LOCUS       NZ_CP024200            42994 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete
            sequence.
ACCESSION   NZ_CP024200
VERSION     NZ_CP024200.1
KEYWORDS    RefSeq.
SOURCE      Thalassospira marina
  ORGANISM  Thalassospira marina
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
            Thalassospiraceae; Thalassospira.
REFERENCE   1  (bases 1 to 908044)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Biodiversity and function of Thalassospira species in the
            particle-attached aromatic-hydrocarbon-degrading consortia from the
            surface seawater of the China South Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 908044)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2017) State Oceanic Administration, The Third
            Institute, Room 329, Daxue Road 184, Xiamen, Fujian 361005, P.R.
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3
            Genome Coverage                   :: 300
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002844375.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 04:06:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,760
            CDSs (total)                      :: 4,670
            Genes (coding)                    :: 4,656
            CDSs (with protein)               :: 4,656
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 2 of 14
            Pseudo Genes (incomplete)         :: 13 of 14
            Pseudo Genes (internal stop)      :: 4 of 14
            Pseudo Genes (multiple problems)  :: 4 of 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:03:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 651213
            Orig. end                         :: 694207
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024200.1.
            Bacteria and source DNA available from Dr. Zongze Shao; The Third
            Institute of State Oceanic Administration, Daxue Road 184#, Xiamen,
            Fujian, 3610015, China, Tel: 86-592-2195321.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..42994
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="2"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..42994
                     /SMILES="NC(CC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42994
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:22994](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..22994
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            817..1113
                     /locus_tag="CSC3H3_RS23105"
                     /old_locus_tag="CSC3H3_23040"
     CDS             817..1113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23040"
                     /product="hypothetical protein"
                     /protein_id="WP_101267078.1"
                     /transl_table=11
                     /translation="MAEQDNQTSPGGWEGALDNLFKYFGQAKDAVFSTYSDWQNTFGGE
                     NSASNSSNYASGENYDSGWSNPAAPVQTSNPNLGLYIGVGVALLAGMILITRK"
     gene            1123..1362
                     /locus_tag="CSC3H3_RS23110"
                     /old_locus_tag="CSC3H3_23045"
     CDS             1123..1362
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23045"
                     /product="hypothetical protein"
                     /protein_id="WP_133125813.1"
                     /transl_table=11
                     /translation="MFQGLMSMFGGGVGGGSGGSFIDTTSHATAGSTSESGHIYSYNNA
                     PFSVGGAAQTPVNMIASIVPWVVMGGVAWLLLKK"
     gene            1341..1757
                     /locus_tag="CSC3H3_RS23115"
                     /old_locus_tag="CSC3H3_23050"
     CDS             1341..1757
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23050"
                     /product="hypothetical protein"
                     /protein_id="WP_101267074.1"
                     /transl_table=11
                     /translation="MAAAEKIKIGLSQWDQTAAEHIRPVVLPESPLGLDGLRDDVANGR
                     AAVLAVQARGERIGTLLVRVEQGGDGKYFIIECANSHLAGVDLVKTCMPALEAWARKLG
                     CRALDVPTHRPGLVHKMKKQDYTVVKTVLRKVLT"
     gene            1754..2122
                     /locus_tag="CSC3H3_RS23120"
                     /old_locus_tag="CSC3H3_23055"
     CDS             1754..2122
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23055"
                     /product="hypothetical protein"
                     /protein_id="WP_101267072.1"
                     /transl_table=11
                     /translation="MSAGLSHSSSKSSTTSQNYDQRAGADNGSIAASGGATVTIDATSP
                     EAFDFAGDVAADVIDLTSVVVGGTFGALSDANKTVGAALEAVRKANTSDTANTLELLIK
                     IGVPVLGAAFILPAIFKK"
     gene            2131..2892
                     /locus_tag="CSC3H3_RS23125"
                     /old_locus_tag="CSC3H3_23060"
     CDS             2131..2892
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23060"
                     /product="hypothetical protein"
                     /protein_id="WP_101267071.1"
                     /transl_table=11
                     /translation="MTISRYQTYTGTIQPGELFTINRAGRSVTCFEASAGLEIVIDDGS
                     SSAFFAGVSVDFDYEFKRIQLLNPNDTPVTFQVATAMGKVNDNRLTASGILRVADPDSG
                     ASFSAVRAAAVDVANAVGELSKRANEAMQGSNMFMLYAPKHKIGTSFMYVQGVGSSPVT
                     LIDPAVNTSGVIIRTVVANNGAGNGASIFAGPSAPASWVDATKRQIYSFYSSYTQCYNH
                     CDPIHLPAGDGLYFLGNQGGSASLSVTWDYL"
     gene            2892..3167
                     /locus_tag="CSC3H3_RS23130"
                     /old_locus_tag="CSC3H3_23065"
     CDS             2892..3167
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23065"
                     /product="hypothetical protein"
                     /protein_id="WP_101267069.1"
                     /transl_table=11
                     /translation="MTNFEIMQLAYQLRGQGDDRPLADIVASVKADMAVFEPAAPGPGD
                     VVGGRVDQFPDGRKVTTEILGDGTEKVIKTEMIDLPKPEPEAAPNE"
     gene            3160..3672
                     /locus_tag="CSC3H3_RS23135"
                     /old_locus_tag="CSC3H3_23070"
     CDS             3160..3672
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011384823.1"
                     /locus_tag="CSC3H3_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23070"
                     /product="cell wall hydrolase"
                     /protein_id="WP_217351150.1"
                     /transl_table=11
                     /translation="MNKDALLLIGAGGLAYAAFMAARSGATEQSEYDVGSPSRVAQDVD
                     VLARTIWGEARGEGASGMQAVANVVMNRVAKQTWYGKTVVEVCKKPGQFTAWTKGDPNY
                     EPAHAVTTNNPAFAQALQIAGRAVAGTLPDITGGADHYFNPSVVLPSWAATMSHLIDIG
                     RHAFYRA"
     gene            3682..3951
                     /locus_tag="CSC3H3_RS23140"
                     /old_locus_tag="CSC3H3_23075"
     CDS             3682..3951
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23075"
                     /product="hypothetical protein"
                     /protein_id="WP_101267068.1"
                     /transl_table=11
                     /translation="MAVRYDPDLHAVEYAAGKWMACNALDQTACINMAEEVAAYENDPT
                     ATPGPFDGNDAPLVVNIEKTVINWPLIGLFLAGLLMAVAGLKRG"
     gene            4094..4243
                     /locus_tag="CSC3H3_RS24755"
     CDS             4094..4243
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS24755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157831998.1"
                     /transl_table=11
                     /translation="MPVLLIGVAIGAVIGGSGVWLASDAAQKVGNAALIGGGIYLAGKY
                     MKKW"
     gene            4378..4605
                     /locus_tag="CSC3H3_RS23145"
                     /old_locus_tag="CSC3H3_23080"
     CDS             4378..4605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23080"
                     /product="hypothetical protein"
                     /protein_id="WP_101267066.1"
                     /transl_table=11
                     /translation="MWEKVKDRFKEPSTYAGLAGVITSVGVLGKINEAPAIADTVSNAG
                     HAISQGDYATAIGVGLFGLLSIFIGEKGKR"
     gene            complement(4646..5104)
                     /locus_tag="CSC3H3_RS23150"
                     /old_locus_tag="CSC3H3_23085"
     CDS             complement(4646..5104)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23085"
                     /product="hypothetical protein"
                     /protein_id="WP_101286705.1"
                     /transl_table=11
                     /translation="MDRKLLDHLDKDALIKLADAYEDFARKARAKAEEIAERESNLINI
                     SARLNSLKAIGYEMSEMLNQYEQKQVEKILSNRHSCPPETVAHYYKMFLKANDAATVRA
                     RHLMVTKLAARGFNNRQIAKRTGLHEVSVSRILRPILRPGHLKQKKEA"
     gene            complement(5301..6002)
                     /locus_tag="CSC3H3_RS23155"
                     /old_locus_tag="CSC3H3_23090"
     CDS             complement(5301..6002)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (133-180). E-value: 2.2e-08. Score:
                     25.9. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23155_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="CSC3H3_RS23155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23090"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_101267063.1"
                     /transl_table=11
                     /translation="MNGDLGQPLPALYQVNGLCGHACLIPQIPETDLTAVGPDGLQIEL
                     PAQLARAVPKRKNEFLAGRLCCARALCDLGCNEISVPMGQYREPIWPQGIVGAISHDAD
                     IACAIVAKQSDYRGIGIDMEKMICQDNARRLFSQIATDTEQILLLSRFSQRVACTVLFS
                     AKEAVYKALFPVVDRFIDFKEARCVALERNLLSFVFTAEDLQSLTHYLQVSYEISETRV
                     LTLCLLKAECK"
     aSDomain        complement(5463..5603)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23155_ACPS.1"
                     /evalue="2.20E-08"
                     /label="CSC3H3_RS23155_ACPS.1"
                     /locus_tag="CSC3H3_RS23155"
                     /protein_end="180"
                     /protein_start="133"
                     /score="25.9"
                     /tool="antismash"
                     /translation="RLFSQIATDTEQILLLSRFSQRVACTVLFSAKEAVYKALFPVVDR
                     FI"
     misc_feature    complement(6066..6079)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.56"
                     /tool="antismash"
     misc_feature    complement(6072..6081)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.75"
                     /tool="antismash"
     misc_feature    complement(6294..6303)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     misc_feature    6310..6324
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.16"
                     /tool="antismash"
     gene            6411..8084
                     /gene="ilvD"
                     /locus_tag="CSC3H3_RS23160"
                     /old_locus_tag="CSC3H3_23095"
     CDS             6411..8084
                     /EC_number="4.2.1.9"
                     /GO_function="GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009099 - valine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011694362.1"
                     /locus_tag="CSC3H3_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23095"
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="WP_101286706.1"
                     /transl_table=11
                     /translation="MSYNRRSKTITEGIERSPNRAMFYALGYQEEDFDKPMIGVANGQS
                     TITPCNAGLQPLADAAIAAIRSAGANPQTFGVPTISDGMSMGTEGMKYSLVSREVIADC
                     IETTVQGQWMDGVLVIGGCDKNKPGGMIGIIRANIPAIYVYGGTIKPGNWKGEDLSITS
                     AFEAVGAFRAGHISEEDFKGIEKNACPTTGSCGGMYTANTMSSSFEALGMSLLGSSTMA
                     NPDAEKTVSAADSARVLVEAVKKNIRPSDIITRESVENAISLVMATGGSTNAVLHYLAI
                     CDAANIEWTLDDFERVRRKVPVFCDLKPSGKHMAVDLHRQGGVPQVLKQLLNAGLLNSE
                     CLTITGRTIGEELANVPDAPPSGQDVIRTIADPLYAEGHLAVLRGNLAQDGAVAKITGL
                     KSTAITGPARVFNDEQSALKAILSGEITAGDVLVLRYLGPKGGPGMPEMLAPTSAIVGQ
                     GLSDKVGLITDGRFSGGSWGLLVGHVTPEAYEGGTIALVEEGDMITIDANAGLLALNVD
                     QDEIERRRKNWHQPAPRYTRGVLSKFARLARPASKGAGTG"
     gene            8156..8800
                     /locus_tag="CSC3H3_RS23165"
                     /old_locus_tag="CSC3H3_23100"
     CDS             8156..8800
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013933.4"
                     /locus_tag="CSC3H3_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23100"
                     /product="LysE family translocator"
                     /protein_id="WP_101286707.1"
                     /transl_table=11
                     /translation="MSLSMPYDQASILTALATYIVGAASPGLGNMAIASTSVQSGRISG
                     FAVMFGVLAAGQTWALCAAAGLSSILLTMPSAMHLIGIVGGMYLVWLAFKTFKNKRTKN
                     RMEFAPHAGKSSTAHHFRKGFFIQILNPKAVLGWILIISIGVRPESPAYTPIIIVLCCL
                     ILGMIIFSSYVMLFSLIGTRPLPLGSMSLFRYAEPIVYFLAGSWLVVDSLK"
     gene            complement(8841..9770)
                     /locus_tag="CSC3H3_RS23170"
                     /old_locus_tag="CSC3H3_23105"
     CDS             complement(8841..9770)
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009523188.1"
                     /locus_tag="CSC3H3_RS23170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23105"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_101286708.1"
                     /transl_table=11
                     /translation="MNLRQLRYFVTLAEELHFSRAAERMNMTQPPFSQAIIALEQELGV
                     TLFNRTKRHVELTAVGEHWLECVRKVLDNAEQLPLLAKQIAHGEIGVLKFGFVSTAAYS
                     LLPRLVADFRLNCPDVKLDLEEMTSDLQAEAILNREIDVGMIIPAHQMFDHSLEYLPML
                     REPLVATVPKAWIENGRITCVNGKIRLAEIAQHPLIIFPRRIAPAFYDIITRYFSQSGY
                     KLEIGQEAIQMQTIISLVSSGLGIALVPEALRNLDRTGTCYVPLEGAPPFIETGLVWRR
                     EDSSPAVKRLINLAKPLAIPEKEVLNLA"
     misc_feature    10268..10281
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.28"
                     /tool="antismash"
     gene            10383..11378
                     /locus_tag="CSC3H3_RS23175"
                     /old_locus_tag="CSC3H3_23110"
     CDS             10383..11378
                     /EC_number="1.14.19.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta9_cd03505"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018331319.1"
                     /locus_tag="CSC3H3_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23110"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_217351149.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 3.3e-105,
                     bitscore: 348.8, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINQMDDVACQLFSENNPTDGPRKKVIDSPYLNKFQRIHFILFDV
                     APAIGAVATVVVSLTYKVTSLDLVLFAVMWLFSGLGISVGYHRLFTHRTFQASPTVRAL
                     LGIFGSMAGQGGVISWTAMHRRHHECGDQEGDLHSPNLSGPGWKGWIKGFVHAHFTWMY
                     AHSYPNVSHYAPDLLKDRVIVWVNRRYYTWIVLGLLIPTVIGGLYSQTWMGALTGFLWG
                     GAMRMFVVEQGIFSLNSLCHLIGKRRFKTHDQSTNIAWLSPFIFGESWHHNHHAFPGSA
                     SFGLAWYRIDPGYWFICLLSVLGQAWDIKIPTREQIQRRELPKAQASTRP"
     gene            11393..11680
                     /locus_tag="CSC3H3_RS23180"
                     /old_locus_tag="CSC3H3_23115"
     CDS             11393..11680
                     /NRPS_PKS="Domain: PP-binding (16-81). E-value: 1.5e-16.
                     Score: 52.4. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23180_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="CSC3H3_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23115"
                     /product="acyl carrier protein"
                     /protein_id="WP_157831999.1"
                     /sec_met_domain="PP-binding (E-value: 1e-12, bitscore:
                     43.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRILPEKNIDEAAIFQWLQTYICKTLDMNPASVGLHDNLDSLGM
                     DSAITTALAMDLEGWLNIEIPLSILFEADSLEQIAAGVSAEINRQQVSVE"
     aSDomain        11441..11635
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23180_PP-binding.1"
                     /evalue="1.50E-16"
                     /label="CSC3H3_RS23180_PP-binding.1"
                     /locus_tag="CSC3H3_RS23180"
                     /protein_end="81"
                     /protein_start="16"
                     /score="52.4"
                     /tool="antismash"
                     /translation="QWLQTYICKTLDMNPASVGLHDNLDSLGMDSAITTALAMDLEGWL
                     NIEIPLSILFEADSLEQIAA"
     gene            11677..12579
                     /locus_tag="CSC3H3_RS23185"
                     /old_locus_tag="CSC3H3_23120"
     CDS             11677..12579
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017308397.1"
                     /locus_tag="CSC3H3_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23120"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_101267053.1"
                     /transl_table=11
                     /translation="MNQSALKEVPAYGGSPSAIQFHYDVGREFYQLWLDDSMTYSSALW
                     SESDDDTLNAAQQRKIDYHLEQARARQASSLLDIGCGWGALVNKASSLPNLHKIVGLTL
                     SNDQADYVRGFGLPNLDIRLESWTEHHPTTHYDSIISVGAFEHFVKPEDSTAEKIATYR
                     DFFEKCAGWLSPGGWLSLQTFVYGTMKNEEASAFINHEIFPAADLPRLEQIMASVDGVM
                     ELTKLVNHRLHYARTYDMWARNLRRRRDEAVDLVGEAMTNKYERYLKQTSIGFYTGKIG
                     LLRMTFRPVDRSLSVLAKE"
     gene            12696..13961
                     /locus_tag="CSC3H3_RS23190"
                     /old_locus_tag="CSC3H3_23125"
     CDS             12696..13961
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CSC3H3_RS23190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23125"
                     /product="cytochrome P450"
                     /protein_id="WP_101286709.1"
                     /sec_met_domain="p450 (E-value: 7.9e-18, bitscore: 59.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLASSETATVLRRPNLVFNPLDPEFRKNPYPLYTRLRREAPVLRS
                     KGMLILSRYTDVLAVLKSRKFSVGLIPETVTTQASRIGFQDIAQMRRFLDTSIVFTDNP
                     EHMRLRRLVNQAFSKEAIYAFVPMIEQRIEKLLDIHSRKGHCEIIEDIAVPLPIDILCD
                     WMLIEEEARPQFSKKVHAVRQLLDPGMMSRSDFQAAAKGMRDLTGFLADHASRVGKIDD
                     GNLVSRLCNARFEEQGLSDEEIAFTCVMAFVAGTETTQSLIGNIVYTLLHNPDQFSSIL
                     NREGGVSAAIEEITRYETPLQFTKRQALEDCKVGDIEFLKGEQVLLCLGAANRDETVFE
                     DAAQLRLDRSGPKHVGFGFGMHSCLGALLAALQSEIFLQVLLSEYTGFRQISKTVDWQN
                     SSLILRGPSTLEIEFSRKQVIQ"
     gene            13958..14767
                     /locus_tag="CSC3H3_RS23195"
                     /old_locus_tag="CSC3H3_23130"
     CDS             13958..14767
                     /NRPS_PKS="Domain: Thioesterase (18-233). E-value: 7.4e-35.
                     Score: 113.4. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23195_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="CSC3H3_RS23195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23130"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_101267050.1"
                     /sec_met_domain="Thioesterase (E-value: 2.8e-31, bitscore:
                     104.9, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-07, bitscore:
                     27.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRFAEIFGNARPDTCVDLYAFHHAGGSRHSFAAWQNRFPRAINV
                     YRAQLPGRTPESYHFLPRKVAELIPDLAACFLRSRFGNINPFVFYGHSLGALVAFELTR
                     FLRQHSKTLPIGLIVSSRRAPQCPLVYSELCSLRDDLLLPKLEELGGVPAYLKAKPDEL
                     RRLLPVVRADLLLSDRYDYNEQPPFDLPVLATKGLHDPIMSLAELKAWSDQTTGKFECL
                     ELSGAHFFDSHGSTRLEKLLTETVIRWGNAPSPTPRKAILPLEETQC"
     aSDomain        14012..14656
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23195_Thioesterase.1"
                     /evalue="7.40E-35"
                     /label="CSC3H3_RS23195_Thioesterase.1"
                     /locus_tag="CSC3H3_RS23195"
                     /protein_end="233"
                     /protein_start="18"
                     /score="113.4"
                     /tool="antismash"
                     /translation="LYAFHHAGGSRHSFAAWQNRFPRAINVYRAQLPGRTPESYHFLPR
                     KVAELIPDLAACFLRSRFGNINPFVFYGHSLGALVAFELTRFLRQHSKTLPIGLIVSSR
                     RAPQCPLVYSELCSLRDDLLLPKLEELGGVPAYLKAKPDELRRLLPVVRADLLLSDRYD
                     YNEQPPFDLPVLATKGLHDPIMSLAELKAWSDQTTGKFECLELSGAHFFDSH"
     CDS_motif       14213..14269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23195_0001"
                     /evalue="3.40E-06"
                     /label="NRPS-te1"
                     /locus_tag="CSC3H3_RS23195"
                     /protein_end="104"
                     /protein_start="85"
                     /score="19.6"
                     /tool="antismash"
                     /translation="PFVFYGHSLGALVAFELTR"
     gene            14761..16551
                     /locus_tag="CSC3H3_RS23200"
                     /old_locus_tag="CSC3H3_23135"
     CDS             14761..16551
                     /NRPS_PKS="Domain: CAL_domain (48-492). E-value: 3e-125.
                     Score: 410.5. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23200_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="CSC3H3_RS23200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23135"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_101286710.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 2.7e-212, bitscore:
                     703.1, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-82, bitscore:
                     270.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNSVDVRTTETRTVPTMWNLLETYVATKADERAFIFLGPDNVEQ
                     EVLTYGALHRLAVAYGKQLRLATQPGDRAILMFPTGLSFIVSFLACHFAGVVPVPMVPL
                     KGQRLRDTVLAIAENCAATVVMTTSEQSEFLKSQLSVLPTYADAGFIGVNVDLECPPVT
                     SNDTPHPAQLSELAFIQYTSGSTSVPKGVMVSHANLAANLEMMTIAYENDQYSSYVGWA
                     PLYHDMGLIANVLEPFYLGTLCVLMAPNLFAHRPWLWLKAISDYQAHVSGGPNYAYDLC
                     IERAEEILEMGFDLSSWRVAFNSAEPVRAETLRRFTAAFMPLGFRPQTFYPCFGMAEAT
                     LLITGGTRAQVPLIENLSRTGLANGMAIEANDPKDTIEVVGCGQVLQQEDIRIVDPHST
                     IEKPDGEIGEIWVAGPHIPFGYWNNPVSSKETYQATIAGSIGPRFLRTGDLGFMQAGEL
                     YVTGRHKDLIIVRGHNVFPQDLEFIAERAAPGLKRNSGAAFAIEDPSDGQQTLCLVQEV
                     MLSQRYTIDVDDTIKAIRQAIMKETDITVHKIILVQPSSIPKTSSGKIRRAETKKRYID
                     GTLLVVQAQSSAATRQKATA"
     aSDomain        14905..16236
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23200_CAL_domain.1"
                     /evalue="3.00E-125"
                     /label="CSC3H3_RS23200_CAL_domain.1"
                     /locus_tag="CSC3H3_RS23200"
                     /protein_end="492"
                     /protein_start="48"
                     /score="410.5"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="TYGALHRLAVAYGKQLRLATQPGDRAILMFPTGLSFIVSFLACHF
                     AGVVPVPMVPLKGQRLRDTVLAIAENCAATVVMTTSEQSEFLKSQLSVLPTYADAGFIG
                     VNVDLECPPVTSNDTPHPAQLSELAFIQYTSGSTSVPKGVMVSHANLAANLEMMTIAYE
                     NDQYSSYVGWAPLYHDMGLIANVLEPFYLGTLCVLMAPNLFAHRPWLWLKAISDYQAHV
                     SGGPNYAYDLCIERAEEILEMGFDLSSWRVAFNSAEPVRAETLRRFTAAFMPLGFRPQT
                     FYPCFGMAEATLLITGGTRAQVPLIENLSRTGLANGMAIEANDPKDTIEVVGCGQVLQQ
                     EDIRIVDPHSTIEKPDGEIGEIWVAGPHIPFGYWNNPVSSKETYQATIAGSIGPRFLRT
                     GDLGFMQAGELYVTGRHKDLIIVRGHNVFPQDLEFIAERAAPGLK"
     CDS_motif       15289..15348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23200_0001"
                     /evalue="6.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="CSC3H3_RS23200"
                     /protein_end="196"
                     /protein_start="176"
                     /score="27.8"
                     /tool="antismash"
                     /translation="AFIQYTSGSTSVPKGVMVSH"
     CDS_motif       15967..16047
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23200_0002"
                     /evalue="5.00E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="CSC3H3_RS23200"
                     /protein_end="429"
                     /protein_start="402"
                     /score="25.3"
                     /tool="antismash"
                     /translation="PDGEIGEIWVAGPHIPFGYWNNPVSSK"
     CDS_motif       16141..16203
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23200_0003"
                     /evalue="8.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CSC3H3_RS23200"
                     /protein_end="481"
                     /protein_start="460"
                     /score="12.1"
                     /tool="antismash"
                     /translation="TGRHKDLIIVRGHNVFPQDLE"
     gene            16564..17010
                     /locus_tag="CSC3H3_RS23205"
                     /old_locus_tag="CSC3H3_23140"
     CDS             16564..17010
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011812072.1"
                     /locus_tag="CSC3H3_RS23205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23140"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_101286711.1"
                     /transl_table=11
                     /translation="MLVTAEHETAPKPAYSREEIEAIIAKTPFAAWAGAKLVSYKYGEV
                     EINLSMRRELTQHHGFGHGAIVGLLADSACAWAAASIVGDVVTAEYKLNFLAPAVGHTL
                     LAYGSVLGPAGRQTVCRADIYCQTQSRKILVATALATIAQVGRA"
     gene            17033..18058
                     /locus_tag="CSC3H3_RS23210"
                     /old_locus_tag="CSC3H3_23145"
     CDS             17033..18058
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (25-334). E-value: 4e-34. Score:
                     110.5. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23210_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1046: Dioxygenase TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="CSC3H3_RS23210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23145"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_101286712.1"
                     /sec_met_domain="TauD (E-value: 4.8e-33, bitscore: 110.5,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHKESFLSSDMPVIVWSPNEGQSLGVDDLSDYLASQKELILSRI
                     QEKGGILLRGFECIRTSDDYQKILDAVAPDLMEYIGGTSPRKVVNGRIMTATEIPGSYS
                     IPLHQEMSYTDNSPDLISFFCEIPPENGGETTIGDMRTITREISDDVRARFLAHNGIQL
                     CRNLPTPERVEMRPGVPKSWPEAMGTHIREEAENVAVKSGWRYEWLEDGSMQLWQEIRP
                     ATRKHPLTGEEVWFNQIQIFSPVLSLKWAREDGRDDAADRLSKALAEAPHLLDHMRYGD
                     GLQIDEEDALHIYDTLSANAVPLQWQRGDVLFLDNILVAHGRRKFSGQRRILTALIQHA
                     H"
     aSDomain        17108..18034
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23210_TauD.1"
                     /evalue="4.00E-34"
                     /label="CSC3H3_RS23210_TauD.1"
                     /locus_tag="CSC3H3_RS23210"
                     /protein_end="334"
                     /protein_start="25"
                     /score="110.5"
                     /tool="antismash"
                     /translation="GVDDLSDYLASQKELILSRIQEKGGILLRGFECIRTSDDYQKILD
                     AVAPDLMEYIGGTSPRKVVNGRIMTATEIPGSYSIPLHQEMSYTDNSPDLISFFCEIPP
                     ENGGETTIGDMRTITREISDDVRARFLAHNGIQLCRNLPTPERVEMRPGVPKSWPEAMG
                     THIREEAENVAVKSGWRYEWLEDGSMQLWQEIRPATRKHPLTGEEVWFNQIQIFSPVLS
                     LKWAREDGRDDAADRLSKALAEAPHLLDHMRYGDGLQIDEEDALHIYDTLSANAVPLQW
                     QRGDVLFLDNILVAHGRRKFSGQRRILT"
     gene            18091..18912
                     /locus_tag="CSC3H3_RS23215"
                     /old_locus_tag="CSC3H3_23150"
     CDS             18091..18912
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014457353.1"
                     /locus_tag="CSC3H3_RS23215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23150"
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_101286713.1"
                     /transl_table=11
                     /translation="MLNTSIKKFGSHHSVKQPGGSVETEVSLRIQLAEFYHLVAYLGWT
                     EAIFNHISLRLPGTDSHYLVNPFGLHYEEVTPENLVTVDLAGNLVGPSQYPANPAGFAL
                     HGAIHEVRHDMHCIAHTHTTAVSAIALKQDGFQHDDFYGAQLFEQVAYHDFEGVTLFAD
                     EKPRILKSLGDKNVLVMRNHGIAVGGRDVPRTFWTLFTAQRAAEIQCQAGMLPGRNSIL
                     SDQVRQRCSKVADDLAANASFAQKMFDGMVRKMRRHTGPLWPGDNGIDRLH"
     gene            18967..19878
                     /locus_tag="CSC3H3_RS23220"
                     /old_locus_tag="CSC3H3_23155"
     CDS             18967..19878
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04098.1"
                     /locus_tag="CSC3H3_RS23220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23155"
                     /product="Pnap_2097 family protein"
                     /protein_id="WP_101286714.1"
                     /transl_table=11
                     /translation="MLELQDRDRQCEPDVGLWTGCVEIALGMPHLALKGLSEAWVLKEL
                     GHLHWTLLARMAKRKFPDFQDAAGNVVYAAFRSVEVEGARFGLACENDILRITSTQCRI
                     SRTQIQSRHTLTINNEDDDAGIVIGVVTMVSVFVHRTNHTSNRSIARVEIQGLPPITGH
                     QLAPRHKWFDDNNLFTATEGNNRQVQSFLPCPSQDFNGAGFLYFANFSAFVDRAELNLD
                     PTFSRQAVTSQRHIKYHSNVDPGEPIRVEIMDLERSSSNWLHQCRISREKDGALMADII
                     TEKCIPEAIGPRRFSPSPQNTA"
     gene            20001..22994
                     /locus_tag="CSC3H3_RS23225"
                     /old_locus_tag="CSC3H3_23160"
     CDS             20001..22994
                     /NRPS_PKS="Domain: AMP-binding (22-385). E-value: 7.4e-49.
                     Score: 158.3. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23225_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (501-565). E-value: 1.7e-12.
                     Score: 39.5. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23225_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (627-870). E-value:
                     3.9e-25. Score: 80.4. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23225_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="CSC3H3_RS23225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23160"
                     /product="AMP-binding protein"
                     /protein_id="WP_172963486.1"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-50, bitscore:
                     166.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.8e-09, bitscore:
                     32.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.8e-27, bitscore:
                     91.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSEVMTRSVLESIHETAIAQDHLIAIEDGDRKLTYGQLWTCMCL
                     LGRQGLTTPHPGLIAICGRPSIETALGILAAFLSGDVAVPIDDRLPLSRREELAQWCDI
                     SYDKEEIVRITCDVAASPSMTCPPLSKIKREKRRPAYVAFTSGTTGVPKAIEGTMTGLD
                     HFIAWQSRLIGQWVQNPRVSWLTPLSFDVMYRDLLLPLNNRGTLVIPDSQQDFNIAAAW
                     NWLNDQKIDIAHVVPSIVGTWLNGRHSGPLSVKALFFAGEPLRQALISRLKENYVNRIY
                     NLYGPSESTMAKFCRLIDDKCTPTDSLYPVGMPIDHDVSYVLSKDQEIIIRSAYLTNGY
                     RQKDGTVAPFPSTSENCPEYHTGDRGRVIDGELYVLGRLDSQLKINGIRIEASEIESLA
                     ERYPGIRRTAAVKLAPPDSTVEIIVLFYQGDLERKDKMRKLLAEHLHPAVVPTAYLPIA
                     DFPLTLNGKIDRQKLKERAATEHLMDDPSSIKGTGTEECDNFEQRVQEIMSSILRYPCR
                     LDTDFLDIGGNSLMFGLITLELHSTFGLTMPQQEFYNSGTPRSVAAWLRQNGASVKVSA
                     SAPSEPTPTSNRSATGPWPLTPRQQTIHDIFHNELFGSGMNMILQVPVAADQMERVKAV
                     VSQIVAQNDCFHLNFRYRHGKLYQYLSPPDFRINDIDVIEAPCVDHDRLSAEFATRPFD
                     LAEEKPFRVRLLKDSAGTGRLLFLMYHLISDGMSQEYLRRDILDGISGNPIPLRNHYSP
                     SLQSEQRALSDRILPFWKEHLDGAMPTARFISPQHITNVSARCMTVALASDYDRLMGHL
                     RTLNSSIFPYLLSHFYRALAKHAAKADLIIRVTTHGRDKPELADVMGCIFSAVPVRLNC
                     AGWPTKQIVDYINNHLDTARMYQDLCFQKLAQALGEKQDIHLHPLTGISFTLDGFDITE
                     NMPASQSKSPQIETMNAKLPHELRAIARPYRNGCILKFVYRAKAFTDEDILAISSAMQG
                     AIAGELQR"
     aSDomain        20067..21155
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23225_AMP-binding.1"
                     /evalue="7.40E-49"
                     /label="CSC3H3_RS23225_AMP-binding.1"
                     /locus_tag="CSC3H3_RS23225"
                     /protein_end="385"
                     /protein_start="22"
                     /score="158.3"
                     /specificity="substrate consensus: Asp"
                     /tool="antismash"
                     /translation="HLIAIEDGDRKLTYGQLWTCMCLLGRQGLTTPHPGLIAICGRPSI
                     ETALGILAAFLSGDVAVPIDDRLPLSRREELAQWCDISYDKEEIVRITCDVAASPSMTC
                     PPLSKIKREKRRPAYVAFTSGTTGVPKAIEGTMTGLDHFIAWQSRLIGQWVQNPRVSWL
                     TPLSFDVMYRDLLLPLNNRGTLVIPDSQQDFNIAAAWNWLNDQKIDIAHVVPSIVGTWL
                     NGRHSGPLSVKALFFAGEPLRQALISRLKENYVNRIYNLYGPSESTMAKFCRLIDDKCT
                     PTDSLYPVGMPIDHDVSYVLSKDQEIIIRSAYLTNGYRQKDGTVAPFPSTSENCPEYHT
                     GDRGRVIDGELYVLGRLDSQLKI"
     aSModule        20067..21695
                     /complete
                     /domains="nrpspksdomains_CSC3H3_RS23225_AMP-binding.1"
                     /domains="nrpspksdomains_CSC3H3_RS23225_PP-binding.1"
                     /locus_tags="CSC3H3_RS23225"
                     /monomer_pairings="Asp -> Asp"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20418..20465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23225_0001"
                     /evalue="9.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="CSC3H3_RS23225"
                     /protein_end="155"
                     /protein_start="139"
                     /score="18.4"
                     /tool="antismash"
                     /translation="AYVAFTSGTTGVPKAI"
     CDS_motif       21126..21188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23225_0002"
                     /evalue="2.30E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="CSC3H3_RS23225"
                     /protein_end="396"
                     /protein_start="375"
                     /score="23.3"
                     /tool="antismash"
                     /translation="LGRLDSQLKINGIRIEASEIE"
     aSDomain        21504..21695
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23225_PP-binding.1"
                     /evalue="1.70E-12"
                     /label="CSC3H3_RS23225_PP-binding.1"
                     /locus_tag="CSC3H3_RS23225"
                     /protein_end="565"
                     /protein_start="501"
                     /score="39.5"
                     /tool="antismash"
                     /translation="QRVQEIMSSILRYPCRLDTDFLDIGGNSLMFGLITLELHSTFGLT
                     MPQQEFYNSGTPRSVAAWL"
     aSDomain        21882..22610
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23225_Condensation_LCL.
                     1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.90E-25"
                     /label="CSC3H3_RS23225_Condensation_LCL.1"
                     /locus_tag="CSC3H3_RS23225"
                     /protein_end="870"
                     /protein_start="627"
                     /score="80.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: YHLISDG"
                     /tool="antismash"
                     /translation="QMERVKAVVSQIVAQNDCFHLNFRYRHGKLYQYLSPPDFRINDID
                     VIEAPCVDHDRLSAEFATRPFDLAEEKPFRVRLLKDSAGTGRLLFLMYHLISDGMSQEY
                     LRRDILDGISGNPIPLRNHYSPSLQSEQRALSDRILPFWKEHLDGAMPTARFISPQHIT
                     NVSARCMTVALASDYDRLMGHLRTLNSSIFPYLLSHFYRALAKHAAKADLIIRVTTHGR
                     DKPELADVMGCIFSAVPVRLN"
     gene            23346..24287
                     /locus_tag="CSC3H3_RS23230"
                     /old_locus_tag="CSC3H3_23165"
     CDS             23346..24287
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005903058.1"
                     /locus_tag="CSC3H3_RS23230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23165"
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_281262546.1"
                     /transl_table=11
                     /translation="MILQLFPVWALLLSLLAFFMPGPFASLSTGIVPLLTVIMLAMGLT
                     LTAKDFANVAKSRKALVVGVILQFLIMPVAAWLVAKLFGFDDDLTVGMLLVGSVAGGTS
                     SNVMCYLAKGDTALSISMTATSTLIGVFLTPVLVAFLAGQSIDVPVQPMLMSLVKIVLV
                     PVIIGVVLNEIASKWVRKIEGIFPYISMFAILLIIAIVVALNADKVASVGLVVAFAVIL
                     HNAIGLSLGYGVTALLGFDRKICRTIAFEVGLQNSGLATALAMKFFTPVSALPGTLFSV
                     WHNISGSLLAGYWSRKPVDESLDEPVRKDAPA"
     gene            complement(24383..25561)
                     /locus_tag="CSC3H3_RS23235"
                     /old_locus_tag="CSC3H3_23170"
     CDS             complement(24383..25561)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018426845.1"
                     /locus_tag="CSC3H3_RS23235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23170"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_245881407.1"
                     /transl_table=11
                     /translation="MTDAFRKFRVTARIRESDVVTSFHFMPVDGGPLWQALPAQYLTLR
                     VPNGAGTVLKTYSLSGDVQQDNFHRISVKREGAPDGSDFPDGVGSCWLHDRVEEGHEID
                     IAPPRGGFVLDQASIRPVVLLAGGIGITPLLAMAKVLARSNRQVWIVHACENGDVQAFG
                     GELKALAAASDGRICLHVAYRQPTARDRAERGFDSEGLIDKALLQSLLPFDDYDVYMCG
                     PTAFMIAMYRLLRSLGIEKNRIAYEFFGAASSLEKLAEQPIQVPRAASRAPKAIAALVH
                     LTDPEAWAIPDASEPLANAGSGMAGNSGNIVRFAKSGVTVTMKDDVRTLLELAEETGLE
                     PDFSCRSGICNSCRCRLVEGKVSYLEEPLETPPDGHVLICCARPEGHVVLDI"
     gene            complement(25563..26603)
                     /locus_tag="CSC3H3_RS23240"
                     /old_locus_tag="CSC3H3_23175"
     CDS             complement(25563..26603)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013960734.1"
                     /locus_tag="CSC3H3_RS23240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23175"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_101286718.1"
                     /transl_table=11
                     /translation="MFLRNAWYVAAWSSEISRDLQQIKVLGEKICVFRTEEDEVIALED
                     ACPHRKLPLSKGRIKGNTVECGYHGLTFDCAGQCVWAPGGGRIPSAAKVRPYPTHEKYG
                     LVWIWMGNAAMADPEDIIDIPNFDSPDWGINSGDAMELQCNYLLMCDNLLDPTHVAWVH
                     ESSFAAPATKDTPLRVTKTANGVIVHRWMMDHEPAPFYRKVVEFEGNCDRLQHYEVRYP
                     AHALIRAVFTPAGTGGSDGPLHENTFVMDSYNFMTPTTENETRYYWFQLRNVRPDDDEL
                     SKMMAEDVRHAFEEDRAVLHEVQIGMSNKQSPHIDLGIDAGQLWFRRQLAAMIAEERMI
                     DARMEA"
     gene            complement(26696..27619)
                     /locus_tag="CSC3H3_RS23245"
                     /old_locus_tag="CSC3H3_23180"
     CDS             complement(26696..27619)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="CSC3H3_RS23245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23180"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_157832000.1"
                     /transl_table=11
                     /translation="MTVKSYLPPMRALQVFEALGRLGSVAGAAQELGVTPGAISQQLKI
                     LEEHLSMKLINKDGRRTALSDEALAYHRLVSEGFDRLRMAHTVLQRAKMGADLKVSGLP
                     TLLLKWLNPLLHDIQPHLGDVPLRLEATHLEPDPEMPVDMFRLTYGDVAQRFPHARKLF
                     TDICFPACSPAFLDQHPSARTAEGLLDLPLIDIDWGPAYNSVPRWADWFAAHGLAGARF
                     KTVAVHSLSSTALEAAAGGQGVVLAQRAFARFDLELGRLVRLSDDSMPMPLPYYVCWGD
                     TTLDQPKAREFLNWLIIISRKFKDET"
     gene            complement(27841..29259)
                     /gene="gndA"
                     /locus_tag="CSC3H3_RS23250"
                     /old_locus_tag="CSC3H3_23185"
     CDS             complement(27841..29259)
                     /EC_number="1.1.1.44"
                     /GO_function="GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gndA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018688578.1"
                     /locus_tag="CSC3H3_RS23250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23185"
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="WP_101286720.1"
                     /transl_table=11
                     /translation="MSEQPQVGLIGLGTMGAALSLNIAEKGHALAVYNRTASVTDAFIK
                     NAGDLAPRLTATDSLENFVAAIAAPRVIILMVPAGPVVDDHIDALKPLLGADDLIIDAG
                     NANFYDTERRAERARNEKFGFIGIGVSGGESGARHGPSIMVGGTDADWQRVAPMLEAIS
                     AKYEGTPCASLMGPGGAGHFVKMVHNGIEYADMQMIAEVYSLMRDGMGYKAPQVADVFE
                     GWNKGRLESYLIEISAKVSRADDPISGNAMLDVILDKAGQKGTGRWTAIEAQQLAVPVP
                     VIEAAVAARNLSARLEMRQRGAEHFGDAQKALEGEGIAATTLENALIAGKILCYAQGFE
                     MLAAAAAHFKWDLPMPAIARVWREGCIIRSDMLNDMATALTNNPGDNLIFAEPFSGLLK
                     ECEADLRDTVIAATRAGIAVPALAAGLSWFDTVRTRRTSANMIQAQRDYFGAHGFERVD
                     GKDEPHGPWAGHED"
     misc_feature    complement(29637..29651)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.47"
                     /tool="antismash"
     gene            29933..30331
                     /locus_tag="CSC3H3_RS23255"
                     /old_locus_tag="CSC3H3_23190"
     CDS             29933..30331
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007820588.1"
                     /locus_tag="CSC3H3_RS23255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23190"
                     /product="hypothetical protein"
                     /protein_id="WP_101286884.1"
                     /transl_table=11
                     /translation="MLIDTSQMPVILIRSKEHHDDSFETQFQQVLDRNDPFVLVSDHSP
                     EDHEDETREERKQRTLFMKKVGDQMRKLCRGMIMVTGKDDMPAAIRLVAANAGKAFGFP
                     IMFVKTEAEGIAKGRTLFDNDAGPQTSK"
     gene            30336..31316
                     /locus_tag="CSC3H3_RS23260"
                     /old_locus_tag="CSC3H3_23195"
     CDS             30336..31316
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007820590.1"
                     /locus_tag="CSC3H3_RS23260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23195"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_101286885.1"
                     /transl_table=11
                     /translation="MTQNRTTPATPLAGQKAKPDLLTAEKLAGPKSAQIDLIDRPVFSL
                     FTETTVTGEFQPHVHTKAQLMYVIDGVLTVEADGGIWTVPPKCAFWIPGGIVHKGRVVG
                     HINIGNLYLAPSLTTDMHQKCGILFVQPFLRELIMRFDNTLPTNATREANLIAVLRDEL
                     IAAPLEPIHLPMPTDRRLRRLTETMLAQPDLRFTISEWGARVGASNRTLTRLFQRETGM
                     SFTRWRQQLHIGIALQRLAAGDSVTTIAGDLGYESLSAFISMFRRMLGSSPTHYFADRQ
                     ELTQPDETSKNTGDTATPTGEDAPPSDAEISADIVILKRSPHIKS"
     gene            31517..32302
                     /locus_tag="CSC3H3_RS23265"
                     /old_locus_tag="CSC3H3_23200"
     CDS             31517..32302
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="CSC3H3_RS23265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23200"
                     /product="FCD domain-containing protein"
                     /protein_id="WP_101267023.1"
                     /transl_table=11
                     /translation="MRKPNNLKRLTPIAGTIEVRGILGAAVANLGVRIVGGEWPVGSVI
                     AKEADLVAELDVSRSVIREACRILGAKGLIRSRTSDGTRVQPRAEWRLLDPDVMDWRIQ
                     AGDREGLLRDLLKFRLVLEPGIAYSATVMANDAARQKIDAAWQAKQAVYEDTTLNEHDR
                     RAAFIDTDLAFHQAFVEAVSSELLDQVFSVISSALELLFDHQLQALGRANRLIGMDGSH
                     ELHEDVYRAFANRDAARAEEAMRVLVHRAIEDAERGFEQ"
     gene            complement(32349..33122)
                     /locus_tag="CSC3H3_RS23270"
                     /old_locus_tag="CSC3H3_23205"
     CDS             complement(32349..33122)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-125). E-value: 3.1e-14. Score:
                     45.2. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS23270_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004527760.1"
                     /locus_tag="CSC3H3_RS23270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23205"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_101286721.1"
                     /sec_met_domain="adh_short (E-value: 9.7e-37, bitscore:
                     122.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRLQGKTAIVTGGAKGIGAAIARRFAAEGGNVFIADLNLDRARE
                     TASEIAAKGGSATACQLDISDRAGVDELIAGIEARHGAIGVLVNNAGVNVFHAPLDLMD
                     EDWDRCMAVDLKGAWNCSRAVLPGMVDRRYGAIINIISNHAFSVIKSTFPYPVAKHGLL
                     GMTRALALEYADRGIAINAISPGYTDTDLAAAEFAKSPDPATARAQAEAKQPVGRLCRP
                     DEVAAIAALLASDEARFMIGENIVIDGGVTIRMYE"
     aSDomain        complement(32748..33101)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS23270_PKS_KR.1"
                     /evalue="3.10E-14"
                     /label="CSC3H3_RS23270_PKS_KR.1"
                     /locus_tag="CSC3H3_RS23270"
                     /protein_end="125"
                     /protein_start="7"
                     /score="45.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAIVTGGAKGIGAAIARRFAAEGGNVFIADLNLDRARETASEIAA
                     KGGSATACQLDISDRAGVDELIAGIEARHGAIGVLVNNAGVNVFHAPLDLMDEDWDRCM
                     AVDLKGAWNCSRAV"
     CDS_motif       complement(32961..33095)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS23270_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="CSC3H3_RS23270"
                     /protein_end="54"
                     /protein_start="9"
                     /score="18.1"
                     /tool="antismash"
                     /translation="IVTGGAKGIGAAIARRFAAEGGNVFIADLNLDRARETASEIAAKG
                     "
     misc_feature    complement(33183..33198)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.78"
                     /tool="antismash"
     gene            33219..34187
                     /locus_tag="CSC3H3_RS23275"
                     /old_locus_tag="CSC3H3_23210"
     CDS             33219..34187
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="CSC3H3_RS23275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23210"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_101286722.1"
                     /transl_table=11
                     /translation="MRSRITMLSLAAIMASVLGHSAFAADKEIVAIYKSGTQQYFIDQA
                     DGFKKAAEARGYSSNIINVELDANRAISAVSDAIASGAKGIAITAPDQAIGPAVAKAAS
                     DAKVLLVATDDPLQKNDGSAVPFVGFDGTAMGNSVGEAAVDILKKSGWMDGANYGVLAT
                     EYQTVSVCNDRTNASRQKLEDAGVAADHFKVVAYDGTTDNALQAAGPVITANPGIDKWI
                     VYACNDEGVLGATNALRNAGFNPEDVIGVGLGAYEACRPWQAGIATGFKAALYLSGADV
                     GKAAANALIDAIEGTKPLPEKTVADTTIVTPDNYKDVMPCS"
     gene            34256..35764
                     /locus_tag="CSC3H3_RS23280"
                     /old_locus_tag="CSC3H3_23215"
     CDS             34256..35764
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013223414.1"
                     /locus_tag="CSC3H3_RS23280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23215"
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_101286723.1"
                     /transl_table=11
                     /translation="MPNETVLDVREVGKSFPGVKALSNVTLQVRSGEVVSIVGENGAGK
                     STLLKILSGDYQLDEGTITLAGKEASHANPLEARDAGFRLVRQEPEIVPHVSVMENVFI
                     GEYPTRPGGRVDFAAMRQTVTALMDRYGFTGMVGIETSGRLLSPAQMHIVEILRALKDG
                     VKVVAFDEPTSSLTNNETEKLFALIATLRAEGIGIIYVSHRLHEVMEISDRVVVLKDGQ
                     TTGDLAIGETSEDEIVRLMVGRELSAHGFNRTEVTRDEVVLEVENLSSRWHQNISFSIR
                     AGEIVGFAGLVGAGRTELAKVLFGEFPRDGGTIKIGGEVKTIRSPADAIKASIGFAPEN
                     RKAEGLILVRSVLENASMAVFSSLSRLGLLRHKEMVSAVTPYIRQLEIKTPSLDHDVGK
                     LSGGNQQKVVLARWLAAKPKLLILDEPTRAVDVGAKAEIYRLIDDLAKSGMAIMMISSE
                     MPELLSMSDRIIVMHDGQISQPIEKHDATEEAIVNLALGTRNVA"
     gene            35790..36851
                     /locus_tag="CSC3H3_RS23285"
                     /old_locus_tag="CSC3H3_23220"
     CDS             35790..36851
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014684.4"
                     /locus_tag="CSC3H3_RS23285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23220"
                     /product="ABC transporter permease"
                     /protein_id="WP_157832001.1"
                     /transl_table=11
                     /translation="MNAINHSAAAPNMDRKDPLARRLLKLIGAENLSLMIALAIMVALI
                     CSQTEFFFSARNILNIGQNMAVMGLIAVGMTLVIVSAGLDISVGSIAGCASVVCALMVS
                     QAGTVLGGVAFGIGIGAILGLINATIINYLRVNPVVATLATFSAFRGVAFLIAPGGRPV
                     GALDPNLAWLGSGRILQIGSFPGLPVAFIILIIAAIAGHFIMTSTVFGRSIYSMGGNPA
                     AARLAGIKLTRMRFIIYAISGALSGLAGVIVTARTSSGQPASGTQGLELEAITAVFLGG
                     ALLAGGKGTIMGTMLAVLLLATLSNGMNLLGIPTFYQLVAKGLLLVIAVAIGQWRLARA
                     ERRQARLAATGGN"
     gene            36853..37746
                     /locus_tag="CSC3H3_RS23290"
                     /old_locus_tag="CSC3H3_23225"
     CDS             36853..37746
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS23290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_23225"
                     /product="hypothetical protein"
                     /protein_id="WP_101286725.1"
                     /transl_table=11
                     /translation="MAQATVLTLENDAVSLCCHPGFGGRISHLTDRQSGRNWLIDGTPN
                     GDEDTGPSAIYGANHARGWDECFPAIASDHTPYWGPIRDHGLLWGETHQSRITDNCLQT
                     AISLADGAITFERSLTLHGSSIIVDYNLANQGALPCPYLWSQHCLLATRPGEELVMDGL
                     GTPDPTIHAPYDDLIIRGREAQFAQKTYAALTEYHACIGIKGDAGGILFSWRRAEIPWC
                     GIWLDYGGWPNGETGQPAHHQVALEPATAPFDPLTAAQNTGYGRVLAPGQSQSWQVVIT
                     IFPAGKTLNRSSFHAD"
     misc_feature    complement(37758..37772)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.23"
                     /tool="antismash"
     gene            37763..38911
                     /gene="dgoD"
                     /locus_tag="CSC3H3_RS23295"
                     /old_locus_tag="CSC3H3_23230"
     CDS             37763..38911
                     /EC_number="4.2.1.6"
                     /GO_function="GO:0008869 - galactonate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dgoD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1268: mandelate racemase/muconate lactonizing enzyme"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018917422.1"
                     /locus_tag="CSC3H3_RS23295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23230"
                     /product="galactonate dehydratase"
                     /protein_id="WP_101286726.1"
                     /transl_table=11
                     /translation="MKITALKTFLVPPRWLFLKIETDEGICGWGEPVLEGHAETLAAKI
                     AEYADFLIGRDPGRIEDIWQSLYRNGCYRGGPVLMSALSGIDMALWDIKGKVANMPVHA
                     LLGGAVRDRVKSYCWIGGDRPTDLIGGAQKLREKGYKALKFNICSEMQIIDSYRKIDQS
                     VQMLSELRAAIGNDMDFACDFHGRVHMPMARILLREIEHLHPMFVEDAVLSTQIDEMAD
                     LSRATTIPLAIGERLHSRFDFRAVFEKRAASVINPDTAHVGGISEMVRIGHWAEAYDIA
                     LAPHCPLGPIALAACLQVDAICHNAFIQEQSLGMHYNTGGDLNDYLLPSSRYQVIDGYL
                     PIPQGPGLGIEVDEDHIIAQSTIGHRWRAPLWRHEDGSIAEW"
     misc_feature    complement(37808..37821)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.68"
                     /tool="antismash"
     gene            complement(39022..39891)
                     /locus_tag="CSC3H3_RS23300"
                     /old_locus_tag="CSC3H3_23235"
     CDS             complement(39022..39891)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonatesMeIsocitrateLyase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011568400.1"
                     /locus_tag="CSC3H3_RS23300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23235"
                     /product="isocitrate lyase/PEP mutase family protein"
                     /protein_id="WP_101286886.1"
                     /sec_met_domain="phosphonatesMeIsocitrateLyase (E-value:
                     4.5e-78, bitscore: 257.7, seeds: 9, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5e-50, bitscore:
                     165.7, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPANTLRAMLARDELITMPCCFDALSAKLIEQQGFGLTFMSGFS
                     AAAARIGAPDLGLMSYGEVLDQARNITDAVSIPVIGDGDTGYGNAMNVRRTVQGFAKAG
                     CAAVMIEDQVAPKRCGHTKGKEVVGRDEAFDRIRAAVDAREAGADILILARTDARHEHG
                     LAEAIDRAAKFAELGADILFVEAPKSVDEMRTICGALPGAKMANILEGGETPDLSPEEL
                     REIGFKIAAYPLSLMASAMKAMVETLQLLKAGQPRDNMLMSWEELRKRIGFDDYYEQSE
                     KYATSRRD"
     gene            complement(39897..41327)
                     /locus_tag="CSC3H3_RS23305"
                     /old_locus_tag="CSC3H3_23240"
     CDS             complement(39897..41327)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /locus_tag="CSC3H3_RS23305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23240"
                     /product="TRAP transporter large permease"
                     /protein_id="WP_101267011.1"
                     /transl_table=11
                     /translation="MTIVLTLIALFAVLLIRVPVAFALGGLGLAMLVLGGFSPLMAPQA
                     ILSTLDGFILLAVPLFLLMSNVLLQAGVGKDLFAAVSAWVGHWPGGLAVATILSCGVFA
                     AISGSSVATAATIGTVAIPEMINRGYNKRFVYGLLAAGGTLGILIPPSIPLIIYGFVTE
                     ESVISLFLAGIGPGIALLVLFIVFSMIYARLGGQVPEPKKNWNERWAATFKAFPAILLA
                     VLIIAGIYGGAFTPTEAAAIGFAAALAITIPVLRLPASMILADAVYYMVFKGQGPIIGY
                     FLLPIIVFGLFRGFDRLVTRMNIRVVMPALGWDGIKKAAFESMATTVSVILIIAGAKVF
                     GKAITLYRIPQDISVLISHNVDTQLGFVLVVSVVLLLMGLVFEALSMVLIMTPVLLPAA
                     MALGIDPIWFGVYMVIMVECALITPPVGMNLYVIQSVARTPLGEVSKGVFPFILLMFLT
                     AVILYVWPDLALYIPFKL"
     gene            complement(41324..41812)
                     /locus_tag="CSC3H3_RS23310"
                     /old_locus_tag="CSC3H3_23245"
     CDS             complement(41324..41812)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007092236.1"
                     /locus_tag="CSC3H3_RS23310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23245"
                     /product="TRAP transporter small permease"
                     /protein_id="WP_101286887.1"
                     /transl_table=11
                     /translation="MYNRFIVALAWIGALLFVAAGLMLSWEVVARYFFVRPTIWAAELS
                     QLCLIWGSLIGMPWALATRRHIAVDAITRLCSPTMQRVLEILAMAVVGIFSIVVAWKGF
                     GIFFESLERGRTTGSMLDLPTWISELPVFVGFALLAIQSLIEIIRVVMGREIPQGAHE"
     gene            complement(41964..42953)
                     /gene="dctP"
                     /locus_tag="CSC3H3_RS23315"
                     /old_locus_tag="CSC3H3_23250"
     CDS             complement(41964..42953)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="dctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007092237.1"
                     /locus_tag="CSC3H3_RS23315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_23250"
                     /product="TRAP transporter substrate-binding protein DctP"
                     /protein_id="WP_101267007.1"
                     /transl_table=11
                     /translation="MKKIAMIAALMAAVGVSGAAQAADVTLRIASQLPPKSHIVQNLEL
                     FKKEVEEKSNGNIAVEIYDSATLYKDKEIPSAVGSGSIEMGSASLTRYAGDVPAVDVFY
                     QPFVLDSEAKVRAAVAPGSPVRGPLDKAIADTGSTVLWWQAYGGTIMLSKGAPIHTPKD
                     LEGKKVRVFGKSLGEFTEAAGGAPTLISGSEQYLAYQRGTVDIGMTGISGVKSRKLWEV
                     MDTVTITNMADVEFLVMINTDFWNGLTDDQRAIITEASRDAEKDVRDRMSAIEAAAFKE
                     SEEAGMTIYTPTDEEVKQWRAVSQPVYDSFLNSAGDLGKQVFDAAKKL"
     misc_feature    42971..42984
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
ORIGIN
        1 ccagacggcc actttcaatc tgccgcttgg cattacctac tatcagctta tgctacgcat
       61 ccgtgcggac cttggcagcg gcattgttga cgtgccggtt gccagcttgg gcgacgtgat
      121 cggcgaaatt cgcatgtata tcgacggaca ggaaaccatc cgcgttgacg ccgctgattt
      181 ggccgtgatc cttgcctata aaggccagac ggttaaggcc ggtgccttgc cgctgatgtt
      241 tgccaatccg tcacagcgca cggcggcggg cgaggatgct ccggccattg gcactcaatt
      301 tcttcaatcg ctttcgcttg aaattgacat caaggacggt gtgacgtctc ccagtctggt
      361 ggtctatggc cgcatggggc caaatacgcc gctgggtcag ttttacgcaa tcaagaaata
      421 tccgtttaac gtgggcaacc ttggcacgcg ccagttacag gaattgccgc gtacgtccta
      481 caacctgctg gcaatgcata tcagcacgga tcagatttcg agcgtccagc ttgaagcaaa
      541 tcagcgcatt atccgcgatt ttgaccgggt ggtaggcgag gcaaccgcca tccagaccgg
      601 caaggtctgg cagccgggct ttacccacat cgacatggtg gaaagtgatc ggctttccga
      661 catgctgccg atgcttttgg aatctttcct gctgcgtttg gaaatggagg caacgggtaa
      721 cttcaatctg tacaccgaag aagtgcgcgg tactgtcgct gcctaatcgg aatgggccgg
      781 ggtgcaatgc actccggctt gccttggggg gatcacatgg cagaacaaga caatcagacc
      841 agtccggggg gctgggaagg cgcattagac aacctgttta aatattttgg acaggcaaaa
      901 gatgcggtct tttcgaccta ttccgattgg caaaatacct ttggtggcga gaacagcgcc
      961 agcaattcca gtaactacgc cagtggtgaa aactatgaca gtggttggtc aaatccggct
     1021 gcgccagtgc aaaccagtaa tcccaatctt gggctttaca tcggcgttgg cgtggcactg
     1081 ctggcgggta tgattttaat cacccgaaaa tagggggcga acatgtttca gggacttatg
     1141 agcatgttcg gcggcggcgt gggtggcggt tctggcggtt cgtttatcga cacgaccagc
     1201 catgccacgg cgggcagcac atcggaaagc gggcatattt attcctacaa taatgcgccg
     1261 ttttccgttg gtggggccgc acaaacgccg gtcaatatga ttgcatccat cgtgccttgg
     1321 gttgttatgg ggggagtggc atggctgctg ctgaaaaaat aaaaatcggc ctgtcacagt
     1381 gggatcaaac ggcggcggag catatccgcc ccgttgtcct gcccgaaagc ccgcttggcc
     1441 ttgatggtct gcgcgatgat gttgccaacg gtcgcgccgc tgttcttgcc gtccaggcac
     1501 gcggcgaacg cattggcacc ctgcttgtgc gggtcgaaca gggtggagac ggcaaatatt
     1561 ttatcatcga atgcgcgaac agccatttgg ccggggttga tctggtcaaa acctgtatgc
     1621 cggcccttga agcatgggcg cgcaagctgg gctgccgggc cttggacgtg ccaacgcacc
     1681 gccccggctt ggtgcataag atgaaaaaac aggattacac cgttgttaaa acggtattgc
     1741 gaaaggttct gacatgagtg cgggcctaag tcattcaagc agcaaaagca gcacgaccag
     1801 ccagaactat gaccagcggg ccggggctga caacgggtcg attgccgcca gtggcggcgc
     1861 aacggtcaca attgacgcaa ccagcccgga agccttcgat tttgccggag acgtggccgc
     1921 cgatgtgatc gacctgacca gcgttgttgt gggtggcacc ttcggggcgc tttccgatgc
     1981 aaataagacc gtcggcgcgg ccttggaagc ggtccgcaaa gcaaacacgt ccgacactgc
     2041 aaatacgctg gaactgttga ttaaaatcgg tgtgccagtg cttggcgcgg ctttcatcct
     2101 gcccgcgatc tttaagaaat aggtttagac atgaccatta gccgttatca gacttataca
     2161 ggcacgatcc agccgggcga actgtttacc attaaccggg cagggcggtc agttacctgt
     2221 tttgaagcca gcgcgggcct tgaaatcgtc attgatgacg gctcaagttc agcgttcttc
     2281 gccggggtca gtgtcgattt tgattacgag ttcaaacgca ttcagttgct gaacccgaac
     2341 gatacgccgg tgacgtttca agtcgccacg gccatgggaa aggtgaacga taaccgcctg
     2401 acagcatccg gcattttgcg cgttgctgat cctgatagtg gtgcaagttt tagcgctgtg
     2461 cgtgccgccg ctgtcgatgt agcgaacgca gttggtgaat taagtaaacg cgctaatgaa
     2521 gctatgcagg gcagcaatat gtttatgttg tatgccccca agcacaaaat cggcacgtcc
     2581 tttatgtacg ttcagggtgt tggatcgtct cctgttacct taattgatcc ggctgtaaat
     2641 acgtctggcg tcattatcag aacagtcgtt gcaaacaacg gcgcggggaa cggagccagc
     2701 atttttgcag ggccgtccgc gcctgcaagc tgggtggacg caacaaagcg gcaaatctac
     2761 agtttttatt caagttatac gcagtgctac aaccactgcg atcctattca tctgcccgct
     2821 ggcgatgggc tgtatttcct cggtaatcaa ggtggatcag ccagcttgag tgttacatgg
     2881 gattacctgt aatgaccaat tttgaaatca tgcagttggc ttatcagttg cgcgggcagg
     2941 gcgatgaccg cccgcttgcc gatattgttg ccagcgtcaa agctgacatg gccgtattcg
     3001 agccagccgc acccggtccc ggcgatgtgg tcgggggccg tgttgatcag ttccccgacg
     3061 gtcgcaaggt cacaaccgaa atcttgggcg atgggactga aaaggtcatc aaaaccgaaa
     3121 tgatcgacct gccaaaaccc gaaccggagg ccgcacccaa tgaataagga tgcacttttg
     3181 ctgatcggtg ccggtggtct ggcctatgcg gctttcatgg ctgcccgatc gggcgcaacc
     3241 gaacagtctg aatatgacgt aggaagcccg tcacgggtgg cgcaagatgt tgacgtgctg
     3301 gcccggacaa tctggggtga ggcacgtggc gaaggtgcca gcggtatgca ggctgtcgcc
     3361 aacgtcgtga tgaaccgtgt ggctaaacag acgtggtacg gcaaaacagt cgtagaggtc
     3421 tgcaaaaagc ccggccaatt taccgcctgg acaaaaggcg atccgaacta tgagccagcc
     3481 catgccgtaa ccaccaataa cccggccttt gcgcaggcct tgcagattgc aggccgtgcg
     3541 gttgctggca cgttgcccga tatcaccggg ggcgcggatc attattttaa tcccagtgtg
     3601 gttttaccaa gttgggcggc cacaatgagc caccttatcg acattggtcg ccatgccttt
     3661 tatcgggcgt aagggggaat aatggcggtt cgttacgatc cagacctgca cgcggttgaa
     3721 tatgcggcgg gcaaatggat ggcctgcaac gcactggatc aaaccgcctg catcaacatg
     3781 gcggaagaag tcgcagctta tgaaaatgat ccaacggcaa cgccggggcc gttcgatggt
     3841 aacgacgcgc cgctcgtggt gaatatcgaa aagactgtga tcaattggcc gttaatcggc
     3901 ctgttcttgg ccgggctgct tatggccgtg gctggtttga aaagggggta atcgtgcgtt
     3961 tggggttgcg gttacagcac atcaataagg gggaaaatga catggcgaaa cgcaagggcc
     4021 gcaaggctaa cgggcagttt gccaagggca acaaaatcgg caagcgccga acacgccgca
     4081 aaggccgcaa gtaatgccgg tgctgcttat cggggttgct atcggcgctg tcatcggagg
     4141 gtcgggggtc tggcttgcca gtgacgccgc ccaaaaggtc ggtaatgcgg ccctgatcgg
     4201 tggcggcatc tatctggctg gcaaatacat gaaaaaatgg tgagccatgg atttgccaat
     4261 tgccgaaatc ttgcaggggg gcggaaatct cgcatctatc gcccttgtgc tgatcatgtg
     4321 gcggtttgat cgccgcttgt tgaaactcga aattcagctt tcaggggagc attaagaatg
     4381 tgggaaaaag tgaaagaccg tttcaaggaa ccgtccacct atgccggttt ggccggtgtg
     4441 attacgtctg tcggtgtgct tggcaagatc aacgaagcgc cagccattgc cgataccgtg
     4501 agcaacgcgg gccatgcaat cagccagggc gattatgcaa ccgccatcgg cgtcggcctg
     4561 tttggtctgc tgtcgatctt catcggtgag aaaggcaaac gttaagggaa catcttaacg
     4621 ggatttgcga aggaggcgtg tttgttcacg cttccttttt ttgtttcagg tgtccggggc
     4681 gcaagatcgg gcgcaatatt cgcgatacgc taacctcatg taatccggtc ctttttgcga
     4741 tctggcggtt gttaaagccg cgtgcagcca atttcgtaac catcaaatga cgggcgcgaa
     4801 ctgttgccgc gtcgttcgct ttcaggaaca tcttgtaata gtgcgcaacg gtttcaggcg
     4861 ggcaggaatg gcgatttgat aaaatttttt caacctgctt ttgctcgtac tggttgagca
     4921 tttcagacat ttcatatccg attgctttta ggctattcaa ccgggcgctg atatttatca
     4981 gattgctttc acgctcggcg atttcctcgg ccttggcgcg cgccttgcgg gcgaagtcct
     5041 cataggcatc tgcaagtttt attagggcat ctttatcaag atggtcgaga agttttctat
     5101 ccattgtgtc atgcgagttt aacagggcct taaagggttt aacaggcatg gttaacatat
     5161 ggttaatctc taagtgattg aaaatgtggg gaaaatggag aacaaacaag cataattagg
     5221 ttctataata aagattatga caaataatta gcaggatgga tttgcaatat agaccgcaat
     5281 ctcccgcaca tcgctgaatg ctacttacat tctgctttta acaagcacaa tgtcaggacg
     5341 cgggtctcgc tgatttcgta gctaacctgt agataatggg taagggattg caaatcctcg
     5401 gctgtgaaga cgaaagaaag cagattgcgt tccaacgcca cgcatcgggc ctctttgaaa
     5461 tctataaagc gatctacaac cgggaacaat gccttataga ccgcctcttt cgcggaaaac
     5521 agtacggtac aggcaacgcg ctggctgaac ctggacaaaa gcaggatctg ttctgtatcg
     5581 gtcgcgattt gcgaaaaaag gcgccgcgca ttgtcctggc aaatcatctt ctccatatca
     5641 ataccgatcc cacgataatc actttgtttg gcaactatgg cacaggcaat atctgcatcg
     5701 tgactaatcg ccccaacaat gccttgcggc cagatcggct cccggtactg acccattggt
     5761 acagaaattt cattacatcc aaggtcacaa agtgcccttg cacaacacaa tctcccagcc
     5821 agaaattcgt tcttacgttt tgggacggct cgagccaatt gtgcgggcag ttcaatctgc
     5881 aaaccatctg gcccaactgc agtcagatcg gtctcgggga tttgcggaat tagacatgcg
     5941 tgcccacaaa gcccgttcac ctggtatagc gccggcaaag gttggccaag atcgccattc
     6001 atttatttcc cctgatatcc tggaattcca tcgtatcgga ttatacacca ccctgccctt
     6061 tattatttca ttcaaaaatc atctaaatac acatttcagg aaattaaaaa tcaatacatt
     6121 tttccatcac accaaaaatg tttcgagatc ataagcgggc ctgaaacagc atgcctgcaa
     6181 caacagttta atcacctcca aatttttacc gaagaccccc acctttgaat aggcatcact
     6241 gaaaatttgt aacattcaat gcatatttcc agaggaaacc gaccatttct tactcaaaaa
     6301 acaccgttta atattctgaa agtctgaata gttagggata attatatttc cagcggcatt
     6361 aattcttatc ataagctgat ttttcggatg gatttagcaa ggaaaccgct gtgtcttata
     6421 atcgaaggtc aaaaacgata accgaaggaa tagagcggtc gccgaaccgc gcaatgtttt
     6481 atgccctggg ttatcaggaa gaagatttcg acaagccaat gatcggggtt gccaacggcc
     6541 agtcgacgat cacgccctgc aatgccgggc ttcaaccgct tgcagatgca gccattgcgg
     6601 ctattcgttc cgccggtgcc aatccgcaaa ctttcggtgt gccaacgatt tcagatggta
     6661 tgtcgatggg taccgaaggc atgaaatatt cgctggtttc gcgcgaggta atcgccgatt
     6721 gcatcgagac gaccgttcag ggccaatgga tggatggcgt gctcgtcatt ggcgggtgtg
     6781 acaagaacaa gcccggcgga atgatcggca ttattcgggc aaatatcccg gccatttacg
     6841 tgtatggcgg tacaatcaaa cccggtaact ggaagggcga agacctctcg attacgtctg
     6901 ccttcgaagc tgttggcgcc tttcgtgccg ggcatataag tgaagaggat ttcaaaggca
     6961 tcgagaaaaa tgcctgccca acgacaggct cctgcggcgg aatgtacacc gccaacacaa
     7021 tgagctcgtc ctttgaagca ctgggcatgt cattgcttgg ttcatcaaca atggccaatc
     7081 ccgacgccga aaaaaccgtt tcagcagcag attccgcccg cgtacttgtt gaagccgtta
     7141 agaaaaatat acggccaagc gatatcatca cccgcgaaag tgttgagaac gctatttcgc
     7201 tggtcatggc gacgggcggc tcgaccaatg ccgttctgca ctatcttgcg atctgcgatg
     7261 ccgcaaatat tgaatggacg ctggatgatt ttgaacgggt caggcgcaag gttcctgtct
     7321 tttgcgacct gaagccatcg ggcaaacaca tggccgtcga cctgcaccgt caggggggcg
     7381 tgccgcaggt actcaaacag ttgctcaatg cgggactgct gaattccgaa tgccttacca
     7441 ttaccggtcg caccatcggc gaagaacttg caaatgttcc cgatgcgccg ccgagcggac
     7501 aggacgtgat ccggaccatt gccgatcccc tttacgcaga aggacatctt gccgtcttgc
     7561 gcggaaacct tgcacaagac ggggcagtgg caaaaattac cggtttaaaa tcgacggcaa
     7621 taacgggccc cgcgcgcgtt ttcaatgacg agcaatcagc attaaaggcc attttgtccg
     7681 gcgagataac agctggcgac gttcttgtat tgcgttatct cggccccaaa ggtggcccgg
     7741 gaatgccaga aatgctcgca ccaacgtcgg caatcgtcgg acagggatta agcgacaagg
     7801 tcggcctgat aactgacgga cgattttccg gcgggtcctg gggcttactc gttggtcacg
     7861 tgacccctga ggcatacgaa ggcggtacaa ttgccctggt cgaggaaggc gatatgatta
     7921 ccattgatgc caatgcgggc cttctggcgc ttaacgtcga tcaggacgag atcgaacgcc
     7981 ggcgcaaaaa ctggcaccag cccgccccgc gttatacacg cggtgtactt tcgaaattcg
     8041 cacgccttgc acgcccggcc agcaaaggtg ccggcaccgg ttaatacccc catgtcagcc
     8101 tgctcgcttc cgattgaaac cttgcgtaat cattgtgaaa tccagaacga aaacaatgtc
     8161 cttgtccatg ccctatgatc aggcgagcat acttaccgcc cttgcaacct atattgttgg
     8221 tgccgccagc ccggggctgg gcaatatggc aattgcatcc acatccgttc aaagtggtcg
     8281 catatccggc tttgccgtca tgttcggtgt tctggctgcc gggcagacat gggcattgtg
     8341 cgcggccgct ggattgtcat caatcctgct gacaatgcct tccgcgatgc atctgatcgg
     8401 catcgttggt ggcatgtacc tcgtatggct ggcattcaaa acgtttaaaa acaaacgcac
     8461 aaaaaaccgg atggaattcg ccccacatgc aggcaaatcg tctacggccc atcattttcg
     8521 caaaggattt tttatccaga tcctgaaccc gaaagccgtt ctgggctgga tacttatcat
     8581 ctcgatcggt gttcggcccg aatctccagc ctacacaccg atcatcatcg tgttgtgctg
     8641 tcttatcctg ggcatgatca ttttttccag ctatgtcatg cttttctcac tgatcggcac
     8701 caggcccctg cccttgggca gcatgtccct ttttcgctat gccgaaccca tcgtctattt
     8761 ccttgccgga tcatggctgg tggtcgacag cctgaaatga tgaaaatgga aaaagccgct
     8821 gctgccgatg acaacaatca ttacgctaaa tttaaaacct ctttctccgg aattgccaaa
     8881 ggttttgcga gattgatcaa acgtttaaca gcgggcgatg aatcctcacg ccgccagaca
     8941 aggcccgttt cgataaacgg tggcgcacct tcaagcggga cataacacgt cccggtacga
     9001 tccagattgc gcaatgcctc aggcacaagc gcaatcccca gcccgctgga aaccaggctg
     9061 atgattgtct gcatctggat tgcctcctgc ccgatctcga gcttgtagcc ggattgcgag
     9121 aaatatcggg tgattatgtc gtaaaatgcc ggggcaatcc tgcgcggaaa gatgatcagc
     9181 ggatgttgcg caatctcggc taaccggatc tttccgttaa cacaggtgat gcgtccgttc
     9241 tctatccagg cttttggtac cgtcgcaacc agcggctctc gcagcatggg cagatattcc
     9301 agcgaatgat caaacatttg atgtgcggga atgatcatac cgacatcaat ttccctgttc
     9361 aggatggctt cggcctgcaa atcactggtc atttcctcaa gatcaagctt cacatccgga
     9421 cagttcagcc tgaaatcagc aaccagcctg ggcaaaagac tgtaagccgc cgtcgaaaca
     9481 aaaccgaact tcaaaacgcc aatttcacca tgcgcaatct gcttggccaa aagcggcagt
     9541 tgttcggcat tgtcgagaac cttccgcaca cattccagcc aatgttcgcc aacggccgtc
     9601 agctcaacat gtctcttggt gcgattgaaa agggtaacgc ccaattcctg ttccagggcg
     9661 ataatcgcct gactgaaagg cggttgcgtc atattcatgc gttcggcagc acgactgaaa
     9721 tgcagttctt cagccaacgt aacgaaataa cgaagttgcc tcaggttcaa cgccaacctc
     9781 cgccactaaa cacagaccat ccagcttctc agaggcagca acgatagcgc atccaaaatt
     9841 ggttgtctat ttccaaacaa ctctaccata gggtgtgacc gccaaatacg cggtgtctgt
     9901 ggcatcggaa gtggcgtttt tcgctacgaa aaacgcgcct ccctctcaat acggaccagg
     9961 ctcaaagaca aaacttatcg cgagaaaaaa gcagtctgag acgtaaatca ccaaccggat
    10021 catcacgcaa aaatttctcc tcaaagacta aaaacaggcg ctcgaaaggt tctgtattat
    10081 ccgcgaatat tttcacctca acgatcccgt catatttaat aattcagtgc ccttgcctat
    10141 tccgctccgc aatataatat tgtgcatttg cgaacaaaaa aatcggccaa aaataaaaaa
    10201 cgaccccgcg gtaaataata tattttacaa atcaatcaat acgtaaatag aatttttcgc
    10261 aaacttgttt tttaactaaa atgaagtcaa caaactttca aatgcgtgaa tgaaaaacct
    10321 cattctgaaa aaccataaca ttcatttaaa cgcatatttt aaataaggga ggagtttacc
    10381 tgatgattaa tcagatggac gatgttgcct gccaactatt ctcggaaaac aatcccacgg
    10441 atggacccag aaaaaaggtc atcgatagtc cgtatctcaa taaattccaa agaattcatt
    10501 tcattctgtt tgatgttgca cctgcaatcg gcgcagtagc tactgtcgtg gtctctctaa
    10561 catacaaagt cacgtcatta gacctggtcc tctttgcggt catgtggctg ttctccggac
    10621 tggggatttc ggttggctat caccgcttgt tcacgcaccg taccttccag gcttccccaa
    10681 ctgttcgcgc cttacttggt atttttggct caatggccgg tcagggaggt gtcatctcct
    10741 ggacggcaat gcatcgccgt caccatgaat gcggtgacca ggaaggggat ctccattccc
    10801 caaacctttc cggtccaggt tggaaaggct ggattaaagg gttcgtacac gcccatttca
    10861 catggatgta tgcccactcc taccccaatg tctcccatta tgcgcccgat ttgctgaaag
    10921 atcgtgtgat tgtttgggta aatcgccggt attacacctg gatcgtcttg ggcttactta
    10981 ttccaacggt cattggtggg ttatattcgc aaacatggat gggggcgcta accggttttc
    11041 tgtggggtgg cgcaatgcga atgttcgtgg tcgaacaggg tattttttcc ttgaattcgc
    11101 tatgccatct gatcggaaaa cgccgtttta aaacgcatga ccagagcaca aatattgcgt
    11161 ggctgtcccc gttcatcttc ggggaatcct ggcaccacaa tcatcacgca tttcccggtt
    11221 ctgcctcttt tggcctggcg tggtaccgca ttgatcccgg ctattggttc atatgcttgc
    11281 tatctgttct gggtcaggca tgggacatca aaatacccac gcgcgagcaa attcaacgac
    11341 gagaacttcc caaagcacaa gcatctaccc gaccttaaag gagagcctga caatgaaccg
    11401 tattctgcct gagaaaaaca ttgatgaagc ggcaatcttc cagtggcttc agacatatat
    11461 atgcaagacc ctggatatga atcccgcatc cgtaggactt cacgacaatc ttgattctct
    11521 cggaatggac tcagctatca ccacggcact ggcgatggat ctggaaggtt ggctcaatat
    11581 cgaaatccct ctttcaatcc tgttcgaggc cgacagccta gaacaaattg cggcaggtgt
    11641 ttcggcagaa atcaatcgtc agcaggtgag cgtagaatga atcagtcagc attgaaagaa
    11701 gtgcccgcat atggcggctc cccaagcgcc attcagtttc attacgatgt cggccgcgaa
    11761 ttttatcaat tgtggcttga tgactctatg acctattcga gtgccttatg gagcgagtca
    11821 gatgacgaca cccttaatgc cgcgcaacag cgcaaaatcg actatcatct cgaacaggcg
    11881 cgcgccagac aggccagttc gttgctcgat atcggctgtg gttggggggc actggttaac
    11941 aaagcaagct cccttcccaa tcttcataag atcgtgggtc tgacacttag taacgaccag
    12001 gccgactatg ttcgcggctt tggcttgcca aatctcgata tccgcttgga aagctggacc
    12061 gaacaccacc caacgacaca ttatgatagc atcatttcag tcggcgcgtt tgagcatttt
    12121 gtcaagcccg aagacagcac ggcagaaaaa attgccacat atcgcgattt cttcgaaaaa
    12181 tgtgccggat ggctttcgcc aggcggctgg ctttctcttc aaactttcgt ttacggaaca
    12241 atgaagaatg aagaagccag cgcattcatc aaccatgaaa tctttccggc agcggacctg
    12301 cctcgcctgg aacaaatcat ggcatcggtt gatggcgtta tggaactcac caaattggtg
    12361 aatcacagac tgcattatgc gcgaacatat gacatgtggg cgcgcaacct acgacggcgg
    12421 cgtgacgaag ccgtcgatct cgttggcgaa gccatgacca acaaatacga acgttatctc
    12481 aagcaaacgt caatcggatt ttacaccggt aaaatcggtc tgttgcgtat gacgttccgc
    12541 cctgtggacc gctccctttc cgtacttgcg aaagagtaac cacagcaacg caagcctttc
    12601 atttcatgtt gttctaacaa cgggtggcaa ccgccggcct tccgatcccc ggcggctgtc
    12661 ctcctgtgtc aggtgaaccg taaggaacat tcgatatgtt agcctcttca gaaactgcaa
    12721 cggttcttcg aagaccaaac ctggtcttta atccccttga cccggaattc aggaaaaacc
    12781 cctacccgct ttatacacga ttgcggcgcg aagcacctgt attgcgcagc aagggcatgc
    12841 tgattttatc acgctacacg gatgtccttg ccgtcttgaa aagccgtaaa ttcagtgttg
    12901 gcctgatccc ggaaaccgtc accacccaag catccaggat cggctttcag gacatcgcgc
    12961 aaatgcgccg cttcctcgat acgtccatcg tctttaccga caatccggaa catatgcgtc
    13021 tccgccggct ggtcaatcag gctttttcca aagaagccat atatgcgttc gttccaatga
    13081 tagagcagcg gatcgagaag ctgcttgata tacatagcag aaaaggtcac tgcgagatca
    13141 tcgaagacat cgctgttccg ttgccaatcg acatcctatg cgactggatg ctcatcgaag
    13201 aagaagcccg gcctcaattc tccaagaaag tccacgccgt aaggcagcta ctggatccag
    13261 ggatgatgag cagatccgac ttccaggccg cagccaaagg catgcgcgat ctgaccgggt
    13321 ttctggccga tcatgcttcg cgggtcggca aaatcgatga cggcaacctg gtctccagac
    13381 tatgtaacgc ccgcttcgag gaacaaggcc tcagcgatga ggaaatcgct tttacctgcg
    13441 tgatggcctt cgtcgccggc acggaaacaa cccagtcttt gattggcaat atcgtctata
    13501 cgcttttgca caaccctgac cagttttcgt caatcttgaa ccgtgaaggc ggggtttccg
    13561 ccgccattga ggaaatcaca agatacgaaa ccccgttgca gtttaccaaa cgccaagcgc
    13621 tggaagactg caaggtcgga gacatcgaat ttctcaaggg ggaacaggtt ctgctttgtc
    13681 tgggggccgc gaacagagac gaaaccgttt ttgaagatgc cgcacaacta cgactggaca
    13741 gatccgggcc aaaacatgtg gggttcgggt ttggcatgca ttcatgcctt ggcgcacttc
    13801 tggctgccct gcaaagcgag attttcctgc aggtacttct gtctgaatat acgggcttcc
    13861 gtcaaatcag caaaaccgtt gactggcaaa acagcagtct tatcttgcgc ggcccatcga
    13921 cgcttgagat cgaattctcg cgtaaacagg tgatacagtg agccggttcg cagaaatatt
    13981 tgggaacgct cgtcccgata cgtgcgtcga cctttatgca tttcaccatg cagggggcag
    14041 tcgtcattcc tttgctgcct ggcagaaccg gtttccgcgc gctatcaacg tatatcgcgc
    14101 tcaattgccg ggcagaacac ctgaaagcta ccatttctta cctcgcaagg tagcagagtt
    14161 aattccagat cttgcagcgt gtttccttcg gagccgtttt ggcaacatca acccctttgt
    14221 gttctacggt catagcctag gggcgctcgt cgcattcgag cttacgcgct ttttgcgtca
    14281 acatagcaaa acgctcccaa tcggtctgat cgtatcaagc cgccgcgccc cgcaatgtcc
    14341 tttggtctat tcagaattat gcagcctgcg cgatgatctt ctgcttccca aattggagga
    14401 acttggcggc gtccctgcct atctgaaggc gaaaccggat gaactccggc gtcttttacc
    14461 tgtggtcaga gctgacctgc tgctgtcgga ccgctacgac tacaatgaac aaccaccgtt
    14521 cgatttgccg gtcctagcca ccaagggcct gcatgatcca attatgtctc tagccgagct
    14581 caaagcttgg tctgaccaga ccaccggcaa attcgaatgt ttggaactat ccggtgccca
    14641 tttcttcgac agccatggca gcacccgtct ggagaaactc cttacggaaa cagtaatacg
    14701 ttgggggaat gccccctcgc cgacgcctag aaaagccatt ctaccactgg aggaaacaca
    14761 atgctgaact cggtcgatgt cagaacaacc gaaacccgaa ctgttcccac catgtggaat
    14821 ctcctggaaa catatgtcgc gaccaaagcg gatgagagag ctttcatttt tctgggcccg
    14881 gacaatgtcg aacaggaagt cctcacttat ggcgccctcc atcgacttgc cgttgcttac
    14941 ggaaaacagc tacgactagc gacccagccc ggtgatcgtg cgattctgat gtttccaacg
    15001 ggactgtcgt tcatcgtctc gtttctggca tgccattttg ccggagtggt tcccgtaccc
    15061 atggtcccgc tgaagggcca gcgtttacgc gatacagtat tggcaattgc cgagaattgt
    15121 gcggcaacgg tcgtcatgac cacgtcggaa caatcggaat tcctgaaatc acaattgtca
    15181 gtactgccga catatgcaga tgcaggattt attggggtca atgttgacct ggaatgcccc
    15241 ccagtcacca gtaacgacac acctcatcca gcccaactca gcgaactggc tttcatccaa
    15301 tatacctctg gatcgacctc tgtccccaag ggggtgatgg tttcacatgc caacctggct
    15361 gccaatctcg agatgatgac catcgcctac gaaaacgatc aatattcaag ctatgtcggc
    15421 tgggcacccc tctatcatga catgggtctt atcgcgaatg ttctggaacc attctatctg
    15481 ggtactctat gcgtcctgat ggcacctaac ctgtttgcgc accgtccatg gctttggctg
    15541 aaagcgatta gcgattatca ggcccatgta agcggcggcc cgaattacgc atatgatctg
    15601 tgtatcgaac gggccgagga aattctcgaa atggggtttg acctgtcttc ctggcgggtc
    15661 gccttcaata gtgccgaacc cgtccgagcc gagacattac gccggtttac cgccgcattc
    15721 atgccactag ggttccggcc acagaccttt tatccatgtt tcgggatggc cgaggccact
    15781 ttgctcatca ccggcggcac acgtgcccag gtgcccctaa tcgaaaatct gagtcgaacc
    15841 ggtctggcaa acggaatggc gatcgaagcg aacgacccca aagatacaat agaggtggtt
    15901 ggttgcgggc aggttctgca gcaagaagac atccggatcg tcgatcccca ttcaaccatt
    15961 gaaaaacccg acggtgaaat cggcgaaatc tgggttgccg gaccacacat cccttttgga
    16021 tactggaaca accctgtcag ttcgaaggaa acctatcagg caacgattgc aggaagtatt
    16081 ggacccagat ttctgcgaac cggcgatctt gggttcatgc aagcaggtga attatatgtc
    16141 accggacgtc ataaggatct gatcattgtg cgcggacaca atgttttccc ccaagatctg
    16201 gagtttatcg ccgagcgtgc ggcaccggga ctaaaacgca attccggtgc tgcctttgcc
    16261 atcgaagatc cttcagatgg gcaacaaacg ctttgtcttg tgcaggaagt catgctgagc
    16321 cagcgatata ccattgatgt tgatgacact atcaaagcca ttcgtcaggc gattatgaaa
    16381 gaaaccgaca tcacggttca caagatcatt cttgttcagc caagttccat tcccaaaaca
    16441 tcaagcggca agatccgacg ggcggaaacc aaaaagcgtt atatcgacgg tacgcttctg
    16501 gttgttcagg cgcaatcctc ggccgcaaca cgtcaaaagg caacggcctg aaggaacagg
    16561 aaaatgttgg taaccgcaga acacgaaaca gcgcccaaac ccgcatattc gcgcgaagaa
    16621 atcgaggcca tcatagcaaa aacgcccttt gccgcctggg ccggcgcaaa gctggtctct
    16681 tataaatatg gagaagttga aatcaacctt tcgatgaggc gggagctaac tcagcatcac
    16741 ggctttggcc atggcgcaat tgttggatta ctggcggata gcgcctgtgc ctgggcagcg
    16801 gcttccatcg tcggcgatgt cgttacagcc gaatacaaac tgaatttcct ggcacctgcc
    16861 gtcggtcaca cgcttcttgc atatggatcg gtccttgggc cggccgggcg ccaaaccgtc
    16921 tgtcgagccg atatttactg ccaaactcaa tcgagaaaaa ttctcgttgc aacggcgctt
    16981 gcaacgatcg cgcaggtagg ccgcgcataa taacgaaaca ggaggatgtc cgatgtatca
    17041 caaagaatct ttcctttcct ctgacatgcc ggtaatcgtc tggtccccca acgaaggtca
    17101 atcacttggt gtcgacgacc tcagcgatta tctggcatca caaaaagaac ttattctgtc
    17161 ccgaatacag gaaaagggcg gaattttgct gcgtggcttt gaatgtatcc ggacgtcaga
    17221 tgactatcag aaaattctcg atgcggttgc tcccgacctg atggaatata tcggtggtac
    17281 atcaccgcga aaagtcgtca atggtcgcat catgacggca accgagattc cgggttccta
    17341 ctccatcccg cttcatcaag aaatgtccta tacagacaat tcgcccgatc tcatatcttt
    17401 cttctgcgaa atccccccgg aaaacggagg tgagaccaca atcggcgaca tgcgtacgat
    17461 tacccgtgaa atcagcgatg atgttcgcgc ccgtttcctt gcccataacg ggatccagct
    17521 ttgccggaac ctcccaacac cagaacgcgt cgagatgcgg cccggtgttc caaaatcatg
    17581 gccagaggcc atggggacac acatcaggga agaagccgaa aatgtcgccg ttaaatcggg
    17641 ctggcgttac gagtggctgg aagacggatc catgcagctc tggcaggaaa tccgcccggc
    17701 tacccggaaa caccccctca ccggagaaga agtctggttc aaccagattc agatattttc
    17761 ccccgttctt tccctaaagt gggcacgtga agacggtcgt gatgacgcgg ccgaccgcct
    17821 ctccaaagca cttgccgaag caccgcatct actcgatcac atgcgttatg gtgacggcct
    17881 gcaaattgat gaagaagacg ccctgcatat ctacgacaca ctttccgcaa atgcagtgcc
    17941 actacaatgg caaaggggcg atgtcctatt cctcgacaac atcctggtag cccatggacg
    18001 acggaaattc agcggacaac gccgcattct gactgccctt atccaacatg cccattgagc
    18061 ggacgcagct tgccctgacg gagagaaacc atgttgaaca cgtcaatcaa gaaattcgga
    18121 agtcaccatt cggtgaagca gccggggggt tcagttgaga ccgaagtgtc actgcgtatc
    18181 caacttgctg aattctacca tctggtcgcc tatctcggct ggaccgaagc gatcttcaat
    18241 catatctccc tgcggcttcc tggcacggat agccattatc tcgtgaaccc ttttggtctg
    18301 cattacgagg aagtgacacc ggaaaatttg gtgactgtcg atctcgccgg taatctggtc
    18361 ggcccgtccc aatatcctgc aaaccctgcg ggctttgcgc tccatggcgc aattcacgag
    18421 gttcggcatg atatgcattg catcgcacat acccacacga ccgctgtttc cgctatcgcg
    18481 ctgaaacagg atgggttcca gcatgatgac ttttatggtg cacaactttt tgaacaggtg
    18541 gcctatcacg atttcgaggg cgtaacactt tttgccgatg aaaaaccgcg cattctcaaa
    18601 agcctggggg acaaaaacgt actggtcatg agaaatcatg gcatcgctgt cggtggaaga
    18661 gatgttccca gaactttctg gacccttttt acagcacaac gtgccgcgga aatccagtgt
    18721 caggccggta tgctgccagg caggaactca attttatcgg atcaggtaag acagcgctgt
    18781 tcgaaagttg ccgacgacct agcggcaaat gcgtcctttg cacaaaaaat gttcgacgga
    18841 atggtcagga aaatgcgccg ccataccggc cctttgtggc caggggacaa cggcattgac
    18901 cggcttcact aaaccggtcg gaacgacttc cacgtgggac gaacacataa taggggatat
    18961 cggcaaatgt tagagcttca ggatagagac agacagtgtg aacccgatgt cggactatgg
    19021 accggttgcg tcgagattgc actcggaatg ccgcaccttg ccttaaaggg tctatcggag
    19081 gcctgggtcc ttaaggaact gggacatctg cattggacac tgcttgcgcg gatggcaaaa
    19141 cgtaagtttc ccgattttca ggatgctgcc ggaaatgttg tctatgcggc ttttcgctcc
    19201 gtcgaagttg aaggtgcccg ctttggcctg gcatgcgaaa atgacatttt gcggatcact
    19261 tcaacccaat gccgaatttc ccgaacccaa atccaaagtc gtcacacctt aaccatcaac
    19321 aatgaggatg acgacgcagg tattgtcatc ggtgtcgtca cgatggtttc tgttttcgtg
    19381 caccgaacca accacacatc aaaccgttcc attgcgcgcg ttgagataca gggcctcccc
    19441 ccgattacag ggcatcaact tgcgccccgg cacaagtggt ttgacgacaa caatctgttt
    19501 accgcgacag agggaaacaa tcgccaggta cagagcttcc ttccctgccc gtcgcaagac
    19561 ttcaacggag caggtttttt atatttcgca aatttttccg cattcgttga ccgggccgaa
    19621 ctgaacctgg acccaacatt ttcccgccaa gccgtcacca gtcaacgaca cataaaatat
    19681 cactccaatg tcgatccggg agaacccata cgtgttgaaa tcatggacct tgagcgttca
    19741 tcgtcaaact ggctccatca atgcaggata tcgcgcgaaa aagacggggc acttatggct
    19801 gatattatta cagaaaaatg tattcccgaa gccataggtc cgaggcgttt ttcgccttca
    19861 ccacaaaata ctgcctgata tcgcgggttt catcgagtac cggttgctaa tgttttcaca
    19921 ggcccgagaa acgaagaaag tacctagcac cccacaaacc ctgcattttg ccctgttttg
    19981 ccaagaagat gatgacaaca atgatgtcag aagtaatgac ccgttcggtg ttggaaagta
    20041 tccacgaaac cgcaattgca caggaccatc tgatcgcaat tgaggatggt gatcgaaaac
    20101 tgacatatgg gcagctctgg acatgcatgt gtttacttgg acggcaagga ctgacaacac
    20161 ctcatccggg tctgatagca atatgcggac gaccatctat cgaaaccgct cttggcatcc
    20221 tggccgcatt tctgtccggc gatgtggcag ttccgatcga tgacagactt ccgttatccc
    20281 gccgcgagga attggcccag tggtgtgata tatcatacga caaggaagag attgtccgga
    20341 tcacatgtga tgtggctgct tcaccgagta tgacctgccc ccctttaagc aagataaaaa
    20401 gagaaaagcg ccgcccggcc tatgtggcat tcacctcagg caccaccggt gtcccaaagg
    20461 caatagaagg cacaatgacc gggctggatc atttcattgc ttggcagtcc cgactaattg
    20521 gccaatgggt tcaaaatccg cgagtatcat ggctcacgcc attatctttt gacgttatgt
    20581 atcgtgacct tcttctgccc ctcaacaata gaggaactct tgttattccg gacagccagc
    20641 aggatttcaa cattgcggcg gcgtggaact ggctgaatga ccaaaaaatc gacatcgcac
    20701 atgttgtccc ctctattgtc ggcacttggt tgaacgggcg ccactccggg cccctgtcgg
    20761 tcaaggctct attttttgcg ggagagccct tacgccaggc actgatttcc cgcctgaagg
    20821 aaaattacgt taatcggatc tacaatcttt acggtccgtc cgagagtaca atggcaaaat
    20881 tctgccgctt gattgatgac aaatgcacac caacggattc actatatcca gttggaatgc
    20941 caatcgatca tgatgtttct tacgtcctat ccaaggatca ggaaatcatt atccggtccg
    21001 cgtatctaac gaatggctac cgacaaaagg acggcacagt tgcgcccttt ccctccactt
    21061 cggaaaactg ccccgaatat cacaccggtg accggggtcg tgtcattgat ggggaactct
    21121 atgtattggg acggctcgac agccaactca agattaatgg cattcgcata gaagcatcag
    21181 aaattgaatc gttagccgaa cgctatcccg ggataaggcg aaccgccgct gtgaaacttg
    21241 cccccccgga ttctactgtc gaaattatcg ttctgttcta tcagggggac cttgagcgga
    21301 aagacaagat gcgcaagctg ctcgcagaac atctccatcc ggcggtagtt cctaccgctt
    21361 acctgccaat tgcggatttc ccactgaccc tgaacggaaa aatcgatcgg caaaaattga
    21421 aggaacgtgc tgcaacagaa catttgatgg acgatccatc gtctataaaa ggcacaggaa
    21481 ctgaagaatg cgacaatttc gagcaacgtg ttcaagaaat aatgtcgagc atcttgcggt
    21541 atccatgcag gctcgacact gatttccttg atatcggcgg taattcgttg atgtttggcc
    21601 tgatcacact tgaactacat tcaactttcg ggctcaccat gccccaacag gagttttata
    21661 actctggcac accgcgtagc gttgcagcat ggttacgaca gaacggtgca agcgtaaagg
    21721 tttcagcatc cgcaccatca gagccaactc ctacgtctaa ccgcagcgca acaggaccgt
    21781 ggccgttaac gccccgtcag caaacaatcc acgatatatt ccataatgag ttattcggtt
    21841 cgggcatgaa tatgatcttg caagtcccgg tcgccgccga tcaaatggaa cgagttaaag
    21901 cagtcgtatc gcaaatcgtt gcccaaaatg actgtttcca tcttaatttc cggtatcggc
    21961 atggcaaact gtatcagtat ctgtcgccac ctgactttag aatcaatgat atcgatgtaa
    22021 tagaggctcc atgcgtagac catgacaggt tatcagccga gttcgcgaca cggccgtttg
    22081 atctggctga agagaaacca tttcgcgtcc gcctgcttaa agattctgct ggcacgggac
    22141 gactgctgtt tctgatgtat catctcatta gcgacggtat gtcgcaggaa tatctcaggc
    22201 gggacatcct ggatgggatt tcaggcaacc cgatacctct gcgcaatcat tattcaccga
    22261 gtttacagtc cgaacaacgt gcactttccg acaggatttt gcctttctgg aaggaacatc
    22321 tggatggtgc aatgcccaca gccagattca taagtcccca gcacatcaca aacgtctcgg
    22381 cacgatgcat gaccgttgcg ctggcgtctg attacgaccg tctcatggga cacttaagaa
    22441 cgttaaattc aagcatattc ccctaccttc tgtcccactt ttaccgcgca ctggcaaaac
    22501 atgccgcaaa agcagacctg attatacgtg taacaacgca cggtcgtgac aaaccagaac
    22561 ttgctgatgt catgggctgt attttcagtg ccgttcccgt tcgtcttaac tgcgcaggct
    22621 ggcccacaaa acaaatcgtc gattatatta acaatcacct cgatactgca cggatgtatc
    22681 aggatctctg ctttcagaaa ctggcccaag cccttggtga aaaacaggat atccatcttc
    22741 atccactaac tggtataagc ttcacccttg acggtttcga cattactgaa aacatgcctg
    22801 ccagccagtc gaaatcccca caaatcgaaa ccatgaatgc caagctaccg cacgaattac
    22861 gcgctattgc acgaccttat cgtaatggct gcattctaaa attcgtctat cgcgccaaag
    22921 cattcaccga cgaagatatt ctagccatat catccgccat gcagggggcg atcgccggcg
    22981 aactccagcg atgactagac gaaaaatcac aaacatctcg tcatcccttt gggggcgata
    23041 tcaagtagtg atgccctaaa ccatttacga tgaggtctta atcagaaaaa tctatgaagt
    23101 taacgcgcag aaacttcatc acaacaccgg tttctttagc ttaaatgcta agcagaaaca
    23161 aataccgccg cgtaaattca gcctgacaac cccgtctaaa atggggggac tacctctgca
    23221 cccgcgctaa ttaacaaaca ctcatgatca cccatttaat tattcacaga tcaagtgtca
    23281 ctggggaacg gaaaacgggg cagaggctgc ataatcaaga aacccgcatc acaggagaaa
    23341 cgttcgtgat ccttcaatta tttccggtat gggcattatt gctctcgtta ctggcatttt
    23401 tcatgccagg accattcgca tctcttagca ccggcattgt accattattg actgtcatca
    23461 tgctggccat gggtcttaca ttaacagcaa aggatttcgc caatgttgcc aaaagccgca
    23521 aggcactggt ggttggcgtg attttgcagt tcctgatcat gcccgtcgcc gcctggctgg
    23581 tggcaaagct gtttggcttt gatgacgacc ttaccgttgg tatgcttctg gtcggcagtg
    23641 tggccggtgg cacatcatca aatgtgatgt gttatctggc aaagggtgat actgcccttt
    23701 ccatttccat gacagcgact tccaccctta tcggtgtatt tcttaccccg gttctggtcg
    23761 cctttttggc cgggcaaagc attgatgtgc cggttcaacc catgctgatg tcgctggtca
    23821 aaattgtttt ggtgcctgtt atcattgggg ttgtccttaa cgaaatcgcg tcaaaatggg
    23881 ttcgcaaaat cgaagggatt tttccctata tttcgatgtt cgccatcctt ctgatcatcg
    23941 ccattgttgt cgccctgaat gccgacaagg ttgccagtgt tggcctggtc gttgcctttg
    24001 ccgtgatcct gcataacgca attggcctgt cgctgggtta tggcgtaacc gctcttctgg
    24061 gttttgatcg caaaatctgc cgtaccattg cctttgaagt cggcctgcaa aattccggcc
    24121 ttgcgaccgc attggcgatg aagtttttca ccccggtttc ggccttgccc ggcaccttgt
    24181 ttagtgtctg gcacaatatt tccggctcgc ttctggcggg gtattggagc cgcaaaccgg
    24241 ttgatgagag cttagacgaa cccgtccgca aagacgcgcc cgcataatta acccgacatg
    24301 atcaaaccgg acccaaggtt acaaatacct ttggtccggt gattgaaccc tgcgaaacag
    24361 gccaccattg acgatcaaat catcaaatat caagcacaac atggccttca ggccgcgcac
    24421 aacaaatcag cacatgacca tctggcggcg tttccaatgg ttcttcaaga taagagactt
    24481 tgccttcaac caggcgacag cgacagctat tgcagatgcc cgaacgacag gaaaaatccg
    24541 gctccaaccc tgtttcttcc gccaattcca ataacgtccg tacgtcgtct ttcatggtca
    24601 ctgtcacgcc agatttcgca aaccggacga tattcccgct gttccccgcc ataccggacc
    24661 ctgcattcgc caacggttcg gaagcatccg ggatggccca tgcctccggg tccgtcagat
    24721 gcaccagtgc ggcaatcgcc tttggggcac gcgacgcggc tctgggcacc tgtattggct
    24781 gctctgccag tttctctagc gatgaggcgg cgccaaagaa ctcatacgca atgcggtttt
    24841 tttcgatgcc aagcgaacgc agcaggcgat acatggcgat cataaaagcc gtcggaccgc
    24901 acatataaac gtcataatca tcaaacggca gaagcgactg caacagcgcc ttatcgatca
    24961 aaccctcact atcgaacccg cgctctgcgc ggtcacgcgc cgttggctgc cgatatgcca
    25021 catgcaaaca tatccgcccg tcagaggccg cagcaagcgc cttaagttcc ccgccaaacg
    25081 cctgaacatc cccattttcg caggcatgga caatccagac ctgacgattg ctgcgtgcca
    25141 gcacctttgc cattgccagc aagggcgtta ttccgatacc accggccaga agcaccacgg
    25201 ggcgtatact tgcctgatcg aggacaaaac cgccgcgcgg tggggcgata tcgatttcat
    25261 gcccctcctc tacccggtca tgcagccagc acgacccaac tccatcggga aaatcactgc
    25321 catccggtgc gccttcccgc ttgaccgaaa tccgatgaaa attatcctgc tgcacatcgc
    25381 cggaaagcga ataggttttc aatactgttc ctgcaccatt tggcacccgc agggtcagat
    25441 actgcgcggg taatgcctgc caaagcggcc cgccatcaac cggcataaag tggaaagagg
    25501 tcacaacatc gctttcgcgt atcctggccg taacgcgaaa tttccgaaac gcatccgtca
    25561 tgtcacgctt ccatcctggc atcaatcatt cgctcttcgg cgatcatcgc ggcaagctgg
    25621 cggcgaaacc ataattgtcc cgcatcgatg cccagatcaa tatggggcga ctgtttgttg
    25681 ctcatcccga tctggacctc gtgcagaaca gcacggtctt cttcaaaggc atgccgcaca
    25741 tcttccgcca tcatctttga cagctcatca tcatcaggcc ggacattgcg aagctgaaac
    25801 cagtaatagc gtgtttcatt ctcggtggtt ggcgtcatga aattatagct gtccatgaca
    25861 aaggtatttt catgcagcgg cccgtccgaa ccaccagttc ccgccggggt aaaaaccgca
    25921 cggatcagcg catgcgcagg atagcgcacc tcgtaatgct gcaaacggtc gcaattgcct
    25981 tcaaattcaa cgaccttcct gtaaaacggt gcaggttcgt gatccatcat ccagcgatgg
    26041 acaatcacac cattcgcagt tttggtaacg cgaagcggcg tgtctttggt tgcgggggcg
    26101 gcaaatgaac tttcatgcac ccaggcgaca tgggtggggt caagcagatt atcgcacatc
    26161 aaaaggtagt tgcattgcag ctccatcgca tcaccagaat taatgcccca atccgggctg
    26221 tcaaaattcg gaatgtcgat gatatcttcc gggtctgcca ttgcggcatt acccatccag
    26281 atccagacca ggccgtattt ttcatgcgtt ggatagggcc gaactttggc cgccgatggg
    26341 atacgaccac cacccggcgc ccagacacat tgcccggcac agtcaaaagt cagcccgtga
    26401 tacccgcatt caacagtgtt gcctttgatc cgccccttgg atagcggcag cttgcggtgc
    26461 gggcatgcat cttccagtgc aataacctcg tcttcctcgg ttcggaaaac acaaatcttc
    26521 tcgcccagaa ctttgatctg ttgaagatcc cggctgattt cgctgctcca tgcagcaaca
    26581 taccatgcat tgcgtaaaaa cattgacgac ctcgcgggta acttggggtt acccgcacta
    26641 tgtctgaaca tggtatattt aacaggcaga aatgctcgga aacagtttag atattctacg
    26701 tttcatcctt gaatttccgg ctgattatga tcagccagtt cagaaattct cgtgcttttg
    26761 gctgatccag ggtggtatcc ccccagcata cataataggg caatggcatc ggcatgctgt
    26821 catctgacag ccgcacaaga cggccaagtt ccagatcaaa ccgcgcaaag gcacgttgcg
    26881 ccagaacaac accctgcccg ccagccgccg cttcaagcgc agtgctggaa agcgaatgga
    26941 ctgccaccgt cttgaacctg gcccccgcca agccatgcgc ggcaaaccag tccgcccagc
    27001 gtggcaccga gttataggcc gggccccagt caatatcgat cagaggaaga tcaagcaggc
    27061 cttcagccgt acgtgccgat gggtgttggt ccagaaaagc aggcgaacag gccggaaagc
    27121 aaatatcggt aaacaacttt cgggcatggg gaaaccgttg cgcaacatcg ccataggtca
    27181 ggcggaacat atcgaccggc atttccgggt ctggctcaag atgcgtcgct tcaagccgca
    27241 aaggcacatc acccagatgg ggttgaatat cgtgtaaaag cgggttcaac catttcaaca
    27301 aaagggttgg caggcccgaa accttgagat cggcccccat tttcgcacgt tgaagcaccg
    27361 tatgggccat acgcaaccgg tcaaacccct cgctcaccag ccggtggtag gccaatgcct
    27421 cgtcagaaag cgctgttcgc cgcccgtcct tgttgatcag cttcatcgac agatgttctt
    27481 caaggatctt gagctgctgg ctgatcgcac ctggtgtcac gccaagttcc tgtgcggcac
    27541 ctgcaaccga tccaagccgc cccaaggctt caaacacctg caaagcccgc atcgggggca
    27601 aataggattt caccgtcact tacctgattt ccagccgaag catgctaact gcgcgacaca
    27661 gtaaaacagg aatgctgaat tgtccccgtt ttatgtggcg taaaaattac gacaaataat
    27721 tttaagcgta ccctgcatct gacatgtcat cccatccatt gatagcggcc ccaaacgtcc
    27781 aaaaaacaaa aacggcggcg cattcacata cgccgccgct ttcaaaagcc aatgataaaa
    27841 tcagtcttcg tggccagccc aggggccgtg cggttcgtct ttaccatcca cacgttcaaa
    27901 gccatgcgca ccgaaataat cgcgctgcgc ctggatcata ttggcggacg tacgacgggt
    27961 acgcaccgta tcaaaccagg aaagaccggc ggcaagtgcc ggaacggcga taccggcacg
    28021 ggtcgccgca atcacggtat cacgcaaatc ggcttcgcat tctttcagca ggcccgaaaa
    28081 cggttcggcg aaaatcaggt tatcacccgg attattcgtt agcgccgttg ccatgtcatt
    28141 aagcatgtcg gaacgaatga tgcagccttc acgccagacg cgcgcgatgg ccggcatcgg
    28201 caaatcccat ttaaaatgcg ccgcagcagc cgccagcatt tcaaaaccct gcgcataaca
    28261 caggattttc ccggcaatca gcgcattttc aagcgtggtg gcagcaatac cttcgccttc
    28321 cagggctttt tgcgcatcgc caaaatgttc ggcaccacgc tggcgcattt caaggcgtgc
    28381 cgaaaggtta cgcgcagcaa ctgcagcctc aatcacgggg acgggcacag caagctgctg
    28441 ggcttcaatt gcggtccagc ggccggttcc tttttggcct gccttgtcca ggatcacatc
    28501 aagcatcgca ttgcccgaaa tcgggtcatc cgcgcgcgaa accttggccg aaatctcgat
    28561 cagataggat tcaagacggc ctttattcca gccttcaaac acatcggcaa cctgcggcgc
    28621 cttatagccc atgccatcgc gcatcaggct gtaaacctca gcgatcattt gcatatcggc
    28681 atattcaata ccgttatgaa ccatcttcac aaaatggcct gcaccaccag ggcccatcag
    28741 ggatgcacag ggtgtgcctt catatttggc agaaatggct tcaagcatcg gtgcaacgcg
    28801 ctgccagtcg gcatcggtgc cgcccaccat aatggacgga ccatgacggg caccgctttc
    28861 accacccgaa acaccaatac cgatgaaacc gaacttttca tttcgtgcac gttctgcacg
    28921 ccgttccgtg tcatagaaat tggcattgcc ggcatcaatg atcaggtcat cagcacccaa
    28981 aagcggctta agggcatcga tatggtcatc aacaacgggg ccagccggca ccatcagaat
    29041 aatcacgcgc ggtgctgcaa tcgcagcaac gaaattttcc aggctgtccg ttgcggtcag
    29101 gcgcggggcc aggtcaccgg catttttgat aaacgcatcg gtcacacttg cggtccggtt
    29161 ataaacggcg agtgcatggc ccttttccgc aatattcagc gacaaggccg cgcccatcgt
    29221 tcccaaacca atcaaaccca cctgaggctg ttccgacatg ttcactttcc tatttctgat
    29281 cttgtgggac gaagaagaac agcacatcac gctgcccgtc ttttaaagtt tatcgatcaa
    29341 gataaaacga aatcacaatc aggggcaaat atccgccctg cccttgatgg gcaacacaca
    29401 ggcccgtatg cggccatcag tgtattgcgg ggcattttga tgtgatgtcg acctgcatca
    29461 gtgtttgtac cccatcccct aaaccccttt gcggtttgcc gtccggtttt gcggatcgcc
    29521 gcgcaaatat gcgcgcaagc aaaaggattc cgggatttgt tcacaaacaa taacaaggtg
    29581 atatctcaat tttcgtgctt aacatagcgt ggtgataatc atttcgcacc tgtttgcgaa
    29641 aatgattttt acattcactt gcgaaaattc cggttgcttg tggccccaaa gcccgcatca
    29701 cagcacaaaa atcgcccatt tatggcgcta tgttccgggc atcaaacccg ccatttccgc
    29761 cctgccaaat tccagtttgg cgcaaccgcg ccagtatttg accatccggc aacagccagg
    29821 gccaagcctg gctgatatat caatcatcag tcaaacaccg cacatcccct gcccgcctcg
    29881 tgtgcgcgca tcgacaagtt gccaccaaac gagcgaatta ctggaaatac ccatgctgat
    29941 cgacacatcg caaatgcccg ttatccttat tcgtagcaaa gaacatcacg acgacagttt
    30001 tgaaacccag tttcaacagg tgctggaccg aaacgatccg ttcgtgctgg tttccgacca
    30061 ttcccccgaa gaccatgaag acgaaaccag ggaagaacgc aaacaacgca cccttttcat
    30121 gaaaaaagtc ggcgatcaaa tgcgtaaact ttgccgtggc atgatcatgg tgacgggcaa
    30181 ggacgatatg cccgcagcca ttcgcctggt agcagccaat gcgggcaagg catttggctt
    30241 tcccatcatg tttgtaaaaa ccgaggcaga aggcatcgcc aaaggccgca ccttgtttga
    30301 taatgatgcc gggccccaaa ccagcaagta aagccatgac gcaaaaccgc acaacccccg
    30361 caacacccct ggcaggccag aaggcaaagc cggatttgtt aacagccgaa aagctggccg
    30421 gacccaaaag cgcacaaatt gacctgatcg atcgtcccgt cttcagcctg tttaccgaaa
    30481 caaccgtcac gggcgaattt cagccccatg ttcataccaa agcccagctt atgtatgtga
    30541 ttgacggcgt cctgacggtc gaggccgatg gcggcatctg gacggtcccg cccaaatgcg
    30601 ccttctggat tcccggtggt attgttcata aagggcgggt tgttgggcat atcaatattg
    30661 gcaacctgta ccttgcccca tccctgacaa cggatatgca ccagaaatgc ggcatccttt
    30721 ttgtgcagcc gtttttacgt gaactgatca tgcggtttga taacaccctg cccaccaatg
    30781 ccacccgcga agcaaacctg attgccgttt tacgcgacga actgattgcc gcaccgctgg
    30841 aacccattca cctgcccatg cccaccgacc ggcgcctgcg ccgtctgacc gaaaccatgc
    30901 tggcccagcc cgatttacgc tttaccatca gcgaatgggg cgcacgcgtg ggtgccagca
    30961 accgcaccct gacccgactg ttccagcgtg aaaccggcat gtcctttacc cgatggcgtc
    31021 agcagcttca tattggcatt gccctgcaac gccttgccgc aggcgatagc gtaaccacca
    31081 tcgccgggga tcttggctat gaaagcctga gcgcgtttat ctccatgttt cggcgcatgc
    31141 tgggtagcag cccgacacac tatttcgccg accgccagga actgacccag ccagacgaaa
    31201 ccagcaaaaa taccggcgat accgcaacac caacaggtga agatgcaccc ccgtctgatg
    31261 cggaaatatc agccgacatt gtcattctaa aacgcagccc gcatataaaa agctagcgcc
    31321 agaccagcct tgtcattatt gcaggcaaag cgcgtgtatt tccggccatg gtgacaaagc
    31381 ccggccatgc cacaaggcag aaggccattg gggcattagg gcatttggcc tcgcccataa
    31441 aatccacggt ttgatcatag tgacaaagcc agcgtttctt tataagatga tcatataaag
    31501 aaacaggaag gccaatatgc gcaaacccaa taatctcaaa cgtctgacac ctattgccgg
    31561 aaccatcgag gttcgcggta ttcttggcgc ggctgttgcc aatctggggg tacgaattgt
    31621 tgggggggaa tggcctgtcg ggtctgtcat cgccaaagaa gccgaccttg tcgccgaact
    31681 cgatgtcagc cggtcggtca ttcgcgaggc ctgccgcatt ttgggggcaa agggccttat
    31741 ccggtcgcgc acatcagatg gcacacgcgt acaaccccgc gcagaatggc gtctgctgga
    31801 ccccgatgtt atggactggc gcattcaggc cggggatcgc gaaggtttgc tgcgcgatct
    31861 tttgaaattc cgcctggttc tggaacccgg cattgcctat agcgccacag tcatggccaa
    31921 cgatgccgcc cgccaaaaaa tcgatgccgc atggcaggcc aaacaggccg tatacgaaga
    31981 caccacctta aacgagcatg accggcgcgc agccttcatt gataccgacc ttgcctttca
    32041 tcaggccttt gtcgaggctg tcagctccga attgctggat caggtttttt ccgtcatcag
    32101 ttcggcactg gaactgctgt ttgatcatca attacaggca cttggccgcg ccaaccgcct
    32161 gattggcatg gatggcagcc acgaactgca cgaagatgtc tatcgcgcct ttgccaaccg
    32221 cgacgccgcc cgcgccgagg aagccatgcg cgttctggtc catcgcgcga ttgaggatgc
    32281 cgaacgcggg tttgaacaat aaacccgccg ggccacgcaa aggccatgcc cctgaccttg
    32341 acgccggatc attcatacat ccggatcgta acacccccat caatcacgat attttcgcca
    32401 atcataaaac gtgcctcatc cgatgccaga agggcggcaa tggcagcgac ttcatcgggg
    32461 cggcacaggc gaccaacagg ttgtttggcc tcggcctggg cgcgggcggt ggccgggtca
    32521 ggcgatttgg caaattcggc agcagccagg tccgtatcgg tatagcccgg cgaaatggca
    32581 ttaatggcaa tgccgcgatc cgcatattcc agcgccaggg cgcgtgtcat acccagcaaa
    32641 ccatgttttg ccaccgggta gggaaaggtt gatttaatga ccgaaaaggc atgattggag
    32701 atgatgttga taatcgcgcc ataacgccgg tccaccatgc ccggcaacac tgcgcggctg
    32761 caattccaag cccccttcaa atcaaccgcc atgcagcggt cccagtcttc atccatcaaa
    32821 tccagcgggg cgtgaaacac gtttacccct gcattattaa ccagcacacc aatcgccccg
    32881 tggcgggcct caatcccggc gatcagctca tccaccccgg cccgatccga aatatcaagc
    32941 tggcaggcgg tggcactgcc gcccttggcg gcaatttcgc tcgctgtttc ccgggcgcgg
    33001 tccaggttca gatcagcaat aaaaacattg cccccctcag cggcaaaacg gcgtgcaatt
    33061 gccgccccaa tcccctttgc cccacccgtt acgatggccg ttttcccttg taatcgttgc
    33121 attttttaac acgctttctc tcggctgttg actttataag attaacatat aatctttgaa
    33181 atgtgaacaa aacataaaat acctaccggg aggattaaat gcgttccagg atcacaatgc
    33241 tatcactggc tgccatcatg gcatccgtgc tgggccattc ggcctttgcc gccgacaagg
    33301 aaattgtcgc gatttataaa agcgggaccc agcaatattt catcgaccag gcggacggct
    33361 ttaaaaaagc agccgaggca cggggctatt catccaacat catcaatgtc gaacttgatg
    33421 ccaaccgcgc catcagcgcg gtatcggatg ccattgcttc gggcgcaaag ggcattgcca
    33481 ttaccgcccc cgatcaggcc attggcccgg ctgttgccaa ggcagcgtcc gatgccaagg
    33541 ttctgctggt tgcaactgac gacccgcttc agaaaaatga cggatcggcc gtaccatttg
    33601 tcggctttga tggcacggca atgggcaatt cggttggcga agccgccgtt gatattttga
    33661 aaaagtcggg ttggatggat ggtgccaatt acggcgtact ggcaaccgaa tatcaaaccg
    33721 tttccgtctg taatgatcgc accaatgcat cacgccaaaa actggaagac gcaggtgttg
    33781 ccgccgacca tttcaaggtc gttgcctatg acggcaccac cgataatgcc ctgcaggctg
    33841 caggcccggt cattaccgcc aatcccggca tcgacaaatg gattgtttat gcctgcaatg
    33901 acgaaggtgt gctgggcgca accaacgccc tgcgtaatgc cgggttcaac cccgaagacg
    33961 tcattggtgt tggccttggt gcctatgaag cctgccgtcc gtggcaggcg ggtattgcaa
    34021 ccggctttaa ggccgccctt tatcttagcg gggccgatgt tggcaaggcg gcagccaatg
    34081 ccctgattga tgccatcgaa ggcaccaaac ccctgcccga aaaaaccgtt gccgatacca
    34141 ccattgtcac cccggacaat tacaaggatg tgatgccctg tagctgatca ccctgcccgg
    34201 atgccgtcgc aacaaccgta tcggtggcat ccggttccat atccgggagt ttgaaatgcc
    34261 aaatgaaact gttcttgatg tccgcgaggt tggaaaatcc tttcccggcg tcaaggccct
    34321 gtccaatgtg acattgcagg tcagaagcgg cgaagtcgtt tcaattgttg gtgaaaatgg
    34381 tgcaggtaaa tcaaccctgc ttaaaatcct gagcggcgat taccagcttg atgaaggcac
    34441 aatcaccctt gcaggcaaag aagccagcca tgccaacccg ttagaggcac gtgatgccgg
    34501 ttttcgtctg gtccgtcagg aacccgaaat cgtgccccat gtcagtgtga tggaaaatgt
    34561 ctttatcggc gaatatccca cacgccccgg tggccgggtg gattttgcgg ccatgcgcca
    34621 aaccgtaacc gcccttatgg accgctacgg ttttaccggc atggtcggaa tcgagacgtc
    34681 agggcgtctg ctatcgcccg cgcagatgca tatcgtcgaa attctgcgtg cgcttaagga
    34741 tggcgtcaaa gtcgttgcct ttgacgaacc cacatcgtcc cttaccaata acgaaaccga
    34801 aaagctgttc gccctgattg cgaccctgcg ggcggaaggc attggcatta tttacgtttc
    34861 acaccgcctg cacgaagtca tggaaatttc cgaccgggtt gttgttttga aagacggcca
    34921 gacaaccggt gaccttgcca ttggtgaaac cagcgaagat gaaatcgtcc gcctgatggt
    34981 aggacgtgag ctttccgccc atggctttaa ccgcaccgaa gtcacccgcg acgaggtcgt
    35041 gctggaagtt gaaaatctgt caagccggtg gcaccagaat atcagctttt ccattcgtgc
    35101 cggtgaaatt gttggttttg caggccttgt gggggccggg cgcaccgaac tggcaaaggt
    35161 gctgtttggt gaatttcccc gtgatggcgg caccattaaa attggtggcg aggtcaaaac
    35221 aattcgcagt cccgccgatg cgatcaaggc cagtatcggt ttcgccccgg aaaaccgcaa
    35281 ggccgaaggg cttatccttg tgcgctcggt tctggaaaac gcctcgatgg cggttttctc
    35341 gtccctctcg cgcctggggt tgttgcgcca caaggaaatg gtttccgccg ttacccccta
    35401 tatccgccag cttgaaatca aaacacccag tcttgaccac gatgttggca aactttcggg
    35461 tggcaaccag caaaaggttg ttctggcgcg ctggcttgcg gcaaagccca aacttctgat
    35521 ccttgatgaa ccgacccgtg cggttgatgt gggcgccaag gccgagattt atcgcctgat
    35581 tgatgacctc gcaaaatcgg gcatggcgat catgatgatt tcatctgaaa tgcccgaact
    35641 gctttcgatg tccgatcgca tcattgtcat gcatgacggc cagatctccc aaccgattga
    35701 aaaacacgac gccaccgaag aagccattgt caatcttgcg cttggtacgc gcaacgtggc
    35761 ctaggcccgg tggaaaaagg aactgtgtga tgaatgctat caaccattcg gccgctgccc
    35821 cgaatatgga ccgaaaagac cctttggcgc gccgtcttct taaactgatc ggtgctgaaa
    35881 acctgtcttt aatgatcgcg cttgccatca tggttgcgct gatttgcagc cagaccgaat
    35941 ttttcttttc tgcccgcaat atcctgaata tcgggcagaa catggccgtc atgggcctga
    36001 ttgccgttgg catgaccctg gttatcgttt cggccgggct tgatatttcg gtggggtcaa
    36061 ttgccggctg tgcatcggtt gtctgtgcac tgatggtcag ccaggcgggt accgttttgg
    36121 gcggtgtcgc ctttggcatt ggcattggtg ccattctcgg cctgataaat gccaccatta
    36181 tcaactatct gcgcgttaac cccgttgtgg caacactggc aacattttcc gcctttcgcg
    36241 gtgttgcctt cctgatcgcc cccggtggcc gcccggtagg cgcgcttgat cccaatcttg
    36301 cttggcttgg ctccggtcgt attctgcaaa tcggcagttt tcccggttta ccggttgctt
    36361 ttattatcct gatcattgct gcgatcgctg gccatttcat catgacgtca acggtttttg
    36421 gccgctcgat ttattcgatg gggggtaatc cggctgcggc ccggcttgcc ggcatcaaac
    36481 tgacgcgcat gcgctttatc atctatgcca tttccggggc gctttccggg ctggccgggg
    36541 tgatcgttac cgcgcgcacc agttccggcc agcccgcatc gggcacacag gggctggagc
    36601 ttgaggccat caccgccgtc tttttaggtg gtgcccttct ggcagggggc aaaggcacca
    36661 tcatgggcac catgctggcg gttctattgc ttgcaaccct gtcaaacggc atgaatttgc
    36721 tgggtattcc cacattttac caattggtcg ccaagggttt attgctggtc attgcggtgg
    36781 ccatcggtca atggcgcctt gcacgtgccg aacgccgcca ggcccgcctt gccgccactg
    36841 gtggcaatta acatggcaca ggccacggtc ctaacccttg aaaatgatgc tgtttcactt
    36901 tgttgccacc ccggttttgg cgggcgcatt tcgcacctga ccgaccggca aagcgggcgc
    36961 aattggctga ttgacggcac accaaacggg gacgaggata caggtccatc cgccatttat
    37021 ggcgcaaatc atgcgcgtgg gtgggacgaa tgttttcccg ccattgccag tgaccacacc
    37081 ccctattggg ggcctatccg cgatcatggt ctgctgtggg gcgaaacgca ccaatcccgg
    37141 atcactgata attgcctgca aacggcgatc tcacttgcag atggggccat aacatttgaa
    37201 cggagcctga cgcttcacgg gtcatcgatt atcgttgatt acaaccttgc caatcagggc
    37261 gccctgccct gcccgtatct gtggagccag cattgcctgc tggcaacccg ccccggcgag
    37321 gaactggtaa tggatggtct gggcacacca gaccccacca ttcatgcccc ctatgatgat
    37381 ttgatcattc ggggccgcga agcacaattt gcccaaaaaa cctatgctgc gctcacagaa
    37441 tatcatgcct gcattggcat taagggcgat gcaggcggca tccttttttc ctggcgccgg
    37501 gcggaaatac cctggtgtgg catctggctg gattacgggg gatggcccaa cggcgaaacc
    37561 ggccagccag cgcaccatca ggttgcgctg gaaccggcaa cagccccctt tgacccgcta
    37621 accgccgccc aaaacaccgg ttacggccgc gttctcgccc ccggtcaatc gcaaagctgg
    37681 caagtcgtca tcacgatatt tcccgcagga aaaacactta accgatcatc gtttcacgct
    37741 gattaagccc aagagaataa acatgaaaat caccgcactg aaaacatttc tggtgccgcc
    37801 aaggtggctg tttttaaaaa tcgaaacaga cgaaggcatt tgtggctggg gcgagcccgt
    37861 tttagaaggg catgccgaaa cccttgccgc aaaaattgcc gaatatgccg atttcctgat
    37921 tggccgcgac cccggccgga tcgaggatat ctggcaaagc ctgtatcgta acgggtgcta
    37981 tcgcggtgga ccggtattga tgagcgcgct ttccggcatc gacatggccc tttgggatat
    38041 caagggcaaa gtcgccaata tgcccgttca tgccctgctg ggcggtgccg ttcgtgaccg
    38101 ggttaaaagc tattgctgga taggtggtga tcgaccgacc gacctgatcg gcggggcgca
    38161 aaaattgcgc gagaagggct ataaggccct taaattcaat atttgcagtg aaatgcaaat
    38221 tattgattct tatcgtaaaa ttgaccaaag cgttcaaatg ttaagcgaac tgcgcgccgc
    38281 aattggcaat gacatggatt ttgcctgtga ttttcatggc cgggttcata tgcccatggc
    38341 acgcattctt ctgcgcgaaa ttgaacatct gcacccgatg tttgttgaag acgcggtttt
    38401 atcaacacaa atcgatgaaa tggccgattt gtcgcgcgca acaaccattc cgctcgcaat
    38461 tggcgaaagg ctgcattcgc ggtttgattt ccgggcggtt tttgaaaaac gcgctgccag
    38521 tgtgatcaac cccgataccg cccatgtcgg tggcatttca gaaatggtcc ggatcggtca
    38581 ttgggccgaa gcctatgaca tcgccctcgc cccccattgc ccgcttggcc ccattgccct
    38641 tgccgcctgc ctgcaggtcg atgccatttg ccataatgcc ttcatccagg aacaaagcct
    38701 gggcatgcat tataataccg gcggtgatct gaacgattat ttgctgccat cctcgcgcta
    38761 tcaggtcatt gatggctatt tgccgatccc gcaggggccg ggattgggta ttgaagttga
    38821 tgaagaccac atcatcgccc aatccaccat cggtcaccgc tggcgcgccc cactttggcg
    38881 ccacgaagac ggctccatcg ccgaatggta aaacgatgtt aacgccaata acatcacttg
    38941 acgcaatttc tgggtaaaga tcaaaaaaaa catccccatc actttgctca gcgatgggga
    39001 tgttttctaa aaccgtccgg cttaatcgcg gcgcgaggtc gcgtattttt cagattgctc
    39061 ataatagtca tcaaagccga tgcgcttgcg caattcttcc cagctcatca gcatattatc
    39121 acgcggttga ccggccttga gcaattgcag ggtttccacc attgccttca tggccgatgc
    39181 catcaatgac agtggatatg ctgcaatctt aaatccgatt tcacgaagtt cttcgggtga
    39241 aagatcaggt gtttcaccgc cctcaaggat attggccatc tttgcccccg gaagggcacc
    39301 gcaaatggtg cgcatttcat caaccgattt gggtgcttcc acaaacagga tatcagcccc
    39361 cagttcggca aatttcgcgg cacggtcaat ggcttcggcc agcccgtgtt catggcgcgc
    39421 atcggtccgc gccaaaatca ggatatctgc cccggcctca cgggcatcaa ctgcggcacg
    39481 gatacggtca aacgcttcat cacgtccaac aacttccttg cccttggtat ggccgcagcg
    39541 tttcggggca acctggtctt cgatcatgac cgcggcacaa ccagccttgg caaaaccctg
    39601 caccgtgcgg cgtacattca tggcattgcc ataacccgta tcgccatcgc caatcacggg
    39661 gatggaaacc gcatcggtaa tgttacgggc ctggtccagc acctcgccat aggacataag
    39721 ccccaggtcc ggcgcaccaa tgcgcgccgc cgccgccgag aaacccgaca taaaggtcag
    39781 gccaaatccc tgctgttcaa tcagttttgc cgaaagcgca tcaaaacagc agggcatggt
    39841 aatcagttcg tcacgcgcta gcatggcgcg aagcgtattg gcaggtgtca tgttcttcac
    39901 agtttaaacg gaatataaag ggcgaggtcc ggccacacat aaaggatcac cgcggtcaaa
    39961 aacatcagca ggatgaaggg gaaaaccccc tttgacactt cgccaagcgg tgttcgcgcg
    40021 accgattgaa tgacataaag attcatgccg acaggggggg taatcagcgc acattcaacc
    40081 atgatcacca tgtaaacccc aaaccagatc ggatcaatcc ccagcgccat ggccgcaggc
    40141 aacagaaccg gcgtcatgat cagcaccatg gaaagggctt caaacaccag ccccatcaac
    40201 agcagcacaa ccgataccac cagcacaaaa ccaagctggg tatcaacatt gtggctgatc
    40261 agaaccgaaa tatcctgcgg gatacgataa agcgtgatcg ccttgccaaa aaccttggcc
    40321 ccggcaatga tcagaataac cgaaaccgtc gttgccatgc tttcaaaggc ggctttttta
    40381 atgccatccc atcccaaagc aggcatgaca acacgaatat tcatgcgcgt caccaggcgg
    40441 tcaaacccgc gaaacagccc aaaaacaatg atcggcagca ggaagtaacc aatgatcggc
    40501 ccctgcccct taaagaccat gtaataaacc gcatcggcca aaatcatgct ggcaggcaag
    40561 cgcaaaaccg gaatggtaat ggcaagcgct gccgcaaagc caatggcggc cgcctcggtc
    40621 ggggtgaagg caccaccata aataccggca ataatcaaaa ccgctagcaa aatggccgga
    40681 aacgccttaa aggttgccgc ccagcgttca ttccagttct ttttgggttc cggcacctgg
    40741 ccgccaaggc gggcataaat catcgaaaac actataaaca gcaccagcag ggcaatgccc
    40801 gggccaatac ccgccaaaaa cagcgaaata accgattctt cagtcacaaa gccataaatg
    40861 atcagcggaa tggacggcgg aataagaatt cccagcgtgc cgccagctgc cagcaggcca
    40921 taaacaaagc gcttattata accccgattg atcatttccg ggatggcaac cgtgccaatc
    40981 gttgccgccg tggcaacaga cgaccccgaa atggcagcaa aaacaccaca ggacaaaatg
    41041 gttgcaaccg caaggccacc gggccaatgc ccgacccagg cactaacagc ggcaaacaga
    41101 tccttgccaa caccggcctg caacaggacg ttcgacatca gcaaaaataa cggcacagcc
    41161 agcagaataa agccatcaag cgtggataaa atggcctggg gcgccatcag cggcgaaaaa
    41221 ccgcccagca ccagcatggc taggccaagc ccacccagcg caaaggccac cggcacacga
    41281 ataagcagaa ccgcaaacag ggcgatcagt gtcagaacaa tggtcattca tgcgcccctt
    41341 gcggaatttc ccggcccatc acaacgcgga taatttcaat cagtgactgg atcgccagca
    41401 aggcaaagcc cacaaatacc ggcaattcgg aaatccaggt tggcaaatcc agcatcgaac
    41461 ccgtggtacg gccccgttcc aggctttcaa agaaaatgcc aaagcctttc cacgccacca
    41521 caatcgagaa gatgcccaca acggccattg ccagaatttc aagaacacgc tgcatggtgg
    41581 ggctgcatag acgggttatg gcatcaaccg caatatggcg gcgtgttgcc agcgcccagg
    41641 gcatcccaat tagcgatccc caaatcaggc atagctgcga aagctctgcc gcccagatgg
    41701 tgggacgaac gaaaaaatac cgcgcaacca cttcccagct cagcatcagc cctgccgcaa
    41761 caaacagcag cgcccctatc caggccagtg caacaataaa tcggttatac attgtgggac
    41821 ttcgcgcgaa ggccggcaca accgggaccc ccgcctttcc tgtggtggaa attttaaata
    41881 tcttggtcat ctcagacagg aacaccgcca gcagcaaaaa tactggcggc ggtgttccgt
    41941 caactggtcg tcaaaccgtc agatcaaagc tttttggcag cgtcaaaaac ctgcttgccc
    42001 agatcaccgg cactgttgag gaaggaatca taaaccggct gcgaaactgc acgccactgt
    42061 ttcacttctt catcggtcgg ggtgtaaata gtcatcccgg cttcttcgga ttccttgaat
    42121 gcggctgctt caatcgcact catacgatca cgcacgtctt tttcggcatc gcgggaggct
    42181 tcggtaatga tcgcgcgctg gtcatcggtc aggccgttcc agaaatcggt attgatcatg
    42241 accaggaatt caacgtcagc catattggtg atggtgacgg tatccatgac ttcccacaat
    42301 ttacgcgatt tcacaccgga aatgccggtc atgccgatat caaccgtgcc acgctgatag
    42361 gcaagatact gttccgaacc ggaaatcagg gtcggtgcgc caccggctgc ttcggtgaat
    42421 tcacccagcg atttgccaaa tacacggact tttttgcctt caaggtcttt gggggtgtgg
    42481 atcggcgcac ccttggacag catgatggtg ccgccataag cctgccacca caaaacggtc
    42541 gaaccggtat cagcaatagc tttgtccagc gggccacgaa cgggcgaacc cggtgcaact
    42601 gccgcacgaa ccttggcttc ggaatccagc acgaacggct gatagaatac gtcaactgcc
    42661 ggcacatcac ctgcatagcg cgtcagcgaa gccgaaccca tttcaatgga gcccgaccca
    42721 acggcgctgg ggatttcctt gtctttataa agggtggcag aatcataaat ttcaacggcg
    42781 atattgccgt ttgatttttc ttcgacttct tttttaaaca gttcaaggtt ctgaacaata
    42841 tgacttttgg gcggaagctg ggatgcgatg cgcaatgtta catctgcggc ctgtgccgcc
    42901 ccgctaaccc ctaccgcagc catcaaggca gcgatcatgg caattttttt catgatgaac
    42961 gtcctctggg ttttttaatt acaatcaatt ccaa
//
