LOCUS       NZ_CP021707            20903 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. S063 chromosome, complete genome.
ACCESSION   NZ_CP021707
VERSION     NZ_CP021707.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S063
  ORGANISM  Streptomyces sp. S063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Complete genome sequence of Streptomyces sp. S063, a producer of
            anti-complement compounds and various secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAY-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:19:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,905
            CDSs (total)                      :: 6,817
            Genes (coding)                    :: 6,244
            CDSs (with protein)               :: 6,244
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 574
            CDSs (without protein)            :: 573
            Pseudo Genes (ambiguous residues) :: 0 of 574
            Pseudo Genes (frameshifted)       :: 432 of 574
            Pseudo Genes (incomplete)         :: 192 of 574
            Pseudo Genes (internal stop)      :: 13 of 574
            Pseudo Genes (multiple problems)  :: 61 of 574
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7533178
            Orig. end                         :: 7554081
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021707.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Xinqing Zhao, Life Science
            and Biotechnology, Shanghai Jiaotong University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20903
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="30"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20903
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20903
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10903](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10903)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    354..369
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: medium, score: 24.49"
                     /tool="antismash"
     misc_feature    complement(886..901)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    987..1002
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            1039..2430
                     /locus_tag="CCZ36_RS34210"
     CDS             1039..2430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737568.1"
                     /locus_tag="CCZ36_RS34210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sporulation protein"
                     /protein_id="WP_128819339.1"
                     /transl_table=11
                     /translation="MASTTRRTRPPNADLARLIEASGASHKSLALRVNQLAHAAGIETD
                     YSHTSVANWCKRGMTPKWPVPKLLSQAISERLGRPVSLGEIGMGEAETIDASVGLDFPR
                     DPADAVRVATSFWSSVNRRDFLAGSGFAASAFTTPVTRWLVTPADETADHAGGKQVGRA
                     DLAELRDAADDARRWDSKYGGGNWKANSVTDCLDHRAGPLLQGSFSDDIGRELFSVTAE
                     LSRLAGWTAFDVGEHDAAQRHFIQALRLARAGGDVQLGCYVLTTMAMQSLMRGFASEAV
                     DMAQGAFNRAKGQAVPRVLAFTKLIEARAHARENDPTAASRALKASEDLLGQAKDDSGD
                     EPAWIDFYHHARLSADAAEIFRDLKNPKAALTWNQQATAMPTGVFTRSVGMRLAIVGTA
                     HLQARDLDHGLELGNRSVDILARVQSSRAKDYVREFNTALAPWRREPAVREFVQRSRKE
                     LGVAA"
     misc_feature    complement(2530..2544)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.58"
                     /tool="antismash"
     gene            2593..3400
                     /locus_tag="CCZ36_RS34215"
     CDS             join(2593..2930,2929..3400)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="CCZ36_RS34215"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_164873592.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MRADLVPDDLWERVAPLLPPAPERRHRHPGRLRVPDRVALAGVIY
                     VLRTGVAWRDVPAEAVGCSGVTAWRRLRDWTEAGVWPRLHAALLTELRRASLLDLDDCS
                     VDGSHVRAPRKGDHVGPSPVERARSGSKHHLIVDRHGTPLAVTLTGGNRHDVTQLLPLL
                     DAVPSIRGLRGRPRRKPRRLYADRGYDFDKYRRLLWKRGIKPMIARRGFAHGSGLGKVR
                     WVVERAFAWLHQFKRLRTRYERRADLHQGLLELACSLICLRRLRTSS"
     gene            complement(3406..3810)
                     /locus_tag="CCZ36_RS34220"
     CDS             complement(3406..3810)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140620.1"
                     /locus_tag="CCZ36_RS34220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128819340.1"
                     /transl_table=11
                     /translation="MERVGDARGLVLGYVDALNAVDAAMRAAIPSLERLADVLGLVRSH
                     RIINRSGRVGTYSYSVHGAGCRFVSDDGIEVDVDFAPDGSEIFDLWRLRWYGLSLPEPL
                     DVTDQDLRTAVRSLQPLLTEVRPGWFSVAS"
     gene            4119..4925
                     /locus_tag="CCZ36_RS36735"
                     /pseudo=""
     CDS             4119..4925
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031871.1"
                     /locus_tag="CCZ36_RS36735"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPLRSRPYPSDLSDARWKLLEPTLTAWRTERRGKGRDIGRPPEHD
                     LRRIMDAILYVDRTGIPWRYLPHDFAPWETVYGYFAAWQKDGVFDQLNGLLRAWSVRLR
                     AAMSSPAPAFSTPRASRPRPTCRRSARATTRARRSRAANVT"
     gene            complement(5471..6547)
                     /locus_tag="CCZ36_RS34235"
     CDS             complement(5471..6547)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552717.1"
                     /locus_tag="CCZ36_RS34235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_237302800.1"
                     /transl_table=11
                     /translation="MADLLENREIDGINALFRTIGTLKPDTDLSRLPDRLAQFLREAST
                     PPPDWSEADVKAAEGFFGHHHGTASMLQGTVGLIGTYLAPTGAFTLRSTGRLGGVEGPG
                     RRLSQSSRLFIDMGNKNAMRDGTLAATVTKVRLVHASVRQLHKQSGQWDYDKWGEPVSQ
                     KYTTGAACIFSTQILQGMRNLGIDVSADDARGFMCAWHYVNHYLGTPEKWQLPKDANEA
                     ERLWNQERDKEWQKTDDGVFMTAQAIKFYRDLLKPGASDAYIALTRVALTDKYADMAGL
                     PKSPLDLAGKPLAAGHGLVSGTAGGLFGGATQRTVGVNPYKDLLGVASKAFNEIEQYAL
                     THDQDDQPQMHQELDDNR"
     misc_feature    6532..6546
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(7142..7156)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.04"
                     /tool="antismash"
     misc_feature    complement(7637..7650)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    7658..7671
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            8371..10017
                     /locus_tag="CCZ36_RS34245"
     CDS             8371..10017
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174259.1"
                     /locus_tag="CCZ36_RS34245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_237302801.1"
                     /transl_table=11
                     /translation="MAGLTAAMELAERGFEVTVVEPAGWGGKARSAWVAGTGRGGRLDL
                     PSEHGFRFFPGFYRSLPDTLRRIPVDGSAEGVAGNLREATQMLSARSGRVGERVTDVSV
                     AAGARTPMEFLRAVGLEAGGRGLTSEELLYFANRMLVYMTSSDERRLGQWESTSWWDFA
                     AADGASEEYIKACVVGATRTVVAARAEVCSAHTVGGFLEAFSYGFLGRGEELQPADRVL
                     NGPTSTAWIDPWIRHLASLGVRLKLGWGVERLALSGRRVTKAQLRGPHGQRRELEADWY
                     VCALPVHRIGALLDRGLAEADAELKSVTGLHTDWMVGMQFYLTQPVPVTHGHVLFLDSP
                     WALTSISQAQFWDGDFPATYGDGTVADCLSVDISSWDTPGILYGKPARECSRAQIAAEV
                     WAQLCDGLNGAGRTRLHEGLLHTWELDPAVRNLDGPGPAVNDEPLLINTTGSWAARPRA
                     VTAAANLFMAGDYVRSPVNLATMEGANQAARIAVNALLEAAGGAGVPAAVHALHQPGEL
                     RRLKEVDAELFGQGRAHIMDGLPPWKVSARV"
     gene            complement(10001..10903)
                     /locus_tag="CCZ36_RS34250"
     CDS             complement(10001..10903)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="CCZ36_RS34250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_206515790.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9e-63, bitscore:
                     210.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAYQFGWSGEGARQGGKYVRAALTLACARAVGGADRPAVPAAAA
                     VEMVHNLSLLYDDVLDGDTMRRHRPAAWQVFGPSSAARSADAMMLTAFDVLSEADGPDG
                     PVAREASAALVDVLIQLAVGESLDLVFEGRTQVTLAECLEMVSGKTASLFACACRLGAL
                     YGGADPAVCAQWAEFGHDLGMAFQLVDDLLGIWGDPAVTGKPVFNDLKNRKMSVPVVAA
                     LGSGTPAGDELARLYAQPGSDTADLARLVEEAGGRAWTSDRAAQHATAARDRLHRLTAL
                     PSALEDLEALCTVVIRRVH"
     misc_feature    10946..10958
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    complement(11011..11031)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     gene            11234..12226
                     /locus_tag="CCZ36_RS34255"
     CDS             11234..12226
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CCZ36_RS34255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237302802.1"
                     /transl_table=11
                     /translation="MIRRLRRCGHAPGAISPEDQAVVDEFRAMLTALRNPEPWTPGTGS
                     ARDIAVRVGPFVERAHTRPGDDHGPDLIAVTLVHPDTPHAGAYLHGRQLGYTEHDWLRC
                     PTTSIVGYWQPGYTQLTHAANGLHLPDDIGMAPANYALYIEARKRDDSHDGHTLLRLGP
                     YTQPRHAQQDGDRLTAALNGRETTLVPGYRITMRFGPLNVSDHQLFTAPHEADAVSLLD
                     AEADKGSPRLPACVGSGLLLSAQPPWDRSSAYARQGLKPRRPHTASSALPKQAPHLAIR
                     EGESGQSHLPLYSSQSQFVRRAQRWSRMLLLPPKDVVGQLLPLVRLGRS"
     misc_feature    complement(12843..12862)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.99"
                     /tool="antismash"
     gene            13082..13735
                     /locus_tag="CCZ36_RS34260"
     CDS             13082..13735
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CCZ36_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164873593.1"
                     /transl_table=11
                     /translation="MTKGHARKREVRRRMKEEGQSYQATLREQLQDGSDASPDLPNADS
                     REDYIDAVWDADLPQMVKVLLYELASRLDLTVPDWRTNSHHVRFEEEELARAVGLDVEA
                     ANLCRDLALEANWLVEVDEEMVELREPHQDWDLFAGALRDHKEPIVDRVVYRSRLAAFD
                     SETKRLRTDPIMSIRRLRAGMAAVIGHTFVPKCVGGPFTQDTVGLGSGQCSDQP"
     gene            complement(13897..14889)
                     /locus_tag="CCZ36_RS34265"
     CDS             complement(13897..14889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063842.1"
                     /locus_tag="CCZ36_RS34265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="WP_128819342.1"
                     /transl_table=11
                     /translation="MNTTNRPRPRAILRIHFHPAERTDELYRQLLTVVDGISSRVEPLP
                     ADWSAYVDLTGALTYWGRDVEGLVAVLRLRLLALHGVQCSAGAGPTRSLAAMAADITPP
                     GAATVVRDDPYEIAAFLRTKPTAALPGIGPKTSRALARYGVTTVGDIADTQLPTLQRIL
                     GTGAARQAHDLAHGIDARPVVPGAAPKTMSTGHRFDRDELDPEQHHRTILRLVQELGAR
                     LRTSDEVAQALTLTVTYADRTQTARSRALPEATAHTPALATTACELLTGLGLQRARIRT
                     LALRAERLLPAEDAVHQLTFDDRDDKLRRIEVALDKAANRYRPGIAGVA"
     gene            complement(14886..18338)
                     /gene="dnaE"
                     /locus_tag="CCZ36_RS34270"
     CDS             complement(14886..18338)
                     /EC_number="2.7.7.7"
                     /GO_component="GO:0009360 - DNA polymerase III complex
                     [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /gene="dnaE"
                     /gene_functions="other (smcogs) SMCOG1194: DNA polymerase
                     III subunit alpha"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063843.1"
                     /locus_tag="CCZ36_RS34270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="WP_128819343.1"
                     /transl_table=11
                     /translation="MRESVPHLHVSSGFSARYGASHPQDLVARASERGIGALALTDRDM
                     VTGTVRFAKAATAAGVKPLFGVDLGIAPHVPPAEARRRTPVRGGAHVAEAPFRATLLAQ
                     DATGWARLCRLVSCAHAEAFAAGAPPAASWEMLGRYAGEGLVVLLGPASEPLRALVGGR
                     PDIAEQLLAPWQEAVGGGLRLEIVCWGLSGTGPGSVRLAAHTLALADRLGIPAVLTNAV
                     RYADRSQHRVADVLDAARLLRPVDRRRLDCGERWLKDGAAMTEIAERVAAAAGGGRARA
                     VRLLADTVAVAEACEVNPVRDLGLGVPHFPEPSVVGAEAGPGGAMRLLRQRCESGMAAR
                     GLDRDRRSMDQLDYELGVIGRLHYEPYFLAVAQVVADVRDMGIRVAARGSGAGSMVNHS
                     LFVATANPLEHNLLFERFLSERRSSLPDIDIDVESARRLEVYDRIIERFGRERVAVTGM
                     PETYRARHALRDTGLALGIAPATVDRIAKSFPHIRACDIRSALSELPELRELAAEAGRY
                     GPLWELAEGLDALPRGIAMHPCGVILSNTSLLDRLPVQPTPGGEYPMLQADKEDVEDLG
                     LLKLDVLGVRMQSAMAHAVTEIRRTTGKAIDLDNPDHVPLDDRFAFALIQNSDTVGMFQ
                     LESPGQQDLVGRLQPRGPQDVIADISLFRPRPVQGGMPALYIAARHGAAPAYPHPYLEP
                     VLRDTYGVTIWHEQIIDILAVMTGCDRALGEVARRALSNEERLPKVEAWFRQEAGARGY
                     SPTVLDQVWDVVSSFGAYGFCRAHAVAFAVPALQSAWLKAHHPAALYAGLLEHDPGMWP
                     ARVIVADARRHDVPVLPVDINASKAQYAVERTGSEWGVRISLATVHGISDDEVARITAG
                     QPYTSLQDFYARAHPKLPTVERLISVGALDQLKGEASRRDLLLQAAELHRQARTRPGAG
                     QLPLATTPHAANSSGLREMTARERLDAELGVLKIDVSRHLMEDHHRLLREIGATDAKHL
                     RAMHPGQRVLVAGVRASTQAPPIASGRRIIFVTLEDGSGLVDLAFFEDSHERCAHTVFH
                     HGLLLVRGTVEARGPRRTVVGEMAWDLDQLATARATHGPQAVLDLLGQDPSPTPAQPTP
                     APGRTIPDGTAGARLHPWSDLQPAGTRSADLTRFGHRSPGSPG"
     misc_feature    complement(18399..18414)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.74"
                     /tool="antismash"
     misc_feature    18400..18413
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            18606..19415
                     /locus_tag="CCZ36_RS34275"
     CDS             18606..19415
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143534.1"
                     /locus_tag="CCZ36_RS34275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TnsA-like heteromeric transposase endonuclease
                     subunit"
                     /protein_id="WP_237302803.1"
                     /transl_table=11
                     /translation="MTGTDQRAVWSHCCGFDELVVPYAVMCGEALDPRRDWTARWTVTW
                     QVDGSDIVCPVRDLATFPWTRAQPVRAFSWRPGQRHRPGLAFMGATGRGHGFESLAERR
                     ALTVLDFCGQVRDVLSQPFRLRFLDGARRTHIPDFLVATAGATLLIDVRPAHLVKESDV
                     TVFAATGRVAASAGWRYLVVTGWRNNVADTVEALARGRRRHTDPLGLEDQLLGAADRPR
                     RFGELVAATSWPVLARDHLQRLLWKRRLAFDLNGPLGDGTWIYPVGP"
     misc_feature    complement(20385..20394)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    20391..20406
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.73"
                     /tool="antismash"
ORIGIN
        1 gctcggccag gatcacggag tacttcgcca gggcctcgcg gtaggtgccg gtgaacggct
       61 gccggtcctc aagccgccag tagacatgct ggtcaagcga gccggtggtg atatcgaagg
      121 tcagcagggt ggcgggagcc agcagctgga tgccctggaa gggggtttcg accccgaccg
      181 gcgtctcgat cgcgaggacc tcgggccgca ggaccaaggg cgcgggcccg tagccggtca
      241 gagtggtgac ctcgctcgcg aacgcgagcc ggccgccgtc cagccgccag tagagcggct
      301 tctcgcccag ccggtcccgg gcgaggaaca gcttccctgg tcgcgggtca tagacggcga
      361 gggcgaacat gccatccagc ccgtccaggc aggacgggcc gatcttcgcc caggcccgca
      421 gcaggaagtg ggagtcactc tcgcggtcgc cgagcgggat gccccaggca gcggcttgct
      481 ggcggtagtt atagatctcg ccgttgaagg ccagcaggat cccgctctca cggtcgaggt
      541 aggggccggg catggcctgc gggtcgacga tcagcagcgt gttcatggcc accaccgccc
      601 acccgtccat cgcggcggcg tgcatggtgc cgtccgggcc tcggtgcgat tgcgaggcgc
      661 ccatcgcgcc gaccgtgtgc tcgtggcgga cggcgtcggc tccgaccagt cctgagattc
      721 cgcacatctg gttcaccccc gggtggtgcc tacggcggcc gccgccggaa ggagatctgt
      781 tccggttccg gcggcggcct ggactcacat cacagccgcc cggcaaaggc agggggaggg
      841 ctcgcagggg ggctcacaac tcgcaaggac ggttcgcggc cggtggagga ggaatatcgt
      901 tactgaccca acatgcggac cgcgtacgac tcttcgtccc cagttgagta cggatctctc
      961 gtgcccccaa gtgcagacat acgtactcaa ctgcgtgttc gagccgtgcg tggtccggtc
     1021 accggcagag ggagagtcgt ggcatcgacc acccgccgga cccgtccgcc caacgcggac
     1081 ctggcccggc tcatcgaagc cagcggcgcg agccacaagt ccctggctct gcgcgtcaac
     1141 cagctcgccc acgccgccgg gatagagacc gactattcac acacgtccgt ggcgaactgg
     1201 tgcaagcggg ggatgacgcc gaaatggccg gtccccaagc tgttgtcgca ggccatcagc
     1261 gagagactgg ggcggcccgt cagcctcggc gagatcggta tgggtgaggc ggagacaatc
     1321 gacgcatcgg tggggttgga tttcccgcga gaccccgccg acgccgtccg cgtcgccact
     1381 tcgttctgga gctccgtgaa ccgccgcgac ttcctggccg gatccggctt cgccgcgtcc
     1441 gccttcacca cccccgtcac ccgctggctc gtcactcccg ccgacgagac cgccgaccac
     1501 gccggcggga agcaggtcgg gcgggccgac ctcgccgaac tgcgtgacgc ggccgacgac
     1561 gcgaggcggt gggactccaa atacggcggc ggaaactgga aggccaactc cgtcaccgac
     1621 tgcctcgacc accgagcggg ccccttgctg cagggatcgt tctccgacga catcggccgc
     1681 gaactcttca gcgtgaccgc cgaactgtcc cggctcgccg gttggacggc gttcgacgtc
     1741 ggtgagcacg atgcagccca acggcacttc atccaggccc tccgcctcgc ccgcgcaggc
     1801 ggcgatgtac agctcggctg ctatgtcctg accaccatgg ccatgcagtc gctgatgcgc
     1861 ggattcgcgt ccgaggccgt cgatatggcc cagggcgcct tcaaccgagc caagggccag
     1921 gccgtcccga gggtgctggc gttcaccaag ctgatcgagg cccgcgctca cgcccgtgag
     1981 aacgacccca cggccgcctc acgggccctg aaagcctccg aggacctcct gggccaggcg
     2041 aaggacgaca gcggcgacga gcccgcatgg atcgacttct atcaccacgc ccgcctctcc
     2101 gcggacgccg ccgagatctt ccgcgacctg aagaacccca aggccgccct gacctggaac
     2161 caacaggcca ccgccatgcc gaccggggta ttcacgcgct ccgtcggcat gcggcttgcc
     2221 atcgtcggaa ccgcccacct ccaggccaga gacctggatc acggcctcga gctcggcaac
     2281 cgcagcgtcg acatcctcgc ccgcgtccaa tcgagccggg ccaaggacta cgtccgcgag
     2341 ttcaacaccg ctctcgcccc ctggcggcgc gagcccgccg tccgcgagtt cgtccagcgg
     2401 tcccgaaagg aactcggcgt cgccgcctga gtgcgaaccg cccgcggcct gcccgaacag
     2461 gtggtgaacc agccgaccgc gcgcgactac ccctgcgcta cggcttcgcc agctgcgagc
     2521 ttactgatcg tttcagaatg agttgagccg tgggtcttgc gctcgacgat cttggtcggc
     2581 agggtgtccg gcgtgcgtgc tgatcttgtt ccggatgacc tgtgggagcg ggtggccccg
     2641 ctgctgccgc ccgcccccga acggcgccat cgccacccgg ggcggctgcg tgttcccgat
     2701 cgagtagcgc tcgccggcgt catctacgta ctgcggaccg gtgtcgcgtg gcgtgacgtc
     2761 cctgcggagg cagtgggctg ttcaggtgtg acggcctggc gccgactgcg ggactggacc
     2821 gaggctggcg tctggccgcg cctgcacgcc gccctgttga ccgagcttcg tcgcgccagc
     2881 ctgctggacc tggacgactg ctccgtggac ggatcgcacg tccgggcgcc gaaaggggga
     2941 ccacgtcgga ccctcgcccg tcgaacgggc ccgctctggc tcgaagcacc acctgatcgt
     3001 cgaccgtcac ggaaccccgc tcgccgtcac gctcaccggt ggcaaccggc acgacgtcac
     3061 ccagctcctg cccctgctcg acgccgttcc gtcgattcgg ggtctgcggg ggcgtccccg
     3121 ccgcaagccc cggcgcctgt atgccgaccg gggctacgac ttcgacaagt accgccgcct
     3181 gctgtggaaa cgcggcatca agccgatgat cgcccgacgc ggcttcgctc acggctccgg
     3241 actgggcaag gtgcgctggg tcgtcgagcg tgccttcgcc tggctgcacc agttcaaacg
     3301 gctccgcacc cggtacgaac gacgcgccga tctccaccag ggccttctcg aacttgcctg
     3361 cagcctcata tgcctgcgcc gcctgcgcac ctcatcctga agcgatcagc tagcgacact
     3421 gaaccacccc ggtcgcacct cggtcagaag cggctgaagg gaccgcacgg cggtccgcag
     3481 gtcctgatcc gtgacgtcaa gaggctcagg caggctcagc ccgtaccagc gcagccgcca
     3541 gaggtcgaag atctcgctcc cgtcgggtgc gaagtcgaca tcgacctcga tgccgtcgtc
     3601 actgacaaag cggcacccgg ccccatgaac cgagtaggag taggtaccga cccgcccact
     3661 ccggttgatg atccggtgcg aacggaccag gccgaggaca tctgcgagtc gctcaagcga
     3721 agggatcgcc gccctcatgg ccgcgtcaac tgcgttcaga gcgtcgacgt aaccaagaac
     3781 gagccctcgt gcatccccaa cccgttccat acggcgtcat ccccctgagc ccgtggttga
     3841 aggggattgt tccatgggcc gccagcatct ccgcagggcg gcattctgaa acgatcagtt
     3901 aaagagcgtt ttgtgccggc aggagcgcat catcacaatt cgggtgatgg aacggctagg
     3961 gtcggctgag gcttcagacg tctgttgtgg caggtggggc gggtgacgtc tttcgagggt
     4021 ccgtttcagt cccttcgctc ctgtctgatc ccaacacgcc cccggtcgcg cctgtttgcg
     4081 ccctgtaatg ggagagccgt catcgctact acagaaacat gcctctcaga tcgcgaccgt
     4141 atccgagcga cttgtccgat gcccgttgga aactgctgga accaactctg acagcctggc
     4201 ggaccgaacg aagagggaag ggccgggaca tcggccggcc gcccgagcac gatctgcgcc
     4261 ggatcatgga cgccatcctc tacgtcgacc ggaccgggat cccatggagg tatctgccgc
     4321 acgacttcgc tccgtgggaa accgtctacg gatacttcgc cgcctggcag aaggacgggg
     4381 tctttgacca gctcaacggt cttctgcggg cctggtccgt aaggctgagg gccgcgatgt
     4441 cgagcccagc gcctgcgttc tcgacgccca gagcgtcaag acctcggcca acgtgccggc
     4501 ggtcggccag ggcaacgacg cgggcaagaa gatcgcgggc cgcaaacgtc acctaggcgt
     4561 cgacaaactc ggcctcctcc tagccgtgct ggtcaccgcc gccagcgtct ccgacaacgc
     4621 cggtggcatc catctactct cggacattgc cgcaggccac ccgcgcgtca caaaggcacc
     4681 acggtgcccg cttgggcatc aatgtcgaag tcacgcgtcg cgaccccgcc cagaagggct
     4741 tcaaggtgat tccgcggcgc tgggtcgtcg agcggacctt cggctggctc atgcatcacc
     4801 gtcgcctcgc ccgcgactac gaaacccacc cccaccgctc tgaagccatg atcaaggtgg
     4861 ccatgatcga cctcatgagc cgacgactca cccacgaatc cacctcgaac tggcgcgact
     4921 cctgagtcag gaggaagcgc cctgagcggg gcagtgccag tcggccgagt cgatcgcgtc
     4981 ctcctccgtg tcactgaggt gaaagcagtt tccgttgacc cacaccgtga ccgattcggg
     5041 ccgatggtcg acctggaatg gttcgtcccc cccgcagagt tccggaccat gagccatccg
     5101 ctgcaggcga gtgggtgaca atgacccacg tctgctctgg gagtatctgg tacgtgtccg
     5161 cccagggctc cacggtcaac tccagcgcgg actcacctcc attgctaatc agcagccgca
     5221 ctgttccgac actgtccatt ccccgcaccc ctccttgcct ctacgggcga tcccgcacgc
     5281 agctgcagag tacgggccca cacgacccga tcgtcacgca cgcacgaccg cctgaagtcg
     5341 ccctgccacc cgagatatca aacagccctg ccgggacaaa acgctctttg agcctgcgcg
     5401 aatagccgca gccgccaagc gcgcgatact ccagtgcgct tggcggctcc attggccgta
     5461 tgaccggtgg tcagcggttg tcgtcgagtt cttggtgcat ctggggctga tcgtcctggt
     5521 cgtgggtgag tgcgtactgc tcgatctcgt tgaacgcctt cgaggcgact cccaggaggt
     5581 ccttgtaggg gttgacgccg acggtccgct gggtggctcc gccgaagagg ccgcctgccg
     5641 ttccgctgac gaggccgtgg cctgcggcga gcggcttgcc cgcgaggtcg agggggctct
     5701 tgggcaaacc ggccatgtcg gcgtacttgt cggtgagcgc aacgcgggtc agcgcgatgt
     5761 aggcgtcact ggcgccgggc ttcaggaggt cgcggtagaa cttgatggcc tgggcggtca
     5821 tgaagacgcc gtcgtcggtc ttctgccatt ccttgtcccg ctcctggttc cacagccgtt
     5881 cggcttcgtt ggcgtccttg ggcagctgcc acttctccgg cgttccgagg tagtggttga
     5941 cgtagtgcca ggcgcacatg aagccgcggg cgtcgtcggc ggagacgtcg atgccgaggt
     6001 tcctcatgcc ctggaggatt tgggtgctga agatacaggc ggcgccggtg gtgtacttct
     6061 gggagaccgg ctcgccccac ttgtcgtagt cccactggcc gctctgcttg tgcagttgcc
     6121 tgaccgaggc gtgcacgagg cgcaccttcg tcacggtggc ggccagggtc ccgtcgcgca
     6181 tggcgttctt gttacccatg tcgatgaaca gacgggagga ctgcgacagc cttcggcccg
     6241 gtccctcgac acctcccagc cggccggtgg agcgcagggt gaatgccccg gtgggtgcga
     6301 ggtaggtgcc gatgaggccg acggtgccct gcagcatcga ggcggttccg tggtggtggc
     6361 cgaagaagcc ctcggcggcc ttgacgtctg cctcgctcca gtccggcggt ggggtggatg
     6421 cctcccgaag gaactgggcc agtcgatcgg gaagccgcga caaatccgtg tcgggcttga
     6481 gcgttccgat cgtccggaag agggcgttga tcccgtcgat ttccctgttc tcgaggaggt
     6541 cggccaccag cgcatcagcc gcaggatctc cgaccttgct cgcagcctcc aactcagctg
     6601 taaccgttgc cgatgtcaac gccatagcaa tactcctcgg tattcatcca attgacatgc
     6661 aatgggtgac ctgcgcacag acgcactccc gcccaggggg cgccccttgg tgctgcgcga
     6721 gaagaccctg gattgccgct ctcgcagagg gaggaccatc gtgcgggctg ctcgatgggc
     6781 atgaatgaga aggactcgtg cggcaagatc acttcacttc gatcttgccg caatcgtcgc
     6841 ctcgagttgg tcacccaata ggagtaaggg ggcgtgcgcc ccgcgtgaat cagggagtgc
     6901 gcggagattg ccgtttcggt cggtggtgtg ttgcgctgcg cgcgttatca ggccgcagcc
     6961 gggtgactgc cgggttggcg aagccccttc agcgggtggc gtccatacgt cttcttccaa
     7021 gccgcggtgg catcctgctt gtcaggttgg gccagtagca gcacgccgtc cgccgtggag
     7081 agctccgcgc cggacaggca ccggttcacc ccggatagct ggctctcctc gatcgggtga
     7141 tcatcttccg aaaaagcggt ttggcacaaa tctggcccgt caagatcgcc cgtatgacta
     7201 tccgtcgctg ggccgctgcc gcggccgcta tcttttccgt cgcagtcctg acagggtccg
     7261 ctcaagccgc acccaccgcc gcccccgtcc cctcggggcc tgttgtcatc accaacgacg
     7321 cccacaccaa ctacctggtc cctgacgaca cggtcggcaa cgccggcacc ttcctgcagg
     7381 tctactaccg ccacgaccat cccttcccgc gcactttcca gttcgagcag gtgaacgggc
     7441 gtcccggaat cttccactgg aagagcgccc gaactgggaa ctgcgccgac gccaaggccg
     7501 gagagccggg ggctcggtgt acctggctgc gtgcacgacg aacaagtccc agtggtgggt
     7561 cctcaggtcc accgacgaga gccctgcacg gtgggttctg tcgcccttcc tgaacgagga
     7621 cgttgctgtc accggcttgt tcggggacga caactacgca ccgctgcgtg aactgcccaa
     7681 ccccaactct ccaaccactt cgcagatgtg gcacttcacc cggcagtgat tgcgttgacc
     7741 ttcggtgctg cgttccgcgt agggctccgc cccgccctac ggcagggccc tgcgcgggaa
     7801 gctggtggcg gagcggcacg gtgatcagct gccggatatg agccgccggc ggcacgtggg
     7861 aatgggtcct gacgtcgaag tctcgtgacg gtccaccgac tgagtcggtg gaccgacttc
     7921 gtgctgtggg ccgaggctgc acagaccggg ggcccgattg ccgtcccgag gtggcaagcc
     7981 ctgcaccagc cgaggtggtc gcccttcgcc gcgtagctga gccgcagaag cgaggaggcc
     8041 gctgttgtgg caggcccacc gcccggcccg tgagggcggg cagggccggc tttcggtcgg
     8101 aacgggggtg ctgccggggc cagagtcgtt ggggctcacc caccggggcg tggacggtct
     8161 ctgcgtcggc ggcggtgatg tcgagcaggc cgagcccggg gccgctgagc cgccgaggct
     8221 gagaggggag gctcgtccgt gacgcaaagc agattaatga tctactcgtc gtcactgggt
     8281 ggagagggcc ccgctgtcgc tggaggcccc ggtagaggat gtggtggtgc cagtggggcg
     8341 gggctcgcga gtcgcggtgc tgggtggggc gtggccgggt tgacggcggc gatggagctg
     8401 gcggagcgcg gcttcgaggt gacggtggtg gagccggccg gttggggtgg caaggcgcgc
     8461 agtgcgtggg tggcggggac cggccgcggc gggcggttgg acctgcccag tgagcacggg
     8521 tttaggttct tccccgggtt ctaccggagt ctgccggaca ctttgcgccg tatcccggtc
     8581 gacggcagcg cggaaggggt ggcggggaat ctgcgggagg cgacgcagat gctttccgcg
     8641 cgctcgggcc gggtgggtga gcgggtcacc gatgtgtccg tggctgcggg ggctcggact
     8701 ccgatggagt tcctgcgtgc tgtcgggctg gaggcgggtg gcagggggct gacgagcgag
     8761 gagctgctgt acttcgcgaa ccggatgctc gtctacatga cgagcagtga cgagcggcgg
     8821 ctgggccagt gggagtcgac ctcgtggtgg gacttcgccg cggccgacgg cgcctccgag
     8881 gagtacatca aggcgtgtgt ggtgggcgcg acccgcaccg tggtcgcggc acgggccgag
     8941 gtctgcagtg cgcacacggt cggcgggttc ctggaggctt tcagctacgg gttcctgggc
     9001 cggggcgagg aactgcagcc ggcggaccgg gtcctcaacg gccccaccag cacagcctgg
     9061 atcgacccat ggatccgtca tctggcatcc ctgggggtac ggctgaaact cggatggggg
     9121 gtcgagcgtc tggccctgag cggtcgccgt gtcaccaagg cccaactgcg aggcccgcac
     9181 ggccagcggc gggagctgga agctgactgg tatgtctgcg cgctgccggt ccatcgcatc
     9241 ggcgcactgc tggaccgcgg gctcgcggag gccgacgccg agctcaagag cgtgacgggc
     9301 ctgcacacgg actggatggt cggcatgcag ttctacctga cccagccggt gccggtcacc
     9361 cacggccatg tcctgttcct ggactctccc tgggcgctca cctcgatcag ccaggcccag
     9421 ttctgggacg gcgacttccc tgccacctac ggcgacggaa ccgtggccga ctgtctgtcg
     9481 gtggacatct cctcctggga caccccgggc atcctgtacg gcaaaccggc ccgtgagtgc
     9541 agccgggcgc agatcgcggc cgaggtctgg gcgcagctgt gcgacgggct caacggagct
     9601 ggtcgaaccc gcctgcacga ggggttgctg cacacgtggg agctggatcc ggcggtgcgg
     9661 aaccttgacg ggccggggcc ggccgtaaac gacgagccgc tgctgatcaa caccaccggt
     9721 tcctgggcgg cgcgcccgcg ggcggtgacg gcggcggcga acctgttcat ggccggggac
     9781 tacgtgcgct cccccgtgaa tctggcgacg atggagggcg cgaaccaggc cgcccgcatc
     9841 gccgtgaatg ccctgctgga ggcggccggt ggcgccgggg ttcccgcggc cgtgcacgcc
     9901 ctgcaccagc ccggggagtt gcgcaggctc aaggaggtgg acgccgagct gttcggtcag
     9961 gggcgggctc acatcatgga cgggctgccg ccgtggaagg tcagtgcacg cgtctgatca
    10021 cgaccgtgca gagcgcttcg aggtcttcga gagctgaggg tagtgctgtg aggcggtgga
    10081 gccggtcgcg tgcggctgtt gcgtgctggg cggcgcggtc gctggtccag gcccggccac
    10141 ccgcctcctc gaccaggcgg gcgaggtcgg ccgtatcgct gccgggctgg gcgtagaggc
    10201 gggcgagttc gtcgccggcc ggggtcccgg agcccagcgc ggcgaccacg ggcaccgaca
    10261 tcttgcggtt cttcagatcg ttgaagacgg gctttccggt cactgccggg tcgccccaga
    10321 tgccaagcag gtcgtccacg agctggaagg ccatgccgag gtcgtgcccg aactctgccc
    10381 actgggcgca gacggccggg tcggcgcctc cgtagagggc acccaggcgg caggcgcagg
    10441 cgaacagtga ggccgtcttg cccgagacca tctccaggca ctccgccaag gtcacctgcg
    10501 ttcggccttc gaagaccagg tccaggctct cgccgacggc cagttggatg agcacgtcca
    10561 ccagggcggc cgacgcctca cgagccaccg gcccgtccgg cccgtcggct tccgacagga
    10621 cgtcgaacgc ggtcagcatc atggcgtctg cggaccgggc tgcggacgac gggccgaaga
    10681 cctgccaggc ggccggccgg tggcgccgca tcgtgtcacc gtccagaaca tcgtcgtaga
    10741 gaagcgacag gttgtgcacc atctccacgg ctgcggccgc tggcaccgcc ggccggtccg
    10801 cacctcccac cgcacgcgca cacgccaggg tcagggccgc gcgcacgtac ttaccgccct
    10861 gccgtgcgcc ctcccccgac cagccgaact gataggcagc cacctcagca gcgggtccct
    10921 gaagtgaccc cacccaccgt cgcagctgcc ctttgcaagc atcgcccgcg ctgcgcaata
    10981 cctcatcgac cgcgcccacc gtcaagcccc ctatcgtcag ctccacacga aaccatgcgc
    11041 ctctctgccc cggctgtcgg cgggcaggat tcctccaggg gtccatcatg gcgggcccgg
    11101 ccggtacata acgtcgccac ctcaccgggg cccgagaggc cgcgaaggac gcccacgaca
    11161 ccttcgtgaa caccgccgcc cactacctcc gccccgccag caccctcccc accaccggac
    11221 aggagagccc ccgatgatcc gtcgcctgcg ccgctgcgga catgcccccg gagccatctc
    11281 ccccgaggac caggccgtcg tcgacgagtt ccgcgcgatg ctcaccgccc tgcgcaaccc
    11341 cgagccctgg acgccgggca ccggcagcgc ccgggacatc gccgtacgcg tcggcccgtt
    11401 cgtggaacgc gcgcacaccc gccccggcga cgaccacggc cccgacctca tcgccgtcac
    11461 cctggtccac cctgacaccc cgcacgcggg cgcctacctc cacggccgcc agctcggcta
    11521 caccgaacac gactggctac gctgcccgac tacgtcgatc gtcggctact ggcagcccgg
    11581 atacacgcag ctcacccacg ccgccaacgg cctgcacctc cccgacgaca tcggcatggc
    11641 ccccgccaac tacgcgctct acatcgaggc ccgcaaacgc gacgacagcc acgacggcca
    11701 caccctgctc cggctcggcc cgtacaccca gccccggcac gcccagcagg acggcgaccg
    11761 gctcaccgcc gcactgaacg gacgggagac caccctcgtg cccggctacc gcatcaccat
    11821 gaggttcgga ccgctaaacg tcagcgacca ccagctgttc accgccccgc acgaggccga
    11881 cgccgtgtcg ctcctggacg ccgaggcaga caagggctcc ccgcgcttgc ctgcctgcgt
    11941 gggcagcggg ctactgctca gcgcgcagcc accctgggat cgttcgtcgg cttacgcccg
    12001 acagggcctc aagccgcgaa ggccccacac cgccagcagc gctcttccga agcaggcgcc
    12061 gcacctcgct atccgcgaag gcgagtcggg acagagccac ctgccgctgt actccagcca
    12121 aagccagttc gtccgtcgcg ctcaacgttg gagccggatg ctcctcctcc caccgaaaga
    12181 cgtcgtcggc caattgctcc cacttgtacg gctcgggcgg agctgacctc cacttcgcgt
    12241 tccgcagaag ctcctccgga ggtaccgcgg ccgcacgaag ggtctgcggg agagtgaggt
    12301 cccgccatgc caaagggagg tgccccggac gaggcccacc ctggatgcca agatcagcca
    12361 ggcagtgggc acaagatcgg tggagctgcg cctcgtccgt cgagtcctgc aaacaacggg
    12421 atgcaggtag tcggcacagc accgggatcc cgtacgacaa ggagtaggcc gcgtgcgggg
    12481 cccgatgccc acacgcgtcg tcatcaagat gaggcgtaat tcgaagtagc ggctcaccca
    12541 ggaacgaagc cttgcgggcg gtgccgtcga gcgtttcgaa cacctcgtac tcgcatcgcc
    12601 gccgtaacgc ggtcctcaaa tgatcaacag gggccgcctg cggccactcc tcaaccaacg
    12661 ccgtccacat agggtgggca cctcttctcg cctgtggcgg gaagggcccc cacctcctgg
    12721 aggatctagc agggggattc ccgggcgagc aactcgatgt cacccacacg ggttaggccc
    12781 gtgcgcgtcc gcgatgggcc aagctgcaca ccgcgaacag cgacagcaac ctggaagcca
    12841 aactcgcggc ggtaggcccc aaagtcgagg gccccgcggc gggtgcgaag tgcagcgtga
    12901 ccttgtgcac ctgagctcgt tgtgccgttc ggaccgcctg cggcgacggt ctcggctgtg
    12961 ctctctcggc ccgtgaacgg tgagcaatac aagcccgaag gtgctccgca tcctcgctgg
    13021 actttgagat ccgatttgct caacgtgtcg gatcacgggg ccggtgcggc tggagcgagc
    13081 agtgaccaag ggccacgcac ggaagagaga agtacgccgc cgtatgaaag aagaaggcca
    13141 gagctaccaa gccacgctgc gtgagcagct ccaggatggc tcggacgcga gccccgacct
    13201 gccgaacgcg gacagccgcg aggactacat cgacgctgtc tgggacgctg atctacctca
    13261 gatggtcaaa gtgctgcttt acgagctcgc ctccaggctg gacctgacag ttcccgactg
    13321 gaggaccaac agccaccacg tccgtttcga ggaagaggag ctggctcgcg cggtcggcct
    13381 cgacgtcgaa gctgcgaacc tgtgccgcga cctcgccctt gaggcgaact ggctggtgga
    13441 ggtcgacgag gaaatggtgg agctccggga gccacatcag gactgggacc tctttgcagg
    13501 cgcattgcgg gaccacaagg aaccaatcgt cgatcgggtt gtctaccgga gtcgactagc
    13561 ggccttcgac tcggagacca agcgtctgag gacagatccg ataatgtcca tccgtcgtct
    13621 ccgcgcgggc atggcggccg tcattgggca caccttcgtg cccaagtgcg tcggaggacc
    13681 attcactcag gacacggtag ggctgggctc aggtcagtgc tccgatcagc cgtaacgctt
    13741 tggtgagtga gacgggcgga gctgctggat agctccgccc gcagccaaga cctgctgaga
    13801 aagctgaaca gccgctgccc tcacaacttc tgtgcgcctt gaacctcaca cagggctttg
    13861 cacgctggcg gtcgtctatc cggatcgagg gaaggcctat gccacgccag cgatgcccgg
    13921 tcggtagcgg ttcgcggcct tgtcgagggc cacctcgatg cggcggagct tgtcgtcgcg
    13981 gtcgtcgaag gtgagctgat ggaccgcgtc ctcggcaggg agcaagcgtt ccgcgcggag
    14041 ggcgagggtg cggatgcggg cgcgctggag gccgaggccg gtgaggagtt cacaggcggt
    14101 ggtggccagg gcgggggtgt gggcggtcgc ctcggggagg gcgcggctgc gagcggtctg
    14161 ggtccggtcg gcgtaggtga cggtgagcgt gagtgcctgg gcgacctcgt cgcttgtgcg
    14221 cagccgggcg ccgagttcct ggacgaggcg gaggatcgtg cggtggtgct gttcggggtc
    14281 gagttcgtcg cggtcgaagc ggtggccggt gctcatggtc ttgggtgcgg cgcccggcac
    14341 gacgggtcgc gcatcgatgc cgtgcgcgag gtcgtgggct tggcgtgcgg ctcctgtgcc
    14401 gaggatgcgc tgcagggtgg ggagctgggt gtcggcgatg tcgccgacgg tggtgacgcc
    14461 atagcgggcc agagctcggg aggtcttggg accgatgcct ggcagggcgg cggtcggctt
    14521 ggtgcgaaga aaggcggcga tttcgtacgg gtcgtcgcgg accacggtgg cggcgccggg
    14581 cggggtgatg tcggcggcca tggccgcgag ggagcgggtg gggccggcgc cggccgagca
    14641 ctggacgccg tgtagtgcga gcaggcgcag gcggagcacg gcgacaagcc cttcgacgtc
    14701 gcggccccag tacgtgaggg caccggtgag gtcgacgtac gcggaccagt cagcgggcaa
    14761 gggctcgaca cgggagctga tcccgtcgac gaccgtgagc agctgcctgt agagctcgtc
    14821 ggtccgttcg gcggggtgga agtggatccg cagaatcgcg cgcggccgcg gccggttggt
    14881 ggtgttcatc ccgggctccc ggggcttcgg tggccgaagc gggtgaggtc ggccgaccgg
    14941 gtcccggcgg gctggaggtc gctccacggg tgcaggcggg cccccgcggt gccgtcggga
    15001 atcgtccgcc cgggcgcggg cgtgggctgg gcgggtgtgg gggagggatc ctggccgagg
    15061 aggtcgagga cggcctgggg cccgtgggtc gcgcgggcgg tcgcgagctg gtccaggtcc
    15121 caggccatct cgccgacgac ggtgcgccgg gggccgcggg cttcgacggt gccgcgaacg
    15181 aggagcagcc cgtggtggaa gacggtgtgc gcgcagcgtt cgtgggagtc ctcgaagaac
    15241 gccagatcga ccaatccgct gccgtcttcg agggtgacga agatgatcct ccggcctgag
    15301 gcgatgggcg gggcctgggt ggaggcgcgg acgccggcga ccaggacgcg ctgcccgggg
    15361 tgcatcgccc gtaggtgctt cgcgtcggtg gcgccgatct cgcgcaggag gcggtggtgg
    15421 tcttccatga ggtgccggga gacgtcgatc ttgaggacgc cgagctcggc gtcgaggcgt
    15481 tcgcgggcgg tcatctcccg taggccggac gaattggcgg cgtgtggggt ggtggcgagc
    15541 ggcagctgcc cggcccccgg tcgggttcgg gcctggcggt ggagctcggc tgcctggagc
    15601 agtagatccc ggcgggatgc ctcgcccttg agctggtcga gggcgccgac gctgatgagg
    15661 cgctcgaccg tggggagctt ggggtgggcg cgggcgtaga agtcctgcag agaggtgtag
    15721 ggctggcctg cggtgatccg ggcgacctcg tcgtcggaga tgccgtgcac cgtggccagg
    15781 gagatccgca caccccactc cgatccggtc cgctccaccg cgtactgggc tttggaggcg
    15841 ttgatgtcga cgggcaggac ggggacgtcg tggcgacgag cgtccgcgac gatgactcga
    15901 gccggccaca tgcccgggtc gtgttccagc agccccgcat agagagcggc cgggtgatgc
    15961 gccttgagcc atgcggactg cagcgcgggc acggcgaacg cgacggcgtg ggcccggcag
    16021 aacccgtacg cgccgaacga ggagacgacg tcccagactt ggtccagcac cgtcgggctg
    16081 tagccgcggg cgcccgcctc ctgccggaac cacgcctcga ccttcggcag ccgctcctcg
    16141 ttactgaggg cgcggcgggc tacttcgccc agggcgcggt cgcagccggt catgaccgcg
    16201 aggatgtcga tgatctgctc gtgccagatc gtcaccccgt acgtgtccct gagaaccggt
    16261 tccaggtagg ggtgtgggta tgcgggtgcg gcgccgtggc gggcggcgat gtagagggcg
    16321 ggcatcccgc cctggaccgg acgcggacgg aacagcgaga tgtccgcgat gacgtcctgc
    16381 gggccgcggg gctggagccg gccgaccagg tcctgctggc cgggtgattc cagctggaac
    16441 atccccacgg tgtcggagtt ctggatgagc gcgaaggcga accggtcgtc gagcggcacg
    16501 tggtcggggt tgtcgaggtc gatggccttg ccggtcgtac ggcggatctc ggtgacggcg
    16561 tgcgccatcg ccgactgcat ccgcaccccc agcacgtcga gcttgagcag cccgaggtcc
    16621 tcgacgtcct ccttgtcggc ctggagcatc gggtactcgc ccccgggggt gggctggaca
    16681 ggcagccggt ccaggaggct cgtgttggag aggatcactc cgcacgggtg catcgcgatc
    16741 ccgcgcggca gcgcgtccag gccctcggcg agctcccaca acggcccgta ccgcccggcc
    16801 tcggccgcga gctcccgcag ctccggcagc tcggagaggg cggagcggat gtcgcacgcc
    16861 cggatgtgcg ggaacgactt cgcgatccgg tccacggtgg ccggggctat cccgagcgcg
    16921 aggccggtgt cccgaagcgc gtgccgggcc cggtaggtct cgggcatccc ggtgaccgcg
    16981 acccgctccc gcccgaaccg ctcgatgatc cggtcgtaga cctccagccg gcgcgcggac
    17041 tccacgtcga tgtcgatgtc cggcaacgag gagcggcgct cggacaggaa ccgctcgaag
    17101 agcaggttgt gctccagcgg gttcgcggtg gcgacgaaga ggctgtggtt gaccatggag
    17161 ccggctccgg aaccgcgggc ggcgacccgg atgcccatgt cccgcacatc tgcgacgacc
    17221 tgggcaacgg cgaggaagta cggctcgtag tggagccggc cgatcacgcc gagctcgtaa
    17281 tcgagctggt ccatcgaacg gcggtcccgg tcgagaccgc gggcggccat gccgctctcg
    17341 caccgctgcc gcagcagccg catcgcccca cccggccctg cctctgcgcc gaccacagac
    17401 ggctcgggga agtgcggcac cccgagcccc aggtccctca ccgggttgac ctcgcacgcc
    17461 tccgcgacgg ccacggtgtc ggcgagcagc cgcacggccc gcgcccggcc gcccccggcg
    17521 gcggccgcga cccgttccgc gatctcggtc atcgccgccc cgtccttgag ccagcgttcc
    17581 ccgcagtcca gccgccgccg gtcgacgggc cgcagcagcc gggccgcgtc caggacgtcc
    17641 gcgacccggt gctgggaccg gtcggcgtac cgtacggcgt tggtcagcac ggccggaata
    17701 ccaaggcggt cggcgagtgc cagggtgtgc gcggccaggc ggaccgaccc cgggccggtg
    17761 ccggacagtc cccagcacac gatctccaac cgcagcccgc caccgacggc ctcctgccac
    17821 ggtgccagga gctgctcggc gatgtccggg cggccaccga cgagcgcccg cagcggctcc
    17881 gacgccggac cgagcagcac aaccagtccc tcacccgcgt accggccgag catctcccac
    17941 gaagctgccg gcggcgcgcc cgcggcgaag gcctcggcgt gcgcgcagga cacgagccgg
    18001 cacagccgcg cccaccccgt cgcgtcctgg gcgaggagcg tggcccggaa cggtgcctcg
    18061 gctacgtgcg ctccgccgcg caccggggtg cggcggcggg cctcggctgg gggcacatga
    18121 ggggcgatgc cgaggtcgac gccgaacagc ggtttcactc cggcggccgt ggcggccttc
    18181 gcgaagcgca ccgtgccggt gaccatgtcg cggtcggtca gcgccagcgc cccgatcccg
    18241 cgctcggacg cccgcgcgac gaggtcctgg gggtgcgagg cgccgtagcg ggccgaaaac
    18301 ccactgctga catgcaggtg agggacgctt tcccgcacga caccctccgc ccataacccc
    18361 caaagcgtta ctaatcgaac ccttcttcat cgattgtatc gaacattaat tcgaacatgc
    18421 gagtttgaag cgcgggattt cagccagcca ggtcgttgag actgagcacg atagatggcc
    18481 cttgagcacg ctagttggcc tctgagcgtg ataggtggcc cgcagggtag tgggtggatc
    18541 atcctgatca cggctgtttc tgcgttctgc ggatttcggc atgttccgcg cggtgtgctg
    18601 gtggcatgac gggtactgac cagagggccg tgtggtcgca ctgctgtggg ttcgatgagt
    18661 tggtcgtgcc gtacgcggtg atgtgcgggg aggccctcga tccacgccgc gattggaccg
    18721 ctcgctggac ggtgacgtgg caggtcgacg gaagcgacat cgtctgtccc gtgcgcgatc
    18781 tggccacctt cccctggact cgggcccagc ctgttcgcgc gttctcctgg cgcccggggc
    18841 agcggcacag gcccgggctg gcgtttatgg gggcgacggg ccgcgggcac ggcttcgaga
    18901 gcctggccga gcgacgcgcg ctgaccgttt tggacttctg cggccaggtc cgcgatgtgc
    18961 tctcgcagcc gttccgcctg cggttcctcg acggggcccg ccgcacacac atcccggact
    19021 tcctggtggc cacggcgggg gcgacgctgt tgattgatgt ccgtccggca caccttgtga
    19081 aggagtcgga tgtgaccgtg ttcgcggcga ccggccgggt ggcggcttcc gctggctggc
    19141 ggtacctggt ggtgactggc tggcgaaaca acgtcgcgga caccgtggag gccctggcac
    19201 gcgggcgtcg ccggcacacc gacccgctgg gcctggaaga tcagctcctc ggggcagcgg
    19261 acaggccccg tcgattcggc gagctcgtcg ccgcgacgtc gtggccggta ctggcgcggg
    19321 atcacctgca acggctgctg tggaagcggc gcttggcctt cgacctgaac gggccgctcg
    19381 gggatggcac ctggatctac cctgtggggc catgatggcc gacgcgggtg accgcacgcc
    19441 gttggtcgag gagctcaccg agcaggatct ggctcgcctt cgcatccggc tagagcacct
    19501 catggaggtc gagaccggat tccgcagtgg cagccgtcac tgggcccgac cagatgagcc
    19561 ccggccagcc ttcgaccctg cgaccaccaa cctcggagag cgccgcttgg ccaaggttgc
    19621 cgagctcggc gcgctgccgg agaccgaggc cgcccgactc gggctggagt cagtcagcga
    19681 acgcaccctg aagcggatgg ccgcccgcta ccgcgagtcc ggcctcattg ggctggtcga
    19741 cggccggtgg acgcggcagg ccggcggcca cccatcggtg acggccgatg tggaggaggc
    19801 gatccgggcg gtgcatgagc agtgcctgcg caggtcgcgg atcagcatgg cctcgcggga
    19861 gcggttgatc caccagtacg tgcgggaggt tttcccggac cggcaggtgc gggtgccgca
    19921 ccgcacgacg ctggcgcggg tgtggcggga gtggttcggg cccggcgggt cccgccagcg
    19981 gtacgtacgc tcggccgccg cggtccccgc accggccggg gtaccggtga tcgcgtcgcg
    20041 gccggggcag gtggtggtgc tggactcgac gcctttgccg gtgaaggtcc tcgacgacgt
    20101 cttcggcacc ccgatcaccg tgcacctgac gatcgcgctg gacgcctaca cgcactcgat
    20161 cgtcgcgttc cggctgacgc cggtggcgga gtcgtcgatc gaggtggcga tgctgctgcg
    20221 ggatgtgctc tcgccgctgc ccatgcgtcc gggctggggc gcgaccatgg cctggccgta
    20281 tccgggggtc ccagccgcgc tggtggccga cttggcgggc gggccggtgg ccgggctgcc
    20341 gttcttcacc ccggaggcga tcaccgtcga ccacgggtcc gcgttcaaga atcaccacct
    20401 ggtccaagta gcccgcacgc tcggcgtgga cgtgctgccg gcccgggcga tgcggccgac
    20461 agacaaaacc gcctgcgagc gggctttcgc cgcgatccag tccctgctcc tggaactcct
    20521 acccggttgg cgcggcatcg acgtcgccga ccgcggcgcc gacccggaag cggacgcggc
    20581 gtggacggtg gcagagatgg agcacctgct cgcctcgtgg atcgtctccg tgtggcaaaa
    20641 ccggcgcctg gaccagcacg ctccggcctg ggacccctcg ggccggcaca gcccgaacac
    20701 cctcttcgcc gccgcagcag cccgcgacgg catcgccttg gagatcccgg cgcccgagct
    20761 gtactacgag ctgctgccgg tgcacttcgt gaagatcgac gcccggcgtg gagtgaaggt
    20821 tggcggcctc tggtacgggg cccacagccc ggccctcgac ccgtgccgcg gtgtcccggc
    20881 accgcgcggt gggcggcatg ccg
//
