LOCUS       NZ_PIZP01000001        20819 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Staphylococcus shinii strain INIFAP 005-08 NODE_1, whole genome
            shotgun sequence.
ACCESSION   NZ_PIZP01000001
VERSION     NZ_PIZP01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Staphylococcus shinii
  ORGANISM  Staphylococcus shinii
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 560068)
  AUTHORS   Lopez,G. and Munoz,A.
  TITLE     Phylogenomics unveils the most efficient molecular markers for the
            species phylogeny - the case of the genus Staphylococcus
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 560068)
  AUTHORS   Grana-Miraglia,L., Miranda-Mirand,E., Arreguin,C., Cossio-Bayugar,R.
            and Castillo-Ramirez,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-DEC-2017) CCG, UNAM, Av. Universidad, Cuernavaca,
            Morelos 62210, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-FEB-2017
            Assembly Method                   :: Spades v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 337.1969x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002836835.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 11:05:21
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,976
            CDSs (total)                      :: 2,900
            Genes (coding)                    :: 2,859
            CDSs (with protein)               :: 2,859
            Genes (RNA)                       :: 76
            rRNAs                             :: 7, 4, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 3 (5S, 16S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 22 of 41
            Pseudo Genes (incomplete)         :: 25 of 41
            Pseudo Genes (internal stop)      :: 13 of 41
            Pseudo Genes (multiple problems)  :: 13 of 41
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:11:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 308055
            Orig. end                         :: 328874
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PIZP01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20819
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20819
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20819
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10819](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10819)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(720..1322)
                     /gene="ruvA"
                     /locus_tag="CW747_RS01500"
                     /old_locus_tag="CW747_01500"
     CDS             complement(720..1322)
                     /EC_number="3.6.4.12"
                     /GO_component="GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA]"
                     /GO_function="GO:0009378 - four-way junction helicase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="ruvA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500257.1"
                     /locus_tag="CW747_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01500"
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="WP_039068314.1"
                     /transl_table=11
                     /translation="MYAYIKGTLAVLNPTHVVVEASGVGYEIQTPNSYRFQKFMDQEVV
                     IHTSLIVREDAQLLYGFINQEEKDMFLSLIKVTGIGPKSALAILASSSPNEVKIAIENE
                     NDSYLTKFPGIGKKTARQIVLDLKGKVQINEVDSSQILNVEASLSDNTPIIKEALLALE
                     ALGYSKRELTKVEKALAKETFESVDDAVKKGLQLLIS"
     gene            complement(1335..1790)
                     /locus_tag="CW747_RS01505"
                     /old_locus_tag="CW747_01505"
     CDS             complement(1335..1790)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500258.1"
                     /locus_tag="CW747_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01505"
                     /product="ACT domain-containing protein"
                     /protein_id="WP_017724673.1"
                     /transl_table=11
                     /translation="MDKKDYKKFYLIREDVLPESVVKTLKIKEVLKNDPSLSIFEAVKQ
                     FDLSRSAFYKYRDTIFPIDEKMESTREFTLILYVNDIVGMLAEVLNTLSSLSLSVLTIH
                     QSIPMESRATITLSLDAKGTNLEIDDVMEALRVIDHVSKVELISMTI"
     gene            complement(1803..3098)
                     /gene="obgE"
                     /locus_tag="CW747_RS01510"
                     /old_locus_tag="CW747_01510"
     CDS             complement(1803..3098)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="obgE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444729.1"
                     /locus_tag="CW747_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01510"
                     /product="GTPase ObgE"
                     /protein_id="WP_101049505.1"
                     /transl_table=11
                     /translation="MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGDGASII
                     FEVDEGLRTLLDFRYQTHFKAKRGDAGQSSNMHGKNAEELVLKVPPGTIIKSVETEEVL
                     ADLVENGQRAVVAKGGRGGRGNSRFASPRNPAPDFSENGEPGEEIEVTLELKLLADVGL
                     VGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTKDQRSFVMADLPGLIEGASE
                     GVGLGHQFLKHVERTKVIVHMVDMSGSEGRDPYEDYKVINEELNAYEHRLEERPQIVVA
                     NKMDMPNAEENLEAFKEALNDDSLHIIPLSTFMHDHIDELLYAIADKLEEVKDIDFSKD
                     EEEDLGVNRVIYKHTPSQDKFTITRDDDAAYVVSGKAIERMFKMTDFNSDPAVRRFARQ
                     MRSMGIDEALRARGCKNGDIVRILGGEFEFVE"
     misc_feature    complement(3087..3101)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            complement(3230..3514)
                     /gene="rpmA"
                     /locus_tag="CW747_RS01515"
                     /old_locus_tag="CW747_01515"
     CDS             complement(3230..3514)
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500260.1"
                     /locus_tag="CW747_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01515"
                     /product="50S ribosomal protein L27"
                     /protein_id="WP_101049507.1"
                     /transl_table=11
                     /translation="MLKLNLQFFASKKGLGSTKNGRDSVSKRLGAKRADGQHVTGGSIL
                     FRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAAAE"
     gene            complement(3527..3847)
                     /locus_tag="CW747_RS01520"
                     /old_locus_tag="CW747_01520"
     CDS             complement(3527..3847)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633692.1"
                     /locus_tag="CW747_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01520"
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="WP_101049509.1"
                     /transl_table=11
                     /translation="MITVDITLNDVGQITDVIMDGHAEHGEYGHDIVCAGASAVLFGSV
                     NAIMGLTTEKPDIDYNDDGGHFHVRSVDTSNEQAQLILQAMLVSLQTIEEEYKENIRLN
                     YK"
     gene            complement(3850..4158)
                     /gene="rplU"
                     /locus_tag="CW747_RS01525"
                     /old_locus_tag="CW747_01525"
     CDS             complement(3850..4158)
                     /GO_component="GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457386.1"
                     /locus_tag="CW747_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01525"
                     /product="50S ribosomal protein L21"
                     /protein_id="WP_017724677.1"
                     /transl_table=11
                     /translation="MFAIIETGGKQVKVEEGQEIFVEKLDVNEGDSFTFDKVLFVGGDA
                     VKVGAPTVEGASVTATVKKQGRGKKITVFTYKRRKDSKRKKGHRQPYTKLTIDKINA"
     misc_feature    complement(4171..4244)
                     /db_xref="RFAM:RF00559"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
     gene            complement(4274..4798)
                     /gene="mreD"
                     /locus_tag="CW747_RS01530"
                     /old_locus_tag="CW747_01530"
     CDS             complement(4274..4798)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mreD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002507406.1"
                     /locus_tag="CW747_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01530"
                     /product="rod shape-determining protein MreD"
                     /protein_id="WP_069792190.1"
                     /transl_table=11
                     /translation="MRALYYFLIGIVLFYIDTAIGLIIPMQIGTKDIIFVPHLTLMYLL
                     IICVYRSFGVAIILSTVLGLITDLYFGSFYGLYLFGYILFVVIQDFFFKTFYRDYTMLF
                     FVVLLSTIFLEIYVAIIYSVLGLIAFNLFEFVLYRLIPTLGLNFILLIIFYPIITKFFR
                     KVQLKIDSKKP"
     gene            complement(4798..5640)
                     /gene="mreC"
                     /locus_tag="CW747_RS01535"
                     /old_locus_tag="CW747_01535"
     CDS             complement(4798..5640)
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mreC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012083861.1"
                     /locus_tag="CW747_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01535"
                     /product="rod shape-determining protein MreC"
                     /protein_id="WP_039068318.1"
                     /transl_table=11
                     /translation="MSKFFKNNKLIVILCAIIVFIALIGVSLRSQSQSPVEQYVGDSVA
                     FGQRAVSYPVHFVTGSINNLFAKDSSKEQNSKVKQLEAENERLKSENKKYKKELDIEDI
                     SKFEPISSTVLSRNPDQWMNTLVINQGAKDGIENNMAVMTSEGLVGRISKVNQFSSQVD
                     LISTNTRANRLSVNIQHDDKNVFGLIDHYDSKNEELIITDINNKDSVKKGDKVVTSGLA
                     DQLPSSIYIGEVSKVENDEYGLSKEVRVKTAANLSDLNHVYVAKRDPKTIPDNESGDN"
     misc_feature    6139..6153
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.2"
                     /tool="antismash"
     misc_feature    6139..6154
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    6472..6485
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     misc_feature    complement(6522..6536)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.46"
                     /tool="antismash"
     gene            complement(6651..6812)
                     /locus_tag="CW747_RS14860"
     CDS             complement(6651..6812)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724680.1"
                     /locus_tag="CW747_RS14860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_172643883.1"
                     /transl_table=11
                     /translation="MSEQSKDKKVDEQAKAQNLFARWRKEETLYKEDEKEAEKEAEKSS
                     ETSDEEEK"
     gene            complement(6883..7341)
                     /locus_tag="CW747_RS01540"
                     /old_locus_tag="CW747_01540"
     CDS             complement(6883..7341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302941.1"
                     /locus_tag="CW747_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01540"
                     /product="DUF4930 family protein"
                     /protein_id="WP_039068319.1"
                     /transl_table=11
                     /translation="MRFIFSIIKNFIAIIAIIVIVFFALKYAPFLKDQQWNPVHNNEPP
                     TSNMQTEGDLTGGQRYSVEDNDILKNVPRSQAKNVFDWIDKKEFMSVSGIGRMGYSDKY
                     LAGQRGDEFIIYKFGSDSIRVYKTEIEMEQDLNQLGEHIELQPPSNYE"
     gene            7491..7667
                     /locus_tag="CW747_RS01545"
                     /old_locus_tag="CW747_01545"
     CDS             7491..7667
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468500.1"
                     /locus_tag="CW747_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01545"
                     /product="hypothetical protein"
                     /protein_id="WP_101049511.1"
                     /transl_table=11
                     /translation="MSIISIILLALLVILLFRVGLSILRFLIYVGIIVLCIYLGYQGIL
                     WIMENFNSYFSFI"
     gene            complement(7912..8193)
                     /locus_tag="CW747_RS01550"
                     /old_locus_tag="CW747_01550"
     CDS             complement(7912..8193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724682.1"
                     /locus_tag="CW747_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01550"
                     /product="hypothetical protein"
                     /protein_id="WP_039068320.1"
                     /transl_table=11
                     /translation="MGTILLIGLLLPVIYLMQLVKNQKPIDFKSTKKTVIISIVGILLT
                     TMLFFIFNTNHTSFWLYLIGALIIAIIWALLLCGCYYFYQVLSNNVKK"
     gene            complement(8340..9017)
                     /gene="radC"
                     /locus_tag="CW747_RS01555"
                     /old_locus_tag="CW747_01555"
     CDS             complement(8340..9017)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="radC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468499.1"
                     /locus_tag="CW747_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01555"
                     /product="DNA repair protein RadC"
                     /protein_id="WP_039068321.1"
                     /transl_table=11
                     /translation="MKIKELANNQKPRERLLNNGPTHLSDAELLAILINTGRKGCSSLD
                     IANELLKSVETLKQLKALSINDLNKVKGIGLYKALILKAAFELGERMHSGSLEEKIQIT
                     SPQDVANFMMGKMEHLTQEKFIALFLNSKNVIIKQKTIFIGTLNSSIVHPREIFSEAVK
                     CASNAIVVLHNHPSGDTTPSKEDIRTTDRLRECGVILGIDVLDHIIIGDHAYLSMVEEG
                     YFD"
     gene            complement(9020..9724)
                     /locus_tag="CW747_RS15200"
                     /old_locus_tag="CW747_01560"
     CDS             complement(9020..9724)
                     /EC_number="3.4.23.43"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018460.4"
                     /locus_tag="CW747_RS15200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01560"
                     /product="prepilin peptidase"
                     /protein_id="WP_338092278.1"
                     /transl_table=11
                     /translation="MLVTLLLIYPILFSFLYQLCFVEKLELSYLTLRSRCDDCLKEIRL
                     LELIPVLSFIFLRGTSSCCNRKINIFYLIGELLSLIPLFYIFYVPHNLIDNATLLLIYL
                     FLLVLAIYDLKTYTVPLHVIVVFAICICFITPLHIMSFLFVTSLLHVFYILFHNAIGYG
                     DIIIFSLLALALPSIEFSIILLFTFICGGLFALFILLVFHNESSKIPLIPFIYLAFNIT
                     LLTYQNFVFGGF"
     gene            complement(10001..10819)
                     /locus_tag="CW747_RS01565"
                     /old_locus_tag="CW747_01565"
     CDS             complement(10001..10819)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269366.1"
                     /locus_tag="CW747_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01565"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_101049515.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.6e-13, bitscore:
                     45.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.1e-29,
                     bitscore: 96.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKKFPKDAMRVLKETSRTFYIPITFLEKELKHTVASAYLVLRA
                     IDEIEDHEELDNGLKHSILMQVSELFKAPFDEVKYMQILEPVKSKMPEVTLRLGEWIEA
                     CPSKTLPIVLDASSEMAFGMAKWAKANWDIHTKDDLDDYTYYVAGLVGVMLSQLWDLCA
                     NVKTDRELAIGYGRGLQAVNILRNEQEDFAERGVSFMPDDWTRDDLFNYAEDNLAKADA
                     YMKDINKKTILLFCRLPLALAHKSLKAMKNGREKISRKEVEETVDEIQKD"
     misc_feature    complement(10913..10928)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 26.45"
                     /tool="antismash"
     misc_feature    complement(11020..11035)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.99"
                     /tool="antismash"
     gene            complement(11067..12332)
                     /locus_tag="CW747_RS01570"
                     /old_locus_tag="CW747_01570"
     CDS             complement(11067..12332)
                     /EC_number="6.3.2.-"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002457793.1"
                     /locus_tag="CW747_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01570"
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="WP_039068324.1"
                     /transl_table=11
                     /translation="MNYLDSLYWIHERTKFGIKPGVKRMEWMLDRLNNPQFNINGIHVG
                     GTNGKGSTVSYLRSALVDNGYEVGTFTSPFIETFNERISLNGVPISDDDIVKLVQKVKP
                     VSEALEVETDLGTATEFEIITTMMFLYFGEIHPVDFVIIEAGLGIKNDSTNVFKPILSI
                     LTSIGLDHTDILGDTYVDIAKDKGAIVKPNTPIIYAVKNEEALKVIRDYVEQQNAEGIE
                     LDRDISIISEDEEFTYRYKDYELETLLLNMLGEHQKENAALAITALIELNESDIVDLDF
                     NKMIDGIESVSWTGRIEQVKERPLMIVDGAHNVESVEALISTMKNYYHTENIDILFSAI
                     KGKPLNAMVDQLKTIASTFYITDFDFPKALTKEAIFDEVRFDQKALVDDYVKFIESYNG
                     DGLIITGSLYFISEVKAKVDFS"
     gene            complement(12344..14974)
                     /locus_tag="CW747_RS01575"
                     /old_locus_tag="CW747_01575"
     CDS             complement(12344..14974)
                     /EC_number="6.1.1.9"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500272.1"
                     /locus_tag="CW747_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01575"
                     /product="valine--tRNA ligase"
                     /protein_id="WP_101049517.1"
                     /transl_table=11
                     /translation="MEMKPKYNPNEVESGRYDQWVNNGYFKAKEDSSKETYTIVIPPPN
                     VTGKLHLGHAWDTTLQDILTRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGLSRH
                     DLGREKFLEQAWDWKEEYATFIREQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDMYN
                     KGLIYRGEYIINWDPIARTALSDIEVIHEDVEGKFYHFKYPYADGDGFIEIATTRPETM
                     LGDTAIVVNPNDERYKDVIGKKVILPILGRELPILADEYVDIEFGSGAMKVTPAHDPND
                     FEIGNRHDLERIIVMDEAGKMNDKAGKYQGMDRFDCREQLVKDLEAEDLVIKIEAHEHS
                     VGHSERSGAVVEPYLSTQWFVKMKPLAEQALDNQKTDDRIDFVPARFEKTFNRWMEEIR
                     DWTISRQLWWGHQIPAWYHKETGEIYVGESAPEDIENWTQDEDVLDTWFSSALWPFSTL
                     GWPDTEAEDFQRYFPTNALVTGYDIIFFWVARMIFQGLEFTGKRPFNDVLLHGLVRAED
                     GRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWN
                     AARFSIMNIGEDFKVEEVDLSGNLSLADKWILTRLNETIANVTDLSDKYEFGEVGRTLY
                     NFIWDEFCDWYIEMSKIPMNGEDEAQKQVTRSVLTYVLDNTMRMLHPFMPFVTEQIWQN
                     LPHEGETIVNASWPKVNDALTFDDSKETMQQLVEIIKSVRQSRLEVDTPLSKAIPIFIK
                     AKDDNIKDTLLNNSNYIDRFCHPSELTIDTDIEIPEKAMTSVTTAGEVVLPLEGLIDMD
                     KEIERLENELLKWEKELDRVNKKLANENFVNKAPEKVINEEREKKQTYQEKYDGVKLRI
                     NQLKA"
     misc_binding    complement(15017..15257)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            15316..15894
                     /locus_tag="CW747_RS01580"
                     /old_locus_tag="CW747_01580"
     CDS             15316..15894
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724688.1"
                     /locus_tag="CW747_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01580"
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="WP_101049519.1"
                     /transl_table=11
                     /translation="MNECAFGTKDPLYLHYHDEEWGQPIYDSLKLFKLIALESQHAGLS
                     WLTILKKKESYEQAFYNFDPIKISKMTTDDIERLMTFPNIVHNRKKIEAIVSQAQGYFD
                     IEKDYGSFSDFLWSFVDHKPIDCGYTMASDRITVDERATELSKQLKKYGFKFLGPVTVF
                     SFLEAAGLYNAHLQSCPNNPKVYNGKGFD"
     gene            complement(16051..17136)
                     /locus_tag="CW747_RS01585"
                     /old_locus_tag="CW747_01585"
     CDS             complement(16051..17136)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002507391.1"
                     /locus_tag="CW747_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01585"
                     /product="AbrB family transcriptional regulator"
                     /protein_id="WP_039069396.1"
                     /transl_table=11
                     /translation="MSKQLRNNIIVLSLAILLSLILNSANILLPFMFGPIIASVICVRC
                     FHMEVEWPFWLSQIGLVLLGVQIGSTFTENVIFDIKDDWLTIILITVMLLGLALIIAFF
                     FKKIANVNTETAILSVIPGALSQMLIMAEENKKANIMVVSLTQTSRIIFVVILVPFISY
                     FFQGSGDNRSAKDSVVNTLTEALTIPNILLLALAVFLVYVIMGKINFPTRQLLAPILVL
                     ICWNLLTGVTFTLDNYIIAAAQVIYMIRIGIQIAKLLDQMKGRIAVAIAFQNILLILLT
                     FVMVLLIAMVSDHSVNELFLGAAPGGMSQIVLVAIETGADVALISSYHIFRIFFILFLI
                     APLLSYFLKYRVAKDSINKKF"
     gene            complement(17231..18514)
                     /gene="hemL"
                     /locus_tag="CW747_RS01590"
                     /old_locus_tag="CW747_01590"
     CDS             complement(17231..18514)
                     /EC_number="5.4.3.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-361). E-value: 1.8e-72.
                     Score: 236.1. Matches aSDomain:
                     nrpspksdomains_CW747_RS01590_Aminotran_3.1"
                     /codon_start=1
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002507390.1"
                     /locus_tag="CW747_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01590"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_101049522.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.5e-75, bitscore:
                     247.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYSNSEKAMEKAQHLMPGGVNSPVRAFKSVDTPAIFMDHGEGSR
                     IYDIDGNAYIDYVLSWGPLILGHKNKQVIDKIHEAVDKGTSFGASTTLENKLAELVIDR
                     VPSIEKVRMVSSGTEATLDTLRLARGYTGKNKIIKFIGCYHGHSDSLLIKAGSGVATLG
                     LPDSPGVPEGIAKNTITVPYNDLEAIKVAFEEFGDDIAGVIVEPVAGNMGVVPPVEGFL
                     QGLRDITTKYDSLLIFDEVMTGFRVGYNCAQGYFDVTPDLTCLGKVIGGGLPVGAFGGK
                     KEIMDHIAPAGDIYQAGTLSGNPLAMTSGYETLVQLKPETYDYFNKLGDQLEAGLKAVF
                     TKHNVPITVNRAGSMIGYFLNEGPVTNFEEANNSDLEMFSQMYREMANEGVFLPPSQFE
                     GTFLSTAHTEEDIKQTIEAFDTALSRIV"
     aSDomain        complement(17432..18403)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CW747_RS01590_Aminotran_3.1"
                     /evalue="1.80E-72"
                     /label="CW747_RS01590_Aminotran_3.1"
                     /locus_tag="CW747_RS01590"
                     /protein_end="361"
                     /protein_start="37"
                     /score="236.1"
                     /tool="antismash"
                     /translation="MDHGEGSRIYDIDGNAYIDYVLSWGPLILGHKNKQVIDKIHEAVD
                     KGTSFGASTTLENKLAELVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGKNKIIKFI
                     GCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLEAIKVAFEEFGDDI
                     AGVIVEPVAGNMGVVPPVEGFLQGLRDITTKYDSLLIFDEVMTGFRVGYNCAQGYFDVT
                     PDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPAGDIYQAGTLSGNPLAMTSGYETLVQLK
                     PETYDYFNKLGDQLEAGLKAVFTKHNVPITVNRAGSMIGYFLN"
     gene            complement(18528..19508)
                     /gene="hemB"
                     /locus_tag="CW747_RS01595"
                     /old_locus_tag="CW747_01595"
     CDS             complement(18528..19508)
                     /EC_number="4.2.1.24"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hemB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724694.1"
                     /locus_tag="CW747_RS01595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01595"
                     /product="porphobilinogen synthase"
                     /protein_id="WP_039069373.1"
                     /transl_table=11
                     /translation="MQFDRHRRLRSSKSMRSMVRETHIRKEDLIYPIFVVERDNVKEEI
                     KSMPGIYQISLNLLGDEIKEAYDLGIRGIMFFGVPNEKDAVGTGAYDHNGIIQEATRKA
                     KSMYSDLLIVADTCLCEYTDHGHCGVINEETKDVDNDKSLPLLVKTAISQVEAGADIIA
                     PSNMMDGFVAEIREGLDKAGYHNVPIMSYGIKYSSSFFGPFRDAAESAPQFGDRKTYQM
                     DPANRREALRELDSDLNEGADMMIVKPALSFLDIIRDVRNTTNVPVVAYNVSGEYSMTK
                     AAAINGWIDEKAVVMEQMISMKRAGADMIITYFSKDICRYIDEEQ"
     gene            complement(19498..20184)
                     /locus_tag="CW747_RS01600"
                     /old_locus_tag="CW747_01600"
     CDS             complement(19498..20184)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724695.1"
                     /locus_tag="CW747_RS01600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CW747_01600"
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="WP_101049524.1"
                     /transl_table=11
                     /translation="MRPVIVMTQTSEFKRNDACILHRPFIRVQPLSFDLNLLNVNYDWL
                     IFSSKNAVKFFQPYLTRVKVDKIAVIGEKTADYCKSLGLKVSFCPKDYSQEGFLESFCA
                     GEGSKILLPSSSAARSLLQDELHNQKYIVQKIDLYKPVPHTDNICEVKMMIKKNEIDAV
                     AFASSSAVRYFFNHEEPVNFEHYFVIGLQTLETLYEYDAKGTVSEIQTLESLVNKIIES
                     WETNAI"
ORIGIN
        1 cacgaacgcg ttttaataat ctattggcca ccctaggtgt gcctcgacta cgttttgcta
       61 actctatagc actttcttca tcaattgaag taccaagtac ttctgcagta cgcacaataa
      121 tttcttttaa ttcatgttct ttataatatt ctaatctcag gtgtacacca aatctatctc
      181 tcaacggcgc cgtcaaacta ccggcgcgtg tggtcgcacc aattaatgta aatggcggta
      241 agtctatacg tatactacgc gcttcttcac ctttgccaat aacaatatct agaaagaaat
      301 cttccattgc tggatacaga acttcttcta ctacactgct tagtctatga atttcatcta
      361 taaataaaac atcaccaggt tgcaagctag acagaattgc agctaaatct cctggtcttt
      421 ctatagaagg accggaaatt gttctaatat tgacatccat ttcatttgca ataatgttag
      481 acaatgtcgt tttacctaat ccagggggcc cgaacagtag cacatggtct aatggttctt
      541 gtctaatctt agctgctttt ataaacacct ctaaattcga tttaatcgtt gattgaccta
      601 tgtactgacg taatttagtc ggtcgcaatg aaaactcaaa tgaagattct tcatcatgca
      661 tagactgatc taccattcta tcgtccattg tttacacccc ttttaaatat tatttataat
      721 tatgaaatca ataattgtaa acctttttta actgcatcat ctacagattc gaaagtctct
      781 tttgctaatg ctttttccac ttttgttaac tctcgttttg agtatcctaa tgcttccaat
      841 gctaagagcg cttctttaat aatcggtgta ttatcactga gtgatgcttc aacatttaat
      901 atttgactac tatctacttc atttatttga actttccctt taagatctaa tacgatttga
      961 cgtgctgttt ttttaccaat accagggaat tttgttaaat aagaatcgtt ttcgttctct
     1021 atcgctatct taacctcatt aggcgaacta ctcgctaata tagctaacgc agattttgga
     1081 ccgatgcccg ttactttaat taagcttaaa aacatatctt tttcttcttg gtttataaat
     1141 ccataaagaa gttgagcatc ttctctaact attaatgacg tatgaattac aacctcttga
     1201 tccataaact tttgaaaacg gtaagaattg ggtgtttgaa tttcatatcc tacaccggaa
     1261 gcttccacaa ctacatgtgt aggattcaaa actgctaatg tccctttaat atatgcatac
     1321 atagttacac ttccttatat agtcatacta attaattcta ctttagaaac gtgatcaata
     1381 actcgcaacg cttccataac atcatcaatt tctaaatttg tgcctttagc atctaatgaa
     1441 agtgtaatcg tcgctctact ttccattggt atactttgat gaattgttaa tactgacaaa
     1501 cttaaacttg ataaagtatt taaaacttct gccaacattc ctacgatatc attcacatat
     1561 aatattaatg tgaattcacg tgtagattcc attttttcat caataggaaa tattgtatct
     1621 ctatatttgt aaaacgcact tcttgataaa tcgaattgtt taactgcttc aaatatggac
     1681 aatgacggat catttttcaa aacttcttta atttttaagg tttttacaac agattccggt
     1741 aatacatcct cgcgaattaa gtaaaacttt ttataatctt ttttgtccat tttcaagcac
     1801 tcctattcaa cgaattcaaa ttctccacca aggattctaa caatatctcc atttttacat
     1861 ccacgtgctc tcaacgcttc gtcaataccc atagaacgca tttgacgtgc aaatcgacgt
     1921 actgcaggat cactgttaaa gtctgtcatt ttaaacattc tttcgattgc tttaccgctt
     1981 acaacgtacg cagcatcgtc atcacgtgta attgtgaatt tatcttgact aggtgtatgt
     2041 ttgtaaatca ctctattgac acctaaatct tcttcttcat ctttactgaa gtcaatgtct
     2101 tttacttctt ctaatttgtc tgctatagca taaagcagtt catcaatatg gtcatgcata
     2161 aatgtggaaa gtgggataat gtgcagagaa tcatcattca aagcttcttt aaatgcttct
     2221 aaattctctt ctgcattagg catatccatt ttattagcaa ccacaatttg aggtcgctcc
     2281 tctaaacgat gttcgtaggc atttaattct tcattgataa ccttgtagtc ttcataagga
     2341 tcacgacctt cagagccact catatctacc atatgaacaa ttacttttgt gcgttcaacg
     2401 tgttttaaaa attggtgacc taatccaaca ccttcagacg caccttctat caatcctggt
     2461 aagtctgcca tgacaaaact tctttggtct ttcgtagaaa caacaccaag gttaggtttt
     2521 attgttgtaa aatgatatgc gcctatctta ggtttagctt tagatacaat agataataaa
     2581 gtagatttac ctacactagg gaagccaact aaaccaacat cagctagtaa ttttaattct
     2641 aaagtaactt caatttcttc acccggttca ccattttcac tgaaatctgg tgctgggttt
     2701 ctaggagatg cgaaacgaga attaccacga ccgcctcgac cacctttagc cactactgca
     2761 cgttgaccat tttcaactaa atcagctaaa acctcttccg tttcaacact tttaataatc
     2821 gtgccaggtg gtacctttag tacgagttcc tcagcatttt taccatgcat attactactt
     2881 tgaccggcgt cgcctctttt agccttgaaa tgtgtttggt atctaaaatc taataacgtt
     2941 ctcaaacctt catctacttc aaatataata gatgcaccgt cgccaccgtc accacctgcc
     3001 gggccaccga atggaacata tttctctctg cggtatgctg ttataccatt accaccatca
     3061 cctgctttaa gtgatatttt aacttgatcg acaaacatga tttcacctct ttttcttaaa
     3121 atttattttt cttattattc tatacattat atcattatct cattaactag aaaataaaga
     3181 caaaaaataa acaccagaag tgatcacttc tggtgttaac gatgacaaat tactcagctg
     3241 ctgcgtatac agaaacttgt tttttgtcgc gacctttgcg ttcaaattta acaacgccgt
     3301 cgattttagc gaataatgta tcgtcgccac cacgacctac attttcacca ggataaattt
     3361 tagtgccacg ttggcggaat aagattgatc cacctgtaac gtgttgacca tcagcacgtt
     3421 tagctcctaa acgtttagaa actgagtcac gtccgttttt tgtagaacca agtccttttt
     3481 tagatgcgaa gaactgtaaa tttaatttta acattatgat tgcacctcac ttatagttta
     3541 atctgatatt ttctttatat tcttcttcaa ttgtttgcaa tgaaactaac attgcttgaa
     3601 gaattaattg cgcttgttca ttagaagtat caacacttct aacatggaaa tgtccaccgt
     3661 catcattgta atcgatatcg ggcttctcag ttgttaaccc cattatagca ttaacacttc
     3721 caaaaagcac tgcggatgca cctgcacaaa ctatatcatg tccatactcg ccatgttctg
     3781 catggccatc catgataaca tcagtgattt gaccgacatc gttcaatgta atatcaacag
     3841 taatcataat tacgcgttga ttttgtcgat agttaattta gtgtaaggtt gacgatgacc
     3901 ttttttacgt tttgagtctt tacgacgttt atatgtgaat acagtgattt tcttaccgcg
     3961 accttgtttt ttaacagtag cagtaactga agcaccttca actgttggcg caccaacttt
     4021 aactgcgtct ccacctacga ataacacttt gtcaaatgtg aaagaatcac cttcgttaac
     4081 atctaatttc tcaacaaaga tttcttgtcc ttcttctact ttaacttgtt ttccacctgt
     4141 ttcaataata gcaaacatac tttgcacctc ctataattta agtcacgcca aatttaggtg
     4201 acatacatgt tctttaacct aaatccgagc ggttgtatgt agctaaaaac tactcaacta
     4261 ctgcatttta gcattagggt ttcttactgt caatcttcaa ttgtactttt ctaaagaatt
     4321 tagtaataat tggatagaaa ataatgagta atataaaatt aagccctaat gtaggtatta
     4381 atctataaag tacaaattca aataaattaa atgctattaa tcctagtacg ctataaataa
     4441 tagctacata gatttctagg aatattgtac ttaataaaac cacaaagaac aacatcgtat
     4501 agtctctata aaatgtttta aagaaaaagt cttgaattac aacgaacaat atataaccaa
     4561 ataaatacaa cccataaaaa ctaccaaaat ataaatcagt aattaggcct aacacagtag
     4621 ataaaataat agctacacca aaacttctat aaacacatat tattagtaaa tacattagag
     4681 tcaggtgtgg gacaaatata atatctttcg tgccaatttg cattggtata attaacccta
     4741 ttgcagtatc aatataaaat aatacaatac cgataagaaa gtagtataat gcacgcatta
     4801 attatcacca ctttcattat ccggtattgt cttagggtct cttttagcta catatacatg
     4861 atttaaatct gataaattcg ctgctgtttt cactcttact tcttttgata agccgtattc
     4921 atcattttct acttttgaaa cttcacctat gtaaatgcta cttggtaatt gatcagctaa
     4981 accacttgta acaactttat ctcctttttt cacactatcc ttgttattaa tatcagtaat
     5041 aattaattct tcgtttttag aatcataatg atcgattaat ccaaaaacat ttttatcatc
     5101 atgttggata ttaactgata aacgattagc gcgtgtgttt gttgaaatca aatctacttg
     5161 tgatgaaaat tgatttactt tagagattcg acctactaga ccttctgaag tcatcacggc
     5221 catattattt tctattccat ctttagcacc ttgattaata actaatgtat tcatccattg
     5281 gtctggattt ctagataaca ccgtactaga aattggttcg aatttagata tgtcttctat
     5341 atccagttct tttttatact ttttattctc tgatttcagt ctttcgtttt cagcttctaa
     5401 ttgcttaacc ttactgtttt gttctttcga actatctttc gcaaaaaggt tattgattga
     5461 acctgttacg aaatgaacag gataactaac cgccctttga ccgaatgcaa ctgaatctcc
     5521 tacgtattgt tctactggtg attgtgattg cgaacgtaaa gatacaccaa ttaaggcaat
     5581 aaacacaatg attgcacata aaataacaat caacttgttg tttttaaaaa actttgacaa
     5641 cctaaacacc tctattaccc gactatttta ctactttata tcattttata ttactcgtag
     5701 attgaaataa agtggtaacc ttattattcg caaataaaat tctaaacccc tatttaatat
     5761 aaagaacgct agaaaaatca tgctaaaatt ctactttaaa acataaaatg taatgttaat
     5821 ttgtattata acaagtttca aaccaaatag tgcattaaag tctcgttttt ttaaaaattt
     5881 taaattcaaa aatatatatt agctaaattt gttttccact aaaagaacaa tttccaaaat
     5941 aagattatta aatagctatt tactatatcg taaatattat attgccgtaa cattcgcttt
     6001 cttaaatttt tgttctgaat acaaactatg aatggcttta tttaatatca actttttgta
     6061 tattatcatt ttgtacacaa ccaaaaaaac attttagaat gatatgatgt agcgccacga
     6121 tgatgtttga attattcatc gaattcattt tcaaggattg tttcaacgat tttattaaca
     6181 tgtcgtgaca tatcacttgt cgggataaga actgaagttt ccattggtag tgtaagttga
     6241 gtcatattat aatctttata tataaggcac ctcgttaatt taatttagta gtgtttatta
     6301 aattatacgt aagggcctta ttttcaaaag tattttaatg taaaattaca tataaatacg
     6361 aagtattttg gcgagaccct tgaggaacga gccaaaaaga agcactcaga tgatttaatt
     6421 caattcatct gagtgctatt cttctgggat ttgtctccca gtctctttcg atataatttt
     6481 tataataaat agaatagaac ttacgctatc taccattaca atttttaaat tgagactttt
     6541 aaatataaag tggtcataca tcactaagga gccaggctta cagtttcaat taattaaaaa
     6601 tcatgtatta gaaacttctt aacacccatt tagtaccaat gaaaatatag ctatttttct
     6661 tcttcgtcac ttgtttcact agatttttca gcttcttttt cagcctcttt ttcgtcttct
     6721 ttatataaag tttcttcttt acgccaacgt gcgaataaat tttgtgcttt tgcttgttca
     6781 tctacttttt tatctttaga ctgttcactc ataattagac accaaccttt tacgttttta
     6841 cttatataag gctaacgcat tttagctgag aattcaaacc acttactcgt aattagatgg
     6901 tggttgcaat tcgatatgtt ccccaagttg attcaggtct tgttccatct ctatttctgt
     6961 tttataaaca cgaatagagt ctgagccaaa tttataaata ataaattcat caccacgttg
     7021 acctgctaaa tatttatcac tataccccat tctaccaata cctgatacag acataaattc
     7081 tttcttatct atccaatcaa atacattctt agcctgacta cgaggcacat tttttaatat
     7141 atcattatct tctacagaat aacgttgacc gcctgttaaa tcaccttctg tttgcatgtt
     7201 gctagtaggt ggctcgttat tatgcactgg gttccattgt tggtctttta aaaacggcgc
     7261 atatttcaat gcgaagaaaa caatgactat aatggctata atagctataa aatttttaat
     7321 aatactaaaa ataaaccgca tgaaccaccc tcctataatt cactctatat tataaaatca
     7381 attaatttaa atatcatcag tctgtagtag tattcaaaag ttaaccatag actgatgcat
     7441 acgtgcttta ttcatagtac aattatgtac aaagggagtg aaatataatt atgagtatta
     7501 tatctataat cctacttgcc ctcttagtta tattattatt tagagtaggt ttatcaattt
     7561 taagattttt aatatacgtt ggaattatcg tactttgtat atatctaggt tatcaaggta
     7621 ttctttggat aatggagaac tttaatagtt actttagttt tatataaatc agagtataaa
     7681 gaacacaatc tatgcatgtt atcacaggta taaatcattc cagtagctga taagattctt
     7741 acttaaatat acatttttat ttttttgtaa ggattttacc tgcttttatg acggagaaag
     7801 aagtcaaaag ttagatttga cttctttctc cgttcttttt gatctcgttg tgctcacaca
     7861 taattttact ataaccataa tatacaaatt aatgcttccc aaacgttata cctatttttt
     7921 aacattgttt gataacactt gataaaaata ataacatcca cacaatagta gcgcccatat
     7981 aattgcgata attaatgccc cgattaagta taaccaaaaa gaggtatgat tcgtattaaa
     8041 aataaagaat aacatagtag ttaataaaat ccctacaatt gaaatgatta ctgttttttt
     8101 agtgctttta aagtctatag gtttttgatt tttaactaac tgcattaaat aaattacagg
     8161 cagcaataag ccaatcaata atattgttcc cacttcacaa cgcctcctta attaacaact
     8221 cgattatacc gtaagtaatc aattccagaa agctaaaatt aagtggaacg cgtattataa
     8281 taagaagttt atactataca tgtatatatc tccaaataaa gaactacagg catttagact
     8341 taatcaaaat acccttcctc taccatgctc agatatgcat gatccccaat aataatatgg
     8401 tctagtacat ctatcccaag aattactcca cattctctta gtctatcagt tgttctaata
     8461 tcttctttag atggcgtagt gtcaccagac gggtggttat gtaatactac aatggcgtta
     8521 ctagcgcatt ttactgcttc gctaaaaatt tctctagggt gaacaattga tgaatttaat
     8581 gtcccaataa atatcgtttt ctgcttgata attacatttt tagaattaag aaataatgca
     8641 ataaattttt cttgagttaa atgttccatt ttacccatca taaaattagc aacatcttga
     8701 gggctagtaa tttgtatttt ttcttctaaa ctacctgaat gcatgcgttc tccaagctca
     8761 aatgctgctt ttagaattaa tgctttatac aaaccaattc ccttcacttt atttaaatca
     8821 ttaatagata atgcctttaa ctgttttaaa gtttctactg atttcaataa ttcattagct
     8881 atatctaaac ttgaacatcc tttcctacca gtattaatta aaatagctaa taattcagca
     8941 tcagataaat gggttgggcc attgtttagc aacctttctc taggtttttg attattggcc
     9001 agttctttta tcttcataac taaaaacctc caaagacaaa attttgatat gttaatagtg
     9061 ttatattaaa tgcgagataa ataaaaggaa taagcggaat ttttgaactt tcattatgaa
     9121 atacaagtaa tatgaacaag gcaaaaagac cgccacagat aaatgtaaat aaaagtatga
     9181 ttgaaaattc aatagaaggc aaagctaatg ctagcaaaga gaaaataatt atatcaccat
     9241 aaccaatggc attatgaaat agtatataaa atacatgaag taaacttgtt acgaagagaa
     9301 atgacatgat gtgaagagga gtaataaaac aaatacaaat agcaaaaacg actatcacat
     9361 gcaatggaac tgtgtatgtc ttaagatcat atatagctaa gacgagtaga aataaataaa
     9421 ttaatagtaa agtagcgtta tcaattaaat tatgaggtac ataaaatatg taaaagagag
     9481 gaatcaaaga gagtaactca ccaatcaagt aaaaaatatt tatttttcga ttacaacaac
     9541 ttgaagtacc tcttaaaaaa ataaagctta aaaccggtat caattccaaa agtcttattt
     9601 ctttgagaca atcatcacac cttgaacgga gtgtgagata acttaattcc agcttttcta
     9661 caaaacatag ttgatataaa aaactaaaca atataggata aattaaaagt agcgttacca
     9721 acacttcacc tcctaataag cattatagca ccaatcgata aaaccaataa gaaaaataac
     9781 aataattaaa taatttcaac aacacttacc taacaaagca aattttgtaa ttagcgttaa
     9841 tattttaatc atcatatgtt agttcatttg tgaattatat gttcgaataa taaaaccagc
     9901 tcgaaaattt aatgagctgg ttttatatgt ataaagctga tattggtatt taattttgta
     9961 acgttaataa aatttaacta ttcaaaaaca ttgttagcat ctaatctttt tgaatttcat
    10021 ctacagtttc ttcaacttct tttctagata tcttctctct accatttttc attgctttaa
    10081 gtgatttatg agcaagtgct aatggcaaac gacaaaatag taaaattgtt tttttattaa
    10141 tgtctttcat atatgcatcc gcttttgcta aattatcttc tgcgtaatta aacaaatcat
    10201 ctcgtgtcca atcatcaggc ataaaactaa ctccacgttc tgcaaaatct tcttgttcat
    10261 ttctaagaat attgacagct tgtaagcctc gtccatatcc aatagccaat tctctatctg
    10321 ttttaacatt tgcacataaa tcccataatt gtgagagcat gacaccgaca aggcccgcta
    10381 cgtaatatgt ataatcatct aaatcatctt tggtatgaat gtcccaattt gctttcgccc
    10441 atttcgccat accaaaagcc atttcgctag aagcatctaa tacaattggc aatgtcttac
    10501 taggacaagc ttctatccac tcacctaatc ttaaagtaac ttcaggcatt ttacttttta
    10561 ctggttcaag aatttgcatg tattttactt catcaaatgg cgctttaaat aactcgctca
    10621 cttgcatcag tattgaatgt tttaaaccgt tatctaattc ctcatgatct tcaatttcat
    10681 caatagctct taatactaaa taggcagatg ctactgtatg ttttaattct ttttccaaaa
    10741 aagttatcgg aatataaaaa gtgcgacttg tttcttttaa aacacgcatt gcatcttttg
    10801 ggaatttctt ttcagtcatt ttaatctaat acctcccctt ttttaaatat tatcatacaa
    10861 ttacaaaata aaataggaaa tgcgcatcac taaagttaat ggaatttctc tcgtcaaaaa
    10921 attgtcaaag agccaatttt tcaaactaac ttttagctct tggttataac tatatttagt
    10981 tatcactttt cttttatttg aaacaaaaat aagcgaacgg tcaataaact gttaaaccgt
    11041 tcgcttattt aataaaaatt ttatatttaa ctgaaatcga ctttagcttt tacttcactt
    11101 ataaaataca agcttccagt aatgattaaa ccatcaccat tataagattc gataaatttc
    11161 acataatcgt caacaagtgc tttttggtca aatcgaactt catcaaagat tgcttctttt
    11221 gttaaagctt tcggaaaatc aaaatctgtt atatagaatg tagaagcaat cgttttaagt
    11281 tgatcaacca tagcatttaa aggtttacct ttgattgcag aaaataaaat atcaatattt
    11341 tcagtgtgat aataattttt cattgtactt attaatgctt ctacactttc aacgttatgc
    11401 gcgccatcga caatcatcaa cggacgttct ttcacttgtt ctatccggcc tgtccaactc
    11461 actgactcaa taccatcaat cattttattg aaatctaaat caacgatgtc tgactcattt
    11521 aattcgatga gtgcggtaat tgctaacgcg gcattttctt tttgatgttc acctaacata
    11581 tttaataaaa gcgtctcaag ttcataatct ttatagcgat aagtgaattc ttcatcttcg
    11641 gatataatac taatatctct atccaactca ataccttcag cattttgttg ttcaacataa
    11701 tcgcgaataa ctttgagtgc ttcttcattt tttacagcat aaatgatagg tgtgttcggt
    11761 tttacaatcg cacctttatc ttttgcaata tctacatatg tgtcacccaa tatatcagta
    11821 tggtctaaac ctatacttgt taatatagat aagattggtt taaaaacatt agtagaatcg
    11881 tttttaatac ctaatcccgc ttcaataatt acaaagtcaa ctgggtggat ttcaccaaaa
    11941 tataaaaaca tcatagttgt aataatctca aattcggttg cagttccaag gtcagtttcc
    12001 acttctaagg cttcgcttac tggttttact ttttgaacta atttaacaat atcatcatca
    12061 cttattggca caccattcaa gctaatacgt tcgttgaacg tttcaataaa tggcgatgtg
    12121 aaagtcccta cttcatatcc gttatcaaca agtgctgaac gtagatatga caccgtggat
    12181 cctttaccat ttgtaccacc aacgtgaata ccatttatat taaattgagg attgttcagt
    12241 ctatctaaca tccactccat acgtttgacg ccaggtttaa tgccaaattt agttcgttca
    12301 tgtatccaat ataagctatc taggtaattc atcttaagga ctcctatgct tttaattgat
    12361 taattcgtaa ttttacacca tcatattttt cttgatacgt ttgttttttc tcacgttctt
    12421 cattaataac tttttcaggt gctttattga caaagttttc atttgctaat ttcttattca
    12481 cgcgatcaag ctctttttcc catttcaaga gttcattctc taaacgctca atttctttat
    12541 ccatatctat tagaccttct aatggtaaca caacttcacc agcagtcgta acagaagtca
    12601 tagctttttc aggaatttca atatctgtat caattgtcaa ttcgcttgga tgacagaatc
    12661 tatcaatata atttgagttg tttaacagtg tatctttaat attgtcatct ttcgctttaa
    12721 tgaagattgg aattgctttt gacagaggcg tatctacttc aaggcgtgat tgtcttactg
    12781 atttaataat ttcaacgagt tgttgcatcg tttctttact gtcatcaaaa gtaagagcat
    12841 cattcacttt tggccaagat gcatttacga ttgtttcacc ttcatgaggt agattttgcc
    12901 aaatttgctc tgtaacaaat ggcataaatg gatgtaacat tctcattgta ttatcgagaa
    12961 catacgtaag cactgaacgt gtaacttgtt tttgcgcttc atcttcacca ttcataggta
    13021 tcttactcat ctcaatatac caatcacaga attcatccca aatgaagtta taaagagtac
    13081 gcccaacctc accaaattca tatttatcac ttaaatcagt aacattagca atggtttcat
    13141 ttaatcgagt taaaatccat ttatctgcaa gagaaaggtt acctgataaa tctacttctt
    13201 ctaccttaaa gtcttcacca atattcatga tactaaatct cgcagcattc catattttgt
    13261 taatgaaatt ccatacagat tcaacttttt ccgtagaata gcgtaagtca tgaccaggcg
    13321 atgaaccagt agctaggaag tatcttaaac tatctgcacc atactcatca atgacatcca
    13381 taggatccac accattacct agtgatttac tcatttttct accgtcttct gccctaacta
    13441 atccatgtaa tagtacatca ttgaaaggac gtttaccagt aaattctaaa ccttggaata
    13501 tcattctcgc aacccagaag aaaataatgt catacccagt cactaatgca ttagttggga
    13561 agtaacgttg aaagtcttca gcttccgtgt ctggccaacc taacgtagaa aatggccata
    13621 acgcacttga gaaccatgta tctaatacat cttcatcttg ggtccaattt tcaatatctt
    13681 caggtgctga ttcacctaca tatatttcac ccgtttcttt atgataccaa gctggaattt
    13741 gatgtcccca ccaaagttga cgtgatattg tccaatctct aatttcttcc atccaacgat
    13801 taaaagtttt ttcaaaacgt gcaggaacaa aatcaattct atcgtctgtt ttttgattat
    13861 ctagtgcttg ttcagcaagt ggtttcattt taacaaacca ttgcgttgat aaatatggtt
    13921 ctacaactgc accagaacgc tctgaatgac ctactgaatg ctcatgagcc tcaattttaa
    13981 taacaaggtc ttcagcttct aaatctttaa ctaattgttc acgacaatca aatcgatcca
    14041 tgccttgata tttgccagct ttatcattca ttttgcctgc ttcatccatt acgataatac
    14101 gttctaaatc atgacgattt ccaatttcaa agtcattagg gtcatgtgct ggtgttactt
    14161 tcattgcacc actaccaaat tcaatatcaa catattcatc tgctaatata ggtagttctc
    14221 taccaagaat aggtaaaata accttcttgc ctataacatc tttataacgc tcatcattag
    14281 gatttacaac aattgcagta tcacctaaca ttgtttcagg acgtgttgta gcaatttcaa
    14341 taaatccatc accatctgca tatggatatt taaaatgata aaacttacct tcaacatctt
    14401 catgtattac ctcaatgtca gataaagcag tacgtgcgat tggatcccaa tttataatat
    14461 attcaccgcg gtatatcaag cctttgttat acatatcaac gaatactttt ttcacagctt
    14521 tacttaaacc ttcatctaac gtgaaacgtt ctctactata atctaaacct aggccaagtt
    14581 ttgcccactg ttctctgata aaagtagcgt attcctcttt ccaatcccaa gcttgttcaa
    14641 ggaatttttc tcgacctaaa tcatgtcgtg ataaaccttg ttcgtttaat tttgcttcaa
    14701 ctttcgcttg cgtagcaatg cctgcatggt ccataccagg taaatataaa gtatcgtaac
    14761 cttgcatacg tttcattcgt gtcaatatat cttgtaatgt cgtatcccac gcatgcccta
    14821 aatgtaattt accagttaca ttcggtggtg gaattacaat tgtatatgtc tcttttgaac
    14881 tatcttcttt tgctttaaag taaccattat taacccattg gtcataacgt ccggactcga
    14941 cttcgttcgg attatatttt ggtttcattt ccatacgtta aaatcctcct taaaaataaa
    15001 aatacccgcc ctatcaatat aggacggata ttccgtggta ccacctaaat tcaagaaatt
    15061 ataaatgtaa tttcaagcac ttaattatat gattaacgct caaacacgct ttagcctata
    15121 ctataattat ttaagaatta tatttcagct aaagttcaat gtgggctacc ttcaataagt
    15181 taaattatac atttacacca accatgtact ctcttataaa tttcagctta tttactcttc
    15241 ccagtagaca atattctttt acttaattat agtataatgg atgttaaaat aagtcaatgc
    15301 actggagtga aatttatgaa tgaatgcgca tttggaacca aagatccact atacctccac
    15361 tatcacgatg aggaatgggg acaaccaatt tatgatagtt tgaaattatt taaattaatt
    15421 gcacttgaat cccaacatgc tggtctttca tggttaacta ttttaaagaa aaaagaatct
    15481 tatgaacaag cattttacaa ttttgatcca attaaaattt caaaaatgac aactgacgat
    15541 attgaacgct taatgacttt tcccaatatc gtacataatc ggaaaaagat agaagcaatt
    15601 gttagccaag cacaaggtta tttcgatata gaaaaggatt atggaagctt tagtgacttt
    15661 ttatggtcct tcgtagatca taaaccaatt gattgtggct atactatggc aagtgatcgc
    15721 attactgtcg atgaacgtgc tactgaactg tcaaagcagc ttaaaaaata tggctttaaa
    15781 tttttaggtc ctgttactgt tttttctttt ttagaagctg caggtctata caacgcacat
    15841 cttcaaagtt gtccgaataa tcctaaagta tataacggaa aaggtttcga ttaaatactt
    15901 tgcgaaaatc ttaatagaca accttactat taagattttc caatacacta cttatataat
    15961 tgaaaatacg ttctatactt atcatttata gataaaacca cagcaaaccc atagtgttta
    16021 ctgtggtttt attatatttc atcgtaattt ttaaaatttc ttattaatag aatctttcgc
    16081 tactctgtat tttaggaaat aacttagtaa aggagcaatt aggaatagta tgaagaatat
    16141 tctaaagatg tgataacttg aaatcaatgc tacatctgca ccagtttcaa ttgcaactaa
    16201 cacgatttga ctcataccgc ctggcgcagc acctaaaaat aattcattaa cagaatggtc
    16261 ggaaaccatt gcaataagta acaccattac aaaagtcagt aatattaata gtatattttg
    16321 aaatgcaatt gctacagcaa ttctaccttt catttggtct aataatttag caatttgtat
    16381 accaatacgt atcatataaa taacttgtgc tgccgcaata atataattgt ctaaggtaaa
    16441 tgtaacgcca gttaataaat tccaacagat aagtactaat atcggtgcaa gtaattgtct
    16501 ggtcggaaaa ttaattttcc ccataatgac atatactaaa aatactgcaa gtgctaataa
    16561 aagtatattg ggaatagtca atgcttcggt tagtgtattg actacactat cctttgcaga
    16621 acgattatcg ccactgcctt gaaagaaata cgaaataaat ggtacaagaa taacaacaaa
    16681 tataattctt gatgtttgcg ttaaactgac taccataata ttcgctttct tattttcctc
    16741 tgccattata agcatttgac ttaacgcacc tggaatcacg cttaaaattg cagtttcagt
    16801 atttacgtta gcaatttttt taaagaaaaa ggctattatt aatgcaagcc ctaatagcat
    16861 aactgtgatt aatataatag tcagccaatc atctttgata tcaaatatta cattttcagt
    16921 aaaagttgat cctatttgga cacctaataa taccaaccca atttgactta gccaaaacgg
    16981 ccattcaact tccatgtgaa agcatctaac acaaatgaca ctggcaatta taggtccaaa
    17041 cataaatggt aacaatatat ttgctgaatt taagattaga cttaataaaa tagctagcga
    17101 taaaacgatg atattatttc ttaattgctt actcatgttc tcacaacttt catagttatc
    17161 gtcatactta actgagctat ccatattaaa acccgatcaa cgctatggtt gttcgggcat
    17221 aatttaagct ttatacaatt cgacttagag cagtatcgaa cgcttctatt gtttgtttaa
    17281 tatcttcttc ggtgtgcgct gttgagagga acgtgccttc aaactgtgaa ggtggtaaaa
    17341 acacgccctc attagccatt tctctgtaca tttggctaaa catttctaaa tcactattgt
    17401 ttgcttcttc aaaatttgta acaggccctt cattcaagaa atatcctatc atagaacctg
    17461 ctcgatttac agtgattggc acattatgtt ttgtaaacac tgcttttaat cctgcttcta
    17521 attggtcacc taatttatta aaataatcat atgtttctgg tttaagttgc actaatgttt
    17581 cataaccact agtcatagct aatgggttac ctgataaagt accggcttga taaatatcgc
    17641 ctgcaggtgc aatatgatcc atgatttctt ttttaccacc aaaagcgcct actggtaatc
    17701 caccgccgat tactttacct aaacaagtta aatctggtgt cacatcaaag tacccttgtg
    17761 cgcagttata acctactcta aaacctgtca taacttcatc aaaaatcaat aatgagtcat
    17821 atttagtggt aatatctctt aaaccttgta aaaagccttc gaccggtgga acgacaccca
    17881 tattacctgc aacaggttct acaataacgc ctgcgatatc gtcgccaaat tcttcaaatg
    17941 caactttaat tgcctctaaa tcattataag gcacagtaat tgtattttta gcaatacctt
    18001 cagggacacc tggagaatct ggtaaaccta aagttgcaac gcccgaacca gctttaatta
    18061 gtaaagaatc actatggccg tgataacaac caataaattt aataatttta ttttttccag
    18121 tatagccgcg agctaaacgc aaggtatcta atgttgcttc tgtaccagat gaaaccatac
    18181 gtactttttc gattgatggc acacgatcta taacaagttc tgctaatttg ttttccaatg
    18241 ttgtagacgc accaaaactt gtacctttat caactgcttc atgaatttta tcaataactt
    18301 gcttattttt atgacctaaa attaacggtc cccaactcaa tacataatca atgtaagcat
    18361 tgccatcaat atcatatatt cttgaacctt caccatgatc cataaaaatc gctggcgtat
    18421 ctacagattt aaaagctcta actggactat ttacgcctcc aggcattaaa tgttgagctt
    18481 tttccattgc tttttcagaa ttactataac gcattttatt catcctccta ttgttcttca
    18541 tctatatatc gacaaatgtc ttttgagaaa taagtaataa tcatatctgc acccgcgcgt
    18601 ttcatagaaa tcatttgttc catgactaca gccttttcgt ctatccaccc gttaattgcc
    18661 gcagctttag tcatgctgta ttcaccgctt acattatatg caacaacagg aacatttgtt
    18721 gtatttctaa cgtctctaat aatatctaaa aagcttaatg caggcttaac aatcatcata
    18781 tctgcacctt catttaaatc actatcaagt tctcttaaag cttctctacg gtttgctgga
    18841 tccatttgat atgttttgcg atcgccaaat tgtggtgcag attcagctgc atcacggaat
    18901 ggcccgaaga aactcgatga atatttaata ccataactca taataggtac attatgataa
    18961 cctgctttat ctaagccttc acgaatctct gctacaaagc catccatcat attacttggg
    19021 gcaataatat cagctcctgc ttcaacttga gaaattgctg tttttactaa taaaggcaat
    19081 gatttatcat tgtcgacatc tttcgtttct tcattgataa caccacagtg tccgtggtct
    19141 gtatactcac atagacaagt atctgctaca atcaataaat cactgtacat tgatttggct
    19201 tttctagtcg cttcttgtat tataccgtta tggtcataag cgccagtacc tacagcatct
    19261 ttttcatttg gtacaccgaa aaacataatg cctctgatac ctaaatcata agcttcttta
    19321 atttcatcac ctagtagatt caaacttatt tgatatatgc ctggcattga tttaatttcc
    19381 tctttaacat tatcacgttc tacaacaaaa ataggataaa ttaaatcttc ttttcttata
    19441 tgtgtttcac gcaccatact tctcattgat ttactactac gtaatcttct atgtctatca
    19501 aattgcattt gtttcccaac tttctattat tttgttaact aatgattcaa gtgtttgaat
    19561 ttctgatact gtaccttttg catcatattc atataaagtc tccaatgttt gcaatccaat
    19621 tacgaaataa tgctcaaagt tcactggttc ttcatgatta aaaaagtaac gtacagccga
    19681 agagcttgca aaagctacag catcgatttc atttttttta atcatcattt taacttcaca
    19741 gatattatca gtatgtggaa ctggtttata caagtcaatt ttctgaacta tatatttttg
    19801 gttatgcaat tcatcttgta ataacgacct cgccgcacta cttgaaggca acaatatttt
    19861 acttccttca ccagcacaaa acgattcgag aaacccttct tgtgaatagt ctttagggca
    19921 aaacgacacc ttcaaaccta gcgatttaca gtagtctgcg gttttctcac ctataactgc
    19981 tattttatcc actttaacac gtgttagata tggttgaaaa aacttcaccg catttttgga
    20041 cgaaaaaata agccagtcat agttcacatt caataaattt aaatcgaatg ataatggctg
    20101 tacacgaata aacggtctgt gtaagataca agcatcattt cttttaaatt cactggtttg
    20161 tgtcataact ataactggtc tcattatttt cacctcgaag gattattgtt cttcgtttag
    20221 tgctttaatt atttcataag cgccttgcgc atttaatact tcagtaactt tttcaccgag
    20281 ctcaactgga tttgtacctc gctctgtgtg ttcgtaacgt tctttgccat caggcgacat
    20341 aattaatccg gtaaactcaa ttgtaccatc actctcttta gttgcatagc caccgatagg
    20401 cacttggcaa ctaccgttca tacgtgttaa aaatgttctt tcagcagtca cacacgacgc
    20461 aacatcacta ttgtgcactt tgcttaacaa atctagtaat tctttgtcat ctgaacgaca
    20521 ttcaatccct aacgcacctt gcccaattgc aggaattaac gtttctttat ctaggtaagt
    20581 cgtgacgata tcatcagacc accccatacg tctaagacca gcagcagcaa gaataatggc
    20641 atcatagtct tcattttcta atttacttaa ccttgtatca atattacctc gaatccattt
    20701 aatttgtaaa ttaggatatt ttgcaagaat ttgtgcacca cgacgcaatg aactagtacc
    20761 tacaatacta ttgtcaggaa gttcgtgcaa tttaacgtga ttttttgcta tataggcat
//
