LOCUS       NZ_CP017780            21029 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Amycolatopsis sp. BJA-103 chromosome, complete genome.
ACCESSION   NZ_CP017780
VERSION     NZ_CP017780.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. BJA-103
  ORGANISM  Amycolatopsis sp. BJA-103
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Isolation and identification of a potent feather degrading rare
            actinomycete Amycolatosis sp. BJA-103 isolated from the rhizomes of
            Valeriana jatamansi Jones with abundant antibiotic biosynthetic
            potential
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:58:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,631
            CDSs (total)                      :: 8,562
            Genes (coding)                    :: 8,496
            CDSs (with protein)               :: 8,496
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 31 of 66
            Pseudo Genes (incomplete)         :: 47 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 13 of 66
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:43:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4997152
            Orig. end                         :: 5018181
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017780.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from B415, College of Life
            Sciences, Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21029
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="23"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21029
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21029
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11029](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(12..25)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.4"
                     /tool="antismash"
     gene            complement(535..1011)
                     /locus_tag="BKN51_RS21520"
                     /old_locus_tag="BKN51_21165"
     CDS             complement(535..1011)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019846.4"
                     /locus_tag="BKN51_RS21520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21165"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_233223649.1"
                     /transl_table=11
                     /translation="MKSLFRAGLRRPTDSVVGVDLSPEMADEARRRSPEADFRVGDAYA
                     LPVDGGVRGVPGGQGFHELAEPELALAEARRVLVPGGRIVLSGHEWEALVIDSVHPALT
                     REIVRARASAITAPRAARGFRRLLAGSGVREVSVEGVVGFLDREAYWLEGAVFG"
     gene            complement(1073..1648)
                     /locus_tag="BKN51_RS21525"
                     /old_locus_tag="BKN51_21170"
     CDS             complement(1073..1648)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155034.1"
                     /locus_tag="BKN51_RS21525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21170"
                     /product="DUF305 domain-containing protein"
                     /protein_id="WP_101609336.1"
                     /transl_table=11
                     /translation="MTSRKLVGAALAALASFVVLTGCASSDTASSGHAMSTMNVPNPQQ
                     AGHNEADVTFAQGMIPHHEQALSMAKLVDGRTRNAKIVDLAARIQKAQDPEIQQLTGLL
                     KGWGVTPSGGHSGHGMMADDDLAELGKAKDAAFDKQWLEMMVKHHEGALAMAKTALRQG
                     GDAEVKALAQKVIDGQQAEITEMRALLG"
     gene            complement(1697..2068)
                     /locus_tag="BKN51_RS21530"
                     /old_locus_tag="BKN51_21175"
     CDS             complement(1697..2068)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155037.1"
                     /locus_tag="BKN51_RS21530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21175"
                     /product="DUF6153 family protein"
                     /protein_id="WP_101609337.1"
                     /transl_table=11
                     /translation="MTQSSYPAALRWLLLCVVALGLVGMHHVIAETGHGAGHSAVAMAD
                     PCCEDTPSHDDGGHSGLHLCLAVLAAAALLIVTWLLVRSGRTMATWSSRPGGGAAPGRD
                     PPRWRPVPQRLSFLCVLRV"
     gene            complement(2088..2459)
                     /locus_tag="BKN51_RS21535"
                     /old_locus_tag="BKN51_21180"
     CDS             complement(2088..2459)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030039.1"
                     /locus_tag="BKN51_RS21535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21180"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_007030039.1"
                     /transl_table=11
                     /translation="MHESVPDFEMPTEEQVHLAAETFRLLADPTRIKVLWALLQGESSV
                     ACLAELAGAAPTAVSQHLAKLRLAGLVKGRREGTFVYYSAANDHVRGLLAQALFHADHI
                     DRDIPALHSAGKPHRPAAR"
     gene            2535..3521
                     /locus_tag="BKN51_RS21540"
                     /old_locus_tag="BKN51_21185"
     CDS             2535..3521
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630218.1"
                     /locus_tag="BKN51_RS21540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21185"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_174720437.1"
                     /transl_table=11
                     /translation="MTGHGHSHGHKPGKSRLRHLLTPHSHDSADRVDTALETSKRGVRT
                     LIWSFAALFVTAVAQLALVLVTGSVALLGDTIHNFADALTAVPLGIAFLLGRRAATRRY
                     TYGLGRAEDLAGVLVVLLIAASAVLAGYESIERLLDPRPVRHLWVVAAAGVIGFAGNEL
                     VARYRITVGREIGSAALVADGLHARTDGFTSLAVVLGAVGVGFGFPLADPIIGLAITVA
                     ILFVLRDAAKEVFRRLMDAVDPADVDRAERAAAEVPGVLGTRDLRMRWIGHSLRAELAI
                     SVGAELTVTEAHHLAHLVERRLRQVLPRLAEAVVHTEPAHAHEIVSG"
     misc_feature    2748..2750
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3518..4564
                     /locus_tag="BKN51_RS21545"
                     /old_locus_tag="BKN51_21190"
     CDS             3518..4564
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630219.1"
                     /locus_tag="BKN51_RS21545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21190"
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="WP_101609338.1"
                     /transl_table=11
                     /translation="MTLSDNDIRAVRARAQRLDSPAGDLLAVARSLAAIQAQSSPAARL
                     AVRVRSRGLIAPDVDASREVARTWLMRKTLHLVPAADLRWLNRLFGPRNAQSGQGRRTQ
                     LGLTGELCERALKHLQDLLRGKALTRREILDGLASDGITLDAKSQAPAHLLAYAANRGL
                     LCRGQDVGSEPTYVLLDEWITEDDTPDDPRAELARRYLTAYGIATAEDFGAWSGFPLGL
                     CREAFDALDLVPAGSGFALAETELTAPPCPPRLLGAFDTYLLGYRDRDLLLDPAEAKRV
                     NSGGGMIAPTVLVDGRIAGTWHAERTAKQTKVVIEPFAALSRSAVTGLESEVDDYGRFL
                     GEAAVLVI"
     gene            complement(4557..5714)
                     /locus_tag="BKN51_RS21550"
                     /old_locus_tag="BKN51_21195"
     CDS             complement(4557..5714)
                     /NRPS_PKS="Domain: Abhydrolase_1 (96-219). E-value:
                     5.6e-12. Score: 37.7. Matches aSDomain:
                     nrpspksdomains_BKN51_RS21550_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335875.1"
                     /locus_tag="BKN51_RS21550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21195"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_101609339.1"
                     /sec_met_domain="PF00561 (E-value: 4.3e-07, bitscore: 28.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTEIRPFLLDVPQEQLDELRAKLDSARWPAPLPGDGWDTGVPV
                     SWLRGLAEYWRDGYDWRAAEREINRFPQFTTEIDGQNIHFLHVRSPEAGATPLILTHGW
                     PGSVVEFLDVIGPLTDPKAHGGESGDAFHLVIPSLPGFGFSGPVSDSGWTMPRIGRAWA
                     ELMRRLGYERYGVQGGDLGASVSPEVGRVAPDKVIGVHVNGGLSPMPPMSLPEEELASL
                     TDIERDRITRIEAFMQEEFGYISIQSTRPQTLGYGLIDSPVAQLAWIMDKFREWTHPRP
                     TLPEEIIGRDRLLTNVMFTWLTGTAASSAYVGYAQAETWGAVEKNSGVPTAVLIFAHDV
                     GIRRYSEDAHTIVRWTDVDRGGHFAALEEPEILVADVREFFRSLK"
     aSDomain        complement(5058..5426)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKN51_RS21550_Abhydrolase_1.1"
                     /evalue="5.60E-12"
                     /label="BKN51_RS21550_Abhydrolase_1.1"
                     /locus_tag="BKN51_RS21550"
                     /protein_end="219"
                     /protein_start="96"
                     /score="37.7"
                     /tool="antismash"
                     /translation="PLILTHGWPGSVVEFLDVIGPLTDPKAHGGESGDAFHLVIPSLPG
                     FGFSGPVSDSGWTMPRIGRAWAELMRRLGYERYGVQGGDLGASVSPEVGRVAPDKVIGV
                     HVNGGLSPMPPMSLPEEEL"
     gene            5793..6185
                     /locus_tag="BKN51_RS21555"
                     /old_locus_tag="BKN51_21200"
     CDS             5793..6185
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030035.1"
                     /locus_tag="BKN51_RS21555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21200"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_101609340.1"
                     /transl_table=11
                     /translation="MKDKYLAYGRLIRDGKILFIRRRPGSFLGGHWELPGGTVEPGERQ
                     AETVVREFAEETGLTVRVTGENGAHSWDDVEGRPMRIHATVFSLAEEEPREVVLDPEEH
                     DAFTWYTREEAAGLDLAEHFRRAIED"
     gene            complement(6513..7808)
                     /locus_tag="BKN51_RS21560"
                     /old_locus_tag="BKN51_21205"
     CDS             complement(6513..7808)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155047.1"
                     /locus_tag="BKN51_RS21560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21205"
                     /product="MFS transporter"
                     /protein_id="WP_101609341.1"
                     /transl_table=11
                     /translation="MESTKRLALAQLISSVGDGAYYVSSALYFTLIVGLSPAHVGLGLT
                     VGWAVGSVAGVALGQLADRRGPKGTAVVLGLGTAASVTAFLFVNSVVAFVIAACVYACF
                     QCGLGAARQALLAGLIDPAGRTTFRARLQAMSNAGIALGAALGGIALALGTREAFLTVF
                     VIDALSFVTAALVLRKLPSVAPAPVRTGEPSVAVLRDRPYALLALLNMIMLLYMPLFSL
                     VLPLWISTRTAAPGWLVSAMLVLNTASVVVFQVRVARGVTGLRSASRYARYAGSLLFVS
                     CLVFSFSAMSASAWTAALVLLAGAALQVVGEMAQAAGSWEIGFGLAPEGRQGQYQGLFG
                     AGTAIARMLGPVLLTSLILVGGEAGWVVLGGLFLLVGALTAPAVRWAERSSQRFDPENG
                     GAVTDAQQVDREVVVGDAAARPERGLEVGALG"
     gene            7889..9316
                     /locus_tag="BKN51_RS21565"
                     /old_locus_tag="BKN51_21210"
     CDS             7889..9316
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (149-414). E-value: 9e-21.
                     Score: 66.3. Matches aSDomain:
                     nrpspksdomains_BKN51_RS21565_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630223.1"
                     /locus_tag="BKN51_RS21565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21210"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_101609342.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.4e-18, bitscore:
                     66.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFHISLDGHTDLAARIYRQLRDGILDGRLRSGERLPPTRELARE
                     LDVSRNTVAVAYERLTAEGFLSSHVGRGTFVSADPVGRADRAAPSGAGVLPSAHWRSLP
                     APLGADRSTPAFDFRVGVPDPALFPLSTWRRLVSQALRPSLLPPSGYADPAGLEGLRVA
                     IARHIGAARSVRASGEDVLVTQGAQQALDLIGRVLIEPGTRVAVEDPGYPPAERLFAAL
                     GARVVKVPVDAEGLDVTALAPGIRLIYTTPSHQFPLGTPMSLSRRTALLAWAERHDAVI
                     VEDDYDSEYRFSDRPLEPLQSLDRDGRVLYVGSFSKTLLPLLRLGFLVAPASLRPALRQ
                     AKQLMDWHGDLVTQSALASFIDEGLLSRHVRKATREYSARRDRILAFVRDELRDELEIV
                     PSSAGLHLCALLSPHATVTVDGVVAEAARAGVAVESLSTYGGTRGGLVLGYGLVGSDRI
                     DEGLSRLGECFPADGMS"
     aSDomain        8336..9130
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKN51_RS21565_Aminotran_1_2.1"
                     /evalue="9.00E-21"
                     /label="BKN51_RS21565_Aminotran_1_2.1"
                     /locus_tag="BKN51_RS21565"
                     /protein_end="414"
                     /protein_start="149"
                     /score="66.3"
                     /tool="antismash"
                     /translation="GYADPAGLEGLRVAIARHIGAARSVRASGEDVLVTQGAQQALDLI
                     GRVLIEPGTRVAVEDPGYPPAERLFAALGARVVKVPVDAEGLDVTALAPGIRLIYTTPS
                     HQFPLGTPMSLSRRTALLAWAERHDAVIVEDDYDSEYRFSDRPLEPLQSLDRDGRVLYV
                     GSFSKTLLPLLRLGFLVAPASLRPALRQAKQLMDWHGDLVTQSALASFIDEGLLSRHVR
                     KATREYSARRDRILAFVRDELRDELEIVPSSAGLHLCALLSPH"
     gene            9473..9916
                     /locus_tag="BKN51_RS21570"
                     /old_locus_tag="BKN51_21215"
     CDS             9473..9916
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155056.1"
                     /locus_tag="BKN51_RS21570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21215"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_101609343.1"
                     /transl_table=11
                     /translation="MAGETVLTVVGNLTTDPELRFTPSGAAVANFTVASTPRVLDRESG
                     EWRDGDPLFLRCSLWKQAAENLTESLTRGTRVIVQGRLKQRSFETKEGEKRTVVELDVD
                     EIGPSLRYATAKVNKAGRSSGGTPADGAWERTPVAAGSPEPPF"
     gene            10001..11029
                     /locus_tag="BKN51_RS21575"
                     /old_locus_tag="BKN51_21220"
     CDS             10001..11029
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335880.1"
                     /locus_tag="BKN51_RS21575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21220"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_233223657.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-47, bitscore:
                     161.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTTIITELGLDPADERHSAFSAELRSGLSLVEDRLQEVLRSPG
                     YPYLTEAATHLVRAGGKRLRPLMALAGASFGDGRDEAISAAVLVELVHVATLYHDDVMD
                     EAPMRHGVTSANSLWGNKKAVLIGDYVLACAARVGAGLGDYALRSQAKTFGRLVRGQFL
                     ETTGPFEDCGSHAPYEHHIQVMADKSASLIAMAGRLGGQVAGADERIIETLGQYGELIG
                     VAFQISDDVLDISASTTDLGKSAGTDLREGIVTLPMLHALDDEGPGAARLREIIGHGPV
                     PDPALRDEALGLLRGSAGVDRALAEAHGYAAKARDLALSLPDRPARALLIGLSAFVVDR
                     GE"
     misc_feature    complement(11121..11132)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.36"
                     /tool="antismash"
     gene            11198..11824
                     /locus_tag="BKN51_RS21580"
                     /old_locus_tag="BKN51_21225"
     CDS             11198..11824
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030030.1"
                     /locus_tag="BKN51_RS21580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21225"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_101609344.1"
                     /transl_table=11
                     /translation="MTDVADRSGDHTRQVDRFDQRRAQLAMSALVTLSELGYARTSLRE
                     IAQNSEFSHGVLHYYFRNKVELITYCVKQYKAECVTRYDRIVETAETAEELKQAFGAAS
                     ASTLREDARLHRLWYDLRNQSLFEKVFRADVLAIDETLELMIWRIVARYAELLDKPLDL
                     TPSTTYALFDGLFQQGLLKHLAGREDAARCLQDSVEQVLARLFTT"
     gene            complement(11814..12764)
                     /locus_tag="BKN51_RS21585"
                     /old_locus_tag="BKN51_21230"
     CDS             complement(11814..12764)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335883.1"
                     /locus_tag="BKN51_RS21585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21230"
                     /product="hypothetical protein"
                     /protein_id="WP_101609345.1"
                     /transl_table=11
                     /translation="MSITERVPVSPRSTFLGSGPYPEHRWRVVCWSVLAGFALTVIWSA
                     PFVDSVIGDSVANTLLGHNAKETPIGGVLAGTFFAFVSGLAGTFTACNIAAFGAVAPLV
                     GGETSGRPKFVDTLKPLAWIAAGMLTVSVVYGVIVALVGTRMPQFSTASSPGGLTPRNI
                     QSMIVYGVIGIVFIVLGLASVGIVRNPIAGLTRRFPPAPLVLMGVLIGGFLVGRPFPLF
                     RMMFRSAAESHNVFYGAAAFALQSVGNILVMALLFLLLTHGTGGRLQRWMLAKPARIAV
                     VTGAALLVAGTFTLLYWDLRVLGRTGVIWYPTITW"
     gene            13015..13884
                     /locus_tag="BKN51_RS21590"
                     /old_locus_tag="BKN51_21235"
     CDS             13015..13884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016335884.1"
                     /locus_tag="BKN51_RS21590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21235"
                     /product="hypothetical protein"
                     /protein_id="WP_101609346.1"
                     /transl_table=11
                     /translation="MEFDEVADELYAGDPAVFVSVRNQRAKEAKVAGDAALAERIRALR
                     KPTLAATILNRRAGSPELEELARLGEDLRRAHSALAGADLRKLTRQRQDLVNRILRGER
                     AMSEPVAREVEATLEAVVADPEVAALALAGRLSSGADSAGDQWLTSGFTPQPRREPAPE
                     REKPATVSHLDDRRKAKRKAAEKAEQEHTAKAREEAEREQKRVAEFNRLRREAADLAKA
                     CKQAEIDLARAERRAEKVTEKANDLRQRLADAELEEEATNGDTAAAQTTLDDLRGEAAR
                     IDEALEQF"
     gene            complement(13881..14444)
                     /locus_tag="BKN51_RS21595"
                     /old_locus_tag="BKN51_21240"
     CDS             complement(13881..14444)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030027.1"
                     /locus_tag="BKN51_RS21595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21240"
                     /product="hypothetical protein"
                     /protein_id="WP_233223665.1"
                     /transl_table=11
                     /translation="MSTSTVRRPPTTLTPRWRKLVLVVHVVSSLGWLGITMVNTVLTFT
                     SVFTDDPRRQHAAILMMDQVGGYLLLPVSLTALVSGIVLGVGTKWGLVRYKWVAIKLVL
                     TLIAVGLTVFSLLPGLRELAAAAESTMDGAFVDLGRRVDGFYPIIVSTTMYLTMTVLSV
                     YKPGGKTAYGRRVTATRVRERQPA"
     gene            complement(14441..14761)
                     /locus_tag="BKN51_RS21600"
     CDS             complement(14441..14761)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKN51_RS21600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_335645043.1"
                     /transl_table=11
                     /translation="MKPAEVVADGFGRVQEVVHEAVEGLDAGQLVASRSPASAKPTSTG
                     SSTTRGIRPSPSGFAWSACFPTTSSTPGRPRTSGGSYSAIRRRGAAPRRTTGAPRAETL
                     VA"
     gene            14861..15208
                     /locus_tag="BKN51_RS21605"
                     /old_locus_tag="BKN51_21250"
     CDS             14861..15208
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030025.1"
                     /locus_tag="BKN51_RS21605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21250"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_101609348.1"
                     /transl_table=11
                     /translation="MHAFDVLGDPVRRRILELLAGGELSSGDVTSVVRAEFGISQPAVS
                     QHLRVLRENGFTTVRAEGARRLYSVDPGPLKEIDGWLEQYRRFWTGPLDALATEIARGR
                     RERRKAAEETG"
     gene            15219..16055
                     /locus_tag="BKN51_RS21610"
                     /old_locus_tag="BKN51_21255"
     CDS             15219..16055
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630234.1"
                     /locus_tag="BKN51_RS21610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21255"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_101609349.1"
                     /transl_table=11
                     /translation="MRKGRGRAAVIAVASIVIVLSLVFAVTARSGHGKATTLWLSSEPP
                     PWITPTTPAMPSYSTAAPPPTTRPTLTVDSGCRPGRGPALEPVPEAVTRRVDAAWDRVE
                     RWLRAKAPTSAASLRPPATIERIAETQKRVGVTLPAELIASLLRHDGVTDIGESFSLPP
                     FNYPASTETVAGQAKVMCEVLQSTGDESVGHWWHGRFVPVAVSGGGDGLFLDQRAGTGR
                     LGEWDHEGSVNFDRWPATLTELLEQTATALETGGTVVGGYRPVVTENRALDWDFPR"
     gene            16104..17939
                     /gene="recQ"
                     /locus_tag="BKN51_RS21615"
                     /old_locus_tag="BKN51_21260"
     CDS             16104..17939
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155082.1"
                     /locus_tag="BKN51_RS21615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21260"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_101609350.1"
                     /transl_table=11
                     /translation="MAAPDIGTSEALETLNRVFGYDDFRGDQHAIVEHVIAGGDALVLM
                     PTGGGKSLCYQIPALVRPGVGVVISPLIALMQDQVDALRNLGVRAGFLNSTQDYAERNR
                     VEAAFLSGELDLLYLAPERLSVEATVRLLDRGKISLFAIDEAHCVSQWGHDFRPDYLML
                     SAVHERWPDVPRIALTATATATTHAEIASRLNLEDARHFVASFDRPNIQYRIIGKNSPQ
                     RQLLELLRTEHKGDAGIVYCLSRNSVEKTADFLVENGIPAVPYHAGLDARTRAKHQSRF
                     LREDGLTVVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPSTAWLAYG
                     LQDVVQQRKMIDMSEGSEAHKRSQSAHLNAMLALCETVECRRVQVLSYFGQKSEPCGNC
                     DTCLAPPETWDGTIPAQKLLSTIVRLQNERRQKFGAGQIIDILLGKSTPKVTQHRHDSL
                     KVFGIGTELKEPEWRAVVRQLLAQGLAAVEGDYGSLVLTEGSSEVLNGQRKVQLRREPE
                     RAAKAAARSSAKKAAAADMPAEAAPVFELLRSWRAAAAKEQGVPAYVIFHDATLRQIAT
                     KRPATLQELGTVSGVGENKLAKYGEQILETLSAES"
     gene            complement(17936..18154)
                     /locus_tag="BKN51_RS21620"
                     /old_locus_tag="BKN51_21265"
     CDS             complement(17936..18154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630236.1"
                     /locus_tag="BKN51_RS21620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21265"
                     /product="antitoxin"
                     /protein_id="WP_101609351.1"
                     /transl_table=11
                     /translation="MALLRKLTALAGTAGAVRAYVRKNPEKVSKVVNKAATFVDGKTKG
                     KYHNQIDGAVRKVDGMTGRPPRRPYDH"
     gene            18317..19291
                     /gene="add"
                     /locus_tag="BKN51_RS21625"
                     /old_locus_tag="BKN51_21270"
     CDS             18317..19291
                     /EC_number="3.5.4.4"
                     /GO_function="GO:0004000 - adenosine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /gene="add"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020660597.1"
                     /locus_tag="BKN51_RS21625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21270"
                     /product="adenosine deaminase"
                     /protein_id="WP_101613371.1"
                     /transl_table=11
                     /translation="MRDLSRLPKAHLHVHLESTIRPDTLRDLGEANGIAVPAEQPVFDG
                     FRAFGDYNGLLRSCLRRPEDFERVAREFCEDQVADGVRYAEVTFTAAAHGERLGEPDMP
                     LVSVLKGLSAGSAEHGLHWRVLLDHSRRRSVERARLTLDLARRYVQDGVFAIGLAGEEK
                     YPLAPFAGICDEAAEAGLRLIHHAGEDAGPASIREALELGHSERIGHGIRILEDVALVA
                     EVRERGIALEVCPSSNVTLGLVPSFEEHPLPRLVDAGLVVTLSTDVPSVTRTTLTDEFL
                     RTREAFAYDDLALAGLARASVDASFATAELKRAMHQEIDAWLR"
     gene            19368..20180
                     /locus_tag="BKN51_RS21630"
                     /old_locus_tag="BKN51_21275"
     CDS             19368..20180
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005155086.1"
                     /locus_tag="BKN51_RS21630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_21275"
                     /product="lytic murein transglycosylase"
                     /protein_id="WP_233223686.1"
                     /transl_table=11
                     /translation="MTASSPSTLDLMDQWQPPPKRRGPRGCVMLALLVVGALVAGAVWV
                     VVSLNDREPVPVKPEFVVPALKPAPRSAIPGDAGPLPAEPAKDAWIAKVSENTDIPRRP
                     LRAYVNAAEKAPARCDITWATIAGIGRTESQHARHDGSRAGEDGIVTPPIIGIPLDGSP
                     GVLAVVDTDKGALDGDAKWDRAVGPMQFLPATWKRYGVRASGDGAAPDPQNIDDAAMTT
                     ARYMCARGGDLGKPAGWWSAVLTYNNSAQYGQEVFSNADAYGKAALKP"
     misc_feature    19941..19943
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ccttccgaat ctgatcagaa ttcttccccg gcagccgatc ctccaacaac gcatcagcag
       61 ccaacgcatc ctcatccgac aaccacgccg tcgccgccgc gaccttcatc gccccggacc
      121 cactcagctt cccctgatcc atcagcccca aggtccgggg cagacgggtc gtcaaggctt
      181 tggcggcggc gaccatcgca cccgcatgac cgtccacaac agacaacgcg aaagcgacct
      241 cctgcaccac actccgcgca ccatcccgat gccgagacaa ctgcgcgatc gcccgaaacc
      301 gcaccgcctc caaccgcgcg atatcagccg acacagcctg cgccagagcg acacactcct
      361 cgtcacccaa cgtgcgagga tcaggaaatt ccttcaaggg agccataaag gcttcagtag
      421 tagccacccg acgaacctac aaccagccac cgacagtttc cggaaaccgg aagcaccaag
      481 caacaaatcc tcgaaccacc ccaagacaag aactgcgtca ccgcaacaga agcctcaccc
      541 gaaaactgct ccctccaacc aatatgcctc cctgtcaagg aatccgacga ccccttccac
      601 cgaaacctcg cgaaccccgc tccctgcgag caacctccga aacccgcgcg ccgcccgggg
      661 cgcggtgatc gccgaagcgc gggcacgcac gatctcccgt gtcagtgccg gatgcacaga
      721 atcgatcacc agcgcctccc attcgtgccc ggacagcacg atccggccac ccggaaccag
      781 aacccgccgc gcctccgcga gagcgagctc cggctccgcc agttcgtgga aaccttgtcc
      841 gcccggtacc ccgcgaaccc cgccgtccac gggcagcgcg taagcgtctc cgacccgaaa
      901 gtccgcctca ggagaccgcc gtcgggcctc gtcggccatc tcgggagaaa ggtcgacacc
      961 gacgacggaa tccgtcggcc tccgcaagcc cgcgcggaac aaggatttca cccggtgcgc
     1021 gcacttccgg gcggcggtgg cgcgggccgg ctgacccgcg ccaccgtctt actcagccga
     1081 gcagtgcccg catctcggtg atctcggcct gctgaccgtc gatcaccttc tgcgccaagg
     1141 ctttgacctc ggcgtcgccg ccctgccgca gcgcggtctt cgccatcgcg agcgcaccct
     1201 cgtgatgctt gaccatcatc tccagccatt gcttgtcgaa ggcggcatct ttggctttgc
     1261 cgagttccgc cagatcgtcg tcggccatca tgccgtgccc ggagtgcccg cccgacggcg
     1321 tcactcccca gcctttcagc aatccggtca actgctggat ctccgggtcc tgcgcctttt
     1381 ggatcctcgc ggcgagatcg acgatcttcg cgttgcgagt acgtccgtcg acgagtttcg
     1441 ccatcgagag cgcctgttcg tggtgcggga tcatcccttg cgcgaaggtg acgtcggcct
     1501 cgttgtgccc cgcttgctgc gggttcggca cattcatcgt ggacatggcg tgcccgctgg
     1561 aggcggtgtc ggaactggcg catccggtga gcacgacaaa ggaggccagg gcggcgagcg
     1621 ccgccccgac cagtttcctg ctggtcatgg tttcttcctc gagtaagtgt cgggcagggc
     1681 gagacgtgcc cgcctgtcac acccgcagca cgcagaggaa ggacaatcgc tgaggaaccg
     1741 gtctccagcg cggaggatca cgccccggcg ccgcaccgcc acccggccgc gaactccacg
     1801 tcgccatggt ccgtccactt cggacgagca gccaggtgac gatcagcagc gcggccgcgg
     1861 cgagcaccgc gagacacagg tgcagtccac tgtgtccacc gtcgtcgtgc gaaggcgtgt
     1921 cctcgcaaca gggatccgcc atcgcgacgg cggagtgccc cgcgccgtga ccggtctcgg
     1981 cgatgacgtg atgcatgccg accagtccca gcgccaccac gcacaacaac agccaccgca
     2041 gggcggccgg gtacgaggac tgggtcacga ccccaccgta gccggattca gcgcgccgcc
     2101 ggccggtggg gtttccccgc cgaatgcagc gcggggatgt cgcggtcgat gtggtcggcg
     2161 tggaacaacg cctgcgcgag caggccgcgg acgtggtcgt tggccgccga gtagtagacg
     2221 aacgtcccct cgcgacgccc cttgaccagc ccggcgagcc gcagtttcgc gagatgctgg
     2281 ctgaccgccg tcggcgccgc gcccgccagt tccgcgaggc aggcgaccga ggactcacct
     2341 tgcagaagcg cccagaggac cttgatccga gtcggatcgg cgagcagccg gaacgtctcc
     2401 gcggccaggt ggacctgttc ctcggtgggc atctcgaaat ccggaaccga ctcgtgcatc
     2461 cccggaggat acccgttacc cttctacctg cgtatctgca tgactgcgca gatagcatga
     2521 cagtgaggcg ggaaatgacc gggcacggac acagtcatgg ccacaagccg gggaagagcc
     2581 gtctccgcca tctgctgacc ccgcacagcc acgacagcgc cgaccgcgtc gacaccgcgc
     2641 tggagaccag caaacgtggt gtccggacgc tgatctggtc gttcgccgcc ctgttcgtca
     2701 ccgccgtcgc ccagctcgcg ctcgtgctgg tcaccggttc ggtggcgtta ctcggcgaca
     2761 cgatccacaa cttcgccgac gcgctgaccg cggtcccgct cggcatcgcc ttcctgctcg
     2821 gccgccgcgc ggccacccgc cgctacacct acgggctcgg gcgggccgaa gacctcgccg
     2881 gagtgctcgt cgtcctgctc atcgccgcct cggccgtcct cgccgggtac gagtcgatcg
     2941 agcggctgct cgatcctcgc ccggtccggc atctgtgggt ggtcgccgcg gcgggggtaa
     3001 tcggcttcgc gggcaacgaa ctggtggcca ggtaccggat caccgtcggc cgagagatcg
     3061 ggtccgccgc gctggtcgcc gacgggctgc acgcgcggac ggacggcttc acctcgctcg
     3121 cggtcgtgct cggcgccgtc ggggtcggct tcgggttccc gctggccgac ccgatcatcg
     3181 gcctcgccat cacggtcgcg atcctgttcg tcctgcgtga cgccgccaag gaggtcttcc
     3241 gccgcctgat ggacgccgtc gaccccgccg acgtcgatcg cgccgaacgc gcggccgccg
     3301 aggtacccgg cgtactcggc acgcgcgacc tgcggatgcg ctggatcggc cacagcctgc
     3361 gcgcggagct ggcgatttcg gtcggggcgg aactgaccgt caccgaggcg catcacctcg
     3421 cccatctcgt cgagcgacga ctgcgccagg tgctgccgcg gctcgcggaa gcggtcgtgc
     3481 acacggaacc ggcgcacgct catgagatcg tcagcgggtg acgctgtccg acaacgacat
     3541 ccgcgccgtc cgcgcccgcg cgcaacggct cgattccccc gccggcgacc tgctcgccgt
     3601 ggccaggtcc ctcgccgcga tccaggcgca gtcgagtccc gccgccaggc tcgcggtccg
     3661 ggtccgcagc cggggcctga tcgcgccgga cgtcgacgcg tcccgcgaag tggcgcgcac
     3721 ctggctgatg cgcaagacgc tccacctggt cccggcggcg gatctccgct ggctgaaccg
     3781 gctgttcggc ccgcgcaacg cccagtccgg ccagggacgc cgaacgcaac tgggcctcac
     3841 cggagaactc tgcgaacgcg cgctgaaaca cctccaggat ctcttgcgag gcaaggcact
     3901 cacccgccgg gagatcctgg acggcctggc gtccgacggc atcacgctcg acgcgaaatc
     3961 ccaggcgccc gcccacctcc tggcgtacgc ggccaaccgc gggttgctct gccggggcca
     4021 ggacgtcgga tcggaaccga cgtacgtgct cctcgacgag tggatcaccg aggacgacac
     4081 cccggacgac ccgcgggcgg aactcgcccg ccggtacctg accgcgtacg gcatcgcgac
     4141 ggccgaggac ttcggcgcct ggtccgggtt cccgctcggg ctctgccgcg aggctttcga
     4201 cgcgctggat ctcgtgcccg ccggcagtgg cttcgccctc gcggagaccg agctgaccgc
     4261 tcccccgtgt cccccgcgcc tgctcggcgc cttcgacacg tatctgctgg gctaccgcga
     4321 ccgcgatctg cttctcgacc cggccgaagc gaagcgcgtc aactccggtg gcgggatgat
     4381 cgcgcccacc gtgctcgtcg acggccggat cgccggaacc tggcacgccg aacggaccgc
     4441 gaagcagacg aaggtcgtca tcgaaccctt cgccgcgctt tcgcggtccg ccgtcaccgg
     4501 acttgagtcc gaagtggacg attacggccg cttcctcggg gaagcggccg tcctcgtcat
     4561 ttgagcgacc ggaagaactc ccgcacgtcc gcgaccagga tctcgggctc ctccagcgcc
     4621 gcgaaatgcc cgccgcgatc gacgtcggtc caccgcacga tcgtgtgcgc gtcctccgag
     4681 taccgccgga tcccgacgtc gtgcgcgaag atcagcaccg ccgtcggcac cccggagttc
     4741 ttctcgacgg ctccccaggt ttccgcctgc gcgtacccga cgtacgcgga cgacgcggcc
     4801 gtgccggtga gccaggtgaa catgacgttg gtcagcaacc ggtccctgcc gatgatctcc
     4861 tccggcagcg tcgggcgcgg atgcgtccac tcgcggaact tgtccatgat ccaggccagc
     4921 tgcgcgaccg gggagtcgat cagcccgtaa cccagggtct gcggccgcgt cgactggatc
     4981 gagatgtacc cgaactcctc ctgcatgaag gcctcgatcc gcgtgatccg atcgcgttcg
     5041 atgtcggtga gcgaggcgag ttcctcctcc ggcaacgaca tcgggggcat cgggctgagt
     5101 ccgccgttga cgtgcactcc gatcaccttg tccggcgcca cccggcccac ctccggcgag
     5161 acggaagcgc cgaggtcgcc accctggacg ccgtagcgtt cgtagccgag cctgcgcatc
     5221 agctcggccc aggcccggcc gatccgcggc atggtccagc cggaatccga gacggggccc
     5281 gagaaaccga agccgggcag cgacgggatc acgaggtgga acgcgtcccc gctctcgcca
     5341 ccgtgcgcct tcgggtcggt gagcgggccg atgacgtcga ggaattccac caccgaaccc
     5401 ggccagccgt gcgtgaggat cagcggtgtc gcgccggctt cgggcgagcg gacgtgcagg
     5461 aagtggatgt tctgcccgtc gatctccgtc gtgaactgcg ggaaccggtt gatctcgcgt
     5521 tcggcggcgc gccagtcgta gccgtcgcgc cagtactcgg cgagtccgcg caaccaggac
     5581 accggcaccc ctgtgtccca gccgtcgccg gggagcggag ccggccagcg cgcgctgtcg
     5641 agcttcgcgc gcagttcgtc cagctgctcc tgggggacgt cgaggaggaa ggggcggatc
     5701 tcggtgtttt ccatgactcc tacgctaaag agcattgcgg acagtttctg tcctcgatcg
     5761 aaaagggttc acggatacgg gaagatgcgc gggtgaagga caagtacttg gcctacggca
     5821 ggctcatccg cgacgggaag atcctgttca tccggcgacg gcccggctct ttcctcggcg
     5881 gtcattggga actgccgggc ggcaccgtcg agccgggcga gcggcaggcg gagaccgtgg
     5941 tccgggagtt cgccgaggag accgggctga ccgtgcgggt caccggcgag aacggtgctc
     6001 acagctggga cgacgtcgag ggcaggccga tgcggatcca cgccacggtg ttctcgctcg
     6061 ccgaagagga accgcgcgaa gtcgtgctcg atcccgagga acacgacgcc ttcacttggt
     6121 acaccaggga agaagccgcc gggctcgacc tcgccgagca cttccgccgg gcgatcgagg
     6181 actgaggccg ggacccgtcc cgggtgggcc tccctaccct gcccggcatg cttcgacgcc
     6241 ttgtagtgcc cctcgccgcc ctccttctcg tggcgggctg cggtccggac tcacccgagc
     6301 cgccgaaacc cgccgacggc ggtgatctcg ccgcctgctc cgacgggatg tgcgaggtca
     6361 gcgcgccggt gggcggcaag atgacgcttc ccgagcggac gagggtcgaa tcggtgaccg
     6421 ttcaatcagt cgaaggcgac accgtcgtgc tggtcgcccg cggtatcggg ccaaggcaag
     6481 gcggaagctg caccggcaag aagtgtgaag cctcagccaa gggccccgac ttcaaggccg
     6541 cgctcgggcc gggcagcggc gtcacctaca acgacctcgc gatcgacctg ctgggcatcg
     6601 gtgacggcgc cgccgttctc cggatcaaac cgctgtgagc tccgctccgc ccagcggacc
     6661 gctggcgcgg tgagcgcgcc caccagcagg aacaggccgc ccagcaccac ccagcccgcc
     6721 tcgccgccca ccaggatcag gctggtgagc agcaccgggc cgagcatgcg ggcgatggcc
     6781 gtcccggcac cgaagagccc ttggtactgg ccctgtctgc cctcgggcgc caggccgaag
     6841 ccgatctccc acgagcccgc cgcctgagcc atttccccca ccacctgcaa cgcggcaccc
     6901 gcgagcagga ccagcgccgc cgtccaggcg gaggcgctca tcgcggagaa cgagaagacc
     6961 agacaggaga cgaacagcag cgaacccgcg taccgggcgt accgggaggc actgcgcagg
     7021 ccggtcacgc cccgcgccac ccgcacctgg aagaccacga cgctcgccgt gttgagcacc
     7081 agcatcgccg acaccagcca gccgggggcc gcggtcctcg tcgagatcca cagcggcagg
     7141 accaggctga acagcggcat gtagagcaac atgatcatgt tgagcagcgc cagcagcgcg
     7201 tacgggcggt cgcggagaac ggccacggac ggctcgccgg tccgcaccgg cgccggggcc
     7261 accgatggca gcttgcggag cacgagagcc gcggtgacga aactcagcgc gtcgatgacg
     7321 aagacggtca ggaaggcctc tcgcgtcccg agcgccagcg cgattccgcc gagtgccgcg
     7381 ccgagcgcga tccccgcgtt ggacatcgcc tgcagccggg cgcggaacgt cgtgcgcccg
     7441 gccgggtcga tcaggccggc gagcagcgcc tgcctcgccg cgccgagacc gcattggaag
     7501 caggcgtaga cgcaggccgc gatcacgaac gcgaccaccg agttgacgaa aaggaaggcc
     7561 gtgaccgacg cggccgtgcc gagtcccagc acgacggccg ttcccttcgg gccgcgacgg
     7621 tcggccagct gccccagcgc gaccccggcc accgagccga ccgcccagcc gacggtgagg
     7681 ccgaggccca cgtgcgcggg cgaaagcccg acgatcaggg tgaagtacag ggccgagctg
     7741 acgtagtagg cgccgtcgcc gacggagctg atcagctggg ccagcgccag tctcttcgtg
     7801 gactccatgg agccaagcta agcgccggat tggccacatc ccagttccaa taaccggcat
     7861 tctgattggg ccaatatagg ctcggagcgt gccgttccac atcagtctcg acggtcatac
     7921 cgacctggcc gcgcggatct accgccagct ccgcgacggc atcctcgacg ggcgcctgcg
     7981 ctctggagaa cgcctgccgc cgaccaggga gctggcccgc gaactcgacg tctcgcgcaa
     8041 caccgtcgcg gtcgcctacg aacgcctcac cgcggagggc ttcctgagca gccatgtcgg
     8101 acgcgggacg ttcgtcagcg ccgatcccgt gggccgggcg gatcgcgccg cgccgtcggg
     8161 cgccggagtg ctgccgtccg cgcactggcg ttcgcttccg gccccgctcg gcgccgaccg
     8221 ctccacgccc gccttcgact tccgcgtcgg cgtccccgac ccggccctgt tcccgctgag
     8281 cacctggcgg cggctggtca gccaggcgct tcggccctcg ttgctgccgc cgtcgggcta
     8341 cgccgacccg gccgggctcg aaggcctgcg ggtggcgatc gcccggcaca tcggcgccgc
     8401 ccggtcggtg cgggcgagcg gggaggacgt cctcgtcacc caaggggcgc aacaggccct
     8461 cgacctgatc ggccgggtcc tgatcgaacc cggcacgcgg gtcgccgtcg aagaccccgg
     8521 ctatccgcct gcggaacggc ttttcgccgc cctcggcgcc cgggtcgtga aggtgccggt
     8581 ggacgccgaa ggcctcgacg tcaccgccct cgcgccgggc atccggctga tctacacgac
     8641 gccctcgcac cagttcccgc tcggcacgcc gatgtcactc tccaggagga cggcgttgct
     8701 ggcgtgggcg gagcgccacg acgcggtgat cgtcgaggac gactacgaca gcgagtaccg
     8761 gttctcggac cggccgctcg agccgctcca aagcctggac cgcgacggca gggtgctcta
     8821 cgtcgggtcg ttctcgaaga ccttgcttcc cttgctgcgt ctaggtttcc tcgtcgctcc
     8881 cgcttcgctg cggccggcgt tgcggcaggc gaagcagctg atggactggc acggtgacct
     8941 cgtcacccag tcggcgttgg cgagtttcat cgacgagggc ctgctctccc gtcacgtacg
     9001 caaggccacc cgggagtact cggcgcggcg ggaccggatc ctggccttcg tccgcgacga
     9061 actgcgggac gagctggaga tcgttccttc gagcgccggg cttcacctgt gcgctctcct
     9121 ctctccacat gcgacggtca ctgtggacgg tgtcgtcgcg gaagcggcgc gagccggggt
     9181 ggccgtcgaa agcctttcca cgtacggggg aacgcgcggc gggttggtcc tcggctacgg
     9241 actggtcggc tccgatcgga tcgacgaagg gctttcccgg ctcggggagt gctttccggc
     9301 cgacgggatg tcatgaaagg ggctttcaag acagctttcg tcttgaaagc ccctttcatg
     9361 acatccgatc gccacgggac gcccgaaact gtcgtacccc ggtggtctcc tcttcccagg
     9421 cgacagcggg ccccggccgg ggcccgcgcg cggaagcgag gaggcaagtc ccatggccgg
     9481 agagacggtg ctcacggtgg tcggaaacct gacgaccgac ccggaactga ggttcacccc
     9541 gtcgggagcg gcggtcgcga acttcacggt cgcgtcgacg ccgcgcgtgc tggaccgcga
     9601 gagcggggaa tggcgcgacg gcgacccgct gttcctgcgc tgctcactct ggaaacaagc
     9661 cgcggagaac ctgaccgagt cactcacccg cggcaccagg gtgatcgtgc agggccggtt
     9721 gaaacagcga tccttcgaaa cgaaggaagg cgagaaacgg acggtggtgg aactcgacgt
     9781 cgacgagatc ggcccgtcgc tgcgctatgc cacggcgaag gtgaacaagg cgggccgcag
     9841 ttcgggcggc accccggcgg acggcgcgtg ggagcggacg ccggtggccg ccgggagtcc
     9901 ggaaccgccc ttctgaaccg gcgatttccc tctcgggagg gaccggtctc ccccgcccgc
     9961 gccatgcggt cccgtgccct cggctcggat gctggaggtc gtgaacacga ccacgatcat
    10021 cacggaactc gggctggatc cggccgacga gcggcactcg gccttctccg ccgagctccg
    10081 ctccggcctg tccctggtcg aagacagact tcaggaggtg ttgcgcagcc ccggttatcc
    10141 gtatctcacc gaagcggcca cccatctcgt ccgcgcgggc gggaagcggc tccggccgtt
    10201 gatggcgctg gccggagcgt cgttcggcga cgggcgggac gaggcgatct cggcggcggt
    10261 gctcgtcgag ctcgtccacg tcgcgacgct ctaccacgac gacgtcatgg acgaggcgcc
    10321 gatgcggcat ggggtgacga gtgcgaattc cttgtggggc aacaagaagg ccgtcttgat
    10381 cggagactac gtgctcgctt gcgcggcgcg ggtcggtgcc gggctcggcg attacgcgtt
    10441 gcggtcgcag gcgaagacgt tcggcaggct cgtccggggc cagttcctcg aaacgaccgg
    10501 gccgttcgag gactgcggca gtcacgcgcc ctacgaacac cacatccagg tgatggccga
    10561 caagtccgcg tcgctgatcg cgatggcggg acggctcggc ggccaggtgg cgggcgccga
    10621 cgagcggatc atcgaaacgt tgggccagta cggcgaactg atcggcgtcg cgttccagat
    10681 ctccgacgac gtcctcgaca tctccgcgtc caccaccgac ctcggcaagt cggcgggcac
    10741 cgacctccgc gagggcatcg tcaccctgcc gatgctccac gcgctcgacg acgagggtcc
    10801 cggcgccgcg cgtttgcggg agatcatcgg gcacgggccg gttcccgacc ccgcgctccg
    10861 ggacgaggcg ctcgggctcc tgcgcggctc cgccggtgtc gatcgcgccc tggcggaagc
    10921 tcacggttac gccgccaaag cacgggacct cgcgctcagc ctccccgacc gcccggcccg
    10981 agcgctgctg atcggtcttt cggcgttcgt ggtcgaccgc ggcgaatagg cccacggcgg
    11041 ccgtgaccgg ggtcaaggtg gcgggatgac cagcgaccat ttcatcaccg agtggctcga
    11101 ataaattctg tcggacgcaa gaaaaccctt tccggggcta gaatccgacg atgtgctcgt
    11161 ggccggcggg cacccgagac gacgggaacc gggaactgtg accgacgtgg cggaccgcag
    11221 cggtgaccac acccgccagg tggacagatt cgatcaacgg cgcgcgcagc tggcgatgtc
    11281 ggcgctggtc acgctgtccg aactgggcta cgcgcgcacg agcctccggg agatcgcgca
    11341 gaactccgag ttctcccacg gggtcctgca ctactacttc cggaacaagg tcgagctgat
    11401 cacctactgc gtcaaacagt acaaggccga atgcgtcacc cggtacgacc ggatagtcga
    11461 gaccgcggaa acggccgaag aactgaaaca ggccttcggc gccgcgtcgg cgtccaccct
    11521 gcgcgaagac gccaggctgc atcggctctg gtacgacctg cgcaaccaaa gcctgttcga
    11581 gaaggtgttc cgggccgacg tgctcgccat cgacgagaca ctcgaactga tgatctggcg
    11641 gatcgtcgcc cggtacgcgg agctactgga caagccgctg gatctcacac cgtcgacgac
    11701 gtacgcgctc ttcgacggcc tgttccagca aggcctgctg aaacacctcg ccggccggga
    11761 ggacgcggcg aggtgccttc aggattcggt ggagcaggta ctggcgcgcc ttttcaccac
    11821 gtgatcgtcg ggtaccagat gacgccggtc cggcccagta cccgcaggtc ccagtacagc
    11881 agcgtgaacg tgcccgcgac cagcagcgcg gcgccggtca ccacggcgat cctggcgggc
    11941 ttggcgagca tccaccgctg cagccgcccg cccgtgccgt gcgtgagcag caggaacaac
    12001 agcgccatca ccaggatgtt gccgaccgac tggagggcga acgcggcagc gccgtagaag
    12061 acgttgtggc tttcggcggc gctgcggaac atcatccgga acagcgggaa cggcctgccg
    12121 acgaggaatc cgccgatgag cacgcccatc aggacgagcg gcgccggcgg gaaccggcgg
    12181 gtgaggccgg cgatcgggtt gcggacgatg ccgacggaag cgaggcccag cacgatgaac
    12241 acgatcccga tcacgccgta gacgatcatc gactggatgt tccgcggtgt gagcccgccc
    12301 ggcgacgaag cggtggagaa ctgcggcatc cgggttccga cgagggcgac gatgacgccg
    12361 tacaccacgg aaacggtcag catgcccgcc gcgatccagg ccagcggctt caaggtgtcg
    12421 acgaacttcg gccgcccgga ggtctctccg ccgacaagcg gggcgaccgc accgaacgcg
    12481 gcgatgttgc acgcggtgaa cgtaccggcg agccccgaaa cgaacgcgaa gaacgtcccg
    12541 gcgagcacac cgccgatcgg ggtctccttg gcgttgtgcc ccaggagggt gttggccacg
    12601 ctgtcaccga tcacactgtc cacaaagggt gccgaccaga tcaccgtcag cgcgaaaccg
    12661 gcgaggacgg accagcagac cacacgccac cggtgttccg gatacggtcc ggagccgaga
    12721 aaggtcgatc gcggggaaac ggggacgcgt tcggtgatcg acattcgtac ctccagcgaa
    12781 ggactccccc aggactcgta ctcatcgttg ttccgcggaa gggggtgcgc cacctccaaa
    12841 gtgccgatcc acccttggtc cgatcggctc cgggtaatcc ggagtgcggg cggctccgct
    12901 cgtgaagcgt cgatccatcg gatcctgaca aacaacctcg aaaagatgag agcgccgaag
    12961 tttcgtggga tcctcgtcgg acgaggtttt cggctacgga cccagcggag gacgatggag
    13021 ttcgacgagg tcgcggacga gctctacgcg ggcgatccgg ccgttttcgt gtcggtgcgc
    13081 aatcagcggg cgaaggaggc caaggtcgcg ggcgacgccg ccttggccga acgtatccgt
    13141 gcgctccgga agcccacgct cgcggccacc atcctcaacc gccgggccgg ttcccccgaa
    13201 ctggaggagc tggcccgact cggcgaggat ctgcggcgcg cgcattcggc gctggcgggc
    13261 gcggacctgc gcaagctcac ccggcagcgt caggacctgg tgaaccggat cctgcggggc
    13321 gaacgcgcga tgagcgagcc cgtcgcccgt gaagtcgaag cgaccctcga agccgtcgtc
    13381 gcggatcccg aggtggccgc gctcgcgctg gccgggcggt tgagcagcgg cgcggacagt
    13441 gccggcgacc aatggctgac cagtgggttc accccgcaac cgaggcgaga acccgcgccg
    13501 gagcgggaaa agcccgccac cgtgtcgcat ttggacgatc ggcggaaggc aaaacggaag
    13561 gccgccgaaa aggccgagca agagcacacc gccaaggctc gcgaggaggc cgaacgcgag
    13621 cagaagcggg tggcggagtt caaccggctc cggcgcgagg cggccgatct cgcgaaggcc
    13681 tgcaagcagg ccgaaatcga cctcgcccgc gcagaacgcc gggccgagaa ggtcacggag
    13741 aaggcgaacg atctccggca gcggctcgcc gacgccgagc tcgaggaaga ggcgacgaac
    13801 ggtgacaccg ccgccgccca gaccaccctg gacgatctgc gcggcgaagc ggcgcggatc
    13861 gacgaggccc tcgaacagtt ctaagcaggc tggcgttcgc ggacccgcgt ggcggtcacc
    13921 cggcggccgt aagccgtctt cccgcctggc ttgtacaccg acaggacggt catggtcagg
    13981 tacatcgtcg tggacacgat gatcggatag aacccgtcca cgcgacggcc caggtcgacg
    14041 aacgcaccgt ccatagtgga ctcggcggcc gccgccagtt cccggagtcc cggcagcagg
    14101 gagaacaccg tcagcccgac cgcgatcagg gtcagcacca gtttgatcgc gacccacttg
    14161 taccggacca gcccccattt cgtgccgacg ccgagcacga tcccgctgac cagggcggtc
    14221 aggctgaccg gcagcaggag atagccgccg acctggtcca tcatcaggat ggccgcgtgc
    14281 tggcgccggg gatcgtcggt gaacacggag gtgaaggtca gcaccgtgtt caccatggtg
    14341 atcccgagcc agccgaggga cgagacgaca tggacgacga ggacgagttt ccgccaccgc
    14401 ggggtgagcg tcgtcggcgg tcgccgcact gtggaagtac tcatgcgacc agtgtttccg
    14461 cgcgcggcgc tcccgtcgtc cgtcgaggag cggcacctcg cctacgtatc gcggagtacg
    14521 agcccccgga cgtacgcggc ctgcccggcg tgctggaggt cgtcggaaag cacgctgacc
    14581 aggcgaaccc cgagggtgac gggcggatcc cacgcgtcgt cgacgatccg gtcgaggtcg
    14641 gcttcgccga ggcaggcgac cggctcgcga ccagttgccc ggcgtccagg ccctcgaccg
    14701 cctcgtgcac gacctcctgg acacggccga atccgtcggc caccacttcg gccggtttca
    14761 tcgattcccc ttccgacgtc tggggcccgc gatgccaccg cgaggtgacc tcagccttgc
    14821 aaccttgact tatataagcc caggccgtga tagttgccgg atgcacgcgt tcgacgtcct
    14881 gggggatccg gtgcgccgcc ggatcctgga actgctggcg ggcggggaac tgagttccgg
    14941 cgacgtgacc tcggtggtcc gcgccgaatt cgggatctcg caacccgcgg tctcccagca
    15001 tctgcgcgtc ctgcgcgaga acggcttcac caccgtccgc gccgagggcg cgcgacggct
    15061 gtactcggtg gatcccggcc cgctcaagga gatcgacggc tggctggagc agtaccggcg
    15121 attctggacc ggtccgctcg acgcgctcgc caccgagatc gcgcgcggtc gccgcgaacg
    15181 acgcaaggcc gccgaagaga ccggatagtc tgccgcccat gcgcaagggc cgggggcgcg
    15241 cggcggtgat cgccgtcgcg agcatcgtca tcgtgctgag tctcgttttc gcggtcacgg
    15301 cgcggagcgg gcatggcaag gcgacgacgc tgtggctctc ctcggagccg cccccgtgga
    15361 tcacaccgac gacaccggcg atgccgtcct attcgaccgc cgcgcccccg cccacgacgc
    15421 ggccgacgtt gaccgtcgac agcggttgcc gtcccggtcg gggcccggcc ctcgaaccgg
    15481 tccccgaagc cgtcacccgc cgggtggatg ccgcctggga ccgtgtcgaa cggtggctca
    15541 gggccaaggc gccgacgtcg gcggcgagcc tccgcccgcc cgcgacgatc gagcggatcg
    15601 cggagacgca gaagcgggtc ggcgtcaccc tccccgccga gctcatcgcc tcgcttctgc
    15661 ggcacgacgg cgtcacggac atcggcgaaa gcttcagtct tccgccgttc aactaccccg
    15721 cttccacgga aaccgtcgcg ggccaggcga aggtcatgtg cgaggtgctg cagtcgaccg
    15781 gggacgagag cgtcggacac tggtggcacg ggcgattcgt gcccgtcgcc gtcagcggcg
    15841 gcggcgacgg gctgttcctc gaccagcgcg ccggcaccgg ccggctcggc gaatgggacc
    15901 acgagggatc ggtgaacttc gaccggtggc ccgccaccct gaccgaactg ctggagcaga
    15961 ccgcgacagc actcgaaacc ggcgggacgg tcgtgggcgg ctaccggccg gtcgtcaccg
    16021 aaaaccgggc gctggactgg gacttccccc gctgaggtgc gcggccgcgt cgactgtcgg
    16081 accccgcccc tagaatcgtc cgggtggcag cccccgacat cggtacctcg gaagccctcg
    16141 aaacgctgaa ccgcgtcttc ggctacgacg acttccgcgg tgaccagcac gccatcgtcg
    16201 aacacgtcat cgcaggcggt gacgcgctcg ttctcatgcc caccggcggc gggaagtcac
    16261 tctgctacca gatccccgcc ctggtacggc cgggtgtcgg cgtggtgatc tcacccctga
    16321 tcgcgctgat gcaggaccag gtcgacgcgc tgcggaacct cggcgtgcgc gcgggattcc
    16381 tcaactcgac gcaggactac gccgagcgca accgggtcga ggccgcgttc ctctccggtg
    16441 agctggacct gctgtatctg gcgccggaac ggctttcggt cgaagcgacc gtgcggctgc
    16501 tcgaccgcgg caagatctcg ctgttcgcga tcgacgaggc gcactgcgtc tcccagtggg
    16561 gccacgactt ccggcccgac tacctgatgc tgtccgcggt gcacgagcgc tggccggacg
    16621 tgccgaggat cgcgctcacc gccaccgcca ccgccacgac gcacgccgag atcgcgtccc
    16681 ggctcaacct cgaggacgcg cggcacttcg tcgcgagctt cgaccggccg aacatccagt
    16741 accggatcat cggcaagaac tcaccgcaac gccagttgct cgaactgctg cgcaccgagc
    16801 acaagggcga cgcgggaatc gtctactgcc tgtcgaggaa ctcggtcgag aagaccgcgg
    16861 atttcctggt ggagaacggg atcccggcgg tgccctatca cgccgggctg gacgcgcgga
    16921 cacgcgcgaa acatcagtcg cgcttcctgc gcgaggacgg gctgaccgtc gtcgcgacga
    16981 tcgcgttcgg catgggcatc gacaagccgg acgtgcggtt cgtcgcgcat ctggacctgc
    17041 cgaagtccgt cgagggctac taccaggaga caggccgcgc gggccgtgac gggctgccgt
    17101 cgacggcgtg gctggcgtac gggctccagg acgtcgtcca gcaacgcaag atgatcgaca
    17161 tgtcggaggg atccgaggcg cacaaacggt cgcagagcgc ccatctcaac gcgatgctgg
    17221 cgctgtgcga gacggtcgaa tgccgtcgtg tgcaggtctt gagctacttc gggcagaaga
    17281 gtgagccgtg cggcaactgt gacacctgcc tggcaccgcc ggagacctgg gacggcacga
    17341 tcccggcgca gaagctcctc tccaccatcg tccggctgca gaacgaacgg cggcagaagt
    17401 tcggcgcggg gcagatcatc gacatcctgc tcggcaagtc gacgccgaag gtgacccagc
    17461 accggcatga ttccctgaag gtcttcggga tcggcacgga attgaaggag cccgagtggc
    17521 gggccgtggt ccggcagctg ctggcgcagg ggctcgcggc ggtcgagggc gactacggct
    17581 cgctcgtgct gaccgagggc agctccgagg tgctgaacgg gcagcggaag gtccagctgc
    17641 ggcgggagcc cgagcgcgcg gcgaaggcgg cggcccggtc cagtgcgaag aaggcggcgg
    17701 ccgccgacat gcccgccgag gcggcgccgg tgttcgagct gctgcgctcg tggcgagccg
    17761 cggcggcgaa ggagcagggg gttcccgcgt acgtgatctt ccacgacgcg accttgcgcc
    17821 agatcgccac caaacggccc gccacgctgc aagaactcgg gacggtcagc ggcgtcggcg
    17881 agaacaagct cgcgaagtac ggcgagcaga tcctcgagac gctgtcagcg gagagctagt
    17941 ggtcgtaggg ccggcggggc ggccgtccgg tcatcccgtc gaccttgcgc accgcaccgt
    18001 cgatctggtt gtggtacttg cccttggtct tgccgtcgac gaaggtcgcc gccttgttca
    18061 cgaccttgga gaccttctcg ggatttttcc gcacgtaggc gcgcacggcc ccggcggtgc
    18121 cggccagggc ggtcaacttc cgcagtagag ccacgatggg tccctttcct cggggtcgtc
    18181 tgtgtcctgc tcaacgaccg gtggtggtca cggggttccc cgtagcgcgc caaatcactc
    18241 atttcggata cccgcgctgc tcagcgtggt ggaaaaccgc gagcgcggcc cggcggcgcc
    18301 cgctaagttc gggctcatgc gggatctttc gcggctgccc aaggcgcatc tgcacgttca
    18361 cctcgaaagc accatccgac cggacacgct ccgtgacctc ggcgaggcga acggcatcgc
    18421 cgtacccgcc gaacaacccg ttttcgatgg gttccgcgcg ttcggcgact acaacgggct
    18481 gctgcggtcc tgcctgcggc ggccggagga cttcgaacgg gtggcgcgcg agttctgcga
    18541 ggaccaggtc gcggacggcg tccgctacgc cgaggtcacc ttcaccgcgg cggcgcacgg
    18601 cgaacggctc ggcgagccgg acatgccgct ggtgtccgtc ctcaaaggac tctcggccgg
    18661 ttccgccgaa cacgggctcc actggcgggt actcctggac cactcccgcc gccggtccgt
    18721 cgaacgcgcc cggctcaccc tcgacctcgc ccgccggtac gtccaggacg gggtgttcgc
    18781 gatcggcctc gccggggagg agaagtaccc gctcgcgccc ttcgcgggaa tctgtgacga
    18841 ggccgcggag gccgggctgc gcctgatcca ccacgcaggg gaggacgccg gaccggccag
    18901 catccgcgag gcgctcgaac tcgggcacag cgagcggatc ggccacggca tccggatcct
    18961 ggaggacgtc gcgctggtcg ccgaagtgcg ggaacgcggc atcgcgctgg aggtctgccc
    19021 gtcctcgaac gtgacgctcg ggctcgtgcc gtcgttcgag gagcacccgc tcccccggct
    19081 ggtcgacgcc gggctcgtgg tcactctcag caccgacgtc ccctcggtca ccaggaccac
    19141 gctcaccgac gagttcctgc gtacgcggga ggcgttcgcc tacgacgacc tcgcgctcgc
    19201 cggtctcgcc agggcctccg tcgacgcgtc cttcgcgacc gcggaactca agcgcgcgat
    19261 gcaccaggag atcgacgcct ggctccgctg acgccggagg ggtggcccgg ctcacccggg
    19321 aggcgggctc cacaagatct ccacatccgt cacgtaccgt ggagccggtg accgcttcgt
    19381 ccccttcgac cctggatctc atggaccagt ggcaaccacc gcccaagaga cgcggcccgc
    19441 gcggctgcgt gatgctcgcg ctcctggtcg tgggtgcctt ggtggccggt gccgtctggg
    19501 tcgtggtcag cctcaacgac cgtgagccgg tgccggtgaa gccggagttc gtggtccccg
    19561 cgctcaagcc cgcaccgcgg tcggcgatcc ccggcgacgc cgggccgctg cccgcggagc
    19621 ccgcgaagga cgcctggatc gcgaaggtgt cggagaacac ggacatcccc cgacgtccgc
    19681 ttcgggcgta cgtgaacgcg gccgaaaaag cgcccgcacg ctgcgacatc acctgggcga
    19741 ccatcgccgg gatcgggcgg accgagtccc agcacgcccg gcacgacggt tcccgtgccg
    19801 gcgaggacgg catcgtgacg ccgccgatca tcggcatccc cctcgacggc tcgcccggtg
    19861 tgctggcggt cgtcgacacc gacaagggcg ctctcgacgg cgacgcgaag tgggatcgcg
    19921 ccgtcgggcc gatgcagttc ttacccgcca cctggaagcg gtacggcgtc cgcgcgagcg
    19981 gtgacggtgc cgcgccggac ccgcagaaca tcgacgacgc cgcgatgacg acggcgcggt
    20041 acatgtgcgc gcggggcggc gacctcggca agcccgccgg ctggtggtcc gcggtgctga
    20101 cctacaacaa ctccgcccag tacgggcagg aagtgttcag caacgccgac gcctacggga
    20161 aagcggctct gaagccctaa gcgggcaaaa gccgggtgac cagtttggtc agctggtgca
    20221 cgttccggca ttcgtgcatc tcgacgacct ccgcgtaggc gtgcgcctcg gagtcgccgg
    20281 tggaccacag cgccgtccgt tcggggttga gccagtacgt atgccgtgcc gcggaagcga
    20341 ttccgcgcac ggcggccaga ttcgggtcgc cgccgttggt ccgcgcgtcg ccgaggatca
    20401 gcatggacgt cttgggtccc acggcgtccg cgtagcgctc ggcgaattcg cccagcgcgt
    20461 tcccgtaatc gctgtgcccg tcccagcggg tgagttcggc gtcggcgagg atgcgcgcgc
    20521 cgaggtcctc cgggtcggcg gcgccggtgt cgacgaggtg cgtgatctcg tcgcacgcgt
    20581 cgatgaacgc gaacacccgc accttgctga actggtcccg caacgcctgg acgagcagca
    20641 tggtgaagtt cgcgaacccg gccaccgaac ccgacatgtc gcacagcagc acgatttccg
    20701 gccttcccgg ccggtgccgc cggtacgacg gccgcatcgg gacaccgccg gtggacagcg
    20761 agcggcgcaa cgtccggcgc aggtcgatct gcccgcgcgc gtgccgccgt cgccgggcgg
    20821 ccagcttggt ggcgagcttg cgggacaacg gctgcacgac ccggcggagt tcggcgagtt
    20881 gcgcgcggct cgcgagcagg aagtcgacgc ggtcggcggc gggcgggacg gcgtggcgcg
    20941 aaacccgttc cctgccacgg acttccgcca cccggcggcg tgcttcggtg cgcaccaggc
    21001 cgcggaaacc ttcgacccgg cggcggacg
//
