LOCUS       NZ_NNBO01000008        22193 bp    DNA     linear   CON 14-AUG-2024
DEFINITION  Kitasatospora sp. CB02891 scaffold8, whole genome shotgun sequence.
ACCESSION   NZ_NNBO01000008
VERSION     NZ_NNBO01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Kitasatospora sp. CB02891
  ORGANISM  Kitasatospora sp. CB02891
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Kitasatospora.
REFERENCE   1  (bases 1 to 354875)
  AUTHORS   Pan,G., Xu,Z., Guo,Z., Ma,M., Yang,D., Zhou,H., Gansemans,Y.,
            Zhu,X., Zhao,L.-X., Jiang,Y., Cheng,J., van Nieuwerburgh,F.,
            Suh,J.W., Duan,Y. and Shen,B.
  TITLE     Discovery of the Leinamycin Family of Natural Products by Mining
            Actinobacterial Genomes
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 114 (2017) In press
REFERENCE   2  (bases 1 to 354875)
  AUTHORS   Pan,G., Xu,Z. and Shen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUL-2017) Chemistry, The Scripps Research Institute,
            130 Scripps Way, Jupiter, FL 33458, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 04-APR-2016
            Assembly Method                   :: CLC NGS Cell v. 7.5.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002803145.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:20:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,223
            CDSs (total)                      :: 7,128
            Genes (coding)                    :: 7,004
            CDSs (with protein)               :: 7,004
            Genes (RNA)                       :: 95
            rRNAs                             :: 8, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 32 of 124
            Pseudo Genes (incomplete)         :: 102 of 124
            Pseudo Genes (internal stop)      :: 10 of 124
            Pseudo Genes (multiple problems)  :: 18 of 124
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:31:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 46428
            Orig. end                         :: 68621
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NNBO01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22193
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22193
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22193
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12193](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12193)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(45..59)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    complement(312..325)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(385..399)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.54"
                     /tool="antismash"
     misc_feature    complement(844..859)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     gene            complement(1121..2551)
                     /locus_tag="CG736_RS18945"
                     /old_locus_tag="CG736_18885"
     CDS             complement(1121..2551)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004990716.1"
                     /locus_tag="CG736_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18885"
                     /product="APC family permease"
                     /protein_id="WP_100587387.1"
                     /transl_table=11
                     /translation="MSTTRLLRRKPVDTLIAEAGGTGAGHLRRSIGLWQLSAIGIGATV
                     GTGIFFVLTTSVPVAGPAVVVSFVIAAVTAGLTALCYAELASAIPVAGSSYSYAYATMG
                     ELVAFGVGVCLLMEYGVSASAIAVTWGQYLDQFADLAFGLHLPAALTAPPGENGVFNLP
                     AVVLVALVTVLLIRGVGESAKVNAVMVTIKLAILVLFVAIGLTGFHAGNFTPFAPNGWG
                     GVQTAASTIFFSFIGLDAVSTAGEEVREPRRTMPLAILISLGVVTLLYIAVAVTAVGAQ
                     PWQQFDGQKAGLAQILQDVTGQSWPALVFAGGAIVSIFSITLVVIYGQTRILYAMGRDG
                     LLPRPFTRVSPRTGTPVWNTVVVGAAVALLAAVFPLRLLADMTSMGTLVAFTAVSVGIV
                     VLRRTRPDLPRGFKVPFYPVTPVLSAGFCVYLITKLHRDTFIAFAIALALAAVLYFTYS
                     AKHSRLAAPRTEEPADPS"
     misc_feature    2588..2602
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(2640..4061)
                     /locus_tag="CG736_RS18950"
                     /old_locus_tag="CG736_18890"
     CDS             complement(2640..4061)
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983439.1"
                     /locus_tag="CG736_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18890"
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="WP_100587624.1"
                     /transl_table=11
                     /translation="MLLIILLAVQATRVQVFQKQELDHNSANQRATIQRYAQPRGNLIA
                     GQPVTGSVATGGRLAYQRTYTDGPLYAAVTGYSSQIYGNTQLEGVYDDLLTGTDPRLTG
                     WAVWDAITRNQQPGGDVVTTIDPAVQRAAMQGLGGQQGAVAAIEPATGRILALASTPSY
                     DPGAIAGAGAADQAAWEKLQADPDQPMLNRALRQIYPPGSTFKVVTAAAALANGTVTDI
                     QAPTGAPFPYVMPGTTTTLNNDTSACDREGLSLDEAMTLSCNSVLGWLGVQTGLDPMVA
                     MAKNFGFDDAKLDVPVRAARSNFDTRMNSSQLALSSIGQYNTAATPLVMAMVAAGVAAD
                     GRVMHPQLVDRLTKADGTQVQLMRPALYRQAFGPGVAAELRRLMVNVVNNGTGGNAQIP
                     GAEVGGKTGTAEHGVDNSGTPYAWFIAWARPAGSTATPPVAVAVVVADSTATDVTGGRL
                     AAPIAKAVMQAVLDR"
     gene            complement(4148..5497)
                     /locus_tag="CG736_RS18955"
                     /old_locus_tag="CG736_18895"
     CDS             complement(4148..5497)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137695.1"
                     /locus_tag="CG736_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18895"
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="WP_100587388.1"
                     /transl_table=11
                     /translation="MATDSATRAAAWTPGARRPRRWTELVLVVAAVGLAVFGYVEVGVD
                     IDGKAPPDAAQYGAALGVLALLAHGAVRWRAKWADPLLLPIAVLLNGIGLVVIYRLDRN
                     TPHHEAAPTQLLWSTLGVGLFIAVLLLLRDHRRLQRYAYVGAFVALVLLVLPVFFPPVY
                     GSRIWITLGPLSFQPGEFAKVLLAIFFAAYLARHRDALALTGRRVLWFQLPLGRVLGPV
                     LLIWAAFVGVLVLETDLGTSLLFFGLFVVMLYVATARTGWIVIGLLLSAVAAVGVGWLS
                     PHVHSRVTDWLHPLASIRAGQGANQIAQSLFAFAWGGQLGTGLGLGHSALIGFATKSDF
                     ILATIGEELGLTGLLAVFLLYALLVSRGFRTGIALRDPFGRLLAIGLAALVAIQVFVVA
                     GGVLDLIPLTGMTLPFIAQGGSSVVTNWIIVALLVRMSDLARRPDPGEAA"
     misc_feature    complement(5315..5317)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5585..6088)
                     /locus_tag="CG736_RS18960"
                     /old_locus_tag="CG736_18900"
     CDS             complement(5585..6088)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137694.1"
                     /locus_tag="CG736_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18900"
                     /product="DUF1269 domain-containing protein"
                     /protein_id="WP_100587625.1"
                     /transl_table=11
                     /translation="MSNLFAIAYPDVATAQKVRDELIGLQKQRLIDLEDIVVVERREDG
                     KIKLHQAVSNTGLGAASGALWGGVIGLLFLMPVIGAAIGGATGAAVGASTDTGVDDDFM
                     RKVGEKLAPGSAAVFALVRTATQDKVIPAVAQFGGELLQTSLSHEEEEHLREIARAANP
                     ASTL"
     misc_feature    6150..6163
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.74"
                     /tool="antismash"
     misc_feature    complement(6150..6165)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            complement(6194..6844)
                     /locus_tag="CG736_RS18965"
                     /old_locus_tag="CG736_18905"
     CDS             complement(6194..6844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004956394.1"
                     /locus_tag="CG736_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18905"
                     /product="ABC transporter"
                     /protein_id="WP_100587389.1"
                     /transl_table=11
                     /translation="MTVRTLTRYHLELLLRSQRWLPPGLVYLVLMGLGVSGGDDALSAA
                     AFSAGLLVPVTGWLVRAAVTAEPAQSRACLVAAAGWRRVHLSALVAAALAGLALGVAGL
                     AGVLLVGSGGGGGAVAAGLSATVVCVLTGAAVGAVCNRPVVTGAQYAVPLGLGAMVLVL
                     LLPGSPANAVVRALVLGSRHGATAVPWWTLPGAALLAGAAGWAAVAVAVRRGE"
     gene            complement(6841..7671)
                     /locus_tag="CG736_RS18970"
                     /old_locus_tag="CG736_18910"
     CDS             complement(6841..7671)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852476.1"
                     /locus_tag="CG736_RS18970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18910"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_100587390.1"
                     /transl_table=11
                     /translation="MTVRLAGVGKRYGRGGPWVLREVELTLRPGGLVRIEGANGSGKST
                     LLKLLAGIERAERGTVEAPDGRAYVPERFPPALPFDVRDYLCHLGRIRGLAAGEARRRA
                     DHWLERFGITGYAGTPIGRLSKGTCQKVAVAQALLAEAELLLLDEAWTGLDQAARGELD
                     GAVAERAAAGALVVFVDHDPTRLAGLTTAVHRVDGGTLHEVPLPAADGDGPRTALVVEA
                     ETLPEWLPGRPERKPLADGATRLDVPAAHSDALLRRLLAAHPPVHIRSVQEEAS"
     gene            7767..9086
                     /locus_tag="CG736_RS18975"
                     /old_locus_tag="CG736_18915"
     CDS             7767..9086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137690.1"
                     /locus_tag="CG736_RS18975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18915"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_100587391.1"
                     /transl_table=11
                     /translation="MITHTKKRRTARGAALLGALTIVAGTVLGTLPAHADEPGAPPAAT
                     EAPKVDLILDGSGSMRTADIQGKSRIAVAQQSINEVIDALPAETEFGLRTLGATYPGND
                     QKEGCKDTKQLFPVGRTNKVEAKTAVATVRPTGWTPIGVALRAAAQDLGTGPTTRRIVL
                     ITDGEDTCAPPDPCDVARELASQGIHLVIDTLGLAHDDKTRQQLLCIANATGGTFTDVR
                     SQDQLTQRVKQIVTRAQDTHTVTPAKVTGAEQCSSAPILTPGVYSDREKFSEHRVYRVP
                     VKAGQELRASVSVTPDRAVARDYGVLLQATDSSGQELVRGSDAGSGRTDVASTGVRWSA
                     PGTESATPSPTSGAAASTDRTVCLIVSNSFAGQAGVQADAGLPLELTVDVAAASPAPDG
                     PAMGLGRGWILLGVLTLAGLLAGLIFGWLARWRIAVWREN"
     gene            9089..9952
                     /locus_tag="CG736_RS18980"
                     /old_locus_tag="CG736_18920"
     CDS             9089..9952
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137689.1"
                     /locus_tag="CG736_RS18980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18920"
                     /product="peptidase"
                     /protein_id="WP_100587392.1"
                     /transl_table=11
                     /translation="MRKLFALAAPAAALTGLLLLAPTATAASPSPSASGTAKPVLNSVG
                     TSFLTATTLAAGQDADVPVSTGDYLYWAFPASEGQTATVEVKVTLPDAADRHGPQTWTV
                     ELFDGLRRRQACTSGPQNGTAADSATTVALSCTLRQIRSWAEPWSGDPLPGTYYIRLST
                     SDIPQQDLGLASQVHVHVAAKGGVNDAQPEGGSLKAPLVPPVNAGSTASGSAATPAPSS
                     SAAYAAAPVAEETHWYSDLFSGWNTRWWWTVAGGILAALAGVLGYTLTRHPRGHRPHHH
                     HPHLSE"
     gene            complement(10001..12193)
                     /locus_tag="CG736_RS18985"
                     /old_locus_tag="CG736_18925"
     CDS             complement(10001..12193)
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849643.1"
                     /locus_tag="CG736_RS18985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18925"
                     /product="terpene synthase family protein"
                     /protein_id="WP_100587393.1"
                     /sec_met_domain="T1TS (E-value: 2.1e-84, bitscore: 278.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFELPDFYVPYPARINPHYEKARVHTKEWARDFGMLEGSGIW
                     EEHDLDSHDYALLCSYTHPDCDSEALDLVTDWYTWVFFFDDHFLEIFKRTLDREGGKAY
                     LDRLPAFMPMDLADGFPDPTNPVEAGLADLWQRTVPHMSADWRSRFAESTRHLLNESLW
                     ELSNINEGRVSNPVEYIEMRRKVGGAPWSAGLIEYAAYAEVPESVAYSRPLRVLRDAFS
                     DGVHLRNDLFSYEREIQEEGELSNGVLVLETFLGCSTQEAADAVNDLLTSRLQQFENTA
                     LTELPGLFAEHALDPEEIARVLAYVKGMQDWQSGGHEWHMRSSRYMNGGGAAAPTFGPK
                     GLGTSAANIRLAAGIRGLRSFAHVPHRRVGPSLMPDFPMPYAVTINPHVDASREYVVRW
                     SHEFGLLDPEPGVPASDIWTEQKLRDYDFPLCAAGIDPDGTAAELDLSSAWLTWGTYAD
                     DYYPPVFGAPRDLAGAKLANERLYALMTLDGSLPFEPRNALEAGLADLWQRTIVPFSTA
                     ARAKFRKAVGDMIDSWLWELANGAQNRIPDPVDYIEMRRATFGSDLTMSLSRLGRGETI
                     PDEVYRSGTMRAIENSAADYACLVNDLHSYQKEIEYEGEVHNLVRVVENFFSCDYPVAV
                     DIVADLMGSRLSQFQHVVQGELPLLKQDFAIDGEASEALDGYVHELEDWMAAVLHWHQQ
                     CRRYSEDVLKRHFAPEVPVTAELGMSAMRILAELRA"
     misc_feature    12177..12192
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            12379..12699
                     /locus_tag="CG736_RS18990"
                     /old_locus_tag="CG736_18930"
     CDS             12379..12699
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490064.1"
                     /locus_tag="CG736_RS18990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18930"
                     /product="hypothetical protein"
                     /protein_id="WP_100587394.1"
                     /transl_table=11
                     /translation="MAFTDETWRLVHGEDLVGEIRIDDADFPWLHGEFTPGPGWPGFAP
                     RFAECRELAEAEEWDAWGQVHLRLEQELTLHAPEGPMAEFLLHIEPPRAWFRFSEEPFE
                     DD"
     gene            complement(12707..13207)
                     /locus_tag="CG736_RS18995"
                     /old_locus_tag="CG736_18935"
     CDS             complement(12707..13207)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CG736_RS18995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CG736_18935"
                     /product="hypothetical protein"
                     /protein_id="WP_100587395.1"
                     /transl_table=11
                     /translation="MSTWHPPAPPGLNTGPLPRRSVLGLWLQFGLQWFWLPFRIVWDFL
                     DNSVAFDGTAEPGVAKFVLTPSRYRLERQGTREEWEAWAGRALDRGIERGLATVRRNQE
                     FNANKYRYKFKGDELVPRTTIRRRYYRGIGLDGLAVLAARRGWQVDWSSGTAEVRVFRP
                     QAG"
     gene            complement(13204..13911)
                     /locus_tag="CG736_RS19000"
                     /old_locus_tag="CG736_18940"
     CDS             complement(13204..13911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CG736_RS19000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CG736_18940"
                     /product="hypothetical protein"
                     /protein_id="WP_100587396.1"
                     /transl_table=11
                     /translation="MTTPQNGPAESLPADILPDDALDIRWVVPAQFHSLGVELPEQERE
                     AHLAEVAAEIWCGGTEFQRSTVASWYSDIAATAGEEGAVYSGFLLAGTEDDRVTVATLV
                     IQADQADTADADTVAAAIQDMLSLDPANEVFRVPAPVGPVVVAVAGSLAEVDDEFGNKA
                     KLELAQASAYIPVQGADTLVTMTISTPMLIDFPEYVTMLAGLVETVVYDRPGTQPATAP
                     PGPDQAKITEAFG"
     gene            complement(13908..15206)
                     /locus_tag="CG736_RS19005"
                     /old_locus_tag="CG736_18945"
     CDS             complement(13908..15206)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044554.1"
                     /locus_tag="CG736_RS19005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18945"
                     /product="putative T7SS-secreted protein"
                     /protein_id="WP_100587397.1"
                     /transl_table=11
                     /translation="MSSKADFPTLGFDPAPGSPENVDGLVDKLNRASVAMESAHRTLVA
                     VGQGGSVWEGDAAKAFAGKVGELPRYLADSVDAMRQASGQLDSWKNQLVSYQGVARRYE
                     AEAAEAKRRMENAENVKQNAVERFDLAADSPAFALIGKRFDDDAALADAQRRIDAASAE
                     YSTAERQLEDANRELRAIKDELEAIVKQAKELHEHHQDDADRTAKALRRANQNAPEISA
                     WEKIGNGFKSVGKKIKDWATKHADLLKKIGDIAGGVSAVLGIAALATLWCPPLSAALGV
                     AAGGASAVALGAHGMAKLGGADVSWTTIALDGVGVVPFVGGAAKGIGGAAKGVTAIAKG
                     EGLAAGGAKLMEAGQAIKATHLEGGLLHNKVLTPLFTKTPLKKLPGIGSLGEDGQKVFS
                     LPVESWWSRGTQIGMKGSGLIMHAPTLYQEVTS"
     gene            complement(15203..15499)
                     /locus_tag="CG736_RS19010"
                     /old_locus_tag="CG736_18950"
     CDS             complement(15203..15499)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137680.1"
                     /locus_tag="CG736_RS19010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18950"
                     /product="hypothetical protein"
                     /protein_id="WP_100587398.1"
                     /transl_table=11
                     /translation="MGAYFRVEVSELDRLVKQLKSSQQDMREALRAMKDTGPKTTGSKN
                     LDHACDDFNDSWQDAITRISQGVEALEGKLQETCKGYSETDQAIRDMFTGAAA"
     misc_feature    complement(15450..15465)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(15693..15706)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            complement(15806..16228)
                     /locus_tag="CG736_RS19015"
                     /old_locus_tag="CG736_18955"
     CDS             complement(15806..16228)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CG736_RS19015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CG736_18955"
                     /product="hypothetical protein"
                     /protein_id="WP_100587399.1"
                     /transl_table=11
                     /translation="MQWYEGEDRPSPEPGGQVAELAAFLRGAAARSAPALLWSEQEPAP
                     DGSAGALAAALERELARPVRPVPERPAGPWQRGRSAVLLVQRRAAAEIHLSPPPGSAAR
                     RSTLRLRASQCLLVPADWSYRLDPRSPAQPLALALP"
     gene            16546..16743
                     /locus_tag="CG736_RS19020"
                     /old_locus_tag="CG736_18960"
     CDS             16546..16743
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CG736_RS19020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CG736_18960"
                     /product="hypothetical protein"
                     /protein_id="WP_100587400.1"
                     /transl_table=11
                     /translation="MKRALALVAVTAAALFAAAPLASATTVPAPAGSATQLSVGLPNTP
                     LDGDTSWGGACETPLCKPWS"
     gene            16776..17000
                     /locus_tag="CG736_RS19025"
                     /old_locus_tag="CG736_18965"
     CDS             16776..17000
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009317107.1"
                     /locus_tag="CG736_RS19025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18965"
                     /product="response regulator transcription factor"
                     /protein_id="WP_043915720.1"
                     /transl_table=11
                     /translation="MHTIGIAFSRRELQVLHLVGEGASYATIARRLGLSPHTVDTYLRR
                     IRAKSGVSSQVQLALLASRLPTQPAQAAA"
     misc_feature    17044..17054
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            17117..17881
                     /locus_tag="CG736_RS19030"
                     /old_locus_tag="CG736_18970"
     CDS             17117..17881
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137687.1"
                     /locus_tag="CG736_RS19030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18970"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_232734064.1"
                     /sec_met_domain="Abi (E-value: 4.1e-13, bitscore: 44.1,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQERRPGWLGPAALFLTATVMASGLMLALQPLTGLPGEVLELVQF
                     GPAVGVAVVALVRPSQVRGLLTAGGPRGPRGAVLLSALAIIAVAVAGSLLLHGSVPVRD
                     PNGLVAPFWVVAVAQFVGACGEEIGWRCFLQPLLRTRFGPLGSSVAVGLLWGCWHLQIF
                     AAAPAYAIGFLAATTAMSVLLGLAWERIGAHRLLVAGGFHTLVNLGMLLFLDEESGAVE
                     PMVLFGVAGVLVALPWVLAALRPARTDRLATT"
     gene            17878..19155
                     /locus_tag="CG736_RS19035"
                     /old_locus_tag="CG736_18975"
     CDS             17878..19155
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137686.1"
                     /locus_tag="CG736_RS19035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18975"
                     /product="histidine kinase"
                     /protein_id="WP_100587401.1"
                     /transl_table=11
                     /translation="MTDRQKRFRGPLVALVRCQLLSLASLVTSLRSLAVLGALALLPVG
                     AGLPLLPPAARMLRRGSDLERDRTARWTGTVIDAPEPLPTAPTVTGRGAAVLGSTAFWR
                     DVAWCCFGPWSTGLLVSVPPTLVGYGLFGAVAQPFLWPYLGPGNWYAFIPVESTTTAIA
                     AAALGLGFVAAGLWLSVPALVRYGEWTGRLLGDPYAARLERRIGQLTDSRADALDTQAA
                     ELRRIERDLHDGAQARLVALGLTLDQADRLVDSDPTAARRLLGEVRASSERALQELRDL
                     VHGILPPVLADRGLPDAVRSLALDAFLDVEVDAELPGRLPAAVEGAAYFAIAELLANAG
                     KHSGGSTVRIRLRCADGLLRATVTDDGRGGADPARGSGLAGVRRRLAAFDGTLALVSPP
                     GGPTTATLELPCASSSPKTSSSSVTA"
     gene            19107..19751
                     /locus_tag="CG736_RS19040"
                     /old_locus_tag="CG736_18980"
     CDS             19107..19751
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985496.1"
                     /locus_tag="CG736_RS19040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18980"
                     /product="response regulator transcription factor"
                     /protein_id="WP_100587402.1"
                     /transl_table=11
                     /translation="MRVVLAEDLFLLRDGLSRTLAEHGFDVAAAVETGPELLRALRELR
                     PDVAVVDIRLPPTHTDEGLQAALTVRRERPALPVLVLSQYVEQLYAQELLADGHGAVGY
                     LLKDRVTHTAQFVDAVRTVASGGTVMDPQVIARLMARSTARGTTADLSPRELDVLRLMA
                     EGRSNAAVMAELHISESAVAKHTAAIFGKLRIDNTPDANRRVLAVLAYLKR"
     tRNA            complement(19883..19959)
                     /anticodon=(pos:complement(66351..66353),aa:Ala,seq:cgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CG736_RS19045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CG736_18985"
                     /product="tRNA-Ala"
     gene            complement(19883..19959)
                     /locus_tag="CG736_RS19045"
                     /old_locus_tag="CG736_18985"
     gene            complement(20107..21099)
                     /gene="glpR"
                     /locus_tag="CG736_RS19050"
                     /old_locus_tag="CG736_18990"
     CDS             complement(20107..21099)
                     /GO_component="GO:1990586 - divisome complex [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="glpR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142937.1"
                     /locus_tag="CG736_RS19050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18990"
                     /product="gephyrin-like molybdotransferase receptor GlpR"
                     /protein_id="WP_157815637.1"
                     /transl_table=11
                     /translation="MSSSGLIYAVIVGAWAAYLVPMWLRRQDELNESRPTERFSTAIRL
                     LAGRSAMERRAARALGEQTADQQHPAGEPDGAPVDPADVPTRPAAAGPAEPVVPAEPVV
                     PAEPDPVAEPGADRAGKRERDRGEQDERRSAERRARLLARRRRMVTLLFLAFALGAVVA
                     AVAGFAFLWVPAVPGILLTLYIGHLRRLERQRYEVKFDRVRAAQAAERLRERERARAAE
                     PATAPHAADVATEPATPASVLADATEHEEWVDGVRARAAAGPDSWEPVPVPLPTYVTAP
                     VAPRVTRGLDLSAPGTWDSGRPVTPLFDQYGEPGQQSAPEYRPPRAANE"
     misc_feature    complement(21169..21183)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.92"
                     /tool="antismash"
     misc_feature    21173..21188
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.27"
                     /tool="antismash"
     misc_feature    21181..21195
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.67"
                     /tool="antismash"
     misc_feature    complement(21242..21258)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    21246..21259
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.95"
                     /tool="antismash"
     misc_feature    complement(21246..21260)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.62"
                     /tool="antismash"
     misc_feature    complement(21247..21260)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    21248..21261
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.15"
                     /tool="antismash"
     misc_feature    complement(21251..21266)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.5"
                     /tool="antismash"
     misc_feature    21252..21265
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(21263..21889)
                     /locus_tag="CG736_RS19055"
                     /old_locus_tag="CG736_18995"
     CDS             complement(21263..21889)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846931.1"
                     /locus_tag="CG736_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CG736_18995"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_043915715.1"
                     /transl_table=11
                     /translation="MNAGWPTELVEGDVVLRPIRRRDQAEWQEVSRRNRDWLRRWEATV
                     PPAPAGRAPLPRPTFRQMVRYLRGEAAAGRMLPFVVLYRGRLVGQLTVGGITWGSMCSA
                     NVGYWVDEAVAGRGIMPTAVALAVDHCFRDLALHRVEVCIRPENRPSRRVVEKLGFRAE
                     GMRPRYLHIDGDWRDHLVYALTADEAADGLLRRWHALRSGPSQGN"
ORIGIN
        1 cgggctggac gaccgtgatc gccgcctcgg ccgaggtgct gtcgaggaac aggtcgtccg
       61 cgctccagcc gacgccgatc cggtagttgc cgtacagcgg catggtggcg gggaagaccg
      121 cgttgccctg gtcgtcagtg gtgcgccgga cgtggtcccc gaaggagttg gactcgatcg
      181 tccggcctgc cagcggctgc cagccggcgg tcggcgagtt ccacagcagg gtggcgctgg
      241 tggagtcgac gacgcccttg tacggcacct tgcgggtgct cgggttcgcc acgatcttcg
      301 tcgcggtctt cttgatccgg atcgggaaga acttcgtctc cgactggtcg tagaagacgt
      361 gcttcgggtc gtagttgaac ttcgcgaaaa tggtgttctg gtactggtcg gtgaccggca
      421 gggtcgcgct gaaactgccg tcgtccgccg tggtgacccg ggtgtactcc gcgtacgagg
      481 tgacgtccac ggcgagaccg cccatcggga cgacctctcc ggtgcctggc agccggccca
      541 tcaggtggcc gccgatggtc acggtgcggt gctcgtagtc gaccgtggtg cggtccaccg
      601 tggcgtcgtc gaggttggtg gagacggagt aggcgaagta gccgacaccg gtggtgttca
      661 acgtgtcgcc gccttcgtcg gtggccgaga cgtccatgcg gtacgagccg agcgcaggca
      721 actggacccg gccgcggttg ctccagctgc cgctggtggt ggtgccgccg gtcagctcca
      781 ggttggtcag ggtggcgacg gtctgttgcg tgtccatcga gtagaggctg accttgacgt
      841 tgctgatcgc gctcggcgcc gagagctcga ccaccagctt gccgttgttc gtccagtcgt
      901 tgtgggcgga ctggacgatg atcccggcgc cgtccgccag ggcggccggc gctccggtca
      961 ggacgagcgc gcccgcgatc gcggcggcgg acactgccgc cagtgcacga cgtgatgcca
     1021 tgagaaatac cccccgggta atggtccttc gccaccgatc cgttgatcag ggcagccgga
     1081 agctaccagc gggcactgac cgcctcgacg gaacccccgg tcagctgggg tcggcgggct
     1141 cctcggtgcg gggggcggcc aggcgggagt gcttggcgct gtaggtgaag tagaggacgg
     1201 cggcgagggc cagggcgatc gcgaaggcga tgaaggtgtc gcggtgcagc ttggtgatca
     1261 ggtagacgca gaagccggcg ctgagcacgg gggtgaccgg gtagaacggg accttgaagc
     1321 cgcgcgggag gtcggggcgg gtgcggcgga gcacgacgat gccgacggac acggcggtga
     1381 acgccaccag ggtgcccatc gaggtcatgt cggccagcag cctgagcggg aagacggcgg
     1441 ccagcagggc gaccgcggcg ccgaccacga cggtgttcca gaccggggtg ccggtgcgcg
     1501 gggagacccg ggtgaagggg cggggcagca ggccgtcgcg gcccatcgcg tagaggatcc
     1561 gggtctggcc gtagatcacc accagggtga tggagaagat cgagacgatc gcgccgccgg
     1621 cgaacaccag ggcgggccag gactggccgg tgacgtcctg gaggatctgc gcgaggccgg
     1681 ccttctgtcc gtcgaactgc tgccagggct gggcgccgac cgcggtgacg gcgaccgcga
     1741 tgtacagcag ggtgaccacg ccgagcgaga tcaggatggc cagcggcatg gtgcggcgcg
     1801 gctcgcggac ctcctcgccg gcggtggaga cggcgtccag gccgatgaag gagaagaaga
     1861 tggtggaggc ggccgtctgc acgccgcccc agccgttggg ggcgaacggg gtgaagttgc
     1921 cggcgtggaa gccggtcagg ccgatggcca cgaagagcac caggatggcc agcttgatgg
     1981 tcaccatcac ggcgttgacc ttggcggact cgccgacgcc gcggatcagc agcacggtga
     2041 ccagggcgac cagcaccacg gcgggcaggt tgaagacgcc gttctcgccg ggcggggcgg
     2101 tgagcgccgc aggcaggtgc aggccgaacg ccaggtcggc gaactggtcg aggtactggc
     2161 cccaggtgac ggcgatcgcg gacgcggaga cgccgtactc catcagcagg cagacgccga
     2221 cgccgaacgc gaccagctcg cccatggtgg cgtacgcgta cgagtaggag gagccggcca
     2281 ccgggatggc ggaggcgagt tcggcgtagc agagcgcggt gaggccggcc gtgacggcgg
     2341 cgatcacgaa ggacaccacc acggccggcc cggccaccgg gacggaggtg gtgaggacga
     2401 agaagatgcc ggtgccgacg gtggcgccga tgccgatggc ggagagttgc cacagcccga
     2461 tggatcggcg caggtgtccg gctccggttc cgcccgcttc ggcgatcagg gtgtccacgg
     2521 gcttgcgccg cagcaggcgg gtggtgctca tcggtcgtcc ttctggtggg gatcaggcac
     2581 ggactgtatc aaatacgccg atatgcatag ttatgagatc ttggtcgcgg gtccggcggt
     2641 caccggtcga ggacggcctg catgacggcc ttggcgatcg gcgcggccag ccgtcccccg
     2701 gtgacgtcgg tggccgtgct gtcggccacc accaccgcga cggcgaccgg cggggtcgcg
     2761 gtggacccgg cggggcgggc ccaggcgatg aaccaggcgt acggggtgcc gctgttgtcg
     2821 acgccgtgct cggcggtgcc ggtcttgccg ccgacctcgg cgcccgggat ctgcgcgttg
     2881 cctccggtgc cgttgttcac cacgttcacc atcagccggc gcagctcggc ggcgacgccg
     2941 ggcccgaacg cctgccggta cagggcgggg cgcatcagct ggacctgggt gccgtcggcc
     3001 ttggtgagcc ggtccaccag ctgcggatgc atcacccgcc cgtcggcggc gaccccggcg
     3061 gcgaccatcg ccatcaccag cggggtggcg gcggtgttgt actggccgat cgaggacagc
     3121 gccagctgcg agctgttcat cctggtgtcg aagttggagc gggcggcccg caccgggacg
     3181 tcgagcttgg cgtcgtcgaa gccgaagttc ttcgccatcg cgaccatcgg gtcgaggccg
     3241 gtctgcacgc cgagccagcc cagcacgctg ttgcaggaca gcgtcatcgc ctcgtccagc
     3301 gacagcccct cccggtcgca ggcgctggtg tcgttgttga gcgtggtggt ggtgccgggc
     3361 atcacgtacg ggaagggcgc gccggtgggg gcctggatgt ccgtcaccgt gccgttggcc
     3421 agcgcggccg cggcggtgac caccttgaag gtcgagccgg gcgggtagat ctgccgcagc
     3481 gcccggttga gcatcggctg gtcggggtcg gcctgcagct tctcccaggc ggcctggtcg
     3541 gcggcgccgg cgccggcgat cgcgccgggg tcgtagctgg gggtggaggc cagcgcgagg
     3601 atccggccgg tggcgggttc gatcgcggcg acggcgccct gctggccgcc gagcccctgc
     3661 atggcggcgc gctgcacggc cgggtcgatg gtggtgacca cgtcgccgcc gggctgctgg
     3721 ttgcgggtga tggcgtccca gaccgcccag ccggtcagcc gggggtcggt gccggtgagc
     3781 aggtcgtcgt agacgccctc cagctgggtg ttgccgtaga tctgcgagga gtagccggtg
     3841 acggcggcgt acagcgggcc gtcggtgtag gtgcgctggt acgccaggcg gccgccggtc
     3901 gcgaccgagc cggtgacggg ctgaccggcg atcaggttgc cgcgcggctg cgcgtaccgc
     3961 tggatggtgg cgcgctggtt ggcgctgttg tggtccagct cctgcttctg gaagacctgc
     4021 acccgggtgg cctggacggc cagcaggatg atcagcagca tgcagaaggt ggcggcccgc
     4081 cggccggtgg tggagatgcc gggcaggccc tgcggcccgc cgttggcgcc ctcgggccgg
     4141 gtgaacctca cgccgcctcc ccggggtcgg gacgccgggc gaggtcgctc atccgcacca
     4201 gcagcgccac gatgatccag ttggtgacca ccgaggaccc gccctgcgcg atgaacggca
     4261 gcgtcatgcc ggtcagcggg atcaggtcga ggacgccgcc ggccaccacg aacacctgga
     4321 tcgcgaccag cgcggccagg ccgatggcga gcagccgtcc gaacgggtcg cgcagcgcga
     4381 tgccggtgcg aaagccgcgg gagaccaaca gcgcgtacag caggaacacc gcgagcaggc
     4441 cggtcaggcc gagttcctcg ccgatggtgg ccaggatgaa gtcggacttg gtggcgaagc
     4501 cgatcagcgc ggagtggccg aggcccaggc cggtgccgag ctggcctccc caggcgaacg
     4561 cgaacagcga ctgggcgatc tggttggcgc cctgcccggc ccggatcgac gccagcgggt
     4621 gcagccagtc ggtgacccgg ctgtgcacgt gcggcgacag ccagcccacc ccgactgcgg
     4681 cgacggccga cagcagcagg ccgatgacga tccatccggt gcgggcggtg gccacgtaca
     4741 gcatcaccac gaacaggccg aagaacagca gcgaggtgcc gaggtcggtc tccagcacca
     4801 gcacgccgac gaacgccgcc cagatcagca gcaccggccc gagcacccgg ccgagcggca
     4861 gctggaacca cagcacccga cggccggtca gggcgagcgc gtcccggtgc cgcgccaggt
     4921 aggcggcgaa gaagatcgcc agcaggacct tggcgaactc gccgggctgg aaggacaacg
     4981 ggcccagcgt gatccagatc cgcgagccgt acaccggcgg gaagaacacc ggcagcacca
     5041 gcaggacgag ggccacgaac gccccgacgt acgcgtagcg ctggagccgg cggtggtcgc
     5101 gcagcaggag cagcaccgcg atgaacaggc ccactccgag ggtggaccac aacagttggg
     5161 tgggggcggc ctcgtggtgc ggggtgttgc ggtccagccg gtagatgacg accagtccga
     5221 tgccgttcag cagcaccgcg atcggcagca gcagcgggtc cgcccacttc gcccgccagc
     5281 gcaccgcgcc gtgcgcgagc agcgccagga cccctaacgc ggcgccgtac tgggcggcgt
     5341 ccggcggcgc cttgccgtcg atgtcgacgc ccacctcgac gtagccgaac acggccagcc
     5401 ccaccgcggc caccaccagc accagttcgg tccaccgccg gggccgccgg gcgccgggcg
     5461 tccaggccgc cgcacgggtc gcggagtcag tggccaccag ccgtcctccc gtcctcgccg
     5521 gcccgatggg gcagggacgg cggggtgccg gccggcaccc cgcccagtac tgcctgaggg
     5581 ggcgtcagag cgtggacgcg gggttcgccg cccgggcgat ctcccgcagg tgctcctcct
     5641 cctcgtggct gagcgaggtc tgcagcagct cgccgccgaa ctgcgcgacc gccgggatca
     5701 ccttgtcctg ggtggcggtg cgcaccagcg cgaacaccgc ggcggagccc ggggccagct
     5761 tctcgccgac cttccgcatg aagtcgtcgt ccacgccggt gtcggtggag gcgccgacgg
     5821 ccgcgccggt cgcgccgccg atcgccgcgc cgatcaccgg catcaggaac agcaggccga
     5881 tcacgccgcc ccacagcgcg ccggaggccg cgcccagacc ggtgttggag accgcctggt
     5941 ggagcttgat cttcccgtcc tcgcggcgct cgaccaccac gatgtcctcc aggtcgatca
     6001 gccgctgctt ctgaaggccg atcagctcgt cccggacctt ctgcgcggtg gcgacatcgg
     6061 ggtaggcgat cgcaaacagg ttgctcacgg cgggggttcc ttccagcagg gcttcgggca
     6121 cgtcccccag caccctagcc aggattcgcc atatttattc ccatctcctg cggtgtgtcc
     6181 ggttccccgc cgctcactcc ccgcggcgca ccgcgaccgc caccgccgcc cacccggccg
     6241 cccccgccag cagggccgcg cccggcagcg tccaccacgg cacggccgtc gcgccgtgcc
     6301 gcgaacccag caccagcgcc cgcaccaccg cgttcgccgg cgaccccggc agcagcagca
     6361 ccagcaccat cgcgcccagc cccagcggca ccgcgtactg cgcgcccgtc accaccggac
     6421 ggttgcacac cgcgcccacc gccgcgcccg tcagcacgca caccacggtg gccgacaggc
     6481 cggccgccac cgccccgccg ccaccgccgc tgcccaccag cagcaccccg gccaggcccg
     6541 ccacgcccag ggccagcccg gccagcgcgg ccgccaccag cgccgacagg tgcacccgcc
     6601 gccagcccgc ggccgccacc aggcaggccc gggactgcgc gggctccgcg gtcaccgccg
     6661 cccgcaccag ccagcccgtc accggcacca gcaggcccgc cgagaacgcc gccgccgaca
     6721 gcgcgtcgtc gccgccggac accccgagac ccatcagcac caggtacacc agcccgggcg
     6781 gcagccagcg ctgcgagcgc agcagcagtt cgaggtggta gcgcgtcagc gtccgcaccg
     6841 tcatgacgcc tcctcctgga cggacctgat gtgcaccggc gggtgcgcgg ccagcagtcg
     6901 gcgcagcagc gcgtcggagt gcgcggccgg cacgtccagc cgggtggcgc cgtcggccag
     6961 cggcttgcgc tcgggccggc ccggcagcca ctcggggagc gtctcggcct cgaccaccag
     7021 cgccgtgcgc gggccgtcgc cgtcggcggc cggcagcggg acctcgtgca gcgtgccgcc
     7081 gtcgacccgg tggacggcgg tggtcaggcc cgccagccgg gtcgggtcgt ggtcgacgaa
     7141 caccaccagg gcgcctgccg cggcgcgttc ggcgaccgcg ccgtcgagtt cgccgcgggc
     7201 ggcctggtcg agccccgtcc acgcctcgtc cagcagcagc aactcggcct cggcgagcag
     7261 cgcctgggcc accgcgacct tctggcaggt gcccttggag agccgcccga tcggggtgcc
     7321 cgcgtacccg gtgatgccga accgctccag ccagtggtcg gcccgccgcc gcgcctcccc
     7381 ggcagccagg ccgcggatcc ggcccaggtg gcacaggtag tcgcggacgt cgaacggcag
     7441 cgcgggcggg aaccgctccg ggacgtacgc ccggccgtcc ggcgcctcga ccgttccccg
     7501 ctcggcgcgt tcgatcccgg cgagcagctt cagcagcgtc gacttgccgc tgccgttggc
     7561 cccctcgatc cgcaccaggc cgcccggacg gagcgtcagt tcgacctccc gcagcaccca
     7621 cggacccccg cgtccgtagc gtttcccgac gcccgccaga cgcaccgtca tgcgctctcc
     7681 ccgcctgctc cgtcgaccag ttcagggtac gtcgcgctca ccacccgcat tgggcgattg
     7741 gaactgacgg tccctaggat gcggcagtga tcacccatac caagaaacga cggacggccc
     7801 gcggagccgc cctgctcggg gcgctgacaa tagtcgccgg caccgtgctc ggcacgctgc
     7861 ccgcgcacgc cgacgagccc ggggcaccgc ccgccgcgac cgaagcgccc aaggtcgacc
     7921 tcatcttgga cgggtcgggg tcgatgcgga ccgccgacat ccagggcaag agccggatcg
     7981 cggtcgccca gcagtccatc aacgaggtca tcgacgcgct gcccgccgag accgagttcg
     8041 gcctgcgcac cctcggcgcg acctacccgg gcaacgacca gaaggagggc tgcaaggaca
     8101 ccaagcagct cttcccggtc ggcaggacca acaaggtcga ggccaagacc gccgtcgcca
     8161 ccgtccgccc gaccggctgg accccgatcg gcgtggcgct gcgcgccgcc gcccaggacc
     8221 tcggcaccgg cccgaccacc cgccggatcg tgctgatcac cgacggcgag gacacctgcg
     8281 ccccgccgga cccgtgcgac gtggcccgcg aactcgccag ccagggcatc cacctggtga
     8341 tcgacaccct cggcctggcg cacgacgaca agacccgcca gcagctgctg tgcatcgcca
     8401 acgcgaccgg cggcaccttc accgacgtcc gcagccagga ccagctgacc cagcgcgtca
     8461 agcagatcgt cacccgggcc caggacaccc acaccgtcac ccccgcgaag gtgaccggcg
     8521 ccgagcagtg cagcagcgcg ccgatcctga cccccggcgt gtacagcgac cgcgagaagt
     8581 tctccgagca ccgcgtctac cgggtgccgg tgaaggccgg ccaggaactg cgcgcctcgg
     8641 tcagcgtcac ccccgaccgg gccgtcgccc gtgactacgg ggtcctgctg caggccaccg
     8701 acagcagcgg ccaggaactg gtccgcggca gcgacgcggg ctccggccgc accgacgtgg
     8761 cgtccaccgg cgtccgctgg tccgcgccgg gcaccgagtc cgccaccccc tcgccgacct
     8821 ccggcgccgc ggcgagcacc gaccgcaccg tctgcctgat cgtcagcaac tccttcgccg
     8881 gccaggccgg cgtccaggcc gacgccggcc tgccgctgga gctgaccgtc gacgtcgccg
     8941 ccgcctcccc cgcgcccgac ggccccgcga tgggcctggg ccgcggctgg atcctgctcg
     9001 gtgtgctcac cctggccggc ctgctcgccg gtctgatctt cggctggctg gcacgctggc
     9061 ggatcgccgt ctggcgggag aactgacgat gcgcaagctc ttcgccctcg cggccccggc
     9121 cgccgcgctc accggcctgc tcctgctggc cccgaccgcg acggcggcct cgccgtcgcc
     9181 gtccgcgagc ggcaccgcca agccggtgct caactcggtc ggcaccagct tcctcaccgc
     9241 caccacgctg gccgccggcc aggacgcgga cgtccccgtc tccaccggtg actacctgta
     9301 ctgggcgttc ccggcctccg agggccagac cgccaccgtc gaggtcaagg tcaccctccc
     9361 ggacgccgcc gaccggcacg gcccgcagac ctggaccgtc gaactcttcg acggcctgcg
     9421 gcgccgccag gcctgcacct ccggcccgca gaacggcacc gccgcggaca gcgccaccac
     9481 cgtggccctc agctgcacgc tccgccagat ccgctcctgg gccgagccct ggtccggcga
     9541 cccgctgccc ggcacctact acatccggct ctccaccagc gacatcccgc agcaggacct
     9601 cggcctcgcc tcccaggtcc acgtgcacgt cgccgccaag ggcggcgtca acgacgccca
     9661 gcccgagggc ggttcgctca aggccccgct ggtgccgccg gtcaacgccg gatccaccgc
     9721 gagcggctcc gccgcgaccc cggcccccag ttcgagcgcc gcctacgcgg ccgcccccgt
     9781 cgccgaagag acccactggt actcggatct cttctccggc tggaacaccc gctggtggtg
     9841 gaccgtcgcc ggcggcatcc tcgccgccct cgccggcgtc ctcggctaca ccctcacccg
     9901 ccacccgcgc gggcaccggc cgcaccacca tcacccgcac ctgtccgaat agggcttgca
     9961 accaggggcg cgtgggggta tcccacgcgc ccctgtccgt tcacgccctg agctctgcca
    10021 ggatccgcat cgccgacatc cccagttccg ccgtcaccgg gacctccggg gcgaagtggc
    10081 gcttgagcac gtcctccgag taccgccggc actgctggtg ccagtggagg acggcggcca
    10141 tccagtcctc cagctcgtgg acgtacccgt cgagcgcctc cgacgcctcg ccgtcgatgg
    10201 cgaagtcctg cttcagcagc ggcagttctc cctgcacgac gtgctggaac tggctcaggc
    10261 gggagcccat caggtcggcg acgatgtcca cggcgacggg gtagtcgcag gagaagaagt
    10321 tctccaccac ccggaccagg ttgtggacct cgccctcgta ctcgatctcc ttctggtacg
    10381 agtgcaggtc gttgaccagg caggcgtagt ccgccgcgga gttctcgatc gcccgcatgg
    10441 tgccgctccg gtacacctcg tcggggatgg tctcgccgcg accgagccgg gacaggctca
    10501 tcgtcaggtc ggagccgaag gtggcgcgtc gcatctcgat gtagtcgacg gggtcgggga
    10561 tccggttctg cgcgccgttg gcgagctccc agagccagct gtcgatcatg tcgccgacgg
    10621 ccttgcggaa cttggcccgg gcggcggtgg agaagggcac gatggtgcgc tgccagaggt
    10681 cggcgaggcc ggcttcgagg gcgttgcgcg gctcgaaggg gaggctgccg tcgagtgtca
    10741 tcagcgcgta cagccgctcg ttggcgagct tcgcgccggc caggtcgcgg ggggcgccga
    10801 agaccggggg gtagtagtcg tcggcgtagg tgccccaggt cagccaggcc gagctgaggt
    10861 cgagttcggc ggcggtgccg tcggggtcga tgccggcggc gcagagcggg aagtcgtagt
    10921 cgcggagctt ctgttcggtc cagatgtcgg aggcggggac gccgggttcc gggtcgagca
    10981 ggccgaactc gtgggaccag cggacgacgt actcccggga agcgtccacg tgcgggttga
    11041 tcgtgacggc gtacggcatc gggaaatcgg gcatcaacga cggcccgacc ctgcggtgcg
    11101 ggacgtgcgc gaagctgcgc aggccgcgga tgcccgccgc gaggcggatg ttggcggcgg
    11161 aggtgccgag gcccttgggg ccgaaggtgg gggcggccgc gccgccgccg ttcatgtagc
    11221 ggctggagcg catgtgccat tcgtggccgc cggactgcca gtcctgcatg cccttgacgt
    11281 acgccaggac gcgggcgatc tcctccgggt cgagcgcgtg ctcggcgaac aggccgggca
    11341 gttcggtgag cgcggtgttc tcgaactgct ggaggcggga ggtcagcagg tcgttgaccg
    11401 cgtccgcggc ctcctgggtg gagcagccga ggaaggtctc caacaccagg acgccgttgg
    11461 agagttcgcc ctcctcctgg atctcgcgct cgtacgagaa caggtcgttg cgcaggtgga
    11521 cgccgtcgga gaaggcgtcg cgcagcaccc gcagcggccg ggagtacgcg accgactcgg
    11581 gcacctcggc gtacgcggcg tactcgatca ggccggccga ccagggggcg ccgccgacct
    11641 tgcggcgcat ctcgatgtac tcgacggggt tggagacccg accctcgttg atgttggaga
    11701 gctcccacag ggactcgttc agcaggtgcc gggtggactc ggcgaaccgg gaccgccagt
    11761 cggcggacat gtgcgggacg gtgcgctgcc acaggtccgc caggcccgcc tcgaccgggt
    11821 tggtgggatc ggggaacccg tcggcgaggt ccatcggcat gaaggcgggc aggcggtcca
    11881 ggtaggcctt gccgccctcg cggtcgaggg tgcgcttgaa gatctccagg aagtggtcgt
    11941 cgaagaagaa gacccaggtg taccagtcgg tgacgaggtc gagcgcctcg ctgtcgcagt
    12001 cggggtgggt gtaggagcag agcagcgcgt agtcgtgcga gtcgagatcg tgctcctccc
    12061 agatgcccga tccctccagc atgccgaagt cgcgtgccca ctccttggtg tgcacccgtg
    12121 ccttctcgta gtgcgggttg atgcgcgccg ggtacggcac gtagaagtcc ggcagttcga
    12181 acggctgagc cactgggtcc cgcccctttt cgacgactga agatcggcgc gatgcctaac
    12241 gagccttccg accctcggtc accggaaccc cactccgtag cccacacgtc acaatccact
    12301 cgaacgagtg aaccgcgccg gtgtcgtacc ccttcggcag actgtcaccg tcctgccccc
    12361 gcaccgagga gcccgcacat ggcgttcacc gacgagacct ggcgcctggt gcacggcgag
    12421 gacctggtcg gcgagatccg catcgacgac gccgacttcc cctggctgca cggcgagttc
    12481 acccccggcc cgggctggcc ggggttcgcg cccaggttcg ccgagtgccg cgaactggcc
    12541 gaggccgagg agtgggacgc ctggggtcag gtgcacctga ggctggagca ggaactcacg
    12601 ctgcacgccc cggagggccc gatggcggag ttcctgctgc acatcgagcc gccccgggcc
    12661 tggttccgct tcagcgagga gccgttcgag gacgactgat cgtccgtcag ccggcctgcg
    12721 gccggaagac ccggacctcc gccgtgccgc tgctccagtc gacctgccag ccgcggcggg
    12781 cggccaggac ggcgaggccg tcgaggccga tgccccggta gtagcgccgg cggatcgtcg
    12841 tcctgggcac cagctcgtcg cccttgaact tgtaccggta cttgttggcg ttgaactcct
    12901 ggttcctccg cacggtggcc agtccccgct cgatcccgcg gtccagcgcc cgcccggccc
    12961 aggcctccca ctcctcgcgg gtgccctgcc gctccaggcg gtaacggctg ggcgtgagaa
    13021 cgaacttggc cacgcccggc tcggccgtgc cgtcgaacgc caccgagttg tccaggaagt
    13081 cccagacgat ccggaacggc agccagaacc actgcaggcc gaactggagc cacagcccga
    13141 gcacggagcg acgtggcagc gggccggtgt tcaggccggg cggggccggt gggtgccagg
    13201 tgctcatccg aacgcctccg tgatcttcgc ctggtccggc ccgggcgggg cggtcgcggg
    13261 ctgtgtgccg ggccggtcgt acaccacggt ctcgaccagg cccgcgagca tcgtcacgta
    13321 ctcggggaag tcgatcagca tgggcgtgct gatggtcatg gtgaccaggg tgtccgcacc
    13381 ctgcaccggg atgtacgcgg acgcctgggc cagttcgagc ttcgccttgt tcccgaactc
    13441 gtcgtcgacc tcggcgagcg acccggcgac ggcgaccacc accgggccga ccggggcggg
    13501 cacccggaac acctcgttgg cggggtcgag ggagagcatg tcctggatcg cggcggcgac
    13561 cgtgtcggcg tccgcggtgt cggcctggtc ggcctggatg accagggtgg cgacggtgac
    13621 ccggtcgtcc tcggtgccgg ccagcaggaa gccggagtag accgcgccct cctccccggc
    13681 ggtggcggcg atgtcgctgt accaggaggc gacggtgctg cgctggaact cggtgccgcc
    13741 gcaccagatc tcggcggcca cttcggcgag gtgcgcctcc cgctcctgct cgggcagttc
    13801 gacgccgagc gagtggaact gggccggcac cacccaccgg atgtcgagcg cgtcgtccgg
    13861 gaggatgtcg gccgggagac tctcggccgg gccgttctgc ggggtcgtca cgaggtcact
    13921 tcctggtaca gggtgggcgc gtgcatgatc aggccgctgc ccttcatgcc gatctgggtg
    13981 ccgcgcgacc accaggactc gaccgggagc gagaagacct tctggccgtc ctccccgagc
    14041 gagccgatgc cgggcagctt cttcagcggg gtcttggtga acagcggagt gagcaccttg
    14101 ttgtgcagca ggccgccctc caggtgggtg gccttgatgg cctgcccggc ttccatcagc
    14161 ttcgctccgc cggccgccag gccctcgccc ttggcgatgg ccgtgacgcc cttggcggcg
    14221 cccccgatgc ccttggcggc accgcccacg aacggcacca cgccgacgcc gtccagcgcg
    14281 atggtggtcc aactgacgtc cgcgccgccg agtttggcca tcccgtgcgc accgagcgcg
    14341 accgcggacg cgccgccggc cgcgacgccg agggcggcgg acagcggcgg gcaccacagg
    14401 gtggcgaggg ccgcgatgcc gagcaccgcc gagacgccgc ccgcgatgtc gccgatcttc
    14461 ttcagcaggt cggcgtgctt ggtggcccag tccttgatct tcttgccgac gctcttgaag
    14521 ccgttgccga tcttctccca ggcgctgatc tcgggagcgt tctggttggc ccggcggagc
    14581 gccttcgcgg tccggtcggc gtcgtcctgg tggtgctcgt gcagttcctt ggcctgcttg
    14641 acgatcgctt ccagctcgtc cttgatggcc cggagctcgc ggttggcgtc ctccaactgg
    14701 cgttcggcgg tgctgtattc ggcgctcgcc gcgtcgatcc ggcgctgggc gtcggcgagc
    14761 gcggcgtcgt cgtcgaaccg cttgccgatc agcgcgaacg ccggggagtc ggccgccagg
    14821 tcgaaccgtt cgacggcgtt ctgcttgacg ttctccgcgt tctccatccg gcgcttggcc
    14881 tcggccgcct cggcctcgta gcgccgggcc accccctggt acgagaccag ctggttcttc
    14941 cagctgtcga gctgaccgga ggcctgccgc atcgcgtcga cgctgtcggc caggtagcgc
    15001 ggcagttcgc cgaccttgcc ggcgaacgcc ttggcggcgt cgccctccca gacgctgccg
    15061 ccctgtccga cggcgaccag ggtgcggtgg gcgctctcca tcgcgacgga cgcccggttg
    15121 agcttgtcga ccaggccgtc gacgttctcg gggctgccgg gggccgggtc gaagcccagg
    15181 gtggggaagt cggccttgct gctcacgcgg ccgctccggt gaacatgtcc cggatcgcct
    15241 ggtcggtctc cgagtagccc ttgcaggtct cctggagctt gccctccagg gcctcgacgc
    15301 cctgcgagat ccgggtgatg gcgtcctgcc agctgtcgtt gaagtcgtcg caggcgtggt
    15361 ccaggttctt gctcccggtg gtcttcggac cggtgtcctt catcgcgcgg agcgcctcgc
    15421 gcatgtcctg ctgactgctc ttcagctgct tcaccagccg gtcgagttcg ctcacttcga
    15481 cccggaagta ggcccccatg ctgcgctgat cccctctggg cccgagcagt gcgacgcgac
    15541 gcccactccc gtggccgtgc gcacattccg caagggcgcc tttgccgttc cttcacatga
    15601 ggcgtccgag cggtcgacgc ccccgcgtcc gcgccggacc gacctgggta ttcgtggaat
    15661 gcgaggcccc ggcgcacggt ggcggtcttt gccgaactgt ggttcggcgc tcgaacacca
    15721 aagcgcagat taccttccgc ctgcgaaggg tcgacccgcc ggggcgtcgg cgcagggcgt
    15781 cggggcgggc tgtcggagcg ggatgtcagg gcagtgcgag cgcgagcggc tgcgcggggc
    15841 tgcgggggtc gaggcggtag ctccagtcgg cgggcaccag caggcactgg gaggcgcgca
    15901 ggcgcagcgt gctgcggcgg gcggcggagc ccgggggcgg gctcaggtgg atctcggcgg
    15961 cggcgcgccg ctgcaccagc agcaccgcgg accggccgcg ctgccacggc ccggcgggcc
    16021 gctcggggac gggccggacg gggcgggcca gttcgcgctc cagcgcggcg gccagtgcgc
    16081 cggccgagcc gtccggcgcc ggctcctgtt cgctccacag cagcgccggg gcggagcggg
    16141 cggcggcgcc ccgcaggaag gccgccaact ccgcgacctg gccgcccggt tccggggacg
    16201 gccggtcctc cccctcgtac cactgcacgt gtgccacccc tccggaccgg gcgccggacc
    16261 gtctcgggca ccgagaacca tcctgggcag tggcggatct gacgaccagt cacgagatcg
    16321 cgcgacaccg gaccccgcgt cgccgcgccg caagggtcgt ggcctttgct ccggttcggg
    16381 ccggttcgcc ccctggtcac cttgctgcca gcgcagttga tgaggtgggc gcacggtggt
    16441 cccggggcgg cccgcccgga catgctgggt gcaggccgat caacgccggg cgggccgccc
    16501 ggcaggcccg ctccccacac cccgcaaccg ccctcggagg cctccatgaa gcgcgccctc
    16561 gccctcgtcg ccgtcaccgc cgccgccctg ttcgcggccg ctccgctggc ctccgccacc
    16621 accgtgcccg ccccggccgg atccgccacg cagctgtcgg tcgggctgcc gaacaccccg
    16681 ctcgacggcg acacctcgtg gggcggcgcc tgcgagacgc ccctctgcaa gccctggtcc
    16741 tgaccgcccc caccacctcg ccccgggagt cctccatgca caccatcggc atcgcgttca
    16801 gccgccgcga gctccaggtc ctgcacctgg tcggcgaggg cgccagctac gcgacgatcg
    16861 cccgccggct cggtctcagc ccgcacaccg tcgacaccta tctgcgccgg atccgcgcca
    16921 agtccggtgt cagctcacag gtccagctcg ccctgctggc ctcccgactg cccacgcagc
    16981 ccgcccaggc cgccgcctga gcgcaggggg tgcagctggg tacaccccgg ccgggcaggt
    17041 ggctgcaatg gcacggggcc gcccgcccgg gatcgtcatg ggtgacacga cgatcccgac
    17101 cgagaggcga actcccgtgc aagaacgacg acccggctgg ctcggccccg ccgcgctctt
    17161 cctgaccgcg accgtcatgg cctccggcct gatgctggcc ctccagccgc tcaccgggct
    17221 gcccggcgag gtcctcgaac tggtgcagtt cggcccggcg gtgggcgtgg ccgtggtcgc
    17281 cctggtgcgg ccgtcgcagg tgcggggcct gctgacggcc ggcgggccgc gcggcccgcg
    17341 cggggcggtg ctgctgagcg ccctggcgat catcgcggtg gcggtggccg gttcgctgct
    17401 gctgcacggc agcgtcccgg tgcgcgaccc gaacgggctg gtcgccccgt tctgggtggt
    17461 ggcggtggcc cagttcgtgg gcgcgtgcgg cgaggagatc ggctggcgct gcttcctcca
    17521 gccgctgctg cggaccaggt tcgggccgct cggctcgtcc gtggcggtcg gcctgctctg
    17581 gggctgctgg cacctgcaga tcttcgcggc ggccccggcg tacgcgatcg gcttcctggc
    17641 ggcgaccacc gccatgtcgg tgctgctggg cctggcctgg gagcggatcg gcgcccaccg
    17701 gctgctggtg gccggcggct tccacaccct ggtgaacctg ggcatgctgc tgttcctgga
    17761 cgaggagtcc ggcgcggtgg agccgatggt gctgttcggc gtcgccggcg tgctggtcgc
    17821 cctgccctgg gtcctggccg ccctgcgccc ggcccgcacg gataggctcg cgacgacatg
    17881 acggatcgac agaagcgttt ccgggggccg ctggtcgccc tcgtccgctg ccaactgctc
    17941 tcgctggcct ccctggtgac gtcgctgcgg tcgctcgcgg tgctcggcgc gctggcgctg
    18001 ctgccggtcg gcgcgggtct gccgctgctg ccgcccgccg cccgcatgct gcgccgcggc
    18061 agcgacctcg aacgcgaccg cacggcccgc tggacgggca ccgtgatcga cgcgcccgaa
    18121 ccgctgccca ccgcgccgac cgtcaccggc cggggggcgg cggtgctcgg ctcgaccgcg
    18181 ttctggcgcg acgtggcctg gtgctgcttc ggcccgtgga gcaccggcct gctggtctcc
    18241 gtcccgccga cgctggtcgg ctacggcctg ttcggcgccg tggcgcagcc gttcctgtgg
    18301 ccgtacctcg gcccgggcaa ctggtacgcc ttcataccgg tcgagtccac caccaccgcg
    18361 atcgccgccg ccgccctcgg cctgggtttc gtcgcggcgg gcctgtggct gtccgtcccg
    18421 gcgctggtcc gctacggcga gtggaccggg cggctgctcg gcgacccgta cgcggcccgg
    18481 ctggagcggc ggatcggcca gctgacggac agccgggccg acgcgctgga cacccaggcc
    18541 gccgagctgc gccggatcga acgcgacctg cacgacggcg cgcaggcccg gctggtcgcc
    18601 ctcggcctga ccctcgacca ggccgaccgg ctggtggaca gcgacccgac cgccgcccgc
    18661 cgcctgctcg gcgaggtccg ggccagctcc gagcgggccc tgcaggaact gcgcgacctg
    18721 gtccacggca tcctgccgcc ggtgctcgcc gaccgcggcc tgcccgacgc cgtccgctcg
    18781 ctcgccctgg acgccttcct ggacgtcgag gtggacgccg agctgcccgg ccggctgccc
    18841 gccgccgtcg agggcgccgc ctacttcgcg atcgccgaac tgctcgccaa cgcgggcaag
    18901 cactccggcg gcagcaccgt acggatccgg ctgcgctgcg ccgacggcct gctgcgcgcc
    18961 accgtcaccg acgacggccg gggcggcgcc gacccggccc gcggctccgg cctggccggg
    19021 gtgcgccgcc gactggccgc cttcgacggc accctcgccc tggtcagccc gccgggcgga
    19081 ccgaccaccg cgaccctgga gctcccgtgc gcgtcgtcct cgccgaagac ctcttcctcc
    19141 tccgtgacgg cctgagccgc actctcgccg aacacggttt cgatgtcgcc gccgccgtcg
    19201 aaaccggccc cgaactgctg cgcgccctgc gcgagttgcg gccggacgtg gccgtggtcg
    19261 acatccggct gccgcccacc cacaccgacg agggcctgca ggccgcgctg accgtccgcc
    19321 gcgaacgccc cgccctgccg gtgctggtgc tgtcccagta cgtcgagcag ctgtacgccc
    19381 aagagctgct cgccgacggg cacggcgcgg tcggctacct gctcaaggac cgggtcaccc
    19441 acaccgcgca gttcgtcgac gccgtccgca ccgtcgcctc cggaggcacc gtgatggacc
    19501 cgcaggtgat cgcccgcctg atggcccgct ccaccgcccg cggcaccacc gccgacctgt
    19561 cgccccgcga actcgacgtg ctgcgcctga tggccgaggg ccgctccaac gccgccgtga
    19621 tggccgaact gcacatcagc gagagcgcgg tggccaaaca caccgccgcg atcttcggca
    19681 agctccggat cgacaacacc cccgacgcca accgccgggt actggccgtc ctcgcctacc
    19741 tgaagcgctg accgccccgc cgccccggac cccggcccgc ccccggcggg ccgggtcctc
    19801 gcacacccgc gcccggcccg ttgacgggcc gtcgccccga acgcaagaag tcccgcccgg
    19861 atcacccgga cgggacttct gttggtggag ctgaggggat tcgaacccct gaccccctcg
    19921 atgcgaacga ggtgcgctac cggactgcgc cacagcccca acaagaagaa ctctatcacc
    19981 cctgaagagg tactcatgac catggtcgcg acggccggat gacaggacgt ccggaccgcc
    20041 ggcaccgcag cggggcggga gaacgcgaac gccccgcgcg ggtggcgggg cgttcggggg
    20101 tgcgggctac tcgttggcgg cgcggggcgg gcggtactcg ggggccgact gctggccggg
    20161 ctcgccgtac tggtcgaaca gcggggtgac ggggcggccc gagtcccagg tgccgggggc
    20221 ggagaggtcg aggccccggg tgacccgggg ggccacgggg gcggtgacgt aggtgggcag
    20281 cgggacgggg acgggctccc aggagtcggg gccggccgcg gcgcgggcgc ggacgccgtc
    20341 gacccactcc tcgtgctcgg tggcgtcggc gaggacgctg gccggggtcg cgggctcggt
    20401 cgccacgtcg gcggcatggg gggcggtcgc gggctcggcc gcccgggccc gctcgcgttc
    20461 ccgcagccgc tcggcggcct gcgcggcccg cacccggtcg aacttgacct cgtaacgctg
    20521 ccgttcgagc cggcgcaggt gtccgatgta aagagtgagg aggatgcctg gcacggccgg
    20581 cacccagagg aacgcgaaac cggccaccgc ggcgacgacc gcgccgagtg cgaaggcgag
    20641 gaagagcagg gtgaccatcc gccgccgtct ggccagcagc cgggcccgcc gttcggcgga
    20701 gcgccgctcg tcctgctcgc cccggtcccg ctcgcgcttc ccggcccggt ccgcgcccgg
    20761 ctcggcgacc gggtccggct ccgcgggcac gacgggttcc gcgggcacga cgggctccgc
    20821 cgggcccgcc gcggcgggcc tggtgggaac gtccgcgggg tcgacggggg ccccgtccgg
    20881 ctcaccggcg gggtgctgct ggtcggcggt ctgttcgccg agggctcggg ccgcgcgccg
    20941 ttccatggcc gatcgcccgg ccagcaggcg gatcgcggta ctgaagcgtt ccgtcggacg
    21001 cgactcgttg agctcgtcct gcctgcggag ccacatcggc accagatagg cggcccaggc
    21061 ccctacgatg accgcgtaga taaggccgct gctgctcacg tttcacacgg tacgggcgcg
    21121 gggtaaggcg ctgcagcaat ttgggacggc gtgtcgtgcg atcaagctga ttctcagact
    21181 attttgccgg tatttgtgac ggctcgcccc ggccccggcg acccgccgat gccatatcga
    21241 tatctgcttt tcgaacaaat attcaattcc cctgtgacgg accgctcctg agggcgtgcc
    21301 agcgccgcag cagaccgtcg gcggcctcgt cggcggtcag cgcgtagacc aggtggtcgc
    21361 gccagtcgcc gtcgatgtgc agatagcggg ggcgcattcc ctccgcgcgg aagccgagtt
    21421 tctccaccac ccggcggctg ggtcggttct cggggcggat gcacacctcg acccggtgca
    21481 gcgccaggtc acggaagcag tggtcgacgg cgagcgcgac ggcggtcggc atgatgccgc
    21541 ggccggccac cgcctcgtcc acccagtagc cgacgttggc ggagcacatc gagccccagg
    21601 tgatcccgcc gacggtcagc tggccgacca ggcggccgcg gtagagcacc acgaagggca
    21661 gcatccggcc ggccgcggcc tccccgcgca ggtagcggac catctgccgg aaggtgggcc
    21721 ggggcagcgg ggcgcggccg gccggggcgg gcgggacggt ggcctcccag cggcgcagcc
    21781 agtcccggtt gcgccggctg acctcctgcc actcggcctg gtcgcggcgg cggatgggcc
    21841 gcagcacgac gtccccctcg accagctcgg tcggccaccc cgcgttcagt gcgcaccgcc
    21901 cgcgggtcgc ggatggtcgc cgccggccaa ctggtcgacg gcgtgcggca acagcggggc
    21961 gaggacggcg aggccgtccc ggacgccgcc ggtggagccg ggcaggttga cgatcagggt
    22021 gcgtccggcg cagcccgcca ggccgcggga gagcgccgcg gtcggcacct tctcgcggcc
    22081 gtacgcccgg atcgcctcgg ggattccggg gagctgccgg tcgatcaccc gggcggtcat
    22141 ctcgggcgtg aggtcctgcg gggagatgcc ggtgccgccg gtggtgagca cca
//
