LOCUS       NZ_CP021707            27822 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. S063 chromosome, complete genome.
ACCESSION   NZ_CP021707
VERSION     NZ_CP021707.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S063
  ORGANISM  Streptomyces sp. S063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Complete genome sequence of Streptomyces sp. S063, a producer of
            anti-complement compounds and various secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAY-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:19:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,905
            CDSs (total)                      :: 6,817
            Genes (coding)                    :: 6,244
            CDSs (with protein)               :: 6,244
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 574
            CDSs (without protein)            :: 573
            Pseudo Genes (ambiguous residues) :: 0 of 574
            Pseudo Genes (frameshifted)       :: 432 of 574
            Pseudo Genes (incomplete)         :: 192 of 574
            Pseudo Genes (internal stop)      :: 13 of 574
            Pseudo Genes (multiple problems)  :: 61 of 574
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7185290
            Orig. end                         :: 7213112
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021707.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Xinqing Zhao, Life Science
            and Biotechnology, Shanghai Jiaotong University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27822
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="melanin"
                     /product="terpene-precursor"
                     /region_number="26"
                     /rules="melC"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..27822
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="neighbouring"
                     /product="melanin"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10477
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10477
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5477](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5477
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     misc_feature    1379..1399
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            complement(2096..3355)
                     /locus_tag="CCZ36_RS32610"
     CDS             complement(2096..3355)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964394.1"
                     /locus_tag="CCZ36_RS32610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyl hydrolase"
                     /protein_id="WP_069736034.1"
                     /transl_table=11
                     /translation="MPAKRRLFVSCIAALALSLLAGGGIAGQSPPGTDSVDGAAPGGPR
                     AGSATAHGAYLDYGPEGVSRMADFSRWLGGAELRVGHTYLPGDLWVNIEGSPDFLDAWA
                     DWRRADPDRMFVLNVPMLERNEERVPDDEVRTLLRAGAAGDYDQHFTRLAERLVELGVP
                     DTVIVLGWEMNGTTYTHRCGPDPTSWKAYWERIVTAMRAVPGQEFRFDFTPSRGRDAVP
                     WTECYPGDDVVDIIGMDSYDQPPGETFDDQVTDPYGLQKHVDFAAERGKPISFPEWGLF
                     RNGDNPEYMRRMLEWIDRHEPLYQTVTDYCPHGVWQCGSNPRSSEVFRTMMTEMAAPAA
                     PSPSPTPTPPPTPTAPVPTPTDPAPSPTLTPSAQPSPPVAPTPPAPGAEPPPARRWCVT
                     VPSVDWLGAWLREREICFRF"
     gene            complement(3479..4768)
                     /locus_tag="CCZ36_RS32615"
     CDS             complement(3479..4768)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964393.1"
                     /locus_tag="CCZ36_RS32615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_128819190.1"
                     /sec_met_domain="p450 (E-value: 1.6e-17, bitscore: 62.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPYQPSGDRVLRAADVDLADPAFWRLPRPERLRAFALLRELEA
                     PVLFTPRPGTARTAGKPFYALVRHADVRTASRTPAVFASAPGVTTPEPAGWAKALFGNS
                     MVNMDGSEHAALRRTISRRFTPRLLAGVEENVERLAGRLVDELIAERPGDFVPSAASRL
                     PLEVICDLMGVPKAYRARIAEQIDHASEHVGVERRGRARIRVPGRGLASLARMQWVMGR
                     LAAERRRRPGDDLVSALVCADIDGEALSGRQLGAFFSLLLVAGVETTRNAIAHGLFLLD
                     RHPDQRELLRSDFDRYIGGAVDEIVRHSTPIIQFRRTVTSECTLGGPTFLPGEKVALIY
                     ASANRDEAVFTHPDRFDITRSPNPHLGYGGGGPHHCLGAHLARLEMTALFRELIDRRPV
                     MRDLGDPELVDSNFDNRVGSLPFTFGPTFT"
     misc_feature    complement(4652..4654)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5001..5477
                     /locus_tag="CCZ36_RS32620"
     CDS             5001..5477
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042438 - melanin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955806.1"
                     /locus_tag="CCZ36_RS32620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosinase family oxidase copper chaperone"
                     /protein_id="WP_128819191.1"
                     /sec_met_domain="melC (E-value: 4.4e-48, bitscore: 161.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTPAKPGGTRIPSRRTVLRGAFTAAVVTGTAGALLPLVDHDPA
                     AAARPAPAPGPGSGSRATTEEFAEMYRGREIRGTATVVVPAGAPADDRVAVAAEPATEI
                     RIDGRPLHVMRRADGTYLSDVRHYESYPTLLETARAAVDELGTARLAPPAAHHM"
     gene            5497..6360
                     /locus_tag="CCZ36_RS32625"
     CDS             5497..6360
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955807.1"
                     /locus_tag="CCZ36_RS32625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosinase family protein"
                     /protein_id="WP_128819192.1"
                     /transl_table=11
                     /translation="MYTRKNQRDLTRTEKRRLIDAILKLKRSGRYDDFVVMHREYYVMD
                     TERRPRPAHMTSSFFPWHRQYLLEFEKALQRVDAGVSVPYWDWTQDNRPTSSLWAEDFL
                     GGNGRPGDRRVTTGPFAYAAGNWSVGRGVTDEHYLTRNFGRPGSAPVSLPTKNDLARAL
                     EDPVYDTAPWNSVSTEGFRNRVEGWGIRGVRTVGLHNRVHQWVGGPMAGAASPEDPVFW
                     LHHSFIDLLWDRWRKAHPKSAYRPGRKPASPGPDRDYVFGLDEAMPPWGVTPRKLLDHS
                     KIYRYA"
     gene            complement(6428..6709)
                     /locus_tag="CCZ36_RS32630"
     CDS             complement(6428..6709)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512958.1"
                     /locus_tag="CCZ36_RS32630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chaplin"
                     /protein_id="WP_069736030.1"
                     /transl_table=11
                     /translation="MSRMTKVAAVMAGTGALIAGGAGMASADAGAQALAAGSPGVGSGN
                     VVQVPVHVPVNLCGNTINVIGLLNPAFGNTCANVSGGHDNGGDYGYGR"
     cand_cluster    6773..27822
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    6773..27822
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[16772:17822](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(16773..17822)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            complement(6849..7997)
                     /locus_tag="CCZ36_RS32635"
     CDS             complement(6849..7997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955809.1"
                     /locus_tag="CCZ36_RS32635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_069736029.1"
                     /transl_table=11
                     /translation="MTAHRTGGLVVTLCRDFREFGALAGEWDALHRRCATPTPFQSHAW
                     LHSWWISYGQEGRLRVLLVRRAGRLIGAAPLMLVHRPMPLLVPMGGAVSDFFDILLDQE
                     EAGYAVGALGRGLDRAARHTVVDLREVRPDASAQLLFGRWPGARSRLTDSTCMELPAEP
                     LEDRVARQTGSRGQRLRSKLRKVDALGVETHRVPQDGVPAAIGTLLRLHERQWEGRTVN
                     PEHLRARFSDHLIRSVGRMVGDGTAAMTEFRLNGEVVASNLSLQSGRLTGGYLYGADPA
                     LRERKVDVSTMLLREVAQQASDGGRAVLSLLRGAESYKNHWGPVPVVNQRLLLARPGLE
                     PLLRLRESQVAVRERAVETVKARFPAARDWHERLSGLPVIGR"
     gene            complement(7994..8665)
                     /locus_tag="CCZ36_RS32640"
     CDS             complement(7994..8665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377858.1"
                     /locus_tag="CCZ36_RS32640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="WP_069736028.1"
                     /transl_table=11
                     /translation="MTDSPEQRRRVVVRRLRTALTRLPHWWPLPVSVLIGAASGLSYGA
                     LATPQYEATSYAMAVAEGDTDPAAALGYAQSYGRLTTSDATLSYAQGAAGEPVRALRSH
                     VTSETSPDSPMIAVTGTSSDRHKAADIANAVIEAVIVSSGHVSKDTGVKLIKFTHAMTP
                     DQPVSPSVPLGAAVGAAAGGLLGGLVLLVRPRREGWNVAAQVPGPAAGDGLAQDDRELV
                     R"
     gene            complement(8662..9798)
                     /locus_tag="CCZ36_RS32645"
     CDS             complement(8662..9798)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487589.1"
                     /locus_tag="CCZ36_RS32645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_128819193.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.5e-22,
                     bitscore: 78.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALHVITGLGVGGAERQLRLLLRHLPVECDVVTLTNPGAVAEEL
                     RSDGIRVTHLGMRGNRDLSAVGRLARLIRDGRYDLVHTHLYRACVYGRIAARLAGTRAT
                     VATEHSLGRAEIEGRPLTRSIRALYLSTERLGAATVAVSSTVAGRLRDWGVPADRIRLV
                     PNGIDADRFRFDGERRASVRAALGIPEDGFVVGGVGRLVPGKRFDVLIRAVAALPEARL
                     LLAGDGPEAGALRALALRLGAVDRIRFLGECDEDGEGPVPGVPALLSALDVFVSTSREE
                     SFGLAAVEALAAGLPVLHDACPAIDDLPAAHAPGATRIAGSPEELADRLRQRIQARPDR
                     RPPPRAVGHYDIRRSSERLMDVYAYALDTAPPNRRAHS"
     gene            complement(9795..10607)
                     /locus_tag="CCZ36_RS32650"
     CDS             complement(9795..10607)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129293.1"
                     /locus_tag="CCZ36_RS32650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_069741721.1"
                     /transl_table=11
                     /translation="MAAESSAHCADAPSSRLRPHTRRQPWILTYHSVTDPSDDPYGITV
                     SPERLDEQLSWLRSRRLTGVGVSELLRAGASGRRGLVGLTFDDGYADFLDEALPVLRKH
                     GCRATVFVLPGRPGGVNEWDPLGPRKPLLTHDDVRRVAAAGMEVGSHGLYHQDLTGLSD
                     GELRRETADSRELIGDLTGSLPEGFCYPYGILDRRVTRAARRAGYGYACALTPGPLLSR
                     FALPRTHISQADRGVRLWAKDLRHGLRQVAVPGAGSGRAVPVRAGGPR"
     gene            complement(10597..12324)
                     /locus_tag="CCZ36_RS32655"
     CDS             complement(10597..12324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129294.1"
                     /locus_tag="CCZ36_RS32655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lipid II flippase MurJ"
                     /protein_id="WP_128819194.1"
                     /transl_table=11
                     /translation="MSESGTGTEAEARPADAATGPSLLPAPGSGPEGPEGPRPPGGSSG
                     AASGEAPRLGAFLARAAAGTAVLTVLAAVLGLVRDQAIARYFGASDASDAFLIAWTVPE
                     MAATLLIEDGMALLLVPAFSLALTRRASGGTEGGADPVRDLVAATLPRLFLLLSGGAAL
                     LVAGAPWVVGVLAPGLADPRLAVDCTRLTAVTVLTFGITGYFSAALRAHGSFLPPAGVY
                     VAYNLGIIGMTLALHAAWGVRAAAAGVAVGSALMILTQLPVFLRLVPLARPRLPRFGRL
                     GRRAARSAPLLGFAVLAPVVVFVVSRQSQVLVERFLASTLPSGAISHLNYAQKVAQMPM
                     VLSLMICTVTFPVVAQAMAAGEHEKARRRVERDLGLAGLVVLLGTAVVLGYAPQIVEVL
                     FQRGAFDAADTASTAQVMRVYALGLLGHCLVGALSRPFFSSGRPTWFPAFAMGTGLLVT
                     MGAGYALTYRFGVDGIATANAIGISSTALLLLMGLGTRVVPIRARDVALSLGRLAGASL
                     AAGAAGWACAPLVPDPVLSLAAGCLLVPAVFFLTGLALRSPEVVSLLALIRRRFLDGR"
     gene            complement(12321..13679)
                     /locus_tag="CCZ36_RS32660"
     CDS             complement(12321..13679)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059095.1"
                     /locus_tag="CCZ36_RS32660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="O-antigen ligase family protein"
                     /protein_id="WP_128819195.1"
                     /sec_met_domain="Wzy_C (E-value: 8.9e-13, bitscore: 47.2,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVLTPPVPSPAAGPRAAARSPRAAWRGRWPLLPLVATVLLPAL
                     PYGTSGGGGPADVASGIAVLVCVGRLLYLRQRPLSAGAALVLGLPAVGFAVATVTAADP
                     AAALPGLGRYLQVFVLVPAAVFLLLRDACGFRIVAGALVLLAVVQGVAGVHQYVTGTGA
                     SYMGEDIRAVGTFGPSDIMGMATVVAYGLLAAAACALRTPGSAPAWLRPSAAVLAVALV
                     VPLTLSFSRGVWIATAAAVLVALALSGRRQALTSLAVLGAAGVVLVGGFGIGSEMIGDR
                     AASVTRVTSTPDRSVSDRYAMWSAAGAMWRERPATGVGLKGFPDHRDGRASIGLSSGSD
                     TAGAGQEFRRQALLSPHNMYLLVLGEQGLFGLTALVGSWAAILAGAVRRLWLARSRAHA
                     ALDCGLVAVALMTWQSVNFLYADIGGPTTVLSGVVLGLAAWWALAEPDRVSGA"
     gene            complement(13682..15007)
                     /locus_tag="CCZ36_RS32665"
     CDS             complement(13682..15007)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452705.1"
                     /locus_tag="CCZ36_RS32665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar transferase"
                     /protein_id="WP_234427981.1"
                     /sec_met_domain="Bac_transf (E-value: 2.5e-62, bitscore:
                     208.2, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALAPAVTFALVVPVAWPWLLMAVQAVAQVLLFARRGLYRMRLS
                     PSVLSDLPALLGLTLLQWYVTMEVLDVWAPQQGFGWAVLAYGAGTQTALTCVGRAAVYR
                     ARRRAAVRRPQSTLVVGQGAPARQVAAALYDHPAYGLRPVGLVAAPAAGDEQRVTGADA
                     VPLPVLASYQEVGRAVVQNSVRHAVFTAPPEATPDGAALFTLLAGHGCRVWLITGPGAV
                     AAPPAGGRPDHLWGFTAQPLRDGTDRPLGHGVKRAMDAVLAAVGLVVAAPVMAACALAV
                     RLSDGPGVIFRQERVGRHGRPFVLLKFRTLRPADVQESATRWNVASDGRLSRVGRMLRR
                     TSLDELPQLWNVLRGDMSMVGPRPERPFFVAQFSRAHPGYQARHRMPVGITGLAQVNGL
                     RGDTSIEERARFDNHYIETWSLWQDACVLARTAGSLFRLGGS"
     gene            complement(15160..16326)
                     /locus_tag="CCZ36_RS32670"
     CDS             complement(15160..16326)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377853.1"
                     /locus_tag="CCZ36_RS32670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_069736056.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1e-31, bitscore:
                     108.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTRERQLTVLHVVQPVDGGVARVVTDLVRAQAGAGLRPVVACP
                     PGSPLAVGAAAAGAEVHGWSATRSPGPRLAGEVAAARRIVRASRPHVVHAHSAKAGLAG
                     RIAVRGRVPTVFQPHAWSFEAVGGRTAELALGWERFGARWADHILCVSESERRTGQEAG
                     IAARWSVIHNGIDLDRFRPADHTVRAEARATLPLLQGTDPDAPLVVCVGRLTRQKGQDI
                     LLRAWRRMALPGARLVLVGDGPDRDGLAESAPPGVLFTGACEDVRPWIHAADVLVLPSR
                     WEGMALAPLEAMACGRAVVLTDVNGARESLPPGDEDHCLVPPEDPAALAAALTALLTDP
                     DLREAVSRRALRHTRAAFDVRRTAGAVAGLYQELVGMSGPTTRKRTER"
     gene            complement(16773..17822)
                     /locus_tag="CCZ36_RS32675"
     CDS             complement(16773..17822)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377851.1"
                     /locus_tag="CCZ36_RS32675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_128819196.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.8e-59, bitscore:
                     197.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSTTRRASAPQILDRCRELVRPALVASVGRLHPWHAEAAAFSL
                     GWRGADGEPVPGSQGKGVRQALAVLGAEAAGGSGEDGLLGAVAVELIHTFSLIHDDIMD
                     GDETRRRRPTLWKAYGTGPAVLAGDALFALAVSTLAEAPGPGGPAAVRHLAGALGDLVH
                     GQAQDLLFESRPWSGPGAVLPHEYRAMATHKTGSLLGCAAALGAVLAGAPASTAEALDL
                     AGRHVGVAFQAVDDLLGIWGDPQVTGKPVHSDLRRFKKTYPVLAALSADHPAAGRLDAL
                     LTSAGPLDDAAARRAAELIDEAGGRRAAVTEAQEHLAAARACLDRVPLADEAKRDLLTL
                     IPYLVDRTG"
     gene            complement(17819..18877)
                     /locus_tag="CCZ36_RS32680"
     CDS             complement(17819..18877)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129300.1"
                     /locus_tag="CCZ36_RS32680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_128819197.1"
                     /transl_table=11
                     /translation="MQTKALAPEYQGALTKMSVNASLTDVLAEGVRHLRQAELSGSQEE
                     VARSGLAVAEAHRRLGQVAEADRAWKASYRAARSAGNTGAMAWALWSGGTLARQRGALR
                     LAFRLLSLAAELGKRGGDVVARGYSLAGLAETGRIQGDYATVATLHEQLLAEARARGEA
                     RHTVWALEGIAQIHRNTGSLDTALEMFEEAAVLAGDADDRRGRAWALRGIADIVSLRDG
                     ATGRALDLLAEAEVTCREMNLSSALAYNHKMRANVLFRAGRYEEARTVYEQALGEFRAM
                     DEPRGEALASLGLVKARARLGRDRHATAADLDELRGRLSRIGLLNAREMVEKAYAELGV
                     EPSSAGAGDDRR"
     gene            complement(19098..19757)
                     /locus_tag="CCZ36_RS32685"
     CDS             complement(19098..19757)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129301.1"
                     /locus_tag="CCZ36_RS32685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_128819198.1"
                     /transl_table=11
                     /translation="MTAGATGTDTRTKLLEGALRTLAEHGIAKTSARSVAASAGVNQAL
                     VFYHFGSVDELLAAACRYGAEQRVARHRDRLAAVTTLAELLRCGRELHEEERAGGHVAF
                     LAQVLAGAQTQPRLAPATAAGLDLWTAEIEKALVRILADSPLGEFTDPVGLARAVTGAF
                     VGLEMYEGVDPKGAERAFEALEHLAALAGVLDELGPVARRAVRHRLRRTERVQGGA"
     gene            complement(19754..20434)
                     /locus_tag="CCZ36_RS32690"
     CDS             complement(19754..20434)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059104.1"
                     /locus_tag="CCZ36_RS32690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4166 domain-containing protein"
                     /protein_id="WP_069736019.1"
                     /transl_table=11
                     /translation="MTSIFARAMGDDFARLHPRLQRRFSVGLESGEACVGRGSMDRIWH
                     GRAFVKPFLALGATRNILVPRTGRDVPFTIENVPYTDSHGRETVTFVRTFALPGGARRF
                     DATMVHSPERSCVLDYLGTHQHLATDLRLTAEPDGSLLIRSGEHRFREGPLDLRVPDLI
                     GGDAEVRESFDDATGRFRIRVTVTNRRFGPLFGYEGTFRVRYVDALRHGVRAGLRPVRE
                     EARA"
     gene            complement(20431..21123)
                     /locus_tag="CCZ36_RS32695"
     CDS             complement(20431..21123)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059105.1"
                     /locus_tag="CCZ36_RS32695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128819199.1"
                     /transl_table=11
                     /translation="MGLYIEALIRTDPDRLWARTQDPAQHQRWDLRFTEIRPLPGPAGS
                     AQRFRYATRVLPFLTVAGTGTSAGERERADGERVSALRFASPERLSLLAEGSGYWRYVP
                     TADGIRFLTGYDYRTRWGRFGAVADRLVFRPLMGWATAWSFDRLRLWCERDISPARSLA
                     HALVEVLVRLLLVAAALPFGPAAVLPAALAALLAPPSSLTPAARRCLRRPPGRPAAAPS
                     LLARLERP"
     misc_feature    complement(21201..21216)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            complement(21238..22137)
                     /locus_tag="CCZ36_RS32700"
     CDS             complement(21238..22137)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129304.1"
                     /locus_tag="CCZ36_RS32700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase/quinone reductase family protein"
                     /protein_id="WP_128819200.1"
                     /transl_table=11
                     /translation="MPQTFQQSVITEFRANAGKVGGPFAGTDLLLLTTTGARSGKPHTT
                     PLGYVRDARRLLVVASNLGAPLHPDWYRNLLAHPTVQVELGDEAFESLAVPAEGARRDE
                     LFARVVAEAPGYAEYQDATDRVLPVVVLELPDPDAAAPPVTSLADKLVEVHTWLRGQLR
                     HVHDETEVYFAARAGYGGVGEPPAPGLGLQIRQRCLAFCQALEFHHTAEDGHMFPTMEG
                     HHPHLRDVFDRLREEHRSIAAVQAALAALLADAAITEPDRFRAELARMTEELTAHLDHE
                     EKHILPLLAEVPWPPATA"
     gene            22525..22824
                     /locus_tag="CCZ36_RS32705"
     CDS             22525..22824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955824.1"
                     /locus_tag="CCZ36_RS32705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2087 domain-containing protein"
                     /protein_id="WP_128819201.1"
                     /transl_table=11
                     /translation="MPTQQKTPAPLPPTPRTHPVEALFSHGRLVAIPRKEARREQLLTH
                     LADTLFERERSYTEREVNEALLTVHEDCSALRRYLVVAGLLVRPRDGSSYRRGR"
     gene            complement(22864..>23025)
                     /locus_tag="CCZ36_RS36150"
                     /pseudo=""
     CDS             complement(22864..>23025)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948267.1"
                     /locus_tag="CCZ36_RS36150"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LQLGNIVIPKSVTPERIRQNIDVFDFELSAADMDAVAALDRGLRT
                     GPDPDTLN"
     misc_feature    23108..23125
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.2"
                     /tool="antismash"
     gene            23364..24659
                     /locus_tag="CCZ36_RS32715"
     CDS             23364..24659
                     /NRPS_PKS="Domain: Abhydrolase_1 (47-220). E-value:
                     5.8e-19. Score: 60.6. Matches aSDomain:
                     nrpspksdomains_CCZ36_RS32715_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129307.1"
                     /locus_tag="CCZ36_RS32715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_128819202.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-17, bitscore: 63.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSYRQPGVVLTDRRFTVPLDHSDPAGEQIEVYGREAVAASRAGE
                     ELPWLVYLEGGPGFGARRFVGTEAWLGRALREFRVLLLDQRGTGLSTPANRQTLPLRGG
                     PREQAGYLAHFRADSIVRDCELIRQRLTGGAPWTVLGQSFGGFCAVRYLSAAPEGLKEV
                     LITGGLPSLDAHADDVYRAAYPRIERKVAAHYARYPQDVERARAIAAHLAQHRPEYAGH
                     RLTPEGFQSLGIMLGSGSGGHQLHYLLENAFVRTPHGTELSDTFQEAMRTAVSFAGHPL
                     YALLHEAIYGQGERATDWAAERVRGEFPQFDAATALKGDGPLLFTGETIHPWHFDVDPA
                     LRPLRETAELLARRTDWPVLYDPERLAANEVPVAAAVYHDDMYVDTADSLRTAAAIRGL
                     RTWVTNEYEHDGVRAGGPRVLDRLLSLVRDEA"
     aSDomain        23505..24023
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CCZ36_RS32715_Abhydrolase_1.1"
                     /evalue="5.80E-19"
                     /label="CCZ36_RS32715_Abhydrolase_1.1"
                     /locus_tag="CCZ36_RS32715"
                     /protein_end="220"
                     /protein_start="47"
                     /score="60.6"
                     /tool="antismash"
                     /translation="PWLVYLEGGPGFGARRFVGTEAWLGRALREFRVLLLDQRGTGLST
                     PANRQTLPLRGGPREQAGYLAHFRADSIVRDCELIRQRLTGGAPWTVLGQSFGGFCAVR
                     YLSAAPEGLKEVLITGGLPSLDAHADDVYRAAYPRIERKVAAHYARYPQDVERARAIAA
                     HLAQHRPEYA"
     gene            complement(24670..25242)
                     /locus_tag="CCZ36_RS32720"
     CDS             complement(24670..25242)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129308.1"
                     /locus_tag="CCZ36_RS32720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_069736014.1"
                     /transl_table=11
                     /translation="MPTPASLSPAQAAARLEEFTVIDVRAPGEYAAGHVPGALNIPLDK
                     LPDALPALKSASARGSLLVVCASGVRSTRACEILAGADIEAVTLTGGTSAWEGDGRGLD
                     RPEGARTTWAMERQVRLAAGSLVVAGLVAGIRFPAARWLSAGVGTGLVYSALSNTCGMA
                     AVLSKLPHNRAPRAAGDLDATLEELQR"
     gene            25316..26049
                     /locus_tag="CCZ36_RS32725"
                     /pseudo=""
     CDS             25316..26049
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006129309.1"
                     /locus_tag="CCZ36_RS32725"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PIG-L deacetylase family protein"
                     /pseudo=""
                     /sec_met_domain="PIG-L (E-value: 3.7e-20, bitscore: 71.6,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPQRLEPMPGDWQRALAVVAHPDDLEYGAAAAVAEWTDGGREVV
                     YLLASRGEAGIDTLPPEECAPVREREQRASAAVVGVRTVEFLDHRDGVIEYGTGLRRDI
                     AAAIRRHRPELVVTLNHRDTWGGPPGTPPTTARSGAPPSTPSPTQATAGSSPTWTSRDS
                     SRGRGCAGSPWRAATGPPTRSTRRPASNARSARCWNTVRTSRR"
     gene            26128..26727
                     /locus_tag="CCZ36_RS32730"
     CDS             26128..26727
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765474.1"
                     /locus_tag="CCZ36_RS32730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_069736012.1"
                     /transl_table=11
                     /translation="MKERDRDDPELESVLSGVGPRLRRLRKDRGVTLAALSAATGISVS
                     TLSRLESGGRRPSLELMLPIARAHEVPLDDLVGAAPVGDPRVRAKPIVQHGRTMLPLTA
                     RPGGLQAYKLIQEPGSGGPPEQRTHEGYEWLFVLSGKLRLLLAEHDLVLEPGEAAEFDT
                     RLPHWFGPAGDETVEFLSLFGPQGERMHVRAKPRRG"
     misc_feature    complement(26762..26776)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.76"
                     /tool="antismash"
ORIGIN
        1 ggcagcccgc cgagcccgag cggcggcccg gagggaaggt cggggaaggt gaccgacccg
       61 tccggtgtga cgaccaccgg cggggggtgg cccgcccgcg ccatcgtgca ggagccgttc
      121 gtcggatcgt agacggcgta cagacaggtc gcccccacca ccgtcgagcc gccccgctcc
      181 gccgggcccc ccgtgcgctc ctcctcgctg agccgcagca cgagatcgtc caggcgggcc
      241 agcagctcgt ccggcggcag atccatgtcg gccagtgtct gtacggcggt acgcagccgg
      301 cccatggtcg cggcggcccc gatgccgtgc ccgacgacat cgccgatgac caggccgacc
      361 cgggcgccgg acagcgggat cacgtcgaac cagtccccgc cgaccccgtc cttcgcgtcc
      421 gccgggaggt acgaccacgc cacgtccagc gccgtcccgc cccgcagtgt ctgcggcagc
      481 aggctccgct ggagcaccag tgccgcggtg tgctcccggg tgtagcggcg ggcgttgtcc
      541 acgcacacgg cggcccgtgc cacgagctcc cgggcgggcg ccacgtcgtc ctcgtcgaac
      601 ggcaccgggt tctgggaccg catgaaggtg gtcagtccca gcacggtgtc gcgggcccgc
      661 atcggtacgg agatcaacga gtgcagcccg aactcccgga tccgggcggc ccgctccggc
      721 tgctccaccg cccacccctg gctgtccggg tcgagcaccg gcagcagaac gggggcgccc
      781 gacagcagga aatccgcgtc gtgcggcggc ggcacgaagt ccaccgcctc accgacccgg
      841 acgaccgcct ccgggcagcc ctcccgcacc gagctcatgc ccgcccggcg catggccggc
      901 cgctcgccct cggccggtgt ggccgacccg ggccggtcac cgccgaacgg ggcctccagc
      961 aggtcgacga agacgaagtc cgcgaaccgg ggcaccgcga agtcggcgag ttcctgcgcc
     1021 gtacgctgta cgtccagggt ggagccgatg ctcgccccgg cctcgttgac cagcgcgagc
     1081 agccgacgcg cgttccaccg gtcggtgacg tcgcggacca tgtagccgat gccgatccgc
     1141 cggtcctggg cgtcggccag cgggaagaac gagctggcgt acgcgcgtcg gcggtgcgga
     1201 tcggaccagc tccagcccag gtactcgtaa tccgtgacgg cctcgcccgt cgagaggacc
     1261 tgccgcatca gccgctcgat gggggccgcc agcgcactgg gcagcacatc ggccggccgg
     1321 cgccccagac gctgttcccg cggcacgccg ccgaaccgct ccagggtgtc gttgagccag
     1381 agatagcgca ggcccgggtc gagcacggcc atcccgaccg gggaccgggc catgaagtcg
     1441 tccagcacgg acccgctcat cgtccagtgc ggagtgagct cccgcccgga caccaggaag
     1501 acctcccgcc cggcgatccg gaaggaggag gtgacccgca catcgatgtc gagggaccgg
     1561 ccgtcccggc cccgcaggga gaccagcccg ctccatgccg acccggtccg gcagcgcgcg
     1621 gcaacggcgg ccgtccggcg cgggtcgggc gggccggtca gcaggcgggc ggccgaccgg
     1681 ccgatcacct cggccgccgg atacccgagc agcgcctcgg ccccgcgggt ccagccgatg
     1741 accgtgccgt ccccggcgag caccgcggcc gcgtcgtcgg ccgcccgagc cgggccccgc
     1801 ccgtccccgg agggcagcgg gccgggctcc gccgggaagc cctcatcggc ggatgccatt
     1861 gcacctcacc accctctgta ggtttccatg gtcgcgcgtc gctccgtacc gcgcccggcg
     1921 tggcatacga gggaggcgcg cgagccgtcc ctcgttcggc ggcgtgacgg agcgggacgt
     1981 gcccgcgttg gtgggatgac aagcggttgc tcgtcccccc gcccccgcgc cggacctgtg
     2041 tgggtggacg gctccggccc cgtcacgagg gccggagccg tttccatgcc cggggtcaga
     2101 agcggaagca gatctcgcgc tcccgcagcc acgcgcccag ccagtcgacg gacggcacgg
     2161 tgacgcacca cctgcgggcc ggcgggggct cggccccggg cgccgggggc gtgggcgcca
     2221 ccggcgggga cggctgcgcg gagggcgtga gcgtcgggga cggggccggg tcggtcggcg
     2281 tcgggaccgg ggccgtcggc gtcggcgggg gagtcggcgt cgggctgggg gacggcgcgg
     2341 cgggcgcggc catctccgtc atcatcgtcc ggaacacctc cgaggagcgc ggattgctcc
     2401 cgcactgcca gacaccgtgc gggcagtagt ccgtgaccgt ctggtagagc ggctcgtgcc
     2461 ggtcgatcca ctccagcatg cgccgcatgt actcggggtt gtcgccgttg cggaagagcc
     2521 cccactccgg gaacgagatg ggtttgccgc gctccgcggc gaagtcgacg tgcttctgga
     2581 gcccgtacgg gtcggtgacc tggtcgtcga aggtctcgcc gggaggctgg tcgtaggagt
     2641 ccatcccgat gatgtcgacg acgtcgtcgc ccggatagca ctcggtccac ggcaccgcgt
     2701 cccgcccacg gctcggggtg aagtcgaagc ggaactcctg accgggcacc gcgcgcatcg
     2761 ccgtgacgat ccgctcccag taggccttcc aggacgtggg gtcggggccg caccggtgcg
     2821 tgtacgtggt gccgttcatc tcccagccca gcacgatcac ggtgtccggg acgcccagct
     2881 ccaccaggcg ttccgccagc cgggtgaagt gctggtcgta gtcgcccgcc gctcccgccc
     2941 ggagcagggt gcggacctcg tcgtccggga cccgctcctc gttgcgctcc agcatcggta
     3001 cgttcaggac gaacatccgg tcggggtccg cccgtctcca gtccgcccag gcgtcgagga
     3061 agtcggggga gccctcgatg ttgacccaca gatcgcccgg cagatacgtg tgccccaccc
     3121 gcagctccgc cccgcccagc cagcgcgaga agtcggccat ccgactgacc ccttcgggcc
     3181 cgtagtccag atacgccccg tgcgccgtag cgctacccgc cctcggccca ccgggtgccg
     3241 cgccgtcgac ggaatcggtg cccggaggcg actgacccgc gataccgcca cccgccagaa
     3301 ggctgagagc aagcgccgcg atgcacgaaa cgaagagacg gcgctttgcc ggcattgctc
     3361 ctcctggctg tgatgaattc cggcccgtcc ggcccggtgg ggagagagtt tcatcatcat
     3421 gccccggtgg catgcggggg gagtccattt atcgtattcg gcgttgcggg cgtgccgttc
     3481 aggtgaatgt ggggccgaac gtgaacggca gagagccgac gcggttgtcg aaattcgaat
     3541 cgaccagttc cgggtccccc agatcccgca tgacgggacg tcggtcgatc agttcccgga
     3601 acagggccgt catttccaga cgggccagat gcgctcccag gcagtggtgc gggcccccgc
     3661 cgccgtatcc cagatgggga ttgggcgagc gagtgatgtc gaagcgatcc ggatgggtga
     3721 aaaccgcctc gtcgcgattg gcggacgcgt aaatgagtgc gactttctcg cccgggagga
     3781 atgtgggacc gcccagcgtg cattcgctgg tgacggtcct gcggaactgg atgatcggag
     3841 tcgaatgccg cacgatctcg tcgacggccc cgccgatgta ccggtcgaag tcggaccgca
     3901 gcagctcccg ctggtccgga tgccggtcga gcaggaacag cccgtgcgcg atggcgttgc
     3961 gcgtggtctc caccccggcc accagcagca gcgagaagaa ggcccccaac tgccgccccg
     4021 acagggcctc gccgtcgatg tccgcacata cgagcgccga gacgaggtcg tcccccgggc
     4081 gacggcggcg ctccgccgcg agccgcccca tgacccactg catccgggcc agggacgcca
     4141 gcccccgccc ggggacccgg atccgggccc ggccccgccg ctcgacgccg acatgctccg
     4201 acgcgtggtc gatctgctcg gcgatccgcg cccggtacgc cttcgggacg cccatcaggt
     4261 cgcagatcac ctccaacggc agccgcgagg ccgccgacgg cacgaagtcc ccgggccgct
     4321 cggcgatcag ctcgtccacc agccgcccgg cgagccgctc gacgttctcc tcgacacccg
     4381 ccagcagccg gggggtgaac cgccgcgaga tggtccggcg cagcgccgcg tgctcggacc
     4441 cgtccatgtt gaccatcgag ttcccgaaca gcgcctttgc ccagccggcc ggttccggag
     4501 tggtgacccc gggagcgctg gcgaacacgg cgggcgtacg gctcgcggtc cgcacgtcgg
     4561 catggcgcac cagggcgtag aagggctttc cggccgtacg cgcggtaccg ggccggggcg
     4621 tgaacagcac cggcgcctcc agctctcgca gtaaggcgaa ggccctgagc cgctccgggc
     4681 gcggcagccg ccagaacgcc gggtcggcca gatcgacgtc cgccgcgcgc agcacacggt
     4741 ccccggacgg ctggtacgga acggtcatac ccaccacctc cacggttcga caggccatgt
     4801 tccggtccgc cggccacggc aggccccgcg acgcggcccg ccgccgccga tcgccccgca
     4861 ccctcacgcg tttgccggaa cgcgaccgcc gcgtgtgcgc cgtacgccgc acgcacgaga
     4921 actgtttcgc caccacctcg ttgtcaacat cgccatcaga agcacctcgg acgagttaac
     4981 gagaggcagg tagtcatctc atgagcccca cccccgcgaa accgggcggc acccgcatcc
     5041 cctcccgccg caccgtcctg cgcggagcct tcaccgccgc cgtggtcacg ggcaccgccg
     5101 gcgccctgct cccgctggtc gaccacgacc cggccgcagc ggcccggccc gcaccggcgc
     5161 ccggacccgg ctccggctcc cgggccacga cggaggagtt cgccgagatg taccggggcc
     5221 gggagatccg ggggacggcg accgtcgtcg tccccgcggg cgccccggcc gacgaccggg
     5281 tcgcggtcgc cgccgaaccg gccaccgaga tccgtatcga cggcagaccg ctgcatgtca
     5341 tgaggcgggc ggacggcacc tatctgagcg acgtccggca ctacgagtcg tatccgacgc
     5401 tcctggagac ggcccgtgcc gccgtcgacg aactcggtac cgcccgactc gcaccgcccg
     5461 ccgcgcacca catgtgaacc aggaggacca gcaccggtgt acacccgcaa gaaccagcgc
     5521 gacctcacgc gcaccgagaa gcgccggctc atcgacgcga tcctgaaact gaagcgctcg
     5581 ggccgctacg acgacttcgt cgtcatgcac cgggagtact acgtcatgga caccgaacgc
     5641 cggccgcgcc cggcgcacat gacgtcctcg ttcttcccct ggcaccgcca gtacctgctg
     5701 gagttcgaga aggcgctcca gcgcgtcgac gccggcgtca gcgtccccta ctgggactgg
     5761 acccaggaca accggccgac ctcctcgctc tgggcggagg acttcctcgg cggcaacggc
     5821 aggcccggcg accgccgggt caccaccggc ccgttcgcct acgcggcggg caactggagc
     5881 gtcggcaggg gcgtcaccga cgagcactac ctcacccgca acttcggcag gccgggcagc
     5941 gccccggtat ccctgcccac caagaacgac ctggcgcggg ccctcgagga ccccgtctac
     6001 gacaccgcgc cctggaacag cgtcagcacc gagggcttcc gcaaccgcgt cgagggatgg
     6061 ggcatccggg gcgtacgcac ggtcggcctg cacaaccggg tgcaccagtg ggtcggcgga
     6121 ccgatggcgg gcgcggcctc ccccgaggac ccggtgttct ggctccacca ctccttcatc
     6181 gacctgctct gggaccgctg gcgcaaggcc catcccaagt ccgcctaccg gccgggccgc
     6241 aaacccgcct cgcccggccc ggaccgcgac tacgtcttcg gcctcgacga ggcgatgccc
     6301 ccctggggcg tgaccccgag gaagctcctc gaccacagca agatctaccg ctacgcctga
     6361 gggcggacgg aggaacggcc ggccccctcc gcacggaggg agccgaccgt tccggaaccg
     6421 cgggagatca gcggccgtag ccgtagtccc cgccgttgtc gtggccgccg gagacgttgg
     6481 cgcaggtgtt tccgaaggcc gggttcagca ggccgatcac gttgatcgtg ttgccgcaga
     6541 ggttcaccgg gacgtgcacg ggaacctgga cgacgttgcc cgaaccgacc ccgggggagc
     6601 cggcggcgag ggcctgcgca ccggcgtccg cggacgccat gccggcgccg ccggcgatca
     6661 gggcgccggt gccggccatc acagcggcga ccttcgtcat acgagacatg gagaactcct
     6721 tgtaaagaag ggggttgtgc tgcggacacg aagcccgcac cccctgacaa cgcgaaagac
     6781 gccggacggt aacggatctg cgcataggtg atatctccga cgccgccgtc cggcgtacgc
     6841 ccggcgtgtc agcgtccgat caccggcagc cccgacagcc gctcgtgcca gtcccgcgcc
     6901 gccgggaacc gggccttcac ggtctccacc gcccgctccc gcaccgccac ctgcgactcg
     6961 cgcagccgca gcagtggctc cagacccggc cgggccagca gcagccgctg attgaccacc
     7021 ggcaccggcc cccagtggtt cttgtagctc tccgcgccgc gcagcaggct cagcaccgcg
     7081 cgccccccgt ccgaggcctg ctgggcgacc tcgcgcagca gcatcgtcga cacatcgacc
     7141 ttccgttcgc gcagcgccgg gtccgccccg tacagatagc cgcccgtcaa ccgcccggac
     7201 tgcaacgaca ggttggacgc caccacctcg ccgttcagcc ggaactcggt catggccgcc
     7261 gtaccgtccc ccaccatccg tcccaccgac cggatcagat ggtccgagaa ccgcgcccgc
     7321 agatgctcgg ggttgaccgt ccggccctcc cactgccgct cgtgcagccg cagcagcgtg
     7381 ccgatcgcgg ccggcacccc gtcctgcgga acccggtgcg tctcgacgcc cagggcgtcg
     7441 accttgcgca gcttggagcg caggcgctgg ccgcgcgatc ccgtctgccg agccacacgg
     7501 tcctccagcg gctcggccgg cagttccatg cacgtcgagt ccgtgagccg gctccgggcc
     7561 cccggccacc gcccgaacag caactgcgcc gaagcgtccg gacggacctc ccgcaggtcc
     7621 accacggtgt gccgggccgc ccggtccaga ccgcgcccca gcgcccccac cgcgtacccg
     7681 gcctcctcct ggtccaggag gatgtcgaag aagtcggaga cggccccgcc catcgggacg
     7741 agcagcggca tcggacggtg caccagcatc aggggcgccg ccccgatcag ccgcccggcc
     7801 cggcggacca gcagtacccg cagccggccc tcctgaccgt acgagatcca ccacgagtgc
     7861 agccaggcgt ggctctggaa cggggtgggg gtggcgcagc ggcggtgcag cgcgtcccat
     7921 tcaccggcga gcgcgccgaa ctcccggaag tcccggcaca gcgtcacgac caggccgccc
     7981 gtccggtgcg ccgtcatcgg acgagctccc ggtcgtcctg ggcgaggccg tccccggccg
     8041 ccgggccggg cacctgggcc gcgacgttcc agccctcccg acggggacgc accagcagga
     8101 ccagaccgcc cagcagaccg cccgccgccg cccccacggc ggcgcccagc ggtaccgacg
     8161 gcgagaccgg ctggtccggc gtcatcgcat gggtgaactt gatcagcttg accccggtgt
     8221 ccttggagac atgaccgctg ctcacgatga cggcctcgat gaccgcgttg gcgatgtcgg
     8281 ccgccttgtg gcggtccgag gacgtccccg tcacggcgat catcggtgag tccggggagg
     8341 tctccgacgt cacgtgggac cgcagtgcgc gcaccggctc gcccgccgcg ccctgcgcgt
     8401 acgagagggt cgcgtcgctc gtcgtcagcc gcccgtacga ctgcgcgtac cccagcgccg
     8461 ccgcggggtc cgtgtcccct tccgcgaccg ccatcgcata actggtggcc tcgtactgcg
     8521 gggtggcgag cgcgccgtac gagagcccgg aggcggcccc gatcagcacg ctgacgggca
     8581 gcggccacca gtgcggcagc cgggtgaggg cggtgcgcag ccgacggacg acaacgcgtc
     8641 gccgctgctc gggtgagtcg gtcatgaatg agctctccgg ttcggtgggg cggtgtcgag
     8701 ggcgtacgcg tacacgtcca tcaggcgctc gctgctgcgc cggatgtcgt agtggccgac
     8761 ggcccggggc ggcggacggc ggtccgggcg ggcctgtatc cgctgccgca gccggtccgc
     8821 cagctcctcg gggctcccgg cgatccgggt cgcccccggg gcgtgggcgg cgggcaggtc
     8881 gtcgatggcg gggcaggcgt cgtggagcac cgggagtccg gcggcgagcg cctccacagc
     8941 ggccagtccg aaggactcct cgcgggacgt ggagacgaag acgtccaggg cactcagcag
     9001 cgccggaaca cccgggaccg gcccttcacc gtcctcgtcg cactccccga ggaaccggat
     9061 ccggtccacc gcccccaggc gcagggcgag cgcccgcagc gccccggcct ccggcccgtc
     9121 cccggccagc agcaaccggg cctccggcag ggcggcgacc gcgcggatca gcacgtcgaa
     9181 ccgcttgccc ggcaccagcc ggccgacccc gcccaccacg aacccgtcct cggggatgcc
     9241 cagggcggcc cgcacggatg cccgccgctc cccgtcgaag cggaaccggt ccgcgtcgat
     9301 gccgttgggc accagccgga tccggtcggc gggcaccccc cagtcccgca gtcgcccggc
     9361 caccgtggac gagacggcga cggtcgccgc gccgagccgc tcggtggaga ggtagagggc
     9421 gcggatggac cgggtgagcg gccggccctc gatctcggcc cgccccaggg agtgttcggt
     9481 cgccacggtc gctcgcgtcc ccgcgaggcg cgccgcgatc ctgccgtaca cacaggcccg
     9541 gtagaggtgc gtgtggacca ggtcgtagcg gccgtcgcgg atcagccggg cgaggcgtcc
     9601 gacggccgac aggtcccggt tgccgcgcat cccgaggtgc gtcacccgga tcccgtcgga
     9661 ccgcagctcc tcggccacgg cccccgggtt ggtgagcgtc accacgtcgc actccaccgg
     9721 cagatggcgc agcaacagcc gcaactgccg ctcggcgccg ccgaccccga gcccggtgat
     9781 gacgtgcagc gccctcaccg cggacccccc gcccgcaccg gcacggccct gccggaaccc
     9841 gcacccggca cggccacctg ccgcagcccg tgccgcaggt ccttcgccca cagccgcact
     9901 ccccggtccg cctggctgat gtgggtacgg ggcagggcga accggctgag cagcggaccg
     9961 ggcgtcagcg cgcacgcgta gccgtaaccc gcccggcgcg cggcccgggt gacccggcgg
    10021 tcgagaatgc cgtacgggta gcagaagccc tccgggagcg agccggtgag atcaccgatc
    10081 agctcccggc tgtcggcggt ctcgcggcgc agctccccgt ccgacagccc cgtcaggtcc
    10141 tggtggtaca gcccgtgcga gccgacctcc atgcccgcgg cggcgacccg ccggacgtcg
    10201 tcgtgggtga gcagcggctt gcgcgggccc agtgggtccc actcgttgac cccgcccgga
    10261 cggcccggca ggacgaacac cgtcgcccgg cagccgtgct tgcgcagcac cggcagcgcc
    10321 tcgtcgagga agtccgcgta cccgtcgtcg aaggtcagtc ccaccagccc gcgccgcccc
    10381 gacgcccccg cgcgcagcag ctccgacacg cccacccccg tcagccgccg gctgcgcagc
    10441 caggacaact gctcgtcgag gcgctcgggg gagaccgtga tgccgtacgg gtcgtcgctc
    10501 gggtccgtca ccgagtggta cgtgaggatc cacggctgac ggcgggtgtg cgggcggagc
    10561 cgggacgagg gagcgtcggc gcaatgtgcc gaggattcag cggccatcaa ggaacctccg
    10621 tcggatgagt gccagcaggg agacgacctc gggcgagcgc agggcgaggc cggtcaggaa
    10681 gaacacggcg gggacgagaa ggcacccggc ggccaggctc agcaccggat cggggacgag
    10741 cggggcgcac gcccagcccg ccgcgcccgc cgccagcgac gccccggcga gccggcccag
    10801 cgagagcgcc acgtcccggg ccctgatcgg cacgacccgg gtgccgaggc ccatcagcag
    10861 cagcagggcc gtggagctga tgccgatcgc gttggcggtc gcgatgccgt ccacaccgaa
    10921 gcggtacgtc agcgcgtagc cggcccccat cgtgaccagc agtccggtcc ccatcgcgaa
    10981 cgccgggaac caggtgggcc gcccggacga gaagaacggc cggctcagcg cgccgaccag
    11041 gcagtgcccc agcagcccca gcgcgtagac ccgcatgacc tgggcggtcg acgcggtgtc
    11101 ggcggcgtcg aacgcgccgc gctggaagag cacttcgacg atctggggtg cgtatccgag
    11161 gacgaccgcc gtgccgagca ggaccaccag ccccgccaga cccaggtccc gctcgacccg
    11221 ccgccgggcc ttctcgtgct ccccggcggc catggcctgc gcgacgaccg ggaaggtcac
    11281 cgtgcagatc atcagcgaca gcaccatcgg catctgcgcg accttctgcg cgtagttcag
    11341 atgcgagatc gccccggagg gcagggtgga ggccaggaac cgctccacca gcacctggga
    11401 ctgccggctc acgacgaaca cgaccacggg ggccagcacc gcgaacccca gcagcggagc
    11461 gctccgcgcc gcccgccgcc cgagccgtcc gaaccgtggc aggcgcggcc gggcgagcgg
    11521 taccagccgc aggaagacgg ggagctgggt gaggatcatc agcgcgctgc ccaccgcgac
    11581 ccccgccgcc gccgcccgta ccccccacgc cgcgtgcagg gccagcgtca tcccgatgat
    11641 gccgaggttg tacgcgacat agaccccggc gggcggcagg aagctgccgt gcgcgcgcag
    11701 ggcggcgctg aagtagccgg tgatcccgaa cgtgaggacg gtgaccgcgg tcagccgggt
    11761 gcagtccacc gcgagacggg gatcggcgag ccccggcgcc agcacgccca ccacccacgg
    11821 cgcgcccgcg acgagcagcg ccgcgccacc ggaaagcagg aggaacagcc gggggagcgt
    11881 ggccgccacc agatcccgta cggggtcggc gcctccctcc gtcccgccgg aggcacgacg
    11941 ggtgagggcg aggctgaacg ccgggacgag aagcagcgcc atcccgtcct cgatcagcag
    12001 cgtcgccgcc atctcgggca cggtccaggc gatcaggaac gcgtcgctgg cgtcgctcgc
    12061 cccgaagtac cgggcgatgg cctggtcccg caccagaccg aggacggccg ccagcacggt
    12121 cagtacagcc gtgcccgccg ccgcccgggc gaggaaggcc cccagccggg gcgcctcgcc
    12181 gctcgccgcc ccggatgagc cgccgggggg ccggggccct tcaggccctt caggccctga
    12241 ccccggggcc gggagcagcg aggggcccgt tgccgcgtcc gccggccgcg cctcggcctc
    12301 cgtgcccgta ccggactcgc tcatgcgccg ctcacccggt ccggctcggc cagcgcccac
    12361 caggctgcca gccccagcac gacaccgctg aggaccgtgg tgggaccgcc gatgtccgcg
    12421 tacaggaagt tgacgctctg ccaggtcatc agcgcgaccg ccaccagacc gcagtccagg
    12481 gccgcgtgcg cgcgggagcg ggcgagccac agccggcgga ccgcgccggc caggatcgcc
    12541 gcccagcttc cgacgagtgc ggtcagtccg aagaggccct gctcgccgag gacgaggagg
    12601 tacatgttgt gcggggagag gagggcctgg cggcggaact cctggcccgc gccggcggtg
    12661 tcgctgcccg acgagagccc gatcgaggcg cggccgtcac ggtggtcggg gaagcccttg
    12721 agaccgaccc cggtggccgg ccgctcgcgc cacatcgcgc ccgccgcact ccacatcgcg
    12781 tagcggtcgc tgaccgaccg gtccggggtg ctggtgacgc gggtcacgct ggcggcccgg
    12841 tccccgatca tctcggagcc gatgccgaac ccgccgacca ggaccacgcc cgccgcgccg
    12901 agcacggcca gcgaggtcag tgcctgccgc cgcccgctca gcgccagggc cacgagcacc
    12961 gcggcggccg tggcgatcca cacgccccgg ctgaacgaca gcgtcagcgg cacgaccagc
    13021 gcgacggcga ggacggcggc ggacggtcgt agccaggccg gggcgctccc gggcgtgcgc
    13081 agggcgcagg ccgccgcggc gagcagcccg taggcgacga cggtcgccat gcccatgatg
    13141 tcgctgggcc cgaaggtgcc gaccgcccgg atgtcctcgc ccatgtacga ggcgccggtc
    13201 ccggtgacgt actgatggac gcccgcgacg ccctggacga ccgccaggag gaccagcgca
    13261 ccggcgacga tccggaatcc gcaggcgtcc ctgagcagca ggaacaccgc ggccggcacc
    13321 aggacgaaga cctggaggta gcgcccgagc ccgggcagcg cggccgccgg gtccgccgcc
    13381 gtgaccgtgg ccaccgcgaa gcccaccgcg ggcaggccca ggaccagtgc ggcgccggcg
    13441 ctcaacggtc gctgccgcag atacagcagc cgccccacgc acaccagcac cgcgattccc
    13501 gaggccacat cggccggccc gcccccgccg gacgtcccgt aggggagggc gggcagcagg
    13561 acggtcgcga ccaacggcag cagcggccaa cggccacgcc aggcggcccg gggggagcgg
    13621 gccgcggcgc gcggcccggc cgccggtgac ggcacgggcg gggtcaggac agcggtcatg
    13681 gtcagctgcc tccgagccgg aacagggaac ccgccgtccg cgccagtacg cacgcgtcct
    13741 gccacagcga ccaggtctcg atgtagtggt tgtcgaagcg ggcccgctcc tcgatcgagg
    13801 tgtcgccgcg caacccgttc acctgggcca gccccgtgat gcccacgggc atccggtggc
    13861 gggcctggta gccggggtgg gcgcggctga actgcgccac gaagaagggc cgttcgggtc
    13921 gggggccgac catgctcatg tcgccgcgca ggacgttcca cagctgcggc agttcgtcga
    13981 gggacgtccg gcgcagcatg cggccgaccc ggctgagccg cccgtcggac gcgacgttcc
    14041 agcgggtggc cgactcctgg acgtcggcgg ggcgcagcgt gcggaacttc agcaggacga
    14101 aggggcgtcc gtgccggccg acgcgctcct gacggaagat cacacccggc ccgtcggaga
    14161 gccgcacggc gagcgcgcag gccgccatca ccggggccgc caccaccagt ccgaccgcgg
    14221 ccaggacggc gtccatcgcc cgcttcacgc cgtggccgag ggggcggtcc gttccatcgc
    14281 gcagcggctg ggcggtgaaa ccccacagat ggtcgggccg gccgcccgcc gggggcgccg
    14341 cgacggcgcc gggcccggtg atcagccaca cccggcagcc gtgcccggcg aggagggtga
    14401 agagggcggc gccgtccggg gtcgcctcgg gcggggccgt gaacaccgcg tgccgcacac
    14461 tgttctgcac caccgcccgt cccacctcct ggtacgaggc caggaccggc agcggcacgg
    14521 cgtcggcccc cgtcacccgc tgctcgtccc cggccgccgg ggcggcgacc agaccgaccg
    14581 gccgcagccc gtaggcgggg tggtcgtaca gcgcggccgc cacctgacgg gccggcgccc
    14641 cctggcccac gaccagcgtg gactgcgggc ggcggacggc ggcccgccgc cgcgcccggt
    14701 acaccgccgc gcgcccgacg caggtcagcg cggtctgcgt accggccccg tacgccagca
    14761 ccgcccagcc gaacccctgc tgcggggccc agacgtccag tacctccatg gtcacgtacc
    14821 actgaaggag ggtgagaccg aggagtgcgg gaaggtcgga gaggaccgag ggggacaacc
    14881 gcatccggta caggccgcgc cgggcgaaga gcagcacctg cgccaccgcc tgaacggcca
    14941 tcagcagcca gggccacgcg accgggacca ccagggcgaa cgtcaccgcc ggagccaggg
    15001 cgtccacgca cagcagcggg gcgggacggc cgtaccggac ggcccggcgc tgacccggcc
    15061 gtgcctgcgc accgccgccg cctcttcgcg gcggatgaac cgtgtgagcc tgcacggctg
    15121 ttgcctggcc ggctccggga accggtgcac tctccatcgt catcgctcgg tgcgcttcct
    15181 cgtcgtgggg ccggacatgc cgacaagttc ctggtagaga ccggcaaccg cccccgcggt
    15241 ccgtcggacg tcgaaggccg cccgggtgtg ccgcagggcc cggcgggaga ccgcctcgcg
    15301 cagatccgga tcggtgagca gggcggtcag cgccgcggcc agggccgccg gatcctccgg
    15361 tggtacgaga cagtggtcct cgtcgccggg cggcaggctc tcccgcgcgc cgttcacatc
    15421 ggtcagcacg acggcgcgtc cgcaggccat cgcctccagc ggggccagcg ccatgccttc
    15481 ccagcgggag ggcagcacga ggacgtccgc cgcgtggatc cacggccgta cgtcctcgca
    15541 ggctccggtg aacagcacac ccggcggggc cgattccgca aggccgtccc ggtcgggccc
    15601 gtcgcccacc aggaccagcc gtgcccccgg cagcgccatc cggcgccagg cccgcagcag
    15661 gatgtcctgg cccttctgcc gggtcaggcg gccgacgcag acgaccagcg gggcatccgg
    15721 gtccgtgccc tgcaggaggg ggagggtggc gcgggcctcc gcccggaccg tgtggtcagc
    15781 ggggcggaac cggtcgaggt cgatgccgtt gtggatgacc gaccagcggg cggcgatgcc
    15841 cgcctcctgc ccggtgcggc gctccgactc gctgacacac aggatgtgat cggcccagcg
    15901 cgcgccgaac cgctcccagc cgagcgcgag ttccgcggtg cgtccgccga cggcctcgaa
    15961 ggaccaggcg tgcggctgga acaccgtggg gacccggccg cgtaccgcga tccggcccgc
    16021 gaggcccgcc ttggcgctgt gggcgtgcac cacgtgcggg cggctcgcgc ggacgatccg
    16081 gcgcgcggcc gcgacctcac cggccagtcg gggcccaggg gaacgggtcg cggaccagcc
    16141 gtggacctcg gcccccgccg ccgccgcccc gacggccagc gggctcccgg gagggcaggc
    16201 caccacggga cgcagtccgg caccggcctg ggccctgacg agatcggtga cgacccgggc
    16261 cactccgccg tccacgggct gaaccacatg aaggaccgtc aattgtcttt ctcgagtacg
    16321 acgcatgtgc agcacgaacg gctctcttcg ctcaatccgg tgagtaaagc cgaggtgcac
    16381 tttggcagat atgtggcgat atcgtgcgcg tgactcgctc atacgaccac atggggattg
    16441 cacgtccggg tgagctgttc gagtggtcgt gcggcagacc ggcgcagacc cgggcgccct
    16501 tcacgggccc gtggcaaaag ggctttcggg gggtctggcg cgggcagcgg ctcaagtgtt
    16561 ccgcgcgacg cgcgccggtt atacggtcag tcttttccgg tggcgcacac accgccgatc
    16621 gccgcaatgg atggcggcac catccaccgt ccggctcccg ccgttcccgg ggtggtgacg
    16681 gcacggtcca cgaaacgccc ggagcgcccc ggacggtgtc cggggcgctc cgggcgacgg
    16741 gtcggcccac gcggtcggtg ggccgccgtg ggtcagccgg tgcggtccac gagatacggg
    16801 atcagcgtga gcagatccct cttggcctcg tcggccagcg gcacccggtc cagacaggca
    16861 cgggccgcgg ccaggtgctc ctgcgcctcg gtgaccgccg cccgccgccc gcccgcctcg
    16921 tcgatcagct ccgccgcccg gcgcgccgcc gcgtcgtcga gcggcccggc ggaggtgagc
    16981 agcgcgtcga gacgcccggc cgccggatgg tcggcggaca gtgccgcgag aaccgggtac
    17041 gtcttcttga accgccgcag atcgctgtgc acgggtttcc ccgtcacctg cgggtcgccc
    17101 cagatcccca acaggtcgtc cacggcctgg aacgccaccc ccacatgccg gcccgccaga
    17161 tccagcgcct cggcggtgga cgccggagcg cccgccagca ccgcgcccag ggcggccgcg
    17221 cagccgagca gggagcccgt cttgtgggtg gccatcgccc ggtactcgtg cggcaggacg
    17281 gccccgggac cggaccacgg ccgggactcg aagagcaggt cctgcgcctg accgtgcacc
    17341 agatcaccca gcgcgcccgc caggtgccgc accgccgcgg ggccgccggg gccgggagcc
    17401 tccgcgaggg tggagacggc cagggcgaac agggcgtccc ccgcgaggac cgccgggccg
    17461 gtgccgtacg ccttccacag cgtcggccgg cggcgtcggg tctcgtcgcc gtccatgatg
    17521 tcgtcgtgga tcagcgagaa ggtgtggatc agctcgaccg ccaccgcccc gagcagcccg
    17581 tcctcaccgc tgccgcccgc cgcctccgcg ccgagcaccg cgagcgcctg gcggaccccc
    17641 ttgccctgcg atccgggcac gggctcgccg tcggcaccgc gccagcccag cgagaaggcc
    17701 gccgcctccg cgtgccaggg gtgcagccgg cccaccgacg ccaccagggc cgggcgcacc
    17761 agctcgcggc accggtccag tatctgcggt gcgctggccc ggcgggtcgt ggagagcgtc
    17821 atcggcggtc gtccccggcc ccggccgacg aaggctccac gccgagttcg gcgtacgcct
    17881 tctcgaccat ctcccgggcg ttcagcagcc cgatccggct gagcctgcct cgcagttcgt
    17941 ccaggtcggc ggcggtggcg tggcggtccc gcccgagcct ggcccgggcc ttgaccaggc
    18001 cgagcgaggc cagcgcctcg ccccgaggct cgtccatcgc gcggaactcg ccgagcgcct
    18061 gctcgtacac cgtgcgcgcc tcctcgtacc gcccggcgcg gaacagcacg ttggcccgca
    18121 tcttgtggtt gtacgccagg gcgctggaga ggttcatctc gcggcaggtg acctcggcct
    18181 cggcgagcag atcgagcgcc cgtccggtcg ccccgtcccg gagggaaacg atgtcggcga
    18241 tgccgcgcag cgcccaggcc cggccccgcc ggtcgtccgc gtcgcccgcc aggaccgccg
    18301 cctcctcgaa catctccagg gccgtgtcca gcgaaccggt gttgcggtgg atctgcgcga
    18361 tgccctccag cgcccagacg gtgtgccggg cctcgccccg ggcgcgggcc tcggccagca
    18421 gttgctcgtg cagtgtcgcg acggtcgcgt agtcgccctg gatccggccg gtctcggcga
    18481 gaccggccag tgagtagccg cgggcgacca cgtcgccgcc ccgcttcccc agctccgcgg
    18541 cgaggctgag cagccggaac gcgaggcgca gcgccccgcg ttgacgcgcc agcgtgccac
    18601 cgctccacag cgcccaggcc atcgccccgg tgttccccgc cgaccgcgcc gcccggtagc
    18661 tggccttcca ggcccggtcg gcctccgcca cctggccgag cctgcggtgc gcctcggcca
    18721 cggccaggcc ggagcgcgcc acctcctcct gcgatccgga gagctcggcc tgcctcaagt
    18781 ggcgtacgcc ctcggccagt acgtcggtga gggaggcgtt caccgacatc ttggtgagag
    18841 ctccctggta ctcgggcgcc agtgccttgg tctgcatggg tgccttccgc gcggtgccgg
    18901 gcccgaaacc ggacaactat acccactatg tatacatggt aggtatagtc ggccggtcgt
    18961 gcaggccggg atcttgtggg ggtggggcgc cgctcgtcat gtgcggcgaa ccgtcctgtc
    19021 gtcgatcaag acggcagggg cgcgcgcggg gttgctcggg ggaccaggtc gttccgggcc
    19081 ggctcacccg tgtcccgtta cgccccgccc tgtaccctct ccgtacgccg cagccggtgg
    19141 cgtaccgcgc gccgggcgac cgggcccagc tcgtccagca ccccggccag cgcggcgagg
    19201 tgctccagtg cctcgaaggc ccgctccgcg cccttcgggt cgacgccctc gtacatctcc
    19261 agacccacga acgccccggt cacggcgcgg gcgagtccca ccggatcggt gaactcgccc
    19321 agcggcgagt ccgccaggat ccggacgagg gccttctcga tctcggcggt ccacaggtcg
    19381 agcccggccg cggtcgcggg cgccagccgg ggctgggtct gggcccccgc gagcacctgc
    19441 gccaggaagg cgacatggcc cccggcccgc tcctcctcgt gcagctcacg cccgcaccgc
    19501 aggagttcgg cgagcgtggt gacggcggcg agccggtcgc ggtggcgggc cacgcgctgc
    19561 tcggcaccgt accggcaggc cgccgcgagc agttcgtcga ccgaaccgaa gtggtagaag
    19621 accagtgcct ggttgacccc ggccgaggcc gccaccgaac gggccgacgt cttcgcgatg
    19681 ccgtgctcgg cgagcgtgcg cagcgcgccc tccaagagct tggtccgggt gtccgtcccg
    19741 gtcgcgcccg ccgtcatgcc cgcgcctcct cgcggaccgg gcgcagaccg gcgcgtacgc
    19801 cgtggcgcag ggcgtcgacg tagcggacgc ggaaggtccc ctcgtacccg aacagcgggc
    19861 cgaagcggcg gttggtcacc gtgacccgga tacggaagcg gcccgtggcg tcgtcgaagg
    19921 actcgcggac ctcggcatct ccgccgatca gatccgggac ccgcaggtcg aggggcccct
    19981 cgcggaagcg gtgctccccg gagcggatca gcagcgaacc gtcgggctcc gcggtcagcc
    20041 gcaggtccgt ggccaggtgc tggtgcgtac cgaggtagtc cagcacgcag gaccgctcgg
    20101 ggctgtgcac catcgtggcg tcgaagcggc gcgcaccgcc cggcagggcg aaggtccgga
    20161 cgaaggtgac ggtctcccgg ccgtgggagt cggtgtacgg cacgttctcg atggtgaacg
    20221 gaacgtcgcg gccggtcctc ggcaccagga tgttgcgcgt ggcaccgagc gcgaggaacg
    20281 gcttgacgaa cgcccggccg tgccagatcc ggtccatgga cccgcgcccc acgcacgcct
    20341 cgccgctctc cagcccgacc gagaagcggc gctgcagccg ggggtggagc cgcgcgaagt
    20401 cgtctcccat cgcacgggcg aatatcgagg tcacgggcgc tccagacggg ccaggaggga
    20461 cggtgcggcg gccggtcggc cgggcggtct gcgcagacac cgccgggcgg cgggtgtgag
    20521 cgacgacggt ggcgccagca gcgcggccag agcggcaggc agcacggccg ccggaccgaa
    20581 ggggagggcc gccgccacga gaaggagccg taccagcacc tccaccaggg cgtgcgccag
    20641 cgaccgggcc gggctgatgt cgcgctcgca ccacagccgc agccggtcga aggaccaggc
    20701 cgtcgcccag cccatcagtg gccggaacac gagccggtcc gcgaccgcgc cgaagcggcc
    20761 ccagcgggtc cggtagtcgt accccgtcag aaaacggatg ccgtcggcgg tggggacgta
    20821 gcgccagtag ccgctgccct cggcgagcag cgacagccgc tccggcgaag cgaaccgcag
    20881 ggcggagacc cgctcgccgt ccgcccgctc ccgctcgccc gcgctggtcc cggtccccgc
    20941 cacggtcagg aagggcagca cccgggtcgc gtaccggaag cgctgggcgg agcctgccgg
    21001 accgggcagc ggtctgatct cggtgaagcg cagatcccaa cgctggtgct gggcgggatc
    21061 ctgcgtccgg gcccacaggc ggtccggatc ggtacggatc aacgcctcta tgtacagccc
    21121 cacgtctggt cccccggtcg ccgcgcgtat ttgagcgagt gctcaaaccc ctccgcgttt
    21181 caggacgcta tcagagggga ttgagcagtc gctcaacccc ctctgggcgg tcggtgctca
    21241 ggccgtggcc ggaggccagg gcacctcggc cagcagcggg aggatgtgct tctcctcgtg
    21301 gtcgaggtgg gcggtcagct cctcggtcat ccgggccagc tcggcgcgga agcggtccgg
    21361 ttccgtgatg gccgcgtcgg ccagcagggc cgcgagcgcc gcctgcacgg ccgcgatgga
    21421 acggtgttcc tcccgcagcc ggtcgaagac gtcccgcaga tgggggtggt ggccctccat
    21481 ggtggggaac atgtgcccgt cctcggccgt gtggtggaac tccagcgcct ggcagaaggc
    21541 caggcagcgc tgccggatct gcagaccgag acccggggcg ggcggttcgc cgacgccccc
    21601 gtaccccgcc cgcgcggcga agtacacctc ggtctcgtcg tgcacgtggc gcagttggcc
    21661 ccgcagccag gtgtgcacct cgaccagctt gtcggcgagc gaggtgaccg ggggagccgc
    21721 cgcgtcgggg tcggggagtt cgagcaccac gaccggcagc acccggtcgg tggcgtcctg
    21781 gtactccgcg tacccgggcg cctcggcgac gacccgggcg aagagttcgt cgcgccgggc
    21841 accttcggcg ggtacggcga gggactcgaa cgcctcgtcc cccagctcga cctgcacggt
    21901 ggggtgggcg aggaggttgc gataccagtc ggggtggagc ggtgcgccga ggttggaggc
    21961 gacgacgagg agccggcggg cgtcgcggac gtagccgagc ggggtggtgt gaggctttcc
    22021 ggaacgggcg ccggtggtgg tgagcagaag gaggtcggtg cccgcgaagg ggccgccgac
    22081 cttcccggcg ttggcacgga attcggtgat gacggactgc tggaaggtct ggggcatgga
    22141 ggttctgggt ctcccggaag aaatgcgggc agtgaaggcc cggtgcgtcg cggagtgtcg
    22201 gccgctgggt gcgcgaaggc agccaggggc ggagatggcc cggggccgga gagggcccgg
    22261 ggccggagat gctcagatgc agggggcgat gaagggactc atggcgtcat ccctgggaac
    22321 aggtgctggc ttgaccgccg gccggcccag atctctttgg ccgacgtcac gctgcacgga
    22381 cagcatgaga acccgatccg ctcgtccctg tcaatgcggg ggcgggcagc gcaagggcgg
    22441 gaatcgtgaa ggagggaatc gcgaaggcgg gcagcgccgg gaaacgcgtt gcccgccctg
    22501 gggaagcctg cgaggcttcc ggccatgccc acgcaacaga agactcctgc gccgctgccc
    22561 ccgactcctc gcacgcaccc ggtggaggcg ctcttctcgc acggccgcct ggtcgcgatc
    22621 ccgcgcaagg aggcccgccg ggagcagctg ctcacccacc tcgccgacac gctgttcgag
    22681 cgggagcgct cgtacaccga gcgcgaggtg aacgaggcgc tgctcaccgt ccacgaggac
    22741 tgctccgcac tgcgccgcta tctcgtcgtc gccgggctgc tggtccggcc ccgggacggc
    22801 agcagctatc gacggggccg ctgaccggca cggacggtca gcgcaacggg cccccgggcc
    22861 tcgtcagttg agggtgtcgg ggtccggtcc ggtgcgcagg ccccggtcca gggcggcgac
    22921 ggcgtccatg tcggcggccg acaactcgaa gtcgaagacg tcgatgttct gtcggatccg
    22981 ctcgggtgtg accgacttcg ggatcacgat gttgccgagc tggagtatcc ggcctccagg
    23041 gcggtggaga cggccgcggt ggtctcctcg tcgggcacct ggaagacgcc gaagccgagc
    23101 tgggggatgg tcacgccgtt gttgagcgtg acggtgggaa cggtgggcgg ccttccgtag
    23161 cgcggtgcgc accgatatgg acggcgcgcg acgtttactg gcgtcggcaa taattgcata
    23221 cgcgggctat gtgtaaacgc gggcaagatt tgggaggggg gttgtccgat ggggggcgtg
    23281 cccccatcgc cgaaccgggg cggtcatgtg ctggactggc gctttcgccc ggatcggcca
    23341 gcaccccgga tacaggagtt cttgtgagca gttaccggca gcccggcgtc gtcctcaccg
    23401 accgccgctt caccgtgccc ctcgaccaca gcgaccccgc cggcgagcag atcgaggtgt
    23461 acggccggga agcggtcgcc gcctcccggg ccggcgagga actgccctgg ctggtctatc
    23521 tggagggcgg tcccggcttc ggcgcgcgcc ggttcgtcgg tacggaggcc tggctcggcc
    23581 gggccctgcg cgagttccgg gtgctgctcc tggaccagcg ggggaccggt ctctccaccc
    23641 ccgccaaccg gcagaccctg ccgctgcgcg gcggcccgcg cgagcaggcc ggctacctcg
    23701 cccacttccg cgccgactcc atcgtccgcg actgcgagct gatccggcag cggctcaccg
    23761 gcggagcacc ctggacggtc ctcggccagt ccttcggcgg cttctgcgcc gtccgctacc
    23821 tctcagccgc cccggaaggg ctgaaggagg tcctgatcac cggcgggctg ccctcgctgg
    23881 acgcgcacgc ggacgacgtc taccgggccg cgtacccccg catcgagcgg aaggtcgccg
    23941 cccactacgc ccgctacccg caggacgtcg agcgcgcccg cgccatcgcc gcccacctcg
    24001 cccagcatcg gcccgagtac gccggacacc ggctcacccc cgagggcttc cagtcgctcg
    24061 gcatcatgct cggctccggc agtggcggcc accagctgca ctacctgctg gagaacgcgt
    24121 tcgtccgcac tccgcacggc accgaactct ccgacacctt ccaggaagcg atgcgcaccg
    24181 ccgtctcctt cgccggacac ccgctctacg ccctgctgca cgaggccatc tacgggcagg
    24241 gcgaacgcgc cacggactgg gccgccgagc gcgtacgggg agagttcccg cagttcgacg
    24301 cggcgaccgc gctgaagggc gacgggccgc tcctcttcac cggcgagacc atccacccct
    24361 ggcacttcga cgtcgacccg gcgctgcggc ccctgcgcga gaccgccgag ctgctggccc
    24421 ggcggaccga ctggccggtg ctgtacgacc ccgaacggct cgccgccaac gaggtcccgg
    24481 tcgcggcggc cgtctaccac gacgacatgt acgtcgacac cgcggactcg ctgcgcacgg
    24541 cggcggcgat ccgagggctg cggacctggg tgacgaacga gtacgagcac gacggggtcc
    24601 gcgcgggtgg cccccgggtc ctggaccggc tgctgtccct ggtgcgcgac gaggcctgac
    24661 ccggccgggt cagcgctgga gctcctccag cgtggcgtcc aggtcgccgg cggcccgtgg
    24721 ggcccggttg tgcggcagct tggagaggac cgccgccatt ccgcaggtgt tgctgagcgc
    24781 cgaatagacc aggcccgtgc cgacgcccgc ggagagccag cgcgccgccg ggaagcgaat
    24841 ccccgccacc aggcccgcca ccaccagcga acccgccgcg agccgcacct gacgctccat
    24901 ggcccacgtg gtgcgcgcac cctcggggcg gtccaggccg cggccgtcgc cctcccaggc
    24961 ggacgtgccg ccggtcagcg tcacggcctc gatgtccgcg cccgcgagga tctcgcacgc
    25021 ccgggtggac cggacccccg aggcgcacac caccagcagc gaaccgcgcg cggaggcgga
    25081 cttgagcgcg ggcagggcgt ccggcagttt gtcgagcggg atgttgaggg cgccggggac
    25141 atgcccggcg gcgtactcgc ccggagcccg cacgtcgatc acggtgaact cctccaggcg
    25201 ggctgcggcc tgggcggggg agagggaggc gggggtgggc acgaggggct tcctttcgtt
    25261 cggccggact ccagcgtcgc acgtccgccg ccggagccgg gggtagcctg cccgtatgac
    25321 gccgcagcga ctcgaaccca tgcccggcga ctggcagcgc gccctggccg tggtcgccca
    25381 cccggacgac ctggagtacg gcgcggccgc cgccgttgcc gagtggaccg acggcgggcg
    25441 tgaggtcgtc tacctcctcg ccagccgcgg cgaggccggg atcgacaccc tgccgcccga
    25501 ggagtgcgca ccggtgcgcg aacgggagca gcgggcgagc gccgccgtcg tcggcgtacg
    25561 gaccgtggag ttcctggacc accgcgacgg cgtcatcgaa tacggcaccg ggctgcgccg
    25621 cgacatcgcc gcggccatcc gccgtcaccg ccccgaactg gtcgtcacgc tcaatcaccg
    25681 ggacacctgg ggcgggccgc ctggaacacc cccgaccacc gcgcggtcgg gcgcgccacc
    25741 ctcgacgccg tcgccgacgc aggcaaccgc tggatcttcc ccgacctgga cgagcaggga
    25801 ctccagccgt ggaagggggt gcgctggatc gccgtggcgg gcagcgaccg gcccacccac
    25861 gcggtcgacg cgacggccgg cctcgaacgc tcggtccgct cgctgctgga acaccgtacg
    25921 tacatcgagg cgctgacccg acaggacccg gaacggtact gccggacctt tctgacgggc
    25981 atggtcgagg ccgccgccga gcggttcggc ggccggcccg cggtcacctt cgaggtcttc
    26041 gcgcagtagg gcacgtcgtc gtgtgaggtg cccggtcggc gagattgtcc ggttgacaaa
    26101 acggcttgcc gattctgcaa tggccggatg aaggaacgcg accgggacga cccggaactg
    26161 gagtccgtcc tctccggcgt cggcccccga ctgcgccgac tgcgcaagga ccgcggggtc
    26221 accctcgccg ccctctcggc cgccaccggc atctccgttt ccacgctctc ccggctggaa
    26281 tccggcggtc gtcgccccag cctcgaactg atgctgccga tcgcccgcgc ccacgaggtg
    26341 ccgctcgacg acctcgtggg cgccgcaccc gtcggcgacc cccgggtgcg ggccaagccg
    26401 atcgtgcagc acggccggac catgctgccg ctgaccgccc ggccgggcgg cctccaggcg
    26461 tacaagctga tccaggagcc cggcagtggc ggcccgccgg agcagcgcac gcacgaggga
    26521 tacgagtggc tgttcgtgct ctccggcaaa ctgcggctgc tgctggccga acacgatctg
    26581 gtgctggagc cgggcgaggc cgcggagttc gacacccggc tgccgcactg gttcggtccc
    26641 gccggggacg agacggtgga gttcctcagc cttttcggtc cgcagggcga gcggatgcac
    26701 gtacgggcga agccccggcg cggctgaggt ccgaagcctt ccgaggtccg ggccgggggt
    26761 gttcccagat cgacaagcga ccgcttagta tgcggcgcag cagtggtaat gccgaccgct
    26821 tcggcggttg acgccgacag tgttgtggag gcccctcatg caggcatggc gagtgcaccg
    26881 gaacggcgag ccgggcgagg tgatgcggct ggaggagacg gaccggccca cgcccggcga
    26941 cgggcaggtg ctcgtcgagg tccgcgcggc gaacgtcaac ttccccgacg ccctgctctg
    27001 ccggggccag taccaggtgc ggccgccgct gcccttcact ccgggcctgg aggtgtgcgg
    27061 caccaccgag gacggacggc gggtcctcgc caaccccgtt ctgccccacg gcggcttcgc
    27121 cgactggatc gtcgcgcacg aggcggccct gctgcccgcc cccgacgccc tggacgacgc
    27181 cgaggcggcc gcactgcacg tcggctacca gacgggctgg ttcggcctgc accgccgagc
    27241 ccacctccag cccggcgaga ccctcctcgt ccacgcggcg gccggcggtg tcggcagcgc
    27301 cgccgtccag ctcgggaagg ccgcgggcgc gaaggtcatc ggcgtcgtcg gcggccccga
    27361 caaggctgcc gtcgcccgcg agctcggctg tgacctggtc atcgaccggc ggagcgagga
    27421 catcgtcgcc gccgtcaagg aagccaccgg cgggcgcggc gcggacgtcg tctacgaccc
    27481 ggtcggcggc gacgcgtaca ccaagtccac caagtgcgtc gccttcgagg ggcgcatcct
    27541 cctcatcggc ttcgccagcg gagtcatccc caccccggcc ctcaaccacg ccctggtgaa
    27601 gaactactcg gtcgtcggac tgcactgggg cctctacaac accaaggacc cggccgccgt
    27661 ccgcgcctgc cacgaggagc tgaccaagct cgccgagcag ggcatcgtga agccgctgat
    27721 cagcgagcgt gtcgcgatgg ccgatgcggc cgacgccgtc cagcgcgtcg ccgacggcac
    27781 cagcaccggc cgcatcgtcg tccttcccgg agacgcccga tg
//
