LOCUS       NZ_PIJH01000004        26413 bp    DNA     linear   CON 19-FEB-2024
DEFINITION  Geobacillus thermodenitrificans strain JSC_T9a scaffold_3, whole
            genome shotgun sequence.
ACCESSION   NZ_PIJH01000004
VERSION     NZ_PIJH01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Geobacillus thermodenitrificans
  ORGANISM  Geobacillus thermodenitrificans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus.
REFERENCE   1  (bases 1 to 206033)
  AUTHORS   Carlson,C., Singh,N.K., Bibra,M., Sani,R.K. and Venkateswaran,K.
  TITLE     Pervasiveness of UVC254-resistant Geobacillus strains in extreme
            environments
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 206033)
  AUTHORS   Singh,N.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-NOV-2017) Biotechnology and Planetary Protection
            Group, Jet Propulsion Laboratory, California Institute of
            Technology, 4800 Oak Grove Dr., Pasadena, CA 91109, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/19/2024 01:04:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,567
            CDSs (total)                      :: 3,480
            Genes (coding)                    :: 3,412
            CDSs (with protein)               :: 3,412
            Genes (RNA)                       :: 87
            rRNAs                             :: 9, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 6, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 32 of 68
            Pseudo Genes (incomplete)         :: 44 of 68
            Pseudo Genes (internal stop)      :: 21 of 68
            Pseudo Genes (multiple problems)  :: 24 of 68
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:59:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 153823
            Orig. end                         :: 180236
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PIJH01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26413
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26413
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26413
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16413](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16413)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(619..753)
                     /locus_tag="CV632_RS18560"
     CDS             complement(619..753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CV632_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269799546.1"
                     /transl_table=11
                     /translation="MTPMLPPPRQFTGLPSGLAKLAFVIAESLRPMAKEMKQRQTAGE"
     gene            1005..1907
                     /locus_tag="CV632_RS11745"
                     /old_locus_tag="CV632_11745"
     CDS             1005..1907
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020756897.1"
                     /locus_tag="CV632_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11745"
                     /product="glycine betaine ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_008881427.1"
                     /transl_table=11
                     /translation="MLRKWFMSLLAVGLVLGLAACSGKSDAKGKIVITGKKFTEQMILT
                     HVLAEYVKANTDLDVEVKESLGGAFMLQQAIENGDIDMYVEYTGTGYLNILKQPYDPTK
                     TPEQIYNETKKLYKEKYNIAWLKSLGFNNTYALAMRRDLAEKLGVKTYSDLVNHSSSLT
                     FGSDAEFFERSDGYDGLVDTYGFHFKKTVNIDPDLQYEAAKNGKIDVITAYTTDARIKK
                     YDLVVLKDDKQYFPPYYAVPIIRQEVLDANPGLEEKLNQLANILTDEKMMELNGEVNLE
                     GKQPRKVAIDFLKSEGLID"
     gene            1924..3057
                     /locus_tag="CV632_RS11750"
                     /old_locus_tag="CV632_11750"
     CDS             1924..3057
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229819.1"
                     /locus_tag="CV632_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11750"
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_008881428.1"
                     /transl_table=11
                     /translation="MIRFENVTKQYEDGFVALKNINLEIRKGELVALIGPSGCGKTTTM
                     RMINRLIEPTSGKVYIDGQDISELDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLK
                     KWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEP
                     FSALDPISREQLQDDIIRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPD
                     QMLRRPANSFVREFIGEDRLQMRTRQTAVPTAEDLMSDDVATISPRRGLAEAFRLMKAR
                     KVDSLVVVDKKHSFLGIVTLKQIEQRYNEEHLLVADIADYDVTTLQKEAGVTDVAALFQ
                     DSDVRIIPVLDGDRLVGGITRSSMMRALAEWTFQQHA"
     misc_feature    3361..3376
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.48"
                     /tool="antismash"
     gene            3447..4076
                     /locus_tag="CV632_RS11755"
                     /old_locus_tag="CV632_11755"
     CDS             3447..4076
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881429.1"
                     /locus_tag="CV632_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11755"
                     /product="ABC transporter permease"
                     /protein_id="WP_008881429.1"
                     /transl_table=11
                     /translation="MELLQTFIERQEEIWIAFQEHVLLSAIAMGIAIAVAVPLGVVLTR
                     YRKLAEPIISIAAIIQTIPSLALLGFMLPIFGIGKLPAIIALTLYALLPILRNTYTGIL
                     GVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGL
                     GDLIDRGLRIADKNLILAGAIPAAILAIVFDWLLRKVEKKVTPKGL"
     misc_feature    complement(4598..4611)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.18"
                     /tool="antismash"
     gene            4729..5418
                     /locus_tag="CV632_RS11760"
                     /old_locus_tag="CV632_11760"
     CDS             4729..5418
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888813.1"
                     /locus_tag="CV632_RS11760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11760"
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_008881431.1"
                     /transl_table=11
                     /translation="MGEYMLETHHVSKAFGKQLVVDDVSIKVKKQTVYGLLGPNGAGKS
                     TLLKMLTGLLRPTKGEIMINGHPWSRKDLKDIGVLIESPALYGNLTAHENLLVHAKLLH
                     LPESRIQEVLNIVGLENTGKKKASQFSLGMKQRLGIAKALLNHPKLLILDEPTNGLDPL
                     GIQDLRKLIQSFTENGITVILSSHILSEVKQLADYIGIIQNGKLRYEGKIDESQDLEKL
                     FVDVVNE"
     misc_feature    5429..5443
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.67"
                     /tool="antismash"
     gene            5437..6183
                     /locus_tag="CV632_RS11765"
                     /old_locus_tag="CV632_11765"
     CDS             5437..6183
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886701.1"
                     /locus_tag="CV632_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11765"
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="WP_008881432.1"
                     /transl_table=11
                     /translation="MLNMFESERLKYKRTFAKKLVFIAPLFFVLYAIITMPTINSTHNY
                     FEYAVFNWWPLIFVPIGTALIASLSTVREKKSGNDKVLRCHDISIVRLWWSKITVIAYY
                     MLLSTIELIILLVLLKWLFPNSLSSATVAVFASLVIWLTSLAYIPIGLFVAERFGMVVS
                     IIVSVIGLALGVVMAAQPYWLFIPWSWGMRMMCPIVGVHPNGVPLEKGSPLLDPSVIPI
                     GLAIALVMFLLLSFLTAVWFARKEVY"
     gene            6185..6973
                     /locus_tag="CV632_RS11770"
                     /old_locus_tag="CV632_11770"
     CDS             6185..6973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888811.1"
                     /locus_tag="CV632_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11770"
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="WP_029761610.1"
                     /transl_table=11
                     /translation="MWFLRLLSSEWIKTKRTAIRMMVIITPIIYSLFMVWYFSHYRTST
                     FWQMKIYQGFFEVMAVSLPIIISLLTGLMSYQEEKAGSFMNILTGPVSKVQWYVGKLTL
                     LIFIACADILLATILMLVGMKYVLKVAHIHYQLFLQGAMLSIVGSLILFSLHLFISFAF
                     GMGASIAVGSGGFLISALIGATSLGDHVWSYIPWAWAVRLSQFPILMMPEVKQALGAQL
                     LNSFSLSLWEGIAYALLSFIIVTIIGSIWFHRWEGNQPHE"
     misc_feature    complement(6194..6203)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.78"
                     /tool="antismash"
     gene            7028..7462
                     /locus_tag="CV632_RS11775"
                     /old_locus_tag="CV632_11775"
     CDS             7028..7462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881434.1"
                     /locus_tag="CV632_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11775"
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="WP_011886699.1"
                     /transl_table=11
                     /translation="MKNSILLLMLIGILFIGGCSLVSDLKKTATQNMEIDRKLPKYELN
                     KENLQEIHYQGRTYMIQAAKVDRNQLNKPIGKVAETITINEHHQILSKKELRKIEVIPD
                     QTDEKRTHLNFGWVYSIKGVNPDEEVAVTVNHQFLIAKRK"
     gene            complement(7556..8974)
                     /locus_tag="CV632_RS11780"
                     /old_locus_tag="CV632_11780"
     CDS             complement(7556..8974)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004888809.1"
                     /locus_tag="CV632_RS11780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11780"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_008881435.1"
                     /transl_table=11
                     /translation="MKKNKTIKRDFYLLVVKVVLATAISSAVTYLCLIYLIITLATNDV
                     VKPTNYFVKDLDLIEKKVKENEEAIFKGRLIPIHRYSEKIQGEVVDISGKHLYGDREII
                     DDQVDISQSINREIVKGSYVYRFIPLKHDNAIQAVYVLKAPFGFIINNQNRFEAVLIYA
                     VMFISPLIFFIVYLIFFTSRLYKSLFHNVKLLLQASDHIASGNFDFQVSGLKRKEFIKI
                     QDSFNTMISALKEMVERLAKTDDERKMMVSSIAHDIRTPLTVIQGQIDLIQDLRKLDHF
                     DVTPHLEIIRKNCGKMTMLTDNLSLLYKVENDHFSLNGKEVDVRQILEEKKLEISTMVY
                     HQKSINICFDVNLQKSSYILDEAMLMRVLDNILYNSLRFTKSGEIKLEVHDEKEGNEWK
                     IYFRCSDTGTGFKENDTSLLFQPFYQDKQYKNHVGLGLYIAKRIVNHHGGEIWAYNNEK
                     GGATVEFYIKELSD"
     gene            complement(8961..9659)
                     /locus_tag="CV632_RS11785"
                     /old_locus_tag="CV632_11785"
     CDS             complement(8961..9659)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008881436.1"
                     /locus_tag="CV632_RS11785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11785"
                     /product="response regulator transcription factor"
                     /protein_id="WP_008881436.1"
                     /transl_table=11
                     /translation="MNNKKILVVDDDEDICCTIKQYLELHHYQVETVHSGVEALKMIND
                     DFDLIVLDIMMEGIDGMELCTIIRDRVDYPIVFVSAKTLEEDKVQALAIGGDDYITKPF
                     SLKELKARIDSHLRREERIRSNERYLLSSKNITIDLLANEVFCKGKKLPLTKKEYEIVK
                     LLMLNKKVVFSKERIFERVWGIDSDSQLDTVTESIKNIRKKIKAVDPETSYIQTLYGLG
                     YKWDVTDEKE"
     misc_feature    complement(9781..9794)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.41"
                     /tool="antismash"
     gene            complement(10001..11296)
                     /locus_tag="CV632_RS11795"
                     /old_locus_tag="CV632_11795"
     CDS             complement(10001..11296)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014194793.1"
                     /locus_tag="CV632_RS11795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11795"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_232724451.1"
                     /sec_met_domain="LANC_like (E-value: 2e-88, bitscore:
                     290.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVCNLAKKLSDYENMKRIVNHPSNYIKIGNKTINPFNELSLS
                     HGLPALCALYGELSEQYPDEGWDLLGHQYMKKIGEQMNQHGFPSLSMFTGLAGIGLAAV
                     CLSKGGKRYQNFISTINQVIEERIGEMIEYLKQKPYPNMDDYDAISGVAGIASYCLLFP
                     QEMKKSITLILKYIIDLSQDKQMEDINVPGWYIPPMNAFSDTERRKWPSGFFNIGLSHG
                     IPALLIVLCNAKKLNIYVDGQDECIQRIADFLMKFQIKDENGSYWGTHVSLEEYKNGSV
                     LNKDTRDAWCYGTPGVAYSLLIAGKTLNNQSYIDCAVSGMKLASKRLYNIFSPSFCHGL
                     SGVAYICNRFYEETNISDFKEAACKLVDDIIKFYNEEFPFGFKNIEESEGSTKYYDYVG
                     LIDGTAGILLTILAIQNSKKTPWDCAFLLSEV"
     gene            complement(11277..13106)
                     /locus_tag="CV632_RS11800"
                     /old_locus_tag="CV632_11800"
     CDS             complement(11277..13106)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229812.1"
                     /locus_tag="CV632_RS11800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11800"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_008881438.1"
                     /transl_table=11
                     /translation="MNIKEYDDHVTIKDIVKSIRIVPKTLVLIKNVDKQSFFIIIFLSL
                     LMGGAPIVTLLGSQNLLNAIGSQNIHIIISALIFYISAVLLSEIISSFMEYYQNKFQTL
                     INYKLNLQIMDKCTRLSLRHFEDAEVYDMLQRVQNETPYKPFEVFLSILGAISAIVTFF
                     SSMMILIHWKPWVLIILIFIPLVFSFYFFKIGQREFNVSWLRAPEKRKSWYLSYLMTRD
                     NTFKEVKIYNLAGYILNKFKEINKTFVGQDIHLFKRRTVFTFIFELVEQICINTVLVII
                     IISALAGEILIGHVVGLIQALNLISSNSKKILNIIHSLYKNNLYINQLFEFLGLDEEVL
                     DKGDRFVSGIDKIENIKIRNLTFRYPTNPKVVLKNINLDINKGERIAIVGANGSGKSTL
                     IKLLLKLYEHDEDSIFYNGVSINDLDTEQLRKNIAVLFQDFVKYELKLRENVGFGDITR
                     IDRDGELKQAMERARVNFIEDLDTQLGLWFVDGVQLSGGQWQKVAIARALFRDASVYIL
                     DEPSSALDPISEKEVIDMFINMTKDKIGIFISHRLSTAKLADKIVVMNDGEIVGIGTHW
                     ELLATNELYRRMYELEALKNEEEYEHLNESAGL"
     misc_feature    complement(13197..13210)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.09"
                     /tool="antismash"
     gene            complement(13273..16413)
                     /locus_tag="CV632_RS11805"
                     /old_locus_tag="CV632_11805"
     CDS             complement(13273..16413)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014194788.1"
                     /locus_tag="CV632_RS11805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11805"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_100660522.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.1e-151,
                     bitscore: 498.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.3e-18,
                     bitscore: 61.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.7e-37, bitscore:
                     121.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDLVFKNIDTFMIRTPVLSVDNYLRFFDQKLTEGEMKERLLEIC
                     HNPVFRESILVASKSLYNKMIDFCNGKEIKKYDYFIKAIYKYLIRISTRPTPFGLFAGV
                     DFGEYTDENTSIRYGTNKYKKFARPDLEWLMKIVKKLEQEQYEQLWFTVNDSIFLKGER
                     AYLLHSTRKDDDKRVNEISVRVTLPFKITCELARHLIHYQTLKKELIKQFPNTSEEKIE
                     RFLKQLIENEFLISNLRPPLTVMDQLDYLIKRLKESHIEEWSNELIDIQQKIRTYTMTP
                     LGEGEQIYKELHKKMKKLADTKNVLQVDMKLNLQEKKLNKQVIKDVNELMHILLPFSMT
                     YQQTDSPLSRYKQEFIEKYGVDREVPLLEMLDNDLGIGAPMDYTNPKNARLAVGVPHQL
                     IDEQLREYFLHKYIEAVKDKKSITITEDEIKELGLDDYDYQSIPDSLDINVIVKCDSEQ
                     DLENNHFKYYIGPNLGSTHAGKSFGRFSYMMEGEEKLFETLNKEMLNLNNDSGEYVTCE
                     LVYLPNETRHANVTRNIHNSEYELALFTNNSKDEYHRLSLNDILIGIENDMFYAKSKTL
                     NKKLIITMNNMLNTQNAPNAIRFLYDISLDGKKIWCNFPWDTIFQDYAYIPAIEYKNFV
                     IAPRKWVINKIIKTNDKISFTEFEKRFKKFCSDYNVPKYVYLTFADNRILLNTEDENCL
                     RILHHEFNNRYGNIILSSYEEADLHLVKDDDEKEYVCELVIPLVKVKQENRQWYAKAKK
                     SNHIPSFSDIRVKLPFENWLYLKLYGVHSRADDFIAFYLSEYCREKLAKGEIEKYFFIR
                     YADPEQHIRLRLNASEEKLLQIYPDMKQWLRTLIEKRVVSRFSIDCYEREIERYGGTEL
                     IDLAENLFFFDSIVVEDILKLKRLKHIQFSDEVIGMVSIIHYMEQFGLNYESQLDFLQQ
                     QVNKQDYREDFQKNRSVYMKVCNTDNDWQGLRDTDEGMLLLNVLNQRNRSIKEYASKIQ
                     DGLEASSELSILDSVIHLHCNRLFGIDREFEKKIRTLVAHTLYALKYIKAHGLVLKN"
     aSDomain        complement(15691..15957)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CV632_RS11805_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.00E-19"
                     /identifier="RREFam001.1"
                     /label="CV632_RS11805"
                     /locus_tag="CV632_RS11805"
                     /protein_end="241"
                     /protein_start="152"
                     /score="61.0"
                     /tool="antismash"
                     /translation="VNDSIFLKGERAYLLHSTRKDDDKRVNEISVRVTLPFKITCELAR
                     HLIHYQTLKKELIKQFPNTSEEKIERFLKQLIENEFLISNLRPP"
     misc_feature    16760..16771
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(17189..17359)
                     /locus_tag="CV632_RS11810"
                     /old_locus_tag="CV632_11810"
     CDS             complement(17189..17359)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="CV632_RS11810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11810"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_008881441.1"
                     /sec_met_domain="TIGR03731 (E-value: 5.5e-22, bitscore:
                     71.1, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 4.5e-07, bitscore:
                     22.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDIVVKKQDDVVQPNVTSKSLCTPGCITGVLMCLTQN
                     SCVSCNSCIRC"
     CDS_motif       complement(17291..17359)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKFDDFDLDIVVKKQDDVVQPN"
                     /locus_tag="CV632_RS11810_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17189..17290)
                     /prepeptide="core"
                     /locus_tag="CV632_RS11810_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="17.80"
                     /molecular_weight="3263.9"
                     /monoisotopic_mass="3261.5"
                     /core_sequence="VTSKSLCTPGCITGVLMCLTQNSCVSCNSCIRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDIVVKKQDDVVQPN"
                     /leader_location="[17290:17359](-)"
                     /alternative_weights="3281.9"
                     /alternative_weights="3300.0"
     gene            complement(18031..19335)
                     /locus_tag="CV632_RS11815"
                     /old_locus_tag="CV632_11815"
     CDS             complement(18031..19335)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (89-224). E-value: 5.4e-11.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_CV632_RS11815_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013522839.1"
                     /locus_tag="CV632_RS11815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11815"
                     /product="homocysteine synthase"
                     /protein_id="WP_008881442.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.4e-16,
                     bitscore: 52.3, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.2e-10, bitscore:
                     32.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6e-09, bitscore:
                     28.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEERAFRPETLAIHAGQQPDAETGSRAVPIYQTSSYVFRDSEHA
                     ANLFGLKEEGYIYTRIMNPTNDVLEKRIAALEGGVGALALSSGQAAVFYSLINIASAGD
                     EIVSSSSIYGGTYNLFAHTLRKFGITVKFVDSSDPENFEKAITGKTKAVFAETIGNPKN
                     DVLDIEAVADIAHRHGIPLIVDNTVASPYLLRPIEFGADIVVHSATKFIGGHGNSIGGV
                     IVDSGKFDWKGSGKFPEFTEPDPSYHGLVYVDAVGEAAYITKARIQLLRDLGAALSPFN
                     AFLLLQGLETLHLRMQRHSENALAVAKFLEEEEAVESVSYPGLPSHPSHELAKKYLPNG
                     QGAIVTFEIKGGVEAGKKLIDSVKLFSHLANIGDSKSLIIHPASTTHEQLTPEEQLSAG
                     VTPGLVRLSVGTESIDDILEDLRQAIRQSQTVAVK"
     aSDomain        complement(18664..19068)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CV632_RS11815_Aminotran_5.1"
                     /evalue="5.40E-11"
                     /label="CV632_RS11815_Aminotran_5.1"
                     /locus_tag="CV632_RS11815"
                     /protein_end="224"
                     /protein_start="89"
                     /score="33.9"
                     /tool="antismash"
                     /translation="AAVFYSLINIASAGDEIVSSSSIYGGTYNLFAHTLRKFGITVKFV
                     DSSDPENFEKAITGKTKAVFAETIGNPKNDVLDIEAVADIAHRHGIPLIVDNTVASPYL
                     LRPIEFGADIVVHSATKFIGGHGNSIGGVIV"
     misc_feature    complement(19410..19423)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.04"
                     /tool="antismash"
     misc_feature    19453..19462
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(19522..20952)
                     /gene="gatB"
                     /locus_tag="CV632_RS11820"
                     /old_locus_tag="CV632_11820"
     CDS             complement(19522..20952)
                     /EC_number="6.3.5.-"
                     /GO_function="GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /gene="gatB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388551.2"
                     /locus_tag="CV632_RS11820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11820"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="WP_008881443.1"
                     /transl_table=11
                     /translation="MNFETVIGLEVHVELKTKSKIFSSSPNAFGAPPNTQTNVIDLGYP
                     GVLPVLNRQAVEFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQYDQPLGKNGW
                     IEIEVNGKKKKIGITRIHLEEDAGKLMHTGDGYSLVDFNRQGTPLIEIVSEPDIRSPEE
                     AYAYLEKLKAIIQYTGVSDCKMEEGSLRCDANISLRPLGSDKFGTKTELKNLNSFNFVR
                     MGLEYEAKRQEKILLSGGVIRQETRRFDEATKTTVLMRVKEGSEDYRYFPEPDLVMLYI
                     DDEWKERVRASIPELPDARRKRYVEEWGLPEYDAKVLTLTKEMADFFEATVANGADPKL
                     ASNWLMVEVSGYLNSEQKELHDIALTPESLAGMIKLIQNGTISSKIAKKVFKELVEHGG
                     DPEKIVKEKGLVQISDEGALRKIVLEVLDANPQSVEDYKNGKDRALGFLVGQVMKATKG
                     QANPPLVNKLLVEEINKR"
     gene            complement(20966..22423)
                     /gene="gatA"
                     /locus_tag="CV632_RS11825"
                     /old_locus_tag="CV632_11825"
     CDS             complement(20966..22423)
                     /GO_component="GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA]"
                     /GO_function="GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gatA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388550.1"
                     /locus_tag="CV632_RS11825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11825"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="WP_008881444.1"
                     /transl_table=11
                     /translation="MSLFDHTVSELHTLLQKKEVSISDLVDESYRRIGEVEEKVQAFLT
                     LNEEQARAKAKELDDKLAKGEETNPLFGLPIGIKDNIVTKGLRTTCASKILYNFDPIYD
                     ATVMERLNAAGAITIGKLNMDEFAMGSSTENSGFQLTRNPWDLERVPGGSSGGSAAAVA
                     AGEVPFSLGSDTGGSIRQPAAFCGVVGLKPTYGRVSRFGLVAFASSLDQIGPITRTVED
                     NAYLLQVIAGVDPMDSTSANIDVPNYVEALTGDIKGLKIAVPKEYLGEGVAEEVRQSVL
                     AALSVLEKLGATWEEVSLPHSKYALATYYLLASSEASANLARFDGVRYGYRTDNAKNLI
                     DMYKQTRSEGFGSEVKRRIMLGTFALSSGYYDAYYKKAQKVRTLIKRDFENVFEQYDVI
                     IGPTTPTPAFKIGEKTSDPLTMYMNDILTIPVNLAGVPAISVPCGFVDGLPVGLQIIGK
                     HFDESTVYRVAHAFEQATDYHKQKPVL"
     gene            complement(22436..22726)
                     /gene="gatC"
                     /locus_tag="CV632_RS11830"
                     /old_locus_tag="CV632_11830"
     CDS             complement(22436..22726)
                     /GO_component="GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA]"
                     /GO_function="GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gatC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011229790.1"
                     /locus_tag="CV632_RS11830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11830"
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="WP_008881445.1"
                     /transl_table=11
                     /translation="MSRISIEQVKHVADLARLAMTDEEAELFTKQLDAIITFAEQLNEL
                     DTENVPPTSHVLDMRNVMREDEPEPGLPREEVLKNAPDQQDGQFRVPAILE"
     gene            complement(22823..23152)
                     /locus_tag="CV632_RS11835"
                     /old_locus_tag="CV632_11835"
     CDS             complement(22823..23152)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CV632_RS11835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CV632_11835"
                     /product="hypothetical protein"
                     /protein_id="WP_100660523.1"
                     /transl_table=11
                     /translation="MHQLQEHRFPLGGEERAETMLCHSFPQREANLGVDAVIIPSGSLV
                     VSHAFLTVPAEWRFIAARVVFVDKLTQWDVHRVQAVERLGKSDVSFIVTSSFLSVMAYM
                     FVYVH"
     gene            23532..24305
                     /locus_tag="CV632_RS11840"
                     /old_locus_tag="CV632_11840"
     CDS             23532..24305
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886695.1"
                     /locus_tag="CV632_RS11840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11840"
                     /product="VOC family protein"
                     /protein_id="WP_100660524.1"
                     /transl_table=11
                     /translation="MNIAFDHLVHLTERPEQAKAAFEQLGFTASHGGRHLSWGTYNALC
                     YFKPLCYIEWIGIADMQTANTCGNPLITQLVADSQEGSGFSQLAFRTNDIESLAKQLRN
                     KGFTPIGPFPGSRQRDDGKLLTWSMLFLEDDTGGAFRYPFFIEWGDSDDMRMNELAPLM
                     RHPIGSPSLSSISLYTLDLDRAIDGYRRLFDLPVPEVRHDEEGTYAELTVGGIALRFYK
                     ADDRPSTRPFLCRIAGIQPRRRFELAGGTYIVSES"
     misc_feature    23545..23560
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            24435..25877
                     /locus_tag="CV632_RS11845"
                     /old_locus_tag="CV632_11845"
     CDS             24435..25877
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886694.1"
                     /locus_tag="CV632_RS11845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CV632_11845"
                     /product="flavin monoamine oxidase family protein"
                     /protein_id="WP_035499636.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-08, bitscore:
                     28.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METMISIIRNGLKKTSIPKKIVIIGAGMAGLVAASLLKQAGHRVT
                     ILEASERVGGRIYTIRSDFRDDQYFEAGAMRIPHTHRLTLEYIQKFNLPIHPFVNSTPR
                     DILYFRGIKARLSEYERHPDLFGFPIASYERGKTASELLQMAVRPVIQFIEQNPEKHWP
                     IVIEQLDRYSFDTYLRYNPFGLRLSVGAIDMIKAVLSLEGFPELSFLGLLRELMTLFTP
                     NMRFYKIVGGNDRLPKAFLPQLKDELLFSHKVQKIVQNKNSVTIHAIHTKILQPFQITA
                     DRVIVTIPFSILQFVDIEPRHSFSENKRKAIRELHYVGSTKTGIQFKTRFWEKEGLFGG
                     RTVSDLPIRYTQYPSQGIGTTGPGVVLASYTWEDDTIPWDSLSAEERLEYTLKNLAVLH
                     GEQVYREFETGTSHSWVRYPYSGGAFTLMKPNQITEISPYIATPEGRVHFAGEHTSTHH
                     GWIQGAIESGICAAYEVNNSPA"
ORIGIN
        1 cacagcaaga gtgcttttat aaattgatga tgacatgata tgctccatct ccaaaatcga
       61 taaagtttcc attcctcata ggtacgatac aaacgagttg acctttggac actgccggca
      121 atgccgatcg gtttcaatcc ctcataggta cgatacaacc ccaaaaagtg ctgttatatc
      181 aagctttttc atcccttgtt gccttcagaa taacacggtc gaaaaattct gtcaatcatg
      241 ctcgctcgtg atagctgtag gaacccagtg acaaacacaa atgtcgtcga cccctggttt
      301 ttttgcacga ttggaggtcg acgacaaacg aatcttgctt cttagtgtcc tcacatggat
      361 cttctacttt ttcagttttc ccaccactgc caccgacaat cgggtcagtt cactaatcgc
      421 cttcacgtta tatctcttgc gtcagcattc gcttcgcaat atgtatcttt tctttcacga
      481 ttccccactg ttcgtacgag gccatccatt ctattcatta tttcgctcac ctcatttcgc
      541 aattggagct cctcttcttc acacaatcgc aaactatgtc tcgaaacatc cgaacaacag
      601 ccgcccgagg gccacctctt attcgcctgc tgtttggcgc tgcttcatct ccttggccat
      661 gggccgcaag ctttcggcga tgacgaaggc gagcttagcg agcccgctcg ggagaccggt
      721 aaactgacgg ggcggcggta acattggggt caaccagaat atcttgagtt cggagtattc
      781 gggaggatct gagagcattc ccgagcattt ataagcatca aggaggagag aacactgatc
      841 actacaagag caagcgacag acggacagat cggccgatac caaatttgcc agctaccccc
      901 atattacgtt acccttttat tatgacgctt ttcacccctc cgcgtcattt tgccgctttt
      961 ttattctctt ctcccctatg atactagcag aaaaaggagg aattatgttg cgaaaatggt
     1021 tcatgtcttt gctcgctgtc gggcttgttt taggattggc cgcctgcagc ggaaaaagtg
     1081 atgcgaaagg gaaaatcgtg attaccggaa agaagtttac cgaacagatg attttgacgc
     1141 atgtactagc tgaatatgtg aaagccaaca ccgatttgga tgtcgaggtg aaggaaagtt
     1201 taggcggtgc ctttatgttg cagcaagcca ttgaaaacgg ggacatcgat atgtatgtcg
     1261 aatatacagg gacagggtat ttaaacattt taaaacagcc gtacgaccca acgaaaacgc
     1321 ccgaacaaat ctacaatgaa acgaagaaat tatataagga aaaatacaac atcgcttggc
     1381 tcaaatcact cggatttaac aatacgtatg cattagcgat gcggagagac cttgctgaaa
     1441 agctcggagt taaaacgtac tccgatttag tgaaccattc atcttccctc acatttgggt
     1501 cagacgccga gttttttgag cgaagcgacg gctatgatgg gcttgtcgat acgtacggat
     1561 tccacttcaa gaaaacggtc aacatcgatc cagacttgca atacgaagca gcgaaaaatg
     1621 gaaagattga tgtcatcacg gcctacacga cggatgcccg tattaagaaa tatgacctcg
     1681 ttgtgctcaa agacgataaa cagtacttcc caccatacta cgccgtaccg atcatccgcc
     1741 aagaagtgtt ggatgccaac ccgggattgg aagaaaaact caatcaacta gcgaatattt
     1801 taactgacga aaaaatgatg gaactcaacg gcgaagtgaa cttggaaggg aaacagccgc
     1861 gcaaggtggc gattgacttc ttgaaatcgg aaggactgat cgactagaaa gtgaggaatg
     1921 tggatgattc ggtttgaaaa cgtaacaaaa cagtatgaag atgggttcgt tgccttaaaa
     1981 aatatcaatc ttgaaatccg taaaggagag ctggttgccc tcatcgggcc gagcggttgc
     2041 gggaaaacga caacgatgcg gatgatcaac cgcttaatcg agccgacatc gggaaaagtg
     2101 tatatcgatg gacaagacat ttctgagctt gatccggtcg aactgcggcg taacatcggc
     2161 tatgtcatcc agcaaatcgg cttgtttcca catatgacga tcgcggaaaa cattgcgctc
     2221 gtgccgaagc tgaaaaaatg ggaaaaacac gcctatgaaa agcgggtcga tgagttgctt
     2281 gagctcgtcg gcttagatcc agcgacattc aagcatcgct atccgtcgga gctcagcggc
     2341 ggccaacagc aacgtgtcgg tgtcgtccgc gccttggctg ctgaaccgga catcattttg
     2401 atggacgagc catttagcgc tctcgacccg atcagccgtg aacagctgca agatgacatc
     2461 atccgtctgc aagaggagat tcacaaaacc attgtctttg tcacccatga tatggacgaa
     2521 gcgattaaaa ttgccgatcg gattgcgctg atgaaagatg gtgaaatcgt ccagtttgcg
     2581 acgccagacc aaatgcttcg gcgaccagcg aactcgtttg tccgcgaatt tattggtgaa
     2641 gatcggctgc aaatgcgaac tcgccaaaca gccgtgccaa cagcggaaga tttaatgtcc
     2701 gatgacgtcg caacgatttc gccacggcgt ggcttagccg aagcgttccg gctaatgaaa
     2761 gcgagaaaag tagacagttt ggttgtcgtc gataaaaagc actcgtttct cggcatcgtg
     2821 acactcaaac aaatcgaaca acgatacaat gaggaacatt tgcttgttgc ggacatcgct
     2881 gattacgatg tgacgacatt acaaaaagaa gcgggtgtca ccgacgtcgc tgctttgttc
     2941 caagactcgg atgtacgcat cattccagtg ctcgacggcg atcgccttgt tggcggtatt
     3001 acgcgctcga gcatgatgcg tgcgcttgct gagtggacat ttcaacaaca tgcataaaaa
     3061 aatgaatgag atataagtgg agttgaatgt cccgtttctg tccatcttgt tggcaagccg
     3121 cttgaaacga tggctcgatt aaagtaaggg ttgaactgct gataagtggc ttatggacaa
     3181 ggggatgcga ctgcttgctt gaaaagtagc cgctgaaatc actcatccgg ttggcggccg
     3241 gtttcagccg aggacgaagt gacggctgat ccgccgcctt tctgccgaat ggcataccat
     3301 gatgaagtcg cggctcatgt ctcgtcgctt ttcctcaaag ggggaagact agtccatctg
     3361 ccaacgattg tttcaccaag gaaggaataa cacgatgacc aagcggctac ccatctgccg
     3421 ctgtttttcc accaaggagg ggtacaatgg aattattgca aacgtttatc gaacgacaag
     3481 aagagatttg gatcgctttt caagagcacg tactgttatc cgctattgcc atgggcatcg
     3541 ccattgcggt tgccgtgccg ctcggtgtgg tgttgacgcg gtatcgcaaa ctcgctgagc
     3601 cgattatcag cattgccgcc atcatccaaa cgattccaag cttagcgttg cttgggttta
     3661 tgttgccgat tttcggcatt ggcaaactgc cggcgatcat cgccttgacg ctttatgctc
     3721 tattgccgat tttgcgtaac acgtacacgg gcattctcgg cgttgacccg gcgctcgttg
     3781 atgccggacg aggaatgggg atgacatcgc ggcaaatttt atggatggtt gagcttcctc
     3841 tctctcttcc ggtcattatg gccggcgtgc gcacagcaac ggtgttgacg atcggcgtcg
     3901 ccgccttagc gacgtttatc ggcgctggcg ggcttggtga cttgatcgac cgcggtttgc
     3961 gtatcgccga taaaaactta attttagccg gcgccatccc agctgccatt ttggcgattg
     4021 tgtttgactg gttgctgcgc aaagtggaaa agaaagtgac gccaaaaggg ctgtagctgt
     4081 aatcagccct ttggcgccac cccaacaaga attcgaacac cactctcccc tgcttactcg
     4141 ccccggagcg ggcgagaata tttatataga tataacccct gacgttcgta ttaatcaaaa
     4201 tgaatgcttg tcaatgatta tttgagtaag gatacaaaac ggaggaagtt cagtccagtt
     4261 tttgctgcca taaataagat ttgaaaatca ttgtgggttg ggtgattccc accccacaaa
     4321 tgatatgttt tgttcattag tcaaccgcct caccatgaaa atggacacta ccccttatga
     4381 tgattcatcc gcctcccact ccctatgtac gaactacaac agcccccttg accattctgt
     4441 ttcctcacca catgtgacat caacttaacc gctcaaatcc atcgatattt ccaatcattt
     4501 tcattcactg gtcaatgaag agcgctgatc acggcaacag caaacgataa accaaggtac
     4561 gaagcccaat ctgtaaaaaa catcatccat gtgctcattt tcttataaaa acattacatt
     4621 gagccattaa tatgaaacac agcacggata tcgccatcgc tcctttcgct aatgccagct
     4681 aaaagcaaca tcaccaccca attttctata tataggagga gaatgaacat gggagagtat
     4741 atgttagaga cccatcatgt aagcaaagcg tttgggaaac aactcgtcgt agatgatgta
     4801 tccattaaag tcaagaaaca gacggtttat ggattgcttg gaccaaatgg agccggaaag
     4861 tcaacccttt taaaaatgct gacagggctt ttgcgtccta cgaaagggga aatcatgatc
     4921 aacggccatc cttggagcag aaaagactta aaagatatcg gtgtgctgat cgaatcccct
     4981 gctctttacg gcaatctaac ggctcatgaa aacttgcttg ttcacgctaa attgcttcat
     5041 ttgcctgagt cgcggatcca agaagttttg aacatcgtcg gcttagaaaa tacagggaaa
     5101 aagaaagcat ctcaattttc cctcggaatg aaacagcgat taggaattgc caaagcgctt
     5161 ttaaaccatc caaagctgct cattctcgac gaaccaacaa acggcttgga cccattaggc
     5221 atacaggact tgcgaaaact cattcaatcg tttaccgaaa acgggatcac cgtcattcta
     5281 tcgagccata ttttgtccga agttaagcaa ttagccgatt atattggcat tatccaaaac
     5341 ggaaaactca ggtacgaagg gaaaatagac gaaagtcaag atctcgaaaa actctttgtc
     5401 gatgtagtga acgagtaatg aaggaggatg gaaatcatgc tcaatatgtt cgagtcagaa
     5461 cgtttaaaat ataagcggac gtttgcgaaa aaacttgtat tcatcgctcc gcttttcttt
     5521 gtcctgtacg ccatcatcac catgccaact ataaattcca cacacaatta ttttgaatat
     5581 gccgtattta attggtggcc attgattttt gttccgattg gaacagcctt gatcgcttcc
     5641 ttgtcaacgg taagggagaa aaagtcagga aacgataaag tgttgcgttg tcacgacatt
     5701 agcatcgtgc gtctatggtg gagcaaaatc accgtcatcg cctattacat gttgctctca
     5761 acaatagagc tgatcatctt acttgtttta ttgaaatggc tttttcccaa cagcctctca
     5821 tcagctacgg ttgccgtatt cgccagcttg gtcatttggt tgacctcttt agcctatatc
     5881 ccgatcggat tatttgtggc cgagcggttc gggatggtag tctcgatcat tgtcagtgtc
     5941 attggcctcg ccttaggggt agtcatggcc gcacaaccgt attggctgtt catcccatgg
     6001 agctggggaa tgaggatgat gtgcccgatc gtcggggttc atccgaacgg tgttcctttg
     6061 gaaaaaggga gtccgctatt ggatccttct gtcattccaa taggcctggc gattgccctt
     6121 gtcatgtttc tattgttatc ttttttaacc gccgtttggt ttgcgcgaaa ggaagtgtat
     6181 taacatgtgg tttcttcgcc ttctgtcatc cgaatggata aaaacaaaac gcacagcgat
     6241 tcggatgatg gtcatcatca cgccaatcat ttattcgctc tttatggtat ggtatttttc
     6301 gcactaccgt acctctacgt tttggcagat gaaaatctat caaggatttt ttgaagtaat
     6361 ggccgtttcc ttaccgatca ttatctccct actgactggg ctgatgtcct atcaagaaga
     6421 aaaagcagga agtttcatga acatcttgac cggtcctgta tccaaagttc aatggtatgt
     6481 tggcaaactc acgctgctca tctttattgc atgcgcggac atcttgctag cgacgattct
     6541 catgctcgtt ggaatgaaat acgtactcaa agtggcgcac attcattatc agttattttt
     6601 gcaaggagcc atgctctcca tcgtgggctc actcatcctt ttttccttgc atctgttcat
     6661 cagctttgcc tttggaatgg gagcctcgat cgcagtagga agcggcggat ttctcatttc
     6721 cgccctgatt ggcgcaactt ccttaggcga tcacgtatgg agctatattc cttgggcttg
     6781 ggctgttcgt ctctcacaat ttccgattct tatgatgccc gaagtaaagc aagccttggg
     6841 ggcgcagttg ttaaattcct tttcgctatc attatgggaa ggaatagcct atgcccttct
     6901 aagcttcatc atcgtcacca tcatcggttc gatctggttt catcgttggg aaggaaatca
     6961 accacatgaa tgaaagttca ctgctccctc tcaatgggat ggtaaaaaag gaggtttcag
     7021 agtaacgatg aaaaactcca tcttactcct catgttgatt ggaatcctct ttataggagg
     7081 ttgttcactt gtcagtgact taaaaaagac agccacacaa aatatggaga tcgatcggaa
     7141 attaccaaaa tacgagttga acaaagaaaa tttgcaagaa attcactatc aaggccgaac
     7201 gtacatgatt caagcagcaa aagtcgatcg gaatcaattg aacaaaccga tcgggaaagt
     7261 agcggagacg attaccatca atgagcatca tcaaatcttg agtaaaaaag agctgcgaaa
     7321 gatcgaagtc attcccgatc aaacggatga aaaacgaact cacttgaact ttggctgggt
     7381 atacagcatc aaaggcgtaa acccagatga agaagtagct gttacggtga accaccaatt
     7441 tttgattgct aaaagaaaat aaaggcttag agactgtcag ctagggaaag agaaattcct
     7501 ccctagctgc attctccact ctctataacg gcggaaagcc cataagattg gatgattaat
     7561 cagatagctc cttaatataa aattcaaccg tcgctccacc tttttcattg ttgtaggccc
     7621 aaatttcacc gccatgatga ttcacaattc gtttggcaat atacagtcct aatccaacat
     7681 gatttttata ctgcttatcc tggtaaaaag gctggaacaa caaagacgta tcgttttctt
     7741 taaatcccgt tcctgtatct gaacagcgaa aatagatttt ccactcattc ccctcttttt
     7801 catcatgtac ttccaactta atttctccgc tttttgtaaa cctcaggctg ttgtataaaa
     7861 tattgtccaa cactctcatt aacatcgctt catcaagtat gtaagatgat ttttgcaaat
     7921 tcacatcaaa gcaaatgttt atcgattttt gatggtaaac cattgttgag atctctagtt
     7981 ttttctcctc aaggatttgc cttacatcca cttcttttcc attcaatgag aagtggtcat
     8041 tctctacttt atagagcaac gacaaattat ctgtcaacat ggtcatcttc ccacagtttt
     8101 tgcgaataat ctctaaatgg ggagtgacat caaagtggtc caactttctc aaatcttgaa
     8161 tcaaatcaat ttgtccttgg atgaccgtta acggggttct gatatcatgt gcgatcgatg
     8221 ataccatcat ttttcgttcg tcatcggtct ttgctaaacg ttccaccatt tctttcagtg
     8281 cactgatcat ggtattaaag gaatcctgga tcttgataaa ctcttttctt ttcaaccccg
     8341 agacttgaaa atcaaaattc ccgcttgcaa tgtgatcaga agcctggagc aacaatttga
     8401 cattatgaaa caatgatttg tacagcctag atgtaaagaa aatcaaatag acaataaaaa
     8461 agatcaacgg agaaataaac atcacagcat aaatcaacac ggcttcgaag cgattttgat
     8521 tgttaatgat gaacccaaaa ggcgctttca acacatatac cgcctgaatg gcgttatcat
     8581 gcttcagggg aatgaaccga tacacatagc ttccttttac aatctcacgg ttgatcgatt
     8641 gactaatatc cacttgatcg tctataattt ctcgatcacc atacagatgc ttaccgctga
     8701 tgtctacaac ttctccctgt atcttttcac tgtaacgatg gatgggaatt aatctcccct
     8761 tgaaaatcgc ctcttcgttt tctttcacct ttttttcaat caaatccaaa tctttcacga
     8821 aataatttgt cggtttcacc acatcgttcg tggctaatgt aataatcaaa tagattaagc
     8881 ataaataagt aacggccgaa gagattgccg ttgccaacac gactttcaca actaacaaat
     8941 aaaaatctcg tttaatcgtt ttattctttt tcatcggtca catcccattt ataaccgagc
     9001 ccatataatg tttgaatata agaggtttct ggatcgacgg ccttgatttt ctttcgaata
     9061 tttttaatgc tttctgtaac agtgtctaac tggctgtcgg agtcaatccc ccatactcgt
     9121 tcaaagattc tttctttgga gaaaacgacc tttttattga gcatcaacaa cttaacaatc
     9181 tcatattctt tttttgttaa cggtaatttc tttcctttac aaaagacttc gttagccaaa
     9241 agatcaatcg taatattttt agaactcaaa agatatctct cgtttgaacg aatccgttct
     9301 tcccttctta aatgagaatc aattctcgcc tttaactcct ttaagctgaa cggtttggtg
     9361 atgtaatcat ccccaccgat cgccagagct tgaaccttat cttcctccag cgttttagca
     9421 ctaacaaata caatagggta atcaacccga tcacgaatga ttgtacacag ctccattccg
     9481 tcaattcctt ccatcatgat atccaacaca atcaaatcaa aatcgtcgtt tatcatcttc
     9541 aacgcttcta caccgctgtg gaccgtttct acctgataat gatgaagctc caaatattgt
     9601 ttaatggtgc agcaaatatc ttcatcatca tcaacgacca aaattttctt gttattcatc
     9661 ttttgatccc ccatacagtt gaatcgcatt ttaacctatt ccatccccat atcatggggt
     9721 aatctcataa caccgttgca ttgttcatag gtgcaatgtg aagctttact ctttgttgct
     9781 ttttactaaa aaatgcgcac gtcttgagtg acgcccgggt gaaagacacc tcttgtctat
     9841 gaaccttttc caacatattt gatcgatgac cggtcgatcg aacaacaccc tttttaggga
     9901 gttgttcgac cgatcggtac gccaaggtat gatggagccc cctctgcggc ttgcctctaa
     9961 ccatcgatca gtcggctttt ccattgtata taaacaacat ttaaacttca gataataaaa
    10021 atgcacaatc ccaaggcgtt tttttcgagt tttgtatagc taatatcgtc aataaaattc
    10081 ccgctgttcc atcgattagt cccacataat cataatattt cgtgcttcct tcgctctcct
    10141 caatattttt aaagccaaaa gggaattcct cattataaaa ttttattata tcatcgacta
    10201 atttgcaggc ggcttcctta aaatcgctga tattcgtttc ttcataaaat ctgttgcata
    10261 tatacgcaac tcccgataaa ccatgacaga aggaaggaga aaaaatgttg taaagccgtt
    10321 tgcttgccag tttcattccg ctgacagcac aatcaatgta tgattgatta tttagagttt
    10381 tacctgctat aagtaacgaa taagcaacac caggcgtgcc ataacaccag gcatcccttg
    10441 tatctttgtt taggacagag ccatttttgt attcctctag agaaacatga gtcccccaat
    10501 aagagccatt ttcatcttta atttgaaact tcataagaaa atcagctatt ctttgaatgc
    10561 attcatcttg cccatctacg taaatattca gttttttggc attgcacaag acaatgagta
    10621 aagcaggtat accgtgagac aacccaatgt taaagaaacc cgatggccat tttctccttt
    10681 cggtgtctga aaaagcattc attggaggaa tataccagcc aggaacgttg atatcctcca
    10741 tttgtttatc ttgagataaa tctataatgt attttaagat taacgtaata ctttttttca
    10801 tctcttgcgg aaataatagg cagtagctcg ctatacccgc tactcccgaa atagcatcgt
    10861 aatcgtccat attcggatac ggtttctgtt tcaaatactc gatcatttct ccgattcttt
    10921 cttcgatgac ttgattaatc gttgagataa agttttgata cctttttcct cccttggata
    10981 aacatactgc agcaaggccg atccctgcta atccggtaaa catggataaa gaagggaagc
    11041 cgtgttgatt catttgttca ccgatttttt tcatgtattg atgccctaat aaatcccaac
    11101 cttcatccgg atattgttcg ctcaattcgc cgtacagcgc acataaggct ggtaacccat
    11161 ggcttaaact taactcatta aacggattta tcgtcttgtt tccaatttta atataattac
    11221 ttgggtgatt gacgattcgc ttcatattct cataatccga caattttttc gcaagattac
    11281 aaaccagcgc tttcattgag atgctcatac tcctcctcgt ttttcaaagc ttccaattca
    11341 tacattcttc tgtataactc attcgtagct aacaattccc aatgcgtacc tataccgaca
    11401 atttcaccat cattcattac tacgatttta tcggcaagct tagctgttga tagacgatgt
    11461 gagataaaga taccaatttt atcttttgtc atattgataa acatatcaat gacttctttc
    11521 tcggaaatgg gatccagtgc cgagctaggt tcatccaata tatatacgga tgcatcccga
    11581 aataacgccc tagcaatcgc tactttttgc cactgtcctc ccgaaagctg aacaccgtcg
    11641 acaaaccata aacctagctg agtatctaaa tcctcgataa aatttactct cgccctctcc
    11701 atggcttgtt ttaattctcc gtcacgatca atgcgcgtaa tatcgccaaa ccccacgttt
    11761 tcccttaatt tcaattcata cttcacaaaa tcttggaaca acacggcaat gttttttctc
    11821 aattgttccg tatccaaatc attgatggac acaccattat aaaaaatgct atcctcatcg
    11881 tgctcataca atttcaataa aagttttata agggtgcttt ttcctgatcc atttgcaccg
    11941 acgatggcta ttctttcccc tttgttgatg tcgaggttaa tatttttcaa tactactttt
    12001 ggattcgttg gataacgaaa cgttaaattt cttatcttaa tattttcgat tttgtctatc
    12061 cctgatacga atcgatctcc tttgtccaat acttcttcgt ctaaccccaa aaattcaaac
    12121 agttggttga tatataaatt gtttttatac aaggaatgga tgatattcaa tattttctta
    12181 gagttgctag aaattaagtt caaggcctga ataagcccca cgacgtgacc tataaggatt
    12241 tcacctgcca acgccgaaat gatgatgata acaagtacgg tattgataca tatttgttca
    12301 acgagctcaa aaataaatgt aaaaaccgtt cttcttttaa aaagatggat atcctgcccg
    12361 acgaacgttt tgttgatttc tttaaatttg ttcaaaatat agcctgccaa gttatatatt
    12421 ttgacttctt tgaacgtgtt gtctcttgtc attaggtaag acaaatacca tgatttcctt
    12481 ttttccggtg cacgcaacca actaacatta aactctcttt ggccaatctt gaaaaaataa
    12541 aaagaaaaaa cgagtggtat gaagattaat ataatcaaca cccacggttt ccaatggatc
    12601 agaatcatca tcgatgaaaa aaaggttaca atcgccgata ttgcacctaa tatggataaa
    12661 aacacttcaa atggtttata cggcgtttca ttctgtactc tttgcaacat atcataaact
    12721 tcggcatcct caaaatgccg taaagacaat cttgtacact tgtccatgat ttgcaaatta
    12781 agtttgtagt tgatgagagt ttgaaactta ttttggtaat attccatgaa actgctgatg
    12841 atctcgctga gtaaaacagc agaaatataa aagatcaatg ccgatataat aatatgaata
    12901 ttttgggacc cgattgcatt caacaagttt tgcgaaccga gcaatgtaac aatcggtgcg
    12961 cctcccatta ataagcttaa gaaaataatg ataaaaaaac tttgtttgtc aacgttcttt
    13021 ataagaacaa gcgtcttggg aactatcctt attgatttca caatatcttt gatagtaacg
    13081 tgatcatcat actcttttat attcataaca ttttcaatcc ccgcatgcta aaatgagatc
    13141 ttcttcccgt cataaaagtt ttttcacctg aatacacaga agagagcttg tcgagctttt
    13201 gttgaaaaaa gtccaagtcg tgggtccatt tatatatcgt ctccccaatg cttggacaaa
    13261 tggataacat ctttaatttt ttaacactaa tccatgagct ttaatatact ttaatgcata
    13321 taacgtatgg gcaactaatg tacggatttt cttttcaaat tctcgatcaa tgccgaatag
    13381 cctgttacag tgtaaatgaa tcacactatc taaaatagat aattcagaag aagcttcgag
    13441 accgtcctgg atcttgcttg catactcttt tatgcttctg tttctttggt tcaaaacgtt
    13501 taataataac atcccctcat cagtgtctct taacccttgc caatcattat ccgtattaca
    13561 aactttcatg taaacagatc gattcttttg aaaatcttca cgatagtctt gtttgttgac
    13621 ttgctgttgc aagaaatcca attgactttc ataatttagg ccgaactgtt ccatataatg
    13681 aatgatggaa accattccga tcacttcatc gctaaattga atatgtttca aacgttttaa
    13741 ctttaatatg tcctctacta ctatgctatc gaagaaaaat aagttttctg caagatcgat
    13801 caattctgtt ccaccataac gctcaatttc tctttcatag cagtcgatgg aaaaacgact
    13861 caccactctt ttttcgatta acgttcgcag ccattgtttc atatccggat aaatctgtag
    13921 aagtttctct tcactggcat tcagccttaa tcttatatgt tgctccgggt cggcataccg
    13981 tataaagaaa tatttttcaa tttctccttt agccaatttt tcgcgacaat attctgaaag
    14041 ataaaaggcg atgaaatcat ccgctctaga atggacaccg tacaatttta aataaagcca
    14101 attttcaaaa ggcaacttga ctcttatatc tgaaaaactt gggatatgat ttgatttttt
    14161 cgctttggca taccattgac gattttcttg tttcactttc actaacggaa tgaccaattc
    14221 acaaacatac tctttttcgt catcatcttt aactaaatga agatcagcct cttcataaga
    14281 acttagaata atgtttccgt atctattgtt aaattcgtga tgaagaattc ttaaacaatt
    14341 ttcatcctct gtattcaaca aaatccgatt atctgcaaaa gtcaaataaa catatttcgg
    14401 cacattgtaa tcagaacaaa attttttaaa gcgtttttca aattccgtaa aactaatttt
    14461 gtcgtttgtt ttaataatct tattgatcac ccattttcgc ggtgctatga cgaaattttt
    14521 gtattcaatt gccggtatgt aagcatagtc ttgaaagatt gtatcccaag ggaaattaca
    14581 ccaaattttt ttgccatcta agcttatatc atacaaaaaa cgaatcgcat tcggggcatt
    14641 ttgtgtattc aacatattat tcatagtaat aatcaacttt ttatttagtg ttttgctttt
    14701 ggcataaaac atatcgttct ctatgccgat caaaatatca tttaagctca atcgatgata
    14761 ttcatctttg ctgttgttag taaacaacgc aagttcgtat tcgctgttat gaatatttct
    14821 tgtcacattg gcatgtctcg tttcatttgg caaataaaca agctcacaag ttacatactc
    14881 gccactatca ttattcaagt tcaacatttc tttatttaac gtttcgaaga gtttctcttc
    14941 cccttccatc atataagaaa accttccaaa acttttcccc gcatgggtcg atcctaaatt
    15001 agggccaata tagtatttga aatgattgtt ctcaagatct tgttccgagt cacattttac
    15061 aatgacgtta atgtctaatg aatccgggat gctttggtaa tcataatcat ctagacccaa
    15121 ttcttttatc tcgtcttctg ttattgttat actttttttg tctttaaccg cctcgatata
    15181 tttatgaaga aaatattctc ttaactgctc atcaatcaat tgatggggca cacctacagc
    15241 gagtcttgcg tttttcgggt ttgtataatc cataggtgct cctataccaa gatcattatc
    15301 aagcatttct agtaaaggaa cttctctgtc caccccatat ttttcgataa attcttgctt
    15361 gtacctcgaa agtggagaat ctgtttgttg ataggtcatc gaaaaaggta gaagtatgtg
    15421 cattagttca tttacatctt ttatcacttg cttgttcagt ttcttttctt gtaagtttaa
    15481 cttcatatca acttgtaaca catttttggt atcggctaac tttttcattt ttttatgtaa
    15541 ctctttatat atttgctccc cttctcctaa cggggtcatg gtatatgtgc gaatcttttg
    15601 ttgaatatca attaattcgt tactccactc ttctatatgg ctttctttca atcgctttat
    15661 cagataatca agctgatcca ttactgttaa tggtgggcgg agattggaaa ttaaaaattc
    15721 gttttctatt agttgcttga gaaaacgttc aattttttcc tcactcgtat ttggaaattg
    15781 ttttattaat tcttttttta atgtttggta atggatcaag tgacgagcta attcacacgt
    15841 gattttaaaa ggaagggtga ctctgacgct gatttcattg actcgcttgt catcgtcttt
    15901 tcgtgtcgaa tgtagtaaat atgcccgttc tccttttaaa aatatactgt cattcaccgt
    15961 gaaccataat tgctcatatt gttcttgttc caatttcttt acaatcttca tcagccattc
    16021 taaatctggc ctagcaaatt tcttatattt attcgttcca tatcttattg atgtattttc
    16081 atccgtgtat tcaccaaagt ctactcctgc aaaaagacca aatggcgttg gtctcgtgct
    16141 aattcttatc aaatacttat aaatggcttt gataaaataa tcgtattttt ttatttcctt
    16201 gccgttgcaa aaatcaatca ttttattata taaactttta ctcgctacta agatactctc
    16261 tctaaataca gggttatgac aaatttccaa cagacgctct ttcatttctc cctcagtcaa
    16321 tttttgatca aaaaatctta aatagttgtc tactgataaa accggtgttc gaatcataaa
    16381 cgtatcgatg tttttaaaga caagatcgtt cataataaag cctcctactc aatcattcac
    16441 catctccata agttaaaagg ggattctata cggaactata catacattcc atactaaagc
    16501 atgctgacac cttctgcctc gtacgaagca gaaagctggc ggcccaatct tgtgttgctt
    16561 tcgaaacgac atttggtttt tgcggggtgt ttcaaaaatt gttgtgatac ttcatgtttg
    16621 agcagtttgc ccttccttca aacttatcga ctttgttttt gaaacaacag actgaggaat
    16681 aatgacacct gtctgtgggt tcacaacatt ctgatggggt agggccgcaa atcagtcgtg
    16741 cctaacgcaa ctacatgtag caaacgttat cactccaatc ccttttatcg cccagttttt
    16801 tctttcataa aataatccgg tctgtttcat tctgagcggg cgagatgtat atgcaagtca
    16861 aaagatatta gcattgcttg ttttttatgc ttgatgtcat caaaaacatc gggtggccct
    16921 atcatgtctg tctcacccga gatataatga gtcatggacc attccaagat gatctaagga
    16981 aaaatcaaga atggacaagg gcttcttatc ctctttattt ctgcccttgt ccttactaat
    17041 ccttctcctc cttgacgatt gtcgatcaag ggtgaatgta agtgccaaat tccctttttc
    17101 ttttttgtcg gaagttagcc tatgatcgac cttgttagcg tgatttaacg ctcacatggt
    17161 tcaatgaatg tgtgatcaat cgaaaccatt agcatcgaat gcaagagtta caagatacac
    17221 aagaattttg cgtgagacac attaacacac ctgtgataca acctggcgta caaagagatt
    17281 tactcgtcac gttcggttgt accacgtcgt cctgtttttt caccacaatg tccaaatcaa
    17341 aatcatcaaa cttcgccatt ctttcatttc ctccttttta ttgttgatat ttatcattaa
    17401 ctacttgatg aaagatgtac aaaacgatta tgaattcctg cctttttcat caaatagtta
    17461 atgccaaaac aaaaaacctt ttttcgacat ttagcataaa tggaaattct aatatttttc
    17521 taatgtattt gtatatattt tttataatgt tcttaaattt attgtgtata cgagactatc
    17581 tcaaaaggtt attggcaaaa tacacaacat cttctacatg acgacttgct tgttcaagat
    17641 caggatggtg cagttgacgt aacgaggaag accgctacac gaaagcgctc cgcattcttt
    17701 tcaaatacag ggcactattc ggttcgctca atcacttcca tttgattatt caatgaacat
    17761 tagatctgca cttcgtacag ttgcacgttt aaaatgagca cacccctcac gaatttctac
    17821 accacaagtg tgtcaatgat ctatcctctt tccatataaa aaaggcatct ttcttttgat
    17881 ggcagtcgct atccgactag aatgagctca attcttcttt gggagtaaaa aagcagggct
    17941 gatccaaaac gcgcgtgcgt tttagttcag ccctcacttc tcaatcccta aatttcatgg
    18001 tagtgttgta tacgcatctg ttgatgccca ctacttcacc gccacggttt ggctttggcg
    18061 aatggcttgg cgtaagtctt ctaaaatgtc gtcgatcgac tccgtgccga cagacaggcg
    18121 aacaagacct ggggtgacac cggcggacag ctgttcttcc ggggtcagct gctcgtgcgt
    18181 cgtgctggct gggtggatga tgagcgattt cgaatcaccg atgttggcca aatgcgagaa
    18241 cagcttcacc gagtcgatca attttttccc ggcttcgacg ccacctttga tttcaaacgt
    18301 aacgatcgca ccttgcccgt ttggcaaata ctttttcgcg agttcatgtg acggatggct
    18361 tggaagccct ggatagctga cggattcgac ggcttcttcc tcttccaaaa acttagcaac
    18421 agcgagcgca ttttcgctat gacgctgcat ccgtaaatga agcgtctcta atccttgcaa
    18481 aagcaaaaac gcattaaacg gcgacagcgc tgcccctaag tcgcgcaaca gctgaatacg
    18541 cgctttcgtg atatacgctg cttccccaac agcatcgaca tacaccaaac catgataact
    18601 cggatcaggt tcggtgaact ccggaaactt gccgcttcct ttccagtcaa acttgccgct
    18661 gtcgacaatg acaccgccga tcgaattgcc gtgcccgccg ataaactttg tcgccgaatg
    18721 gacaacgata tcagcgccaa actcaatcgg ccgcagcagg tacgggctgg caaccgtgtt
    18781 atcaacgatg agcggaatgc cgtggcgatg agcgatatca gctaccgctt caatgtcgag
    18841 cacatcgttt ttcgggttgc cgatcgtttc agcaaacact gctttcgttt tgccagtaat
    18901 ggccttctca aagttttccg gatcagacga gtcaacaaac ttcaccgtaa tgccaaattt
    18961 gcgcagcgta tgggcgaaca agttgtatgt gccgccgtaa atggacgaag acgatacaat
    19021 ttcatcaccc gccgaggcga tgttgatgag cgaataaaac actgccgcct gccccgatga
    19081 cagcgccagc gctccaacgc cgccttctaa cgccgcgatt cgcttttcaa gcacatcgtt
    19141 cgtcgggttc ataatacgcg tataaatgta tccttcctct ttcaatccaa acaaattggc
    19201 cgcgtgctca ctgtcacgga atacatacga actcgtttga taaatcggta ccgctcgcga
    19261 acctgtttct gcatccggtt gttgccccgc atggatggcg agcgtctctg ggcggaatgc
    19321 acgttcttca ctcatcgttc tcatccctct ctgttttgat tcttcctctc tcgctcctct
    19381 tgatgtctat atccaactaa ttcagttggt tttgtctaaa aatctatcat ttccattgag
    19441 ggatgtcaat tgtatttttt taaaagtcta aaaaataaaa taaaaagaca aggctgccgg
    19501 tcagcagcct tgtcttttga tttatcgctt attgatttct tcaacaagca gcttgttgac
    19561 aagcggcggg ttcgcttgcc ctttcgttgc tttcatcact tggccaacga ggaagccgag
    19621 cgcacggtct ttaccgtttt tatagtcttc caccgactgc gggttggcat ctagcacttc
    19681 tagcacgatt ttgcgcagcg ctccttcgtc ggaaatttgc acaagccctt tttctttgac
    19741 gattttctct ggatcgccgc cgtgttcaac gagctcttta aacacttttt tcgcgatttt
    19801 cgacgaaatc gtgccgtttt ggatgagctt gatcatccca gctagacttt ccggcgtcaa
    19861 ggcgatgtca tgaagctctt tttgttcgga gtttaagtaa ccggatactt ctaccatgag
    19921 ccagttcgac gccagtttcg gatcagcgcc gttcgcaacg gtcgcttcaa agaagtcggc
    19981 catttctttt gtcagtgtga gcactttggc gtcatattct ggcaagcccc actcttcgac
    20041 ataccgcttc cggcgggcgt ccggcagttc cggaatcgag gcgcggacgc gctctttcca
    20101 ttcgtcgtca atgtaaagca tgaccaaatc cggctctggg aagtaacggt agtcttccga
    20161 accttctttg acgcgcatca aaacggtcgt tttcgtcgct tcgtcaaacc gccgcgtttc
    20221 ttgacggatg acgccaccgg agagcaaaat tttctcttgc cgtttcgcct cgtactcgag
    20281 ccccatgcgg acgaagttga atgagttgag gtttttcaat tccgtttttg taccgaactt
    20341 gtccgaaccg agcgggcgaa gcgaaatatt ggcgtcgcag cgaagcgacc cttcttccat
    20401 tttgcagtcg gaaacgccgg tatattggat gatcgctttt aatttttcca agtaggcgta
    20461 cgcttcttcc ggcgagcgga tgtccggctc ggagacgatc tcaataagtg gcgtcccttg
    20521 acggttaaag tcaacaagcg aatagccgtc gcctgtatgc atcaatttac cggcatcttc
    20581 ctcgagatgg atgcgggtga tgccgatttt tttctttttc ccgttcactt caatttcaat
    20641 ccaaccgttt ttgccaagcg gttggtcgta ttgcgaaatt tggtacgcct tcgggttgtc
    20701 cggataaaaa tagtttttgc ggtcaaattt tgtctcggtc gcgatttcgc agtttaacgc
    20761 catcgccgcc ttcatcgcaa actcgaccgc ttgccggttc aagaccggca gcacacccgg
    20821 ataccctaaa tcgatgacgt tcgtttgcgt attcgggggc gcaccgaatg cgttcgggct
    20881 gcttgagaaa attttcgatt ttgttttcag ctcgacgtgc acctcaagtc cgatgaccgt
    20941 ttcaaaattc atcgtctatc cccccttata acaccggttt ttgcttatgg taatcggtcg
    21001 cttgttcaaa ggcgtgagcg acacggtaga ccgtgctttc atcaaaatgc ttgccgataa
    21061 tttgcaagcc gaccggcaag ccatcaacaa agccgcacgg cacagaaatc gccggtacac
    21121 ccgcaaggtt gaccggaatc gttaaaatat cgttcatata catggtcagc ggatcgctcg
    21181 ttttctcgcc gattttaaac gctggcgtcg gcgtcgtcgg accgatgatg acatcgtatt
    21241 gttcaaagac attttcaaag tcgcgtttaa ttaacgtccg cactttttgt gcctttttgt
    21301 aatacgcatc gtaatagccc gagcttaagg caaacgtccc aagcataata cggcgtttga
    21361 cttcgctgcc gaacccttcg ctccgcgttt gtttgtacat atcgatcaag tttttcgcat
    21421 tgtccgtccg gtagccgtag cggacaccgt caaagcgggc aaggttggca gatgcttccg
    21481 acgaagcaag caaatagtac gtcgccaagg catatttcga atgtggcagc gacacttctt
    21541 cccatgtcgc tccaagcttc tccagcacac tgagtgccgc aagcaccgac tggcgtactt
    21601 cttcggcgac gccttcgcct aaatattctt ttggcacagc gattttcagc cctttgatat
    21661 cgcctgttaa cgcctcaacg tagtttggca cgtcaatatt cgccgacgtc gaatccatcg
    21721 ggtcaacgcc agcgatcact tgcaacaaat atgcattatc ttctaccgtg cgcgtaatcg
    21781 gaccaatttg gtcaagcgac gacgcaaacg cgacgagccc gaaacgcgaa acgcgaccgt
    21841 acgtcggctt caatccgaca actccgcaaa acgctgctgg ctggcggatc gaaccacccg
    21901 tatctgatcc tagcgaaaac ggcacttcgc ctgccgccac tgccgcggcc gaaccgccgc
    21961 ttgaaccgcc tggaacgcgc tccaaatccc atgggttgcg cgtcagctgg aacccggagt
    22021 tttccgtcga cgaacccatg gcaaactcgt ccatgttcag cttcccgatc gtaatcgcgc
    22081 ccgcagcatt cagccgttcc ataacggtcg catcgtaaat cggatcaaag ttatataaaa
    22141 ttttgctggc acatgtcgtg cgcagtcctt tggtgacaat gttgtcttta atgccgatcg
    22201 gcaagccaaa cagcgggttt gtttcctcgc ctttcgccag cttgtcgtca agctctttcg
    22261 ctttcgcccg cgcttgttct tcgtttaacg ttaaaaacgc ttgtactttt tcttccactt
    22321 cgccgatgcg gcggtatgat tcatcaacta aatccgaaat ggacacttct tttttctgca
    22381 ataacgtatg taattcggac accgtatggt caaagagcga cataaatccc cctccttact
    22441 ctaaaatggc tggtacacgg aattggccgt cttgctgatc cggcgcgttt ttcaacactt
    22501 cttcacgcgg cagtccaggc tccggctcat cttcgcgcat cacgtttctc atatcgagca
    22561 cgtgcgatgt cggcggtaca ttttccgtat ccagctcatt caactgctcg gcaaatgtaa
    22621 tgatggcgtc aagctgtttc gtaaacagtt ccgcctcctc atccgtcatc gctaaccgcg
    22681 ctaaatccgc gacatgtttt acttgttcaa tcgaaattcg cgacatcgta ttcacctccg
    22741 acatggtcga ccttccacaa tactatgatg ataccaaaat ttaaggaaat aaagcaacat
    22801 tccggaccaa tttgagtggt tgtcaatgga catacacgaa catatacgcc ataactgata
    22861 aaaaggaact tgtaacgatg aacgaaacat cgcttttgcc taagcgctcg acagcctgaa
    22921 cacgatggac gtcccattgc gtcagtttat caacaaaaac aactcgagcg gcaataaatc
    22981 gccattcagc cggaacagtc agaaatgcgt gagaaacaac aagagatccg cttggaataa
    23041 taacggcgtc aacaccaagg tttgcttcac gctggggaaa agaatggcac agcatcgttt
    23101 ccgccctttc ttcaccgcca agagggaacc gatgctcttg cagctgatgc acatcacctt
    23161 gcgagaaagc gcttcattag aattgaacac tccccccacc tacgtttaca cttaaagatg
    23221 ggagatgctt gagaatgctc gccacagcag gctgtcaacc aagacatcct tatacgttcc
    23281 acgcttggtg aaagactccg attcatctcc cacttgtgct catgcgtgaa ggtgggaacc
    23341 ttctcggttt agaaaccacc tcgaacaaaa catagattcc cgtgccgaat cattgacctc
    23401 aaatcgaaga catccagttg gacttagatt tcatcgccca ccgtacggtc gataacgaat
    23461 gcatcatctg tcaaacgaaa agaagtgctg tcctactgat ccattctcat ataggaaagg
    23521 agcccaacgt catgaatatc gcgtttgacc atctcgttca tttaaccgag cgccccgaac
    23581 aagcgaaagc agcgtttgag caattagggt ttacggcctc ccatggcggc cgccatttgt
    23641 catggggaac gtataacgca ttgtgctatt tcaagccgct ctgctacatt gaatggatcg
    23701 gcatcgctga catgcagacg gcgaacacat gcggaaatcc gctcatcacc cagcttgtcg
    23761 ccgacagcca agagggaagt ggcttttctc aattagcgtt ccggacgaac gatatcgaat
    23821 cattggcaaa gcagctacgg aacaaaggat tcaccccaat cgggccgttc cctggcagtc
    23881 gccagcgcga tgacggcaag ttgctcacgt ggtcaatgct gtttcttgaa gacgacacag
    23941 gcggcgcgtt ccgttacccg tttttcatcg aatggggcga cagcgacgac atgcggatga
    24001 atgaattggc gccgctgatg cgccacccga tcggttcccc ttctttgtcg tcgattagcc
    24061 tctatacgct cgatctcgat cgcgccatcg acggctaccg ccggctgttt gacttgccgg
    24121 tacccgaggt taggcacgat gaagagggaa catatgcgga gctaaccgtt ggcggcatcg
    24181 ctctccgctt ttacaaagcc gacgatcgcc cgtcaacaag gccattttta tgtcggatcg
    24241 ccggcattca gccaaggcgc cgcttcgagc tagctggagg gacgtatatc gtttctgaat
    24301 cgtgacagat gcttttcaca tatccccctt tgctgctgaa taggatggaa taaccgtagt
    24361 ttcatccaaa tgtagtgaaa atggcaaagg gggattgaca cgtggcgcat ccctatattt
    24421 ctccgagact gcccatggag acgatgatct cgattattcg aaacgggtta aagaaaacat
    24481 ccataccgaa aaagatcgtc attatcggtg ctggcatggc cgggcttgtg gcggcatcac
    24541 tgctgaaaca ggcgggccat cgcgtcacca ttcttgaggc atctgagcgg gtcggcggcc
    24601 gaatctacac gatccgatcc gactttcgcg atgaccagta tttcgaagcg ggcgcgatgc
    24661 gcattccaca cacccaccgc ttgacgttgg aatacatcca aaagttcaac ttgccgatcc
    24721 acccttttgt caacagcact ccgcgcgaca ttttgtattt tcgcggtatc aaagcgcgcc
    24781 ttagcgaata cgaacggcat cccgacctct ttggctttcc catcgcttcc tatgaacgag
    24841 gcaaaacggc ttccgaacta ttgcaaatgg cggttcgccc agtcattcaa ttcattgaac
    24901 aaaacccaga gaaacattgg ccgattgtca tcgaacagct cgaccgctac tcgtttgaca
    24961 cctatttgcg ttacaacccg ttcggtctaa ggctatcggt aggtgctatc gatatgatca
    25021 aagcggtcct ctcgctcgaa ggattcccgg aattgtcgtt tcttgggctg ttgcgcgaac
    25081 tgatgacatt gtttacaccg aacatgcgct tttataaaat tgttggcggc aacgatcggc
    25141 ttccaaaggc ctttttgccg caactgaagg atgagctgct ctttagccat aaagtgcaaa
    25201 aaattgtcca aaacaaaaac agtgtcacca ttcatgcgat ccatacaaaa attcttcagc
    25261 catttcaaat cacagccgat cgagtgatcg tcaccatccc gttttcgatt ttgcaatttg
    25321 tcgacattga accacgccat tcgttttccg agaataaacg aaaagccatt cgcgaacttc
    25381 attatgtcgg ttcaacgaaa accggcatcc agtttaaaac acgtttttgg gaaaaagaag
    25441 gcttgttcgg gggacgaaca gtgtccgatt tgccaattcg ctacacccaa tatccaagcc
    25501 aaggcatcgg cacgactgga ccaggcgtcg tattggccag ctatacgtgg gaagacgaca
    25561 cgatcccgtg ggacagccta agcgctgaag agcggctcga atacacgtta aaaaacttag
    25621 ccgtcctcca tggtgaacaa gtgtaccgcg aatttgaaac cggaacaagt catagctggg
    25681 tacgctatcc atactcgggc ggcgccttta cactgatgaa gccgaatcaa ataacagaga
    25741 tttcccccta tattgctacc cccgaaggaa gggttcattt tgctggggaa catacttcca
    25801 cgcaccatgg ctggattcaa ggagccattg aatccggcat ctgcgccgca tatgaagtaa
    25861 acaattcgcc ggcttaaaga cttagcggca aaccaccccg ccatcatcgc tgcccgcgac
    25921 gatggcggaa catgctcatc tgctcatata gcgtcggaac atccccggca ctcacgatca
    25981 gctcgagatc ttgtggggcg gcaaatcctt gttgaaccgt gtgccgaagc aagtcgagga
    26041 gcgggtcaaa aaagccgtcc acattgagca ggccgatcgg tttttggtga aggccgacac
    26101 gcgaccacga cagcacttca aacagctctt cgtacgttcc atatcctcca ggcagggcga
    26161 taaacccgtc ggctgcttcg ttcattttcg ccttgcgcgt atgcattgta tcgacgacga
    26221 ccaactcgct caaccgatca tgagctactt ctcgatcttt caaaaactgt ggaatgatcc
    26281 cgacgacacg cccttgatgg cctagcactg cctcggccac ctctcccatc agcccagcct
    26341 ttcctccgcc gtaaatcagc gtaatgccgc ggcgagctaa aaacatccct agctcctgcg
    26401 ctgcttcttt ata
//
