LOCUS       NZ_CP024200            29113 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete
            sequence.
ACCESSION   NZ_CP024200
VERSION     NZ_CP024200.1
KEYWORDS    RefSeq.
SOURCE      Thalassospira marina
  ORGANISM  Thalassospira marina
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
            Thalassospiraceae; Thalassospira.
REFERENCE   1  (bases 1 to 908044)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Biodiversity and function of Thalassospira species in the
            particle-attached aromatic-hydrocarbon-degrading consortia from the
            surface seawater of the China South Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 908044)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2017) State Oceanic Administration, The Third
            Institute, Room 329, Daxue Road 184, Xiamen, Fujian 361005, P.R.
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3
            Genome Coverage                   :: 300
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002844375.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 04:06:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,760
            CDSs (total)                      :: 4,670
            Genes (coding)                    :: 4,656
            CDSs (with protein)               :: 4,656
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 2 of 14
            Pseudo Genes (incomplete)         :: 13 of 14
            Pseudo Genes (internal stop)      :: 4 of 14
            Pseudo Genes (multiple problems)  :: 4 of 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:03:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 456996
            Orig. end                         :: 486109
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024200.1.
            Bacteria and source DNA available from Dr. Zongze Shao; The Third
            Institute of State Oceanic Administration, Daxue Road 184#, Xiamen,
            Fujian, 3610015, China, Tel: 86-592-2195321.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..29113
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..29113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="neighbouring"
                     /product="azole-containing-RiPP"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..25047
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25047
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15047](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15047)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(75..87)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(988..1494)
                     /locus_tag="CSC3H3_RS22245"
                     /old_locus_tag="CSC3H3_22180"
     CDS             complement(988..1494)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007091560.1"
                     /locus_tag="CSC3H3_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22180"
                     /product="N-acetyltransferase"
                     /protein_id="WP_101286576.1"
                     /transl_table=11
                     /translation="MIVIDREGAYSHIEREKLLDRVMGPDRFKKSSELIRAGRLPADGL
                     AFVAHDGKHMIGTVRLWNVDAGNAGFALMLGPLAVEKAYNGSGVGAGLMYAAINAAYDS
                     GHRAILLVGDPQYYARFGFTAAPAAGLAMPGYFDRHRFLGLNLDEDVLGGTSGVLSPTG
                     RYQTH"
     gene            complement(1506..2639)
                     /locus_tag="CSC3H3_RS22250"
                     /old_locus_tag="CSC3H3_22185"
     CDS             complement(1506..2639)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002966479.1"
                     /locus_tag="CSC3H3_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22185"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_101286577.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 1.3e-56, bitscore:
                     187.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 4.3e-09,
                     bitscore: 32.0, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQRIIDFLAQNRPEGPCLVVDLDVVQRNYETFTRALPDSRIFY
                     AVKANPAPEVLSLLADLGSNFDTASVPEIEMAMAAGATPERISFGNTIKKERDVARAYE
                     MGVRLFAVDCVEEVEKIARVAPASRVFCRILTDGAGAEWPLSRKFGCAPTMALEVLQHA
                     HHMGLDAYGVSFHVGSQQCNLDAWNTALAEASMIFRTLAEKGIVLRMVNMGGGFPTRYL
                     RDVPATEAYGAAIIDALHNHFGNHMPETIIEPGRGMVGDAGVIKAEVVLISRKHEDDPV
                     RWVYLDIGKFGGLAETMDEAIRYPITTIHDGGDVAPCVLAGPTCDSADVLYEKKPYDLP
                     IALTIGDEVLIEATGAYTTTYASVAFNGFSPLAAYII"
     misc_feature    3002..3013
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.36"
                     /tool="antismash"
     gene            3328..3780
                     /locus_tag="CSC3H3_RS22260"
                     /old_locus_tag="CSC3H3_22195"
     CDS             3328..3780
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_22195"
                     /product="hypothetical protein"
                     /protein_id="WP_101286579.1"
                     /transl_table=11
                     /translation="MAESPDRQPPAIVMPDRPMMADDWSDGLPVIYNQVAGCLNADPSP
                     PARVVDAGQGNDGQIVIDMMGDSGTYFRCQTDPAGKSKPVLFRQEMPANLPGPVYTATP
                     YPPPKSPQAGICYEHYPVTDHTGWQLGWLSYAREGDNCSTASIAKP"
     misc_feature    complement(3358..3371)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     gene            3876..4295
                     /locus_tag="CSC3H3_RS22265"
                     /old_locus_tag="CSC3H3_22200"
     CDS             3876..4295
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008388363.1"
                     /locus_tag="CSC3H3_RS22265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22200"
                     /product="DUF3830 family protein"
                     /protein_id="WP_101268591.1"
                     /transl_table=11
                     /translation="MTKLKITAGPFVFDAKLETGAAPKTCAAFVERLPFISKVVHVRWS
                     GEGVWMPLGDYQFGVDYENHTSYPAPGQIILYPGGISETEILLAYGGVHFASKVGQLAG
                     NHFITITSNLEDVVKLGKMTLWEGAQDIRFELVSD"
     gene            complement(4329..4610)
                     /locus_tag="CSC3H3_RS22270"
                     /old_locus_tag="CSC3H3_22205"
     CDS             complement(4329..4610)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007754307.1"
                     /locus_tag="CSC3H3_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22205"
                     /product="hypothetical protein"
                     /protein_id="WP_245881400.1"
                     /transl_table=11
                     /translation="MTQTNERPDPAHRPQRCESNAKAMRPLRMRLAIVMIACVYPLVTM
                     LIYLIAPFTQGWQIWHQTMLLTPATVLSIVFVINPLVFKYFGRYINAM"
     gene            complement(4623..5234)
                     /locus_tag="CSC3H3_RS22275"
                     /old_locus_tag="CSC3H3_22210"
     CDS             complement(4623..5234)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1193: glutathione S-transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012455657.1"
                     /locus_tag="CSC3H3_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22210"
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="WP_101286581.1"
                     /sec_met_domain="GST_N_3 (E-value: 1.7e-17, bitscore: 59.1,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 5.4e-12, bitscore: 41.3,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLYQFKAGTNPRRVSIYLAEKGLDIPRYELDYANREHKSPAYLA
                     LNAAGRAPALVTDSGEVIADSAAIVEYLEELYPANSMIGNDAATRAKVRALERLGTDLV
                     VRAQIWLWNETNNFPFMQARPSSEMAGIMFQHVTEILDALEKSIGDYEFLAGNRPTIAD
                     FTVFAIFQTARERFNLPFGNRHPRLDAWFANFRKRPSADY"
     gene            5398..6213
                     /locus_tag="CSC3H3_RS22280"
                     /old_locus_tag="CSC3H3_22215"
     CDS             5398..6213
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="CSC3H3_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22215"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_157831991.1"
                     /transl_table=11
                     /translation="MRLNRLTRSGEKEELAKFLRFCRERISPEQLGLPATRRRRTKGLR
                     REEVATLAGVGLTWYTWFEQGRDIQVSDDFLLRLSRGLRLNRAEQEHLFALSQRQAVRA
                     IAPAIDLPPSLIGIVKRLPDAAYVLDNCWDVLAYNDAALTLFEDLAADRPNMLRIVFFS
                     NAYRQKIRDWSFAARLVFLKARHDFLTGGRSPILESLLDDVMGASPEAKEWWNDPEALR
                     IGDTKIELNDPLTGWITFQLSIFSYEDHPNLRLVVYTNEHCSPFTDDQN"
     cand_cluster    5976..29113
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5976..29113
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[15975:19113](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(15976..19113)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="2"
     gene            complement(6352..7998)
                     /locus_tag="CSC3H3_RS22285"
                     /old_locus_tag="CSC3H3_22220"
     CDS             complement(6352..7998)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008890140.1"
                     /locus_tag="CSC3H3_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22220"
                     /product="U32 family peptidase C-terminal domain-containing
                     protein"
                     /protein_id="WP_101286583.1"
                     /transl_table=11
                     /translation="MSDQSRRSELLMPAGSLEKLKIAVLYGADAVYMGTPDLSLRVKSQ
                     MSLDDVVDGIEFAHQHGVRVYLTLNLFSHNKDISKLPEYVETVRKVQPDGLIVADPGVF
                     MFVREQAPEIPLHVSTQANVCSWQSVKFWQSIGAKLVVLGREVSYEELTEIREKCQDIK
                     IEAFVHGSMCMTYSGRCLLSNFMAERGANQGACANSCRWKYKVHMKLKDGTVKELNLTE
                     ENMELFDFFLEEEMRPGELMEIQEDERGSYILNSRDLCIMPKLEDYLKIGVDSLKVEGR
                     GKSPYYAGLVARAYRMAIDDWYDDPENWSPEPYMKELATIPNRGYTLAFHEGRLTNYAH
                     GYDSSSNVSDWEFAGLIERVEDDAFIVSVKNRLLAGDVLEIVPPKGRQTIFIRMYEFID
                     ANTGKVGEAVHAGAKPMVRIPFSLLEQEDPEYLRTAFPPMTIIRKEKALTPDEWQRMKL
                     DQEGHKIEMGKGNPERYDAKREALQDALDERQKDRTFRTPRVGTQGCCGRGCNGCLIFW
                     HDPQYAKAREILAKRKQGEMLEHDGKTVAAE"
     CDS             complement(8140..8313)
                     /gene="allorf_465136_465309"
                     /locus_tag="allorf_465136_465309"
                     /protein_id="allorf_465136_465309"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVAMQRYPSKISNGLGCRNRRPFRPPVPTDQTMPYSNTRPAMRWR
                     VFCCGIWRTACG"
     CDS_motif       complement(8206..8313)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVAMQRYPSKISNGLGCRNRRPFRPPVPTDQTMPYS"
                     /locus_tag="allorf_465136_465309_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(8140..8205)
                     /prepeptide="core"
                     /locus_tag="allorf_465136_465309_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="2464.9"
                     /monoisotopic_mass="2463.2"
                     /core_sequence="NTRPAMRWRVFCCGIWRTACG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVAMQRYPSKISNGLGCRNRRPFRPPVPTDQTMPYS"
                     /leader_location="[8205:8313](-)"
     gene            complement(8330..9958)
                     /locus_tag="CSC3H3_RS22290"
                     /old_locus_tag="CSC3H3_22225"
     CDS             complement(8330..9958)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="CSC3H3_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22225"
                     /product="S53 family peptidase"
                     /protein_id="WP_101286584.1"
                     /transl_table=11
                     /translation="MTSIRLSGTAHPVFQQSPKALARAGDERVKFNIHLAPGSAKNITD
                     AKLANLKNKGRRKTRATLQQNLHPSLDAIQQVTQWATTAGLQPINNAGIPGILSFEASV
                     AAINASFGITLATVVVNGVACFGHGEDIHIPKELSDIIDFVSGLDTIPLAAPHLRHQPN
                     HDQISEIATAMTQTAQNGTQTAQGDYPTSYDATTIAEMYDFPPKLDGTGQRIAIVELGG
                     GYTQADIDAYFAKYNLKTPAITAIGVAGAENNPGQNSNNDSEVVLDIQIAGAVAPGAEF
                     FVYFVPNYSYSFALALQTILGDKTNNPDIISISWGGSEETYPAKAREMTQKYCKLAAAH
                     YVTVLSSSGDHGANNGGSAPTTNFPACIPEILGCGGTQIETKNNRIISEVVWDNLAFSW
                     GGASGGGISSSFAVPTYQQNLPLPQSPNGQPGRGVPDVSANADPLTGYKYYRNGKWSFV
                     GGTSAVVPLWAGLVARLNQGLGEPVGNINSELYKCAATGVGFSNIIEGNNGYYHAGPGW
                     NACTGLGSPEGEKLYAYFHTQAGNA"
     gene            complement(10001..12760)
                     /locus_tag="CSC3H3_RS22295"
                     /old_locus_tag="CSC3H3_22230"
     CDS             complement(10001..12760)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CSC3H3_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22230"
                     /product="cytochrome P450"
                     /protein_id="WP_101286585.1"
                     /sec_met_domain="PF00881 (E-value: 1.3e-12, bitscore: 43.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 1.1e-23, bitscore: 79.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAITTQHSRNTATAPLIVLADHAAIVSDINDNPLVAYPGGQVPF
                     TGMPLSVVNAITSLANTDGYNLDQLATTVAATGQATDVAFLYFMLETLGKRALLQYSLQ
                     IDGQKRLSVQPMRYGELFTPARLDANSSYQLSRFAHCRQHEGAFILETPLSGIKISIHQ
                     PDLAQILHTLSSPLSVQHTCNHLKNINPRIISDIFAYLLAARAICPINADGIAEEDTHP
                     ALRQWEFHDLTFHAHTRSGSHSDPLGAYFPFDGIIPAPPALKPLPEGEVVHLPCPETTP
                     PHQEPGFQTVMEQRHSWRHHDDENPITLEELGTFLFRTARIRALYDISPERGQKYQESN
                     RPYPNGGAMYELELYVTVRLCQGLEAAIYYYDAAAHQLIRVDTSETHRQKLLRQASISA
                     AGAPEPQILFTMTSRFERMSWKYRSMAYATTLKHVGVLMGSMYLVATAMGLAPCALGNG
                     LSELKLDTNALDYFSESPVGDFMLGRKGKQPEDTSPDISKGNTVDQTRTPATKGRKASP
                     SLAKATKSFLEQPVNHPDPGGLYRRLLDEEPIHRTMSGAWLISSYDDTAKLISHPAMSV
                     NHQATVGTRPLAQSPDIAHYLAQMMSMRDPPDHDRIATHIRGAFKPAAINALRPQIDDL
                     INEALQPGLDARRFDIIADLGRDLPVNVTCAMLGIPRTDWPKLQGWTALLTSQIDNFDQ
                     SASSLEHVTRDIHAFAEYIHILLSERQARPRPNDVLSDIVAANQVLSWQEMTAQCMLLL
                     IGGRDTVTNMIGNSLLLLIQHPDQLEKLRQNRSLIPNTVEECLRFESPIRLAVRTLKHP
                     LTYRHHAFMPGEVIMFLLAAANRDAAHFAEPDTFMIERPQKPHFAFGRGTHFCIGHQLA
                     RVEGASILTWLLKHCRSIEPLDDLATPAWSNCLPFRGLTHLNVRFNAA"
     gene            complement(12786..15047)
                     /locus_tag="CSC3H3_RS22300"
                     /old_locus_tag="CSC3H3_22235"
     CDS             complement(12786..15047)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="CSC3H3_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22235"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_101286586.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 6e-17, bitscore:
                     57.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 3.4e-19,
                     bitscore: 64.2, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 1.1e-11,
                     bitscore: 40.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 7.2e-94, bitscore: 310.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 9.2e-83, bitscore:
                     273.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDVKKPRIKPYFHVQVLPPEGVYLLSETGSIILKGERNCALIPL
                     MDGTRTIDDIAETVQDQCSFAEVLYVVDMLHEKQYIDDASTAGNSADRNFWQALTLEPE
                     TARQKLAATKVRVVTLGQAQAAPFISALATFNIAVTQEDNWDMGVVITDDYLHSGMEAF
                     NKQALAAGKPWIAVKPHGVISWVGPVFKPSEGGCWACLAQRLRLNREVDTYLQNSFDQK
                     NPFPISRAFNGASVEIGIQLAALQTAKWIAGGIENSNSGKMFTLNMLNLHASHHTLVPR
                     PQCPVCGCGDGDVGEMPAAPTLSHRAKTYTVDGGHRAKSPQQLLNDFSHHISPYIGAVR
                     ELEKMDEGLHEILPAYGAGHNFAVRTINLTFLRRGLRTRSAGKGTTDTQAKASALAEAL
                     ERYSGLYFGNENRITASYAELGSRAIHPNDCMLYSDQQYEDRDAWNSRDLKFAVVPQRF
                     DENASIEWSPVWSITENRYKYLPTGYLYYNYPLGNDFQYWADSNGNAAGTCLEDAILQG
                     AMELVERDAVAMWWYNRFQRPALDLDSFQDDYVNKLRQKYKELNRPLWVLDITNDLGIP
                     TFVAVSRRIDKPCEDILCAFGSHYDPRLALRRALTEMNQFLHAVVDMKADGSGTYRFPE
                     DENHHWWKTATLENQPYLAPLPNSPLRRLQDFPIREHDDLLEDVLAFQELIEDRGMELL
                     FLDQTRPDIDLPVVKVIVPGLRHFWARYAPGRLFTVPVTLGWQERELAEHELNPIPCFL
                     "
     aSDomain        complement(14754..15026)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CSC3H3_RS22300_Goadsporin_CD_RRE.1"
                     /evalue="4.40E-13"
                     /identifier="RREFam013.1"
                     /label="CSC3H3_RS22300"
                     /locus_tag="CSC3H3_RS22300"
                     /protein_end="98"
                     /protein_start="7"
                     /score="40.1"
                     /tool="antismash"
                     /translation="RIKPYFHVQVLPPEGVYLLSETGSIILKGERNCALIPLMDGTRTI
                     DDIAETVQDQCSFAEVLYVVDMLHEKQYIDDASTAGNSADRNFWQA"
     aSDomain        complement(14757..15032)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CSC3H3_RS22300_NHLP_CD_RRE.1"
                     /evalue="2.30E-18"
                     /identifier="RREFam015.1"
                     /label="CSC3H3_RS22300"
                     /locus_tag="CSC3H3_RS22300"
                     /protein_end="97"
                     /protein_start="5"
                     /score="57.0"
                     /tool="antismash"
                     /translation="KPRIKPYFHVQVLPPEGVYLLSETGSIILKGERNCALIPLMDGTR
                     TIDDIAETVQDQCSFAEVLYVVDMLHEKQYIDDASTAGNSADRNFWQ"
     aSDomain        complement(14805..15029)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CSC3H3_RS22300_Cyanobactin_D_RRE.1"
                     /evalue="1.30E-20"
                     /identifier="RREFam007.1"
                     /label="CSC3H3_RS22300"
                     /locus_tag="CSC3H3_RS22300"
                     /protein_end="81"
                     /protein_start="6"
                     /score="64.2"
                     /tool="antismash"
                     /translation="PRIKPYFHVQVLPPEGVYLLSETGSIILKGERNCALIPLMDGTRT
                     IDDIAETVQDQCSFAEVLYVVDMLHEKQYI"
     gene            complement(15214..15531)
                     /locus_tag="CSC3H3_RS22305"
                     /old_locus_tag="CSC3H3_22240"
     CDS             complement(15214..15531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004272680.1"
                     /locus_tag="CSC3H3_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22240"
                     /product="thiocillin family RiPP"
                     /protein_id="WP_217351177.1"
                     /transl_table=11
                     /translation="MAMDLKAKHEQTKDYPHRLGRLIVKTWADPVFKKKAETDPRGALA
                     DFGIHVPADVPVDKLPLPPRPADLSDEQLNQANANDGSCAGSAGSASCPSCSAGTAASA
                     H"
     CDS             15696..15806
                     /gene="allorf_472692_472802"
                     /locus_tag="allorf_472692_472802"
                     /protein_id="allorf_472692_472802"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAEFQNACAHTQRVGDALKALPGPCVDREKGNKTLM"
     CDS_motif       15696..15767
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAEFQNACAHTQRVGDALKALPGP"
                     /locus_tag="allorf_472692_472802_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15768..15806
                     /prepeptide="core"
                     /locus_tag="allorf_472692_472802_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="1391.6"
                     /monoisotopic_mass="1390.7"
                     /core_sequence="CVDREKGNKTLM"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAEFQNACAHTQRVGDALKALPGP"
                     /leader_location="[15695:15767](+)"
     misc_feature    complement(15772..15785)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     CDS             15814..15942
                     /gene="allorf_472810_472938"
                     /locus_tag="allorf_472810_472938"
                     /protein_id="allorf_472810_472938"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGSFFPRLGDPFEELPHVLGGNMLHFLCSVLRLGDMILNCSY"
     CDS_motif       15814..15876
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGSFFPRLGDPFEELPHVLGG"
                     /locus_tag="allorf_472810_472938_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15877..15942
                     /prepeptide="core"
                     /locus_tag="allorf_472810_472938_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-0.50"
                     /molecular_weight="2422.9"
                     /monoisotopic_mass="2421.2"
                     /core_sequence="NMLHFLCSVLRLGDMILNCSY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGSFFPRLGDPFEELPHVLGG"
                     /leader_location="[15813:15876](+)"
     gene            complement(15976..19113)
                     /gene="lanM"
                     /locus_tag="CSC3H3_RS22310"
                     /old_locus_tag="CSC3H3_22245"
     CDS             complement(15976..19113)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CSC3H3_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22245"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_101286587.1"
                     /sec_met_domain="DUF4135 (E-value: 3.4e-68, bitscore:
                     225.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-06, bitscore:
                     22.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDQKMNNDAPNRDWECLKSIIARAAPPNERANSSYLEAIDTGDPA
                     LIDQRYQLWLEAATDGDEAQADTILAALGISKDELRAGFKNVRCLDNADYPDWINALVD
                     FIAICRNLSSIPAHPLSGTHGNDENFAIFKHIHTYLRRVGHAILGKTTVKSNIVITETA
                     RNGFSDMFANRLLNVLGQSIQYELNIAALQNQLTGAAGQYLAKVPDISARGWIERFDRL
                     PGLAYVLGITCAHWRQSVSELLDRLNEDRQILANQLFDGAEITELCEFSGDAGDPHDKG
                     RSVAILQFNNGRKVVYKTKDLRGSKAFMDLIHCLNTATPALKLPTRTILCRGKYGWDEF
                     IEAKECNTSLEVEHYFIRMGMYVRLLQLCEGRDFWLDNLVAQGAFPHFIDLETLLQGRE
                     ITPKGWVGNSSALKALFDESIVPTAAVASHVYLKPGTPAEDMGSLTPARRLRTPFRAQG
                     SPALDPLFTQSEPDSLVEWRPPAFAPVLNGKPANVSENWQAVLAGYRSMQDVLIKMAPT
                     LLEREGKVLADLKAPVRHIVRDTWSCYHLIQMMLSPRVLDDGITRDIAIARLYRELSPD
                     KALNARTKVIHAEITALCRLDIPLFQSLPEQDQILSSDLSLLGRYFDGTAQDRLKTRLA
                     HITQFDLDHHCDILLSCLETGAAPAPPTVFAPTSSCPKSVDWLETADLIGQDIMNNAVA
                     DENGHPCWFGLGYDPVNQVQILQELRRNMLSGTLGLAQFFAALHSKTRNPLYRDLSLDI
                     IQPFSNQADPVATENTPQIIHRHSPLGRFFGVQGEILAGLFCAHHLGNSDLAQHYNQLL
                     ASLPITAPSQCDADTHSALIDIGNLSGLLDALSHVSSDPNYVGNIETISGKLLSAVMHC
                     DPNDPGFDIVDAQIKTVPSPLVLTVVALERLSQTHKKTAPNFTPALNKLNDFFAPKIIA
                     GHLSDMSLAGLLESRQLRPLVIQSAQAKSKFFDDSISCLDLLVCCRLALALFKQCRQEL
                     YLNQARTAAWTLLQRKKQSYSWFQDRFAADRHNLSLHWGLPAIALTFIELAECDLT"
     gene            complement(19378..20898)
                     /locus_tag="CSC3H3_RS22315"
                     /old_locus_tag="CSC3H3_22250"
     CDS             complement(19378..20898)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1153: Amino acid carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009817469.1"
                     /locus_tag="CSC3H3_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22250"
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="WP_101286588.1"
                     /transl_table=11
                     /translation="MFSLKWIPAATAGVTILSLSPMAQAQESGMDQAINETIAPISDVI
                     AGTIFYSVQFGDIEFPLIVGWLVIAATIFTLYFGFVQFRMFGHAISLVKGDYSDPNDAG
                     EVSHFQALATALSGTVGLGNIAGVAVAISIGGPGATFWMILAGLLGMASKFTECTLGVK
                     YRNEYADGRVSGGPMYYLTKGLAEQGKPGLGRVLAVLFSICCIGGAVGGGNMFQANQAF
                     QQIVNVTGGEQSFIADSGWLFGLVMAAIVAMVIIGGIKSIAKVTEKIVPFMAVIYVLSG
                     LVIIGMNIEHVGDAFYRIFDGAFTGAGIAGGMVGALIQGFKRAAFSNEAGIGSAAIAHS
                     AVRTKEPITEGYVALLEPFIDTVVICTMTAIVITISGQLQTDLTGVELTSAAYATAFTW
                     FPLILALAVVLFAFSTMLSWSYYGLKAWTYLFGEGKGKETAFKAFFCICVVIGASMNLD
                     PVIDFSDAMIFAMALPNVIGLYFLMPIVKREATQYWQKIDRGEIRKVK"
     gene            complement(20987..21421)
                     /locus_tag="CSC3H3_RS22320"
                     /old_locus_tag="CSC3H3_22255"
     CDS             complement(20987..21421)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008890135.1"
                     /locus_tag="CSC3H3_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22255"
                     /product="universal stress protein"
                     /protein_id="WP_101268577.1"
                     /transl_table=11
                     /translation="MSDHPILVGFDGTDAAHRAVEFAGARAEAEGCPIHIAYILEWSPY
                     SFLSAQELEERHQRRTEELGRAETTLNPALEILRNRNISVTYEVRYGHSGELMCKIARE
                     KQATQIIIGRKGGSALGARLLGSLALTLVQAAPLPVTVVP"
     CDS             21434..21634
                     /gene="allorf_478430_478630"
                     /locus_tag="allorf_478430_478630"
                     /protein_id="allorf_478430_478630"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDWEMCSVPSERGKAGSVRAGKVSWDVRPNRSGHRCHPCARRFLT
                     AGARAGGCHILICRLQSFASP"
     CDS_motif       21434..21589
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDWEMCSVPSERGKAGSVRAGKVSWDVRPNRSGHRCHPCARRFLTAGARAGG"
                     /locus_tag="allorf_478430_478630_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21590..21634
                     /prepeptide="core"
                     /locus_tag="allorf_478430_478630_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="1567.9"
                     /monoisotopic_mass="1566.8"
                     /core_sequence="CHILICRLQSFASP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDWEMCSVPSERGKAGSVRAGKVSWDVRPNRSGHRCHPCAR
                     RFLTAGARAGG"
                     /leader_location="[21433:21589](+)"
     CDS             21538..21762
                     /gene="allorf_478534_478758"
                     /locus_tag="allorf_478534_478758"
                     /protein_id="allorf_478534_478758"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPPLRPAVFNGGGEGRRMPYIDLPIAVICVSLTGGHMPCAEYPGG
                     FAPWCRSDSFKQAKPWIAQMNAFGCNLFR"
     CDS_motif       21538..21642
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MPPLRPAVFNGGGEGRRMPYIDLPIAVICVSLTGG"
                     /locus_tag="allorf_478534_478758_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21643..21762
                     /prepeptide="core"
                     /locus_tag="allorf_478534_478758_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="4444.1"
                     /monoisotopic_mass="4441.0"
                     /core_sequence="HMPCAEYPGGFAPWCRSDSFKQAKPWIAQMNAFGCNLFR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPPLRPAVFNGGGEGRRMPYIDLPIAVICVSLTGG"
                     /leader_location="[21537:21642](+)"
     misc_feature    21641..21654
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     misc_feature    complement(21857..21871)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.15"
                     /tool="antismash"
     misc_feature    21880..21895
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.43"
                     /tool="antismash"
     misc_feature    complement(21980..21994)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            22170..23516
                     /locus_tag="CSC3H3_RS22330"
                     /old_locus_tag="CSC3H3_22265"
     CDS             22170..23516
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008890133.1"
                     /locus_tag="CSC3H3_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22265"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_101286590.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.6e-36, bitscore:
                     119.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQQAKPALQTGQMSAVAIADNFSDLHPPFSTLQAMAESNRCLY
                     CYDAPCVTACPTSIDIPSFIRKISTGNPDGAAKTILSANIMGGTCARACPTEVLCEQAC
                     VRNVAEDEAVEIGSLQRYAVDHLMARNLSHPFKRAEATGKKIAVIGAGPAGLSCAHRAA
                     MLGHDVTVFEAKPKPGGLNEYGLAAYKMTNDFAQREVEFLLGIGGITIEYGKALGRDIS
                     LADVKASFDAVFVGVGLGATNNLGLAGEAASGVDDAIDFIENLRQASDKSTMPVGNAVV
                     VIGGGNTAIDAAVQAKRLGADEVTLVYRRGPENMSATEFEQELAKINGVIVRYWAKPVE
                     IKANGRLMGMVFEKTALDASGKLVGTGETFEVKTDQVLKAIGQKIKTDDLAGMEISGGK
                     IVVDENYQTTAAGIFAGGDCIKSGEDLTVQSVEDGKCAAIAIDAFLKNA"
     gene            23543..24820
                     /gene="preA"
                     /locus_tag="CSC3H3_RS22335"
                     /old_locus_tag="CSC3H3_22270"
     CDS             23543..24820
                     /EC_number="1.3.1.1"
                     /GO_function="GO:0017113 - dihydropyrimidine dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_process="GO:0006210 - thymine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006212 - uracil catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="preA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007091546.1"
                     /locus_tag="CSC3H3_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22270"
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="WP_101286591.1"
                     /transl_table=11
                     /translation="MADLSCKIAGIDSLNPFWLASAPPTDKKYNVVRAFQAGWGGVVWK
                     TLGIDPPVVNVSSRYGAHHDQNRRLLGINNIELISDRPLALNLQEIRECRAEWPDHVII
                     GSMMAPIEERAWKDLAQQIAESGVHGLELNLGCPHGMCERGMGSAIGQVPEMVEQVTRW
                     VKEAVDIPVFTKLTPNITNILWSAEAALKGGADAVSLINTVNSIISVDLDQMVPEPMVD
                     GKGTHGGYCGSAVKPIALNMVAEIARTPETQALEISGIGGITTWKDAAEFMALGANAVQ
                     VCTAAMIYGFRVVDDLIDGMSQWMDDQGYTSVEQFTRKAVPQVANWNELNMNFDTKAVI
                     DPDKCIECGRCHIACEDTSHQAIAMNAKPEGGREFVVIDEECVGCNLCYHICPVPDCIT
                     MEPVKTDKPYMTWPQHPLNPMRDAAE"
     gene            24890..26167
                     /locus_tag="CSC3H3_RS22340"
                     /old_locus_tag="CSC3H3_22275"
     CDS             24890..26167
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008890131.1"
                     /locus_tag="CSC3H3_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22275"
                     /product="Zn-dependent hydrolase"
                     /protein_id="WP_101286592.1"
                     /transl_table=11
                     /translation="MTAASTARNLNINGDRLWDSLMEMAKIGKTAKDGVCRLALTDLDR
                     ESRDLFIKWCKDEGCSIRIDKMGNIFARREGKNPDLPPIVAGSHLDSQPTGGKYDGVYG
                     VLSGLEVIRTLNDAKYETEAPVEVVCWTNEEGSRFAPAMVSSGVFAKVFDLGYGHSRAD
                     IDGKTMGEELKRIGYMGDDEATIDAHPMGAYFEAHIEQGPILEDEGMDIGIVTDAQGQR
                     WYEITLTGVEAHAGPTPMTSRKDALLGAARIIELVNKIGLDRGPLACATVGMMQIHPNS
                     RNVIPGRVFLTVDFRHPDDAVLADMDAVLRKGVEDIKSGIGLECEFEQIFYYAPVPFDP
                     SCVDAVRKGAERGGYKAREIVSGAGHDACYLAQVTPTAMIFIPCVDGISHNEIEEVHKH
                     WSDAGGQVLLDAVLAKADEKPGEQAA"
     gene            complement(26265..27155)
                     /locus_tag="CSC3H3_RS22345"
                     /old_locus_tag="CSC3H3_22280"
     CDS             complement(26265..27155)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008890130.1"
                     /locus_tag="CSC3H3_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22280"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_101286593.1"
                     /transl_table=11
                     /translation="MGKKWGVAVLVLLAGGLSVSSTSNARVLQTQPGLNGSLANKASIS
                     SPFESANASATCTKLHITGAAGWEPISYQDKNGVAHGVSVDILREFTSSRGLELDVNLD
                     IPWNRGMLMLASGEIDAMAGAYFTEERDREFTYSQPYASDDIMVFQSAKRPFLVDHVRD
                     LIDRRGARPQGGSYGDFLDHYAEDYLDIIFSPTGNRILDLLTSNRVDYVMLGRFDGMAN
                     IINDNIGDQIRMVEKPLMQNPVMFMFSKKSPCRDLVPELDAFIEQLEQNGQLATMTQAH
                     LPKPDAQTAPAPTPE"
     gene            complement(27273..27914)
                     /locus_tag="CSC3H3_RS22350"
                     /old_locus_tag="CSC3H3_22285"
     CDS             complement(27273..27914)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011908485.1"
                     /locus_tag="CSC3H3_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_22285"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_101286594.1"
                     /transl_table=11
                     /translation="MTTTAKPANGAHKAAIRQENEVQILAAAERVFADYGFKGATTARI
                     AEVANVPKANVHYYFATKEALYRRVIENVCSQWLEAAMTFENTTDPATILRGYIEAKMD
                     LSRSTPYGSRVWAHEIVRGAKFSSDYISTTVKDWLDGRVRIIRRWIAEGKMDNVEPYSL
                     MYMIFATTQHYADFSSQIEIFNGNQALSDQQFAKAKENVVQIILKGIGLN"
     misc_feature    27946..27961
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: strong, score: 26.04"
                     /tool="antismash"
     misc_feature    complement(28082..28095)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.88"
                     /tool="antismash"
     CDS             28228..28332
                     /gene="allorf_485224_485328"
                     /locus_tag="allorf_485224_485328"
                     /protein_id="allorf_485224_485328"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MADDCNCLPICGYAMIDESSGACALEKPNRVRET"
     CDS_motif       28228..28293
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MADDCNCLPICGYAMIDESSGA"
                     /locus_tag="allorf_485224_485328_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       28294..28332
                     /prepeptide="core"
                     /locus_tag="allorf_485224_485328_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="1413.6"
                     /monoisotopic_mass="1412.7"
                     /core_sequence="CALEKPNRVRET"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MADDCNCLPICGYAMIDESSGA"
                     /leader_location="[28227:28293](+)"
     misc_feature    28509..28525
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.58"
                     /tool="antismash"
     misc_feature    29095..29104
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.75"
                     /tool="antismash"
ORIGIN
        1 tgccagtttt ggcgccacca aaaaggcggc atcggccact gcgggcggca ttgaataccg
       61 tttgatgctg gattttgcca aaggcaaata taaaaccggc gaaaagcgca tcaatgacca
      121 gcttagcgca cctgacaaac acgaaatcag cagtgcccag acccaggaga aactggtttt
      181 aacccgcctt aaaaccgaac tggcggcgac ggaaatgtct gaaccggatg gacgccagac
      241 cttcgtatgt gatgaccagt cgcgttttta tgcgaccttt aaccgcgaag atgaacaggt
      301 gcggatcgaa tttttgggcc gcgacccgat tttcctgccg caaaaaccgg cggcatcggg
      361 tttcctgtat ggcaatgatg attatgaaat gcgcggcaag ggccagaacg ccacctgggc
      421 aacgctggta gatggccgca aaaccggttg taccgtttcg gccgaaattg ccgggctggc
      481 actagcaccg ggtgatttcc cgacggtgaa tgtttcaacc ctgatgcaga cgggcaataa
      541 cgaatggacc cgtcattttg acgacatgat gcctgcgatc aaggcctgcc tggaacgccc
      601 ggtgggcgat ttgccatcgg tcctgaaagc ctggccgatg aaccatggta cggttggtgt
      661 acgcaccatt aacatcaatg gcgggcgcta tgactgcctg gcaccgtcaa ccggcttggg
      721 cgacatccat gtcgaggcgg ttgaaggcgc aaccaatgtg ttgccgggtg aacgtgatgt
      781 gctgtttacc ccggcatcgg gggcgtatcc ggataatgac tgttaccagc ataaaaagct
      841 gatgaaggat ggtgttttca ttggctggct gtcacgcaat gcctgccaaa gctgattatc
      901 catcggttaa ttgctgctga aacaaacaaa gccccgccgg atctggcggg gctttgtcgt
      961 ttgtggaacg ggcaaatgca gtgcgtatca gtgggtttga taacgtccgg tcggggacag
     1021 aacgccactg gtcccgccaa gaacgtcttc atcaaggttc aaacccagaa aacggtgccg
     1081 gtcaaaataa ccgggcatcg ccaggcccgc agccggtgcg gcagtaaagc cgaaccgggc
     1141 ataatattgt ggatccccaa ccagcagaat ggcccgatgg ccggaatcat aggcggcatt
     1201 gatggcagcg tacatcaaac cggccccgac cccggaacca ttataggctt tttccactgc
     1261 aagtgggcca agcatcaggg caaaacccgc attgcctgca tcgacattcc acaaccggac
     1321 agtcccgatc atgtgtttgc cgtcatgggc aacaaaggcc aacccgtcag ccggcaaccg
     1381 gccagcacgg atcagttcgg acgatttttt aaaccggtcc ggtcccatta cgcgatcaag
     1441 cagcttttcc cgttcgatgt gggaataagc accttcgcga tcgatcacga tcattgacgt
     1501 gatgcctaga tgatataggc agcgagcggc gaaaagccgt taaacgctac cgatgcatag
     1561 gtcgtggtat aggcaccggt tgcttcgatc agaacctcgt caccaatcgt cagggcgatc
     1621 ggcagatcgt agggtttctt ttcgtaaagc acgtcggctg aatcgcaggt cggaccggcc
     1681 agaacacacg gggccacatc gccgccatca tggatcgtgg tgatggggta gcgaatggct
     1741 tcgtccatgg tttcggcaag gccgccgaat ttgccaatgt cgagataaac ccagcgcacc
     1801 ggatcatctt cgtgtttgcg cgaaatcagc acgacttcgg ctttgatcac gccagcatca
     1861 ccgaccatgc cacggcccgg ttcgataatg gtttcgggca tgtggttgcc aaagtggtta
     1921 tgcagggcat caatgatggc cgcgccatag gcttcggttg ccggaacgtc acgcaggtaa
     1981 cgggtcggga aaccaccacc catattgacc atacgcagaa caatgccttt ttccgcaagg
     2041 gtgcggaaaa tcatcgatgc ttcggcaagt gcggtgttcc aggcatccag gttgcactgc
     2101 tgcgaaccaa catggaagga tacgccatag gcgtccaggc ccatgtggtg ggcatgctgc
     2161 agcacttcaa gcgccatggt cggtgcgcaa ccaaatttgc gcgacagcgg ccattcagca
     2221 ccggcaccat cggtcaggat gcggcagaaa acgcgcgaag ccggggcaac gcgggcaatt
     2281 ttttcaactt cttcgacgca atccacggcg aacagacgca cacccatttc ataggcacgt
     2341 gcaacgtcac gttctttttt gatggtgttg ccaaacgaaa tgcgttccgg ggtggcgcca
     2401 gcggccatcg ccatttcgat ttccggcacg gatgcggtgt cgaaattgct gccgaggtcg
     2461 gccagaaggc tcagaacttc cggtgccggg tttgctttga ccgcatagaa aatgcgggaa
     2521 tcaggcaggg cacgggtaaa ggtttcgtag ttgcgctgga ccacatcaag gtcaacaaca
     2581 aggcacggac cttccggtcg gttctgggcg aggaaatcaa taatacgctg cgttgccatg
     2641 ggggcgttct cccattccac tttaaagcgg catagcgaca cctgatgcat cctgacgcgg
     2701 tggaggcgta gaatgcggtc tatcgatatg ccagacgtga acacggatga tccggttcgc
     2761 ggatgttgcc tcgatatagg aatgggaagt tgccattccg cacggcgggc aatgatggtg
     2821 tgcctcttta gtgtctgcgg tatttggaca accgctggag accaaaaaag ccctacaccg
     2881 tcgttgcttt aagtaagtcc tacagggttc cttggcagga ccaccacagg cacgtgcgac
     2941 tttgggcaag ccgggattta cgcctgtttt atctttggcg caagcggttt ttttaatgcg
     3001 ggaaaatgtt ttttgtcatg gtccaaaaca ccgggtcaaa cccggcggat ccccttggtt
     3061 tctggcgtga ttttcatatt cccaactatc agaaaacagg ccttttttcg cgcaggggct
     3121 gtatcgttcg ccagtcttgc aaagccaatg gcttaacgac acataattgc catgcatcac
     3181 ggcaaatctg tatcccatgg tcatatgcag gcaaaaacgg ggcgttattt aatggtcgca
     3241 atccggaata gttccagagt ccaaattatc atcgcggctt tgtccccgct ggccatcggc
     3301 gcatgccaga ccaggacacc gcctgatatg gccgaaagcc ccgatcgcca gccacctgca
     3361 attgtgatgc ccgatcgccc gatgatggct gatgactggt ccgacggttt gcctgttatt
     3421 tataaccaag tcgctggttg cctgaatgcc gacccgtcac cgcctgcgcg tgtggttgat
     3481 gccgggcagg gcaatgacgg gcaaatcgtg atcgatatga tgggcgatag cggcacttat
     3541 ttccgctgcc agacggaccc ggcaggtaaa agcaagcctg ttttgtttcg tcaggaaatg
     3601 cctgcgaacc tgccaggtcc ggtttatacg gccacaccct atccgccgcc aaaatccccg
     3661 caggcgggca tatgttatga acattatcct gttaccgacc ataccggctg gcaactgggt
     3721 tggctcagtt atgccaggga aggggacaat tgcagtacgg catctattgc aaaaccgtaa
     3781 tgccggtggg gatcatgcat ctatcacatt gcctgcaggg cggtttggtc gttatcttgg
     3841 cggccattcc atgatgtgat gtgaaagata ccaaaatgac caaactgaaa atcacggcag
     3901 gcccgtttgt gtttgacgca aaactggaaa ccggggccgc acccaaaacc tgtgccgctt
     3961 ttgttgaacg cctgcctttc atcagcaagg ttgttcatgt ccgctggagc ggcgagggcg
     4021 tctggatgcc gctgggggat tatcagtttg gtgtcgatta tgaaaaccac accagctatc
     4081 ccgcaccggg gcagattatt ctatatcccg gtgggatcag cgaaaccgaa atcctgctgg
     4141 cttatggcgg tgtccatttt gcatccaagg tcggccagct tgccggcaac catttcatca
     4201 ccatcaccag caatcttgag gatgtcgtca aacttggcaa aatgaccctg tgggaaggcg
     4261 cgcaggatat tcggtttgag ttggtttccg attaaccaat attctttatt gggcggtacg
     4321 ttattccttt acatggcatt gatgtaccgc ccgaaatatt tgaagaccag tgggtttatg
     4381 acgaacacga tgctaaggac cgttgcgggt gttaataaca ttgtttgatg ccagatttgc
     4441 cagccttgcg tgaagggtgc gatcaggtaa atcagcatcg tcaccaatgg ataaacacaa
     4501 gcaatcatga cgattgctag tcgcatccgt aaggggcgca ttgcttttgc attgctttca
     4561 cagcgctgtg ggcgatgggc tggatcgggc cgttcatttg tttgcgtcac aagtttcgcc
     4621 gtttaatagt ctgcactggg gcgtttgcgg aaatttgcaa accatgcatc aaggcgcgga
     4681 tgccggttgc caaaaggcaa attaaagcgt tcacgtgccg tttgaaaaat tgcaaataca
     4741 gtgaaatccg caatcgttgg ccggttcccg gcaagaaatt cataatcacc gattgatttt
     4801 tctagggcat caagaatttc ggtgacgtgc tgaaacatga ttcccgccat ttctgatgaa
     4861 ggtctggcct gcataaacgg gaaattgttt gtctcattcc acagccatat ctgtgcccga
     4921 acaacaagat cggttcccaa tcgctcaagc gctcgaacct tggcccgtgt cgctgcatcg
     4981 ttaccaatca ttgaattggc ggggtacagt tcttcgagat actcaacgat tgcagcggaa
     5041 tccgctatta cctcgccgct atccgtgact aaagcgggtg cgcggccagc ggcgtttaac
     5101 gccagatatg cgggcgactt gtgttctcta ttggcgtaat caagttcgta gcggggaata
     5161 tccaatccct tttccgccaa atagattgaa acccgcctcg ggtttgttcc ggccttaaac
     5221 tgatagagta acatttataa tcatctttcc acagggtacg gagaaagcag gaagtatggc
     5281 caacgcaact tcctgcggtg cagggcgttt ccacgactgt aaatttagac ctcactttat
     5341 cctgttacta tatggtattt atgctgttac tatagtgatg gtaagcagga gggacttttg
     5401 cggttaaacc ggttgacgcg ctcgggtgaa aaagaggagc tggcgaaatt cttgcggttc
     5461 tgccgggaac gcatttcgcc cgagcagctt ggcctgcccg cgacacgacg gcgcaggaca
     5521 aaagggttgc gccgggaaga agttgccaca ttggccggcg tcggcttgac ctggtacacc
     5581 tggtttgagc aagggcgcga tattcaggtt tcggatgatt ttttgctgcg tctctcacgc
     5641 gggttgcggc ttaatcgtgc agaacaggaa catttattcg cactttcgca acgccaagcc
     5701 gtgcgtgcca ttgcgccagc gatagacctg ccaccaagct tgattggcat cgtcaagcgc
     5761 ttgcccgatg ctgcatatgt gctcgataac tgctgggacg tattggctta taacgatgca
     5821 gctttgactc tgtttgagga tttggcagcc gataggccta atatgctgcg gatcgtgttt
     5881 ttctcgaacg cgtatcgcca aaaaatcagg gactggtctt ttgccgccag attggttttt
     5941 ctaaaggctc ggcatgattt tttaacgggt ggacgcagcc ccattcttga gtcattgcta
     6001 gatgacgtga tgggggcttc tcctgaagcc aaagaatggt ggaatgaccc tgaagcattg
     6061 cgtattggcg ataccaaaat agagctgaac gatcccttaa cagggtggat caccttccag
     6121 ctaagcatat tttcatatga agaccacccc aatcttcgtt tggtggttta taccaacgag
     6181 cattgcagcc cttttaccga tgatcagaac tgatttcgga tttgattgtt tgttttcgcg
     6241 ttattgcaat ggggtgttgg cattgccttg ggcgtctttt gggggataaa aaaaacggca
     6301 gcaaaggaac cgatgctgcc gtttgatgtt tgagatgatg cgttaggtgg tttattccgc
     6361 cgccaccgtc ttgccatcgt gttcgagcat ttcgccctgt ttgcgtttgg cgaggatttc
     6421 gcgggctttg gcgtattgcg ggtcatgcca gaagatcagg cagccattgc agccacggcc
     6481 gcagcaccct tgcgttccga cacgcggggt gcggaaggtg cggtctttct ggcgttcatc
     6541 aagggcgtcc tgcagggctt cgcgtttggc gtcgtagcgt tccgggttgc ccttgcccat
     6601 ttcaattttg tgcccttcct gatccagctt catgcgctgc cattcatccg gtgtcagggc
     6661 cttttccttg cggatgatgg tcatgggcgg gaaggcggtg cgcagatatt ccgggtcttc
     6721 ctgttcgagc agggaaaacg gaatacgaac catcggtttg gccccggcat gaacggcttc
     6781 accaactttg ccggtattgg cgtcgataaa ttcatacatg cggataaaaa tggtctggcg
     6841 gcccttgggt gggacaattt ccagcacatc acccgccaac aggcgatttt tgaccgaaac
     6901 gataaaggcg tcgtcttcca cccgttcgat cagcccggca aattcccagt cggaaacgtt
     6961 gctggagctg tcataaccat gggcataatt ggtcaaccgg ccttcgtgga aggccagcgt
     7021 gtaaccccgg ttggggatgg tagccagttc cttcatatag ggttcgggcg accagttttc
     7081 ggggtcgtca taccagtcat caattgccat gcgataggca cgcgcgacca gcccggcgta
     7141 ataggggctt ttgccgcggc cttcgacctt caggctgtca acgccgattt taaggtaatc
     7201 ttccagtttc ggcatgatgc acagatcgcg cgaattgagg atgtatgatc cgcgctcgtc
     7261 ttcctgaatt tccatcagct cgccggggcg catttcttct tcgaggaaga aatcaaacag
     7321 ttccatattt tcttcggtca ggttcagttc cttgaccgtg ccgtccttca gcttcatatg
     7381 gaccttgtat ttccagcggc aactattggc acatgcgccc tggttggcgc cgcgttcggc
     7441 catgaagttg gacagcaggc agcgaccaga ataagtcatg cacatggagc catgcacaaa
     7501 ggcttcgatt ttgatgtcct ggcatttttc gcgaatttcg gtcagttcct cgtaggaaac
     7561 ctcacggccc agcaccacca gttttgcgcc gatgctttgc cagaatttga cggactgcca
     7621 cgaacagaca ttggcctggg tggaaacatg cagcggaatt tccggggcct gttcgcgtac
     7681 aaacatgaaa acgccgggat cggcgacaat caacccgtct ggctgaacct tgcgcacggt
     7741 ttcaacatat tccggcagtt tggaaatgtc cttgttgtgc gaaaacaggt tcagcgtcag
     7801 ataaacccgc accccgtgct ggtgggcaaa ttcaatgcca tccaccacat catccagcga
     7861 catctggctt ttgacccgca acgacagatc gggcgtgccc atataaacgg catccgcgcc
     7921 atacagcaca gcaattttaa gcttttccaa agagccagca ggcatcaaca attcggaacg
     7981 gcgcgattga tcactcatat cgtcggtctt tatttatgga atgcggggga attctctctc
     8041 gttctggcgc ggtcatatca taccttggca ccagattgcg cccaaaatta catatttcgc
     8101 gcaatttgcc taggcctgct gctgcagggc tgtattgaat cagccgcagg cagtccgcca
     8161 aatgccacag caaaacaccc gccagcgcat tgcagggcgg gtgtttgaat aaggcattgt
     8221 ctgatcagtt gggactggcg ggcggaatgg ccgtcggttt cgacatccta gaccattgct
     8281 gatcttggag gggtaccttt gcattgcgac caatcatgct gcccgcgggt taagcgttgc
     8341 cagcctgggt atggaaatat gcatacagct tttcaccttc gggggagcca aggccggtgc
     8401 aggcattcca accggggcca gcatgataat agccgttgtt gccttcgata atattggaaa
     8461 agccgacgcc ggtcgcagcg catttatata gctcggaatt tatattgccc acaggttccc
     8521 ccagcccttg attaagcctg gcaacaaggc cagcccaaag tgggacaacg gcactggtgc
     8581 cacccacgaa gctccattta ccgttacggt aatatttgta gccggttaaa ggatcggcat
     8641 ttgccgaaac atctggcacg ccccgtcccg gttggccatt cgggctttgt ggcaggggca
     8701 ggttttgctg ataagtcggg actgcgaacg aactgctgat gccgccacca gatgcccctc
     8761 cccacgagaa ggccagattg tcccaaacga cttccgagat gatgcgattg tttttggttt
     8821 cgatctgtgt gccgccgcag ccgagaattt cggggataca ggccgggaaa ttggttgtcg
     8881 gagcgctacc gccattattg gcgccgtgat ccccggacga ggacaggacg gttacataat
     8941 gggcggcggc aagcttgcag tatttttgcg tcatttcacg tgctttggcc ggataggttt
     9001 cttctgatcc cccccaactg atcgaaatga tgtccgggtt gtttgtttta tcgccaagaa
     9061 tggtttgaag tgccagggca aacgaatagc tgtaatttgg cacaaaatag acgaaaaact
     9121 ctgcccctgg tgcgactgcc ccggcaattt gaatgtcgag cacgacttcg ctgtcattat
     9181 tgctgttttg gccgggatta ttttctgcac cggcaacacc aatggcggta atagccggtg
     9241 tcttgaggtt atatttggca aagtaagcgt caatgtcggc ctgcgtgtaa ccaccgccca
     9301 attcaacaat cgcgatgcgc tgccctgtgc catccagttt tggcgggaag tcatacattt
     9361 cggcaatggt cgtggcatca tatgatgtcg ggtaatcgcc ctgtgccgtt tgggtgccgt
     9421 tttgggcggt ctgcgtcatt gccgtcgcaa tttcagaaat ttgatcatga tttggttgat
     9481 ggcgaagatg cggggctgcc aggggaatgg tatccagccc ggaaacaaag tcgatgatgt
     9541 cagaaagttc tttgggaatg tgaatgtctt cgccatgacc aaagcaggcc acaccattga
     9601 ccacgacggt cgccagcgta atgccaaagg aggcattgat ggcagcgacg gaagcttcaa
     9661 aagaaagaat gcctggaatg cctgcattgt tgatgggctg taacccggcg gtcgtggccc
     9721 attgcgtgac ctgctggata gcatccagcg aaggatgcag gttttgttgc aatgtcgcgc
     9781 gtgtttttcg ccgtcctttg tttttcaggt tggcgagttt tgcatccgta atgtttttcg
     9841 cgctacccgg cgcaagatgg atgttgaatt tgacacgttc gtcaccggcg cgggcaaggg
     9901 cttttgggct ttgttgaaag acgggatgcg ctgtaccgga aagccttata gaggtcatga
     9961 tggtgttccc tgatcctgat tttggctgag aagtaagatg ctatgccgcg ttaaaacgaa
    10021 cgttgaggtg tgtaagccct cgaaaaggca ggcagttgga ccatgctggc gtggctaggt
    10081 catcaagcgg ttcgattgag cggcaatgct taagtagcca ggttaaaatg ctggcacctt
    10141 caacccgggc cagttgatgg ccgatgcaaa aatgggtgcc gcgtccaaag gcaaaatgcg
    10201 gtttttgcgg gcgttcgatc atgaatgtgt cgggttctgc gaagtgcgcg gcatcgcgat
    10261 tggccgcagc aagcagaaac atgatgacct cgcctggcat gaaggcatga tgacgatagg
    10321 tcagggggtg tttcagggtg cgaacggcca gtcggatcgg gctttcaaag cgcaggcatt
    10381 cttcaactgt attgggaatg agagagcgat tttgccgtaa cttttccaac tgatcaggat
    10441 gctgtatcag caatagcagg ctgttcccga tcatgttggt cacggtatcc cggccaccaa
    10501 tcagaagtag catgcattgc gctgtcattt cctgccagga caggacctgg tttgctgcaa
    10561 caatatcgga cagaacatcg ttggggcgtg gacgggcttg acgctccgat aacaggatgt
    10621 ggatgtattc ggcgaaggca tggatgtcgc gtgtgacgtg ttcaaggctg ctggcagatt
    10681 gatcaaagtt atcgatttgg ctggtcagca atgcggtcca gccctgaagt ttgggccaat
    10741 cggtgcgtgg aatgcccagc atcgcacagg ttacatttac cggcaggtcg cgccccagat
    10801 cagcaatgat atcaaagcgg cgggcatcaa ggccgggttg caatgcttcg ttaatcaaat
    10861 cgtcgatttg tggcctaaga gcattgattg cagcgggttt aaaggccccg cgaatgtggg
    10921 tggcaatgcg atcatggtcg ggtgggtcac gcatggacat catttgcgcc agatagtgcg
    10981 caatatctgg tgattgtgcc aatggtctgg tgccgacagt tgcctggtga ttaacgctca
    11041 tggcgggatg gctgatcaat ttggctgtgt catcgtaact cgagatcagc catgcaccag
    11101 acatcgtgcg atgtatgggt tcttcgtcta gaaggcgacg gtataaaccg cctgggtccg
    11161 ggtgattgac gggttgttca agaaacgact ttgttgcttt ggccagggat ggggacgctt
    11221 ttcgtccttt tgtggctggc gtccgggttt ggtccacggt attgcctttg gagatatcag
    11281 gggatgtgtc ttctggctgt tttcctttgc ggcccagcat gaaatcccca accggagatt
    11341 cagaaaagta atccagcgcg ttggtgtcga gtttcaattc cgaaaggcca ttgcccagcg
    11401 cgcagggtgc cagccccatt gcggttgcaa ccagatacat agaccccata aggacgccga
    11461 catgtttcaa cgtcgtggca taggccatcg aacggtattt ccatgacatg cgttcaaagc
    11521 gcgacgtcat ggtaaataaa atttgcggtt ctggggctcc ggcagcggag attgacgcct
    11581 gccttagcaa tttttgccgg tgggtttctg atgtatcaac ccggattaat tgatgcgcgg
    11641 cagcgtcata ataataaatc gcagcttcaa gcccctgaca cagccgaacc gtgacataaa
    11701 gttccaattc atacatggca ccgccattgg ggtaggggcg gttgctttcc tggtattttt
    11761 gtccgcgttc tggcgaaata tcataaaggg cgcgtattct ggccgtgcga aacagaaagg
    11821 tgccaagctc ttccagcgtg atggggtttt catcgtcatg gtgtcgccag gaatggcgtt
    11881 gttccatcac ggtttgaaaa ccgggctcct gatggggggg cgttgtttcg gggcagggaa
    11941 gatgaacaac ctcgccctcg ggcaggggtt ttagggcggg cggtgccggg atgatgccgt
    12001 caaaggggaa atatgcccct aacgggtcgc tatggcttcc gctgcgggtg tgggcgtgaa
    12061 aggtaagatc gtgaaattcc cattgccgca aggcaggatg ggtgtcttct tcggcgatgc
    12121 catctgcatt gatcgggcat attgcacgtg ccgccaacag atatgcgaag atgtcggaaa
    12181 tgattcttgg attgatattt ttcaggtgat tgcaggtgtg ttgaaccgat aaaggcgacg
    12241 acagcgtgtg aaggatttgc gccaggtcgg gctgatggat tgaaattttt atccccgaca
    12301 gcggtgtttc aaggataaag gcgccttcat gctggcgaca atgtgcgaag cgtgaaagct
    12361 gataactgct gtttgcgtca agccgcgcag gggtaaacag ctcgccatat cgcatcggct
    12421 gaactgacag tcttttttgg ccatcaattt gcaatgaata ttgaagcagg gcgcgcttgc
    12481 cgagcgtttc gagcataaaa tacagaaatg caacgtcagt agcctgtccg gttgcggcga
    12541 ctgttgtggc aagctgatca agattgtatc cgtcggtatt tgccaaagaa gtaatggcat
    12601 taacgacgct taaaggcatg cctgtgaacg gcacctgacc gcccggatat gcaaccagag
    12661 gattatcgtt gatatcggaa acgattgctg cgtggtcagc cagcacgatt aacggagctg
    12721 tggctgtatt tcttgaatgt tgcgtggtta tggcggtcat ggctgtttcc tatgcctggc
    12781 aagttttaca aaaagcacgg gatcggattc agctcgtgtt cggcgagttc gcgttcctgc
    12841 caacctagcg tgaccggaac ggtaaacagg cggcctgggg catagcgggc ccagaaatgg
    12901 cgtaatcccg ggacaatcac ctttacaacc ggcaggtcaa tatccggccg ggtttggtct
    12961 aaaaacagca attccatgcc gcgatcttcg atcagttcct gaaaggccag tacgtcctcc
    13021 agcaggtcgt catgttcgcg gatcgggaaa tcctggagcc ggcgcagggg gctattgggt
    13081 aagggggcca gataaggctg attttcaagg gtggccgttt tccaccaatg atgattttca
    13141 tcttccggga agcgataggt cccgctgcca tctgccttca tatcgacaac ggcgtgcagg
    13201 aactggttca tctcggtcag agcacggcgc agtgccaagc gtggatcata gtgcgagcca
    13261 aaggcacaca agatgtcttc gcaaggttta tcaatgcggc gcgatacagc gacaaaagtg
    13321 ggaatgccca ggtcgttggt aatgtcgaga acccataggg ggcggtttag ttccttgtat
    13381 ttttggcgca atttgttgac gtaatcatcc tggaaactat cgagatccag ggctgggcgt
    13441 tggaagcggt tataccacca cattgccacc gcatcgcgtt cgaccagttc catcgcgccc
    13501 tgcaaaatgg catcttccag gcaggtgccg gctgcattgc catttgaatc cgcccaatac
    13561 tgaaagtcat ttccaagcgg gtaattgtaa tacagatacc cggttggcaa atatttgtag
    13621 cgattttcgg tgatcgacca aaccgggctc cattctatac tggcattttc gtcaaagcgt
    13681 tgcggaacaa cggcaaattt taaatcccgg ctgttccaag catcccggtc ttcatattgc
    13741 tggtcgctat aaagcatgca gtcattggga tgaatggcgc gagatcccaa ttctgcgtag
    13801 cttgccgtga tccggttttc attgccaaaa tacaggccgg aatagcgttc cagggcttcg
    13861 gcaagggcgc tggccttggc ctgggtatcg gttgtgcctt tgcccgccga gcgtgttcgt
    13921 aaaccacgcc gcaaaaaagt aagattgatg gtgcgtacgg caaaattgtg ccctgcgcca
    13981 taggcgggca atatttcgtg tagcccttcg tccatttttt caagttcgcg aacggcaccg
    14041 atataggggc tgatgtgatg ggaaaaatca ttgagaagct gttgcgggga tttggcacga
    14101 tgaccaccgt ccacggtgta ggttttagcc cgatggctaa gggtgggggc ggctggcatt
    14161 tcgccgacat cgccatcgcc acaaccacaa acagggcatt gtggacgggg aaccagggtg
    14221 tggtgacttg catgcaggtt cagcatgttc agggtgaaca ttttgcccga attgctgttt
    14281 tcgatgccgc ccgcgatcca ttttgcggtt tgcagtgccg cgagttgaat gccgatttca
    14341 acactggcgc cattaaaggc ccgactgatc ggaaacggat ttttctggtc gaaactgttt
    14401 tgtaaatacg tgtcaacttc gcggttcagg cgcagccttt gcgccaggca ggcccaacat
    14461 ccaccctcgg acggtttgaa aaccgggccg acccaactga tgacgccatg tggtttgacc
    14521 gcgatccacg gtttgccagc ggccagggcc tgtttgttga aggcttccat cccggaatgc
    14581 aggtaatcgt ctgtaatgac gacccccata tcccagttat cttcctgggt aacggcaatg
    14641 ttaaaggttg ccaatgccga aatgaacggg gccgcttgtg cctgccccag cgtaacaacc
    14701 cgaactttgg ttgcggccag cttttgccgt gctgtttcgg gttcaagggt taatgcctgc
    14761 caaaaattac ggtcggccga atttccggct gtgctggcat catcaatata ctgtttttcg
    14821 tgcagcatat cgacgacata gagcacctcg gcaaagctgc attggtcttg tacagtttcg
    14881 gcaatgtcat caattgtgcg cgtgccatcc atcaagggga tcagcgcaca atttcgttca
    14941 cctttaagga tgatgctgcc ggtttcagac agcagataaa cgccttcggg cggaagaacc
    15001 tggacatgaa aataaggttt tatgcgcggc ttttttacgt caggcatctt acaccctgtg
    15061 cgttgaacat gaaggaaaag ggatttcagg cagtgcgcgc catttggtga tcaggcaatg
    15121 cggatacatg ctgaatggca ggtgcaattt ggcactttcg agaaggtgcc aaattgcgaa
    15181 ggtcatgtga ttttgcgctg agtaataatg cgcttagtga gcagaggcag ccgtaccggc
    15241 actgcaactc gggcaggacg cagaaccggc agaacctgca cagctgccat cattggcatt
    15301 tgcctggttc agctgttcgt cgctgagatc tgctgggcgc gggggcagcg gcaacttgtc
    15361 gacaggaaca tcggccggaa catgaatgcc aaaatcggcc agcgcgccgc gcgggtcggt
    15421 ttccgccttt ttcttgaaaa ccgggtctgc ccaggttttt acaatcaagc ggcccagtcg
    15481 gtgcgggtag tctttggtct gttcgtgttt tgctttaagg tccatcgcca ttttatgctc
    15541 tcctgtgtaa tgttatgggt ttcctcaatg gcgcagtaca gggtcattcc gggaatagcg
    15601 attgcgtgat gcaggtgctg tttccgatga tgtgcacgac gtcatcaagc cgggtgcagg
    15661 cacgcctaaa tcaactttaa attgtaattt taggtgtggc tgaatttcaa aatgcctgtg
    15721 cgcatacgca gcgtgtaggt gatgcgctca aggcattgcc agggccatgt gttgatcggg
    15781 aaaaaggaaa taaaactttg atgtaaagta tctttgggtt cctttttccc ccggttaggc
    15841 gatccctttg aagaattgcc ccatgttctg ggtggcaata tgctgcattt tttgtgtagc
    15901 gttctccgcc ttggggatat gattttgaac tgttcttatt aagacgggaa cgcggtgggg
    15961 ttgtgatctg aaattttagg tcagatcaca ttcggcgagt tcgatgaagg tcagcgcgat
    16021 ggcgggaaga ccccaatgga gcgacaggtt gtgcctgtct gcggcaaatc tgtcctggaa
    16081 ccagctatag gactgttttt ttcgttgcag taatgtccaa gcggcagtgc gggcttggtt
    16141 taaatacagt tcctgtcggc actgcttgaa cagtgccagt gccagacggc agcacaccaa
    16201 aagatcaagg caggaaatgc tgtcatcaaa aaacttggat ttagcctgcg cggattgaat
    16261 aacgagcggg cggagctgcc tgctctcaag caacccggca agggacatgt ctgaaaggtg
    16321 tccagcaatg atctttggcg caaaaaaatc attcaactta ttaagggcgg gagtgaagtt
    16381 tggtgcagtt tttttgtgcg tttgcgaaag ccgttccagg gcaaccactg tgagaaccag
    16441 aggagagggc acagttttta tctgtgcgtc cacaatatcg aaccctgggt cgtttggatc
    16501 gcaatgcatg actgctgata gcaatttgcc actgattgtt tcgatatttc cgacataatt
    16561 tgggtcagag gatacatggc tgagggcatc gagcagaccc gataaattac cgatgtcaat
    16621 gagggcgcta tgcgtatcag catcgcattg tgacggggcc gttatgggca ggcttgccaa
    16681 taattgattg taatgctgcg cgaggtctga attaccaaga tgatgtgcgc aaaataaccc
    16741 ggcgagaatt tcaccctgaa cgccaaaaaa ccttcccaat ggtgaatgac gatggatgat
    16801 ttgcggtgtg ttttccgtcg cgacagggtc tgcttggttt gaaaaaggtt ggataatgtc
    16861 aagcgagaga tcgcgataaa gtggattgcg cgtttttgaa tgcaaagctg cgaaaaactg
    16921 tgccaacccc aatgtgcctg acagcatgtt gcggcgtagt tcctgcaata tttgcacctg
    16981 attgacagga tcatatccaa ggccaaacca gcacggatgc ccattttcat ctgctacggc
    17041 attgttcata atatcctgcc cgatcagatc ggccgtttcg agccagtcca cggattttgg
    17101 acatgatgaa gttggtgcaa acacagtggg tggcgctggg gctgcaccgg tttcgaggca
    17161 agaaagtagt atgtcgcaat gatgatcaag gtcaaactgg gtgatgtggg caaggcgggt
    17221 ctttaagcgg tcctgggctg tgccgtcgaa atatcggcct aatagtgaca gatcggatga
    17281 caggatttga tcctgttcgg gaagtgattg aaacagggga atgtcaagac gacaaagagc
    17341 agtgatttcc gcgtgaataa cctttgttcg ggcattcagt gctttatcgg gggataattc
    17401 gcgatacagg cgcgcaatgg caatatcgcg tgtgatgcca tcatcaagta cccgcggtga
    17461 aagcatcatt tgtatcaggt ggtagcaact ccaggtgtcg cgcacgatgt gtcgcactgg
    17521 tgcttttaaa tcagccagta ctttgccttc acgttctaat aaagtcggtg ccattttgat
    17581 caggacatcc tgcatcgacc ggtatccggc cagaacagct tgccagtttt cactgacgtt
    17641 ggcgggcttg ccattcaaaa cgggtgcaaa agcaggcggc cgccattcga ccaggctgtc
    17701 gggttctgat tgtgtgaata acgggtccaa cgccgggctg ccctgcgcgc gaaatggcgt
    17761 tcgtaaacga cgggcgggtg tcagggagcc catatcctcg gcaggtgtgc ccggttttaa
    17821 ataaacatgg ctggcaacag cagcagttgg cacgattgat tcatcaaaca gggccttcag
    17881 tgcgctgctg ttgccgaccc aacccttggg tgtgatttcg cgtccttgca gcagggtttc
    17941 cagatcgatg aaatgtggaa acgccccttg cgccacgaga ttatcaagcc agaagtcgcg
    18001 tccctcgcac agttgcagaa gacgaacata catgcccatg cggatgaaat aatgctcaac
    18061 ttccagggaa gtattgcatt ctttggcttc gatgaattcg tcccagccat atttgccccg
    18121 gcaaagaatg gtgcgtgtgg gcaatttcag tgcaggtgtt gccgtattaa gacaatggat
    18181 taaatccatg aaggcttttg aaccgcgaag gtccttggtt ttgtatacga ctttacggcc
    18241 gttattaaat tgcaggatgg caactgatcg tcccttatcg tgcgggtctc ctgcatcacc
    18301 cgaaaattcg caaagctctg tgatttctgc gccgtcaaac agctgattgg ccagaatctg
    18361 cctgtcctca ttcaggcggt caagcagttc agaaacagat tgtcgccagt gggcgcaagt
    18421 aatgccgagc acatatgcaa gtcctggcaa cctatcaaac cgttcaatcc agccccgcgc
    18481 gctaatatct ggcaccttcg ccaagtattg cccggcagca ccggttaact ggttctgaag
    18541 tgcagcaatg ttcaattcat attggatcga ctgccccagc acatttaaca aacggtttgc
    18601 aaacatgtca ctgaagccat tacgcgccgt ttcggtaatg acgatgttcg atttaacggt
    18661 tgtttttccc agaattgcat ggccaacgcg gcgcagatat gtgtggatat gtttgaaaat
    18721 cgcgaaattt tcgtcattgc catgcgtgcc ggataatgga tgtgccggga tcgaagagag
    18781 attgcggcaa atggcaatga aatcgaccag cgcatttatc cagtcgggat aatctgcatt
    18841 atcgagacag cggacatttt tgaaaccggc tcgcagttcg tctttgctga tgccaagggc
    18901 ggctaaaatt gtatcggctt gtgcttcgtc cccatctgtg gccgcttcaa gccataattg
    18961 gtatcgctgg tcgatcaggg ctggatcgcc tgtgtcaatg gcttccagat aggaggaatt
    19021 cgcccgctca ttggggggcg cggcgcgggc gatgatggat tttaggcatt cccagtcacg
    19081 atttggcgca tcattgttca ttttttggtc catgcgaaca tgcctgttgg atggcaagtc
    19141 ggaggacctg acagccaatt gcgggcactt atgtacggcg atgttttaac cccggaagaa
    19201 acagattttt ctaattgcga ggttgcgcag tttgatgggg ctgcattcga ggacgtacaa
    19261 agagtgtctt ttgtgatgca aagtctgtgg gggagggacg caaggctggt gaacggggct
    19321 ggtatgtttg gcgagcttgt ggggcgacgg cgttgcatcg ccccacaaat gtcgaggtta
    19381 tttaaccttc ctgatctcgc cgcggtcgat tttttgccag tactgggtgg cttcgcgttt
    19441 gacgattggc atcaggaaat aaaggccgat cacgttgggc agggccatgg caaagatcat
    19501 ggcatcggaa aagtcgatga cgggatccaa attcatgctt gcgccaatga ccacgcaaat
    19561 gcagaaaaat gccttgaatg ccgtttcctt gcctttgcct tcgccaaaca gataggtcca
    19621 ggctttcagc ccgtaatagg accaggacag catggttgaa aaggcaaaca gaacaacagc
    19681 cagtgccaaa attagcggga accacgtaaa ggcagttgca taggccgccg atgtcagctc
    19741 gaccccggta aggtcggttt gcaactggcc ggaaatggtg atgacaattg ccgtcatggt
    19801 gcagatgaca accgtatcaa tgaagggttc cagcagggcg acatacccct cggtgatggg
    19861 ttccttggtg cggacggcgg aatgcgcaat ggcggcagag ccaataccgg cttcgttgga
    19921 aaaagccgcg cgcttaaagc cctggatcag cgcgccaacc ataccaccgg caatacctgc
    19981 gccggtaaag gcgccatcaa aaatgcggta aaaggcatcg ccgacatgtt cgatattcat
    20041 gccgataatc accaaccccg aaagcacata aatcaccgcc atgaaaggca cgattttttc
    20101 cgttaccttg gcgatggatt tgatgccgcc aataatgacc attgccacaa tggccgccat
    20161 caccaggcca aatagccagc cgctatcggc gataaagctt tgttcgccac cggtaacatt
    20221 aacgatttgc tggaaggcct gattggcctg aaacatgttg ccgccgccaa ctgccccgcc
    20281 aatgcagcaa atggaaaaca gaacggcaag gacgcggccc agacccggtt taccctgttc
    20341 ggcaaggccc ttggtcaaat aatacatcgg cccgcccgat acccggccat cggcatattc
    20401 gttgcgatat ttaacgccga gcgtgcattc ggtgaacttg gatgccatgc ccaacagccc
    20461 ggccaatatc atccagaaag ttgcaccagg cccaccaatc gagatcgcaa cggccacccc
    20521 ggcaatattg cccagcccga ccgtgcctga aagagcggtt gccagtgcct gaaaatgcga
    20581 aacttcgccc gcatcatttg ggtcggaata atcgcccttc accagtgata tggcgtgccc
    20641 aaacatgcga aactgcacaa agccgaaata aagcgtgaaa atggtagccg cgatcaccag
    20701 ccagccgacg ataaggggaa attcgatatc gccaaattgc acgctgtaaa aaatagtacc
    20761 ggcgatcaca tcggaaatcg gggcgatggt ttcgttaatg gcctggtcca tgccgctttc
    20821 ctgggcctgt gccattggcg aaagggataa aatggtgaca ccggccgttg cggcaggaat
    20881 ccattttagc gaaaacatga ggtgctcctg atcttgcttt tttgtttgcc cgtatttttg
    20941 gcggcattgc cgcatttcgg tgccgttcag tgccggttgc tatgcatcat ggaacaacgg
    21001 tgacgggcag gggcgcagcc tgaaccagtg tcagggccag gctgccaaga agccgtgcgc
    21061 caagggccga tccacccttg cggccaatga tgatctgggt tgcctgtttt tcacgggcga
    21121 ttttgcacat cagttcgccc gaatgcccgt agcggacttc gtatgtcacg ctgatgttgc
    21181 gattgcgcag aatttccagc gcggggttca gggtggtttc cgcccggcca agttcctcgg
    21241 tgcggcgctg gtggcgttct tcaagttcct gcgcggaaag gaagctgtaa ggcgaccatt
    21301 caaggatata ggcgatgtga atggggcatc cttcggcttc ggcgcgtgcg ccggcaaatt
    21361 caaccgcgcg gtgcgcggcg tcggtgccgt caaacccgac taatatgggg tgatcggaca
    21421 tgtctgttgc tccatggatt gggaaatgtg cagcgttccg tctgagagag gaaaggcagg
    21481 atctgtccgt gccgggaagg tgtcgtggga tgtgcgacca aaccggtcag gccatagatg
    21541 ccacccttgc gcccggcggt ttttaacggc gggggcgagg gcaggcggat gccatatatt
    21601 gatttgccga ttgcagtcat ttgcgtctcc ctgaccggcg ggcatatgcc ttgcgctgaa
    21661 tatccgggcg gttttgcacc ctggtgtcgt tctgattctt tcaaacaggc aaaaccgtgg
    21721 attgcgcaga tgaacgcctt tggttgtaat ttgttccgat aaaactatca gggatttagt
    21781 ctgaaattag accgaaacac gaaataactg cgcaaatcca attaaaacag cgggcttttc
    21841 accgatttaa ccggtctgaa aatgggttta aaattaatct tgaccaaatg atcaggattg
    21901 gtcatcctat aggggtcaga gagaggctcc tgaccgtgta tgcaaagtta aaagacaaaa
    21961 acacggcagg ataaaaggga tcgacagccc tgatcgcaaa aatgcgacgg gattgttgta
    22021 aaacgccagg aatacacatt gccggatatg tcaggggtgg cagggtaaac catgccatca
    22081 aggcccgtga tgtatctgcg cgttgtattt ctggtttcat gtctctcgct ggcgcaggag
    22141 aggacgcctt tacggcaggg agacatgaaa tgacgaccca gcaggcaaag cccgctttgc
    22201 aaaccggcca gatgtcggcc gttgccatcg ccgacaattt ttccgatctg cacccgcctt
    22261 tttccacctt gcaggccatg gccgaaagca accggtgcct ttattgttat gatgcgccct
    22321 gtgtcacggc gtgcccgaca tcgattgata ttccaagttt tattcgcaaa atcagcaccg
    22381 gtaacccgga cggggcggca aaaaccattt tgtcggccaa tatcatgggc ggtacctgtg
    22441 cccgcgcctg tccgaccgag gttctgtgtg agcaggcctg tgtgcgcaat gttgccgaag
    22501 acgaagccgt cgaaattggc agcctgcagc gctatgccgt tgaccattta atggcgcgca
    22561 acctgtcgca tccgtttaaa cgcgcagaag ccacgggcaa aaaaattgcc gttattggtg
    22621 ccggtcctgc cgggcttagc tgtgcgcacc gtgcagccat gctgggccat gatgtgacgg
    22681 tgtttgaagc gaaaccaaaa ccgggcggcc ttaatgaata tggccttgcg gcctataaaa
    22741 tgaccaatga tttcgcccag cgcgaagttg aattcctgct tggtatcggc gggattacca
    22801 ttgaatatgg caaggcgctg ggccgcgata tttcacttgc cgatgtcaaa gcatcctttg
    22861 atgccgtttt tgttggtgtg ggccttggcg caaccaataa tctgggcctt gccggtgaag
    22921 ccgccagcgg cgttgatgat gcgattgatt ttatcgaaaa tctgcgccag gccagcgata
    22981 aatccaccat gccggtgggc aatgcggttg tggtgattgg cgggggcaat accgcgattg
    23041 atgccgccgt gcaggcaaaa cgcctggggg ctgacgaagt aaccctggtt taccgtcggg
    23101 ggccggaaaa tatgtccgcc accgaattcg aacaggaact ggccaaaatc aacggcgtga
    23161 tcgtgcgtta ttgggccaaa ccggtcgaga tcaaggccaa tggccgcctg atgggcatgg
    23221 tgtttgaaaa aaccgcgctg gatgccagtg gcaagctggt ggggactggc gagaccttcg
    23281 aggtcaaaac cgatcaggtt cttaaggcga ttggtcagaa aattaaaacc gatgatcttg
    23341 ccgggatgga aatttccggg ggcaagattg tggtggatga aaattaccag acgacggcgg
    23401 caggcatttt tgccggtggg gactgcatca aaagcggcga ggatttgacc gtgcaatcgg
    23461 tcgaggatgg caaatgtgcc gccatcgcca ttgatgcctt tttgaaaaac gcctgagccc
    23521 gcgcccgcca aggagagaga acatggctga tttaagctgc aaaattgccg gtattgatag
    23581 ccttaacccg ttctggctgg catccgcacc gccaacggac aaaaaataca atgtcgtgcg
    23641 cgccttccag gccggttggg gtggcgttgt gtggaaaacg ctgggtattg acccgcccgt
    23701 ggtcaatgtg tcgtcgcgct atggcgcgca tcatgaccag aaccgccgcc ttttgggcat
    23761 caacaatatc gaactgattt ccgaccgacc attggcactc aaccttcagg aaattcgcga
    23821 atgccgggcg gaatggcccg atcacgtgat tatcggttcc atgatggcgc caattgaaga
    23881 acgcgcctgg aaggacctgg cccagcagat tgccgaaagc ggcgttcacg gcctggaact
    23941 gaatttgggt tgcccgcatg gtatgtgcga acgtggtatg ggttctgcca ttgggcaggt
    24001 gcccgaaatg gtggagcagg tgacacgctg ggtcaaggaa gcggtcgata ttcccgtttt
    24061 caccaaactg acgcccaata tcaccaatat cctgtggtcg gctgaagcag cgttaaaggg
    24121 cggggcggat gccgtttcgc tgattaacac tgttaactct atcatctcgg tcgatcttga
    24181 tcagatggtg cccgagccga tggttgatgg caaaggaacc catggcgggt actgcggatc
    24241 ggcggtgaag ccgattgcac tgaatatggt ggcggaaatt gcccgcacgc cagaaaccca
    24301 ggcactggaa atttcgggca ttggcggcat tactacctgg aaagacgccg ccgaatttat
    24361 ggcgctcggc gccaatgcgg tgcaggtgtg tacggcggca atgatttatg gtttccgcgt
    24421 tgtcgacgat ttgattgacg gcatgtcgca atggatggat gaccagggtt acaccagtgt
    24481 cgagcagttt acccgcaagg ccgtgccgca ggtggcgaac tggaacgaac tgaatatgaa
    24541 tttcgatacc aaggccgtga ttgacccgga caaatgtatc gaatgtggtc gctgccatat
    24601 cgcctgtgaa gatacatccc accaggcgat tgccatgaat gccaagcccg aaggcgggcg
    24661 cgaatttgtc gtgattgacg aggaatgtgt gggttgtaac ctgtgttacc acatctgtcc
    24721 ggtgcccgat tgtatcacga tggagcctgt caaaaccgac aagccctata tgacctggcc
    24781 gcagcatccg ctcaacccca tgcgtgacgc cgccgaatag gcgcagcaac cctgcaaatt
    24841 gtgcattcat ttgcatttat atgccccaca tatgaaagga ctttgattta tgactgctgc
    24901 gtcaaccgcc cgtaacctca atatcaatgg cgaccgcctt tgggatagcc tgatggaaat
    24961 ggcgaaaatc ggcaaaaccg ccaaggatgg ggtctgccgc ctggccctga ccgatctgga
    25021 ccgcgaaagc cgtgatttgt tcatcaaatg gtgcaaggac gagggctgtt cgatccggat
    25081 tgacaagatg ggtaatatct ttgcccgtcg cgaaggcaaa aaccccgact tgccgccgat
    25141 tgtcgccggc agccaccttg atagccagcc gaccggtggc aaatatgatg gtgtttatgg
    25201 ggtgttaagc gggcttgaag tgatccgcac cctgaatgat gccaaatacg aaaccgaagc
    25261 cccggtggaa gttgtgtgct ggaccaatga ggaaggatcg cgctttgccc cggcaatggt
    25321 gtcttcgggt gtgtttgcca aggtgtttga cctgggatac ggccattccc gcgcggatat
    25381 cgatggcaaa accatgggcg aagagctgaa gcgcatcggc tatatgggtg atgacgaggc
    25441 cacgattgat gcccatccga tgggggccta ttttgaagcc catatcgaac aggggccgat
    25501 ccttgaagat gaaggcatgg atattggcat tgtcaccgat gcgcaaggcc agcgctggta
    25561 cgaaatcacc ctgacagggg tagaagccca tgccggacca accccgatga cgtcacgcaa
    25621 agatgcgctt ctgggtgcgg cgcgtatcat tgaactggta aataaaattg gcctggatcg
    25681 tgggccgctg gcctgtgcga cggtgggcat gatgcaaatc catcccaatt cgcgcaatgt
    25741 catccccggt cgtgtgttcc tgaccgtcga tttccgccac cctgatgatg ccgttctggc
    25801 cgatatggat gccgtccttc gcaaaggggt ggaagacatt aaatccggca tcggtcttga
    25861 atgcgaattt gaacagattt tctattacgc acctgtgccg tttgacccgt cctgtgtgga
    25921 tgcggtgcgt aagggtgcgg aacgcggtgg ttataaggca cgcgaaattg tttcgggtgc
    25981 ggggcatgat gcctgctacc ttgcccaggt cacgcctacc gcgatgatct ttatcccctg
    26041 tgtggatggc atttctcata acgagatcga ggaagtccat aagcactggt cagatgcggg
    26101 cgggcaggtg ctgcttgatg ccgttctggc gaaggcggat gaaaaaccgg gtgagcaggc
    26161 cgcttaattc gcaccacagg ttcgcaattt tattgaaaca cccctccctc gcgggctgcc
    26221 ttttgggcgg cccgtatttt tttgatggcg gtgccgggct ggttttattc cggggtgggc
    26281 gctggcgcag tctgcgcgtc tggtttgggc aaatgggcct gcgtcatggt ggcaagttgg
    26341 ccgttttgct caagctgttc gataaacgca tccagttcgg gcacaaggtc ccggcagggg
    26401 gattttttgg aaaacatgaa catgacggga ttttgcatca gcggtttttc taccatgcga
    26461 atttgatcgc caatattatc gttgatgata ttggccatgc cgtcaaaccg gcccagcatc
    26521 acataatcca cgcgattgct ggtaagcaga tcaaggatgc ggttgcccgt cggggaaaag
    26581 atgatgtcga ggtagtcctc ggcgtaatga tcgagaaaat cgccataact gccaccctga
    26641 ggccgtgcac cccggcggtc aataaggtcg cggacatgat ccaccagaaa gggccgcttg
    26701 gcgctttgaa agaccatgat atcgtcggat gcatagggct gcgaatatgt aaattcacgg
    26761 tcccgttctt cggtgaaata ggcgccggcc atggcatcaa tctcgccgct tgccagcatc
    26821 aacatgcccc ggttccacgg aatatccaga tttacatcca gttccagccc gcgtgatgat
    26881 gtaaattccc gtaaaatatc gaccgataca ccatgggcaa cgccgttttt gtcctgatag
    26941 gaaattggct cccatccggc ggcacccgtt atatgcagct tcgtgcatgt tgccgatgcg
    27001 ttggcacttt caaatggcga cgaaatggaa gctttgttgg ccaaactgcc gttcaggccg
    27061 ggttgcgttt gcaatacgcg cgcattgctg gtggacgaaa ccgacagacc accggcaagc
    27121 aaaaccagaa ctgcaacgcc ccatttcttt cccatattac cgcctgcccg gaatgaccca
    27181 ttactgatct aaattggcgt aaaggctgga aattcaacta ttctttagaa tggctatcaa
    27241 ggcggcatat gtgctgttca gcgatagcgg gctcaattca acccgatgcc tttcaaaata
    27301 atttgcacga cattctcctt tgcttttgca aactgctggt cactcaatgc ctggttgccg
    27361 ttgaaaattt caatctggct agaaaagtcg gcatagtgct gggtggtggc gaagatcatg
    27421 tacatcaggc tgtagggttc gacattgtcc attttgcctt ccgcgatcca gcggcggatg
    27481 atgcgcaccc ggccatcgag ccagtccttg accgtggtgg aaatataatc ggacgagaat
    27541 ttagccccac ggacgatttc atgtgcccag acgcgcgagc catagggggt gctgcgcgac
    27601 aggtccattt tggcctcgat atagccgcgc aggatggtgg cggggtcggt ggtgttttca
    27661 aatgtcatgg ctgcttccag ccattgtgag cagacatttt cgatcacgcg tcgataaagt
    27721 gcctctttgg tggcgaagta ataatggaca ttggccttgg gaacattggc aacctcggca
    27781 atgcgggcgg tggtggcccc cttgaaaccg taatcggcga aaacccgttc ggcagcggca
    27841 agaatctgga cttcgttttc ctggcggatg gcggccttgt gcgcgccgtt ggccggcttt
    27901 gcagttgtgg tcataacccc tgtcccgtct ttctatgtat ttatcttgac cgtttggtca
    27961 ggttaaaata atctctgttt taacggctaa aaagcaagct gaaatttgcc aggcacttta
    28021 ccattggcgg ccaaaggcgc aagagcgtca gggcaggtcg gtgatcaatc tgcccggcag
    28081 ataataataa atacagggat cgcttcgatg tcatgctcat acgggtttgt tgtgcgaaat
    28141 cggtactgac agctacagtc attgtgctgt agtttttcat gtccggatcg cagggccacg
    28201 ccatgtgcga cgtgattctg tttccggttg gcagatgatt gtaattgttt gccaatttgc
    28261 ggatatgcca tgatcgacga atcatccggg gcctgcgccc tggaaaagcc aaaccgggtt
    28321 cgggagacct gataaaaatg actgccgcca catcatacaa ccgccccaat gatctgtctg
    28381 ctttctggat gccgtttacg gccaatcgcc agttcaagca gacgccgcgc atgctggttt
    28441 ctgccgaagg catgtattac actaccgatg ataatcgcca gatcctggac gggacggcgg
    28501 ggctttggtg ctgtaatgcc gggcacaagc gcgcgaaaat caacgaagcc gtccgcgccc
    28561 agcttgaaga aatggattat gcgccggcct tccagatggg ccatcccaag gcgtttgaac
    28621 tggcgacccg cctggcacaa ttgatgcccg gcgacctgaa ccatgttttc tataccaata
    28681 gcgggtcgga atcggttgaa accgccctta aaattgccat tgcctatcat cgtgcgcgcg
    28741 gtgatggcca gcggacccgc ctgatcgggc gtgagcgcgg ctatcatggc gtgaattttg
    28801 gcggcatttc ggtgggcggt attccgacca accgtaaaac atttggcacc atgctgggtg
    28861 gggttgacca tatccgccac acgcacctgc ctgaagaaaa caaatttgtg cgcggcgagc
    28921 cggaaaatgg cgcgtggctg gctgatgatc tggagcgttt gtgcgccctg catgacccct
    28981 caaccattgc cgctgtgatt gtcgagccgg ttgcagggtc gaccggcgtt ctgatcccgc
    29041 cgcagggtta tttgcagcgg ctgcgcgaaa tttgcaccaa acatggcatt ctgctgattt
    29101 ttgatgaagt cat
//
