LOCUS       NZ_PJCT01000002        21612 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Bacillus sp. SN32 NODE_2_length_1020527_cov_117.808935, whole genome
            shotgun sequence.
ACCESSION   NZ_PJCT01000002
VERSION     NZ_PJCT01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. SN32
  ORGANISM  Bacillus sp. SN32
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 1020527)
  AUTHORS   Nazipi,S.
  TITLE     Bacillus sp. isolated from nest material of social spiders
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1020527)
  AUTHORS   Nazipi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-DEC-2017) Bioscience, Aarhus university, Ny Munkegade
            116, Aarhus C 8000, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2017
            Assembly Method                   :: SPAdes v. NOV-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 08:36:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,230
            CDSs (total)                      :: 4,121
            Genes (coding)                    :: 4,016
            CDSs (with protein)               :: 4,016
            Genes (RNA)                       :: 109
            rRNAs                             :: 10, 7, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 5, 7, 4 (5S, 16S, 23S)
            tRNAs                             :: 83
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 105
            CDSs (without protein)            :: 105
            Pseudo Genes (ambiguous residues) :: 0 of 105
            Pseudo Genes (frameshifted)       :: 66 of 105
            Pseudo Genes (incomplete)         :: 52 of 105
            Pseudo Genes (internal stop)      :: 19 of 105
            Pseudo Genes (multiple problems)  :: 27 of 105
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:36:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 671992
            Orig. end                         :: 693604
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PJCT01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    complement(88..102)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.21"
                     /tool="antismash"
     gene            complement(180..3866)
                     /locus_tag="CW370_RS11790"
                     /old_locus_tag="CW370_11790"
     CDS             complement(180..3866)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="CW370_RS11790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11790"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_024572780.1"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
     misc_feature    complement(3932..3947)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3956..3969)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3956..3970
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     misc_feature    3997..4011
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            complement(4085..4561)
                     /gene="arfM"
                     /locus_tag="CW370_RS11795"
                     /old_locus_tag="CW370_11795"
     CDS             complement(4085..4561)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="CW370_RS11795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11795"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_024572781.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVENLLRNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4619..4634)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4705..5424
                     /locus_tag="CW370_RS11800"
                     /old_locus_tag="CW370_11800"
     CDS             4705..5424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="CW370_RS11800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11800"
                     /product="YwiC-like family protein"
                     /protein_id="WP_014481214.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5455..6171)
                     /gene="fnr"
                     /locus_tag="CW370_RS11805"
                     /old_locus_tag="CW370_11805"
     CDS             complement(5455..6171)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="CW370_RS11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11805"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003227573.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="CW370_RS11810"
                     /old_locus_tag="CW370_11810"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="CW370_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11810"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_010886631.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLILLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="CW370_RS11815"
                     /old_locus_tag="CW370_11815"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="CW370_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11815"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /locus_tag="CW370_RS11820"
                     /old_locus_tag="CW370_11820"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="CW370_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11820"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_017696263.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFITGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="CW370_RS11825"
                     /old_locus_tag="CW370_11825"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="CW370_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11825"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 2.2e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="CW370_RS11825_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="CW370_RS11825_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="32.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="CW370_RS11830"
                     /old_locus_tag="CW370_11830"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="CW370_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11830"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="CW370_RS11835"
                     /old_locus_tag="CW370_11835"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="CW370_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11835"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_024573031.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 1.2e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.1e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 3e-45, bitscore:
                     150.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.4e-07, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-22, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.3e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 4e-10, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CW370_RS11835_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="CW370_RS11835"
                     /locus_tag="CW370_RS11835"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="CW370_RS11840"
                     /old_locus_tag="CW370_11840"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="CW370_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11840"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /locus_tag="CW370_RS11845"
                     /old_locus_tag="CW370_11845"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="CW370_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11845"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="CW370_RS11850"
                     /old_locus_tag="CW370_11850"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="CW370_RS11850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11850"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_101169642.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSSWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQGKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAVFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="CW370_RS11855"
                     /old_locus_tag="CW370_11855"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="CW370_RS11855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11855"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080262599.1"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADLSFPS
                     SLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVHACDVRGHAPQTSAITSGRIPVNRHVFETETRS
                     AAGPSVLTLGFYCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEKDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGVLRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /locus_tag="CW370_RS11860"
                     /old_locus_tag="CW370_11860"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="CW370_RS11860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11860"
                     /product="pitrilysin family protein"
                     /protein_id="WP_024571996.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 6.1e-14, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPRQNDLLTIKLYWDIA
                     SRILFQLDSPFFQEIQQTYRLEINRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="CW370_RS11865"
                     /old_locus_tag="CW370_11865"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="CW370_RS11865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11865"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_024571997.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMASYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /locus_tag="CW370_RS11870"
                     /old_locus_tag="CW370_11870"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="CW370_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11870"
                     /product="YncE family protein"
                     /protein_id="WP_024571998.1"
                     /transl_table=11
                     /translation="MKKNDLSVLQENCFCFCDEEISREAPFQVPIDTPEGFKVDSAEAS
                     AAVTWSTDNLSCISEPCLIQTGSEPEDIGVRYAVRVQGAITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQMTVEDLLIVPPFYGSPLTVAGILVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTIVKTIPFSAVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFVYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     gene            complement(18360..19715)
                     /locus_tag="CW370_RS11875"
                     /old_locus_tag="CW370_11875"
     CDS             complement(18360..19715)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="CW370_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11875"
                     /product="YncE family protein"
                     /protein_id="WP_024571999.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHSVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTASILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAIAI"
     gene            complement(19712..19942)
                     /locus_tag="CW370_RS21760"
                     /old_locus_tag="CW370_11880"
     CDS             complement(19712..19942)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="CW370_RS21760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11880"
                     /product="hypothetical protein"
                     /protein_id="WP_024572000.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQQFVQANTLPFHILLYLREQCMSEKEVKE"
     misc_feature    19896..19912
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19945..21090
                     /locus_tag="CW370_RS11885"
                     /old_locus_tag="CW370_11885"
     CDS             19945..21090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="CW370_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11885"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_017696253.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21074..21193
                     /locus_tag="CW370_RS11890"
                     /old_locus_tag="CW370_11890"
     CDS             21074..21193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="CW370_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW370_11890"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 ctttatattt gtcctggtcc tcccattgct tcgggtagcc gatgcccggc tttgtttcta
       61 cattattgaa gtacatatat tccgcaccgg aacggtttgt ccacgtgttt ttgcaggtga
      121 cgctgcacgt gtggcagccg atgcatttat ccaagttcat gaccataccg atttgcgctt
      181 taatcttcaa gccaatcgac ctccttcagc ttgcggatga cgacgttcag gtcgcgctga
      241 ttccccgttg gaccgtaata attaaagccg tagctgagct gggcatagcc cccgatcatc
      301 tgggtcggct tgacgtgaat ccttgtcggg ctgttatggg tgcctccgcg gttattcgtc
      361 agctttgtgc cgggcacgtt gatgtggcgg tcctgggcat ggtgcataaa cgccatccct
      421 ttaggaatcc gatgagacaa aaccgctctc gcgacgacaa caccgtttcg gttaaagcat
      481 tcaatccaat cgttgtcttt gatatccgtg tcctctgcat catctttatt catccacacg
      541 gtcggcccgc cgcggaacag cgtcagcatt ggcagagaat caaaatacat gctgtggacg
      601 gaccatttat tatgcggcgt caaataattg aggacgattt cttttccctc ttgatcaggc
      661 cgcttgctca gaaacgggcg atgctggagg atcggtttga atgtcgccat cgtttcaccg
      721 aattccatca tcagttcatg atcgacataa taggattgtc tgcctgtcag cgtccgccac
      781 gggattaatt tttcaacatt cgtcgtaaac ggcgaatacc tgcgccctcc tttttcagag
      841 ccggaaaacg ctggagacgt gatcaccgtt ttcggctggg ctgtaatttg ttcgaacgta
      901 aagcattctt cctcgcgttc ttccgccagg tctttcagct tcaggttcgt gatgttttca
      961 agtgattccc atgctttgac ggcgaccttt ccattcgaag tggatgatag ggttaaaatc
     1021 gcttctgctg cctgctttgc ttcacttata tttggacatc cctttgcgac actgtccgag
     1081 gtgatttctc ccaatctctg tttgagtgat tcatattcat cggctattga ccagctcatc
     1141 ccttttgttc cgctcggctt taaagcaacg ttcggaccaa gtgcagtcat tttatgaaaa
     1201 atgtgtttgt aatcccgttc aacgacttgg atgttcggca tcgtttttcc cggaatggct
     1261 tcacattcgc ctttgctcca gtcattgatt ttgccgaatg gctgggccaa ttcctgcatg
     1321 gtgtcgtgga ggagcggcgt cgcaaccact tctttcacgg gctccatatc gacttcttct
     1381 gccagatcgg aaacggcttt tgacagcgcc ttgaaaatat cccagtctga cttcgattcc
     1441 cacggagccg agatcgcagg agcaaatgga tgaatgaacg gatgcatatc cgtgctgctg
     1501 agatcgtgtt tttcatacca tgtcgccgcc ggcagcacga tatcggaata cagcgccgta
     1561 ccggccattc ggaagtcaag attgattaac aagtcgagct ttccttccgg cgcctgctcc
     1621 cgccatttga tttcttcagg gcggatgctg tcgctgtcgt cattcatcaa accgttcgtc
     1681 gtccccagca aatgcttgag aaaatattca tgcccttttc ctgagcttga gatcagattt
     1741 gcccgccata cgaagagatt tcttgggaaa ttcacttcat tgtcgggatc ttcaatcgcg
     1801 aatttcagtt ttttctcttg gagctgtgag gccacgtacg cacctacgtc ttcaggtgtt
     1861 gctgcccctg ctttttcagc ttctttatac agatcgatgc cattttgatt gaaagtcggg
     1921 taagacggaa gccaccccag ccgcgcggcc agcacattgt aatcagcgtg gtgcttgtag
     1981 cgggatgacg cagcaatcgg tgatgccaaa tcactgatcg gctggtcctc ataacgccac
     2041 tgatctgtcg caaagtagaa aaatgaggtg ccgttttgca gcttgggcac gccctcccag
     2101 tcctttgcag ttgcaatcgt ctgccaccct tcagcaggtc ggagcttttc ctgccccaca
     2161 taatgggccc agcctccgcc gtttacgcct tgggcgccta caagtaaaac aagatttaac
     2221 accgctcggt agatcgtgtc ggagttgaac cagtggttaa tgccggcccc tacgataatc
     2281 atggaccggc cgtctgtatc gatcgcattt tgggcaaact ctctggcaat cttaacgaca
     2341 gcttcttttt tgattcctgt catttgttcc tgccaggcag gcgtaaacgg ctcaggatca
     2401 tcataggaga cagccgatcg ttcgccgatg ccccggttca cgccgtagtt agccagtatc
     2461 aagtcaaaca cggtcgtgat gtacgtttct tcaccgttca ggttcatttt tttaatagga
     2521 agatcccgct cgagcacttt gtttccgtca tttgaaaaat acgggatgcg caccgtgccg
     2581 atttcgtcct ctattcccag cacagagaga cggggttcaa tcggttcccc ggtttcttca
     2641 tcaatcatgt gcaggttcca tttctgctgc ccgtcccagc gcgagcccat tgtcccttgg
     2701 ggtatggcaa atgaacttgt ctgttcatcc caaactgcag gcttccactg atcatgcttt
     2761 gtcttccgcc cgatgtcctt cgcatgcaga aaccgtcccg ctgtgtatac gccattttct
     2821 tttgacagag tgacgagaaa tggaaaatca gtgtattgct tcgcgtactc aataaaacgt
     2881 tcagtttctt ggttcacgta aaattcctgc agaataacgt gacccatcgc catcgcaagc
     2941 gccccgtcag tcccttggcg aatactcagc cagtcatccg cgaactttga ggattccgca
     3001 aaatctggac tgatcgaaat gaccttagcg cctttatagc gggcctccgc caaaaaatgc
     3061 gcgtcaggcg ttctcgttaa cggaacgttg gagccccatg tgataatata gccggaattg
     3121 taccaatcac tgctttccgg aacgtccgtc tggtcacccc aaatttgcgg ggatgctgga
     3181 ggaagatccg cataccagtc ataaaaactg agcatagggc ctccgattaa cgacataaac
     3241 cgggagcctg atgcgtggct gatcatggac atggccggaa tcggagaaaa accgacgttt
     3301 cggtcaggcc cgtatttcat cactgtatac agcagagagg ctgaaatcag cttcagcacc
     3361 tccggccatt cagcgcgcac aaaaccgcct ttccctctcg cctgtttata ggacttcgct
     3421 ttttcagggt tttcgacgat cgatttccag gcttccaatg gattttgatg cgtctgcaat
     3481 gcctcccgcc acaaattgat cagcacaccg cgcacgtatg gatatttcac acgcagcggg
     3541 ctgtagatat accatgaaaa actggccccc cgcgggcagc ctctcggttc aaaatcaggc
     3601 atatccgggc ctgttgatgg ataattcaaa ttttgccctt cccacgtgac aattccgttt
     3661 ttcacataaa tattccagct gcaagaccct gtacagttaa cgccgtgggt ggagcgaacg
     3721 actttgtcgt actgccatct gtttctgtat acattctccc aatcgcgatc ctcgcgggtg
     3781 gtttggctat gtttatttga atggtgttcg ataggagaga aataattcaa tctcctaaac
     3841 aacggactca ttttcttttt cttcatgaga gttcactcct tccgagtcag gtgatgctaa
     3901 gttcactata aacagagaca gcgtgtttcc ttgtgaacta tgtcacacac tctgcttttt
     3961 tcacaaaatg ttcacacaaa ggagaaggaa ggattttcac aagatgtgag gaaggctgcg
     4021 ttcaggcagg acgcttgggt cattagccgc ctttcattca aagatcaaaa aaaaccggct
     4081 ctatttaaga accgggctcg gcgttttcat cctgtgatgt atgcagatac cgcaaaaata
     4141 attgatagga acaaaaaaca ttttgctgaa gcatagccaa aaagttcatt tgcagctgcg
     4201 gatgataaga catcattttc ttaaatatgt aatatgggat attgagaatc agaatgtctg
     4261 aagtggcatt gactgagata aagggcgata aataaagccc gcctttttca tcaatcggaa
     4321 acacatcccc tttttcccac agcgcaacgg ttttcgaccc ttcagggagc cttgtgtcca
     4381 tgaaacggac actgcctttt aatacaatat aaacagattg agaatgaaga aaagatggag
     4441 actgatcaca tgagccgcgg ataaacgtgc cgtttctcag caaattttcg acaatggata
     4501 gaggcacttc attaaacata ggaagttgtt tcagaaataa taaatagtca cactgattca
     4561 taggaaaacc tcctgtgcta aggatagctt tagtgtagct cgatcgagcc tgtacagcag
     4621 tgatgtattt cacagcctgt atgatgaatg tcacttatca ggagggtgac tgcatttata
     4681 atgaaagaaa aaaggaggat ttcgatgaag gcgctgattc cgaagcagca cggcgcgtgg
     4741 gcgatgctgc tgatcccatt tttactcggc atggtcaagg gaggccccgt tatttggcat
     4801 attccgctct tcctaggctg gcttttccta tacttagcgg tttatcccgt tacgcttgcc
     4861 ttaaaaaaga aacaaagcaa accatatcaa aagtggatgt gttattacgg ttttcccgcc
     4921 tgctgctttt tgatgatctc ggtctttcat aagccgcctc tcatctgggt gggcgtttct
     4981 ttactgccgc tgtttctcat acatatgtat tttgcccgca gaaaaaacga acgagcctta
     5041 ttgaatgatg ttgcaggtgt cttgttcttt tgttcgggcg ggtttgcgag ctgctggctg
     5101 gggatgggaa cccttgacgg ctgggcttgg tttattttct tgcagtctgc tttatttttt
     5161 atcgggagtt ccttttatgt gaaatcggtg attcgtgaaa gaaagaacag ggcatttgca
     5221 tactggtcat gggggtatca cctgctgctc ccctttttat ccgctctttt cggagcagga
     5281 tgggcgtttc tcgcttttat cccgagcagc ttgcgggcat ggttttttca tggaagggat
     5341 tggcccgtga aaacgattgg cattctggaa atcgtgaatg cctgcttctt tcttgccgtc
     5401 atgtgcctgt ttatcacaag gtaaaaaaac aaggacacca ctgtccttgt tttttcagtc
     5461 aatattgcaa atctccagcg ggcaattttc acactcaatc tcacatcgta aatagtcccg
     5521 cttgtgcaaa ataatttttc cggattcgtc tatcgaaata accccttttt tgcggagatc
     5581 tccgagcata cgattgacgc tttcccgtgc agccgcgcaa aactttgcca aatcctgatt
     5641 tgtcaggaca atgttaatca gaatgccgtc gcttcgctcc actccgtagc tgtttgataa
     5701 gcggataagg gtagaataga gcgccccctt tttgccatga agaagcagat ccctgatttt
     5761 ggactgaatc ttccggaggt gcgtgctcat ccatttcatg aactcaaatg tcaaagcgcc
     5821 gttttggatt aattcttttt ccagcttatt tttattaatg acgagcacct cgccatcctc
     5881 tagcactttt gcactgagca tataccttgg ttcttcagtg aaaagtgtta attcaccgac
     5941 gatatcatgc ttttggcaga ttctaagcgt caggtctttt ccgtcagatg tcagcttgcc
     6001 gatttcaatg agtcctgatt gaatcagata aagctcttct gcatccattc cttctcgaaa
     6061 caaatacgtg tgtttttcca tttttctttt cgtgctgatc gattccagca attcatgcag
     6121 atcgctggat ataagatcac tatcagatgg tcgaacagag agaaaattca tgagctcacc
     6181 tcgaagaaag tcacgttgtg tgtttattgt aacgtgaatt gatttgtacc catcgagaaa
     6241 aaactaacaa tcttgtgaat gccccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaaact ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa cacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttcgaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatg
     6541 cctgagcaga cggccacggt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcctgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc gaacaacacg tgcagtaagg caaagacagc cagcaaaatc
     6961 agatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc actccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagagt ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gcctcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat cgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg ccaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgatcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagttagtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgtgc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg cattgcaaag
     8041 aagtaacgaa cagcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaaggtgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt cgattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agaaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaaa gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcaat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgaagct tttccagctc gtatttcagg ccgtattcac ggaaaaacgc gaggcgttca
     8581 ctttcctctt cgttaacgaa acgatcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct caccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg ttcgtttccc cgtatgcttc ccctgcttcc
     8941 agtacagacg gaatcagctt tgttaaatac tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gccttccctt tatcaaaatg ggcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccagctgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttatgaa acgctgattc attttgacag
     9481 cccctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgta ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatcc ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtg atccagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg tggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcgt tctcttacaa ttgggttgat gatttcggaa
    11161 gaggcaggga tattgtccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgaaagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcaa gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcgggatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttactt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 taggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtc ttttatcaga aaatgcgtga gtactgtgaa gcaggcggaa ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gatgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat tgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctt
    12721 catggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gttcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagggcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggtattcagc ggcttctttt
    13261 cgttccagat gatgaacacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgga
    13381 tgttgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctattttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatttcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacaattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaatcat tgacgctttt ggttatgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgatgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgaaaatc
    14161 gaaaagaaat tcactgatcc cttctcctac tctgcggctc gcttggctga ggaggtcttt
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acatgcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctataacgt ccggaagaat acccgtaaac cggcatgtgt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga ttttactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagaa agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatggggg tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgcgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gattcccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctatcaagcc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatggtgctg ggtgatgagg agcgaatgga
    15721 agatacctgg accggattac agatcggcgc acttcctagg caaaacgatc tgttgacgat
    15781 aaagctttat tgggatatcg cgtctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agaaattcag caaacgtacc gtctggaaat caatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggattct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcgtct tattccttcg gctgggttca ggccgtggcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgacg ctgtgcggct cgggctgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcatta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gcctccacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacttat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg ggcactggcc
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctgcca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta cgtataagtt attaatgaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtgc tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa atttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgaatcta tgatactttc taccaactgc
    17401 ccagtattta catcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tacgaactca
    17581 tctgttggat caaattcgat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat tcccatggag aacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacag cagaaaacgg gattgttttt
    17761 acaatagtgt ttaaatctgc atcaatgact gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggtgatggc ggtaaaacaa gtatcccggc caccgtgagc
    17881 ggactgccgt agaaaggcgg cacaatgaga agatcttcca ctgtcatttg actaaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc agtatgaatc
    18001 acagaaacag ccccgtctcc ttgtccatat tgatttcgta caggcgacac actgacaaga
    18061 agcgtaatgg ccccttgtac tctcacggca tatcgaacac cgatatcttc tggttccgac
    18121 ccagtctgga ttaagcaagg ctcactgata caggacaaat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag gggtatctat cggcacttga
    18241 aacggcgctt cccggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaaaca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcaccaca catagttaat
    18361 taaatcgcaa tagctcccgg tgaaacccca agagatatga cagtctccac ggagtaatca
    18421 tccgtgttgt aaacagtgat gctctgttct aggacatgag ttgcatacag aaactcgcca
    18481 ttcggggtaa acgcaaagtc tcttgccgac tgcggaacat ttcctataac gcctgctcca
    18541 tttggactga ctgaatataa attgccagtg aagccgtcat ataaatacac ctctgctcca
    18601 ctcgtaaaca ttcgatattc cccttcatac tccagctctt gggtgctgct gatggtaaac
    18661 gtatttaaat caataaccgt caaataatta aaaaagaatt cttgttctaa tacataggca
    18721 taccgctccg gccaatttgt ttctatggtt gatacgataa gctctcgttc aattgttcct
    18781 gtgacttcac cggtagttag gtccactttt tgcactatac caaaattaag aacataggcg
    18841 aataacccat tgggatcgat tgcaacatca tacccttcca caggaatcga cctatccaca
    18901 gttaacgtat caattccaat cacataaacc gcagtaccgg tgaaaacata agcaaactca
    18961 tgattaggga taaatctaat caatcgaggc ggctgatcca gcaatataga tgctgtcact
    19021 gttaatgtgt cataatcgat gacagaaatc acattgttgt tgggatgtaa gacaaacaca
    19081 gcgcttttat ccggggtaat ttcaatacct gccggattgt acggaagagc aatcgttgtc
    19141 acaacagaat gagtgtttgt atcaatcaca gaaactgatt gatcatttgg attcgctgta
    19201 aacgcataaa cgggttccgg ctccggtaca agcacaatcg tccccgtcac cgataaagga
    19261 ctgccgtaaa acggcggaac aacaacaagg ttctcaatcg tgatgtcact gatatccggg
    19321 caatcatccg gttcatcgga ataatagacg acttgatcga tctctgcatt gtgaatgacg
    19381 gaaacagccc cgtccccttg tccatattga tttcgcacag gtgagacact gacgagtagc
    19441 gtaacggttc cctgcaggcg cactgcaaat tgaacaccga cctcatcagg ctcaggcccc
    19501 gtttgaatta agcaacggtc actgacacaa gaaaggctgt ctgcattcca cgtcacgttt
    19561 gcaacagctt cagccggatc aacgacaaac ccttcaggta attcaatcgg tgcttgaaac
    19621 atggcttctc ggcttgcttc tccctcacaa aaacataagc actcttcttg ttctgctcct
    19681 gctttttctt taaaggaaag cttgtttttt ctcattcctt cacttccttt tcagacatac
    19741 actgctcacg cagatataac agaatatgga agggtaacgt gtttgcttgt acaaattgct
    19801 gagggtaaaa gcttcttttt gaaaatatat ctccaaacat gcggtgtaac gaaagaaaaa
    19861 attgcggttt ttttgcgctt ctcacaagaa tgttgatgat aaaatatgac atatatagaa
    19921 ttatgaaggg agggatttgc aaacgtgaca ggtgtcatat cttcttcttc catcggagaa
    19981 aagattaacg aatggtatat gtacatacgc cgattcagca tacccgatgc agaatatttg
    20041 cgacgagaaa tcaagcaaga gctggatcaa atggaagaag atcaagacct tcatttgtac
    20101 tattcactaa tggagtttcg gcacaacctg atgcttgagt accttgaacc gttagaaaaa
    20161 atgaggattg aggaacagcc gagactgtct gatctgctgc ttgagattga taaaaaacag
    20221 gctcgtttaa ctggtctgct tgagtactat tttaatttct tcagaggcat gtatgagctg
    20281 gatcgccgtg aatatgtatt agccattcaa ttctttaaaa aagctgagag caagctggtt
    20341 tttgtgaaag ataaaatcga taaagctgaa ttctttttca aaatgtcaga agtctattat
    20401 tatatgaaac aaacttatgt ctccatggac tatgcacgtc aagcattcga aatatacagt
    20461 gaacagacta catatgatat cagaatgatt caatgccagt ccttattcgg agccaacttt
    20521 ttggatttaa aacaatacga aaaagcaatt gcccattttc aaaaagcctt tacacttgca
    20581 aaaacagagc agcagcccca attaatggga agaacacttt ataacatagc actctgcaag
    20641 caaaaccaaa acagttttga atcagcgata gagtatgtaa aaaaatctat tcaagtattt
    20701 gaaggatcta aaatgcttcc ttcactgcca caagcttttt tcctaattac acaaatttat
    20761 tttaaattag gtaagattga taacgcctgt gaatatcata aaaaaggaaa agagtattct
    20821 gcagctgcgg gagataccgt gtatctaacg gagtttgaat ttttggaatc tttatacttg
    20881 tctggaccgg atgaggaacg gatagaaaaa tgttttgttt ttcttgaaag taaaatgatg
    20941 tatgcagata ttgaggactt cgcacttgat gttgctaaat attatcatca acaggaaaat
    21001 tacaaaaaag catctcatta ctttttaaag gttgaagaag caagacagca cattcaaggg
    21061 ggggtgaatt tatatgaaat ggaagtataa attattactc gcttgtttag ctgtgagtgc
    21121 tgtatttatc acagtcgaag tatcaaattc atcaacagaa cattttgatg ttgcacaacg
    21181 cgccatgatc taaaccgccg tccatcggcg gtttttttgt cccctcttta ccaaagtctc
    21241 ccaatccacg ctatgatctt ttcaataatc ttgaagagag tggaaatgca gcatgtctct
    21301 aaaaagtgtg agaacccact ttacacaatg gaatcgagaa aatgatgtga cggagttcga
    21361 aacgtcgagc gcgacagttg aacaggcagc tgagatgacc ggcgtgagcc cggctagaat
    21421 cgccaagacc ctgtccttca gaggggaagg agatcaggcg attctgattg tggcagccgg
    21481 cgatgccaag attaataaca aaaagttcag gcaaacattt ggctttaaag caagaatgct
    21541 ctctcctaat gaggtactgg agcagacagg ccatgaaatt ggaggtgttt gcccatttgg
    21601 gttggctcat ga
//
