LOCUS       NZ_CP017780            20687 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Amycolatopsis sp. BJA-103 chromosome, complete genome.
ACCESSION   NZ_CP017780
VERSION     NZ_CP017780.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. BJA-103
  ORGANISM  Amycolatopsis sp. BJA-103
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Isolation and identification of a potent feather degrading rare
            actinomycete Amycolatosis sp. BJA-103 isolated from the rhizomes of
            Valeriana jatamansi Jones with abundant antibiotic biosynthetic
            potential
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:58:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,631
            CDSs (total)                      :: 8,562
            Genes (coding)                    :: 8,496
            CDSs (with protein)               :: 8,496
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 31 of 66
            Pseudo Genes (incomplete)         :: 47 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 13 of 66
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:43:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7027475
            Orig. end                         :: 7048162
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017780.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from B415, College of Life
            Sciences, Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="32"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20687
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20687
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10687](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10687)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    complement(24..39)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            complement(108..1040)
                     /locus_tag="BKN51_RS31190"
                     /old_locus_tag="BKN51_30745"
     CDS             complement(108..1040)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1252: cation ABC
                     transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028570.1"
                     /locus_tag="BKN51_RS31190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30745"
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="WP_101611037.1"
                     /transl_table=11
                     /translation="MNSRRTKSVFAAVSALAVLALGATACASGDKASTASGSQNAAAAN
                     PGGGEKIKVVASTDVWGSVVTAVGGDKVEVTSIIHDPSADPHSYETTASDAIAAKNAKL
                     TLSNGGGYDEFFSKLADQAAGAQKLVAVDIAATGNENEHVWYSLPGVEKIADQVAAKLG
                     EIQPASKDAFTANATAFKGKTQELLKKVTGLGASGGKVVATEPVAHYLLDSAKVTDATP
                     PAFAEAVEAEQDVPAAALNQVKQLISGKQVKALINNAQTTTPVTQQVVGDAKSAGIAVV
                     DVTETLPQGVTDYIAWMTKSVDALAGALK"
     misc_feature    1031..1045
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.96"
                     /tool="antismash"
     misc_feature    1089..1104
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.05"
                     /tool="antismash"
     misc_feature    1091..1105
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(1093..1104)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     gene            1241..2341
                     /locus_tag="BKN51_RS31195"
                     /old_locus_tag="BKN51_30750"
     CDS             1241..2341
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005441636.1"
                     /locus_tag="BKN51_RS31195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30750"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_101613561.1"
                     /transl_table=11
                     /translation="MGRPIRTRRQATLASLAAELGVSRTTVSNAYNRPDQLSPELRRRV
                     LETARRLGYPGPDPVARSLRTRKAGAVGLLLTENLSYAFRDPAAIGVLEGLALACEDAG
                     VGLHLVPASPGREDVAAVHRAGVDGFVVYSVPDDDPHLGAVLERPVPTVIVDQPRVDGV
                     DRVGPDDAAAVTAMAQHLISLGHRQIGVLCMRLGRERNDDFVSIQRQSAAHFHVQRIRL
                     EALAAAFSAAGVDWSTVPVVERFDHTVDDGASAARQLLDAYPQVTAVICTSDILALGAL
                     AEAERRGLRVPQDLTVTGFDGITEAERSGLTTVHQPVLEKGKAAGKLLLSSADRVGPKV
                     ITLQTELRVGRTSAPPRTAEERWFGP"
     misc_feature    complement(1252..1269)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            2393..2884
                     /locus_tag="BKN51_RS31200"
                     /old_locus_tag="BKN51_30755"
     CDS             2393..2884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015097825.1"
                     /locus_tag="BKN51_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30755"
                     /product="carbonic anhydrase"
                     /protein_id="WP_101611038.1"
                     /transl_table=11
                     /translation="MTSIDVLLKRNQELGDVTPGDRSSPRPSLQVAVLTCMDARIRVFE
                     IFGLLQGESHVLRNAGGVVTDDMIRSLALSQRKLGTREVLIVQHTECGLSMVTEDDFKD
                     ELEESTGLRPTWAVEAFREVEDSVRRSVQRVRRSDFLPHRDNVRGFVYDVKTGRLSEVA
                     "
     misc_feature    complement(2887..2901)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            3005..3880
                     /locus_tag="BKN51_RS31205"
                     /old_locus_tag="BKN51_30760"
     CDS             3005..3880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165321.1"
                     /locus_tag="BKN51_RS31205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30760"
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="WP_101611039.1"
                     /transl_table=11
                     /translation="MGVDADVLTGWFDEVGRDLPWREPECTAWGVLVSEIMLQQTPVAR
                     VQPIWLEWMARWPVPSALAASSQGEVVRAWGKLGYPRRALRLHAAAAVIAAEHGDVVPS
                     DVDTLLALPGIGAYTARAVAAFAYGKRAPVVDTNVRRVVARAVHGAGDAGPPSNTRDMA
                     DVEALLPKEDAPAAKLSAALMELGALVCTARSPRCADCPIYDDCAWQHAGKPAYAGPAK
                     QVQKFAGTDRQVRGLLLDVLRGTEGPVEKARLDLVWDESGQRDRCLDSLLVDGLLEQTG
                     DGLFALPGEH"
     gene            3969..4934
                     /locus_tag="BKN51_RS31210"
                     /old_locus_tag="BKN51_30765"
     CDS             3969..4934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632025.1"
                     /locus_tag="BKN51_RS31210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30765"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_101611040.1"
                     /transl_table=11
                     /translation="MADFDRRTALKGGLTVSAVGLLGTTTFSAAAVAAPGAAEPKIHDT
                     AAWSARPPNGTIEVQNHKPTYIVVHHTVDPGNVTDYSLEHAFWASRAIQNFHMDTRGWV
                     DSGQQFTNSRGGHITEGRHRSLEVLRGGTKHVLGANVGNNNSTCIGIENEGLYSTENVT
                     PALWDSLVKMVAYIASQYGISPQFIKGHRDFNSTECPGTVLYNRLPELRTAVGGLLGSA
                     SPKADLPEWPLLKPGDTGPRVRVAQELLRARGFAVPTDGLFGQSTKDAVSTLAAKHGLE
                     RDLCGATAATDETGFLGSDVWPLIVGPGTDLRALKARLAG"
     misc_feature    complement(3970..3984)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(4879..6033)
                     /locus_tag="BKN51_RS31215"
                     /old_locus_tag="BKN51_30770"
     CDS             complement(4879..6033)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337737.1"
                     /locus_tag="BKN51_RS31215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30770"
                     /product="MFS transporter"
                     /protein_id="WP_101611041.1"
                     /transl_table=11
                     /translation="MLPIPALLALTTTVFLGCLTEVLPAGLLLGMSEDLGVSPSATGQL
                     VTVYAITTALTAIPLTSATLRVPRKRLLLLLIAGFLVTNLLIAVSSSYPLILAARIFSG
                     ALTGVMWSLVAGYAMRLAPPGLTGRALAVAMSGTPIGFALGVPAGTALGELADWRWAFA
                     AMALITVPLMAWVMAVVPAVPADPAASTRPLAASRLPGMRPVLATVALFSLGHNVAYTY
                     IGPVLAGLDVAGMLGVALLVFGCATVGGLVVVGTALDRHPRAVLMFCTGATAAAIVLLG
                     ISDGVHGLVLTAAALWGLAFGGAPTAFQAVTALIAGPTADAAQSLTIAAWNGAVAGGAL
                     IGGLLLPLGTSSLPWVAAFVILLPLAFSRRVVLSAPADRSRALR"
     gene            6201..7658
                     /locus_tag="BKN51_RS31220"
                     /old_locus_tag="BKN51_30775"
     CDS             6201..7658
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165327.1"
                     /locus_tag="BKN51_RS31220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30775"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_101611042.1"
                     /transl_table=11
                     /translation="MTVRIRWQEPLCTALLATTMIGTCQAPAAAQPAPGSDGYVHVSPD
                     GTVLGADPYYPKDGNGGYDVDKYALALDYSPYSMLLNGKATITATATQDLSRFDLDLRG
                     LTVRSVTVDGVPAAFRRAGEHELVITPRTPLAEGTRFTVVVGYDGRPEPIGTARGRVGW
                     LGTPGDSAVATGQPRSAMTWFPVNGTEVDKATLRVSVTVLDEFSVLGNGLPVSDVPAGF
                     GRHTVTWSEDTALAPSTAMLGIGRWEVERITLPGGRTAINAYHPCAVDKRKIGGQLPEV
                     LEFLTGKFGDYPQSAAGGLFLDRSLGYTHGAQTRPVYGRTATIADLVYATAYQWWGAGV
                     SGKMWRDTLMPESIAQYAVWLWDEAKNGVDLDRRYREMVAKVSGDTGFWAPKITDPGKG
                     TEFAPTTKAVLMVHALRRTIGDDGFFQIMAGFPMINPQGNQNWHDFELYVSAMTQLDLG
                     AFNHAWLDGTVRPPDELLYPGPLRPSR"
     misc_feature    6837..6839
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7687..8688)
                     /locus_tag="BKN51_RS31225"
                     /old_locus_tag="BKN51_30780"
     CDS             complement(7687..8688)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028563.1"
                     /locus_tag="BKN51_RS31225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30780"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_101611043.1"
                     /transl_table=11
                     /translation="MTKEFDVVQLDVHHLRVIRAIADTGSLSRAAIALGVTQPAVSAQL
                     KRLENMLGYQLFDRREGSVTPTPMGELLLRRTAALLPQLDKLLEDIEQRVCPSGPPDVV
                     RVASVASALVAHLPSLVHRLWPEVSEVQVVHDDHPERLLPLLAQRRAELGLVKEYPGYE
                     LEIPASVDTAVVVTEPTFVLLPEGHPLAREEVVDLRALRDESWVMVSDSSAATFTKYFA
                     DTCARYGFSPSVAHQVTSQQVALMVVRAGAIGLSQPICDPRNLGVVTRPLLGDVLPRRH
                     VLAWNRETFVAGRREELLAAVVETYWAEARTAPVYAGYLESHGDLGTRPDDG"
     gene            complement(8685..9998)
                     /locus_tag="BKN51_RS31230"
                     /old_locus_tag="BKN51_30785"
     CDS             complement(8685..9998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165331.1"
                     /locus_tag="BKN51_RS31230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30785"
                     /product="cytosine permease"
                     /protein_id="WP_101613562.1"
                     /transl_table=11
                     /translation="MEHDDFSLRRVPAERRYSWVSVALQRFGQVSSFHQFLLGAVLGFG
                     MTFWNAVLAITIGSVLLEIITILMGIAGTREGLSTSVLARWTGFGTGGSSLVGLLMTLS
                     LAGWFGVQNDVFAHGLHALMGGPPVWVWALAGGALVTAIVVFGFHAMAWTAYLTVPAFL
                     ALAGYSIVTALDDHSLPALMAEPPPGPAMSLAQGTTLVAGAFIMGAIMTPDMTRFNRTA
                     SDVVKQTLVSITLGQYLIGLIGVLLAHAAKSADVVGIITSSSGVLGTLILVTAILKIND
                     WNLYSSSLGLVNTVQVLLSRRLDRTTATLLLGGLGTVLSAIGILDHFTTFLTWVGVLTP
                     PVAGVVIAEYYVVRRWKPDLDATRASGELPSSCPSWVPVALICWVAGATVGAWLPWGIP
                     TVNSVFGAFLLYVLLGRRTRVTGGSVAMTSSDGAKTRT"
     gene            complement(10001..10687)
                     /locus_tag="BKN51_RS31235"
                     /old_locus_tag="BKN51_30790"
     CDS             complement(10001..10687)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028561.1"
                     /locus_tag="BKN51_RS31235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30790"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_101611044.1"
                     /sec_met_domain="CDPS (E-value: 2.1e-77, bitscore: 258.6,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRPQPLTEHCTDPLARAEHVCIGVSPFNSYFTVDRIADLARWAM
                     SAFQGFHFFVPDGPSAFTLEALGYDPVRAAQKAQRQGNYTRNKIVRALQQVCPSDPHTL
                     ILDAAVLETDRAYLGLLSEAHQRFATDPEFSEQCLGATGWVLDRRLPEGEHPSRDQLRS
                     AVRYFLAELPMFVGTVAVAGVESSVFAYHQRVGFLERLYRGELSWRPLPGQGFVVLEQA
                     VPERAE"
     misc_feature    complement(10789..10802)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.98"
                     /tool="antismash"
     gene            10915..11841
                     /locus_tag="BKN51_RS31240"
                     /old_locus_tag="BKN51_30795"
     CDS             10915..11841
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632032.1"
                     /locus_tag="BKN51_RS31240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30795"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_233222929.1"
                     /transl_table=11
                     /translation="MICEIASSGSLNRAAAGLGLGQPALSHQLRRIERMVGGSLFHRDQ
                     HGVRPTELGSLILRRARAIVLTFDELELDFHRQEPEVGESVRIGWNDSAITGSLLGGLR
                     DLRPGEPFRTRADTSRTRLLAQVANRGIDLALIMICGGRGLPVPPEVRTMTLVREPSFV
                     AVPSGHPLADAEEIELTELAGEDWIVSSGGDGCRVVFREMCLAHGFDPRITHDVDIDTA
                     REDLVSGGYGVGLVQPTRPPSDGLVIRPLAGAPMCVRHVLAWREDGPCAPRVRELAGEA
                     TAGYWQLAERTAPYRTWLHRHGRLAAG"
     misc_feature    10924..10935
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            12079..12429
                     /locus_tag="BKN51_RS31245"
                     /old_locus_tag="BKN51_30800"
     CDS             12079..12429
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028559.1"
                     /locus_tag="BKN51_RS31245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30800"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_101611046.1"
                     /transl_table=11
                     /translation="MLPLISRTELLSRMEAGSVVVVDTMPAAYFEKEHLPEARNIPGFP
                     YEQAAEFTDHLAPTVLPDKTAAIVVYCANTPCRNSEFVGRRLLELGYTNVRKYREGIED
                     WVSNGLPTGSSS"
     misc_feature    12461..12476
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            12461..12901
                     /locus_tag="BKN51_RS31250"
                     /old_locus_tag="BKN51_30805"
     CDS             12461..12901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632034.1"
                     /locus_tag="BKN51_RS31250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30805"
                     /product="thioredoxin family protein"
                     /protein_id="WP_101611047.1"
                     /transl_table=11
                     /translation="MSKCKRFVCVLAGVLALITGFGSGVASAAPSPTAENVMVVTSANY
                     AEVMNISKQKLVIMDFGATWCPPCRQMKPVIERLAGEYGGKFLLGEVDVDRSRDLSSRY
                     NIQYLPTLVGVRNSAELPSSRNIGYPGEAKLRAWINAQLAKG"
     gene            complement(12919..13701)
                     /locus_tag="BKN51_RS31255"
                     /old_locus_tag="BKN51_30810"
     CDS             complement(12919..13701)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-116). E-value:
                     1.2e-21. Score: 69.4. Matches aSDomain:
                     nrpspksdomains_BKN51_RS31255_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020632035.1"
                     /locus_tag="BKN51_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30810"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_101611048.1"
                     /sec_met_domain="PF00561 (E-value: 7e-17, bitscore: 60.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-19, bitscore:
                     70.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGSLVVIQRDGLITFGGDGPPIVLLHGLMGRATTWWRVARRLEP
                     YGRVHGLDARGHGRGPRGGPWRTERFADDVAAVLKTFDEPAVLIGHSMGGLHAWVTAAT
                     HPGLVRAVVCEDFAPDQRGRTVDDWRGHFESWPVPFRSLAHVREFFGDTGDYFIECVEE
                     REDGYHLIASLPDLYEIAAEWGRRDFWEYVERLRCPLLAIEGERTAMPHGQQAELAARV
                     PGGLGRHIVVEGAGHVVHEEAPETYLGAVEAFLSDVIG"
     aSDomain        complement(13354..13641)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKN51_RS31255_Abhydrolase_1.1"
                     /evalue="1.20E-21"
                     /label="BKN51_RS31255_Abhydrolase_1.1"
                     /locus_tag="BKN51_RS31255"
                     /protein_end="116"
                     /protein_start="20"
                     /score="69.4"
                     /tool="antismash"
                     /translation="PPIVLLHGLMGRATTWWRVARRLEPYGRVHGLDARGHGRGPRGGP
                     WRTERFADDVAAVLKTFDEPAVLIGHSMGGLHAWVTAATHPGLVRAVVCED"
     CDS_motif       complement(13393..13449)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKN51_RS31255_0001"
                     /evalue="1.30E-04"
                     /label="NRPS-te1"
                     /locus_tag="BKN51_RS31255"
                     /protein_end="103"
                     /protein_start="84"
                     /score="14.5"
                     /tool="antismash"
                     /translation="PAVLIGHSMGGLHAWVTAA"
     misc_feature    complement(13687..13689)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13700..15142
                     /locus_tag="BKN51_RS31260"
                     /old_locus_tag="BKN51_30815"
     CDS             13700..15142
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028556.1"
                     /locus_tag="BKN51_RS31260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30815"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_335645053.1"
                     /transl_table=11
                     /translation="MRSRVPAAGLVLGVICALIIGCSADPPPAAPPPPPPMNPTPGAAG
                     AGDPYYPMDGNGGYDAVEYQVGITYDPAKGRLDGDTTVTAKATQDLNRYNLDLRGLTVQ
                     SVEVEGKPAKFAREGEFELVVTPAEPIRNGTTFRTKVVYGGDPSATPKAGGSENGWQKS
                     KDGGAFIVGEPHSASFWYPVNETPRDKAMFNLTARVPDGWTVISNGREIQKTSANGWST
                     TSWQERTPVAAYLTTVAIDKFTVDRMSLPDGTPLVNAYAPGAEDRRDTGRRLPEIIGFL
                     TSKFGPYPVDAAGGIYLDEDIHFSLETQTRPTYAKWADLITVVHETAHQWFGDSVTLNS
                     WSDICLNECLASYAQWLWQESRDGQNLDDRYRAALEIMRGSPDFWTPKLVGMGAGKEFH
                     GVYDKGILAIHALRRKIGEGAFARLLKEWPAAYRNANASWADFEAFTIKLSEQDLRPFF
                     DAWFHGTVIPPDAELLPGTLRG"
     misc_feature    13991..13993
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15164..16351)
                     /locus_tag="BKN51_RS31265"
                     /old_locus_tag="BKN51_30820"
     CDS             complement(15164..16351)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165347.1"
                     /locus_tag="BKN51_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30820"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_233222928.1"
                     /transl_table=11
                     /translation="MADTKILISGASVAGPALAFWLTRYGFDVTIVERAPSPRPGGQAV
                     DLRGTAREVARRMGLDDRIRAACTDTVGETHVDRKNRTKATLRADDFGGDGVLAEIEIL
                     RGDLTEVLYEATREQTEYVFGDRITALDERADGVDVTFASGTRRTFDVVIGADGLHSGV
                     RALAFGEESRFVRHLGSYLAFFTVPNRLGLRNWAIGFDDVGRSAGIRAIRDGGEAMAYF
                     GFASEKVDYDHRDIEAQKALVRGFAAGMEWEAPWLLERLDDAPDFYFDSCAQVVMESWS
                     RGRIGLLGDAAFCPSPLSGQGTSLAFVGAYVLAGELAADLDTGLKRYESVMREFVENTQ
                     AMGRANAETIFAKSRTALRMRYLMMRAMRLKPVAALASRKMRDVVNGIDLPDYRH"
     misc_feature    complement(16383..16397)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            16414..16722
                     /locus_tag="BKN51_RS31270"
                     /old_locus_tag="BKN51_30825"
     CDS             16414..16722
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084240.1"
                     /locus_tag="BKN51_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30825"
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_005165349.1"
                     /transl_table=11
                     /translation="MAVVKINAIEVPEGAGPELEKRFAARLHAVDNQPGFLGFELLRPV
                     SGESRYFVYTKWESEEAYQAWASGPAREAHAGERAKPVSSGANLLEFEVVQASKPGE"
     gene            16715..17527
                     /locus_tag="BKN51_RS31275"
                     /old_locus_tag="BKN51_30830"
     CDS             16715..17527
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337749.1"
                     /locus_tag="BKN51_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30830"
                     /product="Sir2 family NAD-dependent protein deacetylase"
                     /protein_id="WP_101611051.1"
                     /transl_table=11
                     /translation="MSELERAAELIDGAGALLVCAGAGMGVDSGLPDFRGDEGFWKAYP
                     PYERLGISFVELADPRHFAEDPELAWGFYGHRLALYRATVPHEGFRLLASWGSRKPGGV
                     RAFTSNVDGQFQKAGHQHVAEAHGSIHHLQCLSRCTTEIWPSDDVEVPVDEDTMRAPAP
                     LPSCPRCGGLARPNILMFGDYDWLGQRSQAQLDELTAWRRAHRDLVVVELGAGQAVPTV
                     RRYSELASAATGALVRINPREPQIRHGRGISLASNGLETLKALDALLS"
     gene            complement(17520..18356)
                     /locus_tag="BKN51_RS31280"
                     /old_locus_tag="BKN51_30835"
     CDS             complement(17520..18356)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007028552.1"
                     /locus_tag="BKN51_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30835"
                     /product="hypothetical protein"
                     /protein_id="WP_101611052.1"
                     /transl_table=11
                     /translation="MRKLWGLLALLPVAACVPGQLPPGDPAGALGFAARPGEGPSLARQ
                     DPAVEIERLFRPGTDRTPVALARAGRNVIGVGYREYTGEERSVPVAWVSADEGRGAREV
                     VLPQDRPGYWAPRAIAADGDQVLVAGALGADVRVWASGDAGATWTVSPVPVRSGESWLS
                     TVLRVDGKWLLAGGSSAGALVMTGGPGAWEPVSLGEGRILGGTADKAGKAVLFGDRTEW
                     NRSQTSNRSCAVVWASGGGWQRGELGCPAEGITTAVTLEDGRVLLASNRDLWIRPS"
     gene            complement(18382..19362)
                     /locus_tag="BKN51_RS31285"
                     /old_locus_tag="BKN51_30840"
     CDS             complement(18382..19362)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337750.1"
                     /locus_tag="BKN51_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30840"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_101611053.1"
                     /transl_table=11
                     /translation="MVIEERAVPRTRGSARGKLVSGLLIGAVVPFAVLTAMRLVGYDGN
                     TYTIAALALTPYAGIATLVLAVLALGLRRWWVAAVALVLTFAIAALVLPRAFANEQKAL
                     GGKHVRVLASNMLGGQADPARIVGYVKEHQVDVLSLTELTPEAITGLDRAGLFRLLPFH
                     VLHPAEWASGSGLVSKYPLTPLTLSGDSTYKQPSAGVDLGDGVRIEVVAVHPAAPMWDR
                     HAWVDEAKDLPYADAEHDIRILAGDFNASLDHSVFRELLTRGYVDAADQLGKALQGTWT
                     NGAVPPVPIDHVLADKRAAIADFKVLETPGSDHDAVYAEVVLPGK"
     gene            19544..20521
                     /locus_tag="BKN51_RS31290"
                     /old_locus_tag="BKN51_30845"
     CDS             19544..20521
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165355.1"
                     /locus_tag="BKN51_RS31290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_30845"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_101611054.1"
                     /transl_table=11
                     /translation="MTHAIRAEGLVKHYGETKALDGVDLEVPAGKVVGVLGPNGAGKTT
                     AVRILATLIRPDRGHASVFGHDVVKNPMAVRSMIGLTGQYASVDEDLSGTENLVLIGRL
                     LEFSRADAKKRAADLLERFELTDAAGRAIKTYSGGMRRRLDLAASLVGRPKVLYLDEPT
                     TGLDPHARNEVWAVVRTLVADGTTVLLTTQYLEEADQLADTITVFDRGLVVANGRADEL
                     KRRTGGQTLQVRPTALADLDAVERILAALTGVKPNRDNDTGLLTAPVADPVLLSTLVRK
                     LDEAGITADELALRLPSLDEVFLALTGKRPEESTKDTTPEGSLV"
ORIGIN
        1 gggctcgacg tcgaggtcga gcccggacca gagggtcctg gtgccgaacg cgaggctcgc
       61 cccgcggaca cggacgcacg cacgcgcctc ggcaggtacg gaggtcacta cttcagtgcc
      121 cccgccagcg cgtccaccga cttcgtcatc catgcaatgt agtcggtcac accctgggga
      181 agtgtttcgg tgacgtcgac gaccgcgatc ccggcgctct tggcgtcgcc gacgacctgc
      241 tgggtgaccg gggtggtggt ctgcgcgttg ttgatcagcg ccttgacctg cttgccggaa
      301 atcagctgct tgacctggtt gagcgcggcg gcgggcacgt cctgctcggc ttccacggcc
      361 tcggcgaagg cgggcggcgt cgcgtcggtg accttcgcgc tgtcgagcag gtagtgcgcg
      421 acgggctcgg tcgcgacgac cttgccgccc gaggctccca gcccggtgac cttcttcagc
      481 agttcctggg tcttgccctt gaacgcggtc gcgttggcgg tgaaggcgtc cttcgacgcg
      541 ggctggatct cgccgagctt cgcggcgacc tggtcggcga tcttctcgac gccgggcagg
      601 ctgtaccaga cgtgctcgtt ctcgttgccg gtcgcggcga tgtcgacggc gacgagcttc
      661 tgcgcgccgg cggcctggtc cgcgagcttc gagaagaact cgtcgtagcc gccgccgttg
      721 gacagggtca gcttcgcgtt cttcgcggcg atggcgtcgc tcgcggtggt ctcgtaggag
      781 tgcgggtcgg ccgaggggtc gtggatgatc gaggtgacct cgaccttgtc gccgccgacg
      841 gcggtcacga cgctgcccca gacgtcggtc gaggcgacga ccttgatctt ctcgccgcca
      901 cccgggttcg cggcggcggc gttctgcgaa ccggacgccg tcgacgcctt gtcgccggac
      961 gcgcaagccg tcgcgccgag cgcgaggacg gccagggccg acacggccgc gaaaacactc
     1021 ttagtacggc gggaattcat ttactgcact cctgcggatg cccaggccag gtgtcccaga
     1081 tgccgggtaa tggaaaccgt tgtcagattc aactgtaccc catccggctg atggcacccc
     1141 ctgtccaggt acgagctgta cccagggtca ctctgaatcg agacctgcca cacgtcgggt
     1201 gatgcttctg caaaacgttc tgaaccgtta cggtttgcgg atgggccgtc ctatccgcac
     1261 caggaggcag gcgacactgg cgtcgttggc cgcagagctc ggtgtgtcga ggaccaccgt
     1321 ctccaatgcc tacaaccgac cggaccagtt gtcccctgag ctgcgccgac gcgtcctcga
     1381 gaccgcgcgc cgcctcggct acccgggccc ggacccggtg gcccgatcac tgcgaacgcg
     1441 caaggcgggt gctgtcggtc ttttgctcac cgagaacctc tcctacgctt tccgcgaccc
     1501 ggccgccatc ggcgtgctcg aagggctcgc gctggcgtgc gaggacgcgg gcgtcggcct
     1561 gcacctggtc ccggccagcc cgggccgcga ggacgtcgcg gccgtgcacc gcgcgggcgt
     1621 cgacggcttc gtcgtctatt ccgtgcccga cgacgacccg catctgggcg ccgtgctgga
     1681 gcgcccggtg ccgacggtga tcgtcgacca gccgcgcgtg gacggcgtcg accgggtcgg
     1741 cccggacgac gcggccgcgg tcaccgccat ggcgcagcac ctcatctcgc tgggccaccg
     1801 gcagatcggc gtgctgtgca tgcggctggg ccgcgagcgc aacgacgact tcgtctccat
     1861 ccagcggcag agcgccgcgc acttccacgt gcagcggatc cggctggagg cgctggccgc
     1921 cgcgttctcc gcggccggtg tcgactggtc gaccgtgccg gtggtcgaac gcttcgacca
     1981 caccgtggac gacggcgcgt cggccgcgcg ccagctgctc gacgcgtatc cgcaggtcac
     2041 cgccgtgatc tgcacttcgg acatcctcgc gctcggcgcg ctggccgagg cggaacgccg
     2101 tggactgcgg gtgccgcagg atctgacggt caccggtttc gacggcatca ccgaggccga
     2161 gcgatccggg ctcaccacgg tccaccagcc ggtactcgag aagggcaagg cggcgggcaa
     2221 gctgctgctc agctcggccg accgggtcgg gccgaaggtg atcaccctgc agaccgaact
     2281 gcgggtcggc cgcacgtcgg cgccgccacg aacggccgaa gaacgctggt tcgggccgtg
     2341 atgtagcccg taaagcgttg ctctcaccga gcgtgtccgt tcaaatggtc gtgtgacctc
     2401 aatagacgta cttctcaagc gaaaccagga gctgggcgac gtcactcctg gtgaccgttc
     2461 gtccccgagg ccctcactcc aggtggcggt tctgacctgc atggacgccc gtatccgggt
     2521 gttcgagatc ttcggcctgc tccagggcga atcccacgtc ctgcgcaacg ccggcggtgt
     2581 cgtcaccgac gacatgatcc gttcgctcgc gctgagccag cggaaactgg gcacgcgcga
     2641 ggtgctgatc gtccagcaca ccgaatgcgg cctgtccatg gtcaccgaag acgacttcaa
     2701 ggacgagctc gaagagagca ccggactgcg cccgacctgg gccgtcgagg cgttccgcga
     2761 ggtcgaggac agcgtgcgcc ggtcggtgca gcgcgtccgg cgcagcgact tccttccgca
     2821 ccgggacaac gtccgcggtt tcgtctacga cgtgaagaca gggcggttgt ccgaggtcgc
     2881 gtgagctgaa ggggactttc accgcatgcg acgcggtgaa agcgcccttc accacgtaag
     2941 acgaggagaa aggccccttc agccccaagg gtggccgcgc gggctcacct tttaagctgg
     3001 cagggtgggc gtcgacgcgg atgtgctgac cggatggttc gacgaagtgg ggcgcgatct
     3061 gccctggcgt gagccggaat gcaccgcctg gggtgtgctc gtcagcgaga tcatgttgca
     3121 gcagacgccg gtcgcgcggg tccagccgat ctggctcgaa tggatggcgc gctggccggt
     3181 gccgtcggcg ctggcggcgt cgtcccaggg cgaggtcgtg cgcgcctggg gcaaactcgg
     3241 ctatccgcgc cgcgcgttgc ggctgcacgc ggcggcggcc gtcatcgccg ccgaacacgg
     3301 tgacgtcgtt ccgtccgatg tggacactct gctcgcgttg cccggtatcg gcgcttacac
     3361 cgcgcgcgcg gtcgcggcct tcgcctacgg caagcgggca ccggtggtgg acacgaacgt
     3421 ccggcgcgtg gtggcgagag cggtgcacgg cgcgggtgac gccgggccgc cgtcgaacac
     3481 ccgcgacatg gccgacgtcg aggccctgct gccgaaggaa gacgcgcccg ccgcgaaact
     3541 ctcggcggcg ctgatggaac tcggcgcgct cgtctgcacc gcccgctcgc cgcgttgcgc
     3601 ggactgcccg atctacgacg actgcgcctg gcagcacgcg ggcaaacccg cctacgccgg
     3661 acccgcgaag caggtccaga agttcgcggg gaccgatcgc caggtgcggg ggctgttgct
     3721 cgacgtcctg cgcggaaccg aaggcccggt cgagaaggcg cggctcgatc tcgtctggga
     3781 cgaatccggg cagcgcgacc gttgcctcga ctccctgctg gtcgacggcc tgctcgaaca
     3841 gaccggcgac ggcctgttcg ccctccccgg ggaacactaa cgcattacga caaaagttgg
     3901 tcaatggttg tcaacgacgc gatggcgggt tagttttccg gccaacgcgc atgatgggag
     3961 ctacgcccgt ggccgacttc gaccgacgta ccgcgctcaa gggcggcctg acggtaagtg
     4021 ccgtcgggct actggggacg acaacgtttt ccgccgccgc cgtagcggcg cctggggcag
     4081 cagaaccgaa gatccatgac acggcggcct ggagcgcccg gcctccgaac gggacgatcg
     4141 aggtgcagaa ccacaagccg acgtacatcg tcgtgcacca cacggtcgat cccggcaacg
     4201 tcaccgacta ttcgctcgaa cacgccttct gggcgtcacg ggcgatccag aacttccaca
     4261 tggacacccg cggctgggtg gacagcggcc agcagttcac gaacagccgc ggcgggcaca
     4321 tcaccgaagg ccgccaccgc agcctggaag tgctgcgcgg cggcacgaag cacgtgctgg
     4381 gcgcgaacgt gggcaacaac aacagcacct gcatcgggat cgagaacgaa ggcctctaca
     4441 gcaccgagaa cgtcacaccg gcgctctggg actcgctggt gaagatggtc gcgtacatcg
     4501 cgtcgcagta cgggatctcg ccgcagttca tcaagggaca ccgggacttc aactcgaccg
     4561 aatgcccggg aaccgtgctg tacaaccggc ttccggagct gcgcaccgcc gtcggcggcc
     4621 tgctgggctc ggcgtcaccg aaggccgacc tgcccgagtg gccgttgctc aaacccggcg
     4681 acaccggacc gcgggtgcgg gtggcccagg aactcctgcg ggcacgtggt ttcgccgtcc
     4741 ccaccgacgg cctgttcgga cagtccacaa aggacgcggt cagcacgctg gcggcgaagc
     4801 acgggctgga gcgcgacctc tgcggcgcga cggcggcgac cgacgagacc gggttcctcg
     4861 gctccgacgt ctggccgctc atcgtagggc ccgggaccga tctgcgggcg ctgaaagcac
     4921 gactcgccgg ctgaacgcca gcggcaagag gatcacgaag gcggcgaccc aagggagcga
     4981 cgacgttccc agcggcagca gcagaccgcc gatgagcgcg cccccggcga cggcgccgtt
     5041 ccaggccgcg atggtgagcg actgggcggc gtcggccgtg gggcccgcga tcagcgcggt
     5101 caccgcctgg aacgcggtgg gcgcgccgcc gaacgccagc ccccacagcg cggcggcggt
     5161 cagcaccagg ccgtggacac cgtcgctgat ccccagcagg acgatggcgg cggccgtcgc
     5221 gccggtgcag aacatcagca cggcacgcgg atggcggtcg agcgcggtac ccaccacgac
     5281 cagcccgccg accgtcgcgc agccgaacac cagcagcgcc acgcccagca tccccgccac
     5341 gtccagcccg gcgagaaccg ggccgatgta ggtgtaggcc acgttgtgcc ccaaggagaa
     5401 cagcgccacc gtcgccagca cgggccgcat tccgggcagt ctggacgcgg ccagcggccg
     5461 ggtggacgcc gccggatccg cggggacggc gggcaccacg gccatcaccc acgccatcag
     5521 cggcacggtg atcagcgcca tcgcggcgaa ggcccagcgc cagtcggcca gttcgccgag
     5581 cgcggtaccg gcgggcacgc cgagggcgaa cccgatcggg gtgccggaca tggccacggc
     5641 cagcgcacgc ccggtgagtc ccggcggggc gagacgcatc gcgtaaccgg cgacgagaga
     5701 ccacatcacc ccggtcagcg cgccggagaa gatcctcgcg gccaggatca gcggatacga
     5761 cgaggacacg gcgatcagca ggttggtcac caggaaaccg gcgatcaaca gcaggagcaa
     5821 ccgtttgcgc gggacccgga gtgtcgcgct ggtgagcggg atggcggtca gcgcggtggt
     5881 gatcgcgtac accgtcacca gctgcccggt cgccgacggg gaaacgccca ggtcttcgga
     5941 catgcccagc agcagcccgg cgggcagcac ttcggtgagg cagccgagga agaccgtcgt
     6001 cgtcagcgcg agcagcgcgg ggatgggcag catgccccga cgatctcttc cccggtgcgg
     6061 cgcggggtag tcccgggcgg atatgccgtg gggttatcgg ccgggataac cccgtggcat
     6121 gcccggctga cagtgccgcg cgcggcgcgg gcgcacgcac gatggccggg catcctcccc
     6181 cgtagagaga aggctcgttc atgaccgtgc ggattcggtg gcaggagccc ttgtgcaccg
     6241 cgctgctcgc caccacgatg atcggcacct gccaggctcc ggccgcggct cagccggcac
     6301 ccggcagtga cgggtacgtg cacgtttcac ccgacggtac cgtcctcggc gccgatcctt
     6361 actacccgaa ggacggcaac ggcggttacg acgtcgacaa gtacgcgctc gcgctggact
     6421 actcgccgta ctcgatgctg ttgaacggca aggcgacgat caccgcgacg gccacccagg
     6481 acctcagccg gttcgacctc gacctgcgcg gcctcaccgt gcgctcggtg accgtcgacg
     6541 gggtgcccgc cgcgttccgg cgggcgggtg aacacgagct ggtgatcacc ccgcggaccc
     6601 cgctggccga aggcacccgg ttcaccgtgg tggtcggtta cgacgggcgc ccggagccga
     6661 tcggcacggc gcgtggccgc gtcggctggc tgggcacccc cggcgattcc gccgtcgcca
     6721 ccggccagcc gcgttcggca atgacctggt tccccgtcaa cggcaccgag gtcgacaaag
     6781 cgaccctgcg tgtctccgtc accgtcctgg acgaattctc cgtgctgggc aacggtttac
     6841 cggtctcaga cgtgcccgcc ggcttcggac ggcacaccgt cacctggtcg gaggacaccg
     6901 cactggcgcc gagcacggcg atgctcggca tcgggcgctg ggaggtcgag cggatcacgc
     6961 ttcccggtgg ccggaccgcg atcaacgcct accacccgtg cgccgtcgac aaacggaaga
     7021 tcggcggaca gctgcctgag gtgctggagt tcctcaccgg gaagttcggc gactacccgc
     7081 aatcggcggc gggcggactg ttcctcgacc gttctctcgg ttacacgcac ggcgcccaga
     7141 cccggccggt gtacggccgc acggccacca tcgccgatct ggtgtacgcc accgcgtacc
     7201 agtggtgggg agccggggtg agcggcaaga tgtggcgcga cacgctgatg cccgagtcga
     7261 tcgcgcagta cgcggtgtgg ctgtgggacg aggccaagaa cggcgtcgac ctcgaccggc
     7321 gctaccgcga aatggtcgcc aaggtgagcg gtgacaccgg tttctgggcg cccaagatca
     7381 ccgatccggg caagggaacc gaattcgcgc ccacgaccaa ggccgtgctg atggtgcacg
     7441 cgctgcgccg cacgatcggc gacgacgggt tcttccagat catggcgggc ttcccgatga
     7501 tcaacccgca gggcaaccag aactggcacg acttcgagct ctacgtctcc gcgatgaccc
     7561 agctcgatct cggcgcgttc aaccacgcgt ggctggacgg cacggtgcgg ccgccggacg
     7621 agctcctcta tcccgggccg ctgcgcccct cgcgatgaga acccccgccc ggacgacgtg
     7681 acccgatcat ccgtcgtccg ggcgggtccc caagtcaccg tgggactcca ggtatccggc
     7741 gtaaaccggg gccgtcctcg cctcggccca gtacgtttcg accacggcgg cgagcagttc
     7801 ctcccgtcgc cccgccacga aggtctcccg gttccaggcg agaacatgcc tgcgcggcaa
     7861 cacatccccg agcagaggcc gggtcacgac gccgaggttc cgcggatcgc agatcggctg
     7921 tgacaggccg atcgcgcccg cccggacgac catgagcgcc acctgctgcg aggtcacctg
     7981 atgggcgacc gacgggctga agccgtaccg cgcgcaggtg tcggcgaagt acttggtgaa
     8041 cgtggccgcc gaggaatccg acaccatcac ccaggattcg tcccgcagcg cacgcaggtc
     8101 gacgacctcc tcgcgggcca gcggatgtcc ttccggcagc aggacgaagg tcggctcggt
     8161 caccaccacc gcggtgtcca cactcgcggg gatttcgagc tcgtatcccg gatattcctt
     8221 gaccagcccc aattccgcgc gccgctgggc cagcaacggc agcagccgct cggggtggtc
     8281 gtcgtgcacg acctgtacct cggagacctc gggccacaac cggtgcacca gcgacggcag
     8341 atgcgcgacc agcgcgctgg ccacggacgc cacccggacg acgtcgggcg ggccgctggg
     8401 acagacgcgc tgctcgatgt cttcgagcag tttgtccagc tgtggcagca aagcggcggt
     8461 ccgccgcaac agcagctcgc ccatcggcgt cggtgtcacg ctgccttccc gccgatcgaa
     8521 caactgatag cccagcatgt tctccaaacg tttgagctgc gcggaaacgg cgggctgggt
     8581 gacgccgaga gcgatcgcgg cacgggaaag gctgcccgtg tccgcgatcg cccggatcac
     8641 ccgcaggtgg tgaacatcaa gctgtacgac gtcgaactcc tttgtcacgt acgggttttc
     8701 gccccgtcgg aagaagtcat cgccacggaa ccgcccgtga ccctggtccg tctgcccaga
     8761 agaacataca ggagaaaggc gccgaaaacg gaattcaccg tgggaattcc ccacggcagc
     8821 caggcaccca ccgtggcacc ggccacccag cagatcagcg cgacgggaac ccaggacggg
     8881 caagacgacg gcagttcccc ggacgcgcgg gtggcgtcca gatccggttt ccagcgccgg
     8941 accacgtagt actcggcgat caccactccg gccaccggtg gcgtgagcac gccgacccag
     9001 gtcaggaaag tggtgaaatg gtcgaggatg ccgatcgcgg agagcaccgt gccgagaccg
     9061 ccgagcagca gggtcgcggt ggtgcggtcg agccgccggg acagcagcac ctgcacggtg
     9121 ttcaccagcc cgagcgagga ggagtagagg ttccagtcgt tgatcttcag gatcgcggtg
     9181 accaggatca gcgtgccgag caccccggac gacgaggtga tgatcccgac cacgtcggcg
     9241 cttttcgccg cgtgcgcgag cagaaccccg atcaggccga tcaggtactg gccgagggtg
     9301 atgctgacca aggtctgttt caccacgtcg gacgcggtcc ggttgaaccg ggtcatgtcc
     9361 ggggtcatga tcgcgcccat gatgaacgcg cccgccacca gcgtggtgcc ctgcgcgagc
     9421 gacatcgccg gccccggcgg cggctcggcc atcaacgcgg gcagcgaatg gtcgtcgagt
     9481 gcggtgacga tcgaataccc tgccagcgcg aggaaagcgg gcaccgtcag gtacgccgtc
     9541 caggccatcg cgtggaagcc gaacacgacg atcgcggtga ccagcgcgcc gcccgcgagc
     9601 gcccacaccc agaccggcgg gccgcccatc aaggcgtgga ggccgtgggc gaacacgtcg
     9661 ttctgcaccc cgaaccagcc tgccaggctc agcgtcatga gcagcccgac cagcgaggac
     9721 ccgccggtgc cgaatccggt ccagcgcgcg agcaccgacg tggacagccc ttcccgggtg
     9781 ccggcgatgc ccatcaggat ggtgatgatc tccagcagta ccgaaccgat cgtgatggcc
     9841 agtaccgcgt tccagaaggt catgccgaac ccgagtaccg ccccgagcag gaactggtgg
     9901 aacgaggaga cctgcccgaa ccgttgcagc gcgacggaaa cccaggagta acggcgttcg
     9961 gcgggtaccc ggcgcaggga gaagtcgtcg tgttccacgg tcactccgcc cgttccggga
    10021 cggcttgttc gaggacgacg aatccctgac ccggcagtgg ccgccaggag agttcgccgc
    10081 ggtacagccg ttcgaggaac ccgacccgct ggtggtaggc gaaaacggag ctttcgaccc
    10141 cggcgaccgc gacggtgccg acgaacatcg gcaactcggc caggaagtac cggaccgcgc
    10201 tgcgcagctg gtcacggctg gggtgttcgc cttcgggcag ccgccggtcc agcacccagc
    10261 cggtggcgcc gaggcactgc tcggagaact ccgggtcggt ggcgaaccgc tggtgtgcct
    10321 cggaaagcag gccgaggtac gcgcgatcgg tttcgagcac cgcggcgtcc aggatcaggg
    10381 tgtgcggatc cgacgggcag acctgctgca acgcccggac gatcttgttg cgcgtgtagt
    10441 tgccttgccg ctgcgccttc tgcgccgcgc gaaccgggtc gtagccgagg gcttcgaggg
    10501 tgaacgcgga cggcccgtcc gggacgaaga aatgaaagcc ctgaaaggcc gacatggccc
    10561 agcgggcgag atcggcgatc cggtccacgg tgaaatagct gttgaacggg ctgacgccga
    10621 tgcaaacgtg ctcggcgcgc gccagcggat cggtacaatg ctcggtgagc ggctgtggtc
    10681 gcagcaagac ggctcctgat tcgcgtgata tgcgccggag ttgaggcgtc gaccgaacgt
    10741 agccacggcg ggtaatccgc ggtattgccg atcgtggctg tcatcgcgtt ataggaattc
    10801 gacgatcttt cgtgcctgcg ggacaacggt tgaatcgccg cgaccttcgg gggtgccgga
    10861 cgcgggcgga gcgcggtata cgaagtcatg gagattcagg ttcggcatct tcgcgtgatc
    10921 tgtgaaatcg cttcctcggg cagtctcaac cgtgccgcgg ccgggctggg gctcgggcag
    10981 cctgcgctca gccaccagtt gcgccggatc gagcggatgg tcggcggctc actgttccac
    11041 cgcgaccagc acggggtgcg gccgaccgaa ctcggttccc tgatcctgcg gcgggcgcgc
    11101 gcgatcgtgc tcaccttcga cgaactggag ctcgacttcc accgccagga accggaagtc
    11161 ggcgaatcgg tcagaatcgg ctggaacgac agcgccatca cgggttcgct gctcggcggg
    11221 ctgcgcgacc tgcgtccggg tgaaccgttc cgcacgcgcg cggacacctc ccgcacccgg
    11281 ctgctcgcgc aggtcgcgaa ccgcggcatc gacctcgcgc tgatcatgat ctgcggcggg
    11341 cgtgggctgc cggtgccgcc ggaggtgcgg accatgaccc tggtcaggga accgtcgttc
    11401 gtcgcggtcc cgtccgggca tccgctcgcc gacgccgagg agatcgaact caccgaactg
    11461 gcgggcgagg actggatcgt gtcgagcggg ggcgacggct gccgggtcgt gttccgcgaa
    11521 atgtgtctcg cgcacggttt cgaccccagg atcacccacg acgtggacat cgacaccgcg
    11581 cgggaagacc tggtcagcgg cggctacggc gtcggactgg tccagccgac ccggccgccg
    11641 tcggacggcc tggtcatccg gccgctggcg ggggcgccga tgtgcgtgcg gcacgtgctg
    11701 gcctggcggg aggacggccc gtgcgcgccc cgcgtccggg aactcgcggg cgaggcgacg
    11761 gcggggtact ggcagctggc cgaacggacg gcgccgtacc ggacctggct gcaccggcac
    11821 gggcggctgg ccgccggctg acggccgcgg cgcccggctg gcggggcgcg ttctggtcgc
    11881 gggtggcgtg ctccgtgaag gcctccttgc ctaccttgag ggtagggaag gaggccttca
    11941 cggaccttcg cgatcgccca tcgcgcaggc cccttcccct cgataaccct ccggcatgtc
    12001 gaggcggcac tagagcgcgt cccggcagac ggccgacgat gggaatcgtc aatcacggtc
    12061 gtgaagagaa ggggcaccat gctgccgttg atctctcgta cggaactgct ctcccgaatg
    12121 gaggccgggt ctgtggtggt ggtcgacacg atgccggccg cctatttcga aaaggagcat
    12181 ctcccggaag cgcgcaacat tccgggattc ccgtacgaac aggccgccga attcaccgat
    12241 cacctggcac cgacggtgct cccggacaag accgccgcga tcgtcgtcta ttgcgcgaac
    12301 acgccgtgcc gcaacagtga attcgtcgga cggcggctgc tggagctcgg gtacacgaac
    12361 gtccgcaagt accgcgaagg catcgaagac tgggtctcga acggtttgcc gaccggttct
    12421 tcgtcctgag tggacacacc ccgcatctaa ggagaacgtc ttgtccaaat gcaaacgatt
    12481 cgtctgcgtg ctggccggcg tgctggcgct catcaccggt ttcggctccg gcgtcgcttc
    12541 ggccgcgccg tcaccgacgg ccgagaacgt gatggtggtg acgtccgcca actacgccga
    12601 ggtcatgaac atctcgaagc agaagctggt catcatggac ttcggcgcga cctggtgccc
    12661 gccgtgccgc cagatgaagc cggtcatcga acggctcgcc ggtgagtacg gcggcaagtt
    12721 cctgctcggc gaggtcgacg tcgaccgcag ccgggacctc tccagccggt acaacatcca
    12781 gtatctcccg acgctggtcg gggtccgcaa cagcgcggaa ctgccgtcct cccggaacat
    12841 cggctacccc ggcgaagcga agctgcgcgc ctggatcaac gctcagttgg cgaagggctg
    12901 agcgtgtggc tccggggcct acccgatgac gtcggagaga aacgcttcga cggcacctag
    12961 gtaggtctcc ggggcctctt cgtgcacgac gtgcccggcg ccctcgacga cgatgtgacg
    13021 gccgaggccg ccgggcacgc gggccgcgag ttcggcctgc tgcccgtgcg gcatcgccgt
    13081 ccgttcgcct tcgatcgcca gcagcgggca tcggaggcgt tcgacgtact cccagaaatc
    13141 ccgccgtccc cattccgccg cgatctcgta cagatcgggg agcgaggcga tcaggtgata
    13201 accgtcttcg cgttcttcga cgcattcgat gaaatagtcg ccggtgtcgc cgaagaattc
    13261 gcgcacgtgg gccagtgacc ggaacgggac cggccaggat tcgaagtggc cgcgccagtc
    13321 gtcgacggtc cgcccgcgct ggtccggcgc gaagtcctcg cagaccaccg cgcggacgag
    13381 gccgggatgc gtcgccgcgg tgacccacgc gtgcaggccg cccatcgaat gtccgatcag
    13441 gaccgcgggc tcgtcgaagg tcttcaggac cgcggcgacg tcgtcggcga accgctcggt
    13501 gcgccagggg ccgccacgtg gtccgcgtcc gtgcccgcgc gcgtcgagac cgtggacacg
    13561 cccgtacggt tcgagccttc gcgcgacccg ccaccacgtc gtggccctgc ccatcagccc
    13621 gtgcaggagg acgatcggcg gcccgtcacc gccgaaagtg atcaacccgt cgcgctgaat
    13681 caccactaag ctcccctcca tgcgcagccg tgtccccgcc gccggtctgg tcctgggggt
    13741 catctgcgcc ctgattatcg ggtgcagtgc cgatcctccc ccggcggcgc ccccaccacc
    13801 gccgccgatg aatccgacgc cgggtgccgc gggcgcgggt gatccgtact acccgatgga
    13861 cggaaacggc ggttacgacg cggtcgaata ccaggtcgga atcacttacg accccgcgaa
    13921 agggcgtctc gacggcgaca ccacggtgac cgcgaaagcg acccaagacc tcaatcggta
    13981 caacttggac ttacgcggct tgactgtcca atccgttgaa gtggagggaa aaccggcgaa
    14041 gttcgcccgg gagggcgaat tcgagctggt ggtgacgccc gccgaaccga tccggaacgg
    14101 gaccaccttc cgcacgaagg tcgtctacgg cggcgaccct tcggcgaccc ccaaggcggg
    14161 cggcagcgag aacggctggc agaagtcgaa ggacggcggc gcgttcatcg tcggcgagcc
    14221 gcattcggcg tcgttctggt atcccgtcaa cgaaaccccg cgcgacaagg cgatgttcaa
    14281 cctcaccgcc cgggtgccgg acggctggac cgtcatctcg aacggccgcg agatccagaa
    14341 gacctcggcg aacggctggt ccacgacgtc ctggcaggag cgcacgcccg tggcggccta
    14401 cctgaccacg gtggcgatcg acaagttcac cgtcgaccgg atgtcgctcc cggacgggac
    14461 gccgctggtc aacgcgtacg cgccgggcgc ggaggaccgg cgcgacaccg gcaggcggct
    14521 gccggagatc atcggcttcc tgacctcgaa gttcgggccg tacccggtgg acgcggcggg
    14581 cgggatctac ctcgacgagg acatccactt ctcgctggag acccagacca ggccgactta
    14641 cgcgaaatgg gccgacctga tcaccgtggt gcacgaaacc gcacaccagt ggttcggcga
    14701 ttcggtgacg ctgaattcgt ggtccgacat ctgcctgaac gaatgtctcg cgtcgtacgc
    14761 gcaatggctg tggcaggaat cgcgggacgg ccagaacctc gacgaccgct atcgcgccgc
    14821 cctcgagatc atgcggggca gcccggattt ctggacgccg aaactggtcg gcatgggggc
    14881 gggaaaggaa ttccacggcg tctacgacaa ggggatcctc gccatccacg cgctgcggcg
    14941 caagatcggc gaaggcgcgt tcgcgcggct gctgaaggaa tggccggcgg cgtaccggaa
    15001 cgccaacgcg tcctgggcgg acttcgaggc gttcacgatc aagctctcgg agcaggatct
    15061 gcggccgttc ttcgacgcct ggttccacgg cacggtgatc ccgccggacg ccgaactgct
    15121 gccgggcacc ctgcggggct aggcacctgt cgcaagtagt cctctagtgg cggtagtcgg
    15181 gcaggtcgat cccgttcacc acgtcccgca tcttccgtga cgccagcgcg gcgaccggtt
    15241 tgagccgcat cgcccgcatc atcaggtacc tcatccgcag ggccgtccgc gacttcgcga
    15301 agatcgtctc ggcgttggcc cgccccatcg cctgcgtgtt ctcgacgaac tcgcgcatca
    15361 ccgactcgta ccgcttgagg ccggtgtcga ggtcggcggc gagttccccg gcgaggacgt
    15421 acgcgccgac gaacgccagg ctcgtgccct gtccggagag cggcgacggg cagaacgcgg
    15481 cgtcgcccag cagcccgatc cggccgcgcg accacgattc catgaccacc tgggcgcacg
    15541 agtcgaagta gaagtcgggg gcgtcgtcca gccgttccag cagccagggc gcctcccatt
    15601 ccatcccggc ggcgaacccg cggaccagcg ccttctgcgc ctcgatgtcg cggtggtcgt
    15661 agtcgacctt ctccgaggcg aacccgaagt aggccatcgc ctcgccaccg tcgcgaatcg
    15721 cgcggatccc ggcggaccgg ccgacgtcgt cgaagccgat cgcccagttc cgcaggccca
    15781 gccggttcgg cacggtgaag aacgccaggt acgagcccag atgccggacg aaccgggact
    15841 cttcgccgaa ggccagcgcc cgcactccgg agtgcagccc gtccgccccg atgaccacgt
    15901 cgaacgtcct ccgcgtacca ctggcgaagg tgacatcgac gccgtcggcc cgctcgtcca
    15961 gcgcggtgat ccggtcgccg aagacgtatt ccgtctgctc cctggtcgcc tcgtacagca
    16021 cctcggtcag gtcgccgcgg aggatctcga tctcggcgag gaccccgtcg ccgccgaagt
    16081 cgtcggcgcg gagggtggcc ttcgtccggt tcttccggtc gacgtgcgtc tcgccaacgg
    16141 tgtccgtgca cgccgcgcgg atgcggtcgt ccaggcccat gcggcgggcg acctccctgg
    16201 ccgttccgcg caggtcgacg gcctgaccgc cggggcgcgg cgaaggcgcg cgctccacga
    16261 tggtcacgtc gaatccgtac cgcgtcagcc agaacgccag cgcggggccc gcgacgctcg
    16321 cgccggagat gaggatcttc gtgtcggcca ttccccggaa ggtcccacgc atcacatcgc
    16381 ggcgcaaaag agtttcaccg tagggtggac ggcatggctg tcgtgaagat caacgcgatc
    16441 gaggtccccg agggcgcagg ccccgagctg gagaagcggt tcgccgcacg gctgcacgcc
    16501 gtcgacaacc agcccggctt cctcggcttc gaactgctcc gcccggtctc cggcgaaagc
    16561 cgctacttcg tctacacgaa gtgggagtcc gaagaggcgt accaggcgtg ggcgtccggc
    16621 ccggcgcgtg aggcgcacgc gggcgaacgc gcgaagccgg tctccagcgg ggcgaacctg
    16681 ctggaattcg aggtcgtcca ggcttcgaag ccgggtgagt gagctcgaac gagccgcgga
    16741 actgatcgac ggcgccggcg cgctgctcgt ctgcgccggc gccggcatgg gcgtcgactc
    16801 cggcctgccc gatttccggg gcgacgaggg tttctggaag gcgtatccgc cgtacgagcg
    16861 gctggggatc agcttcgtcg aactcgccga cccgcggcat ttcgccgaag atcccgagct
    16921 ggcctggggt ttctacgggc accggctcgc gctgtaccgc gccaccgtcc cgcacgaggg
    16981 attccggctg ctggcgtctt ggggctcgcg caaacccggc ggcgtgcgcg cgttcacgtc
    17041 caatgtggac ggtcagttcc agaaggccgg ccatcagcac gtggccgagg cgcacgggtc
    17101 gatccatcac ctgcagtgcc tttcccggtg caccaccgag atctggccgt cggacgacgt
    17161 cgaggtcccg gtcgacgagg acacgatgcg cgccccggcc ccgctgccgt cgtgcccgcg
    17221 ctgcggcggc ctcgcgcgcc ccaacatcct gatgttcggt gactacgact ggctcgggca
    17281 gcgcagccag gcccagctcg acgagctgac cgcgtggcgc cgcgcgcatc gcgatctcgt
    17341 ggtggtggaa ctcggcgccg ggcaggccgt gccgaccgtg cggcgctact cggagctggc
    17401 cagtgccgcg accggcgccc tggtccggat caacccgcgc gaacctcaga tccggcacgg
    17461 ccgcggcatc tcactcgcga gcaacggcct cgaaaccctc aaggcgctgg acgccctgct
    17521 cagctaggcc ggatccacag atcccggttg ctcgccagca gcacccgccc gtcttcgagg
    17581 gtcaccgcgg tggtgatccc ctcggccggg cagcccagct cacctcgctg ccagccgccg
    17641 ccggacgccc acaccaccgc acaggaccgg ttcgacgtct gggaccggtt ccactcggtc
    17701 cggtccccga agagcaccgc cttgcccgcc ttgtcggccg tcccgccgag gatccggccc
    17761 tcgccgagcg aaacgggctc ccaggcgccg ggtccaccgg tcatgaccag tgctccggcc
    17821 gaggaacccc cggccagcag ccatttcccg tccacccgga gcacggtgga gagccagctc
    17881 tcgcccgagc gcactggaac cggcgacacc gtccaggtcg cgcccgcgtc accggaggcc
    17941 cacacccgca cgtccgcgcc gagggcaccg gcgacgagga cctgatcgcc gtcggccgcg
    18001 atcgccctcg gcgcccagta ccccggcctg tcctgcggca acacgacctc acgcgcgccg
    18061 cgcccctcat ccgcggacac ccaggcgacc ggaaccgacc gttcctcgcc ggtgtactcc
    18121 cggtacccga caccgatgac gttccggccc gccctggcca gcgccaccgg tgtccggtcg
    18181 gtacccggcc ggaacagccg ttcgatctcg acggcggggt cctgacgggc gagggacggt
    18241 ccctcgccgg gccgggcggc gaagcccagc gcgccggccg gatcacccgg cggcagctgt
    18301 cccggcacac aggccgcgac cggcagcagc gcgagaagtc cccagagctt cctcatgagc
    18361 ggggagcttt ccagcgggag gtcactttcc gggcagcacg acctcggcgt acacggcatc
    18421 gtgatcgctg ccgggcgtct ccagcacctt gaagtccgcg atggccgccc gtttgtccgc
    18481 cagcacgtgg tcgatcggca ccggcggcac cgccccgttc gtccaggtcc cctgcagcgc
    18541 cttccccagc tgatcggccg cgtccacgta tcccctggtc agcagctcac ggaagaccga
    18601 gtggtcgagg ctggcgttga agtcgcccgc caggatccgg atgtcgtgct ccgcgtcggc
    18661 gtacggcaga tccttggcct cgtcgaccca cgcgtgcctg tcccacatcg gcgccgccgg
    18721 atgcaccgcg acgacctcga tccggacacc gtcgccgagg tccacgcccg cactgggttg
    18781 tttgtaggtc gagtcgccgc tcagcgtcag cggcgtcagc gggtacttcg acaccagccc
    18841 ggagccagac gcccactccg ccggatgcag cacgtggaac ggcaggagcc ggaacaaccc
    18901 ggcccggtcg agcccggtga tcgcctcggg cgtcagctcg gtcaggctca ggacgtcgac
    18961 ctggtgttcc ttcacgtaac cgacgatcct ggccggatcc gcctgtccgc cgagcatgtt
    19021 cgacgcgagc acgcggacgt gcttcccgcc gagcgccttc tgctcgttcg cgaacgcgcg
    19081 gggcagcacc agcgcggcga tcgcgaaggt caggaccagg gcgacggccg cgacccacca
    19141 gcggcggagt cccagcgcga gaacggcgag caccagcgtc gcgatcccgg cgtacggcgt
    19201 cagcgcgagc gccgcgatcg tgtacgtgtt gccgtcgtag cccaccagcc gcatcgccgt
    19261 cagcaccgcg aacggcacga ccgccccgat gagcagcccg ctgaccagct tcccccgggc
    19321 actcccgcgg gtccggggaa ccgcccgttc ttcgatcacc atgacatcga gtatgccgat
    19381 cgacgcccga tgtggcggcg gtctccacaa cacctccaca acctcctcac gccgcggcta
    19441 ccagcgctta tcaggttttg ccagccgctg tcagcccgct gtgcgcggcc tgccaggcgg
    19501 agcgggcacc tttgtccgcg gggcgagatc cacaggagga aacatgacgc acgcgatcag
    19561 ggccgagggc ctggtcaagc actatgggga gacgaaggca ctcgacgggg tcgatctgga
    19621 ggtcccggcg ggcaaggtgg tcggggtgct ggggccgaac ggcgcgggga agacgaccgc
    19681 cgtccggatc ctggccacct tgatccggcc ggaccgcggc cacgcgagcg tcttcggtca
    19741 cgacgtcgtc aagaacccga tggcggtccg cagcatgatc gggctgaccg ggcagtacgc
    19801 gtcggtcgac gaggatctct ccggcacgga gaacctcgtg ctgatcggca ggctgctgga
    19861 gttctccagg gcggacgcga agaagcgcgc ggccgatctg ctggagcggt tcgagctgac
    19921 cgacgccgcc ggacgcgcga tcaagaccta ctcgggcggg atgcgacggc ggctcgacct
    19981 cgccgcgagc ctggtcggcc gtccgaaggt gctctacctg gacgagccga ccaccggact
    20041 cgacccgcac gcccgcaacg aggtctgggc cgtggtccgg acgctggtcg cggacgggac
    20101 gacggtgctg ctcaccacgc agtacctgga ggaggccgac cagctggccg acacgatcac
    20161 cgtgttcgac cgcgggctgg tcgtggcgaa cgggcgggcc gacgagctca agcgccggac
    20221 cggcggccag acgctgcaag tccggccgac cgcgctcgcc gatctcgacg ccgtcgagcg
    20281 catcctggcc gcgctcaccg gggtcaagcc gaaccgggac aacgacaccg ggctgctcac
    20341 cgcgcccgtc gccgaccccg tcctgctgtc caccttggtc cgcaaactgg acgaagccgg
    20401 gatcaccgcg gacgaactgg cgctgcggct gcccagcctc gacgaggtgt tcctcgcgct
    20461 caccggcaag cgacccgaag agtccacaaa ggacacgact ccggaaggga gcctggtatg
    20521 acgaccatcg cagtgcccgc ggcaccacgg cacgtttccc tctccagcag cgtccagcac
    20581 gggctttccc ttgcctggcg cggcatcctg aagatccgca agaacccgga acagctggcc
    20641 gacgtcacca tcgcgccgat catcttcctg gtcatgttcg tctacct
//
