LOCUS       NZ_CP017780            21137 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Amycolatopsis sp. BJA-103 chromosome, complete genome.
ACCESSION   NZ_CP017780
VERSION     NZ_CP017780.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. BJA-103
  ORGANISM  Amycolatopsis sp. BJA-103
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Isolation and identification of a potent feather degrading rare
            actinomycete Amycolatosis sp. BJA-103 isolated from the rhizomes of
            Valeriana jatamansi Jones with abundant antibiotic biosynthetic
            potential
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9488490)
  AUTHORS   Ke,X. and Jia,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2016) College of Life Sciences, Northwest A&F
            Unversity, No.22 Xinong Road, YangLing, Shaanxi 712100, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2016
            Assembly Method                   :: SMRT v. 2.3.0
            Assembly Name :: version 2.3.0 of the PacBio Single Molecule Real
            Time
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:58:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,631
            CDSs (total)                      :: 8,562
            Genes (coding)                    :: 8,496
            CDSs (with protein)               :: 8,496
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 66
            CDSs (without protein)            :: 66
            Pseudo Genes (ambiguous residues) :: 0 of 66
            Pseudo Genes (frameshifted)       :: 31 of 66
            Pseudo Genes (incomplete)         :: 47 of 66
            Pseudo Genes (internal stop)      :: 2 of 66
            Pseudo Genes (multiple problems)  :: 13 of 66
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:43:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3101116
            Orig. end                         :: 3122253
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017780.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from B415, College of Life
            Sciences, Northwest A&F Unversity.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="14"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11137](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11137)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(2142..3188)
                     /locus_tag="BKN51_RS13400"
                     /old_locus_tag="BKN51_13155"
     CDS             complement(2142..3188)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020669819.1"
                     /locus_tag="BKN51_RS13400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13155"
                     /product="hypothetical protein"
                     /protein_id="WP_101607956.1"
                     /transl_table=11
                     /translation="MLKRALFSVFLAVALLVSQTPGAQARTADQLAVSDADRNLVFMLM
                     LYDPRATVRAAATTAYIDDAQDEAITRFLATDYAFAVELARESDATNLDFVRRVLETYL
                     PEFAPEVHAAAQRVVNGTPGEREAFVRVGYAAAQERDRLAREASGEAKRAIIEADRAFV
                     RDLGQTDPGEQVRAAAAFAVRPGAGDGALVEFFAYGWAGGGRLDLDVHRARAADNDITW
                     RMTATRLAKEARAAEKAALEASEEAAEQLRAQAAQAWRTAADRTGPARSAWAEAAELSA
                     RQAENWRAVAAAAQAATGPNWQAIGGPAVGNEQQWSAEHDWAGERAQYWQDLLAEAQAG
                     ETRMTRTA"
     misc_feature    complement(3232..3246)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.06"
                     /tool="antismash"
     gene            complement(3442..3975)
                     /locus_tag="BKN51_RS13405"
                     /old_locus_tag="BKN51_13160"
     CDS             complement(3442..3975)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635611.1"
                     /locus_tag="BKN51_RS13405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13160"
                     /product="hypothetical protein"
                     /protein_id="WP_101607957.1"
                     /transl_table=11
                     /translation="MAPPRDEVVAKWIEELTAFTELYRAAEIEGSAEAVSHAGWHAGAR
                     LGPDTASGRLLAYNESGVEAECVFREGERTLFNIMSTGYGNDTTERGFAVWSSRPGVLG
                     AIDAGVTRLEVADTDGMVVPADIVAHTFAVDVDLGPAPQNMDEVFAPWEPPELTVRVYG
                     EGDTLRYEGPLLIS"
     gene            4291..4548
                     /locus_tag="BKN51_RS13410"
                     /old_locus_tag="BKN51_13165"
     CDS             4291..4548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032717.1"
                     /locus_tag="BKN51_RS13410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13165"
                     /product="hypothetical protein"
                     /protein_id="WP_101607958.1"
                     /transl_table=11
                     /translation="MTAQRTITDEIGEIGVWLMGEFGGRVPAAVISRVLNASRRDLEGR
                     IDPEELGEMFHTLCRFRLQRILASDQRITIKIPAPASREW"
     gene            complement(4574..6025)
                     /locus_tag="BKN51_RS13415"
                     /old_locus_tag="BKN51_13170"
     CDS             complement(4574..6025)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159844.1"
                     /locus_tag="BKN51_RS13415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13170"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_101607959.1"
                     /sec_met_domain="Aldedh (E-value: 2e-151, bitscore: 503.6,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIANDKLFIGGEWTTPSDPTPLDIVSPHDQSLLGRVVQALPADID
                     RAVAAARTAFDEGPWPRTPPEERIAVLRRLNALREARAAEIAELISAENGSALWFTRAG
                     QPGVGRLAVSYLKAAEEFGWEETLTPSDPSAPFRSIVRREPIGVVSAIIPWNSPFSASM
                     AKIVPALLAGNTVVLKVSPENSLSMSLLADLLAEAGLPSGVISVLPADRETSEYLVKHP
                     GVDKIAFTGSTAAGRRIASLAGAQLKRVSLELGGKSAAVILPGAVLEDAIAGLRFGSLL
                     NNGEACIAQTRILAPRSRYDEVVDGLKEMMESLVVGDPADEKTFIGPMVRPGQQQRVRD
                     YIEIGAAEGARLVTGGPEIPDGLEKGNYVTPTLFADVDSAMRIAQEEIFGPVLVVLPYD
                     DEDDAIRIANDSEYGLSGGVWSADEEHALAVARRMRTGTVTVNGAPIGFDGPFGGFKAS
                     GVGREYGAAGLAQYVELKTVTVPNS"
     gene            6105..6641
                     /locus_tag="BKN51_RS13420"
                     /old_locus_tag="BKN51_13175"
     CDS             6105..6641
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635614.1"
                     /locus_tag="BKN51_RS13420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13175"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_168214326.1"
                     /transl_table=11
                     /translation="MRADAARNLEAVLTTGARMLASDPSTSIGAIAAEAGVDRRTVYRR
                     FASREDLLAAIYDSRLTAVEEVVRGARLTESAVPVALHRYVEGIIEVNRAWPVELTRMR
                     TEPSIQERRSRLTADVDSFLRRATDEGFLRADVPDGWASRLLIQLLHLASREDLDAPRA
                     ADLLVGTFLDGVGIH"
     misc_feature    complement(6660..6674)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            6707..7804
                     /locus_tag="BKN51_RS13425"
                     /old_locus_tag="BKN51_13180"
     CDS             6707..7804
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334395.1"
                     /locus_tag="BKN51_RS13425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13180"
                     /product="ionic transporter y4hA"
                     /protein_id="WP_101607961.1"
                     /transl_table=11
                     /translation="MAATRRRFPVSWTTVTPVLAIVVLALSWGRDLGPVPVAIVALALG
                     ATVLAAVHHAEVVAHRVGEPFGSLVLAIAVTVIEVALIVTMMSSGGPEAGTLARDTVFA
                     AVMITTNGIVGISVMVGARRYGETHFNPEGSGGALATVATLAAVTLVLPTFTFSTPGPA
                     FSSTQLTFAAVASLLLYGLFVLTQTVRHRDFFLPVDTDGTVKEEEHAEPPTNKAALTSL
                     GLLLVALVAVVGLAKVESPAIEAGVSAAGFPQSFVGVVIALLVLLPETLAATRAARRDR
                     MQTSLNLAYGSAIASIGLTIPTIALASIWLDGPLLLGLGATHIVLLALTIAVSVLTVVP
                     GRATRLQGGVHLVLLASFLVLAVNP"
     gene            7859..9850
                     /gene="ligA"
                     /locus_tag="BKN51_RS13430"
                     /old_locus_tag="BKN51_13185"
     CDS             7859..9850
                     /EC_number="6.5.1.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="ligA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635616.1"
                     /locus_tag="BKN51_RS13430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13185"
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="WP_101607962.1"
                     /transl_table=11
                     /translation="MNARDRIQELADQIVVLRDAYYRGSPKVADADYDAVEDELRGLIE
                     ANPGLAPDPNPLDQVGAPAVLHAPIRHSRPMLSLEKATKPEQVSAFFTRFPGQSVVVMP
                     KLDGLSLALVYENGRLARAITRGDGTTGDDVTPLVRALTDGVPEKVDAPGRVEVRGEAV
                     MLRSTFAAYNKVHPDKPLINPRNAAAGTLRAKDAATVSERRLRFFAFDLSTEPDSAETD
                     LDGALRTLGFTAADMRHCEDAEAAQAVITTIEEQRNDLDYDLDGAVLRLADRDAYAAAG
                     TRSSSPRGALAFKFAAEEKTTVLADVVWDVGKTGKIAPVAWLEPVFVGGTTVTRATLAN
                     QEVIRARGIKIGDTVLVRRAGDVIPFVAGVLDASKRTGEEREIVPPSVCPSCEEPLTEQ
                     GNSRELFCTNVACPAQTVRRLIHWASRAAADIDAIGGVWIERLAEAGILEHPSDFYRLT
                     KETLLEFDRIGDISATRMIESIDASRAVGLRRALIGLAIPMASEGTAARLCRAGFGSLE
                     DVAAAGEEGLVAVDDIGPKVAASLIEHLTRLRPELERLREVGVSLDVREEDLPPVVVAG
                     APLEGKTVVVTGSISDPRSGEKVPRPTFQRLCEKAGATTATSVSANTDMLITGADVGAS
                     KIAKAEKLEVEVVDQGVIWQQLIAAGVV"
     gene            complement(10001..11137)
                     /locus_tag="BKN51_RS13435"
                     /old_locus_tag="BKN51_13190"
     CDS             complement(10001..11137)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159832.1"
                     /locus_tag="BKN51_RS13435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13190"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_101607963.1"
                     /sec_met_domain="T1TS (E-value: 9.2e-54, bitscore: 182.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHGALATLLAGPSGLGTSAARLAARLAQPAAISPAAEEAPPPE
                     GPGLDPAYAFRPWGDGSAPPLYCPVTERINEPLAEEVDRRLALWAGECGFDEEECEQIG
                     TAGFGRLVMLAHPDCEDPDRLLISAKLNAAWWAADDLYADDTSLGAVPAELPPKLALAM
                     AAMDPVPSLGEFSRDLDETLRSDRVLIALNSGIEYLRASGTAAQVQRVCYSTFAMFVSW
                     TAYAAWRHSGKYPPAWEYLAARQHDSFYTSMTLIDVLGGYELTSNLYYDPRVREAAIQA
                     GTAAVLVNDVHSVTKDLEDESPPCNAVLLIADDRKCSIAEATAITVELHNDVVRDFQAA
                     HEKLSAVPSLELQRFMRGLRGWMGGGFEWHSTSPRYRP"
     gene            complement(11164..12027)
                     /locus_tag="BKN51_RS13440"
                     /old_locus_tag="BKN51_13195"
     CDS             complement(11164..12027)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032723.1"
                     /locus_tag="BKN51_RS13440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13195"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_101607964.1"
                     /transl_table=11
                     /translation="MTIARTPVPAKVLRTEYQKSVASYWNKEKDPVNLRLGDVDGLYHH
                     HYGVGEVDWSVLEGPESTRDERIIAEMHRLETAQADVLLDHLGDVKPEDRLLDAGCGRG
                     GSSIMANARFGCHVDGISISEKQVEFANHQAEIRGVADRVRYHFRNMLDTGFETGSRKG
                     IWNNESTMYVDLHELFAEHARQLEFGGRYVTITGCYNDVTGGRSKAVAQIDQHYTCNIH
                     PRSQYFKAMTANDLVPISVVDLTADTIPYWELRAKSSVATGIEGPFLDAYREGSFHYLL
                     IAADRV"
     gene            complement(12081..13469)
                     /locus_tag="BKN51_RS13445"
                     /old_locus_tag="BKN51_13200"
     CDS             complement(12081..13469)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016334401.1"
                     /locus_tag="BKN51_RS13445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13200"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_101607965.1"
                     /transl_table=11
                     /translation="MTATTPEADRRLSLGPAAARNLATTTKTRPQMQSITPRWLLKMLP
                     WVEATGGSFRVNRRLTYAVGDGRVSFTNVGTEIRVVPQELAELALLRGFDDEDTLTALA
                     DRFVQHEYRPGETIVSHGSPLDEVVLVAHGKVAKVAPGEYGTEAAIGSMADGDHFGDEM
                     LAGIDRNWPFTVKAVTPVTVLTLRADDFADLNGRSEAMRRHVQDMLAHKGKPQNAKGES
                     EIGMSSGHDGEPLLPGTFVDYEISPREYDLAVAQTALRVHTRVTDLYNGPMNQFDEQLR
                     LTVAALRERQEHDLINNREFGLLHNADLKSRFQTRSGPPTPDDMDELVSRRRKTKFFLA
                     HPRAIAAFGRECTRRSLYPEGTTVDGKVVAAWRGVPILPCDKIPVTEAGTSSILAMRTG
                     LEDNGVIGLHQTGLPDEYEPGLNVRFDGISEKAVATYLVSTYYSAAVLVPDALGVLENV
                     EVAR"
     gene            complement(13466..14887)
                     /locus_tag="BKN51_RS13450"
                     /old_locus_tag="BKN51_13205"
     CDS             complement(13466..14887)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159827.1"
                     /locus_tag="BKN51_RS13450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13205"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_101607966.1"
                     /transl_table=11
                     /translation="MTVTESDTSAEGVQGPGNPQLSLGRAAARNLATTTKSVPQMQGIS
                     SRWLLKMLEWVQVNGGAYRVNRRLNYAVGDGRVTFSKAGTEVSVIPAELGELKPLKGYD
                     DEEVLDELARRFEQQEVSAGDVLVEFGHRADRVYLIAHGKITKTGPGHYGDETALGVVK
                     DGDYFGAQALVADDGIWEFTAKAATACTVLTLTRQAFERVLEQSESLQAQIEQASQDSG
                     RANDFGEAEIDISSGHDGEPLLPGTFVDYETSPREYELSVAQTVLRVHSRVSDLYNQPM
                     DQTEQQLRLTIEALRERQEHEMINNADFGLLNNADFTQRIPTRSGPPTPDDFDDLLALV
                     WKDPGFFLAHPRTIAAFSRECSKRGIYPTGADLGGHKVPSWRGVPILPCNKIPVSQTST
                     SSVLLMRTGEKNQGVIGLRQIGLPDEYEPGLNVRFMGISEQAIISYLVSTYYSAAVLVP
                     DALAVLEAAELGREG"
     misc_feature    complement(14917..14931)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            15359..15697
                     /locus_tag="BKN51_RS13455"
                     /old_locus_tag="BKN51_13210"
     CDS             15359..15697
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159818.1"
                     /locus_tag="BKN51_RS13455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13210"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_101607967.1"
                     /transl_table=11
                     /translation="MLTCETQGAALARLGRALADPNRCRILVALLEGVSYPGQLAGQLG
                     LSRSNVSNHLACLRGCGLVVATYEGRQVRYALADAHLARALRELVQVVLAVDTAEPCVD
                     DAGIEVLR"
     gene            15694..16347
                     /locus_tag="BKN51_RS13460"
                     /old_locus_tag="BKN51_13215"
     CDS             15694..16347
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005159817.1"
                     /locus_tag="BKN51_RS13460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13215"
                     /product="cation transporter"
                     /protein_id="WP_174720411.1"
                     /transl_table=11
                     /translation="MSVESGSCADGCCATTSTVDEDRRVVLSRRVRLLVAATITYNVIE
                     AVIAISAGTIASSTALIGFGLDSVIEVASATAVAWQFSGKDPEARERTALKVIAVSFFA
                     LAAYVTVESVRTLFGADPAEHSTVGIVLAAVSLLVMPFLSHAQRRAGRELGSASAVADS
                     KQTLLCTYLSGVLLVGLLLNSLFGWYWADPLVALVIAAVAIKEGREAWRGEHCC"
     gene            16358..16969
                     /locus_tag="BKN51_RS13465"
                     /old_locus_tag="BKN51_13220"
     CDS             16358..16969
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032728.1"
                     /locus_tag="BKN51_RS13465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13220"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_101607969.1"
                     /transl_table=11
                     /translation="MTPPARWNRYWDGKSRNYDREMQFLDRKLFGDSRAWACGQATGDV
                     LEVAVGTGLNLRLYPGDVTLTGIDLSDGMLAIARDRAERLGHPVTLRRADAHDLPFDAG
                     SFDTVVCTLGLCAIPDDGKALREMARVLRPGGLLILLDHIASSSRAVRGLQWLTEKITV
                     PMAGEHFLRRPFDKIGDLGLTVEHRDRFKLGLVERLVARK"
     misc_feature    complement(16989..17003)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            17013..17471
                     /locus_tag="BKN51_RS13470"
                     /old_locus_tag="BKN51_13225"
     CDS             17013..17471
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BKN51_RS13470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BKN51_13225"
                     /product="hypothetical protein"
                     /protein_id="WP_101607970.1"
                     /transl_table=11
                     /translation="MTYPQQPPVWQQYPAPPPKKSPKTGLVFGVAAAALVVAVGGIAVT
                     VALATGDNAISGTPLSGSAPEVDPDPFSAQAGDCISADEDAGTNGKFSASAVRVHCTDD
                     SANYTVIAQLASSTGSDCKEVPGYEYGNPVVYDFKSGSSRELCVMPRN"
     gene            complement(17476..18522)
                     /locus_tag="BKN51_RS13475"
                     /old_locus_tag="BKN51_13230"
     CDS             complement(17476..18522)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032730.1"
                     /locus_tag="BKN51_RS13475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13230"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_101613203.1"
                     /transl_table=11
                     /translation="MKPVEPMLDHGFFGPGSVTWKVWGHVTAAVTGLQRSVVVEELDPA
                     LIAAVDKTGANYARPRTRYDRTVRYFAMVAFADSQKVSQAADVLVKVHAKAIGVEPVSG
                     NHYDANDPHSQLWILLTGWHSVLKAYELYGGGRLTPAEENRYWEECAIAAEFQTCDPAD
                     VPRTRDGVREYFERMRPRLAVSEAARKMMDHLLTAKVVLPPAPRVLAPALWVVNWFLRA
                     GTIATMPRWMRKLSGFTQPQVVDLLVRPVLRLGYGVVDRNPRLKLAVARLLAPSAVPVV
                     APYVLGVPPLSEEVLTPAEARRRYGYDRPADAHRDIRAKQHQRVFGAGQAPSEDGLIES
                     QAVLGSLS"
     misc_feature    18558..18573
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            18618..19259
                     /locus_tag="BKN51_RS13480"
                     /old_locus_tag="BKN51_13235"
     CDS             18618..19259
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032731.1"
                     /locus_tag="BKN51_RS13480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13235"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_101607971.1"
                     /transl_table=11
                     /translation="MTSTTPRKRRAYAARVPAEQRRTQVLDAALHLVVTRGHNATTMDA
                     VAEQAGVTKPVVYGQFRSRNELLAALLRREQEAALRQLLEVLPGDPGRFLTEDAPEFIA
                     RTLADFLNAVQETPDRWYCIVMPMADMPAEFHAAREAARAIALDRAESLTRWLLEAVGA
                     PAELDPEIVAHTVTALFEMAARLVLTDPGRYRPERFVGAIRAAVGLVQPR"
     gene            complement(19490..20083)
                     /locus_tag="BKN51_RS13485"
                     /old_locus_tag="BKN51_13240"
     CDS             complement(19490..20083)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005457846.1"
                     /locus_tag="BKN51_RS13485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13240"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_101607972.1"
                     /transl_table=11
                     /translation="MTEVLGRRERKKAATRQKIADTALRLFLERGYDAVGIREVAAEAD
                     VAVTTLFSHFASKEALVFERDANFEQSLARAVTGRAPHEPLISALRREMHAMVRHCTAD
                     GAAPIWRMIDGSPALREYEESMRLRHAESLAAAIAADPGLSHSATACRTIARFVVDAHS
                     LGREAADPEAAVDEIFRMIEAAWEVVSPSEQPAG"
     gene            20154..21047
                     /locus_tag="BKN51_RS13490"
                     /old_locus_tag="BKN51_13245"
     CDS             20154..21047
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (14-182). E-value: 4.3e-34.
                     Score: 110.0. Matches aSDomain:
                     nrpspksdomains_BKN51_RS13490_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550955.1"
                     /locus_tag="BKN51_RS13490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BKN51_13245"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_101607973.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-08, bitscore: 33.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVIFTEFGGPEVLQLVDAEDPHAGPGQVRIAVRAAGVNPFDWR
                     VREGQVLGAHPTTLPSGVGLDAAGVVDEVGEGVTDAEVGDRVFGEGLNTYAEFAVMTVW
                     ARMPEGLTFEEAAGYPSVAETALRLIREVGVRSGETLLVSGASGGVGSAVVQIARERGI
                     TVIGTAGAANQDYLRGLGAIATTYGEGWAGRVRELGQVDAALDLAGSGVIPELVELTGD
                     PLKVLSIADLGAPEFGVRFSGVAGSVPDALAEASDLISRGKLHIPVEKSYTLADAATAH
                     VDSHAGHTRGRRVIVI"
     misc_feature    complement(20158..20172)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.0"
                     /tool="antismash"
     aSDomain        20196..20699
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BKN51_RS13490_PKS_ER.1"
                     /evalue="4.30E-34"
                     /label="BKN51_RS13490_PKS_ER.1"
                     /locus_tag="BKN51_RS13490"
                     /protein_end="182"
                     /protein_start="14"
                     /score="110.0"
                     /tool="antismash"
                     /translation="LQLVDAEDPHAGPGQVRIAVRAAGVNPFDWRVREGQVLGAHPTTL
                     PSGVGLDAAGVVDEVGEGVTDAEVGDRVFGEGLNTYAEFAVMTVWARMPEGLTFEEAAG
                     YPSVAETALRLIREVGVRSGETLLVSGASGGVGSAVVQIARERGITVIGTAGAANQDYL
                     RGLGA"
     CDS_motif       20565..20627
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BKN51_RS13490_0001"
                     /evalue="2.40E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="BKN51_RS13490"
                     /protein_end="158"
                     /protein_start="137"
                     /score="16.9"
                     /tool="antismash"
                     /translation="GETLLVSGASGGVGSAVVQIA"
ORIGIN
        1 ccgctcgtgc cgcctccgcg gccttcactt cgaagaccgt cgcttcagcc gccttggcgt
       61 tcgacagctc cgccagggca tgggtggccg cggcagccga ctcggcctcc cgcgcccact
      121 tgtcggcctc tttggcgtgg aaggtcgctt gatccgccgc ggcacgggcc cgcgcagcgg
      181 ccctggtcgc ctcggtggcg tgagtacgcg cgctgacggc cgcaccggtg gccgcgtcgg
      241 ccgcggtacg cgcctctctc gcggcctgct ccgcttgtcc cgcttcggtc cgggcctggg
      301 cggccgcgtt cttcgcttct tgttcgtatc cggtgcctgc cgcggcggcc gcacccgccg
      361 ccagtgcctg cgccttcgct tccgctgcct gcctcgcctg ttcagcggag aaggccttcc
      421 cacgcgcctc ggtggccttc cggtcttcgg cgaccgcgtt gtccgccgcc tgctgcgccg
      481 tccggtcctg ctcttcggca cggccccgcg cgtcatgggc gaggcctgcc tgccgttcgg
      541 cctcgccgcg tttggtcctg gccgtcgtcg cgtcacgctc cgccgcggcg cgctcgttgg
      601 ccgcgttcgc ccgttcctgc tccgcgatcc ggcgctggtc tgcggccttg cgctgctcgt
      661 cgtccgcccg cagccgggcc tcatgtgcct tcgccgcttc ccgccacgcc gcctgttcgg
      721 cctgctccgc ctcgatgcgg gcctgtttgg tccgagcggc ggcctcttgc gccgcgaccg
      781 cctgtacccg cgccgcttcg gccaccctgg ccgccgaacg agcgtgctct tcggcgtggg
      841 tacgccattt cgcggcttcc tcggcgtgcc gttccgcctt ctcctgcgcg ttccgcgcgg
      901 catcgaccgc ggcggtggcg tcgatggcct gtcgagcggt ctgggcggca ccggcggccg
      961 cctccgaggc cgcggccatc cccctggcca tctcggccca cttcgcgccg tagggcaggt
     1021 tcacctcgac gaggacgttc gcctcgaccg tcgcggtggc cgaggcctgc tgtgcgtcgg
     1081 tcaccgcgcg ctgcgccgca tcgagttgcc gggtcgcttc ccgtttcact tcgtcgaacg
     1141 cagacggcgg atgaatgccg cctgcctcgt tggccgccag gatctgtgcg gcgcgacggg
     1201 cctcgttggc cgcggcgatc atcccattgg ccgcccactc caaggcccgc acgccgttgc
     1261 cgtgcgcgat gagcagattc ttccgtgcgg tcgatgcccg agcggcccgc ttggccagat
     1321 cggtgagctg ctcggcggcc ttggcgcgtt cctcctgttc acgcagatat gcttcgcgag
     1381 cgtctgcgtc ctttttggaa gccaccagat atccgccgtt gaggaattcg gcgatcgccg
     1441 catcccctcg ggacaacgcg agctgggcgg ccgtacgtac ttcgagaccg cccacgccgg
     1501 ccaacatctc ggtccgggag cgcagcagcg cggccctcgc ccgcacgtcc gccaccactt
     1561 gttcgtcccg ggagcgctcg atctccgcgc cgtaggcgac gaagttcgaa cgatcggcgt
     1621 ccgaaccggc gaggacccgg ctgaccccgg cttcgaggta cggtccgcca gtgcccgcca
     1681 tcgcctcgac cttggcgcgg tcttgccggg cggcctcctg tttgcgtgcc gccgcccggg
     1741 ccatggcgtt ttcgtggccg gtcgcaagga actcgaagat cccggcttcg ccctgggcca
     1801 gtgccgcagt cgcggcttcc ctgacctcga cgtcctcgtg cagctcggcg ttgtccgcga
     1861 cgagctgccg cagcctgggg tcgcccagat tcacctggcc ggacgtgccg tcccaatccc
     1921 gccaccacga ctcgggcatc ggtcgcggct cacccgactg cacgtccacg gcggacgcca
     1981 tcgaccaacc ggctcgcggg gctccggagg cgggctggac caacccggcg agcacggcca
     2041 cggacaacaa caccaggaac gatcttcggc tcgaccgcgt caacgcacgc atcgtcaact
     2101 cccgttcagg aagaaagaga aagaactccg gctcggtgga ttcaggcggt gcgcgtcatc
     2161 cgggtttccc cggcctgcgc ttcggcgagg aggtcctgcc agtactgagc acgttcgccc
     2221 gcccagtcgt gttccgcgga ccattgctgc tcattgccca ccgcggggcc accgatcgcc
     2281 tgccagttcg gtccggtcgc ggcttgggcg gcggcggcca ccgcacgcca gttttcggcc
     2341 tgtcgcgcgg acagttcggc cgcttcggcc catgccgagc gcgccgggcc ggtccggtcg
     2401 gccgccgtac gccacgcttg agcggcctgt gccctgagct gttccgcggc ctcttccgaa
     2461 gcctccagcg ccgctttctc cgccgcacgg gcttccttcg ccaaccgcgt ggcggtcatc
     2521 ctccacgtga tgtcgttgtc cgcagcgcgt gcccggtgaa cgtccaggtc gaggcgtccc
     2581 ccaccggccc agccgtaggc gaagaactcc accagggcgc cgtcaccggc gccgggtcgc
     2641 accgcgaaag ccgcggccgc gcggacctgc tcgccgggat cggtctgccc gaggtcgcgg
     2701 acgaacgccc gatcggcctc gatgatcgcc cgtttcgcct ctccggacgc ttcccgtgcc
     2761 agtcgatccc gttcctgcgc ggccgcgtac ccgacgcgca cgaaagcctc gcgctctccc
     2821 ggggtcccat tgaccacccg ttgtgcggcg gcatgcactt ccggcgcgaa ttcgggcaaa
     2881 tacgtctcga gcacccgccg cacgaaatcg agattcgtcg cgtcgctttc cctggccagt
     2941 tccacggcga aggcataatc cgtcgccaag aaccgggtga tcgcctcgtc ctgcgcgtcg
     3001 tcgatgtacg cggtggtggc cgcggcccgg acggtggccc tcgggtcgta cagcatcagc
     3061 atgaagacca gattccggtc cgcgtcactg accgccagct ggtcagcggt ccgcgcctgc
     3121 gctcccggcg tctgcgaaac cagcagcgcg acggcaagga acaccgaaaa gagagctctc
     3181 ttgagcaccg gtcaatcccc ccagatcagt gagcaatcct ccagtcgcag acataatcag
     3241 agaataagta tcggcgcaag aatgcaaatg gcggaattac ccacagggat cgccacatat
     3301 cagatcttga tcaacaggcg cttttcgaaa cggaatcaat ccgggaagat ccacttcgat
     3361 acgaattcct cagggttcga gatctccggt acacagacgg gtgtcctcga ggggccgcag
     3421 cccctcgagg acaccggtcg gtcaactgat cagcagcgga ccttcgtacc gcaacgtgtc
     3481 gccctcgccg tacacccgga ccgtcaactc cggcggctcc cacggcgcga acacctcgtc
     3541 catgttctgg ggcgccggcc ccaggtccac atcgacggcg aaggtgtggg ccacgatgtc
     3601 ggccgggacg accatgccgt ccgtgtcggc cacctccagc cgggtcacgc cggcatcgat
     3661 cgcgccgagc acgcccggcc gcgaactcca caccgcgaac cctcgctcgg tggtgtcgtt
     3721 cccgtacccg gtgctcatga tgttgaacag cgtgcgctct ccctcacgga agacgcactc
     3781 cgcctcgaca cccgactcgt tgtaggccag caaccgcccg ctcgcggtgt ccggcccgag
     3841 cctggccccg gcgtgccacc ccgcgtgtga caccgcctcc gccgaccctt cgatctccgc
     3901 cgcccggtaa agctcggtga aggccgtcag ttcctcgatc cacttcgcga ctacttcatc
     3961 ccttggtggg gccactacgc gtgcgccctc ctctctgact gtccacaatg gtcattaccg
     4021 aggttgacat acgcggatgc cgatcgcatc ggggtttccc cggagatcac ccgggccgct
     4081 gcacggttcc gtgcaaccga cggcgaaccc ccggtgctca cgctgacgcc atcgagcggg
     4141 cacggaacgt ggacgttcgg ggccttgggg aacagtcgat tgcgccgagt agagcaatct
     4201 cgcggattct ccgtcatggg gtttcccatc gcacgtcgga gtgtcgccgg gacaaacccg
     4261 gcggcactcc gacgcagagg ggcaaggctg atgaccgcgc agcgcacgat cacggacgag
     4321 atcggcgaaa tcggtgtctg gctgatgggc gagttcggcg gccgcgtgcc cgctgccgtg
     4381 atcagccgcg tgctcaacgc gagcaggcgc gacctcgagg gccgcatcga ccctgaggaa
     4441 ctgggcgaga tgttccatac cctctgccgg ttccggcttc agcggatctt ggcgtcggac
     4501 cagcggatca cgatcaagat ccccgcgcct gcgtctcgtg agtggtaaag acggttctaa
     4561 ccgtctttac cactcacgag ttcggcacgg tgacggtctt gagctccacg tactgggcaa
     4621 gaccggcggc accgtattca cggccgacgc cgctggcctt gaacccgccg aacgggccgt
     4681 cgaagccgat cggcgccccg ttgacggtga ccgtcccggt gcgcatccgc cgggcgaccg
     4741 cgagcgcgtg ctcttcgtcg gccgaccaga caccgccgga gagcccgtac tcggaatcgt
     4801 tcgcgatgcg gatcgcgtcg tcctcgtcgt cgtaaggcag gacgacgagc accggcccga
     4861 agatctcctc ctgggcgatc cgcatcgcgc tgtcgacgtc ggcgaacaac gtcggcgtga
     4921 cgtagttgcc cttctcgagg ccgtccggga tctcgggacc tccggtgacc agccgcgcgc
     4981 cctcggcggc gccgatctcg atgtagtcgc gcacccgttg ctgctgaccg ggccgcacca
     5041 tcgggccgat gaaggtcttc tcgtcggccg ggtcgccgac gacgagagac tccatcatct
     5101 ccttgagtcc gtcgacgacc tcgtcgtacc ggctacgggg cgcgaggatc cgcgtctgcg
     5161 cgatgcacgc ctcgccgttg ttgagcagcg acccgaacct cagcccggcg atcgcgtcct
     5221 ccagcacggc gccaggcagg atcacggccg cggatttgcc gcctagttcc aggctgaccc
     5281 gcttgagttg cgcacccgcc agcgacgcga tccggcgccc cgcggcggtc gagccggtga
     5341 acgcgatctt gtcgactccg gggtgtttca ccaggtactc gctggtctcg cggtccgcag
     5401 gcagcacgct gatcaccccg gacggcagcc cggcctccgc cagcaggtcc gcgagcaggc
     5461 tcatgctgag cgagttctcc ggcgagacct tgaggacgac cgtgttcccc gcgagcagcg
     5521 ccgggacgat cttggccatc gacgccgaga acggtgagtt ccacgggatg atcgcggaca
     5581 ccacgccgat cggttcccgg cgcacgatcg aacggaacgg cgcggacggg tccgagggcg
     5641 tgagcgtctc ctcccagccg aactcctcgg ccgccttcag gtacgagacg gccagccgtc
     5701 ccactccggg ctgaccggcc cgcgtgaacc acagggccga gccgttctcg gccgagatca
     5761 gctcggcgat ctcggccgcg cgggcctccc tcaaggcgtt gagccgccga agaaccgcga
     5821 tccgttcctc cggcggggtc cgcggccacg gtccttcgtc gaaagcggtc ctggccgcgg
     5881 cgacggcacg gtcgatgtcg gcgggaaggg cctggacgac gcgccccagc aaggactggt
     5941 cgtgagggga cacgatgtcc agcggcgtcg gatcgctcgg cgtcgtccat tcgcctccga
     6001 tgaagagctt gtcgttcgcg atcaccgttc caccttcctt aaatgtcaca ccaacgtagc
     6061 acttattgca gttaacgaca caggtgtgtg atacattccc gaacgtgaga gctgatgcgg
     6121 cgcgcaatct cgaagcggtc ctgaccacgg gcgcgcggat gctggcgagc gacccatcga
     6181 cgagcatcgg cgcgatcgcc gccgaagccg gagtagaccg gcgcaccgtc tatcggcgct
     6241 tcgcctcccg tgaagacctt ttggcggcca tctacgactc ccggctgacc gcggtcgaag
     6301 aggtggtccg cggcgcccgg ctcaccgagt cggcggtccc cgtggctctg caccgttacg
     6361 tcgagggcat catcgaggtc aaccgcgcct ggccggtcga gctgacccgg atgcgcaccg
     6421 aaccgtccat ccaggagcgt cgaagccggc tcaccgccga cgtggactcg ttcctccggc
     6481 gcgccaccga cgaggggttc ctccgagcgg acgtcccgga cggctgggcg agccgtctgc
     6541 tgatccagct cctccatctc gcctcgcgcg aggacctgga cgccccgcgc gccgcagacc
     6601 tcctcgtcgg gacctttctg gacggtgtcg gcatccacta agaagttcgt caccctgtgc
     6661 cccacatgga ggggcgacgt cacgcagggt gtgcgaaagt gacgtcatgg ccgccacgcg
     6721 cagacgattc cccgtgtcct ggaccaccgt caccccggtc ctcgccatcg tcgtcttggc
     6781 tctgagctgg ggccgcgatc tgggcccggt gccggtggcc atcgtcgcgc tcgccctggg
     6841 cgcgacggtg ctggccgcgg tgcatcacgc cgaagtggtc gcgcaccgcg tcggcgaacc
     6901 cttcggctcg ttggtgctgg cgatcgcggt cacggtcatc gaggtcgcgc tgatcgtcac
     6961 gatgatgtcc tcgggcggcc ccgaggctgg gacgctggcc cgcgacacgg tgttcgccgc
     7021 ggtgatgatc accacgaacg gcatcgtcgg catctcggtc atggtgggtg cccgccgcta
     7081 cggcgagacg cacttcaacc cggagggcag tggcggcgcc ctcgccaccg tggccaccct
     7141 cgccgccgtg accctcgtgc tgccgacgtt caccttcagc accccagggc ctgctttcag
     7201 cagcacgcag ctcacgttcg ccgccgtcgc gtcgctgctt ctctacggcc tcttcgtgct
     7261 cacccagacc gtgcgccatc gtgacttctt cctgccggtc gacaccgacg gcaccgtcaa
     7321 ggaggaagag cacgccgagc cgccgaccaa caaggccgcg ctgaccagcc tcggactgct
     7381 gctggtcgcg ctggtcgccg tcgtcggtct cgcgaaggtc gagtcgcccg ccatcgaggc
     7441 cggagtcagc gcggccggtt tcccgcagtc gttcgtcggt gtcgtcatcg cgctgctggt
     7501 gctgctgccc gaaaccctcg ccgcgacgcg ggccgcccgg cgcgaccgga tgcagaccag
     7561 cctcaacctc gcctacggtt cggcgatcgc gagcatcggg ctcaccatcc cgaccatcgc
     7621 gctggcgtcg atctggctgg acgggccgct gctgctgggc ctcggcgcga cccacatcgt
     7681 gctgctcgcg ctgacgatcg cggtcagcgt gctcaccgtc gtccccggcc gcgcgacccg
     7741 gctgcagggc ggtgtgcacc tggtgctgct ggcctcgttc ctggtcctcg ccgtcaaccc
     7801 gtgacgcgag gcctcttcgg acggtgttct gtcggtggtc acgggtaatc tctgccccgt
     7861 gaacgctcgg gaccgcatcc aagaactcgc cgatcagatc gtcgtccttc gcgacgccta
     7921 ctaccggggc tcgccgaagg tggccgatgc cgactacgac gcggtcgagg acgagctgcg
     7981 ggggctcatc gaggccaacc ccgggctggc ccccgatccg aatccgctgg atcaggtcgg
     8041 cgcgcccgcc gtgctgcacg cgcccatccg gcactcgcgc ccgatgttgt cgctggagaa
     8101 ggcgaccaaa cccgagcagg tctcggcgtt cttcacccgt tttcccggtc agtcggtggt
     8161 cgtcatgccg aagctggacg gcctgtcgct ggccctggtc tacgagaacg ggcggctcgc
     8221 gcgggcgatc acccgaggcg acggcaccac cggtgacgac gtgaccccgc tggtgcgggc
     8281 gctgaccgac ggcgtcccgg agaaggtcga cgcccccgga cgggtcgagg tgcgcggcga
     8341 ggccgtcatg ctgcggtcca ccttcgccgc gtacaacaag gtgcatccgg acaagccgct
     8401 gatcaacccg cgcaacgccg ccgcgggaac gctgcgcgcc aaggacgcgg ccaccgtctc
     8461 cgagcggcgc ctgcggttct tcgcgttcga cctgtccacc gaacccgaca gcgcggaaac
     8521 cgatctggac ggcgcgctgc ggacgctcgg cttcaccgcc gccgacatgc ggcactgcga
     8581 agacgcggaa gcggcgcaag ccgtcatcac gaccatcgag gagcagcgca acgacctcga
     8641 ctacgacctc gacggcgccg tgctgcgcct ggcggatcgc gacgcgtacg cggccgccgg
     8701 gacccggtcc agttcacccc gcggcgcgct ggcgttcaag ttcgccgccg aggagaagac
     8761 caccgtgctc gccgatgtgg tctgggatgt cggcaagacc ggcaagatcg ctcccgtggc
     8821 gtggctggag ccggtgttcg tcggcgggac caccgtcacc agggcgacac tggccaatca
     8881 ggaggtcatc cgcgcccgcg gcatcaagat cggcgacacc gtgctggtac gccgtgcagg
     8941 tgacgtgatc ccgttcgtgg cgggtgtctt ggatgcctcc aagcgcaccg gtgaggaacg
     9001 cgagatcgtg ccgccgtcgg tgtgcccgtc gtgcgaagaa ccgttgaccg aacagggcaa
     9061 cagccgggaa ctgttctgca ccaacgtcgc ctgccccgcg cagaccgtcc gccgtctgat
     9121 ccactgggct tcgcgagcgg ccgcggacat cgacgcgatc ggcggggtct ggatcgagcg
     9181 gctcgccgaa gccgggattc tcgaacaccc gtcggacttc taccggctca ccaaggaaac
     9241 gctgctggaa ttcgaccgta tcggtgacat ctccgccacc cgcatgatcg aatcgatcga
     9301 cgcgagccgc gccgtcggcc tgcgccgggc gctgatcggg ctggcgattc cgatggcttc
     9361 cgagggcacc gccgcgcgac tgtgccgggc ggggttcggt tcgttggagg acgtcgccgc
     9421 cgcgggcgaa gaaggcctcg tcgccgtgga cgacatcggc ccgaaggtcg ccgcgtccct
     9481 gatcgagcac ctcacgcggt tgcgccccga actcgagcgg ctgcgggagg tcggtgtctc
     9541 actggacgtg cgcgaggagg acctcccgcc ggtcgtcgtg gccggtgcgc cgctcgaagg
     9601 caagacggtc gtggtcaccg ggtcgatcag cgacccccgt tccggtgaaa aggtgccgcg
     9661 cccgaccttc cagcggttgt gcgagaaggc gggcgcgacc accgcgacgt cggtctcggc
     9721 gaacaccgac atgctcatca ccggtgccga cgtcggggcg agcaagatcg ccaaggccga
     9781 gaagctcgaa gtcgaggtcg tggaccaggg tgtgatctgg cagcagctga tcgccgcggg
     9841 cgtcgtctag gcgtagatct cgtgagcagt gtcgcgaaag cgccgcttga agtacgtgat
     9901 ggcccccttc cttgcgtcta gcgcaaggaa gggggccatc acgtacttgg gacaggcgtg
     9961 agggtcgagt ttcttcgact gagccgaggg aaggggccct tcacggccgg taccgcggac
    10021 tcgtcgagtg ccattcgaaa ccgccgccca tccacccccg caacccgcgc atgaaccgct
    10081 gcagttcgag agaaggcacc gcgctcagct tttcgtgcgc cgcctggaag tcccggacga
    10141 cgtcgttgtg cagctcgacg gtgatcgccg tggcctccgc gatcgagcac ttccggtcgt
    10201 cggcgatcaa caggaccgcg ttgcacggcg gcgactcgtc ctccagatcc ttggtgaccg
    10261 agtgcacgtc gttgacgagc acggccgccg tacccgcctg gatggccgcc tcacggaccc
    10321 gcgggtcgta gtagaggttc gacgtcagtt catagccgcc gaggacgtcg atcaacgtca
    10381 tcgacgtgta gaagctgtcg tgctgcctgg ccgcgagata ctcccaagcc ggcgggtact
    10441 tcccgctgtg gcgccaagcc gcgtaggcgg tccagctcac gaacatcgcg aacgtcgaat
    10501 agcagactcg ctgcacctgc gcggccgtcc cggacgcccg cagatactcg atacccgaat
    10561 tcagtgcgat cagaacccgg tcgctccgca gggtttcgtc gaggtcgcgg ctgaactccc
    10621 ccaacgacgg caccgggtcc atggcggcca tcgccagcgc gagcttcggc ggcagctccg
    10681 ccgggacggc gccgagggag gtgtcgtcgg cgtagaggtc gtcggccgcc caccaggcgg
    10741 cgttgagctt cgccgagatc agcagcctgt cgggatcctc gcagtccggg tgggcgagca
    10801 tgacgagcct gccgaagccc gccgtcccga tctgctcgca ttcctcctcg tcgaacccgc
    10861 actcccccgc ccacaaggcc aaccgccggt cgacctcctc ggcgagcggt tcgttgatcc
    10921 gttcggtgac ggggcagtac agcggcggtg ccgacccgtc accccacggc cggaacgcgt
    10981 acgccggatc gagaccgggt ccctccggcg gcggagcctc ctccgccgcc ggagaaatcg
    11041 cggccggttg agccagcctg gccgccagcc gggcggcgga cgtgcccaat ccgctcggac
    11101 cggccagcaa cgtggccagc gcaccgtgtt ccgtcatcac ttcactccgg tggtctcgcg
    11161 ggatcagacg cggtccgcgg cgatgagcag gtagtggaag ctgccttccc ggtaggcgtc
    11221 gaggaacggc ccctcgatcc cggtcgccac cgacgacttc gcccgcagtt cccagtacgg
    11281 gatcgtgtcc gccgtgaggt ccaccaccga gatcggcacc aggtcgttcg ccgtcatcgc
    11341 cttgaagtac tggctgcgcg gatggatgtt gcaggtgtag tgctggtcga tctgcgcgac
    11401 ggccttggac cggccaccgg tcacgtcgtt gtagcacccg gtgatggtga cgtagcggcc
    11461 gccgaactcc agctgccgcg cgtgctcggc gaagagctcg tggaggtcca cgtacatggt
    11521 gctttcgttg ttccagatgc ccttgcgcga gccggtttcg aagccggtgt cgagcatgtt
    11581 gcggaagtgg tagcgcaccc ggtcggcgac gcccctgatc tccgcttggt ggttggcgaa
    11641 ctcgacctgc ttctccgaga tcgagatccc gtcgacgtga cagccgaacc gtgcgttggc
    11701 catgatgctc gagccgccgc gcccgcagcc ggcgtcgagg agccggtcct ccggtttgac
    11761 gtcgccgagg tgatcgagca ggacgtccgc ctgcgcggtc tccaggcggt gcatttcggc
    11821 gatgatccgc tcgtcgcggg tgctctcggg cccctccagt accgaccagt cgacctcgcc
    11881 caccccgtag tggtggtggt acagcccgtc cacgtcaccc agccgcaggt tgaccgggtc
    11941 cttctccttg ttccagtacg acgccaccga cttctggtat tcggtgcgca gcaccttggc
    12001 gggaacgggg gtgcgggcga tggtcacgtg ggtggtcctt tctggagcat tggtgttcgt
    12061 tgtcgtggca ggactgatgg tcaccgcgcg acctcgacgt tctccagaac gccgagcgcg
    12121 tcgggcacga gaacggcggc cgagtagtag gtgctgacca ggtaggtcgc gaccgccttc
    12181 tcgctgatgc cgtcgaaacg cacgttcagg cccggctcgt attcgtcggg cagaccggtc
    12241 tggtgcaggc cgatcacgcc gttgtcctcc aacccggtcc gcatggcgag gatcgaggac
    12301 gtgccggcct cggtgaccgg gatcttgtcg cagggcagga tcggcacccc gcgccacgcg
    12361 gcgaccacct tgccgtcgac cgtggtgcct tccgggtaga ggctgcggcg cgtgcattcc
    12421 ctgccgaacg cggcgatcgc gcgcggatgg gcgaggaaga acttcgtctt gcggcggcgg
    12481 ctgacgagtt cgtccatgtc gtcgggcgtc ggcgggccgg accgggtctg gaaccgcgat
    12541 ttgaggtctg cgttgtgcag cagcccgaat tcgcggttgt tgatcaggtc gtgttcctgc
    12601 cgctcccgca gtgccgccac ggtcagccgg agctgctcgt cgaactgatt catcggcccg
    12661 ttgtagagat cggtcacgcg tgtgtgcacg cgcagcgccg tctgggcgac ggcgaggtcg
    12721 tactcgcgcg gcgagatctc gtagtcgacg aaggtgcccg gcagcagcgg ctccccgtca
    12781 tgccccgacg acatcccgat ctcggactca cccttggcgt tctgcggctt tcccttgtgc
    12841 gccagcatgt cctgcacgtg acggcgcatc gcctccgacc ggccgttgag gtcggcgaag
    12901 tcgtcggcgc gcagggtcag caccgtcacc ggggtgacgg ccttgacggt gaacggccag
    12961 ttgcgatcga tgccggcgag catttcgtca ccgaagtggt cgccgtcggc catgctgccg
    13021 atggcggctt cggtgccgta ctcgcccggc gccaccttgg cgaccttgcc gtgcgcgacc
    13081 agcacgacct cgtcgagcgg ggaaccgtgg ctgacgatcg tctcgccggg ccggtactcg
    13141 tgctgcacga accggtcggc gagcgcggtg agcgtgtcct cgtcgtcgaa accgcgcagc
    13201 agtgccagtt ccgcgagttc ctgcgggacg accctgatct cggtgccgac gttggtgaag
    13261 ctcacccggc cgtcgccgac agcataggtc aggcgccggt tgacccggaa ggagccaccg
    13321 gtcgcctcga cccagggcag catcttcagc agccagcgcg gcgtgatgct ctgcatctgc
    13381 ggccgcgtct tggtggtcgt cgccaggttg cgcgcggcgg cgggaccgag actgagccgc
    13441 cggtcggcct ccggcgtcgt ggcggtcatc cttcgcggcc gagttcggcg gcttcgagca
    13501 cggcgagcgc gtccggcacg agcacggcgg cggagtagta cgtgctgacg aggtaggaga
    13561 tgatggcttg ctcggagatc cccatgaagc ggacgttcag gccgggctcg tactcgtcgg
    13621 gcaggccgat ctgacgcagg ccgatcacgc cctggttctt ctcgccggtg cgcatcagca
    13681 gcacggaact ggtgctggtc tggctcaccg ggatcttgtt gcacggcagg atcgggaccc
    13741 cgcgccagga cggcaccttg tgcccgccga ggtcggcgcc ggtcgggtag ataccgcgtt
    13801 tgctgcactc gcggctgaac gcggcgatcg tgcgcggatg cgcgaggaag aagccggggt
    13861 ccttccacac cagggcgagc aggtcgtcga agtcgtccgg agtgggcgga ccggagcgtg
    13921 tcgggatgcg ctgggtgaag tcggcgttgt tgagcaggcc gaagtccgcg ttgttgatca
    13981 tttcgtgctc ttggcgctcg cgcagcgcct cgatggtcag gcggagctgc tgctcggtct
    14041 ggtccatcgg ctggttgtag aggtcggaga cgcggctgtg aacccgcagc acggtctggg
    14101 cgacgctcag ttcgtattcc cgcggcgagg tctcgtagtc gacgaaggtg cccggcagca
    14161 gcggctcgcc gtcgtggccg gaggagatgt cgatctcggc ttcaccgaag tcgttggcac
    14221 gaccggaatc ctgcgacgcc tgctcgatct gcgcctgcag cgattcggac tgctccagca
    14281 cgcgctcgaa ggcctggcgg gtcagggtca gcacggtgca ggccgtggcc gccttcgcgg
    14341 tgaactccca gatcccgtcg tcggcgacga gggcctgcgc accgaagtag tcaccgtcct
    14401 tgaccacacc gagcgcggtc tcgtcaccgt agtgaccggg gccggtcttg gtgatcttgc
    14461 cgtgggcgat gaggtagacc cggtcggccc ggtgcccgaa ctcgacgagc acgtcgcccg
    14521 ccgatacctc ctgctgctcg aagcggcggg cgagttcgtc gagcacctct tcgtcgtcgt
    14581 accccttgag cggcttcagt tcccccagct ccgccgggat cacgctcact tcggtgccgg
    14641 ccttcgagaa cgtcacccgg ccgtcgccga ccgcgtaatt gagccgccgg ttgacccggt
    14701 aggcgccacc gttgacctga acccattcga gcatcttcag cagccaccgg gacgaaattc
    14761 cctgcatctg cggaacggat ttggtcgttg tcgccaggtt tcgcgcggcg gcccggccca
    14821 aactcagctg cggatttccc ggcccctgga caccttcggc ggaagtgtcc gattcggtca
    14881 cggtcacagc aaggtccacc cttcaatagt cgcgtgagaa aacaagatcc accaaccacg
    14941 gtgtgccgac tgtgccccga ggtgcggccc ccgcagggat caacatagca aggcggtttg
    15001 cccgcacaag cgcactttcg ggtagtgaga aaaggccacc cgaatgccga tttccccatt
    15061 atgcgagaag gcttccatca ccattactcg gcgctttaac gcacccacac aatcggtcca
    15121 gcgattgttc tgaggtgtta tgcgccgccg ccccgggact cccgggcgta cgcgttatgc
    15181 ggccgttgga ggggtgcgcc gagtcctttc gggtcacccg cgcgcccgtg ttcggcgatg
    15241 gcttgacaga cagcgacgaa acagagggtc gcatccggac actccgtcgt gtcaagcagc
    15301 cgttccaacc ctgcccaccc gttgctgaca tgtcagcgag cgctgtactg ttctacccgt
    15361 gctgacgtgt gaaacccagg gcgccgcgct cgcccggctc ggtcgcgccc tcgccgaccc
    15421 gaaccggtgc aggatcctgg tcgctctgct cgaaggcgtg agctatcccg gccagctggc
    15481 cgggcaactc ggcctgagcc gctccaatgt gtccaaccac ctcgcgtgcc tgcgagggtg
    15541 cgggctggtc gtggcgactt acgagggcag gcaggtccgc tatgcgctgg cggacgccca
    15601 cctcgcccgc gcgctgcggg aactggtgca ggtcgtgctc gccgtcgaca cggcggagcc
    15661 ctgtgtggac gacgccggta tagaggtgct ccggtgagcg tggagagcgg atcctgcgcg
    15721 gacggctgct gcgccacgac atccacagtg gacgaggatc gccgcgtcgt gttgtcgcgc
    15781 cgggtccggc tcctggtcgc cgcgacgatc acctacaacg tcatcgaagc ggtcatcgcc
    15841 atctccgcgg gcaccatcgc ctcctcgacc gcgctgatcg gcttcggcct ggactcggtc
    15901 atcgaggtcg cttccgccac cgccgtcgcg tggcagttct ccggcaagga ccccgaagcc
    15961 cgcgaacgca ccgcgctcaa ggtcatcgcg gtgtccttct tcgcgctggc cgcctatgtg
    16021 accgtcgaat ccgtacgcac cctgttcggc gccgaccccg ccgagcactc caccgtcggg
    16081 atcgtgctcg cggcggtctc gctgctcgtg atgcccttcc tgtcccacgc ccagcgccgc
    16141 gccgggcgag aactcggctc cgcgagcgct gtcgccgatt cgaagcagac cttgctctgc
    16201 acctatcttt ccggtgtgct gctcgtcggg ttgctgctca acagcctctt cggctggtac
    16261 tgggccgatc cgctggtcgc cctcgtcatc gccgccgtcg cgatcaagga aggccgcgaa
    16321 gcctggcgcg gtgagcactg ctgctgaaag gaacgccatg accccgcccg cgcgctggaa
    16381 ccgttactgg gacggcaaat cccggaacta cgaccgggag atgcagtttc tcgaccggaa
    16441 gctcttcggc gattcgcgag cgtgggcctg cggccaggcg accggcgacg tcctcgaggt
    16501 cgccgtcggg accggcctga atctgcggct ctatcccggc gacgtcacgc tcaccggcat
    16561 cgacctcagc gacggcatgc tcgccatcgc ccgtgaccgc gccgaacgcc tcggccaccc
    16621 ggtgacgctg aggcgtgccg acgcgcacga cctgccgttc gacgccggtt cgttcgacac
    16681 cgtggtctgc accctgggac tttgcgccat cccggacgac ggcaaggcgt tgcgggaaat
    16741 ggccagggtc ctgcggcccg gcggcctgct catcctgctc gatcacatcg cgagttcgtc
    16801 gcgtgccgtc cgcggcctgc aatggctcac cgaaaagatc accgtgccga tggcgggcga
    16861 gcacttcctg cggcgcccgt tcgacaagat cggcgacctc ggcctgacgg tggagcaccg
    16921 ggaccggttc aagctcgggt tggtggaacg gctcgtcgcc cgcaagtgaa ctctgtcatc
    16981 ggaatttcat cgacgccgtc gatcctgatg acgtgaccta cccccagcag ccgcccgtct
    17041 ggcagcagta ccccgctccg ccgccgaaga agtccccgaa aacggggctg gtcttcggag
    17101 tcgcggcagc cgctctcgtc gtcgccgtcg gagggatcgc ggtgaccgtg gcgctcgcga
    17161 ccggtgacaa cgccatcagt ggcactcccc tcagcggcag cgcccccgag gtcgatcccg
    17221 acccgttctc cgcacaggcc ggagactgca tctcggccga cgaagacgcc gggacgaacg
    17281 gcaagttcag cgccagcgcg gtccgggtcc actgcacgga cgattcggcc aactacacgg
    17341 tgatcgcgca gctggcgtcc agtaccggct cggactgcaa ggaagtgccc ggctacgagt
    17401 acggcaaccc ggtcgtctac gacttcaagt cgggatcgtc cagggaactc tgcgtcatgc
    17461 cgaggaactg acggctcaag acagcgagcc cagaacggct tgggactcga tgagaccgtc
    17521 ttcgctgggt gcttgcccgg cgccgaacac ccgctggtgc tgcttcgccc ggatgtcacg
    17581 gtgggcgtcg gccggcctgt cgtagccgta acgccgtcgt gcttcggccg gggtcaagac
    17641 ctcttcggac agcggcggga cgccgagaac gtacggagcg acgaccggca ccgcggaggg
    17701 cgccagcagc cgggcgaccg ccagtttcag ccgcgggttg cgatcgacga cgccgtagcc
    17761 gagccgcagg accggccgga ccagcagatc gacgacctgc ggttgggtga acccgctcag
    17821 cttccgcatc cagcgcggca tggtcgcgat cgtcccggcg cgcaggaacc agttcacgac
    17881 ccagagggcc ggagccagca cccgcggcgc cggcggcaag accaccttcg ccgtcaacag
    17941 gtggtccatc atcttccggg ccgcttcact gaccgcgagc cggggacgca tccgctcgaa
    18001 gtactcccgc acgccatcgc gggtgcgggg aacgtccgcg gggtcgcagg tctggaattc
    18061 ggcggcgatc gcgcactcct cccaataccg gttctcctcg gctggcgtga gccggccccc
    18121 gccgtacagc tcgtaggcct tgagcaccga atgccagccg gtgagcagga tccacaactg
    18181 cgagtgcgga tcgttggcgt cgtagtggtt gccgctgacg ggctcgacgc cgatcgcctt
    18241 ggcatgcacc ttcaccagca cgtccgcggc ctgggaaacc ttctggctgt cggcgaacgc
    18301 gaccatggcg aaatagcgga ccgtgcggtc gtagcgggtg cgaggccgcg cgtagttcgc
    18361 accggtcttg tcgacggcgg cgatcagcgc cgggtcgagc tcctccacca cgacggaccg
    18421 ctgcagcccg gtgacggcgg ccgtcacatg cccccacacc ttccaggtga ccgatccagg
    18481 tccgaagaac ccgtggtcca gcatcggttc cactggtttc atcgccacgt cggcctcccg
    18541 ttcccgcaat taatactgat gcgtagcaat atcctacgct agagtagctt tgtccagagt
    18601 gcgcttgagg agggccgttg accagcacga caccgcggaa acgccgtgcc tacgccgcac
    18661 gcgtgccagc cgagcagcgc cgaacgcagg tgcttgacgc ggccctgcac ctggtggtca
    18721 cccgaggtca caacgccacg accatggacg cggtcgccga acaggccggc gtcacgaaac
    18781 cggtggttta cggccagttc cgcagccgga acgagctgct ggccgcactg ttgcggcgcg
    18841 agcaggaagc cgcgctccgg cagttgctcg aagtactgcc gggtgacccg ggccggttcc
    18901 tcaccgagga cgcccccgag ttcatcgcgc ggacgctcgc cgacttcctc aacgccgtcc
    18961 aggaaacgcc ggaccggtgg tactgcatcg tcatgccgat ggcggacatg cccgccgagt
    19021 tccacgccgc ccgcgaggcc gcgcgcgcca tcgccctcga ccgggcggaa tcgctgacgc
    19081 gatggctcct ggaagccgtc ggtgccccgg cggaactcga tccggaaatc gtcgcgcaca
    19141 ccgtcaccgc gctgttcgag atggccgcgc ggctcgtgct caccgacccc ggacggtacc
    19201 ggccggagcg gttcgtcggc gcgatccggg ctgcggtcgg tctcgtccag ccgcggtgat
    19261 atctgctgag ttctgggcag cttcacggac tcagtgatgc ccagcggcgg tgtcgcgaaa
    19321 gccactttcg cgacgtctga tgtcccgaaa gtggctttcg cgacacctga acggctggtg
    19381 tggccgcatg ccgagcgtga aggaatcggg acgttaagcg tcccaattcc ttcatcgtcg
    19441 cgggccgtgt ccaccggaac ccgaatcgcc actcacgacc accgcgacct cagcccgccg
    19501 gttgctccga aggactgaca acctcccacg ccgcctcgat catgcggaag atctcgtcca
    19561 ccgcggcttc cggatcggcc gcctcgcgac cgagcgaatg ggcatcgacc acgaaccgcg
    19621 cgatcgtccg gcaggccgtc gcggaatgcg agagaccagg atcggccgcg atcgccgccg
    19681 ccagcgactc cgcgtgccgc agcctcatcg attcctcgta ctcccgcaac gcgggcgatc
    19741 cgtcgatcat gcgccagatc ggcgcggcac cgtccgccgt gcaatgccgc accatcgcgt
    19801 gcatctcccg gcgcagcgcg gaaatgagcg gctcgtgcgg ggcgcgaccg gtcaccgccc
    19861 gcgcgaggct ctgctcgaaa ttcgcgtccc gctcgaacac caatgcctcc ttcgaggcga
    19921 agtgggagaa gagcgtggtg acggcgacgt cggcctccgc ggccacctcg cggatgccca
    19981 ccgcgtcgta tccgcgctcc agaaagagcc gcagggcggt gtcggcgatc ttctgtcggg
    20041 tcgcggcctt cttgcgctca cgacgtccga gaacctcggt catgctgcaa cgctatcaga
    20101 tccaaaacac caccagttct aaaacactaa ccgttagtgc tacggtcgag ctcatgaaga
    20161 aagtgatctt caccgagttc ggtggtccgg aagtcctgca gctcgtcgac gccgaggacc
    20221 cgcacgcggg ccccggccag gtacgcatcg cggtgcgagc cgcgggtgtg aaccccttcg
    20281 actggagggt tcgcgagggc caggtcctgg gcgcacatcc gacaacgctt ccctcagggg
    20341 tcgggctgga cgccgctgga gtggtcgacg aggtcggcga gggtgtcacg gatgccgagg
    20401 tcggcgaccg ggtgttcggc gagggcttga acacctatgc cgagttcgcc gtgatgacgg
    20461 tctgggccag gatgcccgag ggcctgacgt tcgaagaggc ggccggatat ccctccgtgg
    20521 cggagaccgc gctgcgcctc atccgcgaag tgggggtgcg atccggcgag acgctgctgg
    20581 tcagcggcgc gtccggcggg gtcggatcgg cggtagtgca gatcgcccgt gaacgcggca
    20641 tcacggtgat cggcacggcc ggggccgcga accaggatta cttgcgcggc ctgggcgcca
    20701 tcgccacgac gtacggcgag ggatgggcag gacgggtgcg agagctcggc caggtcgacg
    20761 cggctctcga cctcgcggga tcgggcgtga tccccgaact cgtcgagctc accggggatc
    20821 cgctgaaggt gctctccatc gccgatctcg gcgcaccgga gttcggtgtc cggttctccg
    20881 gcgtcgcggg cagcgtgccg gacgcgctcg ccgaggcctc ggacctcatt tcacggggca
    20941 agctccatat cccggtcgag aagtcgtaca cgctcgccga cgccgcgacc gcgcatgtcg
    21001 acagccatgc cggtcacacc cgcggacgcc gggtcatcgt catctgagcc tgtttcaggc
    21061 gggaaggatc acgacgccgt cgtcgtcgga gtagagcgtg tcgccgggag tgaaggtcac
    21121 tcccccgaag ccgacag
//
