LOCUS       NZ_CP025018            21098 bp    DNA     linear   CON 12-FEB-2024
DEFINITION  Streptomyces sp. M56 chromosome.
ACCESSION   NZ_CP025018
VERSION     NZ_CP025018.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. M56
  ORGANISM  Streptomyces sp. M56
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11742376)
  AUTHORS   Kim,K.K.Hyun., Klassen,J.L., Ruzzini,A.A.C., Beemelmanns,C.C. and
            Clardy,J.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2017) Leibniz Institute for Natural Product
            Research and Infection Biology - Hans Knoll Institute,
            Adolf-Reichwein-Strasse 23, Jena 07745, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-AUG-2014
            Assembly Method                   :: HGAP v. AUG-2014
            Assembly Name                     :: M56v2
            Expected Final Version            :: yes
            Genome Coverage                   :: 94.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 06:37:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,558
            CDSs (total)                      :: 9,473
            Genes (coding)                    :: 9,167
            CDSs (with protein)               :: 9,167
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 306
            CDSs (without protein)            :: 306
            Pseudo Genes (ambiguous residues) :: 0 of 306
            Pseudo Genes (frameshifted)       :: 86 of 306
            Pseudo Genes (incomplete)         :: 261 of 306
            Pseudo Genes (internal stop)      :: 28 of 306
            Pseudo Genes (multiple problems)  :: 61 of 306
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:58:55
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 91890
            Orig. end                         :: 112988
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025018.1.
            Annotated using prokka 1.11 from http://www.vicbioinformatics.com.
            Bacteria and source DNA available from Christine Beemelmanns.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11098](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11098)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            557..694
                     /locus_tag="CFP59_RS49400"
                     /old_locus_tag="CFP59_00086"
     CDS             557..694
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS49400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CFP59_00086"
                     /product="hypothetical protein"
                     /protein_id="WP_173963119.1"
                     /transl_table=11
                     /translation="MAIGIVELVVLATGALLLFQHMTGRRMIATTGGVAAPHDLSASVQ
                     "
     gene            complement(839..1393)
                     /locus_tag="CFP59_RS00455"
                     /old_locus_tag="CFP59_00087"
     CDS             complement(839..1393)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /locus_tag="CFP59_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00087"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_197710343.1"
                     /transl_table=11
                     /translation="MTVRKIIEQAVITLDGQISTPQDWLPTRWAGEFEQLSRDLLFSVD
                     ALLYGRVSYENHAEVWPTMEEAFGDYAVRMNTIPKHVASRTLTEVKWNATLLGDDVVDA
                     VRKLKEQPGGDILKVGTGGSFSRTLLEHGLVDEYLFWLFPVIAGSGERLYDGIDTTDFD
                     LIDVKRLTNGVLGLTYVPTAR"
     gene            1646..2389
                     /locus_tag="CFP59_RS00460"
                     /old_locus_tag="CFP59_00088"
     CDS             1646..2389
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948549.1"
                     /locus_tag="CFP59_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00088"
                     /product="flavodoxin family protein"
                     /protein_id="WP_079255594.1"
                     /transl_table=11
                     /translation="MAASPSTATPTDDAYRFDDLTALYVNCTLKPSPQQSNTQGLIDRS
                     RAIMDAHGVTTDEFRAIDHDIATGIYPDMTEHGFATDAWPTLYERVMAADILVLAGPIW
                     LGDNSSVTKRVIERLYACSSLLNDRGQYAFYGRIGGCLITGNEDGVKHCAMNVLYSLQH
                     LGYTIPPQADAGWIGAVGPGPSYLDPNSGGPENDFTNRNTAFMTWNLMHLGAMLKRADG
                     IPAHGNQRSEWEAGCRFDYPNPDYR"
     gene            complement(2454..3080)
                     /locus_tag="CFP59_RS00465"
                     /old_locus_tag="CFP59_00089"
     CDS             complement(2454..3080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059113.1"
                     /locus_tag="CFP59_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00089"
                     /product="RraA family protein"
                     /protein_id="WP_079255595.1"
                     /transl_table=11
                     /translation="MASDLKPVPDRVSCASLVDAMGRVHGHRAHIVGLVSPAPRKLFGP
                     AATIAYLPYRDDIPHAEFGDLFGQAVGDRPAGTVLVLSSGGYSDVSHGGGTKLSRLEHT
                     HAAGVLADGRLRDFGQLGAYGFATWCRGEATRWGGDIAMPYAVNVAVEVGGVCVVPGDY
                     VYADASGAVVIPGGSLRRVIDEALKIEAEDARTAEGILGEYRPPS"
     misc_feature    complement(3235..3253)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.3"
                     /tool="antismash"
     misc_feature    complement(3236..3252)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.68"
                     /tool="antismash"
     misc_feature    3263..3281
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            3328..4449
                     /locus_tag="CFP59_RS00470"
                     /old_locus_tag="CFP59_00090"
     CDS             3328..4449
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328517.1"
                     /locus_tag="CFP59_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00090"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_059143095.1"
                     /transl_table=11
                     /translation="MQFGIFTVGDVTTDPTTGTAPTEAERIRATVAIARKAEEAGLDVF
                     ATGEHHNPPFVPSSPTTLLGYIAGQTERIILSTSTTLITTNDPVKIAEDFSVLQHLSGG
                     RTDVMLGRGNTGPVYPWFGQDIRQAVPLTVEHYGLLRRLWREEVVDWEGKLRSALQGFT
                     LVPRPLDDIPPFVWHGSIRTPEVAELAAYFGDGFFANHIFWPTSHTQSMVRMYRRRFAH
                     YGHGAPEQAIVGLGGQVFMRRNSQEAVDEFRPYFDNAPVYGHGPSLEDFTTLTPLTVGS
                     PAQVIERTLGFRDYTGDYQRQLFLVDHAGLPLKTVLEQLDLLGEEVVPVLRKEFAVGRP
                     ADVPPAPTHESLLRARRSEEKPPSDEEEGPEAR"
     gene            4446..5087
                     /locus_tag="CFP59_RS00475"
                     /old_locus_tag="CFP59_00091"
     CDS             4446..5087
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018548810.1"
                     /locus_tag="CFP59_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00091"
                     /product="CE1759 family FMN reductase"
                     /protein_id="WP_059142961.1"
                     /transl_table=11
                     /translation="MKLAIITGGLREPSSTRLLADRLATAVTRELEQHGEQVEASFVEL
                     RPLGHLIMDAMLTGFTKDELESAFRTVADADGIIAVTPAFNASFSGLFKSFFDVLPEQT
                     LSDLPVLIGATGGTERHSLVLEHALRPMLTYLHAIVSPRAVYAATSDFGSPTGAALAER
                     ITDAAADFSRLLRACGPRVRREPADEDLASMQRLLGDTTGVGPGRPTDPT"
     gene            complement(5173..7779)
                     /gene="rph"
                     /locus_tag="CFP59_RS00480"
                     /old_locus_tag="CFP59_00092"
     CDS             complement(5173..7779)
                     /EC_number="2.7.9.6"
                     /codon_start=1
                     /gene="rph"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059129.1"
                     /locus_tag="CFP59_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00092"
                     /product="rifamycin-inactivating phosphotransferase"
                     /protein_id="WP_100804509.1"
                     /sec_met_domain="PPDK_N (E-value: 3.7e-88, bitscore: 295.0,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERYVLDLREVAETQVAVVGGKGGHLGGLSRIEGIRVPDGFCVT
                     TDAFRQIMAEVPSIDDQLDQLARVNPDDREAIRTLSARIRRTIEGIAIPGDLAGAITRA
                     LGRHGEQAAYAVRSSATAEDLPTASFAGQQDTYLNVVGPTAILQHISRCLASLFTERAV
                     IYRRRGGIDHRTVHMAVVVQRMVCPDAAGILFTADPVTGNRKVATVDAGFGLGEALVSG
                     LVNPDVFTVRHGEIVARTIAAKQRAVHALPDGGTREAAIDARRQEQPALTDAQVVRLVE
                     LGRRIEAHFGRPQDIEWCLVDDDFQIVQSRPITTLFPIPESGDQENHVYLSVGHQQMMT
                     DPMKPLGISVWQLTAMAPMHEAGGRLFVDATRRLASPASRAALLDVVGRGDPLIRDALE
                     TVLERDDFVPSLPDAGPGGPPARGVSAPIETDPAIVTGLIERSRTSIAALERDIRTKTG
                     PALFDFLREAFEEHKRVLTDPLSMQAIMAGMEATWWLNDTLREWLGEKNAADTLTLSAP
                     DNVTSEMGLALLDVADVIRPHPEVVAFLRGVESIEDDAFLDELAKLAGGAEARDAIESY
                     LDRYGMRCVGEIDITRPRWRERPTTLVPVILDNVRNFEPGAAGRRFEQGRQKAREKERD
                     VLSRLRALPDGDRKADEAKRMIDRVRTFIGYREYPKYGIISRYFVYKRALLAEAERLVE
                     AGVLPEQEDIFYLTFQELHDVVRSHQVDDRLIQQRKDAFRSYHALTPPRVLTSDGEAVT
                     GAYRRDDAPAGALIGLPVSAGTIEGRARVILDMGEADLEAGDILVTAFTDPSWSPLFVG
                     IAGLVTEVGGLMTHGAVIAREYGLPAVVGVERATRLIRDGQRIRVHGTDGYVEILP"
     misc_feature    complement(7989..8004)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            <8514..>8708
                     /locus_tag="CFP59_RS50425"
                     /pseudo=""
     CDS             8514..>8708
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000012: Monooxygenation (85% identity)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059132.1"
                     /locus_tag="CFP59_RS50425"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRCLHGSAMGWESRVRYAAGQARNDLGSGAVLVRPDGVVAWAGER
                     HPDREAFERAAVQWYGSPGA"
     gene            complement(8763..9926)
                     /locus_tag="CFP59_RS00490"
                     /old_locus_tag="CFP59_00093"
     CDS             complement(8763..9926)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019066651.1"
                     /locus_tag="CFP59_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00093"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_069870775.1"
                     /transl_table=11
                     /translation="MTYTEASMDALRQAGDELADATVATLFERGEVGKFNTLMRYVSTV
                     GAPLPDGLPDVAREYLRATSAPPAWVDWGEMEKARLFFIDNNVHISTALSFASMPACYL
                     VPRVAKLLSATHGLKYPSKRMAETGQFTVYLMQPGAFEAGSRFIPAAQKVRLLHASIRH
                     HLRRENRWDADALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSTEGAEAYYYAWRVV
                     GAMLGVDQDVVPTTLDDARRFLDLYMVRHMGPTEEGAHLTRQLIDLYEEVVPGTFFDPI
                     VSALIRHLVGDTCADWLQVSRTPWDAVVKAVPHLLGVLETIEDRSPLGAWALDRLGHLT
                     TILELSSLTRGRVMHYAIPEQLRKDYGIPGTVPRTHRWTPPAATVSP"
     gene            complement(10001..11098)
                     /locus_tag="CFP59_RS00495"
                     /old_locus_tag="CFP59_00094"
     CDS             complement(10001..11098)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059134.1"
                     /locus_tag="CFP59_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00094"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_100804510.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-35, bitscore:
                     121.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRRGSDRWGPDRWGSDRWRPVAFKTRVDEVLHGFVAQEAEQLS
                     AIDPALGPVAGQLEAAVADGKRLRAAFCYWGWRAVGQSDSDALVRAAASMELVHAAAVV
                     HDDLIDDSPLRHGRPTAHIALRAAVRRRPRAVAAARSLAMLVGDLLMSLAGQMFATSGL
                     PAAYLARARPLWSVLARELIAGECLEILRTGADPDTTASLKVIRYKTAKYTVEQPLLIG
                     GALAGAGRRLREGYSAYGLPLGEAFQLRDDLLGLFGDPERTGKENADDVRGHRPTALLA
                     ETWRIAGDGERERLSALLGRRDLDAEGLDAVREVMSRLKAPDRIEAMITARVEEALDAL
                     HELDTPPYAAAALTALARSAAVRLS"
     misc_feature    complement(10967..10969)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11091..11372)
                     /locus_tag="CFP59_RS00500"
                     /old_locus_tag="CFP59_00095"
     CDS             complement(11091..11372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059135.1"
                     /locus_tag="CFP59_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00095"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_069870780.1"
                     /transl_table=11
                     /translation="MAQGTGRRGGLDERAVLLAAGLADLAVSTLGSVLGAARGLLRRSD
                     AAELAAEAEHDLMARGRLALERHTAAVPPAHLEILARHALARRAAGDV"
     gene            complement(11535..12230)
                     /locus_tag="CFP59_RS00505"
                     /old_locus_tag="CFP59_00096"
     CDS             complement(11535..12230)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.4"
                     /locus_tag="CFP59_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00096"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_231981071.1"
                     /transl_table=11
                     /translation="MHKASGKLLTPGGGYVENDRTLLAAALREVCEETGLRPDDLCLTP
                     QLLGKALDIDVHDIDANPAKGEPAHQHYDFRYVFYLMPDRAPVLELQDEEVSGARWLGF
                     SDVRSPTLRAKLLAAKAQGLDGQPQPVNASALIHDGQGRYLLHLRDQREGIGLPGCSPC
                     WAVAPAAQPASYVRIRGRVVRVTTEGAAEHIEALAQKYLGGSYPWFGGRDQVRVLYVIQ
                     PERISSPRG"
     gene            complement(12592..>12780)
                     /locus_tag="CFP59_RS00510"
                     /pseudo=""
     CDS             complement(12592..>12780)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012606252.1"
                     /locus_tag="CFP59_RS00510"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RIARKGIESSKRLGRHRWTIERTMSWLAGCRRLHRRYERKAVHFL
                     AFTSIACTLICYRRLTK"
     misc_feature    complement(12821..12834)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            complement(12832..14033)
                     /locus_tag="CFP59_RS00515"
                     /old_locus_tag="CFP59_00097"
     CDS             complement(join(12832..13742,13742..14033))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611170.1"
                     /locus_tag="CFP59_RS00515"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CFP59_00097"
                     /product="IS3 family transposase"
                     /protein_id="WP_100804488.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MVMKNYPPQFKADAVALYQSRPGATIRQVAADLGINPETLRNWVR
                     AAGASRPRGRRAEAPAEQPTPLEAENAALRKKVRELEEEREILRKAAKYFAGGDALVNR
                     FQFVADHQRRYGVKRLCTILGIARSSFYYWRRTAADRAARQAADARLATRIRAVHHESG
                     GTYGVPRITAELRDDGERVNHKRIARVMRSIGLAGVRLRRRHRTTVADPAAAKAPDLIG
                     RDFTASEPNTKYVGDITYLPLEGGKFLYVATVIDLASRRLAGWAIADHMRTDLVTDALA
                     AAERTRGSLAGAVMHTDHGAQYTSRAFADACRQAGVRQSMSAIGSSADNALAESFNATF
                     KRETLQGRKTWSSERDARLDAFGWLNRYNTRRRHSRLGQRSPIAYETALDTTSTTLAQA
                     A"
     gene            complement(14432..15340)
                     /locus_tag="CFP59_RS00520"
                     /old_locus_tag="CFP59_00099"
     CDS             complement(14432..15340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144158.1"
                     /locus_tag="CFP59_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00099"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_231981704.1"
                     /transl_table=11
                     /translation="MQASTITLGNVTISRVVEYTGPVGMTSREFFPDSPEKLWRQNRSW
                     LSPDFWNPNTDAVRIALQTWVLRSEGRTILIDTGAGNDKFRPYAKTWQYLDAGFLRRLS
                     RAGVRPQDVDIVVNTHLHNDHVGWNTRREGRDWVPTFPNATYLIPETEFTFWTPEHRSK
                     AKDPKAALNVWEDSILPVHQAGLVKLWDGSHTIDGNLTLDLAPGHTPGSSVVRLQSGGD
                     RAVFAGDLLHTPLQLEHPEFDSCFEEDEKQARMTRRRTLEWTADRKVLLLPEHLPGHGA
                     VEIARNGSHFVIKKWAGFSRI"
     misc_feature    complement(15306..15316)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            complement(15962..16873)
                     /locus_tag="CFP59_RS00525"
                     /old_locus_tag="CFP59_00100"
     CDS             complement(15962..16873)
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (28-271). E-value:
                     3.5e-23. Score: 74.4. Matches aSDomain:
                     nrpspksdomains_CFP59_RS00525_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01250.1"
                     /locus_tag="CFP59_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00100"
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="WP_159398792.1"
                     /sec_met_domain="PF00561 (E-value: 3.1e-18, bitscore: 65.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.7e-16, bitscore:
                     60.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSIRITEGRIPVPGGNVWYRRMGRGGVPLLLVHGGPGYPSDVLF
                     EAFEPLAREREIVWYDQLGVGRSDPIDDPLLLTVDRFLDELGAVTEGLGLDRAHVYGHS
                     WGAMLGLQFAARRGPEWTSLVCANGPASVPRFMEEVRELLAGLPGNVLDRTYGRELRGE
                     TDDPDYWTAQEEYLRACVVRTAPVRLDSELMSPLTFRTLVGQADYHVTGTLKDWDIFDE
                     LERIRIPTLVLGGEFDECLPSHLADIAARIPDSDHITQPGAAHMGYLEEEPLRSAYVGI
                     VRDHMARIEARDARHSPRSRGA"
     aSDomain        complement(16061..16789)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFP59_RS00525_Abhydrolase_1.1"
                     /evalue="3.50E-23"
                     /label="CFP59_RS00525_Abhydrolase_1.1"
                     /locus_tag="CFP59_RS00525"
                     /protein_end="271"
                     /protein_start="28"
                     /score="74.4"
                     /tool="antismash"
                     /translation="PLLLVHGGPGYPSDVLFEAFEPLAREREIVWYDQLGVGRSDPIDD
                     PLLLTVDRFLDELGAVTEGLGLDRAHVYGHSWGAMLGLQFAARRGPEWTSLVCANGPAS
                     VPRFMEEVRELLAGLPGNVLDRTYGRELRGETDDPDYWTAQEEYLRACVVRTAPVRLDS
                     ELMSPLTFRTLVGQADYHVTGTLKDWDIFDELERIRIPTLVLGGEFDECLPSHLADIAA
                     RIPDSDHITQPGAAHMGYLEE"
     misc_feature    16864..16878
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            complement(17133..18137)
                     /locus_tag="CFP59_RS00530"
                     /old_locus_tag="CFP59_00101"
     CDS             complement(17133..18137)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1015: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /locus_tag="CFP59_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CFP59_00101"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_159398793.1"
                     /transl_table=11
                     /translation="MQVLLDASRCAPTDRAAAMSDYLMAASGIPHRVRVLADQPTSAQA
                     RVSGVELDRDVFFAEAIGAGFGIERTKADLRGAGPERIYLQLFDGDRPGHYEHDDVSRP
                     LRRGDLCVTDLNAAFAYHASAAYRTVCVQVDRSRLEMNLETIRRADHRLARSPLYGVVR
                     DHLASLSANALLLTDPGDRESATEATVALLKGLVASAARDDDAASRNAVHDHLLDRIRH
                     FLRMHAGDQGLGPDDIAAAHAISVRKLFQLWQSQPLSLSESIMQLRLEAAQQRLITRPD
                     LTIAAVARASGFVDASHFSRRFRLALGCTPTAWRAEHHDHSPGMNADAPRRAE"
     gene            complement(18257..18379)
                     /locus_tag="CFP59_RS51745"
     CDS             complement(18257..18379)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS51745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269462886.1"
                     /transl_table=11
                     /translation="MIDEHADTACERQFDDLLSLIGHLFGRADLRRWRVRGVTG"
     misc_feature    18336..18351
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            18520..18828
                     /locus_tag="CFP59_RS52110"
                     /old_locus_tag="CFP59_00102"
     CDS             18520..18828
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS52110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CFP59_00102"
                     /product="hypothetical protein"
                     /protein_id="WP_331717364.1"
                     /transl_table=11
                     /translation="MSKRSKPPTPLPQWAMPEESWLYFPTIYEGGKQTVKRAAVAARGG
                     LRGAHGTVPGARIRRARTTVRPADLLAAVMMPVCSRRTFVAQAEDSGHTVSYRVPAP"
     gene            complement(18807..19358)
                     /locus_tag="CFP59_RS50435"
                     /old_locus_tag="CFP59_00103"
     CDS             complement(18807..19358)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS50435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CFP59_00103"
                     /product="hypothetical protein"
                     /protein_id="WP_231981073.1"
                     /transl_table=11
                     /translation="MQARGLGRGTVAVSSLPLLGAAQVVSAGGDQGAPALPDGVFLVKP
                     LNGASIGLGQVAHSGSDVNVVGEVAVRGCLAQAVDGGCQVVLCTAYAVDLARVALRAAM
                     EQARRNGGGRKAKQKPRQVRTVRRDGREPLDLAAAIGALVSSGPGNSRPLAPRCASGGP
                     PPPHELAGHLEAVGYGAGTR"
     gene            complement(19457..19585)
                     /locus_tag="CFP59_RS51750"
     CDS             complement(19457..19585)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS51750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269462887.1"
                     /transl_table=11
                     /translation="MDSLADAIGAPCARSITQRLDTIERVLIALARVQGIDPDTVS"
     gene            complement(19725..20000)
                     /locus_tag="CFP59_RS00550"
                     /old_locus_tag="CFP59_00105"
     CDS             complement(19725..20000)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CFP59_00105"
                     /product="hypothetical protein"
                     /protein_id="WP_100804514.1"
                     /transl_table=11
                     /translation="MAAEDPIAQNELDALTRRVEAVEDRVEALQVQSGGNFAAVIEGQA
                     ALRREVRDGFTKVNARFDAVEAKMDRNQAQIVELLSALVGKSPDEH"
     gene            complement(20214..20363)
                     /locus_tag="CFP59_RS48665"
                     /old_locus_tag="CFP59_00106"
     CDS             complement(20214..20363)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CFP59_RS48665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CFP59_00106"
                     /product="hypothetical protein"
                     /protein_id="WP_159398794.1"
                     /transl_table=11
                     /translation="MAQLRKDNSPDDATDSVRFEHGSEYRWDPSFLEGLRRVLAPIHEE
                     RLQF"
ORIGIN
        1 agacagtggt tgacgtcggc cggcacaccg ctcatcgagg acaggccccg gccctcttcc
       61 atgagcggtg gccggcaccc gtaccaccgc cccgatcgcg gcggtgccga ccatcggcgg
      121 taccggccga tcggggcggc gcggcacccc ggccacgctc gccctcgcgc cggatcactg
      181 cgcgcgtact catccccgta cctccccgca cggcgacgtg tccggcgagc tgagcgcttt
      241 gtccagcacc gcgaagcccg ccctgcggtc gtcgtcggac gagcccgtaa cggccagcgc
      301 gtcatcgtgg gcacgcccct gtacatggcc cctgagcagg cccgcggttt cccggagccg
      361 cgcagcgacc tgtacgcgct cggatggctg ctcttcgagc tgatcacggg gcggctgccg
      421 tttcaggccc ccgacaccgt gggctgcctc tcggcccacc tcacccagga accgcccacg
      481 cccagctcgc tgtccccgga catcccaccc gcctgggaaa gatcactctg ctccaaccgg
      541 gttgatcatg gtgaatatgg cgataggcat cgtggaactg gtggtgctcg ccacgggcgc
      601 gctgctgctg ttccagcaca tgaccggtcg ccggatgatc gcgacaaccg gtggcgtggc
      661 ggcgccgcac gatctgagcg ccagcgtcca gtaaaggtgg tgagtgggcc accggacgtc
      721 gagctgatcg cctacgtcgt cggcccgctg acggccgctt cggcgatcac cgccgtggtc
      781 atggccgcgc tcccgtccgc aggacactgg tgccgtcgcg cggcagggca cggtggtgtc
      841 agcgggcggt cgggacatag gtgaggccga ggacgccgtt ggtgagccgc ttgacgtcga
      901 tcaggtcgaa gtccgtggtg tcgatcccgt cgtagagccg ttcgccgctg ccggcgatga
      961 ccgggaacag ccagaacaga tactcgtcga ccagcccgtg ctcgagcagt gtccggctga
     1021 acgagccgcc ggtgccgacc ttgaggatgt cgccgcccgg ctgttccttc agcttgcgta
     1081 cggcgtcgac gacgtcgtcc ccgagcagcg tggcgttcca cttcacctcg gtgagggtgc
     1141 gcgacgccac gtgcttgggg atggtgttca tccggaccgc gtagtcgccg aacgcctcct
     1201 ccatggtcgg ccacacctcg gcgtggttct cgtaactgac ccgcccgtag aggagcgcgt
     1261 cgacggagaa gagcaggtcc ctggacagct gctcgaactc gccggcccac cgcgtgggga
     1321 gccagtcctg gggcgtgctg atctggccgt ccagggtgat taccgcctgc tcgatgatct
     1381 tccgcacggt cattgctcct tgccggtcgt tgtcgcgtgg tcgacgtgtc gtcgcgtggt
     1441 cgacgtgtcg agagtgcaga ccggtcggag cgagagaact catcggtccg gcgacgccgt
     1501 tggcaaccgt ggcggcggtc cgccggggcg cccgccttcc ctccggctgc ccctggtgtc
     1561 gctccctgcc aaacggcgat cttcgcgaga tgctgctgag cctggcccgc cccgccgggc
     1621 cagcagtccc ttacgaggag cccccatggc agcgtcgcca tccaccgcca ccccgaccga
     1681 tgacgcgtac cgcttcgacg acctgaccgc cctgtacgtc aactgcaccc tcaaaccgtc
     1741 tccgcagcag agcaacaccc aggggctgat cgacagaagt cgcgcaatca tggacgcgca
     1801 cggggtcacc acggacgagt tccgggccat cgaccacgac atcgcgacgg gcatctaccc
     1861 ggacatgacc gaacacgggt tcgccaccga cgcctggccg acgctctacg agcgggtgat
     1921 ggcggcggac atcctggtgc tggcggggcc gatctggctc ggtgacaaca gctcggtgac
     1981 caagcgggtg atcgaacgtc tctacgcctg ctcgagcctg ctcaacgaca ggggccagta
     2041 cgccttttac ggacgcatcg gcggctgcct gatcacaggc aacgaggacg gtgtgaagca
     2101 ctgcgcgatg aacgtcctct acagcctcca gcacctcggc tacaccatcc cgccccaggc
     2161 cgacgcgggc tggatcggcg cggtgggacc ggggccgtca tatctggacc cgaattcggg
     2221 cggcccggag aacgacttca ccaaccgcaa caccgccttc atgacctgga acctgatgca
     2281 tctgggggcc atgctcaagc gggccgacgg catccccgcc cacggcaacc agcgctccga
     2341 atgggaagcg ggctgccgct tcgactaccc caaccccgac taccgctgag gttgccgagg
     2401 atctctccga gagggccgcc gaccggcccg gcctctcgac gagaatcggt gcctcacgag
     2461 ggcggccggt actcgccgag gatcccctcc gcagtgcggg catcctcggc ctcgatcttc
     2521 agcgcttcgt cgatcacccg tcgcaggctt ccgcccggga tcacgaccgc accgctggcg
     2581 tcggcgtaga catagtcccc ggggaccacg catacgccac ccacttccac cgcgacgttg
     2641 acggcatagg gcatggcgat gtcgccgccc caccgagtcg cctctccccg gcaccaggtc
     2701 gcgaagccgt aggcgcccag ttggccgaag tcgcgcagcc gcccgtccgc caggactccg
     2761 gcggcatggg tgtgttcgag cctggagagc ttcgttccac cgccgtggga tacgtcggaa
     2821 tagcctccac tggacagcac cagcacggtg cccgccggac ggtcgcccac cgcctggccg
     2881 aagagatcgc cgaactcggc gtgcgggatg tcgtcgcggt agggcagata ggcaatcgtg
     2941 gcggccggcc cgaacagctt gcgtggcgcg gggctgacga ggccgacgat atgcgcccgg
     3001 tgaccgtgga cccggcccat ggcgtcgacc agcgatgcgc aggacacgcg gtcgggcacg
     3061 ggtttcagat cgctggccac cgtcgcttcc tccctctcac cacaacaccc gacgattccc
     3121 tctataccgg acacatcatg tggcccatgc tagtcacccg tccacaccgt ggcagctcgg
     3181 cgacgaggcg cggaacaccg gggacggcca gcccctcccc ggcaggcaca cgtttttgca
     3241 tggcggtcgc aagactggga gaattgcgaa taacccggac atcagatccg gagggagttc
     3301 cgcatggact cgtccgaagc accgggaatg caattcggca tcttcacggt cggtgacgtc
     3361 acgaccgacc ccacgaccgg gaccgccccc accgaggcgg agcgcatccg ggccaccgtc
     3421 gccatcgcgc gcaaggccga ggaggccgga ctcgacgtct tcgccaccgg cgagcaccac
     3481 aacccgccct tcgtaccctc ctcgccgacg acgctgctcg gctatatcgc cgggcagacc
     3541 gagcgcatca tcctgtcgac ctcgaccacg ctgatcacga ccaacgaccc ggtcaagatt
     3601 gccgaggact tcagcgtgct ccagcacctg tccggcggtc gtacggacgt catgctggga
     3661 cgaggaaaca ccgggcccgt ctatccgtgg ttcgggcagg acatccgcca agccgtcccc
     3721 ctgaccgtcg agcactacgg tctgctgcgc cgcctgtggc gcgaggaggt ggtggactgg
     3781 gagggcaagc tgcgttccgc cctgcagggc ttcactcttg tgccacggcc actggacgac
     3841 atcccgccct tcgtctggca cggctccatc cgcacccccg aagtggcgga gctggcggcc
     3901 tatttcgggg acggattctt cgccaaccac atcttctggc ccacctccca tacgcagtcg
     3961 atggtgcgga tgtaccgccg gcgcttcgcg cactacggtc acggcgcccc ggaacaggcc
     4021 atcgtcggcc tgggtgggca ggtgttcatg cgacgcaaca gccaggaggc ggtcgacgag
     4081 ttccggccgt acttcgacaa tgccccggtc tacggacacg gcccctccct ggaggacttc
     4141 acgacgctca cgccgttgac ggtcggctca ccggcccagg tcatcgagcg cacgctgggt
     4201 ttccgcgact acaccggcga ctaccagcgc cagctcttcc tcgtcgacca cgccggtctc
     4261 cccctcaaaa cggtgctcga acagctcgat ctgctcggtg aggaagtggt gccggtgctc
     4321 cgcaaggagt tcgccgtcgg caggccggcc gacgtcccgc cggccccgac gcacgagtcc
     4381 ctgctccgcg cccgtaggag cgaggaaaag ccgccgtccg acgaggaaga gggaccggaa
     4441 gcacgatgaa attggcgatc atcaccggcg gtctgcgcga gccgtcctcg acgcggctcc
     4501 tcgcggaccg gctggcgacg gctgtgacca gggaactcga acaacacggc gaacaggtcg
     4561 aggcgtcatt cgtggaactc cgtcctctgg gccacctcat catggacgcg atgctgacgg
     4621 gtttcaccaa ggacgaactg gaatccgcct tccgcacggt cgccgacgcc gacggcatca
     4681 tcgccgtcac acccgccttc aacgcctcct tcagcgggct gttcaagtcc ttcttcgatg
     4741 tactgccgga acagacgctt tcggacctgc ccgtcctcat cggcgcgacg ggcggaaccg
     4801 agcggcactc gctggtcctc gaacacgcgc tgcgcccgat gctcacctat ctgcacgcga
     4861 tcgtctcccc ccgtgccgtc tacgccgcca ccagcgattt cggctccccg acaggcgccg
     4921 ccctggcgga acgcatcacc gacgccgcgg ccgacttctc ccgtctgctg cgggcctgcg
     4981 gtccacgggt acgtcgcgaa ccggcggacg aagacctcgc ctccatgcag cggctgctcg
     5041 gcgacacgac cggcgtggga cccggccggc cgacggatcc gacatgaaca caaaggccaa
     5101 gggccgggag gctgtcccac tcgacgcctc ccgaccgatg ggtgtgccgt gggtgctgct
     5161 cggggtggcc ggtcagggca ggatctcgac gtacccgtcg gttccgtgca cgcggatccg
     5221 ctgcccgtcc cggatcagcc gggtggcccg ctccactccc acgacggccg gcaagccgta
     5281 ctcccgggcg atcaccgcgc catgggtcat caggccgccc acctccgtca ccaggcccgc
     5341 gattccgacg aacagcggcg accagctcgg gtccgtgaag gcggtgacca ggatgtcgcc
     5401 cgcctcgaga tcggcctccc ccatatcgag gatgacgcgg gcccgtccct cgatggtccc
     5461 ggcggaaacc ggcaggccga tcagggcgcc ggccggcgcg tcgtcgcgcc ggtacgcccc
     5521 ggtgacggcc tcaccatccg aggtgagcac ccggggcggg gtgagcgcgt ggtacgaccg
     5581 gaacgcgtcc ttgcgctgct ggatgagccg gtcatccacc tggtgcgagc gcacgacgtc
     5641 gtggagttcc tggaacgtga ggtagaagat gtcctcctgt tcaggaagca cacctgcctc
     5701 cacgaggcgc tcggcctccg ccagcagggc ccgcttgtag acgaagtagc ggctgatgat
     5761 gccgtacttg gggtactccc ggtacccgat gaaggttctg acccggtcga tcatccgctt
     5821 ggcctcgtcg gctttccggt ctccgtccgg cagggcccgc aagcgtgaca gtacgtcccg
     5881 ttccttctcc cgcgccttct gccgcccttg ctcgaagcgc cgcccggcgg cgcccggctc
     5941 gaagttcctg acgttgtcga gaatcacggg cacgagcgtg gtggggcgct cgcgccaccg
     6001 tggcctcgtg atgtcgatct cgccgacgca gcgcatgccg taccggtcga ggtaggactc
     6061 gatggcgtcg cgcgcttcgg ccccgcccgc gagcttcgcc agctcgtcca ggaaggcgtc
     6121 gtcctcgatg gactcgacgc cccgcaggaa cgccaccacc tccggatgcg ggcggatcac
     6181 atccgcgacg tcgagcagcg ccagtcccat ctccgatgtg acgttgtcgg gggcggacag
     6241 cgtgagcgtg tcggccgcgt tcttctcgcc cagccactcc cgcagcgtgt cgttgagcca
     6301 ccacgtggcc tccatccccg ccatgatcgc ctgcatgctc agcggatccg tgaggacgcg
     6361 cttgtgctcc tcgaaggcct cccgcaggaa gtcgaacagc gccggtccgg tcttcgtccg
     6421 gatatcgcgc tccagggcgg cgatggacgt ccggctgcgc tcgatcagcc cggtgacgat
     6481 ggccggatcg gtctcgatcg gagcggacac gccgcgggcc gggggcccgc cgggacccgc
     6541 gtccgggagt gacgggacga aatcatcgcg ttcgaggacg gtctccagag cgtccctgat
     6601 cagcggatcg cctctgccca cgacgtccag gagggcggcg cggctcgcgg gcgaggccag
     6661 gcgccgggtg gcgtcgacga acagcctccc gccggcctcg tgcatcggcg ccatggccgt
     6721 cagctgccat acggagatcc ccaggggctt catggggtcg gtcatcatct gctgatggcc
     6781 caccgagagg tagacgtgat tctcctggtc gccgctctcg gggatgggga acagtgtcgt
     6841 gatcggccgg ctctggacga tctggaagtc atcgtcgacc aggcaccatt cgatgtcctg
     6901 cgggcggccg aagtgtgctt cgatccgccg cccgagttcc acgagccgca cgacctgcgc
     6961 gtccgtcagc gccggctgct cctgccgccg cgcgtcgatc gccgcttccc gcgtaccgcc
     7021 gtccggcaga gcgtggacgg cacgctgttt ggcggcgatc gtcctggcga cgatttcgcc
     7081 gtgtcgcacc gtgaagacgt ccgggttcac caggccggag accagagcct cgccgagccc
     7141 gaagccggcg tccacggtgg cgaccttacg gttgcccgtg acggggtcgg ccgtgaacag
     7201 gatgccggcc gcatccgggc agaccatccg ctgcacgacc acggccatgt ggaccgtacg
     7261 gtggtcgatg ccgccgcgcc ggcggtagat caccgcccgc tcggtgaaca gcgaggccaa
     7321 gcaccggctg atgtgctgga ggatcgccgt cggccccacg acgttcaggt acgtgtcctg
     7381 ctggccggcg aaggaggccg tcggcagatc ctccgccgtc gcgctggacc ggacggcgta
     7441 ggcggcttgt tcgccgtgcc ggccgagcgc tcgggtgatc gcccccgcga gatcgcccgg
     7501 gatcgcaatc ccttcgatgg tccgacgaat ccgcgcgctg agcgtgcgga tcgcctcccg
     7561 gtcgtccggg ttcacgcgcg ccaactgatc gagctgatcg tcgatcgaag gcacttccgc
     7621 catgatctgc cggaaggcgt ccgtcgtcac gcagaagcca tccggcaccc ggatgccctc
     7681 gatccgcgac agcccgccca ggtgcccgcc cttgcccccg acgaccgcga cctgcgtctc
     7741 ggcaacctcg cggagatcca acacgtaccg ctcactcatc gcgagacctc cggggcagcc
     7801 gtgctcggcc gcaccgcgag ccggtcccac cgctggtccg acgtcatcgc gtcccccata
     7861 cgccgacaac aacacacgta cgtcgtgccc ccatttccgc aggttgtggc atcggtcgac
     7921 gattgtgcgc catgccccgg ggcttgcggc aagccccccg gcgcgctata tgttgaaagt
     7981 ggcaaggaga gagtgtttct ccttgccttt gcctttgccg tccatgggaa ccgaccagct
     8041 tctccgcgaa gcggcgacgc accgcgtaga cggtcgccgt agctcggatc ggtcggcacc
     8101 cagcgttcct cggcacggtg tccccacaga cacgagcacc atggccgccg agcactcccg
     8161 cggccacggg gaagcgatgg tcctgcacgg ctccgacgaa ctggccgtcc acgggaccgc
     8221 gaagcgtcgg tcgtcgtcct cgcatacgcg gtccgcggtc aagcggtcag caccgcgccc
     8281 gcctacgaca accacttcgt ctccatcgtc gcgatcaagg accgagagat cacgcactgg
     8341 cgcgactgcc gcaaccgggt cgccgtgttc gacgccatcg gccggccgac tccccagcga
     8401 gtgaacgtcg gagggtgcgg cgagcgcgac cgcgatcacg gcggcgtacg gccgtccgcc
     8461 cgtccccggc acgccgccat gagcggcctg ccgggtgccc atgcgcggtg ctgaaccgat
     8521 gcctgcacgg ttcagcgatg ggctgggaga gccgggtgcg gtacgcggcc gggcaggcga
     8581 gaaacgacct cgggtcaggc gccgtgctcg tccggccgga cggcgtcgtc gcctgggcag
     8641 gtgagcgcca cccggaccgt gaggcgttcg agcgggccgc ggtccagtgg tacggcagcc
     8701 ccggtgcttc aggtagctcc cccgtcccct tcgcgcgcgc cgtcgaaggt ggcgtgcgcg
     8761 gatcacgggg agacggtggc agcaggcggg gtccatcggt gggtgcgggg caccgtgccg
     8821 gggatgccgt agtccttcct gagctgctcg gggatggcgt agtgcatcac gcgtccgcgg
     8881 gtgagggagg acagttcgag gatggtggtg aggtggccga ggcggtccag cgcccaggcc
     8941 ccgagcgggg agcggtcctc gatggtctcc agtacaccga gaaggtgggg cacggccttg
     9001 acgacggcgt cccagggggt gcgcgacacc tggagccagt cggcgcaggt gtcgccgaca
     9061 aggtggcgga tgagggcgga gacgatcggg tcgaagaagg tcccgggcac gacctcctcg
     9121 tagaggtcga tgagctgccg ggtcagatgc gcgccttcct ccgtcggccc catgtgccgg
     9181 accatgtaca ggtcgaggaa ccggcgggcg tcgtcgagag tcgtggggac gacgtcctgg
     9241 tcgacgccga gcatggctcc gaccacgcgc caggcgtagt aatacgcctc cgcgccctcc
     9301 gtcgacatgt ggatgccgag gcggtgcagg ctgtccagga ccagcaggga gaagaacatc
     9361 tgcccgccga tcatgtcctc ctggcagatc ggcgtcccga gcgcgtcggc gtcccagcgg
     9421 ttctcccgcc tcaggtggtg gcggatggag gcgtgcagca ggcggacctt ctgggcggcg
     9481 gggatgaagc ggctgccggc ctcgaaggcg ccgggctgca tcagatagac ggtgaactgg
     9541 ccggtctccg ccatgcgttt ggaggggtac ttcagcccgt gggtggccga cagcagcttt
     9601 gccacccgcg ggacgaggta gcacgcgggc atggaggcga aggacagcgc ggtggagatg
     9661 tgcacgttgt tgtcgatgaa gaacagccgg gccttctcca tctcccccca gtccacccag
     9721 gccggcgggg cgctggtggc ccgaaggtac tcgcgggcga catcgggcag cccgtccggc
     9781 aagggagcgc cgacggtgga gacatagcgc atcagggtgt tgaacttccc cacctccccg
     9841 cgctcgaaga gggtggcgac ggtggcgtcg gcgagttcgt caccggcctg ccgcagggcg
     9901 tccatcgatg cctcggtgta ggtcatgacg ggactccttg tcattgacgg gtcgtccacg
     9961 acacaggcgg gggcggcggc cgtcccgcct gtgcgggggg tcaggacagg cggaccgccg
    10021 ccgaacgcgc cagcgcggtc agggcagcgg cggcgtacgg gggtgtgtcc agctcgtgca
    10081 gggcgtcgag ggcctcctcg acccgcgcgg tgatcatggc ctcgatacga tccggggcct
    10141 tcagccggga catcacctcg cggaccgcgt ccagaccctc cgcatccaga tcgcgtcggc
    10201 cgaggagggc gctcagccgc tcccgctcac cgtcaccggc gatgcgccag gtctccgcca
    10261 gcagagccgt gggccggtgg ccgcgcacat cgtcggcgtt ttccttgccg gtgcgttccg
    10321 ggtctccgaa caggccgagc aggtcgtccc ggagctggaa cgcctcgccc agcggcaacc
    10381 cgtacgcgga gtagccctcg cgcagccgcc ggccggcccc ggccagggcg ccaccgatca
    10441 acaggggctg ctcgacggtg tacttggcgg tcttgtaccg gatcaccttc agcgacgccg
    10501 tggtgtccgg atcggccccg gtccgcagga tctccaggca ctcccccgcg atcagctccc
    10561 gggccagcac cgaccacagc gggcgggccc gtgccaggta cgcggcgggc agaccgctgg
    10621 tggcgaacat ctgcccggcc agcgacatca gcaggtcgcc caccagcatc gccagcgacc
    10681 tggcggcggc gacggcacgc ggccgacggc gtacggcggc gcgcagggcg atatgcgccg
    10741 tgggccggcc atgccgcagc ggactgtcgt cgatgagatc gtcatgcacc accgcggcgg
    10801 catgcaccag ctccatcgag gccgccgccc gcacaagcgc atcgctgtcc gactgcccca
    10861 ccgcgcgcca gccccagtag cagaacgccg cccgcagccg cttgccgtcg gcgactgccg
    10921 cctccaactg cccggccacg gggcccaggg ccgggtcgat cgccgataac tgctcggcct
    10981 cctgggcgac gaagccgtgc agcacctcgt cgacgcgggt cttgaacgcg accggcctcc
    11041 agcggtcgga cccccaccga tcaggccccc accgatcgga cccccgccgg tcagacatcg
    11101 ccggcggccc gccgggccag cgcgtgccgg gcgagaatct ccaggtgggc cggggggacg
    11161 gccgcggtat gccgttccag cgccaggcgc ccgcgtgcca tcagatcgtg ctcggcctcc
    11221 gccgccagct ccgcggcatc cgagcggcgc agcaaccccc gcgccgcccc cagcaccgaa
    11281 cccagcgtgc tcaccgccag atcggccagc ccggccgcca gcagcacagc ccgctcgtcc
    11341 agtcccccgc gtcgtcccgt gccttgcgcc atcccatccc ctaccctcag ccgccggtca
    11401 cacgccgtgc tggccagcgt ggcatcacac cgggcatatg aagggaacaa ctcacgatcg
    11461 agtgacggca tcgctcgtgc gtacggactg ctccttccgt caggggccgg gcgatcacgg
    11521 cccggcgcac ccccctagcc gcgggggctg ctgatccgtt ccggctggat cacatagagc
    11581 acccggactt gatcgcggcc accgaaccat gggtaggacc caccgaggta cttctgcgcg
    11641 agcgcctcga tgtgttcggc cgctccctcg gtggtcaccc gcaccacacg gccgcggatc
    11701 cggacgtagg aggcgggttg cgcggcgggg gccaccgccc agcagggaga acaccccggg
    11761 agcccgatgc cctcacgctg gtccctcaga tgcagcaggt agcgaccctg gccgtcatgg
    11821 atcaaggcgg acgcattcac cggctgaggc tgtccatcga ggccctgggc cttcgcggcc
    11881 agcagcttgg cccgcagcgt cggcgaccgg acgtcggaga atccgagcca tcgagcaccc
    11941 gagacttcct cgtcctgcag ctccagcacc ggcgcacgat cgggcatgag gtagaagacg
    12001 taccggaagt cgtagtgctg gtgcgccggc tcgcccttgg ccggattggc gtcaatatcg
    12061 tggacgtcga tgtcgagcgc cttgcccagg agctgcggag tgagacacag atcgtccggg
    12121 cggagtccgg tttcctcaca cacctcccgc agcgcggcgg ccaggagagt ccggtcgttc
    12181 tcgacgtaac ctccgcccgg tgtgaggagc ttgcctgacg ccttgtgcac gatgtgcagc
    12241 acgcgctgct cgcggtcgat gacggtggca ctgcaggtga tgtgggcggg cagcgtcgcg
    12301 cggctcgtcg gctcgtccgg ccgctcgagg gcggccagca gcccggccag ggcctcctgc
    12361 cgtgcggatg ccgggccagg tagttctcag cggtcgcgag gatgtgggag cgggcaggcg
    12421 gcacgtcatc acctcgaagg agcgtggagc ggtcagaagg atcgggggat gctggacgag
    12481 gcgacgggac caggcgcagt ggtgtcggag cggctcatga gcggctcccc tgctgctcgc
    12541 tgtccgccgc tgaggtgacc tggtaggaca gcaattgctt aagacatcat ctcatttggt
    12601 aagtctgcgg tagcagatga gagtacaggc gatgctggtg aaggccagga agtggacagc
    12661 tttccgttcg taacgacggt ggagtcgtcg gcatcccgcg agccaggaca tcgtgcgttc
    12721 gatggtccag cggtggcgtc ccagccgctt ggaggactcg atgcctttgc gggcgatgcg
    12781 ttaggtctgt ctgtcggccg tggggccttg acccggaatc ttggacacgg gctatgcggc
    12841 ttgggccagg gtagttgatg ttgtgtcgag tgctgtctcg taggcgatgg gactgcgttg
    12901 tccgaggcgg gagtgacggc gtcgggtgtt gtagcggttg agccagccga acgcgtcgag
    12961 gcgggcatcg cgctcgctgg accaggtctt gcggccctgg agcgtctcgc gtttgaacgt
    13021 cgcgttaaag gactcggcga gtgcgttgtc cgcgctggag ccgatcgcgc tcatggactg
    13081 gcggacgccg gcctggcggc aggcgtcggc gaaggcccgg ctggtgtact gggctccgtg
    13141 gtcggtgtgc atgaccgctc cggcgaggct gccgcgggtc cgttcggcgg cggccagggc
    13201 gtcggtgacg aggtcggtgc gcatgtggtc cgcgatcgcc cagccggcca ggcggcgcga
    13261 ggcgaggtcg atgacggtgg ccacatacaa aaacttcccg ccctccagcg gcagataggt
    13321 gatgtcgccg acgtacttcg tgttcggctc gcttgcggtg aagtcgcggc cgatcaggtc
    13381 cggggccttc gccgcggccg ggtccgcaac agtggtgcgg tgccggcgcc gcagccgcac
    13441 gcctgccagg ccgatgctcc gcatcacccg cgcgatccgc ttgtggttga ctcgctcgcc
    13501 gtcgtcgcgg agttcggcgg tgatcctggg gacgccgtag gtgccgcctg attcgtggtg
    13561 cacggcccgt atccgggtgg cgaggcgggc atcggccgcc tgccgggcgg cccggtccgc
    13621 ggccgtccgg cgccagtagt agaagctgga gcgggcgatg cccaggatgg tgcacagccg
    13681 cttcacgccg tagcggcgct ggtggtcggc aacgaactgg aagcggttca ccagcgcgtc
    13741 tccccggcga aatacttcgc cgccttgcgc aggatctcgc gttcctcctc cagctcgcgg
    13801 accttcttgc gcagagcggc gttttccgcc tccagcggtg tcggctgctc ggcgggtgcc
    13861 tctgcccggc gtccccgcgg ccggctcgcg ccggctgccc ggacccagtt ccgcaaggtc
    13921 tcggggttga ttcccagatc ggcagccacc tgccggatcg tcgccccggg ccgcgactga
    13981 tacagcgcga ccgcgtccgc cttgaactgc ggcggatagt tcttcatgac cacgagatgt
    14041 ccgttctcag atcctcagga tccagtgtct cgtgtgtcca agatcaaggg tcaaggcccc
    14101 ctcgccaagt aaccccctcc cgcatcacgc agtggcccgc cggcacttgc ccgccgccgg
    14161 gcctctgccg tgtgtcgacg cgacggtacg gtccaccgcg tggcagtgcg ttctcgcctt
    14221 cacctcggca ctcgcgcgac gcgacggacc ccgcagacca ccatcgaaga gaggcggagg
    14281 cgtcacgcct ccgatctcct ccaccgtcgc ctgagccctc gctccgtcac ggccggagac
    14341 gacaaacgaa atcgctgcgg tcggcggatc ggcggggacc gcacggcgcg ggagccaggg
    14401 cccctgggca cggaccgcgt tgactgacgc gtcagatacg gctgaaccct gcccacttct
    14461 tgatcacgaa gtggctcccg ttgcgggcga tttcgacggc gccgtgaccg ggcaagtgct
    14521 ccggcagcaa gagcaccttg cggtcggcgg tccactccag cgtgcgccgc cgggtcatgc
    14581 gcgcctgctt ctcgtcttcc tcgaagcaac tgtcgaactc ggggtgttcg agctgcaacg
    14641 gcgtgtgcag cagatcgccg gcgaacaccg ctctgtcgcc tcccgactgc agccggacca
    14701 cggaggagcc gggggtgtga ccgggggcga ggtccagcgt cagattgccg tcgatggtgt
    14761 ggctgccgtc ccacagcttc accagaccgg cttggtgcac gggcaggatg ctgtcttccc
    14821 acacgttcag ggcggccttc ggatccttgg ccttgctccg gtgctccgga gtccagaatg
    14881 tgaactcggt ctcggggatc aggtaagtgg cgttcgggaa ggtggggacc cagtcccggc
    14941 cctcgcgtcg ggtgttccag ccgacgtgat cgttgtgcag atgggtgttc acgacgatgt
    15001 cgacgtcctg cgggcgcacc ccggctcggg acaggcgacg caggaagccg gcgtccaggt
    15061 actgccacgt cttcgcgtac ggccggaact tgtcgtttcc ggcacctgtg tcgatcagga
    15121 tcgtcctgcc ttcgctgcgc agcacccacg tctgcagcgc gatgcggacg gcgtccgtgt
    15181 tagggttcca gaagtccgga ctgagccagg agcgattctg ccgccacagt ttctccgggc
    15241 tgtccgggaa gaactcacgc gacgtcattc ccaccgggcc cgtgtactcc actacgcggc
    15301 tgatggtgac attgccgagc gtgatcgtgg acgcctgcat cgcctgctcg gaggtggccg
    15361 cgggtgtgcc atgggtgccg ctggtgagcg cccgaccacc atcgagcagc gcggccgccc
    15421 cgaaccctgc gctgatgccc gctgcggctc ctatgaatcc gcgccggttc atggggcgta
    15481 gaggctggtc actgtgcatc gctcggctcc tgtcacagaa gagggtgggg gtcaccagcg
    15541 gaatggtcgc ttcgtgctca gcgtggcaaa gagcgcggca gttcaggtgt gctgacaatg
    15601 cagacccctc gccccagggc gcatgactgc ggacaacttc cctcaccccg caccgcggca
    15661 tggcacaagg agtcctcggc ctcgggctcc tgccagtacg tcgcgccgtc cgcgctgtcg
    15721 ccaagcgcgc ccatcagccc ccattcgccc gcgtccgcgg ccacgcgggc ggggtcgagg
    15781 ccgtccggtc gccgggagca acgcccgcgt cctcgccgcg tcggtgcgcg cgtacgccgc
    15841 gtggaaaagg gacttcccct accgcgccgc tgcctgccgc caaggccacg cacaagcgac
    15901 gtccccgtgg ccgagaagca acgcgccgcc ctcggaatga acattcgctc aggccagggg
    15961 ctcacgcccc gcgagagcgt ggggaatgac gggcatcacg ggcctcgatc cgcgccatgt
    16021 ggtcccggac gatgccgacg taagcgctgc ggagcggttc ttcttccaga tatcccatgt
    16081 gggccgctcc gggctgcgtg atgtgatcgg agtccggaat acgtgcggcg atgtcggcga
    16141 gatgcgaggg aaggcattca tcgaattccc cgccgaggac gagcgtcgga atcctgattc
    16201 tttcgagttc gtcgaatata tcccagtcct tgagggtgcc ggtcacgtgg tagtccgcct
    16261 gcccgacgag cgtccggaaa gtgagtgggc tcatcagttc cgaatcgagc cggaccggag
    16321 cagtgcgcac cacgcaagcg cgcagatatt cctcttgcgc tgtccagtag tcggggtcgt
    16381 ccgtctcacc ccgcagttcg cggccgtaag tacggtcgag cacatttccc gggagtccag
    16441 cgagcagttc gcgaacctct tccatgaacc ggggcacgct cgccggtccg ttggcacaga
    16501 ccagactggt ccactccggc cctcgccgcg cggcgaactg gaggccgagc atggctcccc
    16561 aggagtggcc gtagacatgc gccctgtcca ggccgagccc ctcggtcacc gctccgagtt
    16621 cgtcgaggaa gcggtccacg gtcagcaaca gggggtcgtc gatcgggtca gaacgcccca
    16681 ccccgagctg gtcgtaccaa acgatctcgc gctcccgggc gagcggctcg aacgcctcaa
    16741 agagcacatc gctgggatat ccaggaccac cgtgcaccag aagcaacggc acaccgccac
    16801 gtcccattct gcggtaccaa acattccctc cgggcaccgg gatccggcct tccgtgatac
    16861 ggatggagtt cacttccaac ctcctgcgac ggtgcgccaa ctgctgacca taatgatgga
    16921 ggcgcccgaa atcattgcac cctcaacgta gcgaagaatg cgccaagaag taagtcttga
    16981 cttgcctcac ggattccggc agtacaattc ggcttccgag cccccaactg tgcgggggcg
    17041 caggtccgcg tccgcgtgcc tgatggcgtc acctgcggta tctcggccgg ccccgcatgg
    17101 ctggcagagg gggcgtccgg tcgcggtggc ggctactccg cgcgcctggg ggcgtccgcg
    17161 ttcatacccg gagagtgatc gtgatgttcc gcgcgccagg cggtcggggt gcagcccaaa
    17221 gcgagacgaa agcggcgaga gaagtgcgaa gcgtcaacga aaccgctggc acgggcgacg
    17281 gcggcgatgg tgaggtccgg tcgcgtaatc aggcgttgct gagcggcctc caggcgcaat
    17341 tgcataattg attcactgag ggagagcggc tgggactgcc agagctggaa cagcttgcgc
    17401 accgagatgg cgtgggcagc agcgatatcg tcagggccga ggccctggtc accggcgtgc
    17461 atgcggagaa agtgtctgat ccggtccaag agatggtcat gaacggcgtt acgggacgcg
    17521 gcatcgtcat cccgggcagc gctggccacc aaccccttca gcagagcgac ggtcgcctcc
    17581 gtggcggact cacggtcccc gggatcggtc agcagcagag cattggcgga cagggaggcc
    17641 aggtggtcgc ggaccactcc gtacagaggg ctgcgcgcca gccggtggtc ggccctgcgg
    17701 atggtctcca gattcatctc caggcgggaa cgatcgacct ggacgcaaac tgttctgtag
    17761 gcggcagagg cgtgataggc gaaggcggca ttcaaatccg tgacgcagag atcgccgcga
    17821 cgcaacgggc ggctgacgtc gtcgtgttcg tagtggccgg gcctgtcgcc gtcgaacagc
    17881 tggaggtaga tccgctctgg accggcccct cgcagatctg ctttggtgcg ctcgatcccg
    17941 aagccggcgc cgatcgcctc cgcgaagaag acatcgcggt ccagttccac cccggacacg
    18001 cgggcttggg cggatgtggg ctggtcggcg agcacacgga ctcgatgggg tatgcccgat
    18061 gcggccatca gatagtccga catggccgca gcgcgatccg tcggtgcgca ccgcgaggcg
    18121 tcgagcagta cctgcatgtg tccgcctccg ctccgaacag cagccgccgg ccaccgctta
    18181 cccgctccca taagcagaac cagcagttta caggggtttg tgcagcgcgc gccgacaagg
    18241 tggcgccacg agttcgtcag ccggtcacgc cacgcacccg ccaccgccgc agatcggcac
    18301 ggccgaagag gtggccgatg agggagagga ggtcgtcgaa ctgccgttcg caggccgtgt
    18361 ccgcatgttc atcgatcacg gtgcgaggat gtccgcctcg ctgccagccg accacctgga
    18421 gcacaacctc tgactgagca gctcccgggg catactgcct accgaccggg ccagccttgc
    18481 ggcgggcgga gccgaagacg agcgaggggg acgatgacca tgtcgaagcg gtcgaagccg
    18541 cccacaccct tgccgcagtg ggcgatgcca gaggagtcct ggctgtactt cccgaccatc
    18601 tacgagggcg gcaagcagac cgtgaagcgc gcggcggtag ccgcccgagg cggtctccgg
    18661 ggtgcgcacg gcaccgtgcc gggcgcgagg atccgcaggg cgcggacgac cgtgcggcct
    18721 gccgacttgt tggcggccgt gatgatgccg gtctgctcca ggcggacttt cgtcgcccag
    18781 gccgaggact ccgggcacac ggtgagttac cgggttccgg cgccgtagcc gacggcctcg
    18841 aggtgcccgg ccagttcgtg gggcggtggc ggcccaccgc tcgcgcagcg aggcgccagc
    18901 ggccgggagt tcccaggccc gctgctgacc agcgcgccga tcgccgccgc caggtccagc
    18961 ggctcgcgcc cgtcccggcg caccgtacga acctggcgcg gcttctgctt cgccttccgg
    19021 ccgccgccgt tcctgcgggc ctgctccatc gcggcccgca gcgcgacccg ggccaggtcc
    19081 acggcgtacg cggtgcacag gacgacctgg catccaccat cgaccgcctg cgcgaggcaa
    19141 ccgcgaacgg cgacttcgcc cactacgttg acatcgctac cggaatgggc gacctgcccc
    19201 agcccgatgg aagcaccatt cagtggcttg acgaggaaca caccgtccgg gagcgctggc
    19261 gcgccctggt caccgcccgc cgagaccacc tgcgcggcgc ccagtagcgg cagagaagat
    19321 acggcgaccg tgccgcgccc cagccctctg gcctgcacac atacggctgt ggccccgaac
    19381 acgttaggtg ttcggggcca cagccgttca agcgtgagag ttcagccagc gttggggtcc
    19441 cagccgacca gctgggtcag gagacggtgt cggggtcgat gccctgcaca cgggcgaggg
    19501 cgatcaggac tcgttctatc gtgtccagac gctgggtgat cgaccgcgcg cacggcgcac
    19561 cgatggcgtc ggcgagggaa tccacgttcc cgaacgccgt acgctgctgc tcgcggatcg
    19621 tcgccagctg ctcgctgtgc ccaaccgtcc gcccggtgcg gatcccctca gatccgggcc
    19681 cttcgtgtct tgaagagggg tcgtaccggc cgccactgtg atgatcagtg ctcgtccggg
    19741 ctcttgccca ccagagcact caggagctcg acgatctgcg cctggttgcg gtccatcttc
    19801 gcctccacag cgtcgaaacg agcattgacc ttggtgaagc cgtcgcggac ctcgcgacgg
    19861 agcgcggcct gcccctcgat cacggccgcg aagttaccgc ccgactgcac ctgcagagct
    19921 tcgacgcggt cttcgaccgc ttcgacacga cgggtcagcg catcgagctc gttctgagcg
    19981 atggggtcct cggcggccac gcgggccctc ctgccagatc atgatcatgg aaatcagcgg
    20041 tcatcaggcg cttcatgata tcgcgccagc gacaagcagt actcccctat tcggcccagc
    20101 tttcatcagc gcccaccgct gccgttttcg acgtgcagcc gacggcgccc gcaggcgagt
    20161 ccggccggcc ccggaggaga gccgccgccc ctcgcacggc ttcacggagg ctgtcagaac
    20221 tgcagccgct cttcgtggat cggcgcgagg acacgtcgca gcccctcgag gaagctgggg
    20281 tcccagcggt attccgagcc gtgctcgaag cgcacggagt cggtggcatc gtcgggcgag
    20341 ttgtccttgc gcagctgcgc catcggacgg cgacagggtc gcccgagtcc tccaggtcgt
    20401 ggccgagggc gcgcagccgg atctcccagc gaggctggat actcccggcg ggttcaccag
    20461 gctcgcgttc gatgagggcg atgaggacac ggacctgggc gcggtggacc tcggtggggg
    20521 ccgtgccctg ttcacgggcg atgagataga gggcggtcgc aagcgccgcg ccgccgtcgg
    20581 cgagaaccac cccgtcccag gacagtgtcg tggtcggcca gctgcgcccg caacaggcag
    20641 agaacagtca acaccgacgc tgccccactg ccctcggcgc cgagacggcc ctgacactca
    20701 cgggatgggc cgctgtgcca gcccttgccc acctgcggtt tctcggggct gccacggtcg
    20761 tatgcagggg ctacccaaca gcgatcgttg gtgtgctctc gattgttggc ggcgcaaccg
    20821 aacggaaagc ttgtctcacc ggcgcgattg ggcgccgggc ggattaggga cgagcccatg
    20881 attttgcgag gacctccgag ggcggctgcg gccttccccc agcaatgggt atgtgctcag
    20941 tccgccgtct cagctgcggt gccatcgtcg gcgatccggt ccagccattc gcccagcaga
    21001 atgcgttcac cgggggtgag gtgccgcacg ccgtcgccga gcagggcttt gagcgcgatg
    21061 gcgtggacag ccgccttgcc tgccaggtcg ccagctcg
//
