LOCUS       NZ_BEWI01000032        20792 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Sphingobium fuliginis strain OMI SOMI032, whole genome shotgun
            sequence.
ACCESSION   NZ_BEWI01000032
VERSION     NZ_BEWI01000032.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Sphingobium fuliginis
  ORGANISM  Sphingobium fuliginis
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1
  AUTHORS   Ogata,Y., Toyama,T., Yu,N., Wang,X., Sei,K. and Ike,M.
  TITLE     Occurrence of 4-tert-butylphenol (4-t-BP) biodegradation in an
            aquatic sample caused by the presence of Spirodela polyrrhiza and
            isolation of a 4-t-BP-utilizing bacterium
  JOURNAL   Biodegradation 24 (2), 191-202 (2013)
   PUBMED   22777343
REFERENCE   2
  AUTHORS   Ogata,Y., Goda,S., Toyama,T., Sei,K. and Ike,M.
  TITLE     The 4-tert-butylphenol-utilizing bacterium Sphingobium fuliginis OMI
            can degrade bisphenols via phenolic ring hydroxylation and
            meta-cleavage pathway
  JOURNAL   Environ Sci Technol 47 (2), 1017-1023 (2013)
   PUBMED   23215053
REFERENCE   3
  AUTHORS   Takada,K., Shiba,T., Soda,S., Inoue,D., Miyake,M., Eguchi,M. and
            Ike,M.
  TITLE     Bioaugmenting a lab-scale membrane bioreactor with Sphingobium
            fuliginis OMI to degrade 4-tert-butylphenol
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 2787552)
  AUTHORS   Kuroda,M., Ogata,Y., Inoude,D., Sei,K. and Ike,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2017) Contact:Masashi Kuroda Osaka University,
            Graduate School of Engineering; Yamadaoka 2-1, Suita, Osaka
            565-0871, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 5.3
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Roche GS FLX Titanium Chemistry
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002723855.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 02:52:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,410
            CDSs (total)                      :: 5,341
            Genes (coding)                    :: 5,170
            CDSs (with protein)               :: 5,170
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 49 of 171
            Pseudo Genes (incomplete)         :: 133 of 171
            Pseudo Genes (internal stop)      :: 8 of 171
            Pseudo Genes (multiple problems)  :: 15 of 171
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:08:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1907375
            Orig. end                         :: 1928167
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BEWI01000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20792
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="5"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..20792
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20792
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10792](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10792
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     misc_feature    218..233
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            complement(488..1777)
                     /locus_tag="SFOMI_RS21720"
                     /old_locus_tag="SFOMI_4393"
     CDS             complement(488..1777)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686399.1"
                     /locus_tag="SFOMI_RS21720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4393"
                     /product="MFS transporter"
                     /protein_id="WP_025551318.1"
                     /transl_table=11
                     /translation="MLSATLARQMGTRQIHYGWAVLAATFFTMLVVAGAVGAPGVFIIP
                     LQKEFGWSSADISGALAIRFLLFGGMGPFAAAFMNRFGVRRMMLISLSIIVGGLLLSMG
                     MTRLWHLVLLWGVVIGIGTGLTAMVLGATVATRWFAHRRGLVMGLLSASTATGQLAFLP
                     LLAALTERFGWRASVLLVCGAILLAAMVVLLLMRDRPADLGLPPYGESEVHPAPPQPAS
                     FGALLMSPLRILADAARVPSFWILFFSFYICGASTNGLVQTHFIALCGDYGLAAVGAAS
                     MLAMMGLFDFAGTLASGWLSDRFDNRWLLFWYYGLRGLSLLYLPFSDFSFYSLSVFAMF
                     YGLDWVATVPPTVKLTAQRFGPERANVVFGWIFAGHQLGAASAALAGGLSRTVWQSYMP
                     AFVAAGILCLIGAGLVLLINRGRSKTFVLA"
     misc_feature    complement(1845..1859)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.83"
                     /tool="antismash"
     gene            complement(1898..2854)
                     /locus_tag="SFOMI_RS21725"
                     /old_locus_tag="SFOMI_4394"
     CDS             complement(1898..2854)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008830328.1"
                     /locus_tag="SFOMI_RS21725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4394"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_025551316.1"
                     /transl_table=11
                     /translation="MAKTGRVAHIRENIVLYGALLANIGIAVAKFVASALTGSSSMLTE
                     GVHSMVDSGNQLLLLYGQARAKKPADAAHPFGYGRELYFWAFVVAILIFAVGAGVSIYE
                     GWLHIRQPEPLRDPAVNYIVLAIAFLMEGASWTIAVREFGRKRGPSSWWQSIRRSKDPA
                     GFIVLFEDSAALIGLIVAAIGVWASHYFGNARLDGVASIVIGLVLGAVAVLLAREAKGL
                     LIGESADRAIIDAVWALLDRRPEITAVNHIRTIHTAPDAVFVAISADFADDLRMGRAES
                     LIEEMESEMKRAIPELTSIYIRPEKREDALVQPRASA"
     gene            complement(2861..3469)
                     /locus_tag="SFOMI_RS21730"
                     /old_locus_tag="SFOMI_4395"
     CDS             complement(2861..3469)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004209542.1"
                     /locus_tag="SFOMI_RS21730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4395"
                     /product="flavodoxin family protein"
                     /protein_id="WP_025551314.1"
                     /transl_table=11
                     /translation="MVLKALALNCSLKAGDGESSSTDAMIAVLAKALAAHDVELTGTVR
                     VAALDIRPGVTSDEGEGDAWPALRRRILDHDIVIFGGPIWLGQISSVAKRVLERMDAFL
                     GEADERGRMPSYGKVAVAAIVGNEDGAHFSTAQWFQALNDVGWTIPATAACYWVGEAMG
                     SIDFKDLGEVPEKVEKTAKMVAGNAAHLAGLLRSSPYPG"
     gene            3566..4417
                     /locus_tag="SFOMI_RS21735"
                     /old_locus_tag="SFOMI_4396"
     CDS             3566..4417
                     /EC_number="1.1.1.47"
                     /NRPS_PKS="Domain: PKS_KR (39-201). E-value: 2.4e-11.
                     Score: 35.8. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS21735_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821230.1"
                     /locus_tag="SFOMI_RS21735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4396"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_044661049.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-34, bitscore:
                     115.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTEEMIHEDGLPGHESRLEPKPEWEPRYPGSGRLAGKVAIVTG
                     ADSGIGRAVAALYAREGADVAIFYLCEHDDAEKTAGIVRAEGRRALTIAGDLGDRDFCQ
                     RAVAQVVEQFGRIDILVNNAGEQHPDSDITDISEEQLRRTFQTNIFAMFFLTQAVRPHL
                     KRGAAIVNCTSVTMYQGSKELLDYSSTKGAITAFTRSLSENLVGDGIRVNAVAPGPIWT
                     PLNPSGGASPEKLEHFGESTPMGRPGQPNEVAPSFLFLACDDASYMSGQVLHPNGGTIV
                     NG"
     aSDomain        3683..4168
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS21735_PKS_KR.1"
                     /evalue="2.40E-11"
                     /label="SFOMI_RS21735_PKS_KR.1"
                     /locus_tag="SFOMI_RS21735"
                     /protein_end="201"
                     /protein_start="39"
                     /score="35.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGADSGIGRAVAALYAREGADVAIFYLCEHDDAEKTAGIVR
                     AEGRRALTIAGDLGDRDFCQRAVAQVVEQFGRIDILVNNAGEQHPDSDITDISEEQLRR
                     TFQTNIFAMFFLTQAVRPHLKRGAAIVNCTSVTMYQGSKELLDYSSTKGAITAFTRSL"
     gene            complement(4608..6725)
                     /locus_tag="SFOMI_RS21740"
                     /old_locus_tag="SFOMI_4397"
     CDS             complement(4608..6725)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007686394.1"
                     /locus_tag="SFOMI_RS21740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4397"
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_025551311.1"
                     /transl_table=11
                     /translation="MDGDQQILASAGVLRWSVDGDGLCHPDAATASRFGVRDGQPLLRW
                     FRGVHRIFRKPVLQLARAVLRMGRAEATLTLEDREGVMRNMRVVARIRRDGAGRPAADL
                     VMIDVTTEHAEIGRLRRSTENLRLIVEYNPQLPWLADPDGRIIDFTDRWLESSGLDREE
                     AEGNGWLAATHPDDIGPLTHRITHSLTTGEPFDVRVRLMVNDQYRWMRAQAYPRRDEEG
                     RIIRWYGYTEDIHESVLIEEQIRWNAEHDSLTQLPNRAMFNACLDKALASAMTDFKKVG
                     VFLLDIDNFKDVNDLMGHHAGDELLKSFASRLKEIFAGDGVVARLGGDEFAILIENVES
                     RQQLADLANRVLTIRETLFAAGRSLECRGSIGVAAFPEDGRVATELLRHADLALYRAKS
                     LGRGRMQMFEQSLLEDMQERVAMINRARTAVRDGTIISYYQPKVSLQTGELVGFEALLR
                     WRDSCGTIRSPAEIYAAFDDHDVADMIGQTMTSQVFADMAAWRARGLTLGHVAINVSSA
                     ELRRERFAGRLIETMDRFSIAPDSIEIEITEGVFLGAGSDTVRRSIDELHMCNIPLALD
                     DFGTGFASLSHLRSLPVSTLKIDRSFVSGVTARESDAAIVSALITLGRALNMKVVAEGV
                     EEADQSVKLRELGCDYAQGFYFGRPAPSENIPALIQSWSENSAIITLNRRAAPWSPRGM
                     RGEGRADSLTA"
     gene            complement(6897..9089)
                     /locus_tag="SFOMI_RS21745"
                     /old_locus_tag="SFOMI_4398"
     CDS             complement(6897..9089)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1107:
                     TonB-dependent receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054096.1"
                     /locus_tag="SFOMI_RS21745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4398"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_065846771.1"
                     /transl_table=11
                     /translation="MTNFGYRRRWKWALLVSATIELAASGTARAQAPADADMRADITVT
                     ARKVPEPLLKAPLAVTSISGDSIVAAGLQTITDLTRMAPNVDIGGGIAGQLQGQISIRG
                     ISTLVRNIGLETGVGIYVDDVYVGRPENFVQHLLDVDRVEIVRGPQGTEYGKNTIAGVV
                     NVQTKQPDADPGASIRLDAGNYDYRRGEAVLGTRLNERLSVRGAVAYARQDGFYKHLSG
                     GRDAGSTDLLTWRLSAKYAPTDQLSFIARWEGLRDRGTPAFFQADALAGYPADFPSREP
                     LHINNNRPNRLHRDSQGISLRTEWASDAITLTAITAYRDSSYHASLDDDQEQVDFVSAD
                     NFSDDSHFFSQELRLAGGTGKLRYLLGAYYFDQMVRTDRGLGLGADTGVPGEPMLTTKG
                     SVKTESGALFGRLDYELTDRLSLSAGLRYTREKKRAHFVQDDASGTGIFTYLGFPNLTF
                     DGRSTDDDLSPSATISYEVVPDANVYARFSRGFKSAAYNVDLASSLGGLTASPEKATSY
                     EVGFKMLTLDRRMRLNLAAFHTDYDRLQVSQVLGSGLALTNAGRAQVEGVEGELSLQLT
                     SRLRLEGNAAILDAHYKRFDNCGVPASVIPSVGSPSTDCTGNDLVLAPHFTGYGAVSYE
                     VPVRIGTIFARADVDHRSTVYFEPTNSDAFKAGPRTLVNLRFGLRRGQWDIAAWVQNLT
                     DRIYKTYADDRSGLGVYRTAAYGPPRTYGVSLSAAF"
     misc_feature    9108..9117
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
     misc_feature    9140..9157
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.57"
                     /tool="antismash"
     misc_feature    complement(9225..9238)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.24"
                     /tool="antismash"
     gene            9333..9881
                     /locus_tag="SFOMI_RS21750"
                     /old_locus_tag="SFOMI_4401"
     CDS             9333..9881
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821234.1"
                     /locus_tag="SFOMI_RS21750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4401"
                     /product="hypothetical protein"
                     /protein_id="WP_025551310.1"
                     /transl_table=11
                     /translation="MSEYIPSTQLRAGSSTTAADFNAGVDSTLSIESLVTRFSQALGLQ
                     AASHACYAVGDGERRFLFGETGWCGPIAQPEVLPQICFPITGWDERQYEVEIRLLSMLE
                     SPEERANLHAMATLYLCRGIALLDARDDLAASALTETELFCLDQRQAGWCDLDIAEALD
                     RSVQAVKVHVQRARQKQAA"
     gene            10001..10792
                     /locus_tag="SFOMI_RS21755"
                     /old_locus_tag="SFOMI_4402"
     CDS             10001..10792
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821235.1"
                     /locus_tag="SFOMI_RS21755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4402"
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_025551308.1"
                     /sec_met_domain="Autoind_synth (E-value: 1.3e-24, bitscore:
                     84.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHLISKNNSALYQDEIRDLHQARAEVFVNQLGWDLRVEDGLEYD
                     EYDDARASNIIGFSTENRVVMGLRFRPTDDCSMLLDHFSHVLPAGIRPIDDGRTWELSR
                     GFCIERGMRRHNLRRKAACMIAPLELAYEAGIDRCVGFTDVRMLSFCYGVGWKLTLLGS
                     AMDYGQGEAVAYEVEVSQAALDEMRQMWGLPRPSHITIDQLLPEEENVHVAAARLAREH
                     PELQKIAAQPEIGSVTHPSATTGADVYYGRFGATRSASGGH"
     gene            10792..11094
                     /locus_tag="SFOMI_RS21760"
                     /old_locus_tag="SFOMI_4403"
     CDS             10792..11094
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (16-81). E-value: 3.4e-13.
                     Score: 41.7. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS21760_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821236.1"
                     /locus_tag="SFOMI_RS21760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4403"
                     /product="acyl carrier protein"
                     /protein_id="WP_025551306.1"
                     /sec_met_domain="PP-binding (E-value: 3e-10, bitscore:
                     37.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSDLIRQASAEEIESWIIARIAEIVNVAPAAVSPDAPFDSFGID
                     SAKAISLMVELENWLNLPDELPLELLFEAEAIRDAATGIAAAVSDMAAQQGGVRP"
     aSDomain        10840..11034
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS21760_PP-binding.1"
                     /evalue="3.40E-13"
                     /label="SFOMI_RS21760_PP-binding.1"
                     /locus_tag="SFOMI_RS21760"
                     /protein_end="81"
                     /protein_start="16"
                     /score="41.7"
                     /tool="antismash"
                     /translation="WIIARIAEIVNVAPAAVSPDAPFDSFGIDSAKAISLMVELENWLN
                     LPDELPLELLFEAEAIRDAA"
     gene            11091..11957
                     /locus_tag="SFOMI_RS21765"
                     /old_locus_tag="SFOMI_4404"
     CDS             11091..11957
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054099.1"
                     /locus_tag="SFOMI_RS21765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4404"
                     /product="cyclopropane-fatty-acyl-phospholipid synthase
                     family protein"
                     /protein_id="WP_025551304.1"
                     /transl_table=11
                     /translation="MIQDEQIEFGGSAAAIRHHYDVGNDFYSAWLDPSMTYSSAMWDGL
                     PKDAPLEEAQQRKLDYHAESVGAGEGMRILDVGCGWGGMMRNLRRRHGAAECVGLTLSE
                     EQLAYIEQSGDPGIGAVLSNWHDYRPDRPFDAIISVGAFEHFAHPQQSVDERRGVYREF
                     FQACRDWMEGKGRLSLQTIAYGRMSPEDANPFIANEIFPAAELPTLEDIVVACKGLFRV
                     ERLRDDGLDYARTCEMWSNRLRGAVRSGVVDPAIHPVEKYSRYLRMSAAGFRMRKIGLL
                     RIAFATE"
     gene            12075..13871
                     /locus_tag="SFOMI_RS21770"
                     /old_locus_tag="SFOMI_4405"
     CDS             12075..13871
                     /NRPS_PKS="Domain: CAL_domain (153-478). E-value: 3.8e-97.
                     Score: 317.4. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS21770_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013849347.1"
                     /locus_tag="SFOMI_RS21770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4405"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_099187047.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 6.7e-183, bitscore:
                     607.3, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3e-79, bitscore:
                     263.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIDFSRSIVDIVLDHGNSVPDRPALIFDQGDGPQSSLTYAQVAA
                     QVGQLAGAMAARGLAAGGLAAGGLAGPRIALLFSAGTDFALALLACLAVGGVAIPLAPV
                     GRRKARLRNILNMLDDIRPDCILLDDGMAGLFGEELSAALSAGPVRYLEFAALAAESHA
                     FSPLALAPVRLAVLQFTSGTTSNPKGVMISHGNIIANETMIRAAFGHDRDSHFVGWVPH
                     YHDQGLFGNILQPLFLGSTCVITSPAAFINRPMSWLQLISRYRAHTSGGPNFGYDLCVD
                     HATRRGMPDGLDLSGWRVAFNGAERVRPATLDRFAECFADAGFDRRAFLPCYGLAESTL
                     VTIAVPPRSDPIVKSYDSRALAAGRAVESAGGDAVLDLACCGPAMAGAEARIVDPETGE
                     ALPDGAVGEIWLRGPHITAGYIDNPAATEASFGRLDEGGPFLRTGDLGFSTADGFFIVS
                     RLKDLIIVRGRNHAPSDVEQIWSELSGTVGQASAAAVEIEMGDAQHIVLIAEMKRDDAR
                     SLSDEKLQDLAARLRATAMERLELAITDLVMVPASAIPRTTSGKVQRKQAGRMLMDGEL
                     TVLGMAGPLAQAFAPSGQRASA"
     aSDomain        12534..13508
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS21770_CAL_domain.1"
                     /evalue="3.80E-97"
                     /label="SFOMI_RS21770_CAL_domain.1"
                     /locus_tag="SFOMI_RS21770"
                     /protein_end="478"
                     /protein_start="153"
                     /score="317.4"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="FAALAAESHAFSPLALAPVRLAVLQFTSGTTSNPKGVMISHGNII
                     ANETMIRAAFGHDRDSHFVGWVPHYHDQGLFGNILQPLFLGSTCVITSPAAFINRPMSW
                     LQLISRYRAHTSGGPNFGYDLCVDHATRRGMPDGLDLSGWRVAFNGAERVRPATLDRFA
                     ECFADAGFDRRAFLPCYGLAESTLVTIAVPPRSDPIVKSYDSRALAAGRAVESAGGDAV
                     LDLACCGPAMAGAEARIVDPETGEALPDGAVGEIWLRGPHITAGYIDNPAATEASFGRL
                     DEGGPFLRTGDLGFSTADGFFIVSRLKDLIIVRGRNHAPSDVEQ"
     CDS_motif       12597..12656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS21770_0001"
                     /evalue="1.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="SFOMI_RS21770"
                     /protein_end="194"
                     /protein_start="174"
                     /score="23.9"
                     /tool="antismash"
                     /translation="AVLQFTSGTTSNPKGVMISH"
     CDS_motif       13278..13367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS21770_0002"
                     /evalue="3.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="SFOMI_RS21770"
                     /protein_end="431"
                     /protein_start="401"
                     /score="32.3"
                     /tool="antismash"
                     /translation="PDGAVGEIWLRGPHITAGYIDNPAATEASF"
     gene            14187..14765
                     /locus_tag="SFOMI_RS21775"
                     /old_locus_tag="SFOMI_4406"
     CDS             14187..14765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821239.1"
                     /locus_tag="SFOMI_RS21775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4406"
                     /product="hypothetical protein"
                     /protein_id="WP_255308974.1"
                     /transl_table=11
                     /translation="MRSAIPLLLAASAGPALAQSTILPEGMAIQLETRQEISSKSARVG
                     DRIELAVAKPVTIGGVTLIPAGSPAVGEVSRVRDNGLLGRSGKLDIKVSTVRAGGMDVP
                     VRGQRNSQGKSGTLGAVGAGIVFLPLAVIVRGKDVKLPAGTLFEVYVDKEVSLGSGVAP
                     GGPAAATPAESRDMPGSIRTVDPNQALGS"
     gene            complement(14784..15686)
                     /locus_tag="SFOMI_RS21780"
                     /old_locus_tag="SFOMI_4407"
     CDS             complement(14784..15686)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004210362.1"
                     /locus_tag="SFOMI_RS21780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4407"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_044661042.1"
                     /transl_table=11
                     /translation="MSINRIGLFHLETLLWIDRLGTFAAAAERLNTTQPAISARVRELE
                     SHLGARLFRREGRTMSFTPAGRQLVRDCGPLWSDLQSMLLRCGGLAEASGVVRIGAGEI
                     AAASCLPDFVSQLKGAMPHVSLELEIDLTANLIQQLLVGRADISFAAGPIAHPALQSRP
                     IGGVSLVWLASPAIAASFHGDAADRTIPIWSLASHSPIYGRMRDAIAASQIARKSLNLC
                     NNARMMIDIAKAGGGIGIFPEPMARADLMSGALVKLEGMPALSPIEFHVARRISDNDPV
                     IAAIFEQASALRLGPEGEG"
     misc_feature    complement(15701..15710)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.35"
                     /tool="antismash"
     misc_feature    15721..15736
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.45"
                     /tool="antismash"
     gene            15771..16482
                     /locus_tag="SFOMI_RS21785"
                     /old_locus_tag="SFOMI_4408"
                     /pseudo=""
     CDS             15771..16482
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010335662.1"
                     /locus_tag="SFOMI_RS21785"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4408"
                     /product="CoA transferase subunit A"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVKKLYSDAASALEGLLFDGMHLCAGGFGLCGIPERLIDAIRDSG
                     VRDLTIASNNAGVDGEGLGKLLRTRQVRKMISSYVGENKEFERQYLAGELEVEFCPQGT
                     LAERCRAGGAGSSGLLHQDGRGHGGGRGQGSEELRRAGLYIGARHLRRCGGHQGLEGR"
     gene            16482..17135
                     /locus_tag="SFOMI_RS21790"
                     /old_locus_tag="SFOMI_4410"
     CDS             16482..17135
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019831808.1"
                     /locus_tag="SFOMI_RS21790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4410"
                     /product="CoA transferase subunit B"
                     /protein_id="WP_044661041.1"
                     /transl_table=11
                     /translation="MAWTRDEMAARAAKELQDGFYVNLGIGIPTLVANHIPDGVEVTLQ
                     SENGMLGIGPFPYEGEEDADLINAGKQTISELPQSCYFSSADSFAMIRGGHIDLTVLGA
                     MEVSEHGDIANWMIPGKMIKGMGGAMDLVAGVKKIIVVMEHTSKDGSPKFIPACTLPLT
                     GRNVVDMIVTDLCVFQRPDHDSPFRLIECAPGVTAEEVAAKTSAHYTVDVAQPA"
     gene            complement(17350..19059)
                     /locus_tag="SFOMI_RS21795"
                     /old_locus_tag="SFOMI_4411"
     CDS             complement(17350..19059)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020821240.1"
                     /locus_tag="SFOMI_RS21795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4411"
                     /product="ATP-binding protein"
                     /protein_id="WP_099186603.1"
                     /transl_table=11
                     /translation="MDRKLASERGAEQKALAARWTIAAEAMEALAGARSMEAIINVLRA
                     FARRAVGADGIAVVLRDEDQCHYIAEDSMEPLWAGQRFPASSCVSGWAMEHHRTAVIPD
                     VFDDPRVPVEAYRTTFVRSMVMVPIGRIEPMAALGAYWSEFAQPTDNEIALLEALARAA
                     STALENGRLFASLEALNDQLERRVRERTTELERSQDSLRQVQKLDMLGQLTGHVAHDFN
                     NLLMPIVGGLDLILSGKRTPESIERHATIAMQAAESAQTLVQRLLTFARRQPLTAKAVD
                     LSDLLGGMQALLTSTLGPRIALSVDLQPMLPPVRADAHQLEVALLNLAVNGRDAMPDGG
                     ALSIKAQARQSRLPAALTPGPYVCLTVSDTGTGMTPAVKAAAMEPFFTTKPSGHGTGLG
                     LSMVHGLAAQLGGTVEIDSAVGQGTSVRLWLPVERAPAVKAASPAVEEGPKERSGKVLL
                     VDDNDLVRNSTREMLIDMGYEVVDTDRAERALSMIESGDRPDILITDHIMPGMTGVELA
                     LRLRADHPHIALLIISGYEGVDLIAPDITRLSKPFRHNHLQACIAAARAQAA"
     gene            complement(19253..20413)
                     /locus_tag="SFOMI_RS21800"
                     /old_locus_tag="SFOMI_4413"
     CDS             complement(19253..20413)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019052357.1"
                     /locus_tag="SFOMI_RS21800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_4413"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_044661040.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-06, bitscore:
                     25.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAYIVEALRTAGGKRKGALSGVHPADLGAVVLNALVDRSGIDP
                     AAVEDVILGCVTQGGEQSFAFGRNVVLASKLPDSVPAVTIDRQCGSSQQALHFAAQAVM
                     SGTQDLVIAAGVESMTRVPMGSNFNLHAQAGIGEGPWPASIRERYGVNEFSQYHGGQAI
                     ADKYGFSREDMDAYALESHRKAAAAIAAGAFEREIVPVDTPDGRFAQDEGVRANGSMEA
                     LAGLKTLTEGGTITAGNASQMTDGASAVLVANEEALKRFDLRPLARIHNLTVTAGDPVI
                     MLEEPIAATERALRRAGLGLDEIDLFEVNEAFASIPMAWLKVLGADPGKLNVHGGAIAL
                     GHPLGASGTKLMATLVHGLRARGKRYGLQAMCEGGGIANVTIVEAL"
ORIGIN
        1 gtccagcccg cccttcgcca tggtgtaggc cgcgtcgccg gaccgggcga tctggcccgc
       61 gatggacgtg acgttgacga tccgcccgcc ctccttcatc ccggccgcga tggtgcgggc
      121 gaggtcgaag ggcgcgacca gattgacctc cagcatccgc cgcaccgcgg gccggtccag
      181 ttctccaatc ggcctgcggt cgcgatggcc tgcattgttg accaatatgt cgatcgggcc
      241 gcaggggccg agcgccgccc gcagcgcttc gccatcctgc aggtcgaaga tcagcggcgc
      301 gctcgtcccg cccgaggcgg cgatggcggc ggcggtcgcc tcaagctgct cgacatttcg
      361 gccatggagc aggacatgcg cgccggcccc ggccaggccc agcgcgatct cgcgtcccag
      421 gccgcgtccg gctccggtga cgagggcgat ttttccttgc agcatccaag cctctccaca
      481 cagccggtca ggcgaggacg aaggtcttgc tccgcccgcg attgatcagc agcaccagcc
      541 ccgccccgat caggcacaat atccccgccg cgacgaaggc gggcatatag ctttgccaga
      601 cggtgcgcga aaggccgccc gccagcgccg cgctcgccgc gccgagctga tgcccggcga
      661 agatccagcc gaacacgaca ttggcccgct ccggtccgaa acgctgcgcc gtcagcttga
      721 ccgtcggcgg cacggtcgcg acccagtcga ggccgtagaa catcgcgaag accgacaggc
      781 tgtagaacga gaagtcgcta aacggcagat agagcagcga aaggccgcgc agcccataat
      841 accagaacag cagccagcga ttgtcgaacc ggtccgacag ccagcccgac gccagcgtgc
      901 ccgcgaaatc gaacagcccc atcatcgcca gcatcgacgc cgcgcccacc gccgccagcc
      961 catagtcgcc gcaaagcgcg atgaaatgcg tctggaccag cccgttggtg ctggcgccgc
     1021 agatgtagaa ggaaaagaac aatatccaga agctgggcac ccgcgcggca tcggccaaga
     1081 tgcggagcgg gctcatcaac agggcgccga agctggcggg ctgcggcggg gcgggatgca
     1141 cctcgctctc gccatagggc ggcaggccga ggtcggcggg acggtcgcgc atcagcagca
     1201 gcacgaccat cgccgccagc aggatcgcgc cgcacaccag caggaccgag gcgcgccagc
     1261 cgaaccgctc cgtcagcgcg gcgagcagcg gcaggaaggc cagctgaccc gtggcggtgc
     1321 tggccgacag cagccccatg accagcccgc gcctgtgcgc gaaccagcgc gtggcgacgg
     1381 tggcgcccag caccatggcg gtgagcccgg tgccgatgcc gatgacgacg ccccacagca
     1441 ggacgagatg ccacaatcgg gtcatgccca tcgacagcag cagtccgccg acgatgatgg
     1501 acagcgagat cagcatcatc cgccgcacgc cgaagcggtt catgaaggcg gcggcgaacg
     1561 ggcccatccc gccgaacagc aggaaacgga tcgccagcgc cccggaaata tccgccgaac
     1621 tccagccgaa ttccttttgc agggggatga tgaacacgcc gggcgcgccc acggcgccgg
     1681 cgacgaccag catggtgaag aaggtcgcgg ccagcacggc ccatccataa tggatttgcc
     1741 gcgtgcccat ttggcgggcg agagtcgctg acagcatgaa ggccttcctc ccggatcgat
     1801 cgaccggcgt tagatgacga tcgtcatcag atggtcaagg ggccaattga cggaatatgg
     1861 acgtggaagg ccgcgaacag gcggggcggg ccggccgtca ggcggaagcg cgcggctgga
     1921 ccagggcgtc ctcccgcttt tccggacgga tatagatgga ggtgagttcg ggaatcgccc
     1981 gcttcatctc gctttccatc tcctcgatca ggctttcggc ccggcccatg cgcagatcgt
     2041 cggcgaaatc ggcgctgatc gccacgaaca ccgcgtcggg cgcggtgtgg atggtgcgga
     2101 tgtgattgac ggcggtgatc tccggccgcc ggtcgagcag cgcccagacc gcgtcgatga
     2161 tggcccggtc ggcgctctcc ccgataagca ggcccttggc ctcccgcgcc agcagcaccg
     2221 ccaccgcgcc cagcaccagc ccgatgacga tggaggcgac gccgtccagc cgcgcattgc
     2281 cgaaataatg gctggcccag acgccgatgg ccgccacgat cagcccgatc agcgcggcgc
     2341 tgtcctcgaa caggacgatg aagccggccg ggtccttcga ccggcggatc gattgccacc
     2401 aactgctggg gccgcgcttg cgtccgaatt cccgcacggc gatggtccag gatgcgccct
     2461 ccatcaggaa ggcgatggcc aggacgatgt agttgacggc ggggtcgcgc agcggctccg
     2521 gctgccgaat atggagccag ccttcataaa tggatacgcc cgcgccgacc gcgaagatca
     2581 ggatggcgac gacgaaggcc cagaaataca gctcccgccc atagccgaag ggatgggcgg
     2641 cgtcggcggg cttcttcgcc ctggcctgac catagagcag cagcaactgg ttgccgctgt
     2701 cgaccatcga atgcaccccc tccgtcagca tggaggagga gccggtcagg gccgaggcga
     2761 cgaacttggc gaccgcaatg ccgatattgg ccagcagcgc gccgtaaagg acgatatttt
     2821 cccggatgtg cgcgacgcgg ccggttttcg ccacctgggt tcagcccgga tagggggagg
     2881 accggagcag gccggccaga tgcgccgcat tgcccgccac catcttcgcg gtcttctcca
     2941 ccttctccgg cacctccccc agatccttga aatcgatcga gcccatagct tcccccaccc
     3001 aatagcaggc ggccgtggcc ggaatcgtcc agccgacatc gttcagcgcc tgaaaccatt
     3061 gcgcggtcga aaaatgcgcc ccgtcttcat tgccgacaat cgccgcgacc gcaaccttgc
     3121 catagctcgg catgcggccc cgctcgtctg cctcgcccag aaaggcgtcc atgcgttcca
     3181 gcacccgctt ggcgacgctg ctgatctgcc ccagccagat cgggccgccg aagatcacta
     3241 tgtcatggtc caatatcctg cggcgcaacg ccggccaggc gtcgccctct ccttcatcgg
     3301 acgtcacgcc gggcctgatg tcgagcgccg cgacccgcac cgtgccggtg agttcgacat
     3361 catgggcggc aagggccttc gccagcaccg cgatcatcgc gtcggtcgag ctggattcgc
     3421 cgtcccccgc cttgaggctg cagttgaggg ccagggcttt cagaaccatc gcatgtctcc
     3481 atccgcccca tccacgcgcc gaaccgggct ccagccaatg aactccccag caggcaatgt
     3541 gttcttcggg gaaaggagat ttgcgatgcc cgataccgaa gagatgatcc atgaggatgg
     3601 cctgcccggc catgaaagcc ggctggagcc caagcccgaa tgggaaccgc gctatcccgg
     3661 ctccggccgg ctggcgggca aggtggcgat cgtcaccggc gccgacagcg gaatcgggcg
     3721 ggcggtcgcg gcgctctatg cccgcgaagg ggccgatgtc gcgatcttct acctctgcga
     3781 acatgacgac gcggaaaaga ccgccgggat cgttagggcg gaagggcggc gggcgctcac
     3841 gatcgcgggc gacctgggcg accgggactt ctgccagcgg gccgtggcgc aggtggtcga
     3901 gcagttcggg cggatcgaca tcctcgtcaa caatgcgggc gagcagcacc cggacagcga
     3961 catcaccgac atcagcgagg aacagctgcg ccgcaccttc cagaccaaca tcttcgccat
     4021 gttcttcctg acgcaggcgg tccgcccgca tctgaagcgc ggggcggcga tcgtcaactg
     4081 cacctccgtc accatgtatc aggggtcgaa ggaactgctc gactattcca gcaccaaggg
     4141 ggcgatcacc gccttcaccc ggtcgctgtc cgaaaatctg gtgggggacg gcatcagggt
     4201 gaacgccgtc gcgccgggtc cgatctggac cccgctcaac cccagcggcg gggcaagtcc
     4261 ggaaaagctg gagcatttcg gggaaagcac gcccatgggc aggccgggcc agcccaatga
     4321 agtcgccccg tccttcctct tcctcgcctg cgatgacgcc agctacatgt cggggcaggt
     4381 gctgcatccc aatgggggca ccatcgtcaa cggctagagc caatcgtgcg gaaaagctgc
     4441 cctgagcctg ccgacgggcg ggaaccggtt ttccgcctga aaggatcgga caacagaaag
     4501 ctggagcacg cgacccgcgt ccgatctggc gcagcgtgct ccaggcgcga gcggattgaa
     4561 gccgcatcac gtcgctgcgc ctcacctgac cgggatccgg tcttccctca ggcggtcagc
     4621 gagtccgcgc ggccttcccc gcgcatcccg cgcggagacc agggcgcggc ccgccggttc
     4681 agggtgatga tggcgctatt ctcgctccac gactggatca gcgcgggaat attctccgac
     4741 ggcgcggggc ggccgaaata gaaaccctgg gcatagtcgc agcccagttc gcgcagcttg
     4801 accgactggt ccgcttcctc gacgccttcc gccaccacct tcatgttgag cgcgcggccc
     4861 agcgtgatca gcgcggaaac gatggcggca tcgctttcgc gcgccgtcac gccgctgacg
     4921 aaggaacggt cgatcttcag cgtgctgacg ggcagcgacc gcaaatggga aagcgaggcg
     4981 aagccggtcc cgaaatcgtc cagcgccagc gggatgttgc acatgtgcag ttcgtcgatg
     5041 gaacggcgca ccgtgtccga ccccgcgccc aggaacaccc cttcggtgat ctcgatctct
     5101 atggaatcgg gcgcgatgga gaagcggtcc atggtctcga tcaagcgtcc ggcaaagcgt
     5161 tcccgccgca attcggccga ggacacgttg atggcgacat gccccagcgt cagcccgcgc
     5221 gcgcgccatg cggccatgtc ggcgaacacc tggctggtca tcgtctggcc gatcatgtcg
     5281 gcgacgtcat gatcgtcgaa cgccgcgtag atttcggcgg gcgagcggat ggtgccgcaa
     5341 ctgtcgcgcc accgcagcag cgcttcgaac ccgaccagtt cgcccgtctg caacgacacc
     5401 ttgggctgat aatagctgat gatcgtgccg tcgcgcacgg cggtccgcgc ccggttgatc
     5461 atggccacgc gctcctgcat gtcctccagc agcgactgct cgaacatctg catgcgcccc
     5521 cggcccagcg acttggcgcg ataaagcgcc aggtcggcat ggcgcagcag ttccgtcgcg
     5581 acccggccat cctcggggaa tgcggccacg ccgatgctgc cgcggcattc gagcgagcgc
     5641 ccggcggcga acagcgtctc ccgaatggtg aggacgcgat tggcgagatc ggcaagctgc
     5701 tgtcggcttt cgacattctc gatcaatatg gcgaactcgt cgccgcccag ccgcgccacc
     5761 accccgtcgc cggcgaagat ttccttgagg cgggaggcaa agctcttcaa cagctcgtca
     5821 ccggcatgat ggcccatcag gtcgttgacg tccttgaaat tgtcgatgtc gagcaggaag
     5881 acgccgacct tcttgaagtc ggtcatggcg ctcgccagcg ccttgtccag gcaggcgttg
     5941 aacatcgccc ggttgggcag ttgcgtcagc gaatcatgct cggcgttcca gcgtatctgc
     6001 tcctcgatca gcacgctttc atggatgtcc tcggtatagc cgtaccagcg gatgatccgg
     6061 ccttcctcgt cgcgccgggg ataggcctgc gcccgcatcc agcgatactg gtcgttgacc
     6121 atcagccgca cgcgcacgtc gaagggctcg ccggtggtca gcgaatgggt gatccggtgg
     6181 gtcagcgggc cgatgtcatc cggatgcgtc gccgcaagcc agccattgcc ctccgcctcc
     6241 tcccggtcca ggccggaact ttccagccag cgatcggtga agtcgatgat ccggccgtcg
     6301 ggatcggcca gccagggaag ctgaggatta tattcgacga tcaggcgcag attttccgtg
     6361 ctgcggcgca gccgtccgat ttcggcatgt tcggtcgtga cgtcgatcat caccaggtcg
     6421 gccgccggcc ggcccgcccc gtcacgacgg atgcgcgcga cgacacgcat attcctcatg
     6481 acgccttcac gatcctccag cgtcagcgtc gcttcggccc tgcccatgcg cagaacggcg
     6541 cgggcaagct ggagcacggg cttgcgaaag atccggtgca cgccgcggaa ccagcgaagc
     6601 agcggctggc cgtcccgcac gccgaaacgg ctcgcggtgg cggcatcggg atggcatagc
     6661 ccatccccgt caaccgacca ccgcaagacc cctgccgacg ccagtatctg ctggtcgcca
     6721 tccatcgggt cctgcctgcc ttgaaattca tcaggtgacc gcgatgaaat ctggtccgcc
     6781 attctactcc tgctgtcccg gcgccgcggc ccttaagaag gtttcaccat ttgctggcta
     6841 agatttcctt aatggccgcc atatgggcca tagccagcac gcccaagcgc aacgtcctaa
     6901 aatgccgccg aaaggctgac gccataggtg cgcggcggcc cgtatgccgc cgttcggtac
     6961 acgcccagac cggaccggtc gtcggcatag gtcttgtaga tcctgtcggt caggttctgg
     7021 acccaggcgg cgatgtccca ctgcccgcga cgcaggccga aacgcaggtt gaccagcgtg
     7081 cgcggcccgg ccttgaaggc gtccgaattg gtcggctcga aatagacggt cgaccggtga
     7141 tccacatccg cgcgggcgaa gatcgtgccg atccgcaccg gaacctcata gctgacggcg
     7201 ccatagccgg tgaaatgggg cgccaggacc aggtcgttgc cggtgcagtc ggtgctgggg
     7261 ctgccgacag agggaatgac cgatgcggga acgccgcaat tgtcgaacct cttataatgt
     7321 gcgtccagaa tggcggcatt cccctccagc cgcagccggg acgtcagttg cagcgacagc
     7381 tcgccttcca cgccctccac ctgcgcgcgg ccggcattgg tgagcgccag cccgctgccc
     7441 agcacctgcg acacctgcaa ccggtcgtaa tcggtgtgga acgcggcaag gttcagccgc
     7501 atccgccggt ccagcgtcag catcttgaag ccgacctcat agctggtcgc cttttccggg
     7561 ctggcggtca gcccgcccag cgaagaggcg aggtcgacat tgtaagccgc gctcttgaag
     7621 ccgcgggaga agcgcgcata gacattggcg tccggcacga cctcatagga aatggtcgcg
     7681 ctgggcgaca ggtcgtcatc ggtcgaccgg ccgtcgaagg tgaggttcgg gaagcccaga
     7741 taggtgaaga tacccgtccc gctggcgtca tcctggacga aatgggcgcg cttcttctcc
     7801 ctggtgtagc gcaggccggc ggaaagcgac aggcgatcgg tcagttcata gtcgagccgc
     7861 ccgaacagcg ccccgctctc cgtcttgacg ctgcccttgg tggtcagcat cggttcgccc
     7921 ggcacgcccg tatcggcgcc cagacccagg ccccggtcgg tgcgcaccat ctggtcgaaa
     7981 taataggcgc ccagcagata gcgcagcttg ccggtgccgc ccgccagccg cagttcctgg
     8041 ctgaagaaat gggaatcgtc gctgaaattg tccgcggaga cgaagtcgac ctgctcctga
     8101 tcgtcgtcca gcgaggcatg ataggaggaa tcgcgatagg cggtgatggc cgtcagcgtg
     8161 atcgcgtccg atgcccattc cgtcctcagc gaaatgccct ggctgtcgcg gtgcaaccgg
     8221 ttgggccggt tgttgttgat gtgcagcggc tcccgcgaag ggaaatccgc cggatagccg
     8281 gccagcgcgt ccgcctggaa gaaggcgggc gtgccgcggt cgcgcagccc ctcccaccgg
     8341 gcgatgaagg acagttggtc ggtcggcgca tatttggccg acagccgcca ggtcagcagg
     8401 tcggtcgatc ccgcatccct gccgccggac agatgcttgt agaagccgtc ctgccgggca
     8461 taggccaccg caccgcgcac cgaaagccgt tcgttgaggc gcgtgcccag caccgcctcg
     8521 ccccgcctgt aatcgtaatt gcccgcgtcc agccggatgg aggcgccggg atcggcgtcg
     8581 ggctgcttcg tctggacgtt gacgacgccg gcgatggtgt tcttgccata ttccgtccct
     8641 tgcgggccgc gcacgatttc cacccggtcg acatccagaa gatgctggac gaaattttcc
     8701 ggccggccga catagacatc gtccacatag atgccgacgc cggtttccag cccgatattg
     8761 cggaccaggg tggagatgcc gcggatcgag atctgcccct gcaactggcc tgcaatgccc
     8821 ccgccgatgt cgacattggg ggccatgcgg gtcaggtcgg tgatggtctg caaccccgcc
     8881 gccacgatcg aatcgcccga aatgctggtg accgccagcg gcgccttcag cagcggttcc
     8941 ggcaccttgc gcgccgtcac cgtgatgtcg gcgcgcatgt ccgcatcggc cggggcctgc
     9001 gcccgggccg tgccggaagc tgccagttcg atcgtcgcgg aaaccagaag tgcccacttc
     9061 catcgccgcc tgtacccaaa attcgtcatc gcccacgaaa cccgctatat tttttcaatc
     9121 cgccgatcat aggcggactt ggtaaaccgc tggttaaact cttcctgcgt ccggctccgg
     9181 atcggacgag cttgcgctct gcggccggcg gccccgcaac ccggcgaacg ctcgttccgc
     9241 cgcaaacagg aatcaggcgg caggaaggca cgcttaaccc gcttttaaga cctgacgcgg
     9301 catgacggca ggcatatgcc gcgtgaggaa ccatgagcga atatatcccc agcacccagc
     9361 ttcgcgccgg aagttcgacc accgccgccg atttcaacgc gggggtcgac agcacgctca
     9421 gcatcgagag cctcgtcacc cgcttcagcc aggccctggg ccttcaggcg gcgagccatg
     9481 cctgctacgc tgtcggcgat ggggagcggc gcttcctgtt cggtgagacc ggctggtgcg
     9541 ggccgatcgc acagccggag gtcctgccgc agatctgctt tccgatcacc ggctgggacg
     9601 aacggcaata tgaggttgag atccgcctgc tgagcatgct ggaaagcccg gaggaacgcg
     9661 cgaacctgca cgccatggcg acgctctacc tgtgccgggg catcgccctg ctcgacgcgc
     9721 gcgacgatct ggccgcgtcc gccctgaccg agaccgagct gttctgcctc gaccagcggc
     9781 aggccgggtg gtgcgacctc gacattgccg aggcactcga ccgctccgtc caggcggtga
     9841 aggtgcatgt ccagcgcgcc cggcagaagc aggccgcctg aacccccttt atcgaccggg
     9901 ttttttgcgg ggaacatgga ttgcaccctg caactttccg atgacctccc ctgtataata
     9961 tgttacaggc gctgccgctg catgcggggg acgaacggat ttgattcatc tgatttcgaa
    10021 gaacaattcc gcactgtacc aggacgagat cagagatttg caccaggccc gcgcggaggt
    10081 gttcgtcaac cagctcggct gggatctcag ggtcgaggac ggattggaat atgacgaata
    10141 tgatgatgcg cgcgcgagca acatcatagg cttttcgacc gagaaccggg tcgtcatggg
    10201 gctgcgtttc cgccccaccg acgactgttc catgctgctc gatcattttt cgcatgtcct
    10261 gcccgccggc atccgcccca tcgacgacgg gcgcacctgg gaactgagcc gcggattctg
    10321 cattgagcgg ggcatgcgcc gccacaatct gcgacggaag gccgcgtgca tgatcgcgcc
    10381 gctggaactg gcctatgagg ccgggatcga ccgttgcgtg ggcttcaccg atgtccgcat
    10441 gctcagcttc tgctacggcg tcggctggaa gctgaccctg ctcggttccg ccatggacta
    10501 tggccagggg gaggccgtcg cctatgaggt ggaggtgtcg caggccgcgc tcgacgagat
    10561 gcgccagatg tggggcctgc cccggccttc gcacatcacc atcgaccagc ttcttccgga
    10621 ggaggagaat gtgcacgtcg cggcggcccg gctggcgcgc gagcatccgg aactgcagaa
    10681 gatcgccgcc cagccggaga tcggttccgt cacacacccg tccgccacga ccggggcgga
    10741 cgtctattat ggcagattcg gggcgacccg ttcggcttca gggggacatt gatgaattcc
    10801 gaccttattc gacaggcatc ggcagaggaa atcgaaagct ggatcattgc ccgcatcgct
    10861 gaaatcgtga atgtggcgcc cgccgccgtc tctcccgatg cgccgttcga cagtttcggg
    10921 atcgattccg ccaaggcgat ctcgctgatg gtggagctgg agaactggct gaacctgccc
    10981 gacgaactgc cgctggaact gttgttcgag gcggaggcga tccgcgacgc ggcgacgggc
    11041 atcgccgcgg cggtcagcga catggcggcg cagcagggcg gcgtccggcc atgatccagg
    11101 acgaacagat cgaatttggc ggatcggccg ccgccatccg ccaccattat gatgtcggca
    11161 acgacttcta ttcggcgtgg ctcgacccca gcatgaccta ttccagcgcg atgtgggacg
    11221 gcctgcccaa ggacgccccg ctggaggagg cgcagcagcg caagctcgac tatcatgcgg
    11281 aatcggtcgg cgccggcgag ggcatgcgca tattggacgt cggttgcggc tggggcggca
    11341 tgatgcgcaa cctgcggcgc aggcatggcg ccgccgaatg cgtcggcctg acgctgagcg
    11401 aggaacagct cgcctatatc gagcaatcgg gcgatcccgg catcggcgcg gtcctttcca
    11461 actggcacga ctatcgtccc gacaggccgt tcgatgcgat catctccgtc ggcgcgttcg
    11521 agcatttcgc ccatccgcag cagagcgtgg acgagcgccg cggcgtgtac cgcgaattct
    11581 tccaggcctg ccgcgactgg atggaaggga agggccgtct gtcgctccag accatcgcct
    11641 atggcaggat gtcgccggag gacgccaatc ccttcattgc gaacgagatc ttcccggcgg
    11701 cggaactgcc gacgctggag gacatcgtgg tcgcctgcaa gggtctgttc cgcgtcgagc
    11761 ggctgcgcga cgacgggctg gactatgcgc gcacctgcga gatgtggagt aaccggctgc
    11821 gcggcgcggt ccgcagcggg gtggtggatc cggccatcca tccggtcgag aaatattccc
    11881 gttatctgcg catgtcggcc gccggtttcc gcatgcggaa gatcggcctg ctccggatag
    11941 ccttcgcgac ggaatgacca gaatatcccg gccagcgggc ggaatcgcct ggcgaccggg
    12001 accatgcggc atcaaaggac tgggcgtttt cgctccatgt gaaaaggctc caaagcatcg
    12061 ggttcgcaaa aaagatgcag atagacttca gccggtcgat cgtcgacatc gtactggacc
    12121 atgggaacag cgtcccggac cggccggcgc tgatattcga ccagggcgac ggtccgcaga
    12181 gcagcctgac ctatgcgcag gtggcggcgc aggtcgggca gcttgccggc gccatggcgg
    12241 cacgggggtt ggcggcgggg gggttggcgg cgggggggct ggccggtccc cggatcgccc
    12301 tcctcttctc ggcggggacc gacttcgcgc tcgcgctgct tgcctgcctc gcggtcggcg
    12361 gcgtcgccat tccgctcgcc ccggtcggcc ggcgcaaagc gcggcttcgg aatatcctga
    12421 acatgctgga cgacatccgg cccgactgca tcctgctgga cgacggcatg gccggcctgt
    12481 tcggggagga actgtccgcc gccctgtccg ccggcccggt gcgctatctg gaatttgccg
    12541 cgctcgcggc ggaatcgcac gccttctcgc cgctggcgct cgcgccggtc cggctcgccg
    12601 tgctccagtt cacctccggc acaacgtcga acccgaaggg ggtgatgatc agccatggca
    12661 acatcatcgc caatgagacg atgatccgcg ccgccttcgg ccacgaccgg gattcccatt
    12721 tcgtcggctg ggtgccgcat tatcacgatc aggggctgtt cgggaacatc ctgcaaccgc
    12781 tgttcctggg ctcgacctgc gtgatcacct cgcccgccgc gttcatcaac aggccaatgt
    12841 cctggctgca actcatttcc cgttatcgcg cgcataccag cggcgggccc aatttcggct
    12901 acgacctctg cgtcgaccat gccacgcggc ggggcatgcc ggacggtctc gacctgtcgg
    12961 gctggcgcgt cgcgttcaac ggggcggagc gggtgcggcc cgccacgctc gaccgctttg
    13021 ccgaatgctt tgccgatgcc ggtttcgaca ggcgcgcctt cctgccctgc tatggactgg
    13081 ctgaatccac cctcgtgacc atcgcggttc cgccccggag cgaccccatc gtcaagagct
    13141 acgacagccg cgctctcgcg gcaggtcggg cggtggagag cgccggcggg gacgccgtgc
    13201 tggacctcgc ctgctgcggc cccgccatgg ccggggcgga ggcgcggatc gtcgatcccg
    13261 aaaccggcga ggcgctgccc gatggcgcgg tgggcgaaat ctggctgcgc ggcccgcaca
    13321 tcaccgccgg ctatatcgac aatcccgccg cgacggaggc gagcttcggc cggctggacg
    13381 aaggcgggcc gttcctgcgc accggcgatc tcggcttttc cacggccgat ggatttttca
    13441 tcgtcagccg cctcaaggac ctgatcatcg tccggggccg caaccatgcg cccagcgatg
    13501 tcgaacagat ctggtcggaa ctttccggca cggtgggaca ggcaagcgcc gccgccgtgg
    13561 agatcgagat gggcgatgcg cagcatatcg tcctgatcgc ggagatgaag cgcgacgacg
    13621 cccggtccct gtcggacgag aaactccagg accttgccgc ccggctgcgc gccacggcca
    13681 tggagcggct ggaactggcc atcaccgatc tggtgatggt gcccgccagc gcgatccccc
    13741 gcacgaccag cggcaaggtg cagcgcaagc aggccggcag gatgctgatg gacggggaat
    13801 tgacggtgct gggcatggcg gggccgctgg cgcaggcgtt cgcgccgtcc gggcaaaggg
    13861 catccgcctg agttcatcct gacagggctg aacgcggttc ggcccgacag gtgaaaccct
    13921 gagggccggg atcggccggc gtccgcccga ccgtctcccg catcggcatc cgcgcgaagg
    13981 cgcgaccagc gcccggttga acgcggcgcg ttctggctga cggtcggcac agcggaaggt
    14041 cgtcgcggca atggctgcgc cgttcgcccg cgccaggtcc gactcgttcc ttgatgccct
    14101 ggccccggaa gcgtaaattg cacggcggtc gggggcgtgg ccgccgaagc ggagaggatg
    14161 gaccgatgat tcgcctgtca ttgccgatgc gctctgccat ccccctgctg ctggcggcga
    14221 gcgcgggtcc cgcccttgcc caatcgacga tccttcccga aggcatggcc atccaactgg
    14281 aaacccggca ggagatttcc tccaaatccg cccgcgtcgg cgacaggatc gaactggccg
    14341 tggccaagcc cgtgacgatc ggcggcgtga cgctcatccc cgccggcagc ccggcggtgg
    14401 gggaagtgag ccgcgtcagg gacaatggcc tgctcggccg atcgggcaag ctcgacatca
    14461 aggtcagcac ggtcagggcg ggcgggatgg acgtgccggt gcgcggccag cgcaattccc
    14521 agggcaagtc cggcaccctg ggcgcggtgg gcgcgggcat cgtcttcctt ccgctggcgg
    14581 tgatcgtccg cggaaaggac gtcaagctgc ccgccggcac gctgttcgag gtctatgtcg
    14641 acaaggaggt ttccctggga tcgggcgtgg cgccgggcgg cccggccgcc gccactccgg
    14701 ccgaaagccg cgacatgccc ggcagcataa ggaccgtcga tcccaatcag gcgctgggtt
    14761 cctgaagccc gtctcggcag cggtcagccc tcgccctccg gccccagccg cagcgcgctc
    14821 gcctgctcga aaatggcggc gatcaccgga tcattgtccg aaatacgcct ggccacatga
    14881 aactcgatgg gcgacagggc cggcatgccc tccagtttca caagggctcc gctcatcagg
    14941 tcggcgcggg ccatgggttc cgggaagatg ccgatcccgc cacccgcctt ggcgatgtcg
    15001 atcatcatcc gcgcattgtt gcacaggttc agcgatttac gggcgatctg cgaagcggcg
    15061 atcgcgtcgc gcatccgccc atagatcggg gaatggctgg ccagcgacca gatcggaatg
    15121 gtgcggtccg ccgcatcgcc gtggaatgac gcggcaatgg cgggactggc gagccagacc
    15181 aggctcaccc cgccgatggg acgcgactgg agcgcaggat gcgcgatcgg cccggccgcg
    15241 aaggaaatat cggcgcgccc gaccagcaat tgctggatca ggttggcggt caggtcgatt
    15301 tccagttcca ggctgacatg cggcattgcc cccttcaatt gcgacacgaa gtccggaagg
    15361 cagcttgccg cggcgatttc gcctgcgccg atgcggacca cgccgctcgc ttccgccaat
    15421 ccgccgcagc gcagcagcat gctctgcaga tcgctccaga gaggtccgca atcgcgcacc
    15481 agttgccgcc cggcgggggt gaaggacatg gtccggcctt cgcggcggaa caggcgggcg
    15541 cccagatggc tctccagttc ccttacccgc gccgaaatcg ccggctgggt ggtgttcaac
    15601 cgctccgccg ccgcagcgaa cgtgccgagc cggtcgatcc agagcagggt ttccagatgg
    15661 aagaggccaa tgcgattaat agacatggct tttggctaaa gcaaaaaaca aatcattaga
    15721 aatgataatt ggcctccgcc agaatggcga tccgaaggag aggcatgctt atggtcaaaa
    15781 agctttattc ggatgcggcg agtgcgttgg agggtttgct gttcgacggc atgcatctgt
    15841 gcgctggcgg gttcggtctg tgcgggatac ccgagcggct gatcgatgcg atccgggatt
    15901 cgggcgtcag ggatctgacc atcgcctcca acaatgcggg ggtagatggc gaagggctgg
    15961 gcaagctgct gcgcacccgt caggtcagga agatgatctc cagctatgtg ggcgagaaca
    16021 aggagttcga gcggcaatat ctggccgggg agctggaggt ggagttctgc ccgcagggca
    16081 cgctggccga acgctgccgg gcgggcggcg cgggcagttc cgggcttcta caccaggacg
    16141 ggcgtgggca cggcggtggc cgagggcaag gaagtgaaga gcttcgacgg gcaggattat
    16201 atattggagc gcggcatctt cgccgatgtg gcggtcatca agggctggaa ggccgatgag
    16261 agcggcaacc tcatcttccg caagacggcg cgcaacttca accagcccat ggcgacggcg
    16321 gcgaagatct gcgtcgcgga agtggaggag gtggtgccca ccggcagcct cgaccccgat
    16381 gcgatccatc tgcccggcat ctacgtcaag cgcatgatcg tcggagcgcc ttacgacaag
    16441 aaaatcgaat tccgcaccgt ccgccagagg gaggccgcat aatggcatgg actcgtgacg
    16501 aaatggccgc gcgggcggcg aaggaattgc aggacggttt ctacgtgaac ctgggcatcg
    16561 gcatcccgac gctggtggcg aaccacattc ccgatggcgt ggaagtgacg ctgcagtcgg
    16621 agaatggcat gctgggcatc ggccctttcc cctatgaggg ggaggaggat gccgacctga
    16681 tcaatgcggg caagcagacg atcagcgaat tgccgcagag ctgctatttt tccagcgccg
    16741 acagcttcgc gatgatccgg ggcgggcata tcgacctgac cgtgctgggc gcgatggagg
    16801 tttcggaaca tggcgacatc gccaactgga tgatcccggg caagatgatc aagggcatgg
    16861 gcggcgcgat ggatctggtc gcgggcgtca agaagatcat cgtcgtcatg gaacacacgt
    16921 ccaaggacgg cagtcccaag ttcatcccgg cctgcaccct gccgctgacg ggcaggaatg
    16981 tggtcgacat gatcgtcacc gacctctgcg tgttccagcg gcccgaccat gacagcccgt
    17041 tccgcctcat cgaatgcgcg ccgggcgtga cggcggagga agtcgccgcc aagaccagtg
    17101 cgcattacac ggtggacgtc gctcaaccgg cctgaggaaa gagggcgagg cccctcccgt
    17161 caatgggcct cgccgcctca ggcatgaaag cgaatgcgcc ctgggtcgcg tcgtccgatc
    17221 cacggcaaag tcatcctgtt cagggatagc ctgaatagag tgaagcgaag cgccacagga
    17281 catatccggg ccaggccggc gccaagcttt tctccgcaga ggggccgtga ccccgaaaca
    17341 ggatgcggat caggctgcct gcgcccgcgc cgcggctatg caggcctgca agtgattatg
    17401 ccggaagggc ttggacaggc gcgtgatgtc gggcgcgatc aggtcaaccc cctcatagcc
    17461 cgatatgatc agcaacgcga tgtgcggatg atcggcccgc aggcgcagcg ccagttccac
    17521 ccccgtcatg cccggcatga tatggtcggt gatcaggatg tccggccggt cgccggattc
    17581 gatcatgctg agcgcgcgtt cggcccggtc ggtgtcgacc acctcatagc ccatgtcgat
    17641 cagcatctcc cgcgtgctgt tccggacgag atcgttgtcg tccaccagca gcaccttgcc
    17701 cgaacgctct ttcggcccct cttcgactgc tggggaagcc gccttcaccg caggcgcccg
    17761 ctcgacgggc agccatagcc ggacgctggt gccttgcccc accgcgctgt cgatctccac
    17821 cgtgccgcca agctgggcgg caaggccatg gaccatggaa aggccaagcc ccgtgccatg
    17881 gccggacggc ttggtcgtga agaagggctc catggccgcc gccttgaccg ccggggtcat
    17941 gccggtgccg gtgtcgctga cggtcaggca gacataggga ccgggcgtca gcgcggcggg
    18001 caggcggctt tggcgcgcct gcgcctttat gctgagcgcg ccgccgtcgg gcatggcgtc
    18061 gcggccgttg acggccaggt tgagcagcgc gacctcaagc tgatgggcgt ccgcgcgcac
    18121 cggcggcaac atcggctgga gatcgaccga cagcgcgatc cgcggtccca gcgtgctggt
    18181 cagcaaggcc tgcatcccgc caagcaggtc cgacaggtcg accgcctttg cggtcagggg
    18241 ctggcggcgg gcaaaggtca agagccgctg caccagcgtc tgcgcgctct ccgccgcctg
    18301 catcgcgatg gtcgcatgcc gctcgatcga ttcgggcgtc cgcttgcccg acaggatcag
    18361 gtccagcccg ccgacgatcg gcatcagcag attgttgaag tcatgggcga catggcccgt
    18421 caactggccg agcatgtcca gcttctggac ctggcgcagg ctgtcctgcg accgctccag
    18481 ttccgtggtg cgttcccgga cgcggcgttc gagctggtca ttcagcgctt ccagagacgc
    18541 gaacagccgc ccgttctcca gcgcggtgga cgcggcacgg gcaagcgcct ccagcagcgc
    18601 gatctcattg tcggtgggct gcgcgaattc ggaccagtag gcgcccagag cggccatggg
    18661 ttcgatgcgg ccgatcggca ccatcaccat cgaccgcacg aatgtggtgc gataggcctc
    18721 caccggcacg cggggatcgt cgaagacgtc cgggatcacc gccgtccgat gatgctccat
    18781 cgcccatccg gaaacgcaac tcgatgccgg gaagcgctgc cccgcccaga gcggttccat
    18841 cgaatcttca gcgatataat gacactggtc ctcgtcgcgc aggacgaccg cgatgccgtc
    18901 cgcccccacc gcgcggcgcg cgaaggcccg caggacattt atgatcgctt ccatcgaccg
    18961 cgcgccggcc agcgcctcca tggcttcggc ggctatggtc catcgtgccg ccagcgcctt
    19021 ttgttcggca ccccgttcgc ttgccaattt cctgtccatc gacaaccttc tgcatcggaa
    19081 ccgcgcgtct ttctaacatc ggacggcgtc gatcacaaag cgattatgat caatggctta
    19141 gaggcggcct gggtttgcgg cccgtcaact catccttaac cctgttcatc cgccggtccg
    19201 ccggcgcggg cgccgggcgc gcaagcccgc gacgcccgct ccgcaggaac cgtcacaatg
    19261 cctcgacgat ggtcacattg gcgatgccgc cgccttcgca catggcttgc agcccatagc
    19321 gcttgccccg cgccctcaat ccatggacaa gggtcgccat cagcttcgtc ccgctcgcgc
    19381 cgagagggtg gcccagcgcg atcgcaccgc catggacgtt cagcttgccc ggatcagcgc
    19441 ccagcacctt cagccaggcc atgggaatgg aagcgaaagc ttcgttcact tcgaacaggt
    19501 cgatctcgtc caggcccagc cccgcccggc gcagcgccct ttccgtggcc gcaatcggtt
    19561 cctccagcat gatgacgggg tcgcccgccg tcaccgtcag attatggatg cgcgccagcg
    19621 gcctcaggtc gaaccgcttc agcgcctcct cattcgcgac cagcacggcg gaggcgccat
    19681 cggtcatctg gctcgcattg ccggcggtga tcgtgccgcc ttcggtcagc gtcttgagcc
    19741 cggccagcgc ctccatcgat ccattggcgc gcacgccctc atcctgcgcg aagcggccgt
    19801 ccggcgtgtc gaccggcacg atctcgcgct cgaaagcgcc cgcggcgatg gcggccgcgg
    19861 ccttgcgatg gctctccagc gcgtaggcgt ccatgtcttc gcggctgaag ccatatttgt
    19921 cggcaatcgc ctgcccgcca tggtactggc tgaactcgtt gacgccgtag cgctcgcgga
    19981 tgctggcggg ccatggccct tccccaattc ccgcctgcgc atgcagattg aagttggagc
    20041 ccatcggcac gcgcgtcatg ctttccacgc cggccgcgat caccagatcc tgcgtgccgg
    20101 acatcaccgc ctgcgccgcg aaatgcagcg cctgctgcga cgatccgcac tgccggtcga
    20161 tggtgacggc gggaacgctg tcgggcagct tcgacgccag cacgacattg cggccgaagg
    20221 cgaaggattg ttcgccgccc tgcgtgacgc agcccaatat gacatcctcg accgcggcgg
    20281 gatcgatgcc gctgcggtcg accaatgcgt tcagcaccac ggcgcccaga tccgccggat
    20341 gaacgcccga cagcgcgccc ttgcgcttgc cgccggcagt acgcagcgcc tcgacaatat
    20401 aggcttcggc cattttcagc ttccttcgac atgaggagga gcggcggacc aaaccggttc
    20461 cccgctccag aaggcggcag gcgcgcgcgt ggaaccagcg cttcgcctgc cggggccgct
    20521 caacgcggcg ccattcggat cgcgccgtcc agtcggatga cctcgccgtt cagcatggga
    20581 ttggcgatga tgctgtccac gagctgcgca tattcgtcgg gcttcccaag gcggctggga
    20641 tgcggcacct gcgcgcccag cgcatcctgc acatgctggg ggaacgcctc cagcatgggc
    20701 gtcaggaaga tacccggcgc gatggtcatc acacggatct tgtgctgcgc caggtcgcgg
    20761 gcgatgggca gggtcatgcc gacgacgccg cc
//
