LOCUS       NZ_CP021011            26360 bp    DNA     circular CON 17-JAN-2024
DEFINITION  Bacillus velezensis strain GFP-2 chromosome, complete genome.
ACCESSION   NZ_CP021011
VERSION     NZ_CP021011.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 3975220)
  AUTHORS   Sun,C.
  TITLE     Complete genome sequence of Bacillus sp. GFP-2, an antibacterium
            strain isolated from shark gut
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3975220)
  AUTHORS   Sun,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2017) College of Life Science, Zhejiang
            University, 866 YuHangTang Road, HangZhou 310058, China
COMMENT     ##MIGS-Data-START##
            alt_elev                          :: not reported
            assembly                          :: not reported
            collection_date                   :: 01-Oct-2016
            country                           :: China
            depth                             :: Not reported
            environment                       :: Shark intestine
            investigation_type                :: bacteria_archaea
            isol_growth_condt                 :: 10-40degC; 1% NaCl; ph 7
            lat_lon                           :: not reported
            project_name :: Genome sequence of Bacillus sp. GFP-2
            sequencing_meth                   :: A pacbio RS II platform
            num_replicons                     :: 1
            Estimated size                    :: "3,975,220 bp"
            ref_biomaterial                   :: GFP-2 = CGMCC 13337
            trophic_level                     :: Chemoorganotroph
            rel_to_oxygen                     :: Aerobic
            Library reads sequenced :: The large smrtbell gdna protocol (Pacific
            Biosciences, USA)
            Assembly method :: De novo assembled using the PacBio hierarchical
            genome assembly process (HGAP)/Quiver software
            Estimated error rate :: 99.99 % (average reference consensus)
            Method of calculation :: Estimation from HGAP Assembly quality
            scores
            Assembly name :: HGAP Assembly version 2 (Pacific Biosciences, USA)
            finishing_strategy                :: not reported
            biotic_relationship               :: free-living
            ##MIGS-Data-END##
            ##Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Coverage                          :: 247.76
            Sequencing Technology             :: PacBio
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 08:46:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,936
            CDSs (total)                      :: 3,818
            Genes (coding)                    :: 3,738
            CDSs (with protein)               :: 3,738
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 80
            CDSs (without protein)            :: 80
            Pseudo Genes (ambiguous residues) :: 0 of 80
            Pseudo Genes (frameshifted)       :: 52 of 80
            Pseudo Genes (incomplete)         :: 49 of 80
            Pseudo Genes (internal stop)      :: 17 of 80
            Pseudo Genes (multiple problems)  :: 31 of 80
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:25:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1216586
            Orig. end                         :: 1242946
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26360
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26360
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26360
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16360](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16360)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(101..1240)
                     /gene="opuCA"
                     /locus_tag="B6257_RS06425"
                     /old_locus_tag="B6257_06390"
     CDS             complement(101..1240)
                     /codon_start=1
                     /gene="opuCA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013353644.1"
                     /locus_tag="B6257_RS06425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06390"
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OpuCA"
                     /protein_id="WP_062623563.1"
                     /transl_table=11
                     /translation="MLRLENVSKVYKGGKKAVSSIDLNIEKGEFICFIGPSGCGKTTTM
                     KMINRLIEPSSGKIFIDGENIMEQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPKLL
                     KWPEQKRKERARELLKLVDMGPEYLDRYPHELSGGQQQRIGVLRALAAEPPLILMDEPF
                     GALDPITRDSLQEEFKKLQRTLNKTIVFVTHDMDEAIKLADRIVILKAGEIVQAGTPDD
                     ILRNPANEFVEEFIGKERLLQSRPDIERVEQMMNKKPVTVTADKTLSQAIQVMREHRVD
                     SLLVVDDLNVLQGYVDVEIIDQNRKKASLVGDVLRSDLYTVEQGTLLRDTVRKILKRGM
                     KYVPVVDEQRHLVGIVTRASLVDIVYDSIWGEEDQLVTG"
     misc_feature    1267..1281
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.56"
                     /tool="antismash"
     CDS             1329..1475
                     /gene="allorf_1217915_1218061"
                     /locus_tag="allorf_1217915_1218061"
                     /protein_id="allorf_1217915_1218061"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKLYTIYVFFHVIPLTMRMFLQSLPIARISCRIIFFINCKKYDI
                     LSA"
     CDS_motif       1329..1412
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /locus_tag="allorf_1217915_1218061_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1413..1475
                     /prepeptide="core"
                     /locus_tag="allorf_1217915_1218061_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2367.9"
                     /monoisotopic_mass="2366.3"
                     /core_sequence="RISCRIIFFINCKKYDILSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKLYTIYVFFHVIPLTMRMFLQSLPIA"
                     /leader_location="[1328:1412](+)"
     misc_feature    1335..1353
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.41"
                     /tool="antismash"
     CDS             complement(1361..1444)
                     /gene="allorf_1217947_1218030"
                     /locus_tag="allorf_1217947_1218030"
                     /protein_id="allorf_1217947_1218030"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMKKMMRQDMRAIGSDCKNIRIVSGIT"
     CDS_motif       complement(1400..1444)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMKKMMRQDMRAIGS"
                     /locus_tag="allorf_1217947_1218030_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1361..1399)
                     /prepeptide="core"
                     /locus_tag="allorf_1217947_1218030_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1282.5"
                     /monoisotopic_mass="1281.7"
                     /core_sequence="DCKNIRIVSGIT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMKKMMRQDMRAIGS"
                     /leader_location="[1399:1444](-)"
                     /alternative_weights="1300.5"
     gene            1501..2058
                     /locus_tag="B6257_RS06430"
                     /old_locus_tag="B6257_06395"
     CDS             1501..2058
                     /codon_start=1
                     /function="Predicted transcriptional regulators"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391264.1"
                     /locus_tag="B6257_RS06430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06395"
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_014418904.1"
                     /transl_table=11
                     /translation="MEKNALDIIGHAEEHLIERIAENMHTFGMPATLGRVLGIIYMNRK
                     PMTLNELSEATGMSKTRMSQVVREMTDANLAEKVFEKGVRKDLYDVERDYYQTFISLFT
                     ANWTKAVSKNKMLYKKLNRELTELLESENLSPDIEEKARQLLDELTDWLHYYDWLSRLI
                     EFFESEEVFQHVPKIEKSSTRR"
     gene            complement(2079..2711)
                     /locus_tag="B6257_RS06435"
                     /old_locus_tag="B6257_06400"
     CDS             complement(2079..2711)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471043.1"
                     /locus_tag="B6257_RS06435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06400"
                     /product="NAAT family transporter"
                     /protein_id="WP_071392294.1"
                     /transl_table=11
                     /translation="MFSFIIHVFISLFAVSNPIGNVPIFLSLTEGYPEKERTAIARKAS
                     VLSFIILAAFLIFGHLIFKLFDINIHALRIAGGIFIFGIAYNLLNAKQSHVQSLHHEEK
                     GESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHGGIIHYISVLIGIAAVIAMTFIFF
                     HYSSFISNKLGKTEMNVITRLMGLILAVVAIGMIGAGLKGMFPILVS"
     gene            3151..3861
                     /locus_tag="B6257_RS06440"
                     /old_locus_tag="B6257_06405"
     CDS             3151..3861
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007409971.1"
                     /locus_tag="B6257_RS06440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06405"
                     /product="hypothetical protein"
                     /protein_id="WP_022553805.1"
                     /transl_table=11
                     /translation="MYCSQCGHHTDGGKFCEKCGAPQPGQGGAGQTQGQAAQAGAAAKQ
                     ASKQFALFVLDVLKRPYQTCKTTGGEQLVSSIINMVLFCLVTPIMFYILLSDGFRDVSF
                     TAVVIKPALTFALCVFCLYLLIFIALKAGGAQVSFKDSLSRFGAFLIPFTAILLLALIF
                     MLLHTTVCFTILAVGLLGAAFAVPPLMLASYQHQLTAKADIIYSVIVIYLIICVTFQFT
                     IKHYIKELMNYFFF"
     gene            complement(3900..5690)
                     /locus_tag="B6257_RS06445"
                     /old_locus_tag="B6257_06410"
     CDS             complement(3900..5690)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305844.1"
                     /locus_tag="B6257_RS06445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06410"
                     /product="hypothetical protein"
                     /protein_id="WP_071392295.1"
                     /transl_table=11
                     /translation="MFFCKYCGRQNNEEAHFCKECGKPIGKGSRLERQAAVRAAEPASQ
                     MRKPIPKKTLFIWGGIAAALILLIAAYKTGAWLTSEKRLTDQFEQAVHDGDTKKLAALL
                     TPSDKKLKLNETNVKPLLAYAKKHDELLATLRGNSSEKDAVYVKKEGKTLLLFDHYELK
                     VDPVYFRVTSNYKGADLYINSEKTGTVKKADETQIFGPYAPGVYTAEAKLKNDTVDVVK
                     KQEAEAAGSRNVDFDLPLDAEDVTFTPADSFKSAKGDLLINGKSVHKDPFKSVTYGPLL
                     TDGSMTAAVEADFPWGKMKTADVPINGTDMELTLIPDQDTQQTIMDTIVNTTKQYTKAM
                     ADGNTDQMTEAGYAWKEQTKEVVSGMKSSGTFLKDQYKETSFDLDSFAISQENGRWQAT
                     VTGKELHESAYFDGNTKPDMEEAEPSFHYVLSYDTKHKKWVFEKADPASDSSGTNVKKI
                     KNDQPKTYTSAWASSKGNTASGSVTNEQVTSFMTDYLTNQSSAVSLNNFAIMAGNLEEG
                     SPLYADQQKLVKKLHSEGTTEVFNEVNVKSFSQKGSHLTIHTYEEFYITKAGGSPKLRT
                     YNWTYGGVVKDGRIYLTSIQ"
     misc_feature    complement(5774..5787)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.2"
                     /tool="antismash"
     gene            5822..6283
                     /locus_tag="B6257_RS06450"
                     /old_locus_tag="B6257_06415"
     CDS             5822..6283
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151638.1"
                     /locus_tag="B6257_RS06450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06415"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_101562438.1"
                     /transl_table=11
                     /translation="MQKLSIRKAAEPDEALYELLLLADPSKEIVDDYLVRGECYTAWTS
                     DELAGVYVLLQTRPKTIEIVNIAVKESLQNRGFGKQLVRDAIEKARETGTDTIEIGTGN
                     SSIHQLSLYQKCGFRIQAVDHDFFIRHYDEDIFENGIQCRDMIRLYLDL"
     gene            complement(6344..7353)
                     /locus_tag="B6257_RS06455"
                     /old_locus_tag="B6257_06420"
                     /pseudo=""
     CDS             complement(6344..7353)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="B6257_RS06455"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="B6257_06420"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRLGGVFYGIRVSDPVEVKQEV"
     misc_feature    complement(7544..7557)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.22"
                     /tool="antismash"
     gene            complement(7641..7811)
                     /locus_tag="B6257_RS19850"
     CDS             complement(7641..7811)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B6257_RS19850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_154303051.1"
                     /transl_table=11
                     /translation="MKNYKGDGAVFLVIGFCLGLFLGVVFDILPYGLSIGILIGSLIDL
                     YFYARHKNNNK"
     gene            complement(7848..10004)
                     /locus_tag="B6257_RS06460"
                     /old_locus_tag="B6257_06425"
     CDS             complement(7848..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="B6257_RS06460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06425"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_057080225.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.6e-37, bitscore:
                     125.0, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKKKKRVPIVKQLQQTECGLCCCAMLIRFYNSNETLFELRSFL
                     EAGRDGLTIKQLKNLLVHKGFKADIYKSTILGLKKINVPFIAYWNNEHFIVVEKIKENY
                     YYIIDPANGRRKLTEEEFKKGFSSYILYAVPSESFTPNKRKDKNVWFGVLKNITNYKLL
                     FSIIVFLSLISYLLTLYVPILVQKLIDTSIEYNNLNSISNIVWITFLISILYGMFVLFR
                     GLKMISLNIFLSKNLVVDTFAHLLKLPFKFFDLRSPGDLLFRLNSMNGFRELLSTQLIS
                     GLIDLGAVVFILAYMFFKSIPLTLITILIFAINTVFMFLTRPAVAQAIDDEVAEQSKSQ
                     AIQIESIFSIAAIKISGMENEIFSTWNNSFNEVIKRFKKRSILQNVVNTVTQVFQTIAP
                     LVILILELLLFFDNKFTMGEVIAYHSLSVTFFGLTTSLFGTYTQFILATSYLERVKDIT
                     ETECEKNIENAVNLKLRGNVKLENVSFSYTKHSPKVLKNISLEIREGQKIAIVGSSGSG
                     KSTLSKLIMGLYDPTEGQICFDSIPLEKLDRKQLYKQMGIVPQDITLFNSSILKNITLN
                     NKNISVEKVRKVAKAAQIDKEIESMPMKYNTPISEMGMNLSGGQRQRIVLARALLNDPK
                     ILILDEATSSLDLVNESLISKYLSEMGCTRVVIAHRLSTIIDSDFIIVLDKGEVVESGK
                     HEDLIALEGVYSNLYRSQTKKEKT"
     gene            complement(10001..12940)
                     /locus_tag="B6257_RS06465"
                     /old_locus_tag="B6257_06430"
     CDS             complement(10001..12940)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="B6257_RS06465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06430"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_101562439.1"
                     /sec_met_domain="DUF4135 (E-value: 5.5e-88, bitscore:
                     293.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-61, bitscore:
                     206.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISYENNNFITDAVINFSSPTNEVEKLRIKNKDYFGNFYTFFLD
                     FYQQRLVNTLENASKENNVKLNKHKIISSALEAFNQELIQLCIRTLIVDINERKEKGLL
                     EGKDSRSRYKNYNNLIFKSEYVAEILNKYPVLTYLISSRISNKILYLKEVLENLRKNRQ
                     DIYRELKIEFDEVSNIYFSSGDTHNGGKNVLIIETNQGKIVYKPHSLSPDILFNSIVDY
                     VNNSDKILKKIYKTRTLNYKDYGYQEFIDYKECETSEKLNFYFYRVGVSLSIFHIIGCD
                     DLHHENLIAHGEYPVVIDLETLIKNNSMYKPRNNNLIDNFHEDINYSVLGTMLLPLNLQ
                     TSIFDFDLGGISNDENQTSEIWKSYIIDFEGTDEIQLTKKSVIMNSTQNRAAYNGKAAD
                     PKDYIEEILKGFTDCYNFVLENKSGFYDLVKKVGNSNLEVRQVLRATSIYARFLEASTH
                     PNYLSSFEDRKELFKKINIAEGVTDKFSKKNLNELESLMCNDIPYFSTMYNSLDLICNK
                     STSIVNFFRECLLDVVLNKIKSISKTSLKKQQYYIRMSLTTTIKDSWKRTNKHNKKYRP
                     KLFGNNYKNYLECATEIGDLFLETAIWNNDRSKCTWVTPIISENNKVKLGPLNFDLYEG
                     GGVILFLALLGKETGNKEYFDLAFAGMRGIEELFLSDDKMDGRLSLFTGIGSLSYIYYH
                     LYTYTNDYKYYEKFKKYINKINEMNISGDIPLDIVGGVSSLIVFLLNLYKETKLDILNS
                     VCCKLGNTLYQCLEKNGKHNYLTGLSHGYSGFTWALCYLGHITKDEKYTTLGKELLKRE
                     NKFFDLNTSNWKDLREGEGNSDPVYWCHGAGGIALSRAFLKNLLKNKENVVDKEFDKDL
                     NCAISKLLSDGFKKTTDHSLCHGIFGNIDILLKLSELLNDIDLQEVAFKEAQNAINYIR
                     NKGFIPGLQDHFDLNTFMLGLGGVGYSLLRLHNPVNPSLLAMEVRSYNE"
     gene            complement(13018..13224)
                     /locus_tag="B6257_RS06470"
                     /old_locus_tag="B6257_06435"
     CDS             complement(13018..13224)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="B6257_RS06470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06435"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_025854095.1"
                     /transl_table=11
                     /translation="MKKDMVKKASGFIEEDELISLANGDNATGGATPTVVLTATIGLTG
                     TTFTVTLSAASCPTSACTKQCNK"
     CDS_motif       complement(13135..13224)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /locus_tag="B6257_RS06470_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13018..13134)
                     /prepeptide="core"
                     /locus_tag="B6257_RS06470_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="3508.0"
                     /monoisotopic_mass="3505.9"
                     /core_sequence="ATPTVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDMVKKASGFIEEDELISLANGDNATGG"
                     /leader_location="[13134:13224](-)"
                     /alternative_weights="3526.1"
                     /alternative_weights="3544.1"
                     /alternative_weights="3562.1"
                     /alternative_weights="3580.1"
                     /alternative_weights="3598.1"
                     /alternative_weights="3616.2"
                     /alternative_weights="3634.2"
                     /alternative_weights="3652.2"
                     /alternative_weights="3670.2"
                     /alternative_weights="3688.2"
                     /alternative_weights="3706.3"
     gene            complement(13274..16360)
                     /locus_tag="B6257_RS06475"
                     /old_locus_tag="B6257_06440"
     CDS             complement(13274..16360)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="B6257_RS06475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06440"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_101562440.1"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-97, bitscore:
                     325.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.6e-66, bitscore:
                     221.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNKYNLQYWMKMFPEVNNKDELQKIFLNVSGKTIQSLIRDDTN
                     IEQNTNIIDIDRVLDHKKSDFLVRNSEEFLEHNPFFHFFSPFLNCKIEEFIVKVRIEDA
                     VDNEDEFVKKVIKHIVDLMFEKAFRVLVLEVNIARLEGNLEGTTPQERLNHFLVVSLND
                     ESFLKSVYKEYEVLTSLLCVTIDDYFTYVMEIIKNTKREISSLNSKFNSDNDLGAITNI
                     TTGLGDTHQKGKSVSTIYFKSGKKIIYKPRDLRLEQGFQEVLYWLGGKNIPGILNFKRV
                     QIHTVNDSGWMEHIDYKSCFNKKEANDFYTRSGNLLCLLYLLNSVDFHHENLIAHGSFP
                     VLVDLESLFHARLKVDQIDKKSAVVKATELVDNSVQSISLLPTKISKRVGDKDISLDIG
                     GLGAHKEQLSPHKSLVIENAGTDTIKILRKNTFIKPQLNNPSIKTGSYLYSENYTGQIK
                     DGFASLYSWVMLNKDEFWNKISQTFKETNSRFIFRPTYLYTQLLRISSHPDFMRDTYRR
                     KIILHRIGIDYIQEYKDILNSEYKDLLTGDVPFFTSSIEHENLIDSRGEKIHSILEEPP
                     IKTVKQKIFNLSKEDLKRQIDFIEMSYISNEKRLKEVTDIKFSKAANLNKIKSENWIDE
                     ATQIGEFIVDNSVCGINKKQKDRMWIGPSLEGIEEDIWNANVLGFDIYNGNSGIALFLG
                     YLGEILNRKDFKQAAIETMRPIQKFISEIKEDHPYLIGAFQGISGYFYTLNKLSNLFED
                     SELKGASLENISVLSKLGKFDKVYDLIGGSLGSLAVTLSIIPDITEENSKKEILKISHT
                     HCDHILSVAKNFEEQISWPGKFSAAYSGFSHGNSGFIAYLYKYFKLTNDEKLLEVIQKA
                     LRFERRLYSEDHNNWYTTENKDKLANGWCHGAPGILLSKLILKDNGFEDEYIEKEISTA
                     IDSSIRNGIGNNPTYCHGDLGVLSILNYASDLTNNINLKNRCLRTYQDLFENVLTKKWR
                     KRDLVCTRSYSLMIGLSGIGYSMIKNYAPEIVPNFLWLE"
     gene            complement(16432..16662)
                     /locus_tag="B6257_RS06480"
                     /old_locus_tag="B6257_06445"
     CDS             complement(16432..16662)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884148.1"
                     /locus_tag="B6257_RS06480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06445"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_021495220.1"
                     /sec_met_domain="mature_ha (E-value: 4.9e-07, bitscore:
                     27.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGAFNTWNT
                     TTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
     CDS_motif       complement(16546..16662)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /locus_tag="B6257_RS06480_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16432..16545)
                     /prepeptide="core"
                     /locus_tag="B6257_RS06480_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3669.1"
                     /monoisotopic_mass="3666.9"
                     /core_sequence="FNTWNTTTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /leader_location="[16545:16662](-)"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
                     /alternative_weights="3777.2"
                     /alternative_weights="3795.3"
     misc_feature    16849..16863
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.81"
                     /tool="antismash"
     gene            complement(17980..19272)
                     /gene="eno"
                     /locus_tag="B6257_RS06485"
                     /old_locus_tag="B6257_06450"
     CDS             complement(17980..19272)
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391270.1"
                     /locus_tag="B6257_RS06485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06450"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_007409956.1"
                     /transl_table=11
                     /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGE
                     YEAVELRDGDKDRYLGKGVLTAVNNVNEIISPELLGFDVTEQNAIDQLLIELDGTENKG
                     KLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ
                     EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGMNTAVGDEGGFAPNLGSNEEALQTI
                     VEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEEMVSKY
                     PIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIKNGVGNSILIKV
                     NQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDR
                     VAKYNQLLRIEDQLAETAQYHGINSFYNLNK"
     gene            complement(19300..20835)
                     /gene="gpmI"
                     /locus_tag="B6257_RS06490"
                     /old_locus_tag="B6257_06455"
     CDS             complement(19300..20835)
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene="gpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391271.1"
                     /locus_tag="B6257_RS06490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06455"
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="WP_101562441.1"
                     /transl_table=11
                     /translation="MSKKPAALIILDGFGLRNETVGNAVAQAKKPNFDRYWNQYPHQTL
                     TASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIKNA
                     KDNDKALHLFGLLSDGGVHSHINHLFALLKLAKSEGLTKVYIHGFLDGRDVGPQTAKTY
                     IQQLNEQIEETGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSAMDVVDD
                     SYANGIHDEFVIPSVITKENGEPVAKIHDGDSVIFYNFRPDRAIQISNTFTNKDFRDFD
                     RGENHPKNLYFVCLTHFSESVDGYVAFKPVNLDNTVGEVLAQHGLKQLRIAETEKYPHV
                     TFFMSGGREEEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIAADKHDAIILNF
                     ANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAIIAKGGHAIITADHGNADILITETGEP
                     HTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK"
     gene            complement(20828..21589)
                     /gene="tpiA"
                     /locus_tag="B6257_RS06495"
                     /old_locus_tag="B6257_06460"
     CDS             complement(20828..21589)
                     /EC_number="5.3.1.1"
                     /GO_function="GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391272.1"
                     /locus_tag="B6257_RS06495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06460"
                     /product="triose-phosphate isomerase"
                     /protein_id="WP_003151618.1"
                     /transl_table=11
                     /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPAL
                     FLEKLTSAVKGTDLKVGAQNMHFEENGAFTGEISPVALKDLGVDYCVIGHSERREMFAE
                     TDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVAASV
                     IAYEPIWAIGTGKSSTAKDANDVCAHIRKVVAESFSQETADKLRIQYGGSVKPANIKEY
                     MAESDIDGALVGGASLEPQSFVQLLEEGQYE"
     gene            complement(21615..22799)
                     /locus_tag="B6257_RS06500"
                     /old_locus_tag="B6257_06465"
     CDS             complement(21615..22799)
                     /EC_number="2.7.2.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391273.1"
                     /locus_tag="B6257_RS06500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06465"
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_003151616.1"
                     /transl_table=11
                     /translation="MNKKTVKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIK
                     HLADQGAKVLLASHLGRPKGEVVEELRLTPVAARLGELLGKEVKKADEAYGDAVKAQIS
                     DMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIAEHL
                     PAVAGFLMEKELDVLGKAVTNPERPFTAIIGGAKVKDKIGVIESLLDKVDNLIIGGGLA
                     YTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVKFYMPEDVLVADDFSNDANVQIV
                     PISEIPSDLEAIDIGTKTRETYAEVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAE
                     ANDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALNDK"
     CDS             complement(22864..23094)
                     /gene="allorf_1239450_1239680"
                     /locus_tag="allorf_1239450_1239680"
                     /protein_id="allorf_1239450_1239680"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGLLQNVRVLKFP
                     RHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
     CDS_motif       complement(22990..23094)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /locus_tag="allorf_1239450_1239680_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22864..22989)
                     /prepeptide="core"
                     /locus_tag="allorf_1239450_1239680_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="4707.5"
                     /monoisotopic_mass="4704.6"
                     /core_sequence="LQNVRVLKFPRHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /leader_location="[22989:23094](-)"
                     /alternative_weights="4725.5"
     misc_feature    complement(23042..23051)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.98"
                     /tool="antismash"
     gene            complement(23121..24128)
                     /gene="gap"
                     /locus_tag="B6257_RS06510"
                     /old_locus_tag="B6257_06475"
     CDS             complement(23121..24128)
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391274.1"
                     /locus_tag="B6257_RS06510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06475"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_003151611.1"
                     /transl_table=11
                     /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLL
                     QYDSVHGKLDAEVKVDGSNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTKRA
                     DAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFAKV
                     LNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSLVLPE
                     LKGKLNGGAMRVPTPNVSLVDLVAELNKDVTAEDVNAALKEAAEGDLKGILGYSEEPLV
                     SGDYNGNANSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKQGL"
     gene            complement(24162..25196)
                     /gene="cggR"
                     /locus_tag="B6257_RS06515"
                     /old_locus_tag="B6257_06480"
     CDS             complement(24162..25196)
                     /codon_start=1
                     /gene="cggR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151607.1"
                     /locus_tag="B6257_RS06515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="B6257_06480"
                     /product="gapA transcriptional regulator CggR"
                     /protein_id="WP_003151607.1"
                     /transl_table=11
                     /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLAASLG
                     LTERVLRSEVQFLKEQNLIDIKTNGMTMTEEGYSLLSILEDTMKDVLGLTLLEKTLKER
                     LNLKDAIIVSGDSDQSPWVKKELGRAAVACMKKRFSGKNIVAVTGGTTIEAVADMMTPD
                     SKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEP
                     SVKEVLHTIKSASMLVHGIGEARTMAERRNTPLEDLKKIDDNHAVTEAFGYYFNADGEV
                     VHKVHSVGMQLDDLDAIPDIIAVAGGSSKAEAIEAYFKKQRNTVLVTDEGAAKKLLRDN
                     SPSI"
     misc_feature    25292..25305
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.01"
                     /tool="antismash"
     misc_feature    complement(25384..25402)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    complement(25512..25526)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(25806..25822)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    26275..26290
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
ORIGIN
        1 atcgaaatgt ataaatgctc ccacgtttta tataacagtt ctccgccgtt cgtctgcaaa
       61 aacttgatca tttcattcat tgtaagcgtt cctccccttg tcagcctgtc accagctggt
      121 cttcctcgcc ccagattgaa tcgtaaacga tgtcgacaag gctcgcccgc gtgacaattc
      181 cgactaaatg cctttgttca tcaacgacgg gtacatattt cattccgcgc tttaaaattt
      241 tgcgtacggt atcacgcagc agtgtaccct gctcgaccgt atacagatca gagcggagca
      301 cgtcgccgac gaggctcgct tttttccggt tctgatcaat gatctcgaca tcgacatacc
      361 cttgcagcac attcaggtca tcaacgacaa gcagggaatc gacacggtgc tcccgcatca
      421 cctggatcgc ctgcgaaagc gttttgtccg ccgtaacggt gacaggcttt ttgttcatca
      481 tctgctcgac gcgctcaatg tccggtcttg attgcaataa ccgttctttg ccgataaatt
      541 cttcgacaaa ctcattagcc ggattccgga gaatgtcatc aggagtgccg gcctgaacga
      601 tctctcccgc ttttaaaatg acgatccggt cagccagctt aatggcttca tccatatcgt
      661 gggttacaaa cacaatcgtt ttattcaatg ttctttgcag ttttttgaat tcttcctgaa
      721 gggaatcccg tgtaatcggg tcaagcgcgc cgaacggttc atccataaga ataagaggcg
      781 gttccgctgc aagggcgcgc agcacgccga ttctctgctg ctgtcccccg ctcagctcgt
      841 gaggatagcg gtctaaatat tccgggccca tatcgacgag cttcaaaagc tcccgcgccc
      901 gttccttccg cttttgttcc ggccatttca gcagtttcgg cacgagggaa atgttctgct
      961 gaatggtcat atgagggaaa agtccgatct gctgaatgac gtagccgatt ttccgtctca
     1021 gctccaccgg gtcctgctcc ataatgtttt cgccatcgat aaaaatcttt ccggatgacg
     1081 gctcaatcag tctgttaatc attttcatcg tcgtcgtttt tccgcagccg ctcggcccga
     1141 taaaacaaat aaactcgcct ttttcgatat ttaaatcaat gctgctgaca gctttttttc
     1201 cgcctttata gactttcgat acattttcta atctcagcaa tccgtgcacc tccgaagggt
     1261 tccgttattt ttctgaaaag tataatcttt attataagat gaaatttgta aaataaaaag
     1321 tttacaatgt gttgaaatta tatacaatat acgtattttt tcatgttatc ccgctgacaa
     1381 tgcggatgtt cttacaatcg ctcccgatag ctcgcatatc ctgccgcatc atctttttca
     1441 tcaactgtaa aaaatatgat atattgtcag catgaaaagc cagtgaaggg atgatcagcc
     1501 gtggaaaaaa acgctcttga tatcatcggg catgctgaag agcatctcat tgagagaatc
     1561 gccgagaata tgcatacatt cggaatgccg gccacacttg gtcgtgtgct cggtattatt
     1621 tatatgaacc gcaagccgat gacgttaaat gagctgtcag aggcgaccgg gatgagcaaa
     1681 acgaggatga gccaggtggt ccgtgaaatg actgatgcca atctggcgga aaaagtgttt
     1741 gaaaaaggcg ttcgcaaaga cctttacgac gtggagcgtg attattacca gacgtttatc
     1801 tccctgttta cggcaaattg gacaaaggcg gtcagcaaaa acaaaatgct ctataaaaag
     1861 ctgaaccgcg agctgactga gcttctggaa tcggaaaatc tcagtcccga tattgaagaa
     1921 aaagcccgtc agcttttgga tgaactgacg gattggctgc attattatga ctggctgagc
     1981 cgtttgatag aattttttga gagtgaagaa gtgtttcagc atgtgccgaa aatagaaaaa
     2041 agcagcaccc gaagataacc gggcgctgct tttttaagtc aggaaaccaa tatcgggaac
     2101 atgcctttca gaccggcgcc gatcatgccg atcgccacca ccgccaaaat cagccccatc
     2161 agtcgggtaa tgacgttcat ttcggttttc ccgagcttat tgctgatgaa agaagaatag
     2221 tgaaagaaga tgaacgtcat cgcgatgacg gccgcaatgc cgataagcac gctaatgtaa
     2281 tggatgatgc cgccatggcc ggccgacaga ctcatcaccg tcgcgatcgt accgggaccg
     2341 gcgataatcg gaatcgacaa aggcgtcacg gaaatatccg ctttctcctt gctttccccc
     2401 ttctcttcat gatgaaggga ctgtacatgt gattgtttcg cgttcaaaag attataagcg
     2461 atgccgaaaa taaaaatacc gcctgcgata cgcaaggcat gaatattaat gtcgaacagt
     2521 ttaaagatca gatggccgaa gattaaaaat gccgccaaga tgataaacga cagcacggac
     2581 gccttgcgtg cgatcgctgt ccgttctttc tccgggtagc cctctgtcag tgaaagaaaa
     2641 atcggcacgt ttccgatggg gttggacact gcaaacaggg aaatgaagac atgaatgata
     2701 aatgaaaaca tgcgtacctc cttatggctt gccattattg agttatgttt tgttctccgc
     2761 tgtttcttat gcatgatttt taccccgggg tctgcttttt ataacctcag ccggacgatc
     2821 cggaaaacag aaaaaaccgt ccttgtaagg acggtttttt tctgtttgct atctccataa
     2881 gccttttccg aatttcaaca gccgataaag cattttcaat ttttttagca tgcgttaatt
     2941 tcctttttca ctctgaatca atgcgccgag agacatgata tctgtcagct ccaataaaat
     3001 tctaccatat tgggtacttt ttctctatta tcaattcata gagaaggtga tttatatatc
     3061 tttagaaaac tccgttacat ccgtcctatt ttcttttata atgtaaatat tgaacaaaat
     3121 ccctatatta cttgtaaaag gagttttaga atgtattgtt ctcaatgcgg ccatcatact
     3181 gatggcggaa aattttgcga aaagtgcggt gcgccccagc ccgggcaggg aggcgcaggc
     3241 caaacacagg gtcaggccgc tcaggccggc gccgcggcta agcaggcttc aaagcaattt
     3301 gccttattcg tgcttgatgt gttaaagaga ccgtatcaaa catgtaaaac gacaggcggc
     3361 gaacagcttg tcagcagcat catcaacatg gtgcttttct gcctggtgac gccgattatg
     3421 ttttatattc tcttatcaga cggctttcgt gatgtcagtt ttaccgcggt tgtgatcaaa
     3481 ccggcgctta cctttgcatt atgcgtattc tgcctgtatc tcttgatttt tatcgctttg
     3541 aaggccggcg gcgcgcaggt gtcatttaaa gattcgctgt ccagattcgg agcatttttg
     3601 attccgttta cagctatttt gcttcttgcc ctcattttta tgctgcttca tacaaccgtt
     3661 tgctttacca ttctggctgt cggtctttta ggagcggcgt ttgccgtgcc tccgctcatg
     3721 ctggcaagct atcagcatca gctcacggct aaagcggata tcatttattc tgttatcgtc
     3781 atctatttga tcatttgcgt aacgtttcaa ttcacgatca agcattatat aaaagaactc
     3841 atgaattatt tcttctttta aaaacggaaa ccccgccgcc tgattggcgc ggggtttttt
     3901 tattgaatgg atgttaaata aattcttccg tctttgacaa cgccgccata cgtccaattg
     3961 tatgttctga gcttcggact gccgccggct ttcgtaatat aaaactcctc gtacgtatga
     4021 atcgtcagat gagaaccttt ctgtgaaaag cttttgacat tcacttcatt aaatacttcg
     4081 gtcgtgccct cgctgtgcag ttttttgacc agtttctgct gatcagcata caaagggctt
     4141 ccctcttcta aattgcccgc catgatggca aaattgttaa ggctgacggc gcttgattga
     4201 tttgtcaggt aatcagtcat aaacgatgtg acttgctcgt ttgtcacgct gcctgaagct
     4261 gtatttcctt tggaagatgc ccatgcggat gtataggttt tcggctggtc gttttttatt
     4321 ttttttacat ttgtcccaga agaatctgag gcagggtcag ctttttcgaa aacccatttt
     4381 ttatgttttg tatcatatga gagtacataa tgaaagctcg gctcagcctc ttccatatca
     4441 ggcttcgtat tcccgtcgaa ataagcagac tcatgaagct ctttacccgt aacagttgct
     4501 tgccagcggc cgttctcttg agaaatcgca aatgaatcca gatcaaagct tgtctcttta
     4561 tactgatctt tcaaaaaggt gccggaactc ttcatgccgg ataccacttc tttcgtctgc
     4621 tctttccaag cgtaaccagc ctcggtcatc tgatcggtat ttccgtctgc catcgctttt
     4681 gtatactgct tcgttgtgtt gacaatcgtg tccataattg tttgttgtgt atcttgatcc
     4741 gggataagcg ttaattccat atcagtaccg ttgatcggaa catcggcagt tttcattttt
     4801 ccccaaggaa aatcagcctc cacggcggct gtcatggaac cgtcagttaa gagcggaccg
     4861 tatgtaacgg atttaaacgg atctttatgg acggacttgc cgtttatcag cagatcgcct
     4921 ttcgcgcttt tgaagctgtc tgccggagtg aacgtcacat cctcggcgtc taacggcagg
     4981 tcaaaatcaa cattccggct gccggccgcc tctgcctctt gctttttgac aacgtcaacc
     5041 gtgtcatttt taagcttggc ttccgccgtg tagacaccgg gtgcatacgg gccgaagatt
     5101 tgggtttcat cggctttttt gaccgtccct gttttctcgc tgttgatata aagatcggcg
     5161 cctttataat tgctggtgac gcggaaataa accggatcga ctttcagttc gtaatggtca
     5221 aacaatagaa gggttttacc ctcttttttg acgtataccg catctttttc tgatgaattg
     5281 ccgcgaagcg ttgccagcag ttcatcgtgt ttctttgcgt atgcaaggag cggtttgaca
     5341 ttggtctcat tcagcttcag ttttttgtct gaaggagtga gcagggctgc gagctttttc
     5401 gtatccccgt catgaaccgc ctgttcgaat tgatctgtga gccttttttc agatgtcagc
     5461 caggctccgg ttttatatgc ggcaatcaat aagatcagcg ctgcggcaat gccgccccat
     5521 atgaagagcg tttttttagg gatcggcttt ctcatttgtg aagcaggttc agccgctctt
     5581 acagccgcct gccgttcaag ccggcttcct ttcccgatcg gttttccgca ttctttacag
     5641 aaatgcgcct cttcgttgtt ctgtcggccg caatacttac aaaaaaacat gactttcctc
     5701 ctattcaatc tgcaaaactt gtataacttt tcctatgttt catattttat aataaagtag
     5761 aatgattttg gagttatttt gaaaaatagc tgtcgatcat aacggaggag gagaaacaga
     5821 catgcaaaaa ctgagcatcc gaaaagccgc ggagccggat gaagcgctgt atgaactatt
     5881 gctgctggcc gatccgtcga aagagattgt cgatgattat cttgtaagag gagaatgcta
     5941 tacggcttgg acgtcagacg agcttgcagg ggtttacgtc ttattgcaaa caaggccgaa
     6001 aacgatagaa atcgtaaaca tcgcggtaaa agaatcgctg cagaacaggg gattcggaaa
     6061 acagctggtg cgggatgcca ttgaaaaagc gagagaaacg ggaactgaca cgattgaaat
     6121 cggcaccgga aattccagta ttcatcagct gtcactctat caaaaatgcg gattccgcat
     6181 tcaggctgtc gaccatgatt tttttatcag acattatgat gaagacattt ttgaaaacgg
     6241 cattcaatgc cgggatatga tacggcttta tttggacctt taataaaaga gctgccaatg
     6301 atgcgataaa tccccatttt tgagacaggg atcaaaacac cttttaaaca gccaattgcc
     6361 gctcgtctat caatgattgg ctgtttaatt cgtttgaata cgaatattgt tattataaat
     6421 gtaatcgttg acagtgcgtt ttacgatggc gggcgtggtt ttgttttaac agctttgtga
     6481 tattataaga tctgatcact atgcaacacg cagctctcag gcagaattag cagctgataa
     6541 aatgtgtgta agacaaagtg tgtgttctgt ttatctccaa tcttaaaagc aatcacttct
     6601 ccattgtata catccaatat aacggacaga tacaattatt tttgtccata aggcaaatac
     6661 gcggtgtcag ttactatttt ttcaagaggg cgattagact gaaatttcta atctattata
     6721 taatcagcta cggcataagt atgcccattt ttctcacatc cttaacttgg cattgctact
     6781 gatttttctg catgatacct tgaagcattt tatggttaac acgcattccc ttttttatta
     6841 gagaagtgat gatccaatag ccctgtcgat acccatgctt tcggcataat gcgccaattt
     6901 gtttttccaa atgccctttg caatgattct tcttcacatt tttcttccag agacaataag
     6961 acgctcgtga gatacctaaa tgatcacaga aatcctgcaa aaccttctac aagttcggct
     7021 gaagtttggc ttttaacttc ctttctaatt cgttgtattc ttttaacact tcattcggct
     7081 gtcgcaaata acgattctct gcctgcagtc tctggttcgg aagtaaaccc ccagaccatt
     7141 tccgtaagta tattgcttct caacaggctg ttcgaatgta tatccccagc tctatgctat
     7201 ctaatccaag tctgcacgtc catgtattct taatattcaa tttctgtata atctctttta
     7261 tcggcacgcc tgccaatctc atgtctacac ctcctgtttg acttcaaccg gatcacttac
     7321 tcttattcca taaaaaacac ctccaagtct aatgccggat aacagtcatc cgttttcaaa
     7381 cttgaaggtg ttttttttgg tctcatctta tatgtcagtc cctttgtttt ttctaaagac
     7441 ataaagttgc aatcttttgt tggtaggaac atcaagtaat agattaaaac ttaataatcc
     7501 ataaaactcc tatgttcttt taccattcta ccttttaaat tcattaaaat aattttaaag
     7561 tttaccacaa atttctcagt tgctgcctaa aggaaataaa atctcctcat tgatcttgat
     7621 gtttaagaat ataattatac ttacttgtta ttatttttgt gtctagcata aaaataaagg
     7681 tcaattaacg atccaatcaa tattcctatg gaaaggccat acggtaaaat atcaaaaaca
     7741 actcctaaaa aaagacctaa acaaaaacct attactagaa ataccgctcc atctccttta
     7801 tagtttttca aatcaaacaa ctccttaata gtaattatga tgaatttcta tgttttttct
     7861 tttttcgttt gtgaacgata tagattacta tatacccctt ctaaagcaat cagatcttcg
     7921 tgtttaccac tctccaccac ttcaccttta tctaggacaa ttataaaatc tgaatctata
     7981 attgttgaca atctatgcgc aataaccact cttgtgcatc ccatttcact taaatatttt
     8041 gaaatcaatg attcattcac caaatctaat gaacttgtag cctcatctaa aattaaaatt
     8101 ttagggtcat ttaaaagtgc tctggctagc acgatccttt gtcgctggcc tcctgataaa
     8161 ttcataccca tttctgaaat aggtgtatta tatttcattg gcatgctttc aatttcttta
     8221 tctatttgtg ctgctttcgc tacttttctc actttttcta cactaatatt tttattattc
     8281 aatgtgatat ttttcaatat agaactatta aacaaggtaa tatcctgggg tacaattccc
     8341 atttgtttgt ataactgttt tctatctaat ttttcaagag ggatactatc aaaacaaatt
     8401 tgtccttcag tcggatcgta aagccccatt attaacttac taagagtact tttacctgaa
     8461 ccagatgaac ctactatagc aattttctgc ccttctctta tttccaaaga aatattctta
     8521 agcacctttg gagaatgttt agtataagaa aaagagacat tttcaagctt tacatttcct
     8581 cttaatttaa gattaactgc attttcaata tttttttcac attcagtctc tgtaatatct
     8641 ttaactcttt ctaaataaga agtagctaag ataaactgag tataagtacc aaataacgaa
     8701 gttgttaatc caaaaaaagt aacagataaa gaatgatacg cgataacctc tcccattgta
     8761 aatttattat caaaaaataa tagcagttct aatattaaaa taaccaaggg agcaattgtt
     8821 tgaaaaacct gagttactgt attaaccaca ttttgtaaaa tggatctttt tttgaatcgc
     8881 tttattacct cattaaaact gttattccaa gttgagaaaa tttcattttc cattcccgaa
     8941 attttaatgg ctgcgataga aaaaatagac tcgatttgaa ttgcttgaga tttactttgc
     9001 tcagctactt catcatcgat ggcctgcgcg acagcaggtc tagtcaaaaa catgaataca
     9061 gtgttaattg caaatattaa tattgttatc aaggttaatg gtatagattt aaagaacata
     9121 tacgctaaaa taaaaactac cgctcctaaa tcaattaggc cagaaattag ttgagtcgat
     9181 aaaagctctc tgaatccatt catgctattt aacctaaata acaagtcacc aggtgatcta
     9241 agatcaaaga atttaaaagg aagttttaga agatgagcaa atgtatcaac aacaagattt
     9301 ttactaagga atatattgag gcttatcatt ttgagccctc taaacaaaac aaacattcca
     9361 tacaatattg atattaaaaa tgttatccaa acaatattac ttattgaatt taaattatta
     9421 tactcaatac ttgtatctat aagcttctgt accaaaatag gtacatataa cgtcaataaa
     9481 taacttatta gagataaaaa tactataata gaaaataaca atttatagtt tgtaatattt
     9541 tttaatacac caaaccatac attcttatct tttcgtttat tgggagtaaa actttctgaa
     9601 ggaactgcat ataaaatata ggacgagaaa cctttcttaa actcttcttc tgttaatttt
     9661 cttcgtccat tagccggatc tataatataa taataatttt cctttatttt ttcaacgact
     9721 ataaaatgtt cattattcca atatgcaata aaaggaacat taattttttt taaccctaga
     9781 atagtggatt tatatatatc cgccttaaat cctttatgaa ctaataagtt ttttaactgc
     9841 ttaatagtaa gtccgtctct tccagcctcc aaaaatgacc ttaactcaaa aagagtttcg
     9901 ttactgttat aaaaacggat caacatagca caacagcaaa gtccacattc agtttgttgc
     9961 aattgtttta caataggtac tctctttttt ttcttcacta tcattcattg taactcctta
    10021 cttccattgc taacaatgaa ggattgacag gattgtgtaa ccttaataag ctgtagccta
    10081 cgcctccaag tccaagcata aatgtattta aatcaaaatg atcctgtaaa cctggaataa
    10141 aacctttatt tctaatataa ttaattgcat tttgagcttc tttaaatgct acttcctgaa
    10201 gatcaatatc attgagaagt tcacttagtt tcaataatat atctatatta ccgaaaatac
    10261 catgacataa gctatgatca gttgtttttt taaatccatc ggaaaggagc ttgcttatag
    10321 cgcaatttaa atctttatca aattctttat caactacgtt ctctttgttc tttaacagat
    10381 ttttcaaaaa agctcttgat agagctatac ctcccgcacc atgacaccaa tatactggat
    10441 cagagttccc ctctccttct cttaaatctt tccaattaga ggtattcaaa tcaaaaaact
    10501 tattttctct tttcaataac tcttttccta aagttgtgta tttttcgtct ttagtaatgt
    10561 gacccagata acaaagagcc cacgtaaaac cagaatatcc atgtgaaagt cctgttagat
    10621 aattatgttt accattcttt tctaagcatt gatataaagt attacctagt ttacaacaca
    10681 cggagtttaa aatatctaat ttagtttcct tatataggtt taataaaaaa acaataagac
    10741 tagatacccc ccctacaata tccaatggta tatctcctga aatattcatt tcatttattt
    10801 tattaatata ttttttgaat ttttcatagt atttataatc atttgtataa gtgtataggt
    10861 ggtaatatat ataggataag gaacctattc ctgtaaataa tgataaccgg ccatccatct
    10921 tatcatcact caaaaaaagt tcttcaatac ctctcattcc tgcaaaggct aaatcaaagt
    10981 actctttatt accagtttct tttccaagta aagctaagaa taatattact cctccacctt
    11041 catataagtc aaagttcaat ggacccaatt ttactttatt attctcagat attataggtg
    11101 ttacccaagt acatttgctt ctatcattat tccatattgc tgtttctaaa aataagtctc
    11161 ctatttctgt tgcacactct aaataatttt tataattatt tccaaataat ttagggcgat
    11221 atttcttatt gtgtttgttt gttcttttcc aactgtcttt tatagttgta gtaagtgaca
    11281 ttcgaatata atattgctgt ttttttaaac ttgttttact tatactttta attttgttta
    11341 atacaacatc aagtaaacac tctctaaaaa aatttactat acttgtactt ttattacaaa
    11401 tcaaatccaa agaattatac attgttgaaa aatacggaat atcattacac attaaagatt
    11461 ccaactcatt taaattcttc ttgctaaatt tatctgttac tccttccgca atatttattt
    11521 ttttaaataa ttcctttcta tcctcaaaac tagataaata atttggatga gtagaagctt
    11581 ctaaaaacct tgcatatata ctggtagctc ttaaaacttg ccttacttcc aggttgctgt
    11641 ttcctacttt ttttaccaaa tcataaaaac cacttttatt ttctaaaaca aaattataac
    11701 aatctgtaaa accttttaat atttcttcaa tataatcttt agggtctgcg gctttcccat
    11761 tatatgcagc tctgttttga gtactgttca ttattactga ttttttagtt aactgaattt
    11821 catcagttcc ttcgaaatct ataatatacg atttccatat ttctgatgtt tgattttcat
    11881 catttgatat tccgccaagg tcaaaatcaa atatagaagt ttgtaaattt aatgggagaa
    11941 gcatagtgcc aagaactgag taattaatat cctcatgaaa attatcaatt aaattattat
    12001 ttcttggttt atacatagaa ttatttttta tcagagtctc caaatcaata acaacaggat
    12061 attcgccatg cgcaattaag ttttcatgat gcaaatcgtc gcatcctata atgtgaaaaa
    12121 tagataaact tacacctact ctataaaaat agaagttcag tttttcggaa gtctcacatt
    12181 ctttataatc aataaattct tgatagccat agtctttata attaagtgtt ctagttttat
    12241 aaattttttt tagaatttta tctgaattat taacatagtc aactatacta ttaaataaga
    12301 tatcaggaga taaactatgc ggcttatata caattttccc ttggtttgtt tcaattatta
    12361 agacattttt ccctccatta tgagtgtctc cgctgctaaa ataaatattg gagacttcat
    12421 caaattcaat ttttaattct ctataaatgt cttgacgatt ttttcttaaa ttctctagaa
    12481 cttctttcaa gtacaagatt ttatttgata ttctactaga aattaaatag gttaaaacag
    12541 gatacttatt caaaatttca gccacatatt cactcttaaa aattagatta ttataattct
    12601 tatagcgtga ccttgaatct tttccttcta ataaaccttt ttcttttctt tcattaatat
    12661 caacgattaa agttcttata cataactgaa ttaattcctg gttaaaagcc tctaatgcac
    12721 tacttataat tttatgtttg ttaagtttta cattattttc cttacttgcg ttttctaaag
    12781 tattaactaa tctttgttga taaaaatcta aaaagaatgt ataaaagttg ccaaagtaat
    12841 ctttgttttt tattcttaat ttttctactt cgtttgtcgg cgaactgaaa ttaattacag
    12901 catctgtgat gaaattattg ttttcatagc taatatccat ttataacctc tccaaaagat
    12961 ttaaaagatt taatagagaa ttgttttaaa aaacaattct ctattaacac attatgttta
    13021 tttgttacac tgttttgtac acgctgatgt tggacatgat gctgcactta aagtaactgt
    13081 aaaagtcgtt ccagtgagtc caatagttgc agttaaaacg actgttggag tagctccacc
    13141 agtagcatta tcaccattag ctaatgatat aagttcgtct tcttcaataa aacctgaagc
    13201 ctttttgacc atatctttct tcataattct ctcacctcct ttcaagtatg actttgaata
    13261 agagtgttaa agcttattct agccataaaa aattaggaac aatttccgga gcataatttt
    13321 tgatcattga gtaacctatt cctgataatc cgatcattaa actatatgat ctagtacaga
    13381 ctaagtctct ctttctccat ttcttggtca aaacattttc aaataggtct tgataagttc
    13441 ttaaacatct attcttcaaa ttaatattgt tagttaaatc agaagcataa ttcaatatag
    13501 aaagcacacc taaatctcca tgacaatatg tagggttatt gccaatgcca ttacgaatag
    13561 aagaatctat cgcagtcgat atttcttttt caatgtactc gtcttcaaaa ccattatctt
    13621 ttaaaatcaa tttacttaaa agtatacctg gagctccgtg acaccatcca ttagctaact
    13681 tatctttatt ttctgtggta taccaattat tgtggtcttc agagtacaat ctcctttcaa
    13741 atcttaaggc cttttgaatg acttccaata atttttcatc atttgttaac ttaaaatatt
    13801 tatataagta tgcgataaaa ccagaattac catgggaaaa ccctgaatat gctgctgaaa
    13861 atttccctgg ccaagatatt tgctcctcaa aatttttcgc tacacttaat atatgatcac
    13921 agtgagtatg tgagatcttt aaaatttcct ttttgctatt ctcttcagta atatctggta
    13981 ttatggaaag cgtaactgct aaactaccta aagaccctcc tattaaatcg tacactttat
    14041 cgaatttacc taacttcgat aaaacactga tgttttcaag cgaggctccc tttaattctg
    14101 aatcttcaaa taaattagat aacttattta atgtataaaa atatcctgat ataccttgga
    14161 atgcaccaat taaatatggg tgatcttctt ttatttcaga gataaacttc tgtattggtc
    14221 tcatagtttc aatagctgct tgtttaaaat cctttctgtt aaggatttcg cccaagtacc
    14281 ctaaaaataa agcaatccct gaattaccat tatatatatc gaaccccaat acatttgcat
    14341 tccaaatgtc ttcctcaata ccctcaagac tagggcctat ccacattcta tctttttgtt
    14401 ttttatttat gccacataca ctgttgtcaa ctataaattc gcctatctgg gttgcttcat
    14461 ctatccaatt ttcagactta attttattta agtttgcagc tttagagaat tttatatcag
    14521 taacttcttt taatcttttt tcattactaa tgtaagacat ttcaataaaa tcaatctgtc
    14581 ttttcaaatc ttctttcgat agattaaaaa tcttttgctt tactgttttt attggaggtt
    14641 cttccagaat actgtgaatt ttttcccctc tagaatctat taaattttca tgttcaatag
    14701 aggatgtaaa aaatggaacg tccccagtta ataaatcttt atattctgag ttcaatatat
    14761 ctttatactc ttgtatataa tcgatgccga ttctatgtaa aataatctta cgtctatagg
    14821 tatctctcat aaaatctgga tgacttgaaa ttcttaaaag ctgagtgtat aagtaagtag
    14881 gtctgaagat aaacctgcta tttgtttctt taaaagtttg agaaatttta ttccagaatt
    14941 catctttatt taacatcacc caactatata aacttgcaaa accatcttta atttgtcccg
    15001 tataattttc tgaatataag taagaccctg ttttaatgga agggttattt aattgaggtt
    15061 taatgaaagt attttttctt aaaattttaa tagtatctgt tcctgcattt tcaattacta
    15121 atgatttatg aggagagagt tgttccttat gcgcacctaa tccccctata tctagactta
    15181 tgtctttgtc tcctactctc ttagaaattt ttgtaggcaa taaacttatt gactgtacag
    15241 agttatcaac taattcagtt gctttaacaa cagctgactt tttatcaatt tggtcaacct
    15301 ttagtcttgc atgaaataat gattctaggt caactaatac tgggaaagaa ccatgggcta
    15361 ttaaattttc atgatgaaaa tctactgaat ttagaagata cagtaaacaa agaagattac
    15421 ctgaacgagt ataaaaatca tttgcttctt ttttattaaa acaactttta taatctatgt
    15481 gctccatcca acccgaatca tttactgtat gtatttgaac tcttttgaaa tttaaaattc
    15541 ccggtatgtt tttcccgccc aaccaatata atacttcctg aaaaccttgt tcaagcctta
    15601 aatctctagg tttataaatt attttcttgc cacttttaaa atatattgtt gaaacagatt
    15661 ttcctttttg atgagtatct cctagaccgg tggttatatt tgttattgca cctaaatcat
    15721 tatcagagtt gaatttagag tttaatgaac taatttctcg ttttgtgttt tttattattt
    15781 ccattacata tgtgaaataa tcatcaatcg ttacacataa taaacttgtt aatacttcat
    15841 attctttata aacacttttt aaaaatgatt catcatttaa agatacaact aaaaaatgat
    15901 ttagtctttc ttgcggggta gtcccctcta aattcccctc taatcttgca atattcactt
    15961 ccaaaacaag aaccctaaaa gctttttcaa acattaaatc cactatatgt ttaattacct
    16021 ttttcacaaa ttcatcctca ttatctactg catcttcaat tcttactttt actatgaatt
    16081 cttcaatttt gcagttaaga aaaggagaaa aaaaatgaaa aaatggatta tgctctaaaa
    16141 attcttcaga atttctcact aaaaaatcac tttttttatg atctaagact ctatcaatat
    16201 ctataatgtt tgtattttgc tcaatattag tatcgtctct aattaatgat tgaatcgtct
    16261 taccagatac atttaaaaaa atcttttgta attcatcttt attgttaacc tcaggaaaca
    16321 ttttcatcca gtattggaga ttgtatttgt tagttttcaa agttaatgat cctaccttaa
    16381 tattttttca caaaataggc agtcaattga actgcctatt ttatacttat ttcagcaagt
    16441 accttgacat tctttagtac ctgtacaaac cttgccttta tttccaagaa cctcacttac
    16501 taaaatgccc cccaggctag tagttgtggt attccaggta ttgaaagctc ctgaaacttc
    16561 atgttcttta atttcttcaa gaacatctcc acatgggtct atcaaattta aatcttttgt
    16621 cactttcaat tctggtgttt ttaatatctt tgtcttcttc atactatcta cctcctcatt
    16681 ttttactgga taaaatctct attaacctgt tcaataataa tctaccatat tttcctatag
    16741 taaacaatgg gttttatgta atttttttat ttcgcgagat tctcggggta ttttatactt
    16801 tattttaaaa gggcagttat actagaaaaa agtagtcctt tgtttttgtg aatgtaattt
    16861 tcaaaatgct ttaggaaaga aacaaaacga ttattacatt acttgaaaaa atatcgtagg
    16921 tcctgtcttt tgcaaataaa agaacataca gttatattac acgggaacag gaaagaatac
    16981 tttcttttgg agttgtcatc aaaattattt agattaataa ggaattaagt aactattatt
    17041 ttgttctgag aggtgcgtca acacaatcag ctactacctt aactttttat aagtattata
    17101 tgcagctaat ttcgggctgt tgtagaccat tgttttttta tctaggactc agctaattac
    17161 tatccgttct gtatcttaga ccgctgaatt agggatataa gtatctgtaa tcacaaaatt
    17221 gtttacttct cgtttttaga aatattgaac ggatcaaacc atgctttgtc atcatctata
    17281 ctcgcatcct tacattaatt gaatgatttc attaatttga agaagtgttc gagttggtga
    17341 gtttttattg agctgatacc atgatccaat gtatacagtt gttcaaacat ggtttatttt
    17401 ttcagtactt ctctcggggt ctaagagagt tttctcctga tgcagtaacc agattcctct
    17461 agatatcggg agttccatat cataaaatgc aaatgtcaac attgcttgta tgttttcttg
    17521 attccaagcg tctgctattc gctgaatcca cacttacacc gtaaaatgta acaaccatcc
    17581 tcctctgggc tttaaagctt cactgtcctt tatcaagacg gctagtgaaa cttttgcctc
    17641 aaatattcga tgcgagtaat attagtagat ctgtactttc gaacacccac tcatcaaggg
    17701 agatatccgg ttttatgcgc taagctcaag cgtagttatg atttctttat tcaccctatt
    17761 gtcatgactt ttaaaagtgc tgcatcttgg tgttcggtct taaatatcca catttccaac
    17821 ctgatattgt aggaaatggg taaagataaa ctgttttcga tcattcaaac actccaatca
    17881 aaatcaaaaa aaccctgact gctcttgtca gggtaataga aggtcaactc ttccacacta
    17941 aagggcttgg ctgcagatgc agccaagccc tttttatgct tacttattca agttatagaa
    18001 agagttgata ccgtggtatt gagcagtttc agccaactga tcttcgatgc gaagaagctg
    18061 gttgtatttc gcaacacggt ccgtacggga cggagcacct gttttgattt gtcctgcatt
    18121 agttgccaca gcgatgtcag cgattgtgct gtcttcagtt tcacctgaac ggtgagagat
    18181 aacggcagtg tagcccgcgc gtttcgccat ttcgatcgca tcgaatgttt cagtcaatgt
    18241 accgatttgg tttactttga tcaggataga gttgcctacg ccgtttttga taccttcagc
    18301 aagctttttc gtgtttgtaa cgaaaaggtc gtcaccgaca agctgaactt ttttgccaag
    18361 acgctctgta agaagtttgt ggccttccca gtcgttctcg tcaagtccgt cttcgataga
    18421 gatgattggg tatttagaaa ccatttcttc gtaccagtca accatttcag cagatgtttt
    18481 cacaacgcct tcgccagaca gatggtattt gccgtcttct ttgttgtaga actcagaaga
    18541 tgcagcatcc atagcaagct tcacttcttc gccaggtttg aagccggctt tttcgattgc
    18601 ttcaacgatt gtttgaagcg cttcttcatt agaaccaagg ttcggagcga atccgccttc
    18661 gtcacctaca gctgtgttca ttcctttagc agaaagaact gatttcaggc tgtggaagat
    18721 ttgagcgccc atgcgaagcg cttcacggaa gttaggcgcg cctacaggca taatcatgaa
    18781 ttcttgaatg tctacgttgt tgtcagcatg ctctccgccg tttacgatgt tcatcatcgg
    18841 tacaggaagc gtttttgagt tgaatcctcc aaggtattgg taaagaggaa tctgtaagaa
    18901 atcagcagct gcgcgcgcac aagccataga tacgccaagg attgcgttcg caccgagttt
    18961 gcctttgttt tcagttccgt caagctcgat taaaagctga tcgattgcgt tttgttcagt
    19021 tacgtcaaag ccgagaagct ctggagaaat gatttcgttt acgttgttaa cagcagttaa
    19081 cacgcctttt ccaaggtaac ggtctttgtc gccgtcacga agctcaaccg cttcgtattc
    19141 acctgtagaa gctccgcttg gcactaatgc gcggccgaaa gctcctgttt ctgtatatac
    19201 ttcaacttca actgtcgggt tgccgcggga gtcaaggact tcgcgtgcat aaacatcaac
    19261 aatgtatggc atgagtttgt ctctcctttt gatttacgct tatttttgaa ttaaagatgt
    19321 tccggtcatt tctttcggtt tttcaacacc gagaaggtct aataacgttg gtgcgaggtc
    19381 gcctaggatt ccgccttcgc gcagcgtcac gccttctttc gtcacaatga cagggactgg
    19441 gtttgtcgta tgggcagtgt gcggttcgcc tgtttctgta atcagaatgt ccgcattacc
    19501 gtgatcagcg gtaatgatgg catgtccgcc tttagcgata atagcgtcaa ccacttcgcc
    19561 taagcattcg tccactgctt caattgcttt aatcgtcggt tcgaccattc cggagtggcc
    19621 gaccatgtca gggtttgcaa agttcaggat gatcgcgtcg tgcttgtcag ccgcgatttc
    19681 ttttacaaga gcatccttca cttcatacgc gctcatttca ggcttcaggt catatgtcgc
    19741 gaccttcggc gagttaatga ggatgcgctc ttcgcccggg aattcttctt cgcggccgcc
    19801 gctcataaag aacgtaacgt gcggatactt ttcagtttct gcaatgcgaa gctgttttaa
    19861 cccgtgctgt gctaatactt caccgaccgt attgtcaagg tttaccggtt taaaagccac
    19921 atatccgtca acagattcac tgaagtgagt caggcagacg aaatacaggt ttttcggatg
    19981 attttcaccg cggtcgaaat cgcggaaatc tttgttggta aacgtgtttg aaatctggat
    20041 ggcgcggtct ggtctgaaat tatagaaaat cacagaatcg ccgtcatgaa ttttcgcaac
    20101 gggttcaccg ttttcttttg tgatgacgga cggaatgacg aattcatcat gaatgccgtt
    20161 cgcataagaa tcgtcgacta catccatcgc gctgcggtaa gacgggcctt cgccgtaagc
    20221 cattgcgcgg tacgcttttt ccacacggtc ccagcgtttg tcgcggtcca tggagtagta
    20281 gcgtccggaa atgctggcga tttcgccgac accggtttct tcgatctgct cattcagctg
    20341 ctgaatgtaa gttttcgccg tttgcggacc tacatcgcgg ccgtcgagga aaccgtgaat
    20401 atacaccttc gtcagtcctt cacttttcgc aagcttcagc agcgcgaata aatgattgat
    20461 gtgactgtgt acgcctccgt cagaaagaag gccgaacagg tgcagcgctt tgtcgttgtc
    20521 tttcgcgttt ttgatggcgt caaggaacgt ttgattgcgt tcgaattcgc cttcgcggat
    20581 ggcaacgttc acgcgtgtta agctttggta cacaatacgt ccggcgccga tatttaaatg
    20641 accgacttca gagttcccca tttgtccttc aggcagtccg actgcttcgc ctgatgccgt
    20701 cagcgtctga tgagggtatt ggttccaata acggtcgaaa ttcggttttt tcgcttgtgc
    20761 gactgcgttt ccgactgttt cattgcgtaa tccgaaccca tcaagaatga tgagtgcagc
    20821 tggtttttta ctcatattga ccttcctcca ataattgaac gaatgactgc ggttcaaggc
    20881 ttgcgccgcc gaccaaagca ccgtcaatat cggactctgc catatattct ttaatatttg
    20941 caggttttac gctgccgccg tattgaatgc ggagcttgtc agcagtttcc tggctgaagc
    21001 tttcagcaac gactttacgg atatgcgcgc agacgtcgtt tgcatctttc gctgtagaag
    21061 atttgcctgt tccgattgcc cagattggct cgtacgcaat aacggaagcg gcaacttgct
    21121 cttcagaaag acccgcaagc ccttttttca cttgatcggc aacaagatca tttgtttttc
    21181 cggcttcgcg ctcttcaagc gtttcaccta cgcaaatgat cggcacaatg ccgtgtttga
    21241 aagcggcatg cgcttttttg ttaactgttt catcagtttc agcgaacatt tcacggcgct
    21301 ctgagtgtcc gataacgcag taatccacgc caaggtcttt cagagcgacc gggctgattt
    21361 cacctgtgaa cgcaccgttt tcttcaaaat gcatgttttg ggcgccgact ttcagatcag
    21421 ttcctttaac agcagaagtc agcttttcta agaaaagagc tggtgcgcaa acaacggctt
    21481 ccgctttgtc tgctgctgga atggaagatt tcacttcttc aacgaagctg acagcctcgc
    21541 cgagtgtttt gttcattttc cagttaccgg ctataattgg ttttctcatc tgttccactt
    21601 ccttatagca gtttttattt atcgttcagc gcagctacac ccggaagctc tttgccttcc
    21661 atgaattcaa gggatgcgcc gccgcctgtt gagatatggc tcattttgtc agcaaggccg
    21721 aatttttcaa cggctgccgc agagtctcct ccgccgatga cagagtatgt atcgtttgcc
    21781 tctgccaatg cttcagccac tgcttttgtg ccttgagcga acaagtcgat ttcgaatacg
    21841 cccatcggtc cgttccatac gacaagtttg ctgtttttga taacttcagc gtacgtttcg
    21901 cgggttttcg ttccgatgtc gatcgcttct aaatcacttg ggatctcaga gatcggcacg
    21961 atttgaacgt ttgcatcgtt agagaaatca tcagcaacga gaacgtcttc cggcatatag
    22021 aatttaacgc ctttttcttt cgcgcggtcc atgaatgatt ttgcaagttc gattttatct
    22081 tcttcaagaa gagatttacc gacttcatag ccaagcgctt ttacgaatgt gtaagcaaga
    22141 cctccgccga tgatcaggtt gtccacttta tcaagcagac tttcgattac gccgattttg
    22201 tcttttactt tcgcgccgcc gatgattgct gtaaacgggc gctcaggatt tgtcacggct
    22261 ttgccgagaa cgtcaagctc tttttccatc aggaatcctg caaccgccgg cagatgctcg
    22321 gcaattccgg ctgtagatgc gtgagcacgg tgggcagcac cgaatgcgtc attgacatat
    22381 acatccgcaa gctcagcaaa tgctttagca agctcaggat cgtttttctc ttcaccaggg
    22441 tagaaacgta cgttttccaa tacaagaacg tctccgtcct tcatatcaga aatttgtgct
    22501 tttacagcat cgccgtaagc ttcatccgct tttttcactt cttttccgag cagttcgcct
    22561 aagcgtgcag cgacaggagt taaacgaagc tcctcaacca cttcgccttt cgggcggcct
    22621 aagtggctcg caagaaggac tttcgcgcct tggtctgcaa ggtgtttgat tgttggaagc
    22681 gcagcgcgga tacgagtatc gtctgttact tccccgtctt tcattggaac gttaaagtca
    22741 acgcggcaga atacgacttt gccttttacg tcgatgtctt ttactgtttt tttattcatg
    22801 ccttaggaga tcctccttca aaatggtttg catagcacga aaaacgtgaa acgtgaaacc
    22861 gcctcatgat gcttccgccg cggggcagat tgcagcttcc gggcacgggg cagatcgtct
    22921 tctgagccag ggcaggcggc tcagaaaacg aaagtgccgc ggaaacttca aaacgcggac
    22981 gttctgcagc aatccggcgc tttctgaaag ccggttctca tggaaaaagg gaaagggagt
    23041 ccgtcccctt cccttgtccg ctttcattat agcgtttctg tccgaaagaa ccaagtccgg
    23101 ccctttccgg gagctatgaa ttaaagacct tgttttgcga tgtaagctgc aaggtcaaca
    23161 acgcggttag agtagccgct ttcgttatcg taccaagaga ttacttttac catgctgcct
    23221 tccataacca ttgtagaaag agcatcgatt gtagaagagt tagcattgcc gttgtagtct
    23281 ccggatacta atggctcttc gctgtatcca aggattcctt taagatcgcc ttcagccgct
    23341 tctttaagag ctgcgtttac gtcttcagcc gttacgtctt tgttaagttc agcaactagg
    23401 tcaacaagag aaacgtttgg agtcggcaca cgcatagctc cgccgttcag tttgcctttc
    23461 agttcaggaa gaacaaggga aactgcttta gcagcaccag ttgatgtagg aatgatgttt
    23521 tcagctgctg cacgcgcacg acggtagtct ttgtgcggaa gatcaagaat ttgctgatcg
    23581 tttgtgtaag agtgaacagt tgtcatcata ccgcgtttga tgccgaattt gtcgttaagt
    23641 acttttgcaa acggcgcaag gcagtttgtt gtgcaagatg cgttagagat aacatggtgg
    23701 ttagccgcat cgtatttgtc ttcgttaaca cccataacga ttgtgatatc ttcttcgtta
    23761 gcaggtgcag agatgataac ttttttcgcg cctgcttcta agtgtttcgc agcgtctgcg
    23821 cgttttgtga agaaaccagt agattcaact acgatttcaa cgccttgttt gccccagctg
    23881 agtttcgcag gatcgcgctc agcagaaact tcgattgttt tgccgttaac aacaaggttg
    23941 ctgccgtcaa ctttaacttc tgcatctaat tttccgtgta cggaatcata ttgtaaaaga
    24001 tgagcaagca tgttagcgtc tgttaaatcg ttaactgcta ctacctcaac ttcaggattg
    24061 tttaatgctg cgcggaatac gttacgtcca atacgaccaa aaccgttaat accgactttt
    24121 actgccatga ttatttcctc ctttaaataa gtgagagata tttatattga gggactgtta
    24181 tcccttaata acttctttgc ggctccttcg tccgtgacga gaaccgtgtt tcgctgcttt
    24241 ttaaaataag cttcgattgc ttccgctttt gatgatccgc ccgctaccgc aataatgtcg
    24301 ggaatggcat cgaggtcatc gagctgcatt ccgactgaat gcaccttgtg aacgacttct
    24361 ccgtccgcat taaagtagta gccgaatgcc tctgtcaccg catgattgtc atctattttc
    24421 ttcaaatctt ccaaaggcgt gtttcttcgc tccgccattg ttctagcttc gccgattccg
    24481 tgaacgagca tactcgctga tttaatcgtg tgaagcacct cttttacgga aggttcttca
    24541 ataatagatg agtaggcgcc ttgtgacagc tgtccgggaa cgaacaaaag ccggtaagtg
    24601 cctgaagcct tttccgccat atgcgcgcat atggtgttcg cctggttttt cacgtcttcg
    24661 cctaaaccgc ctcttgcggg cacaaacagg agctcgcggt tttttgaatc cggcgtcatc
    24721 atatcggcga cggcttcaat tgtcgtaccg ccggttacag cgacgatatt tttgcctgaa
    24781 aatctctttt tcatacatgc aacggccgct ctccctaatt cttttttgac ccaaggagat
    24841 tggtcgctgt ctccggaaac aataatggcg tctttcagat taagccgctc ttttaatgtc
    24901 ttttccaaaa gcgtcaatcc taaaacatcc ttcatcgtat cttccagaat cgaaagcagt
    24961 gaatagccct cttccgtcat tgtcatgccg tttgttttaa tatcgatgag attctgttct
    25021 ttcaagaact gaacctcgct tctgagaacg cgctcggtca atccgagact ggctgcaaga
    25081 cttctgcggc cgatcggttc tgtaagcctg atatactgca agatttcaaa tcttttctgc
    25141 atcacaagca aaagatcagg caataatttt ttttgagctt gtattaactg gttcatgact
    25201 caaacgttcc ttcctattca tactggacag aaaatgtccc gctatgacaa aaaacgtccc
    25261 atcatagcca aaaaaaatta tgtctgcttt ctttaattat tttaacagga tgacattgtt
    25321 aattcaactg ttaaaggtca attcctcgac attcttcgca ggatttacca gtatctcctt
    25381 gatacagtca ttatatacag aaacggaatg aaggtgacag acaaaagccc gccggagcgg
    25441 acttttgtcg taaaacgctt tcattttatc cagagttttt ctatttcttc taatgattta
    25501 tttttcgtct cagggcagat cgtcacgaca aacaagaaac agagaatatt aatgacggcg
    25561 aatatccaga aggtgtacgc gagccctaac ccgctgatca tcatcggcac gaactggccg
    25621 atcgcccagt tggcccccca taagaatatc gtcgcaatac cggcggcgcg tgcgcggagg
    25681 tggttcggaa agatttccga aatcatgatc cacgtaatcg gcccgactga tacgcagaaa
    25741 gcggcgacga atcccaatat gatgacgact aaagccggac cgctcgccag ctgaaaataa
    25801 aaggatgccc cgattaagat catgaacagc gccataaagg cagatccgac ccccatcagc
    25861 tttttccggc ctaccttatc gactaaaaga accgcgataa tggtgaaaat cacttcaacg
    25921 acaccgacga tgcatgtcgt gataaacccc gcattctgtc cgaagcccat cattttgaaa
    25981 atttccggcc cgtaatacgt aattgcgttc atgccgatga cctgattgaa taaagccagc
    26041 agaatcccga tcacaagcgc ttttctcagc cccggtttaa acagctgaga caatgaaccc
    26101 attttttcta attgtaaaga cgtttcgatt tgtttgattt cttctttcgc ggtctgctcg
    26161 ccgttaatgc gcgtcagcac ggcgagggct tcattccggc gccccgcttt cgcaagccag
    26221 cgcggacttt ccggcacgat aagcagcacg ataaaaaaga tgacggacgg aatcatgccg
    26281 taagcgagca tccaccgcca gccggtgtgc actccccatt catacgagcc ggactgctgg
    26341 acggccaggt taataaaata
//
