LOCUS       NZ_CP021707            21053 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. S063 chromosome, complete genome.
ACCESSION   NZ_CP021707
VERSION     NZ_CP021707.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S063
  ORGANISM  Streptomyces sp. S063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Complete genome sequence of Streptomyces sp. S063, a producer of
            anti-complement compounds and various secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAY-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:19:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,905
            CDSs (total)                      :: 6,817
            Genes (coding)                    :: 6,244
            CDSs (with protein)               :: 6,244
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 574
            CDSs (without protein)            :: 573
            Pseudo Genes (ambiguous residues) :: 0 of 574
            Pseudo Genes (frameshifted)       :: 432 of 574
            Pseudo Genes (incomplete)         :: 192 of 574
            Pseudo Genes (internal stop)      :: 13 of 574
            Pseudo Genes (multiple problems)  :: 61 of 574
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 327485
            Orig. end                         :: 348538
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021707.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Xinqing Zhao, Life Science
            and Biotechnology, Shanghai Jiaotong University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(330..1431)
                     /locus_tag="CCZ36_RS01555"
                     /pseudo=""
     CDS             complement(330..1431)
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455231.1"
                     /locus_tag="CCZ36_RS01555"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRQRRAKWIPLGVIVLGVVLDLVTPADVTSAPLLMAAPVAAAPL
                     LGLRGIIAIGALAMAVHAVLAWYDGTFGWQRGVANQLTLVAVTVLAVLIDRSLEGRDAR
                     TRRARHIAAVAQSAVLPRPPSRLGELRIAARYVPAEDEAMIGGDLYVVQDTPHGVRVMV
                     GDVRGKGLGAVSAVCADLGAFRYAADEAEDLPGLVAALERALLREGGRRGGQDQDEGFT
                     TALIAEFADDLGTVRVVNRGHPPPVLLDARAGPPSSNPPRRRPRSA"
     gene            complement(1359..2324)
                     /locus_tag="CCZ36_RS01560"
     CDS             complement(1359..2324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044323.1"
                     /locus_tag="CCZ36_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_237302570.1"
                     /transl_table=11
                     /translation="MRARSGPTVEHRVLAVRLRMLRERAGVSLRAAAEALDAHPATVRR
                     IERAETGLDARQVGELLRCYGVPPAVAEPIMAGLAAANLPGWWHRWRDTMEAWQQEVIG
                     VESSASLVRTWHPALVPELLRTPAYAAALHRTQYPEDSPARRERRVELLRERRRRLCER
                     GATLWALFPAAALHTRVGDRATMEGQRAALAEAMKEQHVTVQVVPLDHPPHPLTGVPPL
                     HILRVPAPEIGDQAVLETPGVRVDLIDDPEAVTAHRIRLDAACAAAPGPGPRCRSDRVR
                     PKPAGMRRAPVPCSVGEWCGSAGPSGSRWGSSCWASCWTW"
     misc_feature    2285..2299
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.64"
                     /tool="antismash"
     misc_feature    complement(2487..2501)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            2511..2921
                     /locus_tag="CCZ36_RS01565"
     CDS             2511..2921
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455227.1"
                     /locus_tag="CCZ36_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_256094558.1"
                     /transl_table=11
                     /translation="MPGGVPEARHRVQEAMRAWGEPAERIEAAALIATELVTNAVQHTS
                     TRRIRCRLLRSAGGVRICVWNRGRARIPAPASPADSAGLPVGQVPAAADLEGDPALARL
                     PEDGRGLLLVDALAARWGTRAALAGRLVWADL"
     gene            complement(2949..3661)
                     /locus_tag="CCZ36_RS01570"
                     /pseudo=""
     CDS             complement(2949..3661)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382055.1"
                     /locus_tag="CCZ36_RS01570"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ribonuclease H"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNESIIAACDGASKGNPGPAAWAWVVADAQGEPVRWEAGPLGAAT
                     NNVAELTALAQLLESTDPAVPVEVRMDSQYAMNAVTKWLPGWKRNGWKTSGGKPVANRE
                     LVTRIDALLADRSVTFRYVPAHQVNGDPLNAIADQAASEVAVTQLPAGTAHGATALPVP
                     APARSTKGRTEASGASGGSKGRGPGARPGAGGPAARSRRASRAGATAASRTRPRSRSRR
                     TRTAGATRSAVRSPP"
     gene            3875..5770
                     /locus_tag="CCZ36_RS01575"
                     /pseudo=""
     CDS             3875..5770
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061756.1"
                     /locus_tag="CCZ36_RS01575"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDMEVTAWHSLHSAMNAQQDRRPFSRASLRRIMLFARPTDGGSTA
                     SCC"
     misc_feature    complement(3876..3890)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.77"
                     /tool="antismash"
     gene            complement(5838..6104)
                     /locus_tag="CCZ36_RS01580"
     CDS             complement(5838..6104)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069846.1"
                     /locus_tag="CCZ36_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128816898.1"
                     /transl_table=11
                     /translation="MTTEAPRRPRIEHVTTAGSALAVTLLPLVVGVLLAKTLAADPMTS
                     VNALVTNGHRPRVSPKEWRRCGGHALRRLRTAERPSFGRSGAR"
     gene            6257..6909
                     /locus_tag="CCZ36_RS01585"
                     /pseudo=""
     CDS             6257..6909
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069847.1"
                     /locus_tag="CCZ36_RS01585"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGDSQGRAGEGHGSEAAAVFDALGAEYERAFAASAAHRQSLERLL
                     AGLTPAAACWMWAAGRAGRRHRPWRTRATGCWASTCRR"
     misc_feature    complement(7135..7150)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(7163..7183)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.75"
                     /tool="antismash"
     gene            7227..7823
                     /locus_tag="CCZ36_RS01590"
     CDS             7227..7823
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069848.1"
                     /locus_tag="CCZ36_RS01590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbonic anhydrase"
                     /protein_id="WP_069735222.1"
                     /transl_table=11
                     /translation="MQSLVEHARTFTEHVAANAKDFERFADGQTPEALFVTCSDSRVVP
                     SLITGARPGQLFELRTAGNIVPPYPGRDRPTGEAATIEYALCVLQVRDIIVCGHSHCGA
                     VGAILRGDDLSAMPAVRHWLERSTDGRTPPDDAGDLPGAVQAHALAQLDTLRGYPAVRE
                     RLAEGSLGLHAWYYEVHTGSVSVHRPERGTEFARL"
     gene            7896..9362
                     /locus_tag="CCZ36_RS01595"
                     /pseudo=""
     CDS             7896..9362
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015116 - sulfate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970902.1"
                     /locus_tag="CCZ36_RS01595"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SulP family inorganic anion transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MISAKELKNPTSYDVTCWRHSSSSWSRCRCASASPSPPESRPNWA
                     WSPASSADSSSASSPEANSRSAALPPDSPSSSSKPSRSSA"
     gene            9731..10008
                     /locus_tag="CCZ36_RS01605"
                     /pseudo=""
     CDS             9731..10008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381775.1"
                     /locus_tag="CCZ36_RS01605"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTSESGHGETLDERAVLLVAGAADLAVSAIGSALGAVRGLLRRSD
                     TAELAAEAEHELKARGGWCWTGTRPRPLPIWRSWPARPSHGGPPKMS"
     gene            10001..11053
                     /locus_tag="CCZ36_RS01610"
     CDS             10001..11053
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059134.1"
                     /locus_tag="CCZ36_RS01610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_128816899.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.7e-35, bitscore:
                     121.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRWDAAAFKTRVDEVLHQFVAREVDLFAKIDPSLAPVAAQLEA
                     AVQDGKRLRAAFCYWGWRAVGQPDSSALLRAAASLELIHAAAVVHDDLIDDSALRHGRP
                     TAHVALRGAVRRRPRSAAAARSLAMLVGDLLMGMAGQLFATSGLPAAYVGRARPLWSVL
                     GRELIAGECLEILRTGSEPDTDASLQVIRYKTAKYTVEQPLLIGGALAGAGGRLREGYS
                     AYGLPLGEAFQLRDDLLGLFGDPEHTGKANADDVRGQRPTALLAETWRIAGEDDRTRLR
                     ALLGQRGLDEAGLQAVREVMCRLRAPSLVEDMITARVEEALGALGDLDLPAGPADALGA
                     LANSATVRLF"
     gene            11097..12389
                     /locus_tag="CCZ36_RS01615"
     CDS             11097..12389
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978298.1"
                     /locus_tag="CCZ36_RS01615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_128816900.1"
                     /transl_table=11
                     /translation="MNYTEASMNVLRQGGDELADATVAALFERGEVGKFNTLMRHVSTT
                     GTPLPDGLPDVAREYLRTTSAPPDWVDWELMEKARLFFIDNNVHISTALSFASMPACYV
                     VPHVARLLSATHGLRYPSKRMAETGQFTVYLMQPDAFEAGGRFIPAAQKVRLLHASIRH
                     HLQRENRWDTSGLGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSTEGAEAYYYAWRVV
                     GAMLGVDQQAVPPTLDDARAFLDLYMVRHMGPSEEGTLLTRQLIDLYEEVVPGTLFDPV
                     VSALIRHLIGDTCADWLRVPRSSWDTAVKAVPHLLGLLETIEDRSPLGARALDHLGRLT
                     TLLELSSLTRGRVMHYAIPEQLKDAYGVTPASHRARRWNPPPPPPQADPRADPLPPAAQ
                     GPEPPSPRRPSHRAPRQFPWSRPLDDWSRPS"
     gene            12609..14363
                     /locus_tag="CCZ36_RS01620"
                     /pseudo=""
     CDS             12609..14363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010062579.1"
                     /locus_tag="CCZ36_RS01620"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 18 chitinase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVGLATPAQAAASATATYTKASDWGSGFEGKWTVKNTGTTTLSAW
                     TVEWDFPANTKVTSAWDATVTNSANHWTAKNLGWNGTLAPARPSPSASTDPAPAHPPAA
                     SSTATRATAAPPTPATTPLRSGQAHRERHHQLLGEAVLGGRHGRQGHQELRRQARRCHG
                     RNRHRHHVHQHRTDRGHGLQLLRGGPRHRRPDRTGLGRHDGPYHRWRRRR"
     gene            complement(14527..14964)
                     /locus_tag="CCZ36_RS01625"
     CDS             complement(14527..14964)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956703.1"
                     /locus_tag="CCZ36_RS01625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2267 domain-containing protein"
                     /protein_id="WP_069735228.1"
                     /transl_table=11
                     /translation="MTHEPRNAGAPMDTTFGLLLEKIRYEGAYPTRERAEESLCAVLGA
                     LGRQITGDERVALAAALPEEAARVFTAEVPAVKQLAGAAFVAELAERTGGTPATARWDA
                     GVVLSQIAALVGDDLVAEVVSCLPPGYALLFGRAELLAQAA"
     gene            complement(15069..15465)
                     /locus_tag="CCZ36_RS01630"
                     /pseudo=""
     CDS             complement(15069..15465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069852.1"
                     /locus_tag="CCZ36_RS01630"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="DUF2267 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTLRWEAFLDRVQERGEYETHGEAERAARVVLALLGAHLVGGERA
                     ELAARLPETMALILLNPLQAAEPLSPERFVRATAAWIEGAGEQTARWDVGAVLSRRRGG
                     GRGSHPTHPASTAARV"
     misc_feature    complement(15427..15440)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            complement(15564..15995)
                     /locus_tag="CCZ36_RS01635"
     CDS             complement(15564..15995)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069853.1"
                     /locus_tag="CCZ36_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_069735230.1"
                     /transl_table=11
                     /translation="MLMRTDPFRELDRITEQLLRPGTWSRPSAMPMDAYREGDEYVVAF
                     DLPGVSPDAIDIDVERNMLTVKAERRPAVNADNVQMELSERPLGVFSRQIVLADTLDTE
                     RIDADYEAGVLTLRIPIAERAKPRKIAIGGESRRKQIKG"
     misc_feature    complement(15983..16003)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.99"
                     /tool="antismash"
     gene            16135..16818
                     /locus_tag="CCZ36_RS01640"
     CDS             16135..16818
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069854.1"
                     /locus_tag="CCZ36_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HSP18 transcriptional regulator"
                     /protein_id="WP_128816901.1"
                     /transl_table=11
                     /translation="MTPPTQPEPPRRSTPDAVSFLAAWAALQTIDEAVRDALGHAGDAT
                     SGPPPATERAEALASLQLLREVREQLAGWETGLIETARAAGASWADLADPLGVASRQAA
                     ERRYLRLRPGSEGSTGEQRVRATRDRRAGDRSITAWARQHAADLRSLAGRIAALTDLPA
                     AADAPLDRLRQALGTDDAAALVTPLTALHPHLAPGHGELADRVDALTQHTGRLREDTAA
                     RRRGD"
     gene            complement(16912..17696)
                     /locus_tag="CCZ36_RS01645"
                     /pseudo=""
     CDS             complement(16912..17696)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606939.1"
                     /locus_tag="CCZ36_RS01645"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSADDDEFRRSIRSDVPHSARVWNAWLGGKDHYPVDRSWPRR"
     gene            complement(17824..17979)
                     /locus_tag="CCZ36_RS34655"
     CDS             complement(17824..17979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061771.1"
                     /locus_tag="CCZ36_RS34655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_164873471.1"
                     /transl_table=11
                     /translation="MDLFDGELGGRDDRGLDTGGGWSWCGVITVGIFILLAVLISWIFG
                     LVGRLF"
     gene            18165..18419
                     /locus_tag="CCZ36_RS01650"
     CDS             18165..18419
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CCZ36_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_128816902.1"
                     /transl_table=11
                     /translation="MHNGNHVRAEAPWNCSTLPPYGGAKTKVNLYRDGVLVKSAEFRPN
                     GLLNARYGRPGRLRRCGRIRVRDDVRRRRMRLRSHTGAT"
     gene            18460..19919
                     /locus_tag="CCZ36_RS01655"
                     /pseudo=""
     CDS             18460..19919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010069857.1"
                     /locus_tag="CCZ36_RS01655"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTEPTAGLPLSAPEALTVLGALVLVLARWLPDRLRGPAALAAGAL
                     LAGSVTVLVATGTRWQLVPVLVVAAAAGGFALAPLLARRSGRTPWRARWWLAVPGSVVC
                     AALVATGPVSAWAFPVPDFPAPSGRFPVGTETVEWSVPATRSEREKRPRAAGPRPLVVQ
                     LWYPAGRSAPEARRAPYLGRTEAEARTVSAALADYAGVPGFLLDGLPRARSHAVPGAPV
                     ANGGGRFPVVLFSPGLGGARTQNTAWAEELASHGYVVAAVDHPYDSAAVVLSDGRTLRT
                     RVAATGDRAKDRALAEKWTRTRAADLRAMLTRLERLERGGAEGRLAGRLDVGRVAAAGH
                     SIGGAAALRAARQDPRFDAVVDLDGFPHGPVGGRFEQPVLALTQEIGRGTDPDYLPRLT
                     RVLERSDATSYRLTVPGPHTSPSPTPRSICRRSRGSWAPWAVRRGIGSPPGRPCPSSTP
                     PCAAPPSTCPPRSRPTGR"
     misc_feature    21011..21025
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.54"
                     /tool="antismash"
ORIGIN
        1 gccgccccag atgccggagt cctggccgtt ctccagggcc cactccaggc aggcggcctg
       61 gacggggcag gtccggcaga cggccttcgc ctcctcggtc tggacgaccg cggggcccgt
      121 gctcccgatg gggaagaaca ggtccgggtc ctcctcgcgg caggcggcgt gcaagcgcca
      181 gttctcggtg ctgctcaact ctgctcactc ccgaatgtcg tgacgtcgtc ggtgtgttgc
      241 cgtacgtgtc ttccgtgcgg gtgaccgacg atcgacgcct caaacacgta tcgggcgggc
      301 aggtcccgga gccggaagcg cagggcccgc tacgcgtgcg gaggggcagg cgggcggtgc
      361 agcgcgagga gggcctgatc gtcctggatc cggcccccgg tgtgatggcc gacgtcctcg
      421 atcagcagat ggaggatctg cgccggggag gccgggtagc cgaccagcgc gcggtggtgg
      481 acgaggaagg gcagccggac ggacgcgtcg tagaagaccc cggactcgtc gcgcgcctcg
      541 gtggccccgt ccgtgtagca gatgagggtg gcgccgggcg gaaacgggaa cgtgtcgacc
      601 gggcacgacc aggtcccagg ccgctcatgc cgagcggggg cgcctcctcg gagggttcga
      661 ggacggtggc ccggcccggg cgtccaggag caccggcggg ggatgcccgc ggttgacgac
      721 ccgtacggtg ccgaggtcgt cggcgaactc ggcgatcagc gcggtggtga acccctcgtc
      781 ctgatcctgg ccgccgcgcc tgccgccctc gcgcagcagg gcccgctcca gcgcggcgac
      841 caggccgggc aggtcctccg cctcgtccgc cgcgtaccgg aaggccccca ggtccgcgca
      901 gaccgcgctg accgcgccca ggcccttgcc gcgcacgtcc ccgaccatca cgcgcacacc
      961 gtgcggggtg tcctggacga cgtagaggtc gccgccgatc atggcctcgt cctcggcggg
     1021 cacgtaccgg gcggcgatcc ggagctcccc gaggcgcgaa gggggccggg gcaggacggc
     1081 gctctgggcc acggcggcga tatggcgggc gcgccgggtc cgggcgtccc ggccctccag
     1141 ggaacggtcg atgaggacgg ccagcacggt tacggccaca agggtgagct ggttggcgac
     1201 gccgcgctgc cagccgaagg tgccgtcgta ccacgcgagg accgcgtgga cggccatggc
     1261 gagcgccccg atcgcgatga tgccgcgcag gccgagcagc ggcgcggcgg cgaccggggc
     1321 cgccatcagc aggggcgccg aggtgacatc cgccggggtc accaggtcca gcacgacgcc
     1381 cagcacgatg acccccagcg ggatccactt ggccctgcgc tgccgcacca ctcccccacg
     1441 ctgcacggga ctggagcccg ccgcatcccg gcgggcttcg gccggacacg gtcactccgg
     1501 cagcggggcc cggggccggg cgcggcggcg cacgcggcgt cgagccggat gcggtgggcc
     1561 gtcacggcct cggggtcgtc gatgaggtcg acccgcacgc ccggggtctc cagcaccgcc
     1621 tggtccccga tctcgggtgc gggcacccgg aggatgtgca ggggcggtac gccggtcaga
     1681 gggtgcggcg ggtggtcgag gggcaccacc tggacggtga cgtgctgctc cttcatcgcc
     1741 tcggccagcg cggcccgctg cccctccatg gtcgcccggt cgccgacccg cgtatgaagg
     1801 gccgcggccg ggaacagggc ccacagggtg gccccgcgct cgcacagccg acggcggcgt
     1861 tcgcgcagca gctcgacccg gcgttcccgc cgggcggggc tgtcttcggg gtactgcgtg
     1921 cggtggaggg cggcggcgta cgcgggggtg cgcagcagtt cgggcacgag cgccgggtgc
     1981 caggtccgca cgaggctcgc cgaggactcc acgccgatga cctcctgctg ccaggcctcc
     2041 atcgtgtccc gccagcggtg ccaccagccg ggcaggttcg cggccgcgag cccggccatg
     2101 atgggttcgg ccacggcggg cggcacgccg tagcagcgca gcagttcgcc gacctgccgg
     2161 gcgtcgagtc cggtctccgc gcgttcgatg cgccgtacgg tggcggggtg ggcgtccagt
     2221 gcctcggcgg cggcccgcag gctgacgccc gcgcgttccc gcagcatgcg gaggcggacc
     2281 gcgaggacgc ggtgttccac ggtggggccg gaccgggctc tcatgcgcat accttcttcg
     2341 tccagccccg tggcggagca tgacacactc tgtcgcttgc aaagtatgcg ttttgcgtcg
     2401 agagtgcata catgtcggaa atagtcagtt gcgcggagtg tgcccccgat gacggaggtg
     2461 tccaaggtgc cgaaggcacc cgaagtgcac acagctggtg ggtcccccga ttgccaggtg
     2521 gcgtgccgga ggcccggcac cgggtccagg aggccatgcg ggcctggggc gaaccggccg
     2581 agcggatcga ggcggcggct ctgatagcga ccgaactggt caccaacgcg gtgcagcaca
     2641 ccagcacccg gcggatccgc tgccggctcc tgcgctccgc ggggggcgtg cgcatctgcg
     2701 tgtggaaccg cggccgggcc cggatcccgg ccccggcctc tccggccgac tcggcaggcc
     2761 ttcccgtcgg ccaggtcccg gcggcggccg acctcgaagg cgacccggcg ctcgcccgcc
     2821 tgcccgagga cggcaggggc ctcctgctcg tcgacgcgct ggcagcccgc tggggcacgc
     2881 gcgccgcgct ggcggggcgg ctcgtctggg ccgacctctg agactccctt ccccgcctcc
     2941 ccgtccggtc aggcggggac cgtacggcac tccgggtggc cccagccgtt cgggttcttc
     3001 gcgatcggct cctgggccgc gtacggcttg ccgcagtggc accggcccgc gaagcgcgcc
     3061 ttgatcgtgc cgccggaccg cccgctccgg gacgcgcccc cggccccctg cccttcgagc
     3121 cgcccgacgc cccggacgcc tccgtacgcc ccttcgtgga gcgcgcgggc gcgggcaccg
     3181 gcagagccgt cgcgccgtgc gccgtaccgg ccggaagctg ggtgacggcc acctcactgg
     3241 ccgcctggtc ggcgatcgcg ttgagcgggt cgccgttcac ctggtgggcc gggacatagc
     3301 ggaacgtcac cgagcggtcg gcgagcaggg cgtcgatgcg ggtgaccagc tcgcggttgg
     3361 cgacgggctt gcccccggag gtcttccagc cgttgcgctt ccagcccggc agccacttgg
     3421 tcacggcgtt catggcgtac tgcgagtcca tccgcacctc gacgggcacc gccggatcgg
     3481 tggactccag cagctgcgcc agagccgtca gctcggccac gttgttggtc gcggcgccga
     3541 gcggaccggc ctcccagcgc acgggctcgc cctgcgcgtc ggccacgacc cacgcccagg
     3601 cggccggccc ggggttaccc ttcgacgccc cgtcacacgc ggcgatgatg ctctcgttca
     3661 tccctcgatc atgccagccc cgcatgaccg ctccgaccgg ccgcgcgacc ggccggccac
     3721 gaccccgcca ggctctcccc ctgccccggc acaccgtccg tcttgacctc aagcaaactt
     3781 caggttctag cgttctcagt gaacccgggg ccgcacggcc gacggggtcc gcaggccgtc
     3841 gggcgatccg gggccatcga tatcggagcg ccccatggac atggaagtca cggcgtggca
     3901 ttcgctgcac agcgcgatga acgcccagca ggaccgccgg cccttctccc gggcgtcctt
     3961 gcgccgcatc atgctcttcg cccgccccac cgacggcgga tccaccgctt cctgctgctg
     4021 agcgtcctca ccgcgctgct cgcggtggcg actccgctgc tggccgggaa ggtcgtcgac
     4081 acgatcgtca gcggcgagga caccggcgcg gtcacccggc tcgccctgct catcgcgctc
     4141 atcgccgtcg tcgaggccgg cctcggtctg ctcacccgct ggctgtcggc gacgctgggc
     4201 gaggggctga tcctggacct gcgcaccgcc gtcttcgacc atgtgcagaa gatgccggtg
     4261 gccttcttca cccggacccg gaccggcgcc ctggtcagca ggctcaacaa cgacgtgatc
     4321 ggcgcgcagc gggcgttcag caacaccctc tccggagtcg tctccaacct cgtcacgctg
     4381 ctgctgacac tcgcggtgat gctcacgatc tcctggcaga tcaccttgct gtcgctggtg
     4441 ctgcttccgg tgttcgtcgt accggcccgc cggatgggag ccggatggcg ggactccagc
     4501 gggaggcggc cgaccacaac gccgcgatgg gcacccagat gaccgagcgc ttctccgccc
     4561 ccggcgcgac gctcgtcaag ctcttcggcc gcccctcgga cgaatcggcc gagttcgccg
     4621 cccgcgccga ccgggtgcgt gacatcggcg tccgtacggc gatggcccag tcggcgttca
     4681 tcaccgccct caccctggtc tccgccctgg cgctggccct ggtctacggg ctcggcggct
     4741 tctacgccct gcgcggcagc ctggacccgg gcgccgtggt ggcgctggcg ctgctgctga
     4801 cccggctgta cgcgccgctc accgccctcg ccggggcccg ggtcgaggtg atgagcgcgc
     4861 tcgtcagctt cgagcgggtc ttcgaaattc tggacctgaa gccgctgatc gagcagaagc
     4921 cggacgcccg ccgggtgccc gaagggccgg tctccgtgga gttcgacgag gtgtccttcg
     4981 gctaccccac cgccgagaag gtctccctgg cctcgctgga ggaggtcgcc acgctcgacg
     5041 accggggcgg caccccggtc ctgcaccagg tgtccttccg ggccgaaccg ggccagacga
     5101 tcgccctggt gggctcctcg ggcgcgggca agtcgacgat cgcgcagttg ctgccccggc
     5161 tgtacgacgc ggacgccggt tccgtacggc tgaacggtgt cgacgtccgc gatctgagcg
     5221 ccgactcgat ccgggacacg ctcggcatgg tcacccagga cgggcacctg ttccacgagt
     5281 cggtacgcgc caacctgctg atcgcccggc ccgacgcctc cgaggacgag atctgggacg
     5341 ccctgcgccg ctccggctgg acggtctgat cgcctcgctg cccgacgggc tcgacaccgt
     5401 ggtcggcgag cgtggctacc ggctctccgg cggggagcgc cagcgcctca ccatcgcccg
     5461 gctgctgctg gcccgtcagc gggtcgtgat cctcgacgag gcgaccgcgc acctcgactc
     5521 cacctcggag gcggccgtcc aggaggcgct ggccgaggcg ctgtcgggcc ggaccgccct
     5581 ggtgatcgcc caccggctct cgaccgtacg ggcggccgac cggatcctgg tgctggaggc
     5641 gggccgggtc gtcgagagcg gcacgcacgc ggagctgctg gcggccggcg gccggtacga
     5701 ggagctgtac cgcacccagt tcgagcggcc gtcatcggac ggggagcggc cggtccagcc
     5761 ggtcggctga cccgggttcc acgcccgtag cggcgcgcgc tgacgccgtc cggccggacc
     5821 ccaccgggcg ggcggcgtca gcgcgcgccg ctacggccga aggaggggcg ctcggcggtt
     5881 cgcagccgtc gcagggcgtg gccgccgcac cggcgccact ccttcggcga gacccgcggg
     5941 cggtgcccgt tggtgacgag cgcgttcacc gatgtcatcg ggtccgccgc caaggtcttg
     6001 gccaacagca cgccgaccac cagcgggagc agcgtgacgg ccagggcgga accggcggtg
     6061 gtgacgtgct cgatacgggg gcggcgcggc gcttcggtgg tcatacggcc atcgaacagc
     6121 ggccgggtgg cccggacaat cggagaacgt actcaggagc gcggggccgg catactcagg
     6181 cgctcgccgg gggacgctct cagcggccgg gcacacggcc cccggccggc cgccggacca
     6241 cggaaggacc gcctcgatgg gtgacagcca gggacgcgcg ggcgagggtc acggaagtga
     6301 ggccgcggcg gtgttcgacg cgctcggcgc ggagtacgaa cgggccttcg ccgcttcggc
     6361 cgcccaccgg cagtcgctgg agcggctgct ggccggcctg accccggcag cagcgtgctg
     6421 gatgtgggca gcgggacggg ccggccgacg gcacagaccc tggcggacgc gggccaccgg
     6481 gtgctgggcg tcgacgtgtc gccggtgatg accgctctgg cggcccggca ggtaccgggg
     6541 gccgagttcc ggtgcgcgga catccgtgac ctccctctgg cggagggaga gttcgacgcg
     6601 gtctgtgtgt acttctcgct gctccagctg gagcgcggcg agcagagcga cctgttggag
     6661 cggctcgtgc gctccctgcg gcccggcggg ctgctggccg ccgcgacggt accggtggac
     6721 gtcgcgggag tcgacgcggt gttcatgggg cagccggtcc gggtgtccag cttcggcgcc
     6781 gaggagttca ccgccctgac cgcgcgggcg ggggtcgccg tggagtggac gcacagcgcg
     6841 ctgttcaccc cggaccaccc ggcgggcgaa cccgagccgc acttcttcgt gcacggccgg
     6901 cgcatctgac gccgcagaca cacctttcgg aactccccac cccttggcta tcacaaagaa
     6961 caagccgaat gaatgactcg ggtggcgcat ttacgttcct tcacgagaag gtaatgcgat
     7021 agcaaagttc tggtctatat gctcaggtgt agttgtatcc gtgcggagcg tccggagggg
     7081 gcctcatgac ggctgccgtc cggcaaacca caggtgagga ccccttcacc tattccgaac
     7141 acgcatacgg atacaactag cgcattcgtc aatatgaccc gaccacaccg ctccccggca
     7201 ccgccggatg caggaggcag gccaccatgc agtccctcgt agaacacgcc cggacattca
     7261 ccgagcacgt cgccgcgaac gcaaaggatt tcgaacgttt cgcggacggc cagacccccg
     7321 aagcgctctt tgtcacgtgc tcggactcgc gtgtcgtccc ttcgctgatc accggcgccc
     7381 gcccggggca gctcttcgaa ctccgcaccg cgggcaacat cgttccgccc tacccgggcc
     7441 gggaccggcc caccggcgag gccgccacca tcgagtacgc gctgtgcgtg ctccaggtgc
     7501 gcgacatcat cgtctgcggg cactcccact gcggcgcggt gggcgcgatc ctccgcggcg
     7561 acgacctctc cgccatgccc gccgtccgcc actggctgga gcgctccacg gacggccgca
     7621 caccccccga cgacgccggc gacctccccg gcgcggtcca ggcccacgcc ctcgcccagc
     7681 tcgacaccct gcggggctac cccgcggtgc gcgagcggct cgccgagggc tccctcggcc
     7741 tgcacgcctg gtactacgaa gtgcacaccg gctccgtcag cgtgcaccgc cccgagcgcg
     7801 gcaccgagtt cgcccgcctt tgacggctct ccctccccca cgtcccgcgc gctcggcccc
     7861 ggccgggcgc gaccgtaccc acaagggaag ccatcgtgat ttccgcgaag gaactcaaga
     7921 accccacgtc gtacgacgtg acctgctggc gtcactcgtc gtcttcctgg tcgcgctgcc
     7981 gctgtgcgtc ggcgtcgccg tcgcctccgg agtcccggcc gaactgggcc tggtcaccgg
     8041 catcgtcggc ggactcgtcg tcggcctcct ccccggaagc aaactccagg tcagcggccc
     8101 tgccgccgga ctcaccgtcc tcgtcttcga agccgtcaag gagttcggcc tgagcacgct
     8161 cggcccgatc gtgctcgcgg ccggactgct ccaggtcgtg ctgggcctgg cgcgcttcgg
     8221 tcgctggttc cgcgccatct ccgtctccgt ggtgcagggg atgctcgccg gcatcggtct
     8281 gatcatcgtg ctgggccagg tgtacgccat ggccgacctc gaacagccgg gcagcggtct
     8341 cgccaagctg gccgggctcc ccggtctcgc ggcggacatc gtcacgaacc aggaggccct
     8401 gaccgccttc ggcctcggcg ccggaacggt cgcggtgctg ctgctgtggc cgaagctccc
     8461 ggcccgggtc cggatcgtcc cggcgcccct cgccgcggtc gccctggcca ccgcggtcgc
     8521 ctccctggcc gggctgcggc ccgcggtggc cgatgtcaac gggctgctga acgccatcga
     8581 tctgcccggc gggcggagtt ctcccggctc gccgatgtgg cggtcatcgg caccgtcctg
     8641 gccttcgccc tcatcgcctc ggccgagagc ctgttcagcg cggcggccat cgaccggatg
     8701 cacgacggcc cccgtaccga ctacgacaag gagctggtgg cccagggtgt cggcaacacc
     8761 ctctgcgggg cgctcggcgc cctcccgatg accgcggtca tcgtccgcag cgccgccaac
     8821 gtccaggccg gggcgaccac cgcgctctcc cgggtcgccc acggtctgtg gctgctgctc
     8881 ttcgccgcgc tcctgcccgc cgccgtcggg atcatcccgc tggccgcgct cgccggagtc
     8941 ctcgtgcacg ccgggtgcaa gctggttccc gccaaggagt tcggcccgct ctggcgcgaa
     9001 caccgtgggg aggccgtcct gttggcgatc accgcgatcg ccatcgtggt gaccaacctc
     9061 ttcgaggggt cgtgctcggc ctgctgctgg ccgtggtcaa gtcggcctgg gagacctcgc
     9121 acgtccagct caccacccat gagctcaccg gcggccgggt cgtggtgacc ctcacgggga
     9181 acgccacctt cctccggctg ccccgcatcc tggagcagtt ggagaagctc ccgcaggacc
     9241 agcccataga gctggacctc accggactgc gccacctcga ccacgcctgc cgggtcgccc
     9301 tggagaactg ggcccgccgg cacaacaacg cggagatcga accggtgacg atccgccagt
     9361 aagttccccg cccggggctt ctcgtccgga cgagaagccc cggtagcgct tcgtcgccgc
     9421 gagcgatctc gcgagggcgg gtccgtggcg agcacaacag gagccacggg ggacccgatc
     9481 gtccgccccg ccggacccag ccctgcgact tccagcgcga agcgcgtgtc cgcgtcggac
     9541 gccgtgtccc ccgccgtcgg tgatcggctt gccgttcacc agactccggc cgaccggccg
     9601 gcccgacgat cgcacatgcg agcgcctcgc tcactcgatg gtgggttctg cctccccacc
     9661 cccggtacgt ggggatcctg tgacagaggg cgcgacctgc gccggcgaaa gcgtggaggc
     9721 ggggagcggc atgacgagcg aatcgggcca cggcgaaact ctcgacgaac gtgcggtgct
     9781 gctcgtggcc ggggcggccg acctggcggt gagcgcgatc ggttcggccc tgggtgcggt
     9841 ccgagggctg ctgcgccgtt cggacaccgc cgagctggcg gcggaggccg agcatgagct
     9901 gaaggcccgg ggcggctggt gctggaccgg tacgcggccc cgccccctgc ccatctggag
     9961 atcctggccc gccaggccgt cgcacggcgg tccaccgaag atgtctgacc ggtgggacgc
    10021 ggcagcgttc aagacccggg tcgacgaggt cctgcatcag ttcgtcgccc gggaagtcga
    10081 tctgttcgcg aagatcgatc cctcactcgc tccggtggcc gcccagctgg aggccgccgt
    10141 ccaggacggc aaacggttgc gagccgcgtt ctgttactgg ggatggcggg cagtggggca
    10201 gccggacagc tccgcactgc tgcgggcggc cgcgtccctg gagctgatcc atgccgccgc
    10261 ggtcgtccat gacgacctca ttgacgacag tgctctgcgg cacggccgtc ccaccgctca
    10321 cgtcgccctg cgcggagccg tgcgacggcg tccccgttcc gcagcggccg ccaggtcgct
    10381 ggccatgctg gtcggggacc tgctgatggg gatggccggg cagttgttcg ccaccagcgg
    10441 cctgcccgcc gcctatgtgg gccgggcccg tccgctctgg tcggttctgg gccgggagct
    10501 gatcgcaggc gagtgtttgg agatcctgcg taccggaagt gagccggaca ccgatgcgtc
    10561 cctacaggtg atccggtaca agaccgccaa gtacaccgtc gagcagcctc tgttgatcgg
    10621 tggcgcgctg gccggggccg gcgggcggct gcgcgaaggc tactccgcct acggcttgcc
    10681 tctgggcgag gcgttccagc tcagggacga cctgctcggg ctgttcggag accccgagca
    10741 caccggcaag gccaacgcgg acgacgtacg cgggcaacgg cccacagcgt tgctggcgga
    10801 gacctggcgc atcgccggtg aggacgaccg gacccgtctc cgggccctcc tgggccaacg
    10861 tggcctggac gaagccgggc tccaagccgt gcgtgaggtg atgtgccggt tgagagctcc
    10921 ctctctcgtc gaagacatga tcacggcacg ggtggaggaa gctctcggcg ccctcggaga
    10981 cctcgacctt ccggcgggcc cggccgatgc gctcggcgcg ctggcgaact cggccaccgt
    11041 ccgcctgttc tgaccctcgc cactgtcggc cgcctcaacg acaaggaagc tacgtcatga
    11101 actacaccga ggcctcgatg aacgtcctgc ggcagggcgg cgacgaactg gccgacgcca
    11161 ccgtcgcggc gctcttcgag cgcggagagg tgggcaagtt caacaccctg atgcgccatg
    11221 tgtcgactac gggcacgccc cttccggacg ggctgcccga tgtcgcccgg gagtacctcc
    11281 ggaccacgag cgccccgccg gactgggtcg actgggagct gatggagaag gcccggctgt
    11341 tcttcatcga caacaacgtg cacatctcca ctgccctgtc gttcgcctcc atgccggcct
    11401 gctacgtggt tccgcacgtg gcgaggctgc tatcggccac ccacgggctg aggtacccct
    11461 ccaaacgaat ggccgagacc ggccagttca ccgtctacct gatgcaaccc gatgccttcg
    11521 aggccggtgg ccgcttcatc cccgccgccc agaaggtccg acttctgcac gcgtccatcc
    11581 gacatcacct tcagcgcgag aaccgctggg acaccagcgg gctgggaacg ccgatctgtc
    11641 aggaggacat gatcggcggg cagatgttct tctccctgct cgttctcgac agcctgcacc
    11701 gcctcggcat ccacatgtcc acggaggggg cggaggccta ctactacgcc tggcgcgtgg
    11761 tcggggcgat gctgggcgtc gaccagcaag ccgtaccccc taccctggac gacgcccgag
    11821 ccttcctgga cctgtacatg gtccggcaca tgggcccctc cgaggagggc actctgctca
    11881 cccggcagct catcgatctc tacgaggagg tcgtaccagg aaccctcttc gacccggtcg
    11941 tctccgcgct catccggcac ctcatcggcg acacctgcgc cgactggctc cgggtgcccc
    12001 gctcctcgtg ggacaccgcc gtcaaggccg tacctcacct cctcggtctc ctggagacga
    12061 tcgaggaccg ctcgccactg ggcgccaggg cactggacca cctcggccgt ctcaccaccc
    12121 ttctcgaact gtcctcgctc acccgcggac gcgtcatgca ctacgccatc cccgaacagc
    12181 tcaaggacgc atacggcgtc acccccgcct cacaccgcgc ccgccgctgg aatcccccgc
    12241 cgccacctcc tcaagctgat ccacgggccg acccgttgcc ccctgccgca cagggccctg
    12301 aaccgccttc tcctcggcgg ccatcccaca gggcgccccg ccaattccct tggtccagac
    12361 ctcttgacga ttggtctagg ccttcctagg gtcacggcaa cactgcgcga tcgccggcga
    12421 gagccctgtg ctcctggccc cgcagggttg acgggccagg gattcccctg tcccctggag
    12481 ccactcatgg agcagccttg agtacacaca tacgatggcg ccgtaccgga tccccgcgga
    12541 gcgcctcccc cggcaagcgg tccagggccg tcgcgggagc cactgcgctc ctcgtgccac
    12601 tggccgccat ggtgggcctc gcgaccccgg cgcaagcagc cgcctcggcc accgccacct
    12661 acaccaaggc atccgactgg ggcagcgggt tcgagggcaa gtggacggtg aagaacaccg
    12721 gcaccactac cctctccgcc tggaccgtcg agtgggactt cccggcgaac accaaggtca
    12781 cctcggcctg ggacgccacc gtgaccaact ccgcgaacca ctggaccgcc aagaacctcg
    12841 gctggaacgg caccctggcc ccggcgcgtc cgtctccttc ggcttcaacg gatccggctc
    12901 cggcgcaccc tccggctgca agctcaacgg caacccgtgc gacggcggct ccaccaaccc
    12961 cggcgacaac gcccctccgc tccgggcaag cccaccgcga gcgacatcac caactcctcg
    13021 gtgaagctgt cctgggcggc cgccacggac gacaagggca tcaagaacta cgacgtcaag
    13081 cgcgacggtg ccacggtcgc aaccgtcacc ggcaccacgt acaccaacac cggactgacc
    13141 gcgggcacgg actacagcta ctccgtggtg gcccgcgaca ccgccgacca gaccggaccg
    13201 gcctcggccg ccacgacggt ccgtaccacc ggtggcggag gcggcggtga gaaccccggc
    13261 ggcaacggga agatcaacct gggctacttc accaactggg gctcctacac ggtgaagaac
    13321 ctcgtgacct caggatccgc cgagaagatc acgcacatca actacgcctt cggcaacgtg
    13381 cagaacggca agtgcaccat cggcgacgcg tacgaggact acgagaagtc ctacaccgcc
    13441 gcccagtcgg tcgacggcaa ggccgacgcg tgggaccagc cgctgcgggc cacttcaacc
    13501 agctgcgcaa gctgaaggcg cagtacccgc acatcaaggt cctctggtcg ttcggcggct
    13561 ggacctggtc cggcggcttc ggccaggccg tccagaaccc cgcggccttc gcccagtcct
    13621 gctacgacct ggtcgaggac ccccgctggg ccgatgtctt cgacggcatc gacctggact
    13681 gggagtaccc caacgcctgc ggtctgacct gcgacaccag cggcccggcc gcgttcaaga
    13741 acatgatgca ggccatgcgg gccaagttcg gcccggacaa cctgctcacc gccgccatca
    13801 ccgcggacgg ctccaacggg ggcaagctcg acgccgccga ctacggaggc gccgccccgt
    13861 acatcaactg gtacgacgtg atgacgtacg actacttcgg ttcctgggcg gcgcagggtc
    13921 ccacagcccc gcactccccg ctcacctcgt accccggcat cccggcacag ggcttcaact
    13981 cggcggacgc catcgccaag ctgaaggcca agggcgtccc ggcttccaag ctgctcctcg
    14041 gcatcggctt ctacggccgc ggttggacgg gggtcactca gtcggctccg ggcggtaccg
    14101 ccacgggccc ggccgccgga atcgagcccg gcaaccagta ctacaaggtc ctcaagacgt
    14161 cgtgcccggc caccggcacg gtcggaggca cggcgtacgc ccactgcggg aacgactggt
    14221 ggagctacga caccccggcg accgtcggca ccaagatggc gtgggccaag agccagggcc
    14281 tgggcggcgc gttcttctgg gagttcaacg gtgacacggc caacggcgaa ctcgtgacgg
    14341 ccatcaacag cggcctcaag tagccccggt acgttcccgg gtccgcccgc tccccacagg
    14401 agcgggcgga cccgggaacc ggagcatccg aactcccgcg gcccggcggc cgctgatctc
    14461 gttcactgtc accctgcggc tgcgcgcggg acccggattc cgggacccgc gcgcagccgt
    14521 gccggatcag gccgcctggg cgaggagttc cgcgcggccg aagaggagcg cgtaaccggg
    14581 cggcaggcag ctgaccacct cggcgacgag gtcgtcgccg accagcgcgg cgatctggct
    14641 caggaccacc ccagcgtccc accgggcggt cgccggggtg cccccggtac gctcggcgag
    14701 ctcggcgacg aaggcggccc cggcgagctg cttcacggca ggcacttccg cggtgaacac
    14761 ccgggcggct tcctcgggca gggcggcggc gagtgcgacg cgttcgtcgc cggtgatctg
    14821 gcggccgagc gcccccagca cggcgcacag gctctcctcg gcgcgttcac gcgtggggta
    14881 ggcgccctcg taccggatct tctccaacag caggccaaag gtcgtgtcca tcggtgcgcc
    14941 ggcgttccgg ggttcgtggg tcatcgtggc ggcagccctt ctcgtccgta ctgctcgtgt
    15001 cgatgcgccg tccgcccccg cgactcgtcg tcgagcaggc gcgggggcgg acagcggtgg
    15061 atcaaagttc aggtgctctt cggatgcccg ccgaagagca ggtcataccc gggcggcagt
    15121 tgaagcagga tgcgtcgggt gagatcctcg cccgccgcct cggcggcgac tgaggacggc
    15181 tccgacgtcc caccgggcgg tctgttcgcc ggctccctcg atccaggccg cggtggcgcg
    15241 cacgaaccgt tccggggaga gcggttcggc ggcctggagc gggttgagca ggatcagagc
    15301 catggtctcc gggagccggg cggccagttc ggcccgttcc ccgcccacca ggtgggcacc
    15361 gaggagggcc aggacgacgc gcgcggcgcg ttcggcctcc ccgtgcgtct cgtactctcc
    15421 gcgttcctgg acccggtcca ggaacgcttc ccatcgcagg gtcacctcag ccgcctccca
    15481 gggtggtgcg ggcgggggcc ggaaccgggg ggaagaaggg gatctgcgtt ccggtccccg
    15541 ccgctgtcgc gggccggccc gggtcagccc ttgatctgct tgcgccggga ctccccgccg
    15601 atggcgatct tgcggggctt ggcgcgctcg gcgatcggga tgcgcagggt cagcacaccc
    15661 gcttcgtagt cggcgtcgat gcgctcggtg tcgagcgtgt ccgcgaggac gatctgccgg
    15721 gagaagacgc ccagcggacg ctcggacagc tccatctgca cgttgtcggc gttcaccgcc
    15781 ggccgacgtt cggccttgac ggtcagcatg ttccgctcga cgtcgatgtc gatcgcatcc
    15841 ggcgagacgc cgggaagatc gaaggccacc acgtactcgt cgccctcccg atacgcgtcc
    15901 atcggcatcg ccgaggggcg cgaccaggtg ccggggcgca ggagttgctc ggtgatccgg
    15961 tcgagttcac ggaaggggtc ggtacgcatc agcatgacgg aaacacctcc ggtcgatcag
    16021 gcggtcagcc cgcgcttttc acctgccacc gttgtagcat gtcatccatt cgatgacaac
    16081 tgaccgtgtc accgaaagga tgacggcatc gtcgagcgca gcgaggagcc ccctgtgacc
    16141 ccaccgaccc aacccgaacc gccccggcgt tccaccccgg acgccgtctc cttccttgcc
    16201 gcgtgggcgg ccctccagac catcgacgag gcggtccgcg acgcactcgg ccacgccggg
    16261 gacgccacct ccggtccgcc accggccacg gagcgggccg aggccctggc ctcgctccag
    16321 ctgttgcgcg aggtgcggga gcagctcgcg ggctgggaga ccggcctgat cgagacggcc
    16381 cgcgcggcgg gggcgagttg ggccgacctc gccgacccgc tgggcgtcgc gagccggcag
    16441 gcggccgagc ggcgctatct gcgcctgcgt cccggctccg agggcagcac cggggagcag
    16501 cgggtccggg cgacccggga ccgccgggcg ggagaccggt cgatcaccgc gtgggcccgg
    16561 cagcacgcgg cggatctgcg gtcgctcgcc gggcggatcg cggcgctgac cgatctcccc
    16621 gccgcggcgg acgccccgct ggaccggctc cggcaggccc tcggcaccga cgacgccgcc
    16681 gccctggtca ccccactcac cgcactgcac ccccatctcg ctccggggca cggtgagttg
    16741 gcggatcgcg tggacgcact gacgcagcac accggtcggc tgcgtgagga cacggccgcc
    16801 cgccggcgcg gcgactgacc gcacgagggc gggtccgggc acatccgccc ggacccgccg
    16861 tacgaccacg actgccggtt cctggctact gctgccgacc acggcctccg gctacggttt
    16921 gcgggcgacg agcccccact ggtcgaccgg caccgcgtcg tcctcctcgg gccgccagcg
    16981 gtcgatcggg acgaaacccg gctcgaccag ctccagcccc tcggcgcacc cagtgatctc
    17041 cgccggctcc cgcacgaggt agggcgggtt gtcgcccgac gcgtacgcct cctgcgccgc
    17101 cagcgtctgc ggggtcttca ccgtgtcaca gagcaccaga tggcttcccg acggcatccg
    17161 ggccagatac cgctggacga cctcgatgcc ctcggccggc acgaggtgcc cgagggtcga
    17221 gagcaggagc acggcgacgg gctcggacag gtcgagagtc ttcgccgcct cgtccaccac
    17281 cacgtccgtc gcggagaggt cggcgtccac gtaggccgta cggccctcgg gcgcgccggt
    17341 caggagcgcc tccgcgtggg cgaggacgat cggatcgttg tcgacgtaga cgacgcggga
    17401 caccggcgcg atgctctgcg ccacctcatg ggtgctgttc gccaccggca acccggtccc
    17461 gacgtccagg aactgacgca cgcccaccga gacgagatgg cggatcgcgc ggatctggaa
    17521 ggcgcgggag gcccgggcga tgtcggccat ctgcgggtag gccgcgctca ccgcctcggc
    17581 cagctccggt ccaccgggta gtggtccttt ccgcccagcc acgcgttcca gacgcgcgcc
    17641 gagtggggga cgtcggaccg gatgctgcgg cggaactcgt cgtcgtcggc gctcatggct
    17701 ctcctctgcc cgcttcccgt acctgacggt cgaccggacg cacgccgacc ggcccccggt
    17761 ggcgaccgta ccccgcgccc cggcaccacg caccggtgac ggagcggtca ggcccgcggg
    17821 cgctcaaaaa agccggccca cgaggccgaa gatccagctg atcagcaccg cgagcaggat
    17881 gaagatcccg acggtgatga caccgcacca cgaccagccg cctccggtgt ccagcccccg
    17941 gtcgtcccgt ccgcccagct ccccgtcgaa cagatccatg ctccacgcct cccccgtacg
    18001 cggaaccccc gtgttccgcg ggaatgcact ctcccacacc ctcacgtggc cacgatacgg
    18061 atcaggatcg tgaccatcgg cgttcagatg aggggcgtgc gctccgggcg accgcccggg
    18121 aagcccaggc cctcggccgg tgcacggtca gcgtcggcga cccggtgcac aacggcaacc
    18181 acgtccgggc cgaggctccg tggaactgtt ccacgctgcc tccgtacggt ggcgcgaaga
    18241 ccaaggtgaa cctctaccgg gacggcgtcc tggtgaagag cgccgagttc cggccgaacg
    18301 gcctgctgaa cgcccggtac ggccggcccg gccgtctccg tcggtgcggt cggatacgcg
    18361 tacgggatga cgtgcgccgc cgccgtatgc gcctcaggtc gcacacgggc gcgacgtgag
    18421 ccgatgtgcc ggacccccgc cggatccgac gatgggcgca tgaccgaacc gaccgcgggg
    18481 ctgccgttgt ccgccccgga agccctcacg gtgctcgggg cgctcgtcct cgtcctggcc
    18541 cgctggctcc ccgaccggct gcgcggcccg gccgcgctcg ccgccggagc gttgctggcc
    18601 gggtcggtga ccgtcctcgt cgcgacgggg acgcgctggc aactggtccc ggtcctcgtc
    18661 gtggcggccg ccgccggcgg gttcgcgctc gccccactgc tcgcccggcg ctccggccgc
    18721 acaccgtggc gggcccggtg gtggctcgcg gtgcccgggt cggtggtgtg cgccgccctc
    18781 gtcgcgacgg ggccggtgtc ggcgtgggcg tttcccgtac cggacttccc cgcgccgtcg
    18841 gggcgcttcc cggtgggcac cgagacggtg gagtggtcgg tgcccgcgac gcgatccgag
    18901 cgggagaagc gaccgcgtgc cgccgggccg cgcccgctcg tggtgcagct ctggtacccg
    18961 gcggggcgca gcgctccgga agcccggcgc gccccgtacc tcgggcgtac ggaggcggag
    19021 gcgcgtacgg tctcggcggc gctggccgac tacgcgggcg ttcccgggtt ccttctcgac
    19081 ggtctgccac gcgcccggag ccacgcggtg cccggcgcac cggtcgcgaa cggcggcgga
    19141 cgtttccccg tggtgctgtt ctcacccgga ctgggcggtg cgcgcaccca gaacaccgcc
    19201 tgggccgagg aactcgcctc ccacggctac gtcgtggcgg cggtcgacca cccgtacgac
    19261 tccgccgccg tggtcctctc cgacgggcgg accctccgta cccgggtcgc cgccaccggc
    19321 gaccgggcga aggaccgggc cctggcggag aagtggaccc ggacgcgggc ggcggatctg
    19381 cgcgcgatgc tcacccggct ggagcggctg gaacgcggtg gggccgaggg acggttggcc
    19441 gggcgcctcg acgtcggccg ggtcgcggcc gccgggcatt cgatcggcgg cgcggccgct
    19501 ttgcgggcgg cccgccagga cccccggttc gacgcggtcg tcgatctgga cggcttcccg
    19561 cacgggcccg tcggcggtcg cttcgagcag ccggtgctgg cgctgaccca ggagatcggg
    19621 cggggcacgg acccggacta cctgccccgg ctcacccggg tgctcgaacg gagcgacgcg
    19681 acgagctacc ggctgaccgt cccggggccg cacacctcac cttcaccgac gccccgctct
    19741 atctgccgcc ggtcccgggg atcgtgggct ccctgggccg tacggagggg catcggatca
    19801 ccgccggggc gaccctgtcc ttcctcgacg ccgccttgcg ccgcgccccc gtcgacgtgc
    19861 ccgccgcgct ctcggcccac ggggaggtga cggttcaccg gccggagggc gctcgctgag
    19921 caccccggac ccggcaggtc gaacagtgcg ccggacgcga tcttgatgac cggccggtcg
    19981 gcgagttcgc ggtgcacggg cgattcctcc ggccggggcc tcgatgggct cgcccccacg
    20041 gtcacaccgg tgcacgaccg cgttcagctc agcagcaggg cgctgtccca gggggtgacc
    20101 ggcgcacggc cgatggcgta cgtgtgcaga gccagggcga tgcccgccgc cccctccagg
    20161 aagccggggc ggtcgagcgg tcggtgcgcg agggcgtggg cgtagcggaa gccgaacggg
    20221 gccccggggt cgaatccgtc cagcacccgg gccgccaacc ggtcggcggt ggcgtggagt
    20281 tccgggtcgt cggtgtcctc ggcggtgcgc agcacgatct ggaggaggcc ggcccagccg
    20341 tggcacagcg cggagtcacg gatcgactcg tcgctcgcca ccgccagcgc accgcgcagt
    20401 gcggcctccg cgtcggcgcg ccactccggc cggtccagcg cgcttccggc gaggtggacg
    20461 gcgcgggccg caccggccgc tccgtagcac caggagtccc gaccgcgctc cggcggctcc
    20521 cccttctcga tgcgctcccg tgacatcagg tgcggccagc gcgggcccgc ctcgtcaaag
    20581 gtgcgcaggc tggtcagcag cgccatggtc cgttcgatgg cctcgtcctg gcggtccacc
    20641 cggacccccg cccgccaggc gagggcgagc agggccagtg ggccggggac accgtgggcg
    20701 aggccgaggt tgacgtgctc ggggagcccg tggtccagcc cgtcggtgat ccaccacgcg
    20761 ggcagccggg aaccgtgccg ggtgatgtcg tcggcggtgg ccacggccac gagggaggtg
    20821 agcacctcgg tcagggcggc gccggccgcc tgtcgtgcct cctgtgcgtc ggccgccagg
    20881 tggcgggcca gcagatagcg gccgatcccg gcggtgccgg cgaggacgtc gtagcggctc
    20941 cacgctccgg cgggctcccc ggcgcgggtt cgctccaggt cggcgcgggc gcgggtgcgg
    21001 acccggtcga ggatgtgccg gtccagtccg gcgagcatcg cggtgtagcc gcc
//
