LOCUS       NZ_CP025018            22286 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Streptomyces sp. M56 chromosome.
ACCESSION   NZ_CP025018
VERSION     NZ_CP025018.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. M56
  ORGANISM  Streptomyces sp. M56
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11742376)
  AUTHORS   Kim,K.K.Hyun., Klassen,J.L., Ruzzini,A.A.C., Beemelmanns,C.C. and
            Clardy,J.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2017) Leibniz Institute for Natural Product
            Research and Infection Biology - Hans Knoll Institute,
            Adolf-Reichwein-Strasse 23, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-AUG-2014
            Assembly Method                   :: HGAP v. AUG-2014
            Assembly Name                     :: M56v2
            Expected Final Version            :: yes
            Genome Coverage                   :: 94.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 06:37:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,558
            CDSs (total)                      :: 9,473
            Genes (coding)                    :: 9,167
            CDSs (with protein)               :: 9,167
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 306
            CDSs (without protein)            :: 306
            Pseudo Genes (ambiguous residues) :: 0 of 306
            Pseudo Genes (frameshifted)       :: 86 of 306
            Pseudo Genes (incomplete)         :: 261 of 306
            Pseudo Genes (internal stop)      :: 28 of 306
            Pseudo Genes (multiple problems)  :: 61 of 306
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:58:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5951393
            Orig. end                         :: 5973679
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025018.1.
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Bacteria and source DNA available from Christine Beemelmanns.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12286
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(12..27)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(522..689)
                     /locus_tag="CFP59_RS49695"
                     /old_locus_tag="CFP59_04899"
     CDS             complement(522..689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061828.1"
                     /locus_tag="CFP59_RS49695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04899"
                     /product="hypothetical protein"
                     /protein_id="WP_167459926.1"
                     /transl_table=11
                     /translation="MADATAMETSADRRRRRERFLRALNEARAVRNQVRPRQARAARMR
                     RAIHLRTFSW"
     gene            872..1507
                     /gene="upp"
                     /locus_tag="CFP59_RS24815"
                     /old_locus_tag="CFP59_04900"
     CDS             872..1507
                     /EC_number="2.4.2.9"
                     /GO_function="GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="upp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943140.1"
                     /locus_tag="CFP59_RS24815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04900"
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="WP_020870138.1"
                     /transl_table=11
                     /translation="MRIHVVDHPLVAHKLTTLRDKRTDSPTFRRLADELVTLLAYEATR
                     DVRTEQVDIETPVTATTGVRLSHPRPMVVPILRAGLGMLDGMVRLLPTAEVGFLGMIRD
                     EETLQASTYATRMPEDLSGRQVYVLDPMLATGGTLVAAIRELISRGADDVTALCLLAAP
                     QGVELMERELAGAPVTVVTSSVDERLNEQGYIVPGLGDAGDRMYGAAG"
     misc_feature    917..930
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(1648..2352)
                     /locus_tag="CFP59_RS24820"
                     /old_locus_tag="CFP59_04901"
     CDS             complement(1648..2352)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315293.1"
                     /locus_tag="CFP59_RS24820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04901"
                     /product="LytR C-terminal domain-containing protein"
                     /protein_id="WP_069861024.1"
                     /transl_table=11
                     /translation="MSMLTPPGMGGKYRITGDRYPRMSRPRSRRRLVFASFGSVMALGL
                     VGWGTLQLIDVFSGDSGDQKVRAANGTGECERGDKGPAENNAKSGRGDSGQGGQGGHGG
                     RTGGKLPKPSQITVNVYNATTRSGLAKDTAEELEKRGFKIGKVGNAPARYDKKVKSPGM
                     LLGAPGAGDGAFNVLGTQLNGAQTKNDARDGKDIDLIIGNGFKDLVKQKDADKALTALA
                     KPSPTPSGTPCH"
     misc_feature    complement(2382..2398)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            complement(2489..2788)
                     /locus_tag="CFP59_RS24825"
                     /old_locus_tag="CFP59_04902"
     CDS             complement(2489..2788)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949502.1"
                     /locus_tag="CFP59_RS24825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04902"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_014061825.1"
                     /transl_table=11
                     /translation="MIFKRIGNGRPYPDHGRESTRQWADVAPRPVRLDQLVTTKQQLDL
                     ETLLAEDSTFYGDLFAHVVKWQGDLYLEDGLHRAVRAALQQRQVLHARVLELEG"
     gene            3139..4755
                     /locus_tag="CFP59_RS24830"
                     /old_locus_tag="CFP59_04903"
     CDS             3139..4755
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061824.1"
                     /locus_tag="CFP59_RS24830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04903"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_231981384.1"
                     /transl_table=11
                     /translation="MGLPERPPEPHRASEPHRTPQPHHAPQPRRCLVTGATGYIGGRLV
                     PELLAAGHQVRCVARSPEKLRDHPWAARVETVRGDVTDEESLRAAMEGVDVAYYLVHAL
                     GTGPGFEETDRRAARIFGARARATGVRRIVYLGGLTPYGVPERALSPHLRSRAEVGRVL
                     LDSGVPTAVLRAGVIIGSGSASFEMLRYLTERLPLMVTPRWVRTRTQPIAVRDVLRLLV
                     GCATLPDEVHRAFDIGGPDVLTYGAMMQRYAEVTGLRRRLIAQVPVLTPGLSSLWVGLV
                     TPVPGAIARPLVESLRHEVVCAERDITRYVPDPPGGPLGVDRALELALRRIRDADVATR
                     WSSAATPGAPSDPLPTDPDWAGGSLYQDRRERAVDASREDVWRVVEGIGGENGWYSLPL
                     AWALRGWIDTLVGGVGLRRGRRDAARLRVGDSLDFWRVEEVRPPRLLRLRAEMRLPGLA
                     WLEMAVDGDGRGRTVYRQRALFHPRGLAGHLYWWSVAPFHALVFGGMARNIAARAEKDE
                     AGTETGGKGADGRSAPAVRMR"
     gene            complement(4798..6078)
                     /locus_tag="CFP59_RS24835"
                     /old_locus_tag="CFP59_04904"
     CDS             complement(4798..6078)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061823.1"
                     /locus_tag="CFP59_RS24835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04904"
                     /product="cytochrome P450"
                     /protein_id="WP_100806824.1"
                     /sec_met_domain="p450 (E-value: 1.3e-26, bitscore: 92.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQTQGSLVRQITDYAHRADPYPLYAELRKTPVAHDEEGPYIVST
                     YWEIHGLLHDPRLSSDARNLDPRAAPELIEEDGEEDEPGLPPSFLRLDPPEHDRLRSLA
                     MAPFGPPNTPRRLHTMRGELTRIVGELIDGFEGRDRIDLVDHFSYPFPVTVICRLLGVP
                     QEDEPRFHAWADTVAAGLDPDPDADEGAAERRRVSRQARTDLAVYLSELIEERRRAPGD
                     DMLSALVGWEGPEGRMSRVELLSTAALLLVAGHETTVNLITNGMLTLLRNPEVLARLRN
                     DPHLVVPLVEELLRFDPPVQMLPRRTPLSEIDIAGVTIPRGASVWLLLASGNRDPQRFL
                     DPDRFEPQRRDNQHLGFGSGVHSCFGAPLARLEAQIALTELARRLEGPRLLEDPPTYRR
                     NAVLRGPRHLPLAFEGLRPGGSPNGSR"
     gene            6266..6679
                     /locus_tag="CFP59_RS24840"
                     /old_locus_tag="CFP59_04905"
     CDS             6266..6679
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061822.1"
                     /locus_tag="CFP59_RS24840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04905"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_069861022.1"
                     /transl_table=11
                     /translation="MTDHDRTGGPGWPRRPRRRGQGELEAQVLVALRRAPGPVTAAWVQ
                     ERIEGELAYTTVMTILSRLHAKQAVTRERAGRSFVWRAASDEAGLAALRMRRVLDGQDD
                     REAVLASFVTGLTQDDERLLRDLLSDVAEEPEG"
     gene            6683..7630
                     /locus_tag="CFP59_RS24845"
                     /old_locus_tag="CFP59_04906"
     CDS             6683..7630
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313596.1"
                     /locus_tag="CFP59_RS24845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04906"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_079258183.1"
                     /transl_table=11
                     /translation="MGVFVFLPLVLPLTALPIARLAEQHLHPRTATRLLTLVGTVLAVC
                     STLCLGLLMVVGTAQLPGNPLPDSWSDPEVRAAVPYDVVAGKAAIGALAAVAVSCTATC
                     LRHSRVRRNAWLALAGLPESPVAVLPDDRPYAYALPGTSGRTGKPGRIVVSTGMLDSLS
                     TRERRALIAHERAHLTAHHHRYLLGAQLAARANPLLRPLRAAVDYCAERWADEEAAREV
                     GDRRVTARAVGKAALVSRGTPGPALAGFAAPGPVPRRVAALLGPVPPPRHWPPTWTAAG
                     LALWIAAVGTAASALSSANAAVALVLVLHAATPL"
     gene            complement(7767..8222)
                     /locus_tag="CFP59_RS24850"
                     /old_locus_tag="CFP59_04907"
     CDS             complement(7767..8222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675687.1"
                     /locus_tag="CFP59_RS24850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04907"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_069861020.1"
                     /transl_table=11
                     /translation="MALWDRIKESAQTMQTQLVSKKNDLKSGAFRDASMAMCALVAAAD
                     GSVDPSERQRVAQLIATNEVLQNFPADDLQRRFNDYVNKLTADFEFGKVSVMQEVAKAK
                     KKPAEARAVVQIGIVIGGADGNFDKSEQAMVREACYTLDLPPAEFDL"
     misc_feature    8252..8267
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    complement(8338..8354)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.47"
                     /tool="antismash"
     misc_feature    complement(8537..8551)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.15"
                     /tool="antismash"
     gene            8537..9709
                     /locus_tag="CFP59_RS24855"
                     /old_locus_tag="CFP59_04908"
     CDS             8537..9709
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061819.1"
                     /locus_tag="CFP59_RS24855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04908"
                     /product="acyltransferase family protein"
                     /protein_id="WP_231981385.1"
                     /transl_table=11
                     /translation="MNVSSLLPARRASASPPPEAAPASSPAPKQRDAFFDNAKYLAIVL
                     VAMGHAWEPLRGGSRAASALYMTVYTFHMPAFILISGYFSRNFDLRPDRLKRLITGIAV
                     PYVLFEVAYTFFKRWADDDPSYPISLLDPWYLTWFLIALFVWRLTTPLWRIVRWPVALA
                     LGVAALAACSPNIGDDLDLQRVLQFLPFFVVGLHMRPEHFRMIRRRAVRRLSVPVVAAA
                     LVFAYWAVPRMNPEWFYRRDSAQELGAPWWVGTVMTFALFGCSMVLTVCFLAWVPRRRM
                     WFTVLGAGTLYGYLLHGFLAKGSRFWDWYDHPWLHRPLGEIVVTAVAVAVVTALCTPPV
                     QRMFRFAMEPRMEWAFRPTGRSGGGPSEQGGSAPAVPVGAQAAGRSHGPE"
     misc_feature    8552..8554
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9769..9783)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.93"
                     /tool="antismash"
     gene            10001..12286
                     /locus_tag="CFP59_RS24860"
                     /old_locus_tag="CFP59_04909"
     CDS             10001..12286
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061818.1"
                     /locus_tag="CFP59_RS24860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04909"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_331717422.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-70, bitscore: 238.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEGSGIWEQEDLDAHDYALLCAYTHPDCSGTELSLVTDWYVWVF
                     FFDDHFLETFKRSQDRAAGKAYLDRLPAFMPMDPADGTPEPTNPVEAGLADLWARTVPS
                     MSSDWRARFRESTENLLNESLWELSNINIDRVPNPVEYIEMRRKVGGAPWSAGLVEHAV
                     RAEVPAVIAGSRPMRVLRDAFADAVHLRNDLFSYQREIEEEGELSNGVLVLETFLDCTT
                     QEAADSVNELLTSRLQQFEDTALTELGPLFAEHGLDPAACAGVLAYVKGLQDWQSGGHE
                     WHMRSSRYMNGAHEAGGAYGADGARGARGVHEAGGAHGTNGAGGTGRRSERAPWSPFAL
                     TGLGVSAASLPLTTGRAEAARARRFSHVPFQRTGPSLLPDFSMPFTLRLNAHLPTARRH
                     LVDWAHRMGILEPQPGVPGSQVWDERRLLAADLPLCAAGIHPDGSADELDVASGWLAWG
                     TYADDYYPAVFGRTHDLAGARACNARLGAFMPLDAGPTPVPANALERSLADLWGRTAGP
                     MEDAARRDLRQAIEDMTASWLWELANQTKHRIPDPVDYIEMRRHTFGSDLTMSLCRLAH
                     GRRVPPEIYRSGPVQSLESAAANYATLLNDVFSYQKEIEFEGEVHNGVLVVQNFFDCDY
                     PTGVAIVNDLMTSRMRQFQHVAEHELPVLYDDFGLGPEARKAMDGYVEELSHWMTGILN
                     WHREVPRYREEELLRVHRRPVGAGRRPVAAGAGAGARAVAPWHGPTGLGTSAARVPVPV
                     GAGLSARP"
     gene            12455..13879
                     /locus_tag="CFP59_RS24865"
                     /old_locus_tag="CFP59_04910"
     CDS             12455..13879
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061816.1"
                     /locus_tag="CFP59_RS24865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04910"
                     /product="amidase"
                     /protein_id="WP_100806826.1"
                     /transl_table=11
                     /translation="MTTTDDDLCFRTALDLGHLLRTRELSARELLEAHLARIERVNPAV
                     NAIVTLVADRAREAARQADERIVAGEELGPLHGLPIAHKDLHDTAGIRTSHGSPVVDGV
                     PDQDDLLIERIRAAGAITIGKTNVPEFGAGSHTFNPIFGATHNPYDLGRSAGGSSGGAA
                     AALASGMVPIADGSDTGGSLRNPASFCNVVGLRPSPGRVPNWPSMTAWSTLGVKGPMAR
                     TVADTALLLSAIAGPDARSPIALEEPGARFARSLDRDLTGLRVAWSPDLGGLVPVEPEV
                     AEAVAAAAEVFTGLGCVVERACPDLAEAEEVFRTLRASAFEVAFGALMDAHPDGLKRAI
                     RENAEQGRKLTGPDVARAEVLHTQLFHRVREFFGRYDVLLLPVSQVVPFDVGIEYPTEI
                     AGVAMDDYLDWMRSAYLISSTGSPALSVPAGFTPGGLPVGVQIVGPHRADFAVLQVGHA
                     FEQATGHWRRRPAGLG"
     gene            14065..15330
                     /locus_tag="CFP59_RS24870"
                     /old_locus_tag="CFP59_04911"
     CDS             14065..15330
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061815.1"
                     /locus_tag="CFP59_RS24870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04911"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_100806827.1"
                     /sec_met_domain="DAO (E-value: 9.3e-64, bitscore: 215.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTAIGPSRPPRGAVVVGAGMVGLATAWSLLNHGVEVTVVERRHP
                     AAGASWGNAGWLSPALTLPLPEPAALRYGLRGLLSPESPVYIPPRPDPRLARFLLTFTR
                     NCTPRRWRVLAGTFATLGRQALDAYDTLAADGVAEPTRPAEPCLIAFRTAAERAAMIEE
                     LEQARAAGFTIAYEPVDGDRARALEPALGDAIGAAVELHGQRYLNPGNFVRALADAVRE
                     RGGEILERTEVSGIRDLGRGVAVTTSGGQLHADVAVVATGAWLDALVRPFGVRVPVQAG
                     RGYSFSVPAEGAPTRPTYLAAQKVVCTPLGEGRVRVAGMMELAPAERPVDPRRIRAIIA
                     AARPLLRGIDWAARTDTWVGARPCTPDGLPLIGPTGSPRVYVNGGHGMWGVALGPLSGR
                     LLAEAIATGTSPAELAPLHPLR"
     gene            15453..15911
                     /locus_tag="CFP59_RS24875"
                     /old_locus_tag="CFP59_04912"
     CDS             15453..15911
                     /NRPS_PKS="Domain: Polyketide_cyc (9-126). E-value:
                     5.2e-15. Score: 47.8. Matches aSDomain:
                     nrpspksdomains_CFP59_RS24875_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009716668.1"
                     /locus_tag="CFP59_RS24875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04912"
                     /product="SRPBCC family protein"
                     /protein_id="WP_069861015.1"
                     /transl_table=11
                     /translation="MSTVRESVEVGVPLRTAYDQWTQFTEFPRFMEGVDQVIQVDDRHN
                     HWATSIAGVHREFDTEIVDQLPDERIAWRTTSGDVRQQGLVTFEPVDERHTRVNLAMVF
                     EPSGMAEKAADMTGTLDRRVKGDLRRFKDFIERRGEAEGAWRGRISPG"
     aSDomain        15480..15830
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFP59_RS24875_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="5.20E-15"
                     /label="CFP59_RS24875_Polyketide_cyc.1"
                     /locus_tag="CFP59_RS24875"
                     /protein_end="126"
                     /protein_start="9"
                     /score="47.8"
                     /tool="antismash"
                     /translation="VGVPLRTAYDQWTQFTEFPRFMEGVDQVIQVDDRHNHWATSIAGV
                     HREFDTEIVDQLPDERIAWRTTSGDVRQQGLVTFEPVDERHTRVNLAMVFEPSGMAEKA
                     ADMTGTLDRRVKG"
     misc_feature    16009..16023
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            16098..16877
                     /locus_tag="CFP59_RS24880"
                     /old_locus_tag="CFP59_04913"
     CDS             16098..16877
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043927.1"
                     /locus_tag="CFP59_RS24880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04913"
                     /product="IclR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_100806828.1"
                     /transl_table=11
                     /translation="MGAQAAPTLITSVQRAFRLMEAVGAHECGAPAKRLARETGLPLAT
                     TYHLLRTLAYEGYVHRLEDGGFVIGDKLRTLESGSRDQAMLSRIRPTLASLRDELSAAA
                     YLTFYDEGEIRVVEIVDGPQAPRVDLWVGFEDAGHATALGKCVLRELDDDARHEYLSRH
                     ELVDLTPRTVTRPGDLLRRLDSPTNSPLVADLEEYALGTVCFAVPIYYGDRLGSLGISL
                     PADRFARLAKLDPHRELFRTHLVPTASRVSRNLSLTI"
     gene            16973..18088
                     /locus_tag="CFP59_RS24885"
                     /old_locus_tag="CFP59_04914"
     CDS             16973..18088
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061812.1"
                     /locus_tag="CFP59_RS24885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04914"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_100806829.1"
                     /transl_table=11
                     /translation="MYPARLRTYDPDQMDGTGLIAPAVPVFIIIGVALLALVTSEGLGW
                     LPMLAVGPALAAAHWGPYGVMRIGLLAVGVGALLGTQGEETLRTQAIMLATPAAVALAS
                     CGASAMRQRREQVLAAVRSVAEAAQNALLTPVPAQVGEFQVAVRYSAAAAEARVGGDLY
                     ALLSTPHGVRLIVGDVRGKGLPAVSTAALVLGVFREAAYDERDLLDVVGRIERSLARNL
                     APDDFVTAVVAGYPSEGRMELVNCGHAPPLLFGESGVSAVEPTRPAPPLGLASLGGDLP
                     SLQVVPFIEGDQLLLYTDGVIEARDRGREYFPLLERVPRHICDEPSRTLASLHAELLSH
                     VGGRLHDDAALLLLRKPVLGAMRGAAEMPSM"
     gene            complement(18167..19513)
                     /gene="gdhA"
                     /locus_tag="CFP59_RS24890"
                     /old_locus_tag="CFP59_04915"
     CDS             complement(18167..19513)
                     /EC_number="1.4.1.4"
                     /GO_function="GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061811.1"
                     /locus_tag="CFP59_RS24890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04915"
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="WP_100806830.1"
                     /transl_table=11
                     /translation="MDVSARIEAVYAQIVHRNPGESEFHQAAREVLPALAPVLGAHPEY
                     VDARIVERLCEPERQLAFRVPWVDDDGEVQVNRGFRVEFSSALGPYKGGLRFHPSVNLG
                     IVKFLGFEQIFKNALTGLAIGGGKGGADFDPKGRSDGEVMRFCQSFMTELHRHLGEHTD
                     VPAGDIGVGAREIGYLFGQYKRLTNRFEAGVLTGKPVSWGGSHARTEATGYGTVHFAQE
                     MLRTRKKDFDGLTVVVSGSGNVALYAIDKVHALGGRVVACSDSSGHVVDPDGIDVTLLK
                     EIKEVRRGRIDAYATAKPGAVFSGRGSVFEVPCEVVLPCATQNELTEQCAITLVKNGVL
                     AVAEGANMPCTPAAIEIFREADVLFGPGKAANAGGVATSALEMQQNASRERWTFAQTEA
                     RLAAVMTEVHTLCRTTADRYGCSPDDYALGANAAGFVRVAEAMAAQGIV"
     gene            19944..20720
                     /locus_tag="CFP59_RS24895"
                     /old_locus_tag="CFP59_04916"
     CDS             19944..20720
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061810.1"
                     /locus_tag="CFP59_RS24895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_04916"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_100806831.1"
                     /transl_table=11
                     /translation="MNRQWRGRRTATVERTGTWHHALALDGVTREYRPGVVALHPIHLT
                     VPRGRFLAVMGPSGCGKSTLLQCAAGLDRPTAGTVRIGGTELSSLNEAALTRLRRERIG
                     FVFQAHHLVPSLTVAENVSLPLMLGGRPVEGRERRALAAVGLGDRGGALPSELSGGQCQ
                     RVAIARALVTSPDIVFADEPTGALDPAAAEEALTLLRQAVDRDGHTVVMVTHDPFAAAW
                     ADEALFLMRGKLVWRQERPEAADIRRVLKDLGGRTA"
     misc_feature    21235..21249
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
ORIGIN
        1 tgccgtccag gtcgaccagg ctgtccagat cgtcgtcggg gtcccggccc agcaactcgt
       61 cggtgagcat cgagccgtac gaggtgcggg cggccgctgc cgcgtccgat acatagatgt
      121 gcgggtcgtc ctcgccgtcc acgcggacga cgccgaacca cgcgtcttcg tgctcgatga
      181 acgccaatac cgtgtcgtca tccttcgcgg ccagacgggc cagttcgatc agatccgtca
      241 gggtttccac gtcatcgagc tctgtgtcgc tcgcttccca cccttctgcg gtgcgcgcga
      301 gcaatgcggc gaagtacacc gtgactctcc cactggtcat aggcgtgccg ggggcgggcg
      361 ggacagtgtc ccgccccaat cggaatcgtg gcagaaaccg tcgcttcgcg agaggtcttc
      421 cacgctgcgt cgtgcaccag tccaaagaga tgtggctcac gcggacggaa tcgaaacgcg
      481 cggaaaccgt ctccggcggt tcggcggaaa cgcaccaggg ctcaccagga gaacgtccgc
      541 aggtgtatcg cacggcgcat ccgggccgcg cgggcctggc ggggacgcac ctggttccgt
      601 accgccctgg cctcgttcag cgcgcgcagg aagcgttcgc gacggcggcg gcggtccgcg
      661 gaggtttcca tcgcggtcgc gtcggccatg gtcacatcac tcctcggggc cgaggtgatc
      721 gcccggcggc agcccgggcg ctcctgccca ctttcccccg aatcggcggt ttgatgccag
      781 tacggcggca gacggtcgag cgcggcgggg gcgcgcggaa gggggtcacc ggcgacagcc
      841 gggctcaggg ggctcggtta gtgtcattgc catgcggatc cacgtcgtcg accacccgct
      901 ggtggcgcac aaactcacca cgctgcgcga caagcgcacc gactccccca ccttccggcg
      961 gctcgccgac gagctggtga ccctgctcgc gtacgaggcc acccgcgatg tgcgcaccga
     1021 gcaggtcgac atcgagaccc cggtgacggc cacgaccggg gtgcggctgt cccatccgcg
     1081 ccccatggtc gtgcccatcc tgcgggccgg tctcgggatg ctcgacggca tggtgcggct
     1141 gctgcccacc gcggaggtcg gcttcctggg catgatccgg gacgaggaga cgctccaggc
     1201 gtccacctac gccacccgga tgcccgagga cctctccgga cgtcaggtgt acgtcctgga
     1261 cccgatgctc gccaccggcg gcacgctggt cgccgcgatc agggagctga tatcgcgcgg
     1321 cgccgacgat gtgaccgcgc tgtgtctgct ggcggcgccc cagggcgtcg agctcatgga
     1381 gcgcgagctt gcgggggcgc cggtgacggt ggtcacctcg tccgtcgacg agcggctcaa
     1441 cgagcagggg tacatcgtgc ccgggctcgg cgacgcgggt gaccggatgt acggggccgc
     1501 gggctgagcg cctctcaaga cgcgggctga gcgcctctcg cagggggctc ttggttggtc
     1561 ggcgcccggc tcggcgccga tctggccggc gccgagtgac ccgcgccagg tcggcgccca
     1621 cccggtgcgg gtcagcggcg gcgcaggtca gtggcagggc gttccggagg gcgtgggcga
     1681 gggcttggcc agggcggtca gcgccttgtc ggcgtccttc tgcttgacca ggtccttgaa
     1741 accgttgccg atgatcaggt cgatgtcctt gccgtcgcgc gcgtcgttct tggtctgggc
     1801 gccgttgagc tgggtgccga gcacattgaa ggccccgtcg ccggcgccgg gggcgccgag
     1861 cagcatcccg ggggacttga ccttcttgtc gtaccgggcc ggggcgttgc ccactttccc
     1921 gatcttgaag ccgcgcttct cgagctcctc ggcggtgtcc ttggcgaggc cggatcgcgt
     1981 ggtcgcgttg tagacgttca ccgtgatctg cgagggcttc ggcagcttcc cgcccgtgcg
     2041 gccgccatga ccgccctggc cgccttggcc gctgtcgccc cggccggact tcgcgttgtt
     2101 ctcggcgggg cccttgtcgc cgcgctcgca ctccccggtg ccgttcgccg cgcggacctt
     2161 ctggtcgccg ctgtcgccgg agaagacatc gatgagctga agtgttcccc agccgaccag
     2221 gccgagcgcc atgaccgagc cgaacgaggc gaacaccagt cgccggcggc tccggggtcg
     2281 gctcatccgc gggtagcgat cgcccgtaat gcggtacttt ccgcccatgc cgggaggggt
     2341 cagcatgctc atgtgcgcag cgtagtgcgg ccaggtggcg atgcctacta aatgatcaat
     2401 ggttggtgct cagaccaacc cgaaagggcc aacaaagatc ggaagtcgat cagcggcgat
     2461 cggtcaccga ggacgcgcgg gggcgtggtc agccctcgag ctccaggacg cgcgcgtgca
     2521 gcacctggcg ctgctggagc gcggcgcgca ccgcccggtg cagcccgtcc tccagataga
     2581 ggtcgccctg ccatttcacg acatgggcga agaggtcacc gtagaacgtc gagtcctccg
     2641 cgagcagcgt ctccaggtcg agctgctgct tcgtcgtgac caactggtca agacgtaccg
     2701 ggcgtggggc gacatccgcc cactggcggg tgctttcccg gccgtggtcg ggatagggcc
     2761 gaccgtttcc gatgcgcttg aagatcacac ggaaagccta ccgggccagc ccctcccggc
     2821 gcagccaagg agccctagtg ccgggcccgg ggcgggcccc gcggcccccg gaaaactgga
     2881 aaaaatgctc gaaaagggct aggcgctcat ggggggtcgg agtaacgtaa ataacagcct
     2941 gcggggcgag cgagggagct cgaccggaga gacgctcagg acagaggacg taagtccccc
     3001 ggagtgtctc ctagatggcc gggctgagag gctggaaggt cggggagacc ggaaagcgac
     3061 ctccaacacc tgatacggac aatgccgccg aagggagccc acctcgcagg ttttgtcctg
     3121 cccgcgcacc atggcgtcat gggtcttccc gagcgtccgc cggagccgca ccgcgcatcc
     3181 gagccgcacc gcacgccgca gccgcaccac gcgccgcagc cgcgccgctg tctggtcacc
     3241 ggggccaccg gctatatcgg cggcaggctg gtccccgagc tgctggccgc ggggcatcag
     3301 gtccggtgtg tggcccgctc ccccgagaag ctgcgcgacc acccctgggc ggcgcgggtg
     3361 gagaccgtac gcggcgacgt gaccgacgag gagtccctgc gcgccgccat ggagggcgtg
     3421 gacgtcgcgt actacctggt ccacgcgctg ggcaccggac ccggcttcga ggagaccgac
     3481 cgccgcgccg cccggatctt cggcgctcgg gcccgcgcca cgggggtgcg ccggatcgtc
     3541 tatctcggtg ggctgacccc gtacggcgtc cccgagcgcg cgctctcacc ccatctgcgg
     3601 tcccgggccg aggtagggcg ggtgctgctg gactccgggg tgccgacggc cgttctgcgg
     3661 gccggggtga tcatcggctc gggctctgcc tcgttcgaga tgctgcgcta tctcaccgag
     3721 cggctgccgc tgatggtgac gccccgctgg gtgcgcaccc gcacccagcc gatcgccgtc
     3781 cgcgatgtgc tgcggctgct ggtgggctgc gccacgctgc cggacgaggt gcaccgggcc
     3841 ttcgacatcg gcggccccga cgtgctcacc tacggcgcca tgatgcagcg gtacgcggag
     3901 gtgaccgggc tgcggcggcg cctcatcgca caggtcccgg tgctcacccc cgggctgtcc
     3961 agtctgtggg tcggcctggt cacgcccgtg cccggcgcca tcgcccgccc gctggtggag
     4021 tcgctgcgcc atgaggtggt gtgtgccgaa cgggacatca cccgctatgt gcccgatccg
     4081 ccgggcgggc cgctcggcgt ggaccgcgcc ctggagctgg ccctgcggcg gatccgtgac
     4141 gcggatgtgg ccacccgctg gtcctccgcc gccacccccg gcgcgcccag cgatccgctg
     4201 cccaccgacc ccgactgggc gggcggcagc ctctaccagg accgtcgcga gcgcgcggtg
     4261 gacgcctcgc gggaggacgt gtggcgggtg gtggagggaa tcggtggtga gaacggctgg
     4321 tattcgctgc cgctcgcctg ggcgctgcgc ggctggatcg acaccctggt gggcggcgta
     4381 gggctgcgcc ggggccggcg agacgcggcg cggctcagag tgggggacag cctcgacttc
     4441 tggcgggtgg aggaggtccg gccgccccgg ctgctgcggc tgcgggccga gatgcggctg
     4501 ccgggcctgg catggctgga gatggcggtc gacggggacg ggcggggccg gacggtgtac
     4561 cggcagcggg cgctgttcca tccgcgcggc ctggccgggc atctctactg gtggtcggtc
     4621 gcgcctttcc acgccctcgt cttcgggggg atggccagga acatcgccgc ccgggccgag
     4681 aaggacgagg ccgggacgga aacgggcggg aagggcgcgg acgggaggag tgcgcccgcg
     4741 gtccgcatgc ggtgaaccac gccgcggacc ccttcgccgc cgtcctgagc cccgccgtca
     4801 ccgcgacccg ttcggggatc cgcccggccg cagcccctcg aaggcgagcg gcagatgccg
     4861 tggcccgcgc agcaccgcgt tgcgccggta ggtcggcggg tcctccagca gccggggccc
     4921 ctccagccgg cgggccagct cggtcagcgc gatctgcgcc tccagccggg ccagcggtgc
     4981 gccgaagcag ctgtggacgc cgctgccgaa gccgaggtgc tggttgtccc tgcgctgggg
     5041 ctcgaatcga tcggggtcga ggaagcgctg cggatcgcgg ttgcccgagg ccagcagcag
     5101 ccagacggac gccccccggg ggatggtcac gcccgcgatg tcgatctcgg agagcggggt
     5161 gcgccgggga agcatctgca ccggcggatc gaaccgcagc aactcctcca ccagcgggac
     5221 gaccagatgg ggatcgttgc gcagccgcgc gagcacctcg gggttgcgca gcagggtcag
     5281 catgccgttg gtgatcaggt tgacggtggt ctcatggccc gccaccagca gcagcgccgc
     5341 ggtgctcagc agctccacac ggctcatccg cccctccggg ccctcccagc cgaccagggc
     5401 cgagagcatg tcgtcgccgg gtgcgcggcg gcgctcctcg atcagctcgg acagatacac
     5461 cgccagatcc gtacgggcct gccggctgac ccgccgccgc tcggcggcgc cctcgtccgc
     5521 gtccgggtcg gggtccaggc cggcggcgac ggtgtcggcc caggcgtgga agcgcggctc
     5581 gtcctcctgc ggtaccccga gcagccggca gatcacggtc accgggaagg ggtaggagaa
     5641 gtggtcgacg aggtcgatcc ggtcccggcc ctcgaagccg tcgatcagct cgccgacgat
     5701 acgcgtgagc tcaccgcgca tggtgtggag ccggcgcggg gtgttcggcg ggccgaaggg
     5761 cgccatggcg agggagcgca gccggtcgtg ctcgggcggg tccagcctca ggaagctggg
     5821 cggcagcccc ggctcgtcct cctcgccgtc ctcctcgatc agctccgggg cggcccgggg
     5881 gtccaggttg cgggcgtcgg agctgagccg ggggtcgtgc agcagaccgt ggatctccca
     5941 gtaggtggag acgatgtacg ggccctcctc gtcgtgcgcc acgggcgtct tgcgcagctc
     6001 ggcgtagagc gggtacgggt ccgcacgatg cgcgtagtcg gtgatctgcc gcacgagcga
     6061 gccttgcgtc tgcgtcatgg ctgagtgagt tccttcgtcg gggtcgtccc actgctcagc
     6121 atcggcgagg cggcccgggg ccgcgcgtac agccaggcca atggggcgaa cggacggccg
     6181 tggtccgggc gaaggaggcg gccgtccacg gctcgctacc atgaaacgcc acgcgccggg
     6241 cgcgtgcggt gtggaaggag acggtgtgac ggaccacgac cggaccggcg ggcccggctg
     6301 gccccgccgc ccccgtcggc gtggccaggg cgaactggag gcgcaggtgc tcgtggcgct
     6361 gcgccgggcg ccggggccgg tgaccgccgc atgggtgcag gagcggatcg agggcgagct
     6421 cgcctacacc acggtcatga ccatcctgtc ccggctgcac gccaagcagg ccgtgacccg
     6481 tgaacgcgcg ggccgctcct tcgtctggcg ggcggcgtcg gacgaggcgg ggctcgcggc
     6541 gctgcggatg cgccgggtgc tggacggcca ggacgaccgt gaggcggtcc tggccagctt
     6601 tgtgaccggg ctgacccagg acgacgagcg gctgctgcgc gacctgctga gcgacgtggc
     6661 ggaggagccg gagggctgac cgatgggcgt cttcgtcttc ctcccgctgg ttctgccctt
     6721 gacggcgctg ccgatcgccc ggctcgccga acagcatctc cacccgcgca ccgccacccg
     6781 gctgctgacg ctcgtcggca ccgtcctcgc ggtgtgctcc acgctgtgcc tggggctgct
     6841 gatggtcgtc ggcacggcgc agctgccggg caatccgctg ccggacagct ggtcggaccc
     6901 cgaagtacgg gccgcggtgc cctatgacgt ggtggccggg aaggcggcga tcggcgcgct
     6961 ggcggcggtg gccgtctcct gtacggccac ctgtctgcgt cactcgcggg tgcggcggaa
     7021 cgcctggctc gcgctcgccg ggctgccgga gtcgccggtc gcggtgctgc ccgacgacag
     7081 gccgtatgcg tacgccctgc ccggtacctc cgggcggacg gggaaaccgg gccggatcgt
     7141 cgtctccacc gggatgctgg acagcctcag cacccgcgag cggcgggccc tgatcgcgca
     7201 tgagcgggcc catctgaccg cgcaccacca ccgctatctg ctgggcgcgc agctcgcggc
     7261 gcgggccaac ccgctgctgc ggccgctgcg ggccgcggtg gactactgcg ccgagcgctg
     7321 ggcggacgag gaggcggccc gggaggtcgg cgaccgccgg gtcaccgcgc gggcggtcgg
     7381 caaggccgcc ctggtctcgc ggggcacgcc ggggccggcg ctcgcggggt tcgccgcgcc
     7441 ggggccggtg ccgcgcaggg tcgcggcgct gctggggccg gtgccgccgc cccggcactg
     7501 gccgccgacg tggacggcgg cggggctggc cctgtggata gcggcggtgg gcaccgccgc
     7561 gtccgcgctg tcctcggcga acgcggcggt cgccctggtc ctcgtcctgc acgcggcgac
     7621 cccgctctag gccgcgcccc tacggtctgc ggccggcggc tttgtggtct gcgggcggcc
     7681 ttacggcttg agggccgcct tacggctggt gaggccgcct cggggcttac gggaccgcct
     7741 tacggtttac cggaccgcct tacggcttac aggtcgaact cggcgggcgg gaggtccagg
     7801 gtgtagcacg cctcgcggac catggcctgc tcgctcttgt cgaagttgcc gtcggcgccg
     7861 ccgatgacga tgccgatctg gaccacggcg cgcgcctcgg cgggcttctt cttggccttg
     7921 gcgacctcct gcatcacgct caccttgccg aactcgaagt ccgcggtgag cttgttgacg
     7981 tagtcgttga agcgccgctg taggtcgtcg gccgggaagt tctgaagcac ctcgttggtg
     8041 gcgatcagct gggcgacacg ctgccgctcg gacgggtcga ccgagccgtc cgccgccgcc
     8101 accagggcac acatcgccat gctcgcatcg cggaacgcac cgctcttcaa gtcgttcttc
     8161 ttcgagacga gctgagtctg catcgtctgg gcggactcct tgatgcggtc ccacagggcc
     8221 atggccactc acactccata cggtggttag gatctacagt tgtgtagaag ctagcaggcg
     8281 gggccggtca aggcggggcg gatcggcccc cttcgtcact ctgtgaacta cccggagagg
     8341 taaacaagtt cccaagtcga ggaggtgacg gatgcgctgg gctgggcgta aacccttgta
     8401 cgcgagagct gagccttttg gggcgaggct cggcgggcgc cactatggtg catggaatgt
     8461 tccactccgc aaccctccgc cgaaacccgg aaagaggcag gatttccccc gcaggttccc
     8521 cgggaggctg tatgtgatga acgtctcgtc cttactgccc gcgcggcggg catcggcgtc
     8581 cccgcccccc gaggccgcac cggcctcgtc ccccgcgccg aaacaacgtg acgcgttctt
     8641 cgacaacgcc aagtacctgg cgatcgtgct ggtcgcgatg gggcatgcgt gggagcccct
     8701 gcgcggcggc agcagagcgg cgtccgcgct ctatatgacc gtctacacgt tccatatgcc
     8761 ggcgttcatt ctcatctccg ggtacttctc ccggaatttc gatctccggc cggaccggct
     8821 caaacgactg atcacgggta tcgccgtccc gtacgtcctc ttcgaggtcg cgtacacctt
     8881 cttcaagcgg tgggcggacg acgatccgtc ctatccgatc agtctgctcg acccctggta
     8941 tctgacctgg ttcctgatcg cgctcttcgt ctggcggctg acgacaccgc tgtggcggat
     9001 cgtgcggtgg ccggtggcgc tggctctcgg tgtcgccgcg ctcgccgcct gctcaccgaa
     9061 catcggtgac gacctcgatc tccagcgggt gctccagttc ctgcccttct tcgtggtggg
     9121 gctgcatatg cggccggagc acttccggat gatccggcgg cgcgcggtca gacggctgtc
     9181 ggtgccggtg gtcgccgccg cgctggtctt cgcctactgg gccgtaccgc ggatgaaccc
     9241 ggagtggttc taccgccggg acagcgcgca ggagctcggt gcgccgtggt gggtcggcac
     9301 ggtgatgacg ttcgccctct tcggctgctc catggtgctc accgtgtgct tcctcgcctg
     9361 ggtaccccgg cgccggatgt ggttcacggt gctcggcgcc gggacgctgt acggctatct
     9421 gctgcacggc ttcctcgcca agggctcccg cttctgggac tggtacgacc acccgtggct
     9481 gcaccggccg ctgggggaga tcgtggtgac ggcggtggcc gtggccgtgg tgaccgccct
     9541 gtgcacaccg cccgtccagc ggatgttccg gttcgcgatg gagccgcgga tggagtgggc
     9601 cttccggccg accggaagat ccggcggcgg accctccgag cagggtggct ccgcccccgc
     9661 ggtgcccgtc ggggcccagg cggccggccg ctcccacggc ccggaatgag ccgtcggcgc
     9721 gcctcctcac cgtgcggcga gggggcgcgc cgggggtggg aggcgcgcac ttgtgtgact
     9781 aatggggctt tcggataggc cggtagcggc atgggtagcc cgtagccgac cccggtccgt
     9841 agccgtcccg ctgcgggcca ccgtcgcacg gagaggtgcc ggctcagcag tgacacagcc
     9901 ctttcgactc cccgatttct acatgccgta tccggcgcgg ctgaaccccc atgtccagga
     9961 ggcacgggag cactccaccc agtgggcccg cgagatggaa atgctcgagg gctcggggat
    10021 ctgggagcag gaggatctcg acgcccacga ctacgccctg ctgtgcgcgt acacccaccc
    10081 cgactgctcc ggcacggagc tttcgctggt caccgactgg tatgtgtggg tgttcttctt
    10141 cgacgaccac ttcctggaga cgttcaagcg ctcccaggac cgtgcggccg gtaaggcgta
    10201 tctcgaccgg ctgcccgcct tcatgccgat ggatccggcc gacgggaccc ccgagcccac
    10261 caacccggtc gaggcggggc tcgcggatct gtgggcgcgg acggtgccct ccatgtcgtc
    10321 ggactggcgg gcccggttcc gggagagcac cgagaacctg ctcaacgaat cgctctggga
    10381 gctctcgaac atcaacatcg accgggtgcc caatccggtc gagtacatcg agatgcgccg
    10441 taaggtcggc ggcgcgccct ggtcggccgg gctggtcgag catgcggtgc gggccgaggt
    10501 gccggcggtg atcgccgggt cgcggccgat gcgggtgctg cgggacgcct tcgcggacgc
    10561 ggtgcacctc cgcaacgacc tgttctccta tcagcgggag atcgaggaag agggcgagct
    10621 cagcaatggt gtcctggtcc tggagacgtt cctggactgc accacccagg aggcggccga
    10681 ctccgtcaac gagctgctga cctcgcggct ccagcagttc gaggacaccg cgctcaccga
    10741 gctcggcccg ctcttcgccg agcacgggct ggacccggcg gcctgcgcgg gcgtcctcgc
    10801 ctatgtcaag gggctccagg actggcagtc gggcggccat gagtggcata tgcgctccag
    10861 ccgctatatg aacggcgcgc acgaggcggg cggggcgtat ggtgcggacg gggcgcgtgg
    10921 ggctcgcggc gtgcacgagg ccggtggcgc tcatggtacg aacggcgcgg gtggcaccgg
    10981 ccggcggagc gagcgcgctc catggtcccc cttcgcgctc accggcctcg gcgtctccgc
    11041 ggccagcctg ccgctgacca ccggccgggc ggaggcggcc agggcgcgca ggttcagcca
    11101 tgtcccgttc cagaggaccg ggccgtcgct gctgccggac ttctccatgc cgttcaccct
    11161 ccggctcaac gcgcatctgc ccaccgcccg ccgccatctg gtcgactggg cacaccggat
    11221 gggcatcctc gaaccgcagc ccggcgtccc tggttcgcag gtctgggacg agcggcggct
    11281 gctcgccgcc gacctcccgc tgtgtgcggc gggcatccat ccggacggct ccgcggacga
    11341 gctcgatgtg gcgtcgggct ggctggcctg gggcacctac gcggacgact actatccggc
    11401 ggtcttcggc cgcacccacg acctggccgg agcgagggcg tgcaacgcca ggctcggggc
    11461 gttcatgccg ctcgacgcgg gccccacccc cgtcccggcg aacgcgctgg agcgctcgct
    11521 ggccgatctg tggggccgta cggcgggccc gatggaggac gcggcgcgcc gcgacctccg
    11581 ccaggccatc gaggacatga ccgccagctg gctgtgggag ctggccaacc agacgaagca
    11641 ccggatcccc gatccggtcg actacatcga gatgcgcagg cacaccttcg gctccgacct
    11701 caccatgagc ctgtgccgac tggcgcacgg acggcgggtg ccgcccgaga tctaccgcag
    11761 cggcccggtc cagtcgctgg agagcgccgc cgcgaactac gcgacgctgc tgaacgatgt
    11821 cttctcctac cagaaggaga tcgagttcga gggcgaggtc cacaacggcg tcctcgtcgt
    11881 ccagaacttc ttcgactgcg actatccgac cggggtcgcc atcgtgaacg acctgatgac
    11941 ctcccggatg cggcagttcc agcatgtcgc cgagcatgag ctcccggtgc tgtacgacga
    12001 cttcggcctg gggccggagg ccaggaaggc gatggacggc tatgtggagg agctcagcca
    12061 ctggatgacc gggatcttga actggcaccg ggaggtcccg cgctaccggg aggaggagct
    12121 gctccgcgtc caccggcggc cggtgggggc cgggcggcgg ccggtggcgg ccggggccgg
    12181 tgcgggcgcg cgggcggtgg ccccgtggca cgggcccacc gggctcggca cctcggccgc
    12241 gcgggttccg gtgcccgtgg gagcaggtct gtcagcgcgt ccgtaaggac cgcaagcacg
    12301 tccgtaagga cctcggtcgg cgtcctcgcc ctgtccgccg ggacggggcg aggacgccgg
    12361 tgccggctct ccggagcccg acgctcttcc ctcaccccgc cgcttcccga acgatgggtt
    12421 ccgcccctgg gccccgtgag gaaggcgagc gaccgtgacg acgaccgatg acgatctctg
    12481 cttcaggacc gccctggacc tcggccatct gctgcgcacc cgcgagctgt ccgcgcgcga
    12541 gctgctcgag gcccatctgg cccgtatcga acgggtcaac cccgccgtca acgcgatcgt
    12601 caccctcgtc gccgaccgcg cccgcgaggc ggcccggcag gccgatgagc ggatcgtggc
    12661 gggagaggag ctcgggccgc tgcacgggct gcccatcgcc cacaaggacc tccacgacac
    12721 cgcgggcatc cgtaccagcc atggctcgcc ggtcgtcgac ggcgtgcccg accaggacga
    12781 tctgctgatc gaacggatcc gggccgccgg ggcgatcacc atcggcaaga ccaacgtgcc
    12841 cgagttcggg gccggttcgc ataccttcaa ccccattttc ggcgccaccc acaacccgta
    12901 cgacctgggc cgcagcgcgg gtggcagcag cggtggcgcg gcggccgcgc tggcctccgg
    12961 catggtcccg atcgcggacg gcagcgacac cggcggctcg ctgcgcaacc cggcctcgtt
    13021 ctgcaatgtg gtcggtctgc gcccgtcgcc cgggcgcgtc cccaactggc cctccatgac
    13081 cgcctggagc accctcggcg tcaaggggcc gatggcccgt accgtggccg acaccgccct
    13141 gctgctgtcc gccatcgccg gacccgacgc ccggtcgccg atcgccctgg aggagcccgg
    13201 cgcccgtttc gcccgctccc tggaccgcga tctgacgggg ttgcgggtgg cctggtcgcc
    13261 ggatctcggg gggctggtgc cggtcgagcc cgaggtggcc gaggcggtcg cggcggcggc
    13321 ggaggtcttc accggcctcg gctgcgtcgt ggagcgggcc tgtccggacc tggccgaggc
    13381 cgaggaggtc ttccgtacgc tgcgcgcctc ggcgttcgag gtcgccttcg gcgcgctcat
    13441 ggacgcgcac cccgacgggc tgaagcgggc catacgggag aacgccgagc aggggcgcaa
    13501 gctcaccggg ccggacgtcg cccgcgcgga ggtgctgcac acccagctct tccaccgtgt
    13561 ccgggagttc ttcggccgct atgacgtgct gctgctcccg gtgagccagg tggtgccctt
    13621 cgacgtcggg atcgagtacc cgaccgagat cgccggggtg gccatggacg actatctgga
    13681 ctggatgcgc tcggcgtatc tgatcagctc gaccggcagc ccggcgctgt ccgtaccggc
    13741 cgggttcacg cccggcgggc ttccggtcgg ggtgcagatc gtcgggccgc accgggcgga
    13801 cttcgcggtc ctccaggtcg gccacgcctt cgagcaggcc accgggcact ggcgacggcg
    13861 cccggcgggc ctcgggtagc ggggggccca tcagggcctc ggacagccgg ggcgatcagg
    13921 gccgcgggcg gcccggggcg atcggcgccc cgggggggcg atcacggcat ccggcagcca
    13981 gagggcgatc agggccgcgg gccggtgcgg tgcccggccc gttccaccga tgatggcgtt
    14041 tcacccatgg gaaggagcgc atccgtgccc actgccatag gtccgtcccg cccaccgcgc
    14101 ggcgccgtcg tcgtcggcgc cggcatggtc ggcctcgcca ccgcctggtc gctgctgaac
    14161 cacggcgtcg aggtcaccgt cgtggagcgg cgccaccccg cggccggggc gtcctggggg
    14221 aacgccggct ggctgtcccc ggccctgacg ctgccgctgc ccgaaccggc cgcgctccgc
    14281 tacgggctgc gcggcctgct ctcccccgag tcgcccgtct acatcccgcc ccggcccgac
    14341 ccccggctcg cccgcttcct gctcaccttc acccggaact gcaccccacg ccgctggcgg
    14401 gtcctggccg gcaccttcgc cacgctgggc cgccaggcgc tggacgcgta cgacacgctc
    14461 gcggcggacg gcgtcgccga gcccacccgg cccgccgaac cctgtctgat cgccttccgc
    14521 accgccgccg agcgggccgc gatgatcgag gagctggagc aggcccgcgc ggccggtttc
    14581 acgatcgcgt acgagccggt cgacggggac cgggcccgtg cgctggagcc cgcgctcggc
    14641 gacgccatcg gcgcggccgt cgaactccac ggccagcgct atctgaaccc ggggaacttc
    14701 gtgcgcgccc tcgccgacgc ggtgcgcgag cgcggtggcg agatcctgga gcggacggag
    14761 gtgtccggaa tccgggacct cgggcggggc gtggccgtca ccacctccgg tggccaactc
    14821 cacgcggatg tcgccgtcgt ggccaccggc gcctggctgg acgcgctggt ccgcccgttc
    14881 ggggtccggg tgccggtcca ggccggacgc ggctacagct tcagcgtgcc ggccgagggc
    14941 gcccccaccc ggcccacgta tctggccgcc cagaaggtcg tctgcacccc gctgggcgag
    15001 ggccgggtgc gggtcgccgg gatgatggaa ctggcgcccg cggaacggcc ggtggacccg
    15061 cgccggatcc gggcgatcat cgcggcggcc cgtccgctgc tgcgcggcat cgactgggcg
    15121 gcccgtacgg acacctgggt cggcgcccgc ccgtgcaccc ccgacggact gccgctgatc
    15181 ggcccgaccg gctccccgcg ggtctacgtc aacggcggcc acggcatgtg gggcgtggcc
    15241 ctcggaccgc tcagcggacg gctgctggcc gaggccatcg cgaccggcac ctccccggcc
    15301 gaactggccc cgctgcatcc gctgcgctga gccgccgcct gccgtccatc cccgctcggt
    15361 cgcacagacc gcctgggcgc ggcatgtttt ggccctgcgg tctcggaaac ccgccgtgct
    15421 gagcgtcgcg acaacgtcga aaggagccac cgatgagcac cgtgcgggag tccgtcgagg
    15481 ttggggttcc gctccgcacc gcctatgacc agtggacgca gttcaccgag ttcccgaggt
    15541 tcatggaggg cgtggaccag gtcatccagg tggacgatcg ccacaaccac tgggcgacct
    15601 ccatcgccgg tgtgcaccgg gagttcgaca ccgagatcgt ggatcagctt cccgacgagc
    15661 gcatcgcctg gcgcaccacc tccggtgatg tgcggcagca gggtctggtg accttcgagc
    15721 ccgtcgacga gcgccacacc cgggtcaatc tggccatggt cttcgagccg agcgggatgg
    15781 cggagaaggc cgcggacatg accgggacgc tcgaccggcg ggtgaagggg gatctgcgga
    15841 ggttcaagga cttcatcgag cggcgcggtg aggcggaagg cgcctggcgc ggccggatct
    15901 cacccggctg accgcgccgg tcgcatcggt cgcaccggtc tcaccgattg caccgaccgc
    15961 accggtggca cggtcgcacc ggtccacctg cccgcgagtg cacgtccgcg agggcgtcgg
    16021 ccacatcggc cggcgccctc gcccgcgtcc gacgcgcaga tcttgctcat cccctctact
    16081 aggagcaagc tggacatatg ggtgctcagg cggcgcctac gctgatcaca tccgtacagc
    16141 gggccttccg gctgatggag gcggtgggtg cgcacgagtg tggtgcgccg gccaaaaggc
    16201 tcgcccggga gacggggctg ccgctcgcca ccacgtacca cctgctgcgg acgctggcgt
    16261 acgaaggcta tgtgcaccgg ctggaggacg gcggcttcgt gatcggcgac aagctgcgca
    16321 ccctcgagtc cggcagccgg gaccaggcga tgctctcccg gatccggccg accctggcct
    16381 cgctgcgcga tgagctctcc gccgccgcct acctcacctt ctacgacgag ggcgagatcc
    16441 gggtggtgga gatcgtggac ggcccacagg cgccccgggt cgatctgtgg gtggggttcg
    16501 aggacgccgg gcacgccacc gcgctgggca aatgcgtact gcgcgagctg gacgacgacg
    16561 cccgccacga gtacttgtcc cgccatgagc tcgtcgatct cacaccgcgg accgtcaccc
    16621 gccctggcga tctgctgcgc cggctggact ccccgaccaa cagtccgctg gtcgcggacc
    16681 tggaggagta cgccctgggc acggtctgct tcgcggtgcc gatctactac ggcgaccggc
    16741 tcggctcgct cggtatctcg ctgcccgcgg accggttcgc gcggctggcg aagctggatc
    16801 cgcaccgaga gctgttccgg acccatctgg tcccgacggc gagccgggtg agcaggaacc
    16861 tctcgctcac tatctgaaaa cgcgtccctt gcgaaaccta tctaatcgct gtttctctgg
    16921 atgaaacgga cacccccggt atcactcgtg gaagagagca gcgaagcagg tcatgtaccc
    16981 ggcccgactc cgcacgtacg acccggacca gatggacggc acagggctca tcgcccccgc
    17041 ggtccccgta ttcatcatca ttggtgtggc cctgctggcc ctcgtcacct cggaggggct
    17101 cggctggctg cccatgctcg ccgtcggccc tgcgctcgcc gccgcccact gggggccgta
    17161 cggggtgatg cgcatcgggc tgctcgccgt gggggtgggt gccctgctgg gcacccaggg
    17221 tgaggagacg ctgcgcaccc aggcgatcat gctggccacg cccgccgccg tggccctggc
    17281 gagctgtggg gccagcgcca tgcgccagcg ccgtgagcag gtgctcgccg ccgttcgctc
    17341 ggtcgccgag gccgcccaga acgccctgct cacgccggtg cccgcccagg tcggcgagtt
    17401 ccaggtggcc gttcgctaca gcgccgccgc cgcggaggcg cgagtgggcg gcgatctgta
    17461 cgccctgctg tccaccccgc acggggtccg gctgatcgtc ggcgatgtgc gcggcaaggg
    17521 gctgcccgcg gtgagcaccg ccgcgctggt gctcggcgtc ttccgcgagg ccgcctacga
    17581 cgaacgcgat ctgctcgacg tcgtcggcag gatcgagcgc agcctggccc gtaacctggc
    17641 gcccgacgac ttcgtcaccg ccgtggtcgc cggttacccc agcgagggcc ggatggagct
    17701 cgtcaactgc ggacacgccc cgccgctgct gttcggcgag tcaggggtca gcgccgtcga
    17761 gcccacccgt ccggccccgc cgctcggcct ggcctccctg ggcggcgatc tgccgagcct
    17821 ccaggtggtg ccgttcatcg agggtgacca actgctgctc tacaccgacg gggtcatcga
    17881 ggcgcgggac cgcggccggg agtacttccc gctgctggaa cgggtgccgc ggcatatctg
    17941 cgacgagccg tcccgcaccc tcgcctcgct ccacgccgaa ctgctgtccc atgtgggcgg
    18001 tcggctccac gacgacgcgg cgctgctgct gctccgcaag ccggtgctgg gcgcgatgcg
    18061 cggggcggcc gaaatgccgt cgatgtgatc cgccggttgt gccgacagtg ttgtccgtat
    18121 ggcctccggc ctctgtcggt gatcggcccg gccgcgcccg accggctcag acgatgccct
    18181 gggcggccat cgcctccgcg acccgcacga acccggcggc gttcgcgccc agggcgtagt
    18241 cgtcggggga gcagccgtag cggtcggcgg tggtgcggca cagggtgtgg acctcggtca
    18301 tgacggcggc gaggcgggcc tcggtctggg cgaaggtcca gcgttcgcgg gaggcgttct
    18361 gctgcatctc cagggcggag gtggccaccc cgcccgcgtt ggcggcctta ccggggccga
    18421 agagcacatc ggcctcccgg aagatctcga tcgccgccgg ggtgcagggc atgttggcgc
    18481 cctcggccac ggccagtacg ccgttcttga ccagggtgat cgcgcactgc tcggtcagct
    18541 cgttctgggt cgcgcagggc aggacgacct cgcagggcac ctcgaagacc gagccgcggc
    18601 cggagaagac ggcgcccggc ttggcggtgg cgtaggcgtc gatccgcccc cggcggacct
    18661 ccttgatctc cttcagcagg gtgacgtcga taccgtccgg gtcgaccaca tggccggagg
    18721 agtcggagca ggccaccacc cggccgccga gggcgtggac cttgtcgatc gcgtagagcg
    18781 ccacattgcc ggatccggag acgacgaccg taaggccgtc gaaatccttc ttacgggtgc
    18841 gcagcatctc ctgggcgaag tggacggtgc cgtaacccgt ggcctcggta cgcgcgtgtg
    18901 aaccgcccca gctgaccggc ttaccggtca gcacaccggc ctcgaagcga ttggtcagcc
    18961 gcttgtactg gccgaagaga tagccgatct cacgggcgcc caccccgatg tccccggccg
    19021 gcacatcggt gtgctcgccc agatggcggt ggagttcggt catgaaggac tggcagaacc
    19081 gcatcacctc gccgtccgag cgccccttgg ggtcgaagtc cgcaccgccc ttgccgccgc
    19141 cgatggccag accggtcagc gcgttcttga agatctgctc gaagccgagg aacttcacga
    19201 tgcccagatt gacgctgggg tggaagcgca ggcccccctt gtaggggccc agcgcgctgc
    19261 tgaactccac ccggaagccg cggttgacct ggacctcgcc gtcgtcgtcc acccagggca
    19321 cccggaaggc gagttgccgc tccggctcgc acagccgctc cacgatccgg gcgtccacat
    19381 actccggatg cgcgccgagc acgggggcga gggccggcag cacctcgcgc gccgcctggt
    19441 ggaactccga ctccccgggg ttgcggtgca cgatctgcgc gtagacggcc tcgatacgag
    19501 cgctgacgtc catgggtgtc tggtgcctct ctgtggtctt ctgtcttata tgccggtcct
    19561 gtgggggtgt ccaggatctt gtccccggcg gggttcacca cggcggcgcg cccggatgtc
    19621 gcccgcggac ggggaagttc ggacgcgaga gcggacggag gaccggatgc cggacccggt
    19681 ggaaccgtgt gggggaccgg accgcggacc ggtcgcgaga ccgggcggaa ccgcgtggaa
    19741 gaccggacgc agccgtgtgg aagagcggac ggaaccgcgt ggaggacccg gcgatggtgg
    19801 agtgggcccc acccccgggc gggggtccgt accacttcca gtacgggacc gcgctctctg
    19861 ccgcgcggcc gcgcccgttt ctagcgttct cggtgacagg cggacccgtt tgatccgccc
    19921 ggacgtgacg gaggggcgga gagatgaacc ggcagtggcg cggccgcagg acggccacgg
    19981 tggagcggac ggggacctgg caccatgcgc tggccctgga cggggtcacc agggagtacc
    20041 ggccgggggt cgtggcgctg caccccatcc atctgacggt gccgcgcgga cggttcctcg
    20101 cggtgatggg gccctcgggg tgcgggaagt cgaccttgct ccagtgcgcc gccgggctcg
    20161 accggccgac ggcgggcacg gtgcgcatcg gcggcacgga gctgtcctcg ctgaacgagg
    20221 cggcgctgac ccggctgcgg cgggagcgga tcggcttcgt cttccaggcg caccatctgg
    20281 tgccgtcgct caccgtggcg gagaacgtct ccctgccgct gatgctcggc ggccggccgg
    20341 tcgaaggccg ggagcggcgg gcactcgcgg cggtcgggct gggggaccgg ggcggcgccc
    20401 tgccgtcgga gctgtccggc gggcagtgcc agcgggtggc gatcgcccgt gcgctggtga
    20461 cctcgcccga catcgtcttc gccgacgaac cgacgggggc gctcgacccc gccgccgcgg
    20521 aggaggcgct gacactgctg cggcaggccg tcgaccgtga cggccatacg gtcgtcatgg
    20581 tcacccatga cccgttcgcc gccgcctggg ccgacgaggc actttttctg atgcggggga
    20641 agctggtgtg gcggcaggag cggccggagg cggccgacat acgccgcgtc ctgaaggacc
    20701 tgggagggcg gacggcatga aggtcgccgc cctgctggcc actcgcgcca ctcgtgccca
    20761 ccgtaaggcg tggaccgcgg tcttcgccgc gctcaccctc acctccctgc tgctcggcgc
    20821 cttcgggctg actctcgtct cggcctggag cgcgcatccg cgggtggagc ggtacgccgg
    20881 ggccgatctc gtcgtggccg gcgaccagac cacccgcttc agcgcggcgt cgctgggcga
    20941 acgcgagacc gtgagcgcgg ggctcaccga gcgggtccgc atcccccgca cggcgctgac
    21001 cgtggtgcgc ggggtgccag gggtgcgggc ggccgtcgcc gacgtggaat tcccggtggg
    21061 cctcgcgggg tcggctgcca ccgagtccgc caccgagtcc gccaccgcgt ccgccaccgg
    21121 gcggccctgg gaggccgccc ggctggcctc ctacgcgcta cggacgggac gcgccccgca
    21181 gcgcgcggac gaggtggtcg tggcgggcgg tggcggcccc gaacgcggcg gggcggaccg
    21241 cgtcggccag cggctgacgc tgcgcgtggg cggtcacgac acggcgtaca ccgtcgtggg
    21301 cgtcgccgac ggcccccgta ccgccgtctg gttcaccgac gccgaggccc gccgtctgtc
    21361 cggccacccg gaggcgctgg acgccatcgg ggtcgtcgcc gaatccggca cgggcgcggg
    21421 ggagctggcc gggcgggtgc ggaaggcgct ggacacggcc ggagtcaccg acgtcgggca
    21481 ccgcgcggac ggcgacccgg ccaccgtgcg cgtcctgacc ggggacgacc ggggcgaggc
    21541 ggagttcctg gccgccgcgc cggcccgtgg tgagctgctg gcggctctgg gctccgtggc
    21601 cggagccgtc gtcctggtgt cgttgttggt ggtgtcgtcg accatcgtcc aggcgctgcg
    21661 tcaacgctcc catgaactgg gcctgttgcg ggcggtcggt gccacaccgg ggcagctgcg
    21721 cgcagcggtg ggccgggagg tggggcgggt cgcggcctgg gcggcgctgg tgggcgcggc
    21781 cggggcggcc cccgcgtacc tggggctgcg cgcgctgctg gacgcgcggg gcgcgctgcc
    21841 caccggactc gagctgacgc ttcttccgcc gctgtggctc acgccgctgg tcaccgccgc
    21901 cgtcaccgtc ctggtggccc aggccgccgc gctcatcggc ggcgccagga ccgccacggc
    21961 gcgtccggcc gaggcgctgc gcgagcgggc gccaggcagg gggcgcggta tcaccgggct
    22021 ggtgctgctg ggcgtgggcg cgagcgccgc cgggacggcc gccctccagc ggggcgcgac
    22081 cgcggcggcc gcggccggtg cggcggcggt gaccatggtg atcgcctgtg cggtgctcgg
    22141 accgtggatc gccgaggggg cgatgcggct gctgggcgct ccgctgcggc tgttcggccc
    22201 cggcggccgc ctcgccgccg ccaactgcgc ggcgtccgca caccggctgg gcgcggcgat
    22261 caccccgatc gtgctggtca ccgcgt
//
