LOCUS       NZ_CP021707            10999 bp    DNA     linear   CON 05-MAR-2024
DEFINITION  Streptomyces sp. S063 chromosome, complete genome.
ACCESSION   NZ_CP021707
VERSION     NZ_CP021707.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S063
  ORGANISM  Streptomyces sp. S063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Complete genome sequence of Streptomyces sp. S063, a producer of
            anti-complement compounds and various secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7614683)
  AUTHORS   Chen,L. and Zhao,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAY-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 04:19:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,905
            CDSs (total)                      :: 6,817
            Genes (coding)                    :: 6,244
            CDSs (with protein)               :: 6,244
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 574
            CDSs (without protein)            :: 573
            Pseudo Genes (ambiguous residues) :: 0 of 574
            Pseudo Genes (frameshifted)       :: 432 of 574
            Pseudo Genes (incomplete)         :: 192 of 574
            Pseudo Genes (internal stop)      :: 13 of 574
            Pseudo Genes (multiple problems)  :: 61 of 574
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:16:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 81490
            Orig. end                         :: 92489
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP021707.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Xinqing Zhao, Life Science
            and Biotechnology, Shanghai Jiaotong University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10999
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="2"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10999
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10999
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5999](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5999)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    554..568
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.26"
                     /tool="antismash"
     gene            complement(<823..1179)
                     /locus_tag="CCZ36_RS36365"
                     /pseudo=""
     CDS             complement(<823..1179)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_100089198.1"
                     /locus_tag="CCZ36_RS36365"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="integrase core domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRAPGGGLCADSVRPEPVRCSGRTRLDAFCLVARGRPAPAGAAH
                     KKIRPYRPRTSGKAERFHRTLAAEGAYQRPRTPDNERQAAFPDGPDRYDCHRPHTGPGG
                     QSPSGRVTSLSEQHT"
     gene            complement(1176..2216)
                     /locus_tag="CCZ36_RS00360"
     CDS             complement(1176..2216)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (19-269). E-value: 4.3e-12.
                     Score: 37.7. Matches aSDomain:
                     nrpspksdomains_CCZ36_RS00360_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761872.1"
                     /locus_tag="CCZ36_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_128816830.1"
                     /sec_met_domain="ADH_N (E-value: 4.7e-28, bitscore: 95.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.9e-22, bitscore:
                     78.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVAAYAAPRAKAPLERTTIERRPVGEFDILIDIKFAGICHSDI
                     HQARDGWGQGIFPMVPGHEIAGIVAETGPGVTRFKVGDRVGVGCMVDSCGQCDACLMGR
                     EQHCAEGNTQTYNALDRGGEPTYGGYSTHLVVTEKFAVNHPEGIALDEAAPLLCAGITT
                     YSPLKRWGAGPGKKVAVVGLGGLGHMAVKIAHALGAEVTVLSQSLRKKDDGLKLGADHY
                     YATSDPKTFEELAGTFDVILSTVSAPLDFGAYLGLLRTEGTLVNVGAPEEPISLNLFSL
                     ILGNRSIAGSAIGGIAETQEMLDFCAVHGLGAEIEVIEASQVNEAYERVLASDVRYRFV
                     IDTATI"
     aSDomain        complement(1410..2159)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CCZ36_RS00360_PKS_ER.1"
                     /evalue="4.30E-12"
                     /label="CCZ36_RS00360_PKS_ER.1"
                     /locus_tag="CCZ36_RS00360"
                     /protein_end="269"
                     /protein_start="19"
                     /score="37.7"
                     /tool="antismash"
                     /translation="TIERRPVGEFDILIDIKFAGICHSDIHQARDGWGQGIFPMVPGHE
                     IAGIVAETGPGVTRFKVGDRVGVGCMVDSCGQCDACLMGREQHCAEGNTQTYNALDRGG
                     EPTYGGYSTHLVVTEKFAVNHPEGIALDEAAPLLCAGITTYSPLKRWGAGPGKKVAVVG
                     LGGLGHMAVKIAHALGAEVTVLSQSLRKKDDGLKLGADHYYATSDPKTFEELAGTFDVI
                     LSTVSAPLDFGAYLGLLRTEGTLVNVGA"
     gene            2379..3305
                     /locus_tag="CCZ36_RS00365"
                     /pseudo=""
     CDS             2379..3305
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606638.1"
                     /locus_tag="CCZ36_RS00365"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDDQPEAAAPEPLDRRAELSEFLRTRRAKLQPQDVGLPDFGRHRR
                     CRGCAGGAGAAGRGVGGVLHASGAGQWAQCVGGGAGRDRACAAAHGRRARASEPSGPAG
                     PAQEEAPPGEDAARTDRAAVSPRQHGGHPRVRGRGAVRHPRLESDGCGGVRRLGRAAGG
                     RAELGPSGVPPPAYRDLFLNWDSKASDMVSYLRLYAGCHPTTRSLSALVGELSLKSEEF
                     RRLWATHNVKEKGHGVKLIRHPLVGDLTLSYETLNLPDDEDQQLVTYHAEPGSESAQAL
                     RLLASWGADARRADVISGAGRRADDER"
     gene            complement(3362..4045)
                     /locus_tag="CCZ36_RS00370"
     CDS             complement(3362..4045)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030795.1"
                     /locus_tag="CCZ36_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_128816831.1"
                     /transl_table=11
                     /translation="MTKQERATRTRQALIRSAAVVFEQHGYAQARLVLISSGAGVSTGA
                     LHFHFENKAAVAEAVVAEASQGLRDMSAAIRRRTDTALQALVDTSHALVDRLRGDPVSR
                     AGFRLSCDGERAAAPDLRMEWHHRVRELLDEAAAAGTLAHGIAREEAAAATVAVTAGFE
                     VLGRHDAEWLSPYRLTGFWQLLLPRLATAATLPLLDPAGTGAAPSTGLTPSRRSPSKRR
                     TGRRR"
     gene            complement(4251..5098)
                     /locus_tag="CCZ36_RS00375"
                     /pseudo=""
     CDS             complement(4251..5098)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060637.1"
                     /locus_tag="CCZ36_RS00375"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="NAD(P)H-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MILVTGATGAVGREVAALLAAAGPVRILARRPERVTVRGDGVEVV
                     EGAYGDRPALDRALRGVNSLFLVTNSPTEPDDERVAGRPPRRASATWSSSP"
     gene            complement(5001..5999)
                     /locus_tag="CCZ36_RS00380"
     CDS             complement(5001..5999)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060639.1"
                     /locus_tag="CCZ36_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_269467458.1"
                     /sec_met_domain="AfsA (E-value: 1.3e-25, bitscore: 87.9,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHPVGIDMVHRTRPEDAFPRNWVRLAHDRFSVAAILPHDHPFFA
                     PVGDDRHDPLLVAEAMRQAAMLAFHAGYGVPLGYHFLMADLDYVCHQDHLGVGGTPTEI
                     DVEVFCSDLKWRSGLPVQGRVGWAVHRGGELAATGMGATRFTSPKVYRRMRGDAPAEGI
                     SIPEAAPVAAARAGRSRTEDVVLSDTGREGVWELRVDTRHPTLFQRPNDHVPGMLLLEA
                     ARQAACLAAGPGGIVPAEANTRFHRYAEFGSPCWISAAVLPEEVDDTVTVQVTGHQDDE
                     PVFSTLLSGPGPTAERSLPSDSRDGCDRSGGPRGRRTAGGRRSRTDSRPPP"
     gene            6217..6855
                     /locus_tag="CCZ36_RS00385"
     CDS             6217..6855
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060641.1"
                     /locus_tag="CCZ36_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_069735029.1"
                     /transl_table=11
                     /translation="MAKQDRAIRTRQAILMAAARAFEKYGYQAATITEILKSADVTKGA
                     LYFHFPSKEDLALGVLDAQEPPQTVPEQPLKLQELIDLGMLFSHRLQTSLLARAGVRLS
                     MDQQAQGLDRSGPFLRWQEATHHLLAQAKRNGELLPHVNPTETADLYVAAFTGTQAVSQ
                     TLTDYQDLQRRHITLQQHILPSIAAPSILTALDLTPARVERLSLLASEG"
     gene            complement(6894..7859)
                     /locus_tag="CCZ36_RS00390"
     CDS             complement(6894..7859)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060643.1"
                     /locus_tag="CCZ36_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_128816832.1"
                     /transl_table=11
                     /translation="MGNAHRVAVLALDGVYPFELGIPNRVLGAADGRYSVVTCTVDGRP
                     VRTNADFSITVEHGPEVLATADTLVIPPIDTSRLTREAPADAVAALAAVRPGTRIVSIC
                     TGAFLLASAGLLDGRRATTHWAIVELFRTWYPQVRLDPGVLFVDDGDVLTSAGAASGVD
                     VCLHLVRADHGSEVANRVARLCVVPPWRDGGQAQYIEQPVPAPTANDTAATREWALRNL
                     QEPLSLASLAEHARMSRRTFVRRFNEEVGTSPGRWIVQQRVDRARHLLESTDLAVDEIA
                     GRVGFGTGASLRQHLHAAVGVTPLAYRRTFRGAVLAAGQQ"
     gene            7929..8879
                     /locus_tag="CCZ36_RS00395"
     CDS             7929..8879
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (26-313). E-value: 6.5e-52.
                     Score: 168.5. Matches aSDomain:
                     nrpspksdomains_CCZ36_RS00395_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060646.1"
                     /locus_tag="CCZ36_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_237302550.1"
                     /sec_met_domain="ADH_N (E-value: 6e-08, bitscore: 31.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.2e-16, bitscore:
                     58.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKNESMRAISQSVYGGPEVLEEVRLPRPVAGPSQIVVAVRAAGV
                     NPTDWKHRGRTMFLDRLPLVLGWDVSGVVESVGFGVTLFKPGDEVFGMLPYPYGVGSHA
                     EFTTGPARAFAHKPEGVDHVQAGALPLAALTARQALVDTADVRAGQRVLIHAAAGGVGH
                     LAVQIAKSLGAYVIGTASAAKHDFVRGLGADEVVDYRTVDFGDAVRDVDMVLDPLAGET
                     RARSLDVLRPGGTLVSLLPGGDPAEAAKAAAREIRVENLLVEADHAGMTAIADLVRAGE
                     LRAHVEAAFPLAEAAKAHALGETGRTTGKLVLVVS"
     aSDomain        8007..8867
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CCZ36_RS00395_PKS_ER.1"
                     /evalue="6.50E-52"
                     /label="CCZ36_RS00395_PKS_ER.1"
                     /locus_tag="CCZ36_RS00395"
                     /protein_end="313"
                     /protein_start="26"
                     /score="168.5"
                     /tool="antismash"
                     /translation="PRPVAGPSQIVVAVRAAGVNPTDWKHRGRTMFLDRLPLVLGWDVS
                     GVVESVGFGVTLFKPGDEVFGMLPYPYGVGSHAEFTTGPARAFAHKPEGVDHVQAGALP
                     LAALTARQALVDTADVRAGQRVLIHAAAGGVGHLAVQIAKSLGAYVIGTASAAKHDFVR
                     GLGADEVVDYRTVDFGDAVRDVDMVLDPLAGETRARSLDVLRPGGTLVSLLPGGDPAEA
                     AKAAAREIRVENLLVEADHAGMTAIADLVRAGELRAHVEAAFPLAEAAKAHALGETGRT
                     TGKLVL"
     CDS_motif       8373..8435
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CCZ36_RS00395_0001"
                     /evalue="1.90E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="CCZ36_RS00395"
                     /protein_end="169"
                     /protein_start="148"
                     /score="26.6"
                     /tool="antismash"
                     /translation="GQRVLIHAAAGGVGHLAVQIA"
     gene            complement(8930..9541)
                     /locus_tag="CCZ36_RS00400"
     CDS             complement(8930..9541)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459226.1"
                     /locus_tag="CCZ36_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysE family transporter"
                     /protein_id="WP_069735031.1"
                     /transl_table=11
                     /translation="MTNALTTAVTGFGTGLSLIVAIGAQNALVLRQGVRRDGVLAVVGI
                     CALSDALLITLGVAGVGAVVVAWPSALTVVGLLGGLFLIGYGLLAARRVLRPSALHAAD
                     APAASRRGVVLTCLAMTWLNPHVYLDTVFLLGSVAADQGPLRWTFGLGAILASLCWFVT
                     LGFGARLLSGVLARPSAWRVLDGLVAVMMIGLGTKLALGA"
     misc_feature    complement(9592..9607)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.36"
                     /tool="antismash"
     misc_feature    9595..9608
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.53"
                     /tool="antismash"
     gene            9609..10548
                     /locus_tag="CCZ36_RS36595"
                     /pseudo=""
     CDS             9609..10548
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971209.1"
                     /locus_tag="CCZ36_RS36595"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator ArgP"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMSELPLDQVRTLLAVVDEGTFDAAANVLRLTPSAVSQRVKALEQ
                     RTGRVLLMRTKPVRPTESGEVVVRFARQLARLERDARTALGMSGPGEPTSLSIAVNSDS
                     LATWFLPALRRVPQELDVAYELRREDQDHTAALLREGLVMAAVTSSPEAVTGCSVRSLG
                     RMRYLPVASPGFADRWLERRARARCAR"
     misc_feature    10545..10547
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            <10576..10800
                     /locus_tag="CCZ36_RS00410"
                     /pseudo=""
     CDS             <10576..10800
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="CCZ36_RS00410"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSLLLVEPVLPATVPADPPGGVCLTDPNMLVNVGGRERTADVFAS
                     LCAAGGFVLRSVTPLPAPNIFQITEASPA"
ORIGIN
        1 tcgcgggcat cgacaagctc cgcgaatggg cggccggtcc gccgctgaac atcggcgacg
       61 accagatcac cggtgccctc gacagtgcga ccgaccggct ccagaacagt gtcggcagcg
      121 tggtcaccac ggccgtcacc ggggtgagca ccgtggtcaa cggggtggtc acggcggttc
      181 tggcgctctt cctgatgttc ttcttcctca aggacggccc gcgcttcctc ccgtggctca
      241 cccgtcagct tcccggcagg ctcgccaccg acatccccga ggtggccgcc cgtagttggg
      301 cgaccctggg cgcgttcgtc cggtcccagg cgttcgtcgg tctgctggac gcggtcctca
      361 tcggcctcgg tctgtggatc ctcggggtgc cgttggtgct gccgctggcg gtgctgacat
      421 tcgtctgcgc gttcgtgccg atcgtggggg cgctgttcgc cgggttcgtg gcggtggtca
      481 tcgccctggt ctccaacggc ctgatggacg ccctgctcgt gctggcgatc atcgtcgtgg
      541 tgcagcagct ggagggcaat gtgttccagc ccatgatcca gagccggggg ctcggcctgc
      601 acgcggcggt cgtgctcctc gcggtgacgc tgggcggcag cctggccggg gtggtgggga
      661 gcctgctcgc cgtgccggtg gcggcggtgc tcgcggtggt ctggaactac ctccgcgaac
      721 agctcgtgga ggacccgcgg gagccggagc cggggccggg atcggaggcg gggccggggc
      781 cgggcccgag gatctgccgg aggggtcgcc cgcgccgtcg taggtgtgct gttcggacag
      841 gctggtgacg cggccggagg gtgactggcc cccgggcccg gtgtggggtc ggtggcagtc
      901 gtaccggtcc ggcccgtcgg gaaacgctgc ctgccgttcg ttgtccgggg tgcggggccg
      961 ttggtaggcc ccttccgcgg cgagggtgcg gtggaagcgt tcggccttgc cgctggtccg
     1021 gggccggtag ggccggatct tcttgtgggc ggcgccggcc ggggcgggcc gcccgcgagc
     1081 gacgaggcag aaagcgtcca ggcgcgtccg gcccgagcac ctgacgggct cgggccggac
     1141 gctgtcggcg cagaggccgc ccccgggagc gcgcgtcaga tggtcgcggt gtcgatcacg
     1201 aagcggtagc ggacgtcgct cgcgagcacc cgctcgtacg cctcgttgac ctggctcgcc
     1261 tcgatcacct cgatctcggc gccgagcccg tgcacggcgc agaagtccag catctcctgg
     1321 gtctccgcga taccgccgat cgccgaaccc gcgatcgacc ggttgcccag gatcagggag
     1381 aagaggttca gcgagatcgg ctcctcgggg gcgcccacgt tgacgagggt gccctcggtg
     1441 cgcaggagac cgaggtaggc accgaagtcc agcggggccg agaccgtgga gaggatgacg
     1501 tcgaaggttc cggccagttc ctcgaaggtc ttggggtcgc tcgtcgcgta gtagtggtcg
     1561 gcgcccagct tgagcccgtc gtccttcttc cgcagggact gggagaggac cgtgacctcg
     1621 gcgccgagcg cgtgcgcgat cttgacagcc atgtggccga gtccgccgag gccgacgacg
     1681 gcgaccttct tgcccgggcc cgcaccccag cgcttgagcg gggagtaggt ggtgatgccc
     1741 gcgcacagga gcggcgcggc ctcgtcgagg gcgatgccct cgggatggtt gacggcgaac
     1801 ttctcggtca cgacgaggtg cgtcgagtag ccgccgtagg tgggctcgcc gccgcggtcg
     1861 agagcgttgt acgtctgggt gttgccctcg gcgcagtgct gctcgcggcc catcaggcag
     1921 gcgtcgcact gtccgcagga gtcgaccatg cagccgacgc ccacccggtc gccgaccttg
     1981 aaccgggtga cgccggggcc ggtctcggcg acgatcccgg cgatctcgtg gccgggcacc
     2041 atcgggaaga tgccctggcc ccagccgtcg cgggcctggt ggatgtcgga gtggcagata
     2101 ccggcgaact tgatgtcgat caggatgtcg aactcgccca ccggacgacg ctcgatcgtg
     2161 gtccgctcca gcggggcctt ggcacgggga gcggcgtagg cggcaacggt ggtcatgccg
     2221 gaggttctcc tctgggtgat gcggtaggaa cgtgtcccag cctctctccg tgtccggcgt
     2281 ttacccaggc caccgctctg cctacgacca gtggtcctac tactgacggg gacaggctcg
     2341 gccgcatacg accacgcggc acaggaataa tggaacccat ggacgatcag ccggaggccg
     2401 ccgcacccga gccgctggac cggcgtgcgg agctcagcga gttcctgcgc acccggaggg
     2461 ccaagctcca gccgcaggac gtgggactgc ccgatttcgg ccggcaccgc cggtgccggg
     2521 gctgcgcggg aggagctggc gcagctggcc ggggtgtcgg tggcgtacta cacgcgtctg
     2581 gagcagggca atgggcgcaa tgtgtcggcg gaggtgctgg acgcgatcgc gcgtgcgctg
     2641 cggctcacgg acgccgagca cgcgcatctg aaccatctgg cccggccggc ccggcacaag
     2701 aagaagcgcc gcccggcgaa gacgcagcgc gtacggaccg ggctgctgta tctcctcgac
     2761 agcatggagg gcatccccgc gtacgtggcc ggggcgcggt ccgacatcct cgcctggaat
     2821 ccgatggctg cggcggtgtt cggcgactgg gccgcgctgc cggcggccga gcggaactgg
     2881 gcccgtctgg tgttcctccc cccgcctacc gggacctgtt cctgaactgg gactccaagg
     2941 cctcggacat ggtcagctat ctccggctgt acgcggggtg ccacccgacg acccgcagtt
     3001 tgtcggcgct ggtgggcgaa ctctcactga agagcgagga gttccggcgg ttgtgggcga
     3061 cgcacaacgt caaggagaag ggccacggcg tcaagctgat ccgtcatccg ctcgtcggcg
     3121 acctgaccct gtcgtacgaa acgctgaatc tgccggacga cgaggaccag cagctggtga
     3181 cctatcacgc ggagccgggg tcggagtcgg cgcaggccct gcgcctgctg gcgagctggg
     3241 gagccgacgc gcgccgggct gatgtgatca gcggcgcggg ccggagggcg gacgacgagc
     3301 gatgagggcc gacctcgttc caccatcggt cgattgacgg gcggtcagct tgtctccgcc
     3361 gtcagcgccg ccttcccgtc cgcctctttg acggcgaacg ccgcgagggc gtgagcccgg
     3421 tcgacggagc cgcacccgtc ccggccgggt ccaggagcgg cagggtcgcc gcggtggcga
     3481 gccggggcag cagcaactgc cagaagccgg tgagccggta cggggacagc cactcggcgt
     3541 cgtggcggcc gagcacctcg aatccggccg tcacggcgac ggtcgcggct gccgcttcct
     3601 cgcgggcgat gccgtgggcg agcgttccgg cggcggcggc ctcgtccagc agttcccgca
     3661 cccggtggtg ccactccatc cgcaggtccg gggcggcggc ccgctcgccg tcgcagctca
     3721 gccggaaccc ggcgcggctc accgggtccc cgcgcagccg gtccacgagg gcgtgcgagg
     3781 tgtcgacgag tgcttgcagg gcggtgtccg tcctgcgccg gatcgcggcg gacatgtcgc
     3841 gcagcccttg ggacgcctcc gccaccacgg cttccgcgac cgcggccttg ttctcgaagt
     3901 ggaagtgcag cgcccccgtg ctgacgcccg cgccggagct gatcagcacc agcctggcct
     3961 gggcgtaacc gtgctgttcg aagacgacgg cggcggagcg gatgagcgcc tgtcgggttc
     4021 gggtggcgcg ctcctgtttg gtcatggagt tatcaaacca acttaccggt ttcatttcca
     4081 gggaacggaa gattacgcca gaggcccttg ggcccgcttt ccggccgtgt tcgggcacgc
     4141 gagccaccgg aaacggaccg ggaaagaaga agcgcacggg gtcggcgcat tccgcagccc
     4201 gttgggcagg cgggcagtcg gcgtgctttc gcccatgcgg ggtgccgccc ctatccggcg
     4261 gcgaacgcgt ccgcgtggtc ggccgaccag gtgcggtacg acctggcccg gtgtcccgtc
     4321 agctcctgga ccgtagggac cacggccgcc ttcgcgcccg cccgctgtcg ctcggcactc
     4381 tccaggaagg catccgcgac gggccgcggg tatttcgcca gcagggccgc gcgtgcggcg
     4441 tccaggccca gttcctcgaa gcgcagcgga cgccccaaca cccgggagag ctgcgccgtc
     4501 tgttcccgcg cggtgatcgc ctccgggccc gagaccgcgt acgccctgcc ctcgtggccc
     4561 gtgccggtga gcaccgcgac ggccaccgcg gcgacgtccc gggggtcgac gcacgcgacg
     4621 ggggcgtcgc cgtacagagc gcgtaccact cccgccgagc ggatgccggg cgcccaggac
     4681 agcgtgttgg acatgaacgt cctggggcgg acgaacgtcc aggcgacccc ggactccctg
     4741 atcgcctcct cgttctcccg ctgacgtcgg gtgatgaagt cgtcggcccc cggttcctcc
     4801 accgccatca tggagagctt gaccaggtgg cggacgcccg ccgcggaggc cgcccggcga
     4861 cccgctcgtc gtcgggctcc gtggggctgt tcgtcaccag gaacagcgag ttgacgcccc
     4921 gcagggcccg gtcgagggcg gggcggtccc cgtacgcccc ctcgacgacc tcgaccccgt
     4981 ccccgcgtac cgtcacacgc tcagggcggc gggcgagaat ccgtacggga ccggcggccg
     5041 ccagcagtgc ggcgacctcg cggcccaccg ctccggtcgc acccgtcacg agaatcactg
     5101 ggaagagacc tctcagccgt cggcccgggg ccggacagga gtgtggagaa gaccggttca
     5161 tcgtcctgat gacctgtcac ctggaccgtc acggtgtcgt cgacctcttc cggcaggacc
     5221 gccgcgctga tccagcacgg gctgccgaac tcggcgtacc ggtggaaccg ggtgttggcc
     5281 tccgccggga cgatgccgcc gggacctgcc gcgaggcagg ccgcctgacg ggccgcctcc
     5341 agcagcagca tgcccgggac atggtcgttg gggcgctgga acagcgtcgg gtgccgggtg
     5401 tccacgcgta gctcccagac gccttcgcgg ccggtgtccg agagcaccac gtcctcggtc
     5461 ctgctccggc ccgcacgggc ggcggcgacc ggcgccgcct cgggtatcga tatcccctcg
     5521 gcgggggcgt cgcctcgcat ccgccggtac accttggggc tggtgaaacg ggtcgcgccc
     5581 atccctgtgg ccgccagttc cccgccccgg tgcaccgccc agcccacgcg cccctgcacg
     5641 ggcagtccgc tccgccactt caggtcggag cagaacacct ccacgtctat ctcggtgggg
     5701 gttccgccga cgcccaagtg gtcctggtgg cacacgtagt ccaggtccgc catcaggaag
     5761 tggtagccga gcggaacgcc gtacccggcg tggaaggcga gcatggccgc ctgccgcatc
     5821 gcttcggcca ccagcagcgg atcgtgccgg tcgtcgccga ccggggcgaa aaacgggtga
     5881 tcgtgcggca ggatcgccgc caccgagaac cgatcgtgcg ccagacggac ccagttgcgg
     5941 ggaaacgcgt cctccggcct ggtccggtgc accatgtcga tccccacggg atgcaccatg
     6001 tcggcctccg aatccattgc cggcaccgag tcgatcaggg ctgctgcttc gggcataact
     6061 ccccccaggg gtcatgtgat ggcgagccga ttctgcgatg cacgtgcgct gataagatac
     6121 agactcagcg gttttttttc tatccccggc agggtcgccc ctccccacac cgtcccggcc
     6181 gtttcccggg ccatccggcc cagcaaagga gacaggatgg ccaagcagga ccgggcgatc
     6241 cgcacccgcc aggcaatcct gatggcagcg gcgcgggctt tcgagaaata cggctatcaa
     6301 gccgcgacga tcaccgaaat actcaaaagc gccgacgtga cgaaaggcgc tctctacttt
     6361 cattttccgt ccaaagaaga tctcgcgctc ggtgttctcg atgcccagga gccgccgcag
     6421 accgttccgg agcagcccct caaactgcag gaactcatcg acctggggat gctgttcagc
     6481 caccgcctgc agaccagtct cctcgcccgg gcgggcgtgc gcctctccat ggaccagcag
     6541 gcacagggcc tcgaccgcag cggccctttc ctccgctggc aggaagccac ccatcacctc
     6601 ctcgcgcagg ccaaacgcaa cggtgagctg ctcccccacg tcaaccccac cgagacggcc
     6661 gacctgtacg tggccgcctt cacgggcacc caggccgtat cccagactct caccgactac
     6721 caggacctgc agcgccgcca catcacgctc cagcagcaca tacttcccag catcgccgca
     6781 ccctcgatcc tcaccgccct cgatctgacg cccgcgcgcg tcgaacgcct cagcctcctg
     6841 gcctccgagg gctgaaccgg gggccgggcc tgtgccggcc cccgcacccc cgtctactgc
     6901 tgtccggccg cgaggaccgc gccacgaaac gtacgccgat aggccagtgg ggtgacgccg
     6961 acggcggcat gcagatgctg gcgcagcgac gcgccggtgc cgaacccgac ccggcccgcg
     7021 atctcgtcca ccgccaggtc cgtggactcc aggagatgcc gggcccggtc gacccgctgc
     7081 tggacgatcc accggcccgg gctcgtgccg acctcctcgt tgaaacgtcg gacgaaggtg
     7141 cgccggctca tccgggcgtg ctcggcgagg ctcgccaggc tcagcggctc ctggaggttc
     7201 cgcagcgccc attcgcgggt cgcggcggtg tcgttcgccg tcggagcggg caccggctgc
     7261 tcgatgtact gggcctgtcc cccgtcgcgc cagggcggta cgacgcagag ccgggcgacc
     7321 cggttggcga cctcgctgcc gtggtccgcg cggacgaggt gcaggcagac gtcgacgccg
     7381 gaggccgcgc ccgccgaggt caggacgtcc ccgtcgtcga cgaagaggac gcccgggtcg
     7441 agccgcacct gggggtacca ggtgcggaag agctccacga tcgcccagtg ggtggtggcc
     7501 cgccggccgt ccagcagtcc ggccgaggcg aggaggaagg cgccggtgca gatggacacg
     7561 atgcgggtgc ccgggcgtac ggccgccagc gccgcgacgg cgtccgcggg cgcctcacgg
     7621 gtgaggcgag aggtgtcgat gggcggaatg acgagggtgt ccgccgtcgc cagcacctcg
     7681 gggccgtgtt cgacggtgat cgagaagtcg gcgttggtgc gcacgggccg gccgtccacc
     7741 gtgcaggtca cgacggagta gcggccgtcg gccgcgccga ggacccggtt cgggatgccg
     7801 agctcgaacg gatacacccc gtcgagggcg agtacggcga cgcggtgcgc gtttcccatg
     7861 gcacgatcct gtcgaaagat ggcaatcatg ccatggtacg ccgggcggac aggcgtgagg
     7921 ctggacgtat gacgaagaac gagagcatgc gcgccatcag ccagagcgtc tacggaggtc
     7981 ccgaggtact ggaggaggtc cggcttcccc ggccggtcgc gggaccgagc cagatcgtgg
     8041 tcgccgtccg ggcggccgga gtgaacccca cggactggaa gcaccggggc cggacgatgt
     8101 tcctggaccg gctgccgctc gtcctcggct gggacgtgtc cggggtcgtg gagtcggtgg
     8161 gcttcggggt gaccctcttc aagccgggcg acgaggtgtt cggcatgctg ccctacccgt
     8221 acggtgtcgg ctcccacgcc gagttcacga ccggcccggc ccgcgccttc gcccacaagc
     8281 ccgagggcgt cgaccatgtg caggcgggcg ccctcccgct cgccgccctc accgcccgcc
     8341 aggcgctggt cgacacggcg gacgtgcgcg ccgggcagcg ggtgctgatc cacgccgccg
     8401 ccggcggggt cggccatctc gccgtacaga tcgccaagtc gctgggggcg tacgtcatcg
     8461 gcaccgcgag cgccgccaag cacgacttcg tgcgcgggct cggggcggac gaggtcgtcg
     8521 actaccgcac cgtggacttc ggggacgcgg tgcgcgatgt cgacatggtg ctcgacccgc
     8581 tcgcgggcga gacccgggcg cgttcgctcg atgtcctgcg cccgggaggc acgctcgtgt
     8641 cgctgctgcc cggcggcgat ccggccgagg cggcgaaggc ggccgcgcgg gagatccggg
     8701 tggagaacct gctggtcgag gcggaccacg cgggcatgac ggccatcgcc gacctggtcc
     8761 gggccggtga gctgcgcgcc cacgtcgagg cggccttccc actggccgag gcggccaagg
     8821 cgcacgcgct gggcgaaacg ggccgcacca ccggcaagct cgtcctcgtg gtgtcgtagc
     8881 ccgcggggcg cccggcgtct cctccccgcg aggacgaggc gccgggcgtt caggcgccca
     8941 gcgccagttt cgtaccgagg ccgatcatca tgacggcgac caggccgtcc agcacccgcc
     9001 aggcggaggg gcgcgcgagg actccgctca gcagccgggc gccgaacccg agcgtcacga
     9061 accagcacag gctggcgagg atcgcgccga ggccgaaggt ccagcgcagg ggcccctggt
     9121 cggcggcgac ggacccgagc aggaacacgg tgtcgaggta cacgtgcggg ttgagccacg
     9181 tcatcgccag gcaggtcagc acgacacccc gacgcgacgc ggccggggcg tccgccgcgt
     9241 gcagggcgga cgggcgcagc acgcggcggg cggcgagcag cccgtagccg atcaggaaca
     9301 ggcctccgag cagaccgacg acggtcagcg ccgagggcca ggcgacgacg accgcgccga
     9361 cgccggcgac ccccagcgtg atgagcaacg cgtcggacag ggcgcagatg ccgaccaccg
     9421 cgagcacgcc gtcccggcgg accccctggc gcagtaccag ggcgttctgg gcgccgatgg
     9481 cgacgatgag ggagaggccg gtaccgaaac cggtgactgc ggtggtcagg gcgttcgtca
     9541 tacggccgac gctacggagc gacgcaaccc gctgtccaac taaagattct tacgtatcat
     9601 tagcattcat gatgtccgag cttcccctcg atcaggtgcg caccctgttg gccgtggtcg
     9661 acgaaggcac gttcgacgcg gcggcgaacg tactgcggct gacaccgtcg gcggtcagcc
     9721 agcgggtgaa ggcactggag caacgcacgg gccgggtgct gttgatgcgt acgaagccgg
     9781 tgcggcccac cgagtccggt gaggtggtgg tgcgcttcgc ccgccagctg gcccggctgg
     9841 agcgcgacgc gcggacggca ctcggcatgt ccgggcccgg cgaaccgaca tccctgtcga
     9901 tcgcggtgaa ctccgattcc ctggcgacct ggttcctgcc cgccctgcgg cgcgtaccgc
     9961 aggaactgga cgtcgcctac gaactgcgca gggaggacca ggaccatacg gccgccctgt
    10021 tgcgggaggg gctggtgatg gccgcggtga cctcgtcgcc ggaggcggtg acggggtgtt
    10081 cggtgcgcag tctcggccgt atgcggtatc tgccggtggc cagtcccgga ttcgccgacc
    10141 ggtggctgga gaggcgggcg cgcgcgcgtt gcgcgaggtg atcggcgacg cccggtcatc
    10201 agcttcgacc ggcgcgacga tctgcaggac gccttcgtgc gccggctcgg acccggcctc
    10261 cgggcgagcg cccggcgtca tctggtgccc acgtcggagg ggttcgtgag cgccgtggcg
    10321 gcgggcatgg gctggggcat ggtgcccgac gtccatgcga ggccgttgct gcgcgacggc
    10381 cggctggtgc tgctcgcccc ggaccacacc gtggacgtcc ccctgcactg gcagcagtgg
    10441 aggctggatt caccggcgct ggcgaccgtg gccgaggcgg tggcggcgga ggccgccgag
    10501 acgctggcgg ccggacggcc gattgccccg cgaccctttc gaagttaggt ttacctaact
    10561 caactccccg cccacggctc cctgctgctc gtcgagccgg tgctgcccgc caccgtgccg
    10621 gcggacccgc cgggcggcgt ctgcctcacc gatcccaaca tgctggtcaa cgtcggcggc
    10681 cgggaacgga cggcggacgt tttcgcgtct ctgtgcgcgg cgggcggttt cgtcctgcgc
    10741 agcgtgacgc cgctgcccgc gccgaacatc ttccagatca ccgaggcctc gccggcctga
    10801 cgggccgcgg aggtccgaag cccatgcaca ggagtacgta tgccccaccc catcgtccgc
    10861 cctccgctcc gccgcaaccg cgtcctcgcc gcgctggccg gcgggatcgc ggtcgcggtg
    10921 ggggccgggc tgctcctgtc ccacgccgcc gccacggacc cctcgggcaa caccgcgccg
    10981 gaggtcgtgc cgcccacgg
//
