Select genomic region:
Overview
1.1
3.1
4.1
4.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_PCGR01000001.1 (Chryseomicrobium excrementi)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | terpene-precursor | 312,586 | 333,470 |  |

NZ_PCGR01000002.1 (Chryseomicrobium excrementi)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 3.1 | terpene | 17,071 | 37,874 |

NZ_PCGR01000003.1 (Chryseomicrobium excrementi)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 4.1 | lanthipeptide-class-ii | 105,364 | 133,255 | Medium | staphylococcin C55 α/staphylococcin C55 β | ribosomal:RiPP:Lanthipeptide
Region 4.2 | terpene | 271,934 | 292,767 | Medium | carotenoid | terpene

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | terpene-precursor | 312,586 | 333,470 |  |
Region 3.1 | terpene | 17,071 | 37,874 |
Region 4.1 | lanthipeptide-class-ii | 105,364 | 133,255 | Medium | staphylococcin C55 α/staphylococcin C55 β | ribosomal:RiPP:Lanthipeptide
Region 4.2 | terpene | 271,934 | 292,767 | Medium | carotenoid | terpene

No secondary metabolite regions were found in these records:
  NZ_PCGR01000010.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000004.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000005.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000006.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000007.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000008.1 (Chryseomicrobium excrementi)
  NZ_PCGR01000009.1 (Chryseomicrobium excrementi)

Compact view
NZ_PCGR01000001.1 - Region 1 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 312,586 - 333,470 nt. (total: 20,885 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Transferases: carboxylase
CQS04_RS01635: acetyl-CoA carboxylase biotin carboxylase

smcogs
  SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Hydrolases: peptidase
CQS04_RS01620: methionine aminopeptidase

smcogs
  SMCOG1172: methionine aminopeptidase

Ligases: synthase synthetase
CQS04_RS01665: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

CQS04_RS01670: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs
  SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002283.2 |  | 0.49 | terpene | sodorifen | Serratia plymuthica
BGC0001361.3 |  | 0.49 | terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0000665.5 |  | 0.41 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0002284.3 |  | 0.40 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000668.5 |  | 0.40 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001594.3 |  | 0.39 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0000666.5 |  | 0.38 | terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0002398.2 |  | 0.38 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002283.2 |  | 0.49 | terpene | sodorifen | Serratia plymuthica
BGC0001361.3 |  | 0.49 | terpene | sodorifen | Serratia plymuthica 4Rx13
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0000665.5 |  | 0.41 | other (other), terpene | xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C | Streptomyces sp. HKI0576
BGC0002284.3 |  | 0.40 | other (other) | corynecin III, corynecin I, corynecin II | Rhodococcus sp. H-CA8f
BGC0000668.5 |  | 0.40 | other (other), terpene | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001594.3 |  | 0.39 | other (other) | fischerindole L | Fischerella muscicola UTEX 1829
BGC0000666.5 |  | 0.38 | terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0002398.2 |  | 0.38 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
CQS04_RS01665: PT_FPPS_like
Domain 1 (33 - 293): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  DMAPP, IPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.59 out of 27.78
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 24.46 out of 28.19
Confidence: strong
LexA variant 3
Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 25.67 out of 32.93
Confidence: medium
Additional weak hits (3):
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 20.68 out of 26.12
Confidence: weak
HypR
Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40
Confidence: weak
MatP
Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.31 out of 25.75
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
LexA variant 3 | Repressor of DNA damage response
ZuR variant 1 | Zinc-responsive repressor

NZ_PCGR01000002.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 17,071 - 37,874 nt. (total: 20,804 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: deacetylase hydrolase
CQS04_RS04655: amidohydrolase

smcogs
  SMCOG1244: amidohydrolase

CQS04_RS04725: acetylornithine deacetylase

smcogs
  SMCOG1247: acetylornithine deacetylase

Lyases: cyclase
CQS04_RS04680: diguanylate cyclase

smcogs
  SMCOG1025: diguanylate cyclase

Isomerases: racemase
CQS04_RS04670: mandelate racemase/muconate lactonizing enzyme

smcogs
  SMCOG1268: mandelate racemase/muconate lactonizing enzyme

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002343.3 |  | 0.34 | other (other), ribosomal | ammosester A, ammosester B, ammosester C, ammosamaic acid cogener | Streptomyces uncialis
BGC0000334.4 |  | 0.31 | NRPS | cyclosporin A | Tolypocladium inflatum NRRL 8044
BGC0002386.2 |  | 0.31 | NRPS, PKS | cyclo(n-Me-L-Leu-L-Val), cyclo(n-Me-L-Leu-L-Leu), cyclo(n-Me-L-Leu-L-Ile) | Sorangium cellulosum So0157-2
BGC0000938.5 |  | 0.31 | other (aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0001733.3 |  | 0.29 | ribosomal | PcpA | Pleurocapsa sp. PCC 7327
BGC0000651.5 |  | 0.28 | terpene | KS-505a | Streptomyces argenteolus
BGC0002026.3 |  | 0.27 | NRPS, PKS | thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2 | Jahnella sp. MSr9139
BGC0000367.5 |  | 0.27 | NRPS | gramicidin | Brevibacillus brevis NBRC 100599
BGC0002126.3 |  | 0.27 | NRPS | hypeptin | Lysobacter sp. K5869
BGC0002025.4 |  | 0.27 | NRPS, PKS | thaxteramide C | Jahnella sp. MSr9139

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002343.3 |  | 0.34 | other (other), ribosomal | ammosester A, ammosester B, ammosester C, ammosamaic acid cogener | Streptomyces uncialis
BGC0000334.4 |  | 0.31 | NRPS | cyclosporin A | Tolypocladium inflatum NRRL 8044
BGC0002386.2 |  | 0.31 | NRPS, PKS | cyclo(n-Me-L-Leu-L-Val), cyclo(n-Me-L-Leu-L-Leu), cyclo(n-Me-L-Leu-L-Ile) | Sorangium cellulosum So0157-2
BGC0000938.5 |  | 0.31 | other (aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0001733.3 |  | 0.29 | ribosomal | PcpA | Pleurocapsa sp. PCC 7327
BGC0000651.5 |  | 0.28 | terpene | KS-505a | Streptomyces argenteolus
BGC0002026.3 |  | 0.27 | NRPS, PKS | thaxteramide A1, thaxteramide A2, thaxteramide B1, thaxteramide B2 | Jahnella sp. MSr9139
BGC0000367.5 |  | 0.27 | NRPS | gramicidin | Brevibacillus brevis NBRC 100599
BGC0002126.3 |  | 0.27 | NRPS | hypeptin | Lysobacter sp. K5869
BGC0002025.4 |  | 0.27 | NRPS, PKS | thaxteramide C | Jahnella sp. MSr9139

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none
triterpene |  | squalene | C30 | acyclic | none
triterpene |  | PSPP | C30 | acyclic | PP
tetraterpene | C40 carotenoid | phytoene | C40 | acyclic | none
triterpene |  | hydroxysqualene | C30 | acyclic | OH

Genes with terpene domains:
CQS04_RS04685: PT_phytoene_like
Domain 1 (3 - 225): Prenyltransferase; Phytoene synthase like
Subtype: unknown

Reactions:
  FPP → diapophytoene
  FPP → squalene
  FPP → PSPP
  GGPP → phytoene
  PSPP → hydroxysqualene

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 27.81 out of 29.38
Confidence: strong
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.54 out of 29.38
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 26.44 out of 28.19
Confidence: strong
BldD
Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 20.41 out of 23.43
Confidence: medium
Additional weak hits (3):
ArgR
Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 17.65 out of 20.01
Confidence: weak
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.61 out of 32.74
Confidence: weak
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.31 out of 29.38
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate
GGPP | Geranylgeranyl diphosphate
PP | Diphosphate
PSPP | Presqualene diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
BldD | Development and antibiotic global regulator
FuR variant 1 | Ferric Uptake Regulator
ZuR variant 1 | Zinc-responsive repressor

NZ_PCGR01000003.1 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 105,364 - 133,255 nt. (total: 27,892 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
CQS04_RS09565: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

CQS04_RS09645: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs
  SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase
CQS04_RS09630: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

CQS04_RS09640: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.80 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.71 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.61 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0002276.2 |  | 0.54 | NRPS | choline | Aspergillus nidulans FGSC A4
BGC0000517.4 |  | 0.52 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.3 |  | 0.51 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001391.3 |  | 0.50 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000497.3 |  | 0.50 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.80 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.71 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.61 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0002276.2 |  | 0.54 | NRPS | choline | Aspergillus nidulans FGSC A4
BGC0000517.4 |  | 0.52 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.3 |  | 0.51 | ribosomal | SmbA, SmbB | Streptococcus mutans
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001391.3 |  | 0.50 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000497.3 |  | 0.50 | ribosomal | BHT-Aα, BHT-Aβ | Streptococcus ratti

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for CQS04_RS09630

CQS04_RS09620
Leader:
MKNELLKQEQVTWFEEVADQQFDDDVFGA
Core:
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dha L Dha D Y W G N N G N W Cys Dhb A Dhb H E Cys M Dha W Cys K

#### antiSMASH-DB 4.0 matches for CQS04_RS09620

100.0%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
93.3%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G N W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G W C T A T H E C M S W C K
1
C T T N T F S L S D Y W G N K G G W C T A T H E C M S W C K
30
with 104 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G N W C T A+H E C M S W C K
1
C S T N T F S L S D Y W G N N G N W C T A S H E C M S W C K
30
90.0%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G N W C T T H E C M+W C K
1
C T T N T F S L S D Y W G N K G N W C T L T H E C M N W C K
30
90.0%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N+G+W C T A T H E C+S W C K
1
C T T N T F S L S D Y W G N D G S W C T A T H E C L S W C K
30
86.7%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y W G N N G N W C T L S H E C M A W C K
30
86.7%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G W C T T H E C M S W C K
1
C S T N T F S L S D Y W G N R G Y W C T L T H E C M S W C K
30
86.7%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G C T T H E C M S W C K
1
C S T N T F S L S D Y W G N N G W L C T I T H E C M S W C K
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G W C T +H E C M S W C K
1
C S T N T F S L S D Y W G N K G G W C T I S H E C M S W C K
30
83.3%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y G N N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y M G N N G N W C T I S H E C M A W C K
30
83.3%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide
Lanthipeptides: BHL26_RS15350_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N+G+W C+ +H E C M S W C K
1
C T T N T F S L S D Y W G N D G S W C S L S H E C M S W C K
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y W G N R G N W C T L S H E C M A W C K
30

#### MIBiG 4.0 matches for CQS04_RS09620

66.7%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C
29
C T T N T F S L S+ G N N G W C T T E C C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
36.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F S L S D Y W G N N G N W C T A T H E C M S W C
29
+++S G N G +C T T E C M C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T A T H E C M S W C
29
C T + E C C
28
C T L S K E C Q P N C
38
CQS04_RS09625
Leader:
MHNKSIHENSEKELELGRYLESDMLALTDDEVAGG
Core:
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
Core with dehydrations:
A Dhb P Dhb I V I Dhb A I Dhb G Y I Dha A N Dha Cys P Dhb Dhb A Cys Dhb R A Cys

#### antiSMASH-DB 4.0 matches for CQS04_RS09625

100.0%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
82.1%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T I V I T A+T G Y I S N+C P T T+C T R A C
2
T P T I V I T A V T G Y I S T N T C P T T S C T R A C
28
63.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T +I +T A++G Y I S+N+C P T T A C T R A C
4
T V S I A L T A V S G Y I S S N T C P T T A C T R A C
30
with 101 more sequence matches
Only the first 10 are displayed here.
60.7%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
7
I T A I T G Y I S A N S C P T T A C T R A C
28
++ I T G Y I S+N+C P T T A C T R A C
5
L S V I T G Y I S S N T C P T T A C T R A C
26
60.7%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P I I ++G+I S N+C P+T A C T R A C
2
T P A I S I-L V S G F I S T N T C P S T A C T R A C
27
59.4%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
1
A T P-T I V I T A I T G Y I S A N S C P T T A C T R A C
28
A T P T V I A++ Y+S +C P T T A C T R A C
4
A T P A T P V I V A V S A Y V S D K T C P T T A C T R A C
32
57.6%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
1
A T P T I V I--T A I T G Y I S A N S C P T T A C T R A C
28
A T P +V A+T +I S A N+C P T T+C T R A C
4
A T P W L V K A S V A V T A F I S A N T C P T T S C T R A C
33
57.6%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
2
T P T I V-----I T A I T G Y I S A N S C P T T A C T R A C
28
T P T++ +T A++G Y I S+N+C P+T A C T R A C
2
T P T V L A T T G A L T A V S G Y I S S N T C P S T A C T R A C
33
57.1%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T I V I+ ++ Y+S N+C P T T+C T C
1
T P T I V I S V V S A Y V S T N T C P T T S C T D E C
27
54.8%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
A T P T I V I---T A I T G Y I S A N S C P T T A C T R A C
28
T P T I I A++G+I S +C P T+ C T R A C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
53.6%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T+V++ ++ +I S N+C P++A C T R A C
1
G T P T V V L S I V S A W I S N N T C P S S A C T R A C
28
53.6%
NZ_JALAPU010000003.1 and 7 others:
NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide
Lanthipeptides: MOD17_RS07925_lanthipeptide
7
I T A I T G Y I S A N S C P T T A C T R A C
28
++ +T Y I S+N+C P T T A C T R A C
5
L S V V T A Y I S S N T C P T T A C T R A C
26
53.3%
NZ_QGEE01000020.1 and 3 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide
Lanthipeptides: DKP74_RS06165_lanthipeptide
2
T P T I V I T A I--T G Y I S A N S C P T T A C T R A C
28
T P I +A+ +G++S+++C P T T A C T R A C
2
T P V I G Y S A V I V S G F V S S H T C P T T A C T R A C
30

#### MIBiG 4.0 matches for CQS04_RS09625

25.0%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
19
C P T T A C T R A C
28
C P T T C T C
17
C P T T K C T S K C
26
24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
14
I S A N S C P T T A C T R A C
28
+S A C P T T C T C
23
V S A A F C P T T K C T S R C
37

#### Lanthipeptide(s) for CQS04_RS09640

CQS04_RS09620
Leader:
MKNELLKQEQVTWFEEVADQQFDDDVFGA
Core:
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dha L Dha D Y W G N N G N W Cys Dhb A Dhb H E Cys M Dha W Cys K

#### antiSMASH-DB 4.0 matches for CQS04_RS09620

100.0%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
93.3%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G N W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G W C T A T H E C M S W C K
1
C T T N T F S L S D Y W G N K G G W C T A T H E C M S W C K
30
with 104 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G N W C T A+H E C M S W C K
1
C S T N T F S L S D Y W G N N G N W C T A S H E C M S W C K
30
90.0%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N G N W C T T H E C M+W C K
1
C T T N T F S L S D Y W G N K G N W C T L T H E C M N W C K
30
90.0%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N+G+W C T A T H E C+S W C K
1
C T T N T F S L S D Y W G N D G S W C T A T H E C L S W C K
30
86.7%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y W G N N G N W C T L S H E C M A W C K
30
86.7%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G W C T T H E C M S W C K
1
C S T N T F S L S D Y W G N R G Y W C T L T H E C M S W C K
30
86.7%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N N G C T T H E C M S W C K
1
C S T N T F S L S D Y W G N N G W L C T I T H E C M S W C K
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G W C T +H E C M S W C K
1
C S T N T F S L S D Y W G N K G G W C T I S H E C M S W C K
30
83.3%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y G N N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y M G N N G N W C T I S H E C M A W C K
30
83.3%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15350_lanthipeptide
Lanthipeptides: BHL26_RS15350_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C T T N T F S L S D Y W G N+G+W C+ +H E C M S W C K
1
C T T N T F S L S D Y W G N D G S W C S L S H E C M S W C K
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
C+T N T F S L S D Y W G N G N W C T +H E C M+W C K
1
C S T N T F S L S D Y W G N R G N W C T L S H E C M A W C K
30

#### MIBiG 4.0 matches for CQS04_RS09620

66.7%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C
29
C T T N T F S L S+ G N N G W C T T E C C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
36.7%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F S L S D Y W G N N G N W C T A T H E C M S W C
29
+++S G N G +C T T E C M C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T A T H E C M S W C
29
C T + E C C
28
C T L S K E C Q P N C
38
CQS04_RS09625
Leader:
MHNKSIHENSEKELELGRYLESDMLALTDDEVAGG
Core:
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
Core with dehydrations:
A Dhb P Dhb I V I Dhb A I Dhb G Y I Dha A N Dha Cys P Dhb Dhb A Cys Dhb R A Cys

#### antiSMASH-DB 4.0 matches for CQS04_RS09625

100.0%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
82.1%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T I V I T A+T G Y I S N+C P T T+C T R A C
2
T P T I V I T A V T G Y I S T N T C P T T S C T R A C
28
63.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T +I +T A++G Y I S+N+C P T T A C T R A C
4
T V S I A L T A V S G Y I S S N T C P T T A C T R A C
30
with 101 more sequence matches
Only the first 10 are displayed here.
60.7%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
7
I T A I T G Y I S A N S C P T T A C T R A C
28
++ I T G Y I S+N+C P T T A C T R A C
5
L S V I T G Y I S S N T C P T T A C T R A C
26
60.7%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P I I ++G+I S N+C P+T A C T R A C
2
T P A I S I-L V S G F I S T N T C P S T A C T R A C
27
59.4%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
1
A T P-T I V I T A I T G Y I S A N S C P T T A C T R A C
28
A T P T V I A++ Y+S +C P T T A C T R A C
4
A T P A T P V I V A V S A Y V S D K T C P T T A C T R A C
32
57.6%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
1
A T P T I V I--T A I T G Y I S A N S C P T T A C T R A C
28
A T P +V A+T +I S A N+C P T T+C T R A C
4
A T P W L V K A S V A V T A F I S A N T C P T T S C T R A C
33
57.6%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
2
T P T I V-----I T A I T G Y I S A N S C P T T A C T R A C
28
T P T++ +T A++G Y I S+N+C P+T A C T R A C
2
T P T V L A T T G A L T A V S G Y I S S N T C P S T A C T R A C
33
57.1%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T I V I+ ++ Y+S N+C P T T+C T C
1
T P T I V I S V V S A Y V S T N T C P T T S C T D E C
27
54.8%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
A T P T I V I---T A I T G Y I S A N S C P T T A C T R A C
28
T P T I I A++G+I S +C P T+ C T R A C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
53.6%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
A T P T I V I T A I T G Y I S A N S C P T T A C T R A C
28
T P T+V++ ++ +I S N+C P++A C T R A C
1
G T P T V V L S I V S A W I S N N T C P S S A C T R A C
28
53.6%
NZ_JALAPU010000003.1 and 7 others:
NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07925_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00585_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17010_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04640_lanthipeptide
Lanthipeptides: MOD17_RS07925_lanthipeptide
7
I T A I T G Y I S A N S C P T T A C T R A C
28
++ +T Y I S+N+C P T T A C T R A C
5
L S V V T A Y I S S N T C P T T A C T R A C
26
53.3%
NZ_QGEE01000020.1 and 3 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06165_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05385_lanthipeptide
Lanthipeptides: DKP74_RS06165_lanthipeptide
2
T P T I V I T A I--T G Y I S A N S C P T T A C T R A C
28
T P I +A+ +G++S+++C P T T A C T R A C
2
T P V I G Y S A V I V S G F V S S H T C P T T A C T R A C
30

#### MIBiG 4.0 matches for CQS04_RS09625

25.0%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
19
C P T T A C T R A C
28
C P T T C T C
17
C P T T K C T S K C
26
24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
14
I S A N S C P T T A C T R A C
28
+S A C P T T C T C
23
V S A A F C P T T K C T S R C
37

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57
Confidence: strong
ToxT
Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.31 out of 18.57
Confidence: strong
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.93 out of 27.78
Confidence: medium
Additional weak hits (6):
ArgR
Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 17.13 out of 20.01
Confidence: weak
LuxO
Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 21.78 out of 26.12
Confidence: weak
AfsQ1
Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.94 out of 19.52
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 22.98 out of 31.73
Confidence: weak
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 22.81 out of 31.73
Confidence: weak
NuR
Description: Nickel-responsive regulator
Species: Streptomyces coelicolor
Score: 22.00 out of 30.98
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

CQS04_RS09620 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3315.4 Da
  Molecular weight: 3317.6 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3335.6 Da N = 1
    3353.7 Da N = 2
    3371.7 Da N = 3
    3389.7 Da N = 4
CQS04_RS09625 - Class II
  Cleavage pHMM score: 0.60
  RODEO score: 0
  Monoisotopic mass: 2637.4 Da
  Molecular weight: 2639.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2657.1 Da N = 1
    2675.1 Da N = 2
    2693.1 Da N = 3
    2711.1 Da N = 4
    2729.1 Da N = 5
    2747.2 Da N = 6
CQS04_RS09620 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3315.4 Da
  Molecular weight: 3317.6 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3335.6 Da N = 1
    3353.7 Da N = 2
    3371.7 Da N = 3
    3389.7 Da N = 4
CQS04_RS09625 - Class II
  Cleavage pHMM score: 0.60
  RODEO score: 0
  Monoisotopic mass: 2637.4 Da
  Molecular weight: 2639.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2657.1 Da N = 1
    2675.1 Da N = 2
    2693.1 Da N = 3
    2711.1 Da N = 4
    2729.1 Da N = 5
    2747.2 Da N = 6

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
ToxT | Regulator of MSHA biosynthesis

NZ_PCGR01000003.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 271,934 - 292,767 nt. (total: 20,834 nt) Show pHMM detection rules used
terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
CQS04_RS10405: dehydrogenase

smcogs
  SMCOG1222: dehydrogenase

CQS04_RS10410: dehydrogenase

smcogs
  SMCOG1222: dehydrogenase

CQS04_RS10435: dehydrogenase

smcogs
  SMCOG1222: dehydrogenase

Transferases: acyltransferase
CQS04_RS10425: acyltransferase

smcogs
  SMCOG1141: acyltransferase

Lyases: dehydratase
CQS04_RS10395: NAD-dependent epimerase/dehydratase

smcogs
  SMCOG1010: NAD-dependent epimerase/dehydratase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.3 |  | 0.70 | terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000647.3 |  | 0.69 | terpene | carotenoid | Rhodobacter sphaeroides
BGC0000646.5 |  | 0.47 | terpene | β-carotein | uncultured bacterium
BGC0000648.3 |  | 0.44 | terpene | carotenoid | Myxococcus xanthus
BGC0000664.5 |  | 0.42 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.3 |  | 0.41 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.3 |  | 0.41 | terpene | carotenoid | Streptomyces avermitilis
BGC0001456.3 |  | 0.40 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000643.3 |  | 0.40 | terpene | carotenoid | Brevundimonas vesicularis
BGC0000640.3 |  | 0.40 | terpene | carotenoid | Enterobacteriaceae bacterium DC404

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.3 |  | 0.70 | terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000647.3 |  | 0.69 | terpene | carotenoid | Rhodobacter sphaeroides
BGC0000646.5 |  | 0.47 | terpene | β-carotein | uncultured bacterium
BGC0000648.3 |  | 0.44 | terpene | carotenoid | Myxococcus xanthus
BGC0000664.5 |  | 0.42 | terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.3 |  | 0.41 | terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.3 |  | 0.41 | terpene | carotenoid | Streptomyces avermitilis
BGC0001456.3 |  | 0.40 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000643.3 |  | 0.40 | terpene | carotenoid | Brevundimonas vesicularis
BGC0000640.3 |  | 0.40 | terpene | carotenoid | Enterobacteriaceae bacterium DC404

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
triterpene | C30 carotenoid | diapophytoene | C30 | acyclic | none

Genes with terpene domains:
CQS04_RS10415: PT_phytoene_like
Domain 1 (4 - 276): Prenyltransferase; Phytoene synthase like
Subtype: Diapophytoene synthase

Reactions:
  FPP → diapophytoene

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 20.87 out of 23.79
Confidence: strong
Additional weak hits (1):
NrdR
Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 20.38 out of 27.18
Confidence: weak
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
FPP | Farnesyl diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
IolR | Regulator of the inositol catabolism