LOCUS       NZ_CP024199            20840 bp    DNA     circular CON 03-MAY-2024
DEFINITION  Thalassospira marina strain CSC3H3 chromosome, complete genome.
ACCESSION   NZ_CP024199
VERSION     NZ_CP024199.1
KEYWORDS    RefSeq.
SOURCE      Thalassospira marina
  ORGANISM  Thalassospira marina
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
            Thalassospiraceae; Thalassospira.
REFERENCE   1  (bases 1 to 4530245)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Biodiversity and function of Thalassospira species in the
            particle-attached aromatic-hydrocarbon-degrading consortia from the
            surface seawater of the China South Sea
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4530245)
  AUTHORS   Dong,C., Liu,R. and Shao,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2017) State Oceanic Administration, The Third
            Institute, Room 329, Daxue Road 184, Xiamen, Fujian 361005, P.R.
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SMRT Analysis v. 2.3
            Genome Coverage                   :: 300
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002844375.1-RS_2024_05_03
            Annotation Date                   :: 05/03/2024 04:06:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,760
            CDSs (total)                      :: 4,670
            Genes (coding)                    :: 4,656
            CDSs (with protein)               :: 4,656
            Genes (RNA)                       :: 90
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 14
            CDSs (without protein)            :: 14
            Pseudo Genes (ambiguous residues) :: 0 of 14
            Pseudo Genes (frameshifted)       :: 2 of 14
            Pseudo Genes (incomplete)         :: 13 of 14
            Pseudo Genes (internal stop)      :: 4 of 14
            Pseudo Genes (multiple problems)  :: 4 of 14
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:03:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1394821
            Orig. end                         :: 1415661
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP024199.1.
            Bacteria and source DNA available from Dr. Zongze Shao; The Third
            Institute of State Oceanic Administration, Daxue Road 184#, Xiamen,
            Fujian, 3610015, China, Tel: 86-592-2195321.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20840
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20840
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20840
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10840](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10840
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    63..76
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    193..208
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    complement(409..422)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            complement(549..2699)
                     /locus_tag="CSC3H3_RS06315"
                     /old_locus_tag="CSC3H3_06310"
     CDS             complement(549..2699)
                     /EC_number="2.7.4.1"
                     /GO_component="GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007090860.1"
                     /locus_tag="CSC3H3_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06310"
                     /product="RNA degradosome polyphosphate kinase"
                     /protein_id="WP_101269488.1"
                     /transl_table=11
                     /translation="MKHAAAIQSSAITTDSEKRFINRELSWLAFNGRVLEEAQNQNHPL
                     LERLRFLSISASNLDEFYMVRVAGLVGQVRAGMTNISQDGLSPSEQLRAITYDANQLLQ
                     DQQRIWQQLRADMHHLGISVIEPDDLTQTDRKWLDGYFMREIFPTLTPLAIDPSHPFPF
                     IPNLGFAIVMQLFDPSDGHNMRGLIPMPPKIGRFLRLPGRTERYLPLEHAVLMYLDKLF
                     PGFDLIEHGLFRVIRDSDVEIEEEAEDLVRVFKTALKRRRRGSIIRLKVNASIPEDLLN
                     FVIDELNVAPEQVVKVDGLLGVVDVKQLIDSDLHHDLLFPPYAARYPERVRDFGGDCFA
                     AISKKDLVVHHPFEDFDVVVQFLLQAARDPDVVAIKQTLYRTSENSPIVKALIAAAEAG
                     KSVTAMVELKARFDEEANLRWAADLERAGCQVVYGFLEWKTHAKISLVVRRETHGLRTY
                     CHFGTGNYHPITAKFYTDISFFSCDPALGRDAGSIFNFMTGYATPRSLEKIAIAPHTLR
                     PSLVANIEKEIENAEAGKPCGVWAKMNSLVDPVVIDALYRASQAGVPVDLVVRGICCLR
                     PGVPGLSENIRVKSIVGRFLEHSRIVVFANGAKLPSRKAKAFISSADWMPRNLNRRVEC
                     LVPIENPTCHRQIIEQIMIANLKDTAQSWYLQPDGSYERCEAGKDAFSAHDYFMTNPSL
                     SGRGSALDEDSVSSVPVLVLDE"
     gene            2987..3565
                     /locus_tag="CSC3H3_RS06320"
                     /old_locus_tag="CSC3H3_06315"
     CDS             2987..3565
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007090861.1"
                     /locus_tag="CSC3H3_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06315"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_101286128.1"
                     /transl_table=11
                     /translation="MKTLLLLRHAKSSWADPGRADHDRELNPRGEKAAPVMGRFLMREG
                     LMPDLVWCSTAARAVQTLGLLGRQFAGDDQVIYAQDLYMASETALLKCLQQTHAEADRV
                     MMVGHNPGMESFALALTGIDENGHRPDMERKFPTCALCQFSFDVADWSAVKWGAGRLER
                     FIKVKNLQGDARPTNDDSDESSSPDSANT"
     gene            3773..5560
                     /gene="aspS"
                     /locus_tag="CSC3H3_RS06325"
                     /old_locus_tag="CSC3H3_06320"
     CDS             3773..5560
                     /EC_number="6.1.1.12"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /gene="aspS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008891273.1"
                     /locus_tag="CSC3H3_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06320"
                     /product="aspartate--tRNA ligase"
                     /protein_id="WP_101284314.1"
                     /transl_table=11
                     /translation="MHPYRSHNCNALRVSDADAQVRLSGWIHRKRDHGNLLFVDLRDHY
                     GITQVVIDISSPLFELLDKARAESVITVDGKVVKRTAETINPNLPTGEIEVYASNIEVQ
                     SSADVLPMPVFGDVEYGEEVRLRHRYLDLRRESVHKNIVLRSQVISAMRQKMTAQGFLE
                     IQTPILTASSPEGARDFLVPSRTHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRD
                     EDARADRSPGEFYQLDFEMAFATQDDVFAAIEPVLHEIFVEFGGGREVTDFPFPRIPFD
                     ESMAKYGSDKPDLRNPLVISDVTEAFRGSNFGIFASNIEKGSVVRAIPAPGAANRPRSF
                     FDKLNAWAREEGAAGLGYIVYDENGEAKGPIAKNLDAERIASIKETTGVANGDAVFFAC
                     DKPLPAAKFAGKSREKICDDLALREEGKFKFCWIVDFPMFEEDDDGKIEFSHNPFSMPQ
                     GGLDALENMNPLDIKAWQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYGKEVVEDRF
                     GGMLNAFKFGAPPHGGSAPGVDRIVMLLADEPNIREVIAFPLNQQAQDLMMNAPSVVED
                     RQLKELHLRVQLPPKAKKD"
     gene            5716..6834
                     /locus_tag="CSC3H3_RS06330"
                     /old_locus_tag="CSC3H3_06325"
     CDS             5716..6834
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CSC3H3_06325"
                     /product="hypothetical protein"
                     /protein_id="WP_101284315.1"
                     /transl_table=11
                     /translation="MKRFLIAAAPLFLSACGGSGDDTTLSKLADDLISYVTTGRTVAEN
                     QRALVAGQGCGTDASLFGNGDCKVGSGAAMGFVDRDGAGATNPLSGARSTTIYAVNTPV
                     EDWSKPGSARLHPYQNSADIMIVAVPPAASQLDQRAIAAQASAEPADMAAQDNAQSMAV
                     DDAPKAEMAALPGDDASTAMETTEMDAAKEDASSQPGGLDAATAATAKTTSKDVRPPAP
                     AKLESSDVRHKAMLPPAPAGAGAGAVTGAKAPANASLKGDAAGPDGQKQASGKDALAGK
                     QVSAQQSAPGAPANGKYVVLGSFTSHKRAQMALNQYAQYHPQLIPATVEGTPYLRIAVG
                     PMDMSRANNLRLVTAKNGVKDSWIVDIVGSGE"
     gene            6837..7679
                     /locus_tag="CSC3H3_RS06335"
                     /old_locus_tag="CSC3H3_06330"
     CDS             6837..7679
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007090864.1"
                     /locus_tag="CSC3H3_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06330"
                     /product="DUF1849 family protein"
                     /protein_id="WP_245881305.1"
                     /transl_table=11
                     /translation="MPNIMRNAAGRYATIAAAVVLGAALGGCSAQAGPSPAANGLVSHV
                     AEYRLRLISTSANSSVIAARGAFGFRFEKVCDGWISELRNSLILQGPQGSAINSSYSMT
                     QWEDFAAKHYRFRVRDFQDGYLTDEVNGNAERQDDKVVVHYEKPVDVTEELPVDTLFPT
                     QHSIKLLQHAIDGDVFASDRVFDGGGDTPTYQISAVVSGAMDADNKARDENHIADKPFH
                     RISMAFFPIDSDDDRPAYEMSIDYGKNGVAQGLVQNYGDFKLQGDLIRVRELPAPQCD"
     gene            complement(7819..8136)
                     /locus_tag="CSC3H3_RS06340"
                     /old_locus_tag="CSC3H3_06335"
     CDS             complement(7819..8136)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014249481.1"
                     /locus_tag="CSC3H3_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06335"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_101269498.1"
                     /transl_table=11
                     /translation="MEIKELEQQAERASGLLKAMSNQSRLMILCQLHNGERSVGELERI
                     IGLSQSALSQHLARLRRDQLVKTRREAQTIYYSLHGDEAIRVIKTLYELYCIDTEESDV
                     A"
     misc_feature    complement(8277..8291)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.8"
                     /tool="antismash"
     gene            8612..9541
                     /locus_tag="CSC3H3_RS06345"
                     /old_locus_tag="CSC3H3_06340"
     CDS             8612..9541
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014188037.1"
                     /locus_tag="CSC3H3_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06340"
                     /product="histone deacetylase family protein"
                     /protein_id="WP_101286129.1"
                     /transl_table=11
                     /translation="MATLFVTHRACIEHDPGPGHPEQPDRLRVIQRVLEAEEFMFLHRE
                     EATRADIDLIKKVHDPAYVDRIFAAIPAKGEISLDGDTYISPASGEAALRAAGGACVAV
                     DAVMQGHERNAFVGVRPPGHHAEYERAMGFCLFNNAAVAAHYAREKYGIKRVAVMDFDV
                     HHGNGTQDLFYHDPDLFYCSTHQWPLYPGTGDPMDRGCANNILNVALSAGAATAELQTA
                     FQDYVIPGLTGFAPELLIISAGFDAHRNDPLAGLSLVESDFTWMTEQLLAVAAQCCENR
                     VVSILEGGYDLPSLASSVLAHVRALMMG"
     gene            9666..9923
                     /locus_tag="CSC3H3_RS06350"
                     /old_locus_tag="CSC3H3_06345"
     CDS             9666..9923
                     /EC_number="3.1.11.6"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008891279.1"
                     /locus_tag="CSC3H3_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06345"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_101269502.1"
                     /transl_table=11
                     /translation="MSDANPVIPEDIAKLSFEEALGQLENLVRQLEQGQVGLDDAIASY
                     ERGAALKRHCADKLRAAEERIEKITLGADGRPSATATEIE"
     gene            10001..10840
                     /locus_tag="CSC3H3_RS06355"
                     /old_locus_tag="CSC3H3_06350"
     CDS             10001..10840
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008891280.1"
                     /locus_tag="CSC3H3_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06350"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_101286130.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.3e-59, bitscore:
                     198.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDKILPRPDGQIEERLFEAMRYSTMGEGKRLRPFLVMASSGLFK
                     VSRTSALRVAAAIEMVHTYSLIHDDLPAMDNDDLRRGKPSCHKQFDEATAILAGDALLT
                     QAFEVLADEETHPDPRVCTQLVRAMARAAGPYGMVGGQMIDLAGEGKSLSETQVTHLHL
                     LKTGRMFAFACEAGAILGKAPTSMRMGLRAYAHDMGLAFQIKDDLLDVEASSDDLGKTA
                     GKDAEQEKSTYVKLLGLEQAREQAQMLCDQAIHHLDAFDGEAEPLRAVARFVIDRKR"
     misc_feature    10041..10056
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.72"
                     /tool="antismash"
     gene            10867..11829
                     /locus_tag="CSC3H3_RS06360"
                     /old_locus_tag="CSC3H3_06355"
     CDS             10867..11829
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008891281.1"
                     /locus_tag="CSC3H3_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06355"
                     /product="hypothetical protein"
                     /protein_id="WP_101284316.1"
                     /transl_table=11
                     /translation="MPDTQDKPAYSAGFRDRIFDKDPFPLALWYPAVGEETPVRHMGVA
                     SKVARNAEFALGGPFPLVIISHGSEGHRFVHFWLAEHLARRGYIVAAPQHEGDNYIDAG
                     DARSLTIIERRPFEVSQALDLILAREDIAPHIDQGRITALGHSAGGATVLKLAGWQFDA
                     GEWQRYCEINHESDRVICEFVPGDHDLNRLAGSHGAPIVPARDGRISAIIAIAPAFGVA
                     ATPAGFEGVDIPMLVIEADTDEVLLHDVNAARFRELLRGRARFVRVKGAGHYSFLPPCT
                     EYIAQNFPHLCRDFGRERHQIHDSVKQLVAHFLDRVHAG"
     gene            11961..13877
                     /gene="dxs"
                     /locus_tag="CSC3H3_RS06365"
                     /old_locus_tag="CSC3H3_06360"
     CDS             11961..13877
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012977223.1"
                     /locus_tag="CSC3H3_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06360"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_101284317.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 9.5e-121,
                     bitscore: 400.0, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.1e-05, bitscore:
                     21.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSKTPLLDTVTIPSDLRKLQPAQLRQLADELRQETIDAVSVTG
                     GHLGAGLGVVELTVAIHYLFDTPHDRVIWDVGHQCYPHKILTGRRDRIRTLRQGGGLSG
                     FTKRSESEYDPFGAGHSSTSISAGLGMAVANQLSDDKRKNVIAVIGDGAMSAGMAYEAM
                     NNAAATDQRLIVILNDNDMSIAPPVGSMSGYLSRLISGKSYQGLRNAAKGLTKHLPRQI
                     EEAARKIEEYTRGMMTGGTLFEEMGFFYVGPIDGHNLDHLLPVLKNVRDADLDGPILIH
                     AVTQKGKGYAPAEHAADKYHGVAKFDVVTGKQAKPTPNAPSYTKVYGETLVKLGQKDEK
                     VTAITAAMPSGTGVNLFADAFPERSFDVGIAEQHAVTFAAGMACEGYKPFCTIYSTFLQ
                     RGYDQLVHDVVVQNLPVRFALDRAGLVGADGATHAGAYDLAYLGCLPNIVLMAPADEAE
                     LVHMTTTAWAIDDRPSAFRYPRGEGVGVELPAEGQVLEIGKGRVLREGSKIAILSYGTR
                     LAESLSAAEDLAARGLSTTVADARFAKPLDGELIEKLARNHEVLITIEEGSIGGFGALV
                     LQHMAGHGLLDLGLKVRTMTLPDTLLDHDKPEKQYAEAGLDAAAIVSTALAALGLDESK
                     ARA"
     gene            complement(13997..16219)
                     /locus_tag="CSC3H3_RS06370"
                     /old_locus_tag="CSC3H3_06365"
     CDS             complement(13997..16219)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1051:
                     TonB-dependent siderophore receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /locus_tag="CSC3H3_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06365"
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="WP_157831850.1"
                     /transl_table=11
                     /translation="MSLSAKCRSPFGLALLASASLLALSSVSVSAQETKTTQKSDDQTI
                     ELEPITIEGQAAQEAGDPTPPVYAGGQVATGGRAGILGNKDTLDTAINTSSYTEKLIKD
                     QQADTIADVVDNDPGVVTSYSYGGSGDRYMIRGFVLDGDDVSLDGLYGTAPRQLVDVSM
                     YDRVEVTKGASGFINGMSPGGSGIGGAINLVPKRATDTPITSLTTTYGMDSEVGTHLDV
                     GRRFGKDNQFGIRANLKYSDGETAIDDEERETIAGALSFDYRGDDTRITIDSGHNEKNT
                     DHGRTSITLNSALTAIPDAPSASHNFNADGTWADLQDDFVQGRVEHDFSENVMGYAAIG
                     TRHMEESGIYSTSRIDGTDGTMSYSSSYIVREDTTNSAMGGARVKFDTLDISHELNVGA
                     SGMWSKSHQAWAFASGFARNSGNIYGETPSSYPALGAATGDLNDPGLRNTNDLTSYFLA
                     DTLSFLDDRVHFTAGVRRQSVTTRQFDLTSGARTINYSADEYTPMFGVVGNVTEQVSVY
                     ANYMESLSPGETAPSAGSDPTLTNPSEQLAPYTSEQYEIGVKADYGTIGGSIALFQIEK
                     PSAYKNASNTFAADGEQRNRGLELQIFGEPVEGTRILGGVTLLDAQLTDTQNGTNNGNS
                     PIAVPDYVAKLGVEYDLPFLHGATVNARVIHTASQYADAANTLEIPSWTRLDLGARYET
                     ELGNYPVTMRANVENVTNNDYWASANGGYLTMGAPLTAKLSLTVDF"
     misc_feature    16274..16287
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 19.95"
                     /tool="antismash"
     misc_feature    16281..16296
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.69"
                     /tool="antismash"
     misc_feature    complement(16281..16299)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.82"
                     /tool="antismash"
     misc_feature    16297..16312
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.78"
                     /tool="antismash"
     misc_feature    complement(16300..16315)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.32"
                     /tool="antismash"
     misc_feature    16303..16318
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.42"
                     /tool="antismash"
     misc_feature    complement(16305..16319)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.0"
                     /tool="antismash"
     misc_feature    complement(16306..16321)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.74"
                     /tool="antismash"
     misc_feature    16501..16519
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 28.21"
                     /tool="antismash"
     misc_feature    16502..16518
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 24.96"
                     /tool="antismash"
     gene            complement(16530..17312)
                     /locus_tag="CSC3H3_RS06375"
                     /old_locus_tag="CSC3H3_06370"
     CDS             complement(16530..17312)
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-172). E-value: 1.8e-10. Score:
                     32.9. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS06375_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009541133.1"
                     /locus_tag="CSC3H3_RS06375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06370"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_101284319.1"
                     /sec_met_domain="adh_short (E-value: 1e-31, bitscore:
                     108.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTHHPRVAFVTGGAQGLGLGISRHLLDAGWKVMMFDLDEEAGR
                     EAMDALDEDLREKCLFFAGDVASEKDIAIAVQRTIDRFGRIDGLVNNAGIANPHNGSFE
                     HLDWDDWQRVINVNLGGVFLAAKHATQHLRKSRGAIVNISSTRAFQSEADSEAYAATKG
                     GIVALTHAMAVSLAGAVRVNAIAPGWIEVGDWKKSSRRTTPAHSEQDKNQHPAGRVGIP
                     ADIANAVAFLLDGEKSGFITGETLRIDGGMTHKMIYQD"
     aSDomain        complement(16797..17288)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS06375_PKS_KR.1"
                     /evalue="1.80E-10"
                     /label="CSC3H3_RS06375_PKS_KR.1"
                     /locus_tag="CSC3H3_RS06375"
                     /protein_end="172"
                     /protein_start="8"
                     /score="32.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAFVTGGAQGLGLGISRHLLDAGWKVMMFDLDEEAGREAMDALDE
                     DLREKCLFFAGDVASEKDIAIAVQRTIDRFGRIDGLVNNAGIANPHNGSFEHLDWDDWQ
                     RVINVNLGGVFLAAKHATQHLRKSRGAIVNISSTRAFQSEADSEAYAATKGGIVALTHA
                     M"
     CDS_motif       complement(17220..17279)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS06375_0001"
                     /evalue="1.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="CSC3H3_RS06375"
                     /protein_end="31"
                     /protein_start="11"
                     /score="11.2"
                     /tool="antismash"
                     /translation="VTGGAQGLGLGISRHLLDAG"
     gene            complement(17388..18338)
                     /locus_tag="CSC3H3_RS06380"
                     /old_locus_tag="CSC3H3_06375"
     CDS             complement(17388..18338)
                     /NRPS_PKS="Domain: PKS_ER (16-313). E-value: 1.4e-12.
                     Score: 39.3. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS06380_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="CSC3H3_RS06380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06375"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_101284320.1"
                     /transl_table=11
                     /translation="MNNSALWYRQFGEPVDVLSLKSAPLAPLEQGLVRVEMMAAPINPS
                     DLIPITGAYRHRISPPLVAGYEGLGTIAEIPTGSTCPFGLGQRVLPLRANGTWQNFVDA
                     DPAWMVPVPDDIDDEIALRGYINPLAAWLMLDLWPVKDKNVVITAAGSSCAGLLMQWAL
                     AQGAASVCGIYRSPSRKAGITALGADAIDMASEAALTNAAGKADLVFDAVGGDLARHLL
                     AHMPAGSILVSYGLLSGQLFALPENAQARIQRFHIRDRLETVSAQKWQDWFTNLWPLLR
                     DATLPPIAVFDLADWKDAITYFNQPGRLEKPVLQF"
     aSDomain        complement(17400..18290)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS06380_PKS_ER.1"
                     /evalue="1.40E-12"
                     /label="CSC3H3_RS06380_PKS_ER.1"
                     /locus_tag="CSC3H3_RS06380"
                     /protein_end="313"
                     /protein_start="16"
                     /score="39.3"
                     /tool="antismash"
                     /translation="VLSLKSAPLAPLEQGLVRVEMMAAPINPSDLIPITGAYRHRISPP
                     LVAGYEGLGTIAEIPTGSTCPFGLGQRVLPLRANGTWQNFVDADPAWMVPVPDDIDDEI
                     ALRGYINPLAAWLMLDLWPVKDKNVVITAAGSSCAGLLMQWALAQGAASVCGIYRSPSR
                     KAGITALGADAIDMASEAALTNAAGKADLVFDAVGGDLARHLLAHMPAGSILVSYGLLS
                     GQLFALPENAQARIQRFHIRDRLETVSAQKWQDWFTNLWPLLRDATLPPIAVFDLADWK
                     DAITYFNQPGRLEKPV"
     gene            complement(18473..19459)
                     /locus_tag="CSC3H3_RS06385"
                     /old_locus_tag="CSC3H3_06380"
     CDS             complement(18473..19459)
                     /NRPS_PKS="Domain: PKS_ER (17-311). E-value: 1.8e-45.
                     Score: 147.4. Matches aSDomain:
                     nrpspksdomains_CSC3H3_RS06385_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014249170.1"
                     /locus_tag="CSC3H3_RS06385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CSC3H3_06380"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_245881306.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-10, bitscore: 39.3,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.1e-22, bitscore:
                     77.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSLTARQVMIDEHGPAKNMAVKTIPLAEPGPNDVRVRQTAIGFN
                     FIDVYQRSGAYRLSLPSPIGHEAAGVIEAVGSDVTDLKVGMRVAYMNAGLGAYTDMRNV
                     SADKLVPLPDNVSDEQAAATIFKGMTAQYLLKHTCPVQPGDMVIVHAAAGGVGQILSGW
                     AKALGAFVVGTAGSDEKCAIARAAGCDIAINYHSENWVEKLLEATEGRKARVVYDSVGK
                     HTFLHSLDLTQPFGMVVLYGAASGPAPEIAPEILNKKGCLFLTRPSVFPHNADPERFRA
                     NAADLFDAIGRGFVKVQIGARFALEDAPAAHELAEGRSSSGAILLVP"
     aSDomain        complement(18527..19408)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CSC3H3_RS06385_PKS_ER.1"
                     /evalue="1.80E-45"
                     /label="CSC3H3_RS06385_PKS_ER.1"
                     /locus_tag="CSC3H3_RS06385"
                     /protein_end="311"
                     /protein_start="17"
                     /score="147.4"
                     /tool="antismash"
                     /translation="KNMAVKTIPLAEPGPNDVRVRQTAIGFNFIDVYQRSGAYRLSLPS
                     PIGHEAAGVIEAVGSDVTDLKVGMRVAYMNAGLGAYTDMRNVSADKLVPLPDNVSDEQA
                     AATIFKGMTAQYLLKHTCPVQPGDMVIVHAAAGGVGQILSGWAKALGAFVVGTAGSDEK
                     CAIARAAGCDIAINYHSENWVEKLLEATEGRKARVVYDSVGKHTFLHSLDLTQPFGMVV
                     LYGAASGPAPEIAPEILNKKGCLFLTRPSVFPHNADPERFRANAADLFDAIGRGFVKVQ
                     IGARFALEDAPAA"
     CDS_motif       complement(18983..19030)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS06385_0002"
                     /evalue="5.90E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="CSC3H3_RS06385"
                     /protein_end="159"
                     /protein_start="143"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GDMVIVHAAAGGVGQI"
     CDS_motif       complement(19232..19270)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CSC3H3_RS06385_0001"
                     /evalue="3.50E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="CSC3H3_RS06385"
                     /protein_end="76"
                     /protein_start="63"
                     /score="10.4"
                     /tool="antismash"
                     /translation="IGHEAAGVIEAVG"
     gene            19493..19648
                     /locus_tag="CSC3H3_RS24385"
     CDS             19493..19648
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CSC3H3_RS24385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157831851.1"
                     /transl_table=11
                     /translation="MGVFDRIKRRRTTAIVDRRSKVKQLVGSGAAFACQKRLLLANHRE
                     IILCRL"
     misc_feature    19656..19669
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
ORIGIN
        1 tggctgccaa aaacggtatg caggcgcatg gcccccagcg gcaggctgac acgttcctgg
       61 atttgcccct gatcaagcag caccagttca agcgagccac ccccgatatc ccccatgatg
      121 ccggtggcat gcggatcacc cgaaataatg ccaaggcccg acaggcgggc ttcttcaagg
      181 ccatcaatga ttttgaccgt caggccggtt tcatcgaaaa cgcgacgaca gaaataatca
      241 ccatcgctgg cggcgcgcac ggcagcggtt gccagcacgt cgacgcgcga aattttcatg
      301 gccagcaaaa gggtggcaaa acggcgcagc gcaccgattg ccatttcaac cccttcggcg
      361 ttcagtttac ccgatccatc agggtcacgg cccagaccgc acatgacctt ttcgttgaaa
      421 atgggcgcag gggcgcgcgt ttgaccatca aaaacgacaa gccggacaga gttcgacccg
      481 acatcaatga tggcaatgcg cttggagacc ctttgatcgg taagcatatg gctgaaaata
      541 cctggttatt attcgtcgag aaccagcacc ggcacagaag acacgctgtc ttcatcaagg
      601 gcactgcccc ggcccgaaag ggacgggttg gtcatgaaat agtcgtgggc cgaaaacgca
      661 tccttgcccg cttcgcagcg ttcataggac ccgtcaggtt gcagatacca gctttgggcg
      721 gtgtccttca aattcgcaat catgatttgt tcgatgatct ggcgatggca agtgggattt
      781 tcaattggca ccagacattc gacacggcga ttgagattgc gcggcatcca gtcggccgat
      841 gaaatgaaag ccttggcctt gcgcgatggc agttttgcgc cattggcgaa aaccacgatg
      901 cgggaatgtt caaggaaacg cccgacaatc gatttgacgc gaatattttc cgacagaccc
      961 ggtacaccgg ggcgcaggca gcaaatacca cgcaccacca gatcaaccgg cacacccgcc
     1021 tgcgaggcgc gataaagggc atcgatcacc accggatcga ccaggctgtt cattttcgcc
     1081 cagacgccgc agggtttgcc agcctcggcg ttttcaattt ccttttcgat attggcaacc
     1141 aggctggggc gcagggtgtg cggggcaatg gcaatttttt caagcgagcg cggcgtggca
     1201 tagccggtca tgaagttgaa aatgctgcct gcatcgcggc ccagtgccgg gtcacacgaa
     1261 aagaaggaaa tgtcggtata gaatttggcc gtgatcgggt ggtagttgcc ggtgccaaaa
     1321 tggcaatagg tgcgtagccc gtgggtttcg cggcgcacaa ccagcgatat tttggcgtgc
     1381 gttttccatt caaggaagcc gtaaaccacc tggcagccag cacgttcaag gtcggcggcc
     1441 cagcgcaggt tggcttcttc gtcaaagcgt gccttaagct cgaccatcgc ggtaacggat
     1501 ttgcccgctt cggccgccgc aatcagcgcc ttgacgatgg ggctgttttc ggatgtgcga
     1561 taaagggtct gtttgatggc aaccacatcg gggtcgcgcg cggcctgcaa caggaactgc
     1621 accaccacgt cgaaatcctc gaacgggtga tgaacgacca ggtccttttt gctgattgcg
     1681 gcaaaacagt ccccgccaaa atcacgaacc cgttcggggt aacgcgcggc atagggcggg
     1741 aacagcaggt cgtgatgcag gtcggaatca ataagctgtt tgacgtccac cacacccaaa
     1801 aggccatcga ccttgacgac ctgttcgggg gcaacgttaa gttcatcgat cacgaaattc
     1861 aaaaggtctt cggggatcga tgcattgacc ttgaggcgaa tgatgctgcc acggcggcgg
     1921 cgcttcagcg cggttttaaa cacgcgcaca aggtcttcgg cttcttcttc gatttccacg
     1981 tccgaatcac ggatgacacg aaacaggcca tgttcgatca ggtcaaaccc ggggaacagc
     2041 ttatcaagat acatcaatac cgcatgttcg agcggcagat accgttcggt gcggcccggc
     2101 aggcgcagga agcggccaat tttcggcggc atcgggatca gcccgcgcat attgtgcccg
     2161 tctgaggggt caaacaactg catgacaatg gcaaatccca ggttcggaat gaacgggaag
     2221 ggatgtgacg ggtcaatggc aagcggcgtc agggtcggga aaatttcccg catgaaatag
     2281 ccatcaagcc atttgcggtc ggtctgggtc agatcatcgg gttcgataac ggaaatgccc
     2341 agatggtgca tatcggcgcg caattgctgc cagatgcgct gctgatcctg caaaagctgg
     2401 ttggcatcat aggtaatggc gcgaagctgt tcggacgggc ttaaaccatc ctggctaata
     2461 ttggtcatgc ctgcccggac ctggccaaca aggccggcca cacgcaccat gtaaaattcg
     2521 tccaggttgc tggccgaaat ggacaggaag cgcagacgtt ccagcaaggg gtgattctgg
     2581 ttttgggctt cttcgagaac gcggccatta aatgcgagcc acgacagttc gcgattgata
     2641 aagcgttttt ccgaatcagt ggtgattgca ctggattgaa ttgccgcagc gtgtttcacg
     2701 caaagcctcc tgccatgagc catatggtgt tggaattaaa acgccaccat ctctcttgcc
     2761 cgcgagtata cgataactgt ttgttaaact gcaatttgta acccggaaaa agcaattgcc
     2821 ccgatgacgg ccagatagat tcgacgtggc agaatagcca ataagatggt cctgaaatcc
     2881 tacaattata tgtcagtttt ttacgtggtg ccgatgccca ccttatggca tgtctgtggg
     2941 cgaaaacatt gatccatcgt aaatgggcaa agcgggcgag aaattcatga aaaccttgtt
     3001 gctgttgcgt catgccaaat ccagttgggc ggatccgggc cgggcggacc atgaccgcga
     3061 actcaacccg cgcggcgaaa aggccgcccc ggtgatgggg cgttttttaa tgcgcgaagg
     3121 gcttatgccc gatctggtgt ggtgttcaac cgccgcccgc gcggtgcaga cactgggtct
     3181 tttggggcgg cagtttgccg gggacgacca ggtgatttac gcccaggacc tttatatggc
     3241 gagcgaaaca gccctgctga aatgtttgca gcaaacccat gcagaagccg accgcgtgat
     3301 gatggtgggg cataatccgg gaatggaaag ctttgccctg gcattgaccg gaatcgatga
     3361 aaatggccat cgccccgata tggaacgcaa atttcccacc tgcgcactgt gccagttcag
     3421 ctttgatgtt gcggactggt cggccgtgaa atggggggca gggcggctgg aacgttttat
     3481 caaggtcaag aatttgcagg gtgatgcccg cccgaccaat gacgacagtg acgagagttc
     3541 gtcccctgat agcgccaata cttgacgcgg gcaggcgaga agcgttttat acggaaaaat
     3601 gagggtactg agcggtgcct gaaacaagga tgttttcgca aatgccgcct gggggatgcc
     3661 gatatggcac cgcaaggagg ggatttgcgc gttttttgtt tgacagcgcc ggtcagccat
     3721 gcacctttgc gcccaaatcg cggcccaaaa tataacgcaa cctggaaaga ccatgcatcc
     3781 ttatcgctca cataattgca atgcacttcg cgtttccgac gccgatgccc aagtccgcct
     3841 ttctggctgg atccaccgca aacgcgacca cggcaacctt ctgtttgtcg atttgcgcga
     3901 tcattatggt atcacccagg tcgtgatcga catttccagc ccgctgttcg aacttctgga
     3961 caaggcgcgt gcggaaagcg tgattacggt tgacggcaag gtcgtgaaac gtaccgccga
     4021 aaccatcaac ccgaacctgc cgaccggtga aatcgaagtt tatgcctcga acatcgaagt
     4081 gcagtcctcg gctgatgtgc tgccgatgcc ggtatttggt gatgtcgaat atggcgaaga
     4141 agttcgcctg cgtcaccgtt acctcgatct gcgtcgcgaa agcgttcaca aaaacatcgt
     4201 tctgcgttcg caggtcattt cggccatgcg ccagaaaatg acggcacagg gtttcctcga
     4261 aatccagacg ccgattctga ccgcgtcctc gccggaaggt gcacgtgact tcctcgtacc
     4321 ttcgcgtacc catccgggca aattttatgc cctgccgcag gccccccagc agttcaaaca
     4381 gttgctgatg gtttcggggt tcgaccgtta cttccagatc gcaccttgct tccgcgatga
     4441 agatgcacgc gctgaccgtt caccgggcga gttctatcag ctcgactttg aaatggcctt
     4501 tgccacccag gacgacgttt tcgctgcgat cgagccggtc ctgcacgaga ttttcgttga
     4561 atttggtggt ggtcgcgaag taaccgattt cccgttcccg cgtattccgt ttgatgaatc
     4621 gatggcgaaa tacggttcgg acaagcccga cctgcgtaac ccgctggtga tttcggatgt
     4681 gaccgaagca ttccgtggtt cgaatttcgg catctttgcc agcaacatcg aaaaaggttc
     4741 ggtggtccgt gcgatcccgg caccgggtgc cgccaaccgt ccgcgcagct tctttgacaa
     4801 gctcaacgcc tgggcccgtg aagaaggtgc ggctggtctg ggttacatcg tttatgatga
     4861 aaacggcgaa gccaaaggcc cgattgccaa gaacctggat gctgaacgca ttgcatcgat
     4921 caaggaaacc acgggtgttg ccaatggcga tgccgtgttc tttgcctgcg acaagccgct
     4981 tccggctgcc aaatttgcgg gcaagtcgcg tgaaaagatc tgtgatgacc tggccctgcg
     5041 cgaagaaggc aagttcaagt tctgctggat tgttgatttc ccgatgttcg aggaagatga
     5101 cgacggcaag atcgaattca gccacaaccc gttctcgatg ccgcagggtg gcctggacgc
     5161 gctggaaaac atgaacccgc ttgatatcaa ggcgtggcag tatgacatcg tttgtaacgg
     5221 tatcgagctg tcttcgggtg ccattcgtaa ccatcgcccg gacatcatgt acaaggcctt
     5281 tgaaattgcc ggttatggca aggaagtggt cgaagaccgc tttggtggca tgctgaacgc
     5341 attcaaattt ggcgcaccgc cgcacggtgg ttcggccccg ggtgttgacc gtatcgtcat
     5401 gctgctggcc gatgaaccga acattcgcga agtcattgcc ttcccgctga accagcaggc
     5461 acaggacctg atgatgaatg cgccgtcggt tgtcgaagac cgccagttaa aagaactgca
     5521 tttgcgtgtt cagttgccgc cgaaggcgaa aaaagactga tcacggcata tgccgctgac
     5581 tgaaatctcc aaaaagagcg attggcgatg ctgatcgctc ttttttgttg cgaatttgca
     5641 actggtgtta cccatatatt aaggtgctgt gcgtcagaat tggacaagga cgtattattc
     5701 gatgggagac gggcagtgaa acggtttctg atagcagcag cccccctgtt tctgagcgct
     5761 tgtggcgggt cgggggatga cacgacatta tccaaactgg ccgatgatct gatcagctat
     5821 gtcacgacgg ggcgcacggt tgccgaaaac cagcgtgcac ttgtcgccgg acagggctgt
     5881 ggtacggatg cgtcgctgtt tggcaatggc gattgcaagg tcggttccgg tgcggcaatg
     5941 ggatttgttg atcgcgacgg ggcgggggca acaaacccgc tttctggtgc gcgttccacc
     6001 accatttacg ccgttaatac tccggtcgag gattggagca aacccggcag cgcccgcctg
     6061 catccgtatc agaattcggc cgatatcatg attgtggcgg tcccgcccgc agcaagccag
     6121 cttgaccagc gtgctattgc cgcccaggca tcggcggaac ccgcagacat ggccgcgcag
     6181 gataacgcgc aaagcatggc tgtggatgac gcccccaagg cggaaatggc agctttgccg
     6241 ggggatgatg ccagcacggc aatggaaaca acggaaatgg acgcggccaa agaggatgca
     6301 tcgagccagc ccggtgggtt ggatgctgct actgccgcga ctgcgaaaac cacaagcaaa
     6361 gatgtccgcc caccggcacc ggccaaactg gaaagcagtg atgtgcgcca taaggccatg
     6421 ctgccacctg caccggccgg ggctggtgca ggggcggtaa ctggtgcaaa ggcaccagcg
     6481 aatgcgtccc tgaagggaga tgccgccggg ccggatggcc aaaagcaggc atcgggcaaa
     6541 gatgccctgg cgggcaagca ggtatcggca cagcaaagtg cgcccggtgc cccggcgaat
     6601 ggcaaatatg tggtgctggg cagttttacc agccacaaac gggcccagat ggcccttaat
     6661 caatatgcgc aatatcatcc gcaattgatt cctgcgacgg tagagggtac gccttatctt
     6721 agaattgcag taggtccaat ggatatgtcg cgtgcaaata atctgcgcct tgttacggcc
     6781 aaaaatggcg tcaaggattc gtggattgtg gatatcgtcg gcagcggaga gtagatttgc
     6841 caaacataat gcgaaatgcg gcaggccgtt atgcaacaat tgcggccgcg gtggtattgg
     6901 gggctgcgct gggtggttgt agcgcacagg caggaccttc accggcggca aatggtctgg
     6961 tttcgcatgt cgcggaatat cggctgcgcc tgatttcgac cagcgcgaac agttcggtta
     7021 ttgctgcgcg cggggcattt ggcttccggt ttgaaaaggt ctgtgacggc tggatttcgg
     7081 aattgcgcaa ttcgctgatt ttgcaggggc cgcagggaag tgcgatcaat tcatcctaca
     7141 gcatgaccca gtgggaagat ttcgcggcaa aacattaccg gttccgtgtg cgtgattttc
     7201 aggatggtta cctgaccgac gaggtaaacg gcaacgccga acgccaggat gacaaggttg
     7261 tcgtgcatta cgaaaaaccg gttgatgtca ccgaagaact gcctgttgat accctgtttc
     7321 cgacccagca ttccatcaaa ctgttgcagc atgccattga tggcgatgtc tttgccagcg
     7381 accgggtttt tgatggcggg ggcgatacac cgacctatca gatttcagcc gttgtctccg
     7441 gcgcgatgga tgcggacaat aaggcacgcg atgaaaacca tatcgcagac aagccgtttc
     7501 accgcatcag catggcgttt ttcccgattg atagcgacga tgaccgcccg gcttatgaaa
     7561 tgtcgattga ttacggcaaa aacggcgttg cccaggggct ggtgcaaaat tacggcgatt
     7621 tcaaattgca gggtgatctg atccgcgtgc gcgaattgcc tgcgccgcaa tgtgattaaa
     7681 gggctttaag ctgcccgtga tcgggtcggc atgtgcgacc cgccatatgg ggcaggcaga
     7741 tgatcaaata aaatggcctg ccgcatcccg atgacggcag gccatttctt ttatgcctgg
     7801 gatgcgcgca tgcccgtttt atgcgacgtc actttcctct gtgtcgatgc agtaaagctc
     7861 gtagagggtt ttgataacgc ggatggcttc atcaccgtgc agggaataat agattgtctg
     7921 tgcttcgcgc cgcgtcttga ccaactggtc ccgccgcaat ctggcaagat gctgggaaag
     7981 cgcagactgg ctgagcccga tgatccgttc aagttcaccc acggatcgct cgccattatg
     8041 caactggcac aggatcatta accggctctg gttgctcata gctttgagaa gcccactagc
     8101 ccgttcggcc tgttgttcta gttcttttat ttccatttgc ctcacttcat cccggattta
     8161 ctcccggttg cgaaagtgtg atagtttacc ccgctatcac agatgagact atgctcattt
     8221 tttcacaacc atggcgtttt atagacttat ggggataagc gcaatcccgt acgcgctgaa
     8281 aatgctgttc taaagtatcg tcttttacct gtttgagcag gtgccacctg cgaattggga
     8341 attttgacat tattttacgg ccatttccgg aaaactgtca aaattggact ttggtagagt
     8401 ttatttgcag ttgcgtgtgg tctatgccag ggcaggttac gccaaacggc gcaatgaagg
     8461 gttaaattgc aatcgtttct tcgttgcgtc aacccaagtg ttacgtaagg ttacaagaag
     8521 ccgcgcctgt ggcgacatgc cgcaggtgaa tgcccgtgtg atgtgcacat atgcaggggc
     8581 aggcacaaaa aacgggaggc agcagacaga aatggcaaca ttgtttgtca cgcatcgggc
     8641 ctgtatcgaa catgatccgg ggcctggcca ccccgaacag ccagaccgcc tgcgggtgat
     8701 ccagcgtgtg ctggaggccg aggaattcat gttcctgcat cgggaggagg ccacgcgcgc
     8761 cgatatcgac ctgatcaaaa aggtgcatga cccggcctat gtggaccgta tttttgccgc
     8821 catcccggcc aagggcgaaa tatcgcttga tggcgatacc tatatttcac cggcatcggg
     8881 cgaggcggcc ctgcgtgcgg cagggggcgc atgtgttgcc gtggatgcgg tgatgcaggg
     8941 ccacgaacgc aatgcctttg tcggggtgcg cccgcccggt caccatgccg aatatgaacg
     9001 cgcaatgggc ttttgcctgt ttaacaatgc ggcggtggca gcccattatg cgcgcgaaaa
     9061 atacggcatc aaacgggtgg cggtgatgga tttcgacgtg catcacggca atggcaccca
     9121 ggacctgttt tatcacgacc cggacctttt ttattgttcg acacatcaat ggccgcttta
     9181 ccccggcacg ggtgatccga tggatcgggg ctgcgcaaat aacattctta acgttgcgct
     9241 ttccgccggg gcggcaacgg ccgagctgca aacggccttt caggattatg tcattccggg
     9301 gctgacgggg tttgcaccgg agcttctgat aatctcggcg ggttttgatg cccatcgcaa
     9361 tgacccgctg gcgggattgt cgctggtgga aagcgatttt acctggatga ccgaacagct
     9421 tttggcagtg gcggcccaat gctgcgagaa ccgggtcgtg tcgattctgg aaggcgggta
     9481 tgatttgccg tcgctggcat cctcggtgct cgcacatgtg cgtgccctga tgatgggata
     9541 atatcgcgcc gatatcgcgt gtttgggtgc aattggcgtg ttacgcgaaa agaacggcag
     9601 ggctttgtgt tgccctgctg tttccttgcg cgtaaactcc gcccagccaa taaaaaggag
     9661 caaacatgtc ggacgcaaat cctgtaatac ccgaagatat cgccaaactg agctttgagg
     9721 aggccctggg ccagcttgaa aatctggtgc ggcagcttga acaggggcag gtgggccttg
     9781 atgacgcgat tgcatcctat gaacgtgggg ccgcgttaaa gcgtcattgc gctgacaaat
     9841 tgcgggctgc tgaagaacgc atcgaaaaga ttaccctggg tgccgatggc cgcccaagcg
     9901 caacagctac cgaaatcgaa taaccacatt caaggcggag tcccaggtga gctatgacct
     9961 gatttctgcg ctgggagagg cttctgccga tcttggcgac atgcttgaca agatcctgcc
    10021 ccgtcccgat ggacagattg aagaacgcct gtttgaagcc atgcggtatt ccaccatggg
    10081 cgaaggcaaa cggctgcgcc cgtttctggt gatggcatcg tccgggctgt ttaaagtttc
    10141 gcggacatcg gcattgcgcg tggccgccgc gattgaaatg gtccatacct attcgctgat
    10201 ccatgatgat ctgcctgcca tggataatga cgatttgcgt cgcggcaagc cgagctgcca
    10261 caagcagttt gacgaggcaa ccgccatact ggccggtgat gccctgctga cccaggcatt
    10321 tgaagtgctg gctgatgaag aaacccaccc tgatccgcgt gtctgcaccc agcttgtgcg
    10381 tgccatggcg cgcgcggcag gcccttacgg catggtgggc ggacagatga ttgatctggc
    10441 cggcgaaggg aaaagcctga gcgaaacaca ggtaacgcat ttgcacctgc tgaaaaccgg
    10501 gcgcatgttt gcctttgcct gcgaagccgg ggcgattttg ggcaaagccc ccaccagcat
    10561 gcgtatgggg cttcgggcct atgcccatga catgggcctt gccttccaga tcaaggatga
    10621 cctgctcgat gtggaagcca gcagcgatga tttgggcaaa accgcaggca aggatgccga
    10681 gcaggaaaaa tccacctatg taaagctttt gggcctggaa caggcgcgcg agcaggcaca
    10741 gatgctgtgt gatcaggcca ttcatcatct tgatgcgttt gatggcgagg cagaaccgct
    10801 tcgtgccgtt gcccgctttg tgattgatcg caaacgttaa gcaaagcgcg gattgaaggc
    10861 ggatcaatgc ccgatacaca ggataagccc gcctatagtg caggttttcg cgaccggatt
    10921 tttgacaagg atccgttccc gctggctttg tggtacccgg ctgtgggcga ggaaacaccc
    10981 gttcgccata tgggggttgc cagcaaggtc gcccgcaatg ccgaatttgc gctaggtggg
    11041 ccgtttccgc tggtgatcat ttcgcatggt tcggaagggc accgttttgt gcatttctgg
    11101 ctggcggaac atctggcgcg acgcggctat attgttgccg ccccccagca tgaaggcgac
    11161 aattacattg atgccggtga tgctcggtcg ctgaccatta tcgaacggcg cccgttcgag
    11221 gtaagccagg cgctggattt gattttggcg cgcgaggata tcgccccgca tatcgatcaa
    11281 ggccgcatta ccgcccttgg ccattcggct ggtggggcaa cggttttgaa actggcaggc
    11341 tggcagtttg atgccgggga atggcagcgt tattgcgaga tcaaccacga atctgatcgc
    11401 gtgatttgcg aatttgtacc tggcgaccat gatttgaacc gcctggctgg cagccacggt
    11461 gccccgattg taccggcacg cgatgggcgg atatcggcca tcattgccat tgcaccggcc
    11521 tttggtgtgg cggcaacccc ggcggggttt gaaggtgtgg atattcccat gctggtgatc
    11581 gaggcggata ctgatgaagt gttgctgcat gatgttaacg ctgcccgctt tcgcgaatta
    11641 ttgcgcggca gggcccgttt tgtgcgggta aagggggccg ggcattattc gtttttgccg
    11701 ccctgtacgg aatatattgc gcaaaatttt ccgcatttgt gccgggattt tggccgggaa
    11761 agacaccaga tccatgacag cgtaaagcag cttgttgcgc actttttgga tcgtgttcac
    11821 gcgggctgat tttggcgcaa tttcggggtc gctaattttg tgcaaccccg ctattttacg
    11881 ccccttgcaa tgggatcacc aaagcgtcac cctgttgtca tgaaattcaa cgctgagaga
    11941 acacaaaaat cgagttcggc atgaccacct ccaagacccc gctgcttgac actgttacga
    12001 tcccgtcaga cctgcgcaag ttgcagccag cccaattgcg ccagcttgcc gatgaattgc
    12061 gacaggaaac cattgatgcc gtctcggtca ccggggggca tctgggggct gggctgggtg
    12121 tggtcgaatt gaccgttgcc atccattacc tgtttgatac cccgcatgac cgggtgatct
    12181 gggatgtggg gcaccagtgc tatccgcata aaattctgac cgggcggcgc gaccgtattc
    12241 gcaccctgcg tcagggtggc ggtctttccg gttttaccaa acgttcggaa tccgaatatg
    12301 acccgtttgg tgcgggccat agctcaacct caatttcggc gggtctgggc atggcagttg
    12361 ccaaccagct atcggatgac aaacgcaaaa acgtgattgc cgtgatcggc gatggtgcga
    12421 tgagtgcggg tatggcctat gaagccatga acaatgctgc ggccaccgat cagcgcctga
    12481 ttgtgatttt gaacgacaat gacatgtcga ttgccccgcc ggtaggctcc atgtcggggt
    12541 atctgtcccg tctgatttcg ggcaaaagtt accagggctt gcgcaatgcg gccaagggcc
    12601 tgaccaaaca tctgccccgc cagatcgagg aagccgcccg caagattgaa gaatataccc
    12661 gtggcatgat gaccgggggc accctgtttg aagaaatggg tttcttctat gtcgggccga
    12721 ttgacgggca taatctggat catttgctgc cggttctgaa aaatgtacgc gatgccgacc
    12781 ttgatggtcc gatcctgatc cacgctgtga cgcagaaggg caagggctat gccccggcgg
    12841 aacatgcggc ggacaaatat catggcgttg ccaagtttga cgtggtgacg ggcaagcagg
    12901 ccaagccgac ccccaatgca ccatcctaca ctaaggttta cggtgaaacg ctggtcaagc
    12961 tgggccagaa ggatgaaaag gtaacggcga ttaccgctgc catgccgtca ggcacggggg
    13021 ttaacctgtt tgctgatgcg ttcccggaac gctcctttga tgtggggatt gccgaacagc
    13081 atgccgtaac ctttgctgcc ggtatggcat gcgaaggcta caaaccgttt tgcaccattt
    13141 attccacctt cctgcagcgc ggttatgacc agctggtgca tgatgtggtg gtccagaacc
    13201 tgccggtgcg tttcgcactg gaccgggccg gtctggtggg ggcggatggg gcaacccatg
    13261 ccggggccta tgacctggcc tatctgggat gtttgcccaa tatcgtgctg atggccccgg
    13321 cggatgaagc cgaactggtc catatgacca ccacggcctg ggccattgat gaccgcccca
    13381 gcgcgtttcg ttatccgcgc ggcgaaggtg tgggtgttga actgcctgcc gaaggccagg
    13441 ttctggaaat tggcaagggg cgcgttttgc gcgaaggcag caagattgcc attctgtctt
    13501 acggtacccg ccttgctgaa tccctttctg cggccgagga tctggctgca cgtggccttt
    13561 caaccacggt ggccgatgcc cgctttgcca agccgctgga tggcgagctg attgaaaagc
    13621 tggcacgcaa ccacgaagtg ctgattacga tcgaagaagg gtcgattggc ggctttggtg
    13681 cgctggtatt gcagcatatg gcagggcatg gcctgctgga tctgggcctg aaggttcgga
    13741 ccatgacttt gcctgatacg ctgcttgatc atgacaaacc cgaaaaacaa tatgccgaag
    13801 cagggcttga tgctgccgca attgtcagca ccgcactggc agcattgggc ctcgatgaaa
    13861 gcaaggcacg ggcctgattt taagttatcc catggcctga ttggccgttg gcaaacacct
    13921 atcgcgcaca taaaaacgcc acccggtttt tcgggtggcg ttttgttttt gggtgctgtg
    13981 cctgttggca gggtgatcag aaatcaaccg tcagcgaaag tttggccgtc agcggtgcgc
    14041 ccatggtcag atacccgcca ttggccgatg cccaataatc gttattggtg acgttttcga
    14101 cattggcccg catggtaacc ggataattgc caagttcggt ttcataacgt gcgccaaggt
    14161 caaggcgcgt ccaggacgga atttcaaggg tattggcggc atcggcatat tgtgatgccg
    14221 tgtggatgac gcgggcattg accgtcgccc cgtgaaggaa cggcaaatca tattccacgc
    14281 ccagttttgc aacatagtcg ggcacggcga tggggctgtt gccattgttg gtgccgtttt
    14341 gggtgtcggt cagctgggca tccagcaggg tgacgccgcc cagaatacgt gtgccttcaa
    14401 ccggctcgcc aaatatctga agttccagcc cacggttgcg ctgttcgcca tcggcggcaa
    14461 atgtgttgct ggcattttta taggccgacg gcttttcgat ctggaacagg gcgatgctgc
    14521 cgccaatggt gccgtaatcg gctttgacgc cgatttcata ttgttcggac gtgtaggggg
    14581 caagctgttc gctggggttg gtcagggtcg ggtccgaacc ggcagagggg gccgtttcac
    14641 ccggcgaaag tgattccatg taattggcat agacagagac ctgttcggtc acgtttccga
    14701 cgacaccaaa catcggcgtg tattcatcgg cgctgtaatt gatggtgcgc gcaccactgg
    14761 tcaggtcgaa ctgccgtgtg gtgacggact ggcgacgaac tccggcggta aaatgaacgc
    14821 ggtcatcaag gaagctaagc gtatcggcaa ggaaatagct ggtcaggtcg ttggtgttac
    14881 gcaggccggg atcgttcaga tcgccggtgg ctgcccccag tgccggatag gatgacggcg
    14941 tttcgccata gatattgccg ctgttccgag caaaaccgct ggcaaaggcc caagcctggt
    15001 ggcttttgct ccacatgccc gatgcgccaa cattaagctc gtgtgaaata tcgagtgtat
    15061 cgaatttcac ccgtgcgccg cccatggcac tgttggtggt atcctcacgc acgatatagg
    15121 agctgctgta gctcatggtg ccatcggtgc catcaatccg cgaggtggaa taaataccgg
    15181 attcttccat atggcgcgtg ccaatggcgg catagcccat cacattttcg ctgaaatcat
    15241 gttcaacgcg gccctggaca aaatcatcct gcaggtcggc ccaggtgcca tcggcgttaa
    15301 aattatggga tgcagacggg gcatcgggga tcgcagtcag tgcgctgttc agcgtgatcg
    15361 aggtgcggcc atgatcggtg tttttttcgt tatggccgct atcgatggtg atgcgggtgt
    15421 cgtcgccgcg atagtcaaat gacagggcac cagcgatggt ttcgcgttct tcatcatcaa
    15481 tcgctgtttc gccgtcgctg tatttcagat tggcgcggat gccaaactgg ttgtccttgc
    15541 caaaacggcg gcccacatca aggtgggtgc caacttcgct atccatgcca taggtcgtgg
    15601 tcaggctggt aattggcgtg tcagtggcgc gcttgggcac caggttaatg gccccgccaa
    15661 tgccgctgcc gcccggtgac atcccgttga taaagcccga tgcgcccttg gtgacttcga
    15721 cacgatcata catcgataca tcgacaagct ggcgcggtgc cgtgccatac aggccatcaa
    15781 gcgaaacatc atcgccatca agcacaaaac cgcggatcat gtaacggtcg cccgacccgc
    15841 catagctgta ggatgtgaca acgccggggt cattatcgac cacatcggca atggtatcgg
    15901 cctgctggtc cttgatcagt ttttcggtat aggacgatgt gttgattgcc gtatcaagcg
    15961 tatccttgtt ccccagaata ccggcacgcc cgccggtggc aacctggccg cccgcataga
    16021 cgggtggggt gggatcgccg gcttcctgcg ctgcctggcc ttcgatggtg atcggttcaa
    16081 gttcgatggt ctggtcatcg gacttctggg tggttttggt ttcctgtgca gaaacactga
    16141 ccgaagaaag tgcaagcaga cttgccgatg ccagcaaagc caacccgaac gggctgcggc
    16201 atttcgcaga aagtgacata tcgattcccc aagaattttg cgcagatccg tgatctgcaa
    16261 aactgccctc cgatatcatt attaataatc aatcgcaatg ataatgatca tgattatcaa
    16321 tagcgatata aaagttcagt tttgcaattt gccgtttcag caaaacaaaa cctgcgcgtg
    16381 taatatttgg gatttttcgg ggatgttgcg ccttatgcgg gtatttttcc cgtgcttatg
    16441 ccaaaaggct ggcaaaggca ttccttcgcc agtccgatgc tgaaactgcg aatttgaaat
    16501 attgcgaacg agtcgcagat atgcgggggt cagtcctgat agatcatttt atgggtcatg
    16561 ccgccatcaa tgcgcagcgt ctcgccggtg ataaagccgg acttttcccc atcaagcaaa
    16621 aaggcaaccg cattggcaat gtccgccggg atacccacac gcccggcggg gtgctggttt
    16681 ttatcctgtt cgctatgggc gggtgttgtg cgccgggatg attttttcca atcgccaacc
    16741 tcgatccagc ccggtgcaat ggcattaacg cgcaccgcgc ctgcaaggct gacagccatc
    16801 gcatgggtca gggcaacaat accgcctttg gtcgcggcat aggcttcgct atctgcttcg
    16861 gactgaaagg cgcgggtcga ggatatattc acaatcgccc cgcggctttt gcgcaaatgc
    16921 tgggtcgcat gtttggccgc cagaaacacc ccccccagat tgacattgat cacgcgctgc
    16981 cagtcatccc agtccagatg ttcaaatgac ccgttatggg gattggcgat accggcattg
    17041 ttaaccaacc cgtcaatgcg accaaagcgg tcaatggtgc gctgaacggc gatggcgata
    17101 tccttttcac tggcaacgtc accggcaaaa aacaggcact tttcgcgcaa gtcttcatca
    17161 agggcgtcca tcgcctcgcg cccggcttct tcatccagat cgaacatcat caccttccag
    17221 cccgcatcaa gaagatggcg actgatgcca agccccaggc cctgtgcgcc accggttaca
    17281 aaggcaacgc gggggtgatg tgtgtcggtc atgaagatgt cctttcaaat gtcgggcggg
    17341 caggaaggat cgaaaacagg caaagaaaat actgccacac catgaattca gaattgcagc
    17401 accggttttt ccaaacgccc cggctgattg aaataggtaa tggcatcttt ccagtctgcc
    17461 aggtcaaaaa cggcgatggg cggcagggtt gcgtcacgca gcagcggcca aaggtttgtg
    17521 aaccagtcct gccatttttg cgccgaaacg gtttcaagcc ggtcacggat atgaaaacgc
    17581 tgaatgcggg cctgggcatt ttccggcagg gcaaatagct gccccgataa caggccatag
    17641 gataccagga tgcttccggc gggcatgtgg gccagtaaat ggcgggcaag atcaccacca
    17701 acggcatcaa atacaagatc ggctttgccc gcagcgttgg taagtgcggc ttcgctggcc
    17761 atatcaatgg catcggcacc aagggcggta ataccggcct tgcgcgacgg gctgcgataa
    17821 ataccgcaca ccgatgccgc accctgtgcc agtgcccact gcatcagcaa cccggcgcag
    17881 gatgatcccg ctgccgtgat cacgacgttt ttgtccttca ccggccaaag atcaagcatc
    17941 agccaggcgg caagcgggtt gatatagccg cgcagggcaa tttcatcgtc aatgtcatcg
    18001 gggacaggca ccatccaggc cgggtccgca tcgacaaaat tttgccaggt gccattggcg
    18061 cgaagcggta atacacgttg ccccaggcca aaggggcagg tgctgccggt cgggatttcg
    18121 gcaatcgtgc ccagcccttc atacccggca acaagcggtg gggaaatacg gtggcgatag
    18181 gcgccggtaa tcgggatcag gtcagacggg ttaatgggtg ccgccatcat ttcgacccgg
    18241 accaacccct gttccagcgg ggccagtggt gcggatttaa gggatagaac atccaccggc
    18301 tcgccaaatt gccgatacca aagggccgaa ttattcatgt gaaattgcct gctgccagaa
    18361 gagaatgccg accttaatgc ctttggcaga taacagccag cccgatcccg tttttatgct
    18421 gcctttggcg taaaggggat cgggctggtg atggttcagg ttttaacagg cgtcagggaa
    18481 ccagcaggat cgccccgctg gaagaccggc cttcagccag ttcgtgggcg gccggggcgt
    18541 cttccagggc gaagcgcgca ccgatctgga ctttgacaaa gccacggcca attgcatcaa
    18601 acaggtcggc ggcattggcg cggaaacgtt cagggtcggc attatgcggg aaaaccgacg
    18661 gacgggttaa aaacaggcaa ccctttttat taaggatttc cggggcaatt tcgggtgccg
    18721 ggccggatgc cgcaccataa agcaccacca tgccaaacgg ttgcgtcagg tccagcgaat
    18781 gcaggaaggt gtgtttgcca accgaatcat aaaccacgcg ggctttgcgg ccctcggttg
    18841 cctccagcag tttttcaacc cagttttcgc tgtggtaatt aatggcaata tcgcagcctg
    18901 cggcgcgtgc aatggcgcat ttttcatccg atccggccgt gccaaccaca aatgcgccca
    18961 atgccttggc ccagcccgaa aggatctggc caacaccacc ggcagcggca tgcacaatta
    19021 ccatgtcgcc gggctgaacc gggcaggtat gtttcagcag atattgcgct gtcatgccct
    19081 tgaaaatcgt ggcggcggcc tgttcgtccg acacattgtc aggcaggggc accagcttgt
    19141 ccgcactgac attgcgcata tcggtatagg ccccaaggcc cgcattcata taggccaccc
    19201 gcatgccaac cttaaggtcg gtaacgtcgc tgccaacggc ttcaatcacg ccggcggctt
    19261 catgcccaat cgggctgggc agggaaagcc gataggcacc gctgcgctga tagacatcga
    19321 taaagttaaa accaatggca gtttgacgaa cgcggacgtc gttcgggccg ggttcggcca
    19381 ggggaatggt tttgacggcc atgtttttgg ccgggccatg ttcatcgatc atgacctgac
    19441 gggctgtaag cgaagacatt gttttgttct ccacagatag gatgtttccg taatgggagt
    19501 attcgacagg ataaaaagac gccggacaac agcaattgtt gaccggcgca gcaaggtgaa
    19561 gcaattggtc ggcagcgggg cggcttttgc atgtcaaaag cgcctgctgc tggcaaatca
    19621 ccgggagatc attttgtgcc gcctgtgaag gtatcggcat attcattgcg caattgggcc
    19681 ttttggacct tgcccatcgt gttgcgcggc agttcatcaa ttttccagat gcgtttgggc
    19741 accttgaatt tcgccagctt gtcctgggta cgtttgatca gttcctgttc atcaaacccg
    19801 gcggcatttg acgggacgat aaccgcggca accgcctcgc caaaatcggg gtgcggcagg
    19861 ccaaagacgg caacttcgcc aacttcgtca taatcaccga tgatttcttc gacttccttg
    19921 ggatagacgt taaagccacc tgaaatgatc aaatccttgt cgcggccaac gatggtgaca
    19981 tatccatcat cgcccagcgt tgcgaggtcg ccggtaataa agaacccatc ggcgcggaat
    20041 tcggatgcgg ttttttccgg catctgccag taacccttga acacattggg gccgcgaact
    20101 tccagaacgc caatttcgcc atgtggcagg atattgccat ccttgtcgca cacccgggct
    20161 tcaatgccag gcagggtcgg gccaacggca ccggggcggc gttcgccatc cagcgggttg
    20221 gacgtgttca tgcaggtttc ggtcatgcca taacgttcaa ggatcttatg gccggtccgt
    20281 tcaaagaact ggtcgtgcgt ttccgccaga agcggtgccg agccagaaac aaacagccgc
    20341 atgtttgatg taacatcgcg cccgaaaccc gaatgcgcca gaagacgggt atagaaggtg
    20401 ggaaccccca tcagaacggt tgatttcggt agacgttcga tcacgtcatc agcatcgaat
    20461 ttggatagca ggatgatctt gccgccatta agcagcatga tattgaccgc aacaaacagc
    20521 ccgtgggtgt gaaacagcgg cagggcatgc agcaacacgt catcggggcg gaaaccccac
    20581 gcctgatgca gcgtcagggc attcgatgtc aggttgccat ggctaagcat agcccccttt
    20641 gaacggcccg ttgtacccga tgtataaagg atggctgcaa tatcatcgcg ggtgacatcg
    20701 gcaatatcgg tgctggcggc ggcggtggcg gcctcgtcat ttaaggtgcc atcgccattg
    20761 gtgccaaggg tcagaacggc ggcaacatcg tttttgctgg ccaggtcccg ggatgtttca
    20821 aggcggtccg ggcggcaaac
//
