagggagaga aacgaaactt cttgcaaaaa
    12241 tccgacttaa aaaggagggc cggaaatatg tcctttctcg agttcacagt ccctccgttc
    12301 ccggtcttta tcgctgcggg agaaggagtg ttcaaaaaag gcgaaaccca tgtgagacgg
    12361 gtcttcccgg tgtttgatct gctgtatgtg aaagaaggcg tcctctacat tacagaagac
    12421 gaaaacgcct tttccgttga agcgggagaa tacattctgc tttctcccgg ccttgaacat
    12481 tacggaacaa aaggcagtga agaaacgaca tcctattcgt ggcttcattt tgaaggagcg
    12541 gattatgagg tgacggaaac caccgggaac aactggtcgg agctgaggcg aaaaaaaggg
    12601 agctttgaag agccgtcccg ctaccgcttg tccctgccgc aaaaagggaa ggtgagacgc
    12661 ccgcagttta tggccgggca attcagtgtg ctgacagatg aaagcgccga gaactccgac
    12721 ctgccgctaa gaaagcagat tctgtttgaa gagctgctgc tccatcttca gaaagaagcg
    12781 ttccaaatcc cgtccgcaaa ggaaagagtc gcatgggagg ccgcccggta cctgcaggag
    12841 cactatcagg agaaaacaac catcaaagcg ctctcttcgg cacttcatta caaccaagac
    12901 tacgtgaccc gctgcatgca gcaggtgctc ggcgtcacgc ccggccagta tacgaacaaa
    12961 gtcagaatga cggaggcgaa acgtcttttg tccgcaacca atgacaaaat ggggacgatc
    13021 gcggacgcca tcggcatgga agacccgact tatttttcca aactgtttaa acagattgaa
    13081 ggcatttcgc cgcttgaata ccgcaaattc gtaagccgga aaacggactg acctaatacc
    13141 agagaacaga agagggatcg gtaagcatga aaatgacaat ttacgacgtg gccgaaaaag
    13201 cgggcgtctc catctcgacc gtctcgcggg tcatcaacaa tacggggagg atcagtgaca
    13261 aaacccgccg gatggtgctc cgtgtcatgg aggagatgga ctatcatccg aatgttcacg
    13321 catccgcttt gacgggcaaa aagacgaata tgatcggcct gatcaccccg gacatttcaa
    13381 acccgttttt cggggaactg gtgaaaagca ttgaagacag cgccggtgta cttgggtttc
    13441 atatcattat ctgcagcacc gattatcagc ctgaaaaaga aacgaagtat ttttcgatgc
    13501 tgcggcagaa gcaggcggac ggcattatat tcgcgacggg acttgatcat gatgacagcg
    13561 tcacggcgct tgatgatatt gtgaaatcgg gcatcccgct tgcgatgatt acgcaggata
    13621 aaccgctcgc gccgatggac gtcgtcatta tcaatgactt tctcggcggc tatacggcgg
    13681 ctgagcatct catatcttta ggccatgaaa gaatcgcctg tatcgtcaga aacggttcga
    13741 ccacaggtga aagagacaga atcaaaggtt ttcaaaaagc gctgcgggaa gcggggatga
    13801 cactagatga atcgctgatc ataccgacgg aatattcgct ggaaagcgga aaacaggcag
    13861 cgggcgagct gtttgacaga gaccttccga ccgctgtttt cgcctttaat gatgtcttgt
    13921 catgtgcggc gatacaggcg gcgcgctccc ggggcattcg ggtgccggaa gacttgtccg
    13981 tcatcggctt tgacaatacc attctcgctg aaatgacggc accgccgctc acgacgattt
    14041 ctcagcccat ccgcgaaatg gggcggcgtg tcgttgaact tctcattgat gagattcaag
    14101 ggaagaaaaa aacaaaaagc aaaatcattt tatctccgga actcgtcatc aggcattcta
    14161 cggcaccggt aaaaacgcgc cctcagcgat aaggcgcgtt ttttttctgt gaaaaacatt
    14221 gtcaaacgaa cgaaaagcat tgtaaaatta aaacagcttt ggagaaagcg cttgcgcaaa
    14281 tactgcggat tacaagcaaa gaaagcaaac agcttgagtt ataaataaag cgctttcaaa
    14341 atgatgattt ctgtttaata agagaaaccg cttgcgccat tacggcatgc ggcctcaaga
    14401 aaaaaggagc ggtgatagat gacagatcaa gtcagatgtg cggtgctggg attaggacga
    14461 ttagggtatt ttcatgcgaa gcatttagcc ggcgaagtgc ggggagccga gcttgcggcc
    14521 gtctgtgacc cgatgaaggg gaaggcggaa gcgtgtgcga aagaattagg aatcgccaaa
    14581 tggacggaga gcccgtatga actgctggaa gatcacacga ttgacgccgt catcattgtc
    14641 acgccgacaa gcacacatgc ggaaatgatc atgaaggctg ctcaaaacgg caagcacatc
    14701 tttgttgaaa agccgctcac cctgagtctt gaggaatcga taaaagtcat gaaaaaaatc
    14761 gaagaaacgg acgtcatctg ccaggtcggt tttatgaggc ggtttgatcc ggcatacgcc
    14821 gacgcgaaaa gaagaatcga cgccggggaa atcggcagac ccatttatta taaaggattt
    14881 acaagagatc aaggcgcacc gcccgcggaa tttatcaaac atagcggagg gcttttcatt
    14941 gactgctcga ttcatgatta cgacatcgca agatatctca tgaatgctga ggttacgtcc
    15001 gtgagcgggc acgggagggt tttaaagcac ccgttcatgg aggagtgcgg cgatgtcgat
    15061 caggcattaa cgtatcttga gtttgattca ggcgcggccg gcgatgtgga ggcaagccga
    15121 aattctccgc acggccatga catccgcgcc gaaataatcg ggacggcggg aagcatttta
    15181 gtcggcacgc tgcggaacag ccatgtcacc attttaacgg agtcaggcag cagctacgaa
    15241 attattccgg attttcaagc ccgctttaaa gacgcttacc gtctggagct tgagcacttt
    15301 gccgaatgtg tgaaaaaagg ggaaacgccg attgtgacag acatcgatgc cgcgattaac
    15361 ttagaaatcg ggatcgccgc gacggaatct tttaaaaccg gaaggcctgt aaagcttacc
    15421 ccgggcgccc ccaactatgc cggattatga tagattcgaa gtgaaaaagc aaaggcacgg
    15481 gaggcctttg cttttttatg attcgtatga gaaaaaaatg tagtcagtcg gcacgccttt
    15541 atagcccatt tggtgaagca tcgcacttat attgccgcga tggtatgtgc cgtgattcac
    15601 aatatgccgg atcacatcgg catatgtcgt ccggagcgtt cccatgcgcg gatgagaaat
    15661 ggagatcggg ccttccatgt tctccaagtc tcttaaaaat tcgctgtatt ctttgtccag
    15721 ttcagtcatt ctatgttcaa ccgcctcaaa atctccgtca agcttttcaa attgatcaaa
    15781 ttgcgagacg atttgttcgt aagtttctcc gtaaagcacg tgaagccaaa tgtaatccgc
    15841 ccggtatata tgcacaagca cggcgttcac agtcggaaaa acactatcca gtttctgctg
    15901 taagcttgcc gcgggcaggg tcttcagatg ctgaataact tgctcatttg cccatctgtg
    15961 gtagtgatac agctttaaaa tgtctgacat tccaattccc cctcttcctt ccggtacatt
    16021 caacatgacc tggccgaatt ccttttatcg aaacaaaagc gccgcaaaat aaaaagcagc
    16081 accccacatc accaatgccg agcattgatt caggatgccg aggagccggc cgcctgtatc
    16141 cgccgtttgg acgagccgtc ccgcgaatgc cagtccggcg aaccataccc aggaaaccat
    16201 gatacaagca ccggcaaaca gccatttatc aattcccgga taggcggcgg agcttgtgcc
    16261 gatgacactg acagtatcca aaatcgcatg cgggttcaaa agggatacca tggcggccgt
    16321 gaccgcctgt ttttttgccg tgaaaactgt ttttttcgcc tgttcggcct gcggtttgct
    16381 tctccaagtc tgccagccta aaaaactgag aaacaaaaag ccgcctataa gcatgacggt
    16441 ctgaaaaacg ggaatctctg caataatcat tgacacgcct gcgacggccg cgctgatgag
    16501 aatcgtatcg cataccgccg cggcaatcac tgcgggaaac gcctgccaca catgtttttg
    16561 ccaggctccc tgctgaaaaa taaacacgtt ttgcgcgccc aatggcaaaa taaggccgaa
    16621 agcgagcatc actccgtgaa gaatggcatt catatcgtaa aaccctccaa tcgtcaacta
    16681 catctcattg tagccgcact gtgtgctgat gtctccggcc atttggctgg tacttgaacc
    16741 agccaaatgt ataataaata aagaaggagg gatgacgtat gaacagctgg cgtccggatc
    16801 gggagtcgca cataccgctt tatctccaga tcgaacagca tataaaagaa aaaatacttc
    16861 atggcgaatg gaccattggc acgaaaattc cctcacaaag aaagctcgcc gaggagcttc
    16921 aggtcaaccg aagcacagtg acggcagcag ttgatgagtt aatcgcccaa ggtcttctgg
    16981 aaggaaaaag agggggaggc acaaaggtcg tcaacaatac gtggagcatc atggcagcgg
    17041 ctaagcccct tgattggagc acgtacgtta catcggggag tcatcagccg aattcaccct
    17101 tgattcaggc cattaatcaa aacgagccgc gtccggatct gatcaggctg gggacgggtg
    17161 agctgagtca agagctgctg cctgagcagg agatgggcga actgttccgt gaagcgggaa
    17221 ctaacatttt tgcgctcggc tatgaagaac cgaagggcag cctgcagctt cggcaaagcg
    17281 tcgcggaaca tttgaaaaca aaggggattc acgcgtcccc ggcatccatc gtaatcgtct
    17341 caggcgcgct gcaggcgctt cagctcattt caatcgggct gctaaaacca aactccgtca
    17401 tgctgactga aaacccgtcg tatctccatt ccctgcgtgt gtttcaatca gcgggcgtca
    17461 agcttaaggg agtgccgatg gatgagagcg gaatcaaaac ggatcatctt cccgattacc
    17521 ggcggcaata cgaagcgggg ctgctgtaca ccattccgtc attccataat ccgaccggaa
    17581 cggtaatgtc actcaagcgg cggaaggaac tcatcacgct tgcaagaaat caccgtctgc
    17641 ctgtcattga agatgacgca tacggtgata tatggatcga taaagaaccg ccgcctccgt
    17701 taaaatccat ggacggtgag gggaatgtac tgtatatcgg cacgctgtca aaaaccgtaa
    17761 gcccgggtct gcgcatcgga tgggtcgtcg cccctgagcc ggttgcagac aggctcgccg
    17821 atattaaaat gcagacggat tacggctcca gcgctttatc tcaatgggcg gcatgtcaat
    17881 ggctgtcaag cggccgctat gaagcgcgtc ttttgcgtct cagaaaggaa ctcaaaatca
    17941 ggagagatgc ggcattgtgt tttcttgaaa gatacgcggg agatattgcg gagtggcggg
    18001 tgccggaggg gggcttttat atttgggtca cctttcataa agcattcgcc gttcagacgc
    18061 ttttcacccg tgccttggag tccggcgtgc tgatcaatcc gggagctctc tatcttcccg
    18121 aagaccggca aagcctgcgt ctttcctatt cgtacgcatc tttaccggac ttggaaaaag
    18181 gcattcaaac gatagcggat attgcccgcc gtttcgttta ataaaagatc acgtcacaat
    18241 ggcgccgagc gcttctgcga atgtagcggc atgcgccgga gagatgcggc atcctttcag
    18301 cttatcaagc gagacatgca gatgatcaaa tgtgcacgtg ctgatatcca tattaaaaag
    18361 agacgtgccg atgaagtttg cgccgttcaa atcacagacg tcaagatctg tgtattcaag
    18421 aacggaatca ttccactcac tttctgaaag gccgcacgag tcaaaacgga catgcttcat
    18481 attggaatag ctgaaggagc tgtaatttgc gaggcagtct tcaaaccgta catgacgcat
    18541 ggcggaatcc gccagattca agccgagaag ttttgaatgc tgaaacgccg ttctatggat
    18601 gatgctttcg ctgaaatcag cgtttgagac atcgcatttg tcaaacagga catccgtaca
    18661 ttccatatgt ctgaaagaga tatccgtgaa aacgatgttt ctgaaaataa ctttttcggc
    18721 acgcaggccg tccagtttgc cgtttacgat gccgttttca atgatgactt ctttgagctc
    18781 ctcatcctga agcgcttcag tgaaagaaag caccggcaat tctttcggga ttttcggttt
    18841 ttggatcgta ttcatctcat actccctttt ctaaacataa tagctgaaat cggcaattgg
    18901 cagatatcgc tttctgcctg ccatccttgc tgttgcgtaa tgtacaaagg gtattaaaaa
    18961 agcgggaggg cgtcaatagt gtcgcatata aaagcagacg tgacattcaa ggtaataccc
    19021 ttagagacat gtccccaagg gcttttgcct gtttcaggcg agttctttat acatgatcac
    19081 atgtgggccg atgccgggta tgtcaaaggg gctgcccgtg cttttccagc cgagcttttc
    19141 gtaatatccc ttcacgtgac atctggcgtt gcaccagaca agcgccgccc ccatatctgc
    19201 cagttttcgt tccgcatagg cgattaacgt gcttcccgct ttttgcgtcc ggtattcttc
    19261 aagcgttgcc atgccgcgca gctgataggc gggcgccgcc tgtaaagcct gctggttctg
    19321 cgggtagaaa gaagcgatgc tgatcaatgt cccgtcgtaa aaaccgccga gatgaaatgc
    19381 tccttcgacg ctgtcctgat catatttaca atcctcaatc gtctgatggg ggcgcagcac
    19441 gctgtgtctg atcgcgtatg tgtcttctgc ggtgatgggt tttacttcaa ccataaaaaa
    19501 atcctccttt gcttgattct ttttctgtat cgtaccatga aaaagccgcc tgtcatatca
    19561 ggcggcctct tccgcgtcaa tgcaaatata catcagcccg cttttcatcc ttttgcttaa
    19621 tataagctgc aagttctgat gtcaaatcag aacggagaaa cggggtgatt aaataaattc
    19681 cgttaaacag ttcgcacgcc gtgtcgagaa gcgacttggc gatggcgagg ccttcggctt
    19741 tctgcttttg cttgtcttcg ccggcgagcg ccattttttc ccggatgctg tctgacagct
    19801 taatgcccgg gatttcatga tgaatgaact ctgcgttgcg gctgctcgtt aacggcataa
    19861 ttccgatata caccggtgtt ttgagatgtt tcgtttcatg atgaatgtca atgagctgct
    19921 gctcggagta gacaggctgg gacacgaagt agtcagctcc gcactcgatt tttttctcca
    19981 gccgttttac tgctttatca agatggcgga cattcggatt aaatgctccg gctacggaaa
    20041 agttcgtttt cttgccgagc ggtttccctg ataaagaaat gccctcgttg aattgcttaa
    20101 tcagcctgat caagtcaaag gacgttaaat catagacgga ggtagccccc ggaaagtcgc
    20161 cgatttttga aggatcaccc gtgatggcta aaatgtcggt aagcccgagc gtatccagcc
    20221 ccattaaatg tgactgaagg ccgatgatgt tgcggtctct gcatgtaatg tgaacgagag
    20281 aacggatatc aaggcgctct ttcagcaatg aaccgcaggc ggcattgctg atccgcggtg
    20341 tcgccaatga attgtcggcg agcgtcagcg cttctatgcc ggtttctttt aattcagccg
    20401 ccgcttgcag aaatttgtca aaattcaatt ttttcggcgg atcaagctct acgataattg
    20461 accgtttttg agcggcgatt tcgtttaaac caggctcggt ccgttcattc cggacggaga
    20521 tgacttcttc ttcccgtctg attttcactt ctttatcagt gacgggagaa agtccgcgga
    20581 ccgcttcagc catggctctg atatggtttg gcgtcgtacc gcagcagccg ccgataatgc
    20641 gcgcgccctg agtgcggaac tgtacggcgc tctcccggaa ataggcatcg tccgtatcat
    20701 aaacaagccg gccttcttct aaagacggaa ggctgctgtt c
//
