LOCUS       NZ_BEWI01000032        31873 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Sphingobium fuliginis strain OMI SOMI032, whole genome shotgun
            sequence.
ACCESSION   NZ_BEWI01000032
VERSION     NZ_BEWI01000032.1
KEYWORDS    WGS; RefSeq; STANDARD_DRAFT.
SOURCE      Sphingobium fuliginis
  ORGANISM  Sphingobium fuliginis
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingobium.
REFERENCE   1
  AUTHORS   Ogata,Y., Toyama,T., Yu,N., Wang,X., Sei,K. and Ike,M.
  TITLE     Occurrence of 4-tert-butylphenol (4-t-BP) biodegradation in an
            aquatic sample caused by the presence of Spirodela polyrrhiza and
            isolation of a 4-t-BP-utilizing bacterium
  JOURNAL   Biodegradation 24 (2), 191-202 (2013)
   PUBMED   22777343
REFERENCE   2
  AUTHORS   Ogata,Y., Goda,S., Toyama,T., Sei,K. and Ike,M.
  TITLE     The 4-tert-butylphenol-utilizing bacterium Sphingobium fuliginis OMI
            can degrade bisphenols via phenolic ring hydroxylation and
            meta-cleavage pathway
  JOURNAL   Environ Sci Technol 47 (2), 1017-1023 (2013)
   PUBMED   23215053
REFERENCE   3
  AUTHORS   Takada,K., Shiba,T., Soda,S., Inoue,D., Miyake,M., Eguchi,M. and
            Ike,M.
  TITLE     Bioaugmenting a lab-scale membrane bioreactor with Sphingobium
            fuliginis OMI to degrade 4-tert-butylphenol
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 2787552)
  AUTHORS   Kuroda,M., Ogata,Y., Inoude,D., Sei,K. and Ike,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2017) Contact:Masashi Kuroda Osaka University,
            Graduate School of Engineering; Yamadaoka 2-1, Suita, Osaka
            565-0871, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 5.3
            Genome Coverage                   :: 20x
            Sequencing Technology             :: Roche GS FLX Titanium Chemistry
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002723855.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 02:52:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,410
            CDSs (total)                      :: 5,341
            Genes (coding)                    :: 5,170
            CDSs (with protein)               :: 5,170
            Genes (RNA)                       :: 69
            rRNAs                             :: 4, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 171
            CDSs (without protein)            :: 171
            Pseudo Genes (ambiguous residues) :: 0 of 171
            Pseudo Genes (frameshifted)       :: 49 of 171
            Pseudo Genes (incomplete)         :: 133 of 171
            Pseudo Genes (internal stop)      :: 8 of 171
            Pseudo Genes (multiple problems)  :: 15 of 171
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:08:54
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 573071
            Orig. end                         :: 604944
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BEWI01000032.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..31873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31873
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:21873](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..21873)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            735..2453
                     /locus_tag="SFOMI_RS15345"
                     /old_locus_tag="SFOMI_3099"
     CDS             735..2453
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007685143.1"
                     /locus_tag="SFOMI_RS15345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3099"
                     /product="histidine kinase famiy protein"
                     /protein_id="WP_037481508.1"
                     /transl_table=11
                     /translation="MADKDGAEAPVNPNEATGEPAGDLEDTSSYSPTGARPTHHWKRST
                     VAEPGLDQRGTVFFAALQMTRMPMILTDPRQDDNPIVFANKAFLDLTGYEESEVFGRNC
                     RFLQGADTDRETVRALREAVRAQEAISTEILNYRRDGSPFWNAVFVAPVYDDDGTLLYF
                     FASQLDVTRRRSSEQAFRQAQKMEAIGQLTAGLAHDFNNLLQVVTGNLDIVLGDDLNDA
                     QRRMLGNAARAAERGARLTRQLLAFARKTRLEPRRINMNELIHEFGDLIDNTVGPQIRL
                     VTALERRLPAVQIDPTHLEMAVLNILINARDAMPGGGTVTIATELWKLNGNAAAHGLPE
                     GDYVVLSIRDEGHGMSAEVRQRATEPFFSTKGKERGTGLGLAMVHGFVQQSLGRLEIDS
                     EPGQGTTMRLLFPVAPPEEAVSGPVRPMPAPAISGDAGGQTILLVEDSDDVRALASEQL
                     AAIGYRVIPVASGEEALLKLENIKVDLLFTDMVMPGGMSGLELVEKFNELYPETPVLMT
                     TGYNEDLVADIPRGTRLDVIGKPYRREELADRVRTALSRRTVVRREESPFGAKEG"
     gene            2542..3774
                     /locus_tag="SFOMI_RS15350"
                     /old_locus_tag="SFOMI_3100"
     CDS             2542..3774
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013848475.1"
                     /locus_tag="SFOMI_RS15350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3100"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_025547221.1"
                     /transl_table=11
                     /translation="MRGLDIAIAGCGPCGLAAALLLHRAGHHVTLFERFDTPRPIGSGL
                     MLQPTGMAVLFQLGLLEEALARGARVDRLFGKAGRRIVLDVHYAALRHREMFGIGIHRA
                     SLFAILHEAVLQAGIAVHTGRTLTGSAPVGLKRALHFADGETSGPYDLVVDALGTRTAL
                     APPTGRELAYGALWASLDWPQTAAFDPHALAQRYERASIMAGVLPIGTPPGATMPKAAF
                     FWSLRADRLDDWREAGLAPWKAQVAKLWPDCMPLLDQIHDADQLTFARYAHRTLAAPVG
                     PALVHIGDAWHSASPQLGQGANMALLDAWALAQGLAKKNGVDEGIRHAIELRRRHVLTY
                     QWLTALFTPVYQSDSRLLPLIRDRVVGPLSKLWPATAIQAAMVSGLVGNPLPPLGLDGD
                     WTVGMPMAEAA"
     gene            3771..4187
                     /locus_tag="SFOMI_RS15355"
                     /old_locus_tag="SFOMI_3101"
     CDS             3771..4187
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013848474.1"
                     /locus_tag="SFOMI_RS15355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3101"
                     /product="thiol-disulfide oxidoreductase DCC family
                     protein"
                     /protein_id="WP_025547219.1"
                     /transl_table=11
                     /translation="MNDASSDSDGPIIVFDAMCVLCSANAAFVLRHDRAGRFRLASMQG
                     DIGAALNRRFGIDPANPESLIVVEDGRALRDSDAVLAIWAGLDRPWDGLAAFRIVPRWL
                     RDPVYRWIARHRYRLFGKRSTCWVPTTEQARRIL"
     gene            4184..5818
                     /locus_tag="SFOMI_RS15360"
                     /old_locus_tag="SFOMI_3102"
     CDS             4184..5818
                     /GO_function="GO:0016994 - precorrin-6A reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025135.4"
                     /locus_tag="SFOMI_RS15360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3102"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_025547217.1"
                     /transl_table=11
                     /translation="MSRILLLGGYGGFGGRIARRLAAAGHEVLVAGRSIDKARAFCGDA
                     PSLMPLGLDRSRIATALEEHRPDMVVDASGPFQAMDHAIAKACIAAGVHYVDIADSRDF
                     VCGIGALDDAARAAGVILLSGASSVPALSGAAVRHLAQGMDRVRAVEMAISASNKATAG
                     PAVSAAIAGQVGQPLRIWRGQHWAKAFGWQEMRSVQFRCAGTEAITGRKVALVDVPDLA
                     LLPERLAGRPAVTFRAGTELRFQNWALWLASWLVRWRLVATLAPLARFLHPLQSLTRSL
                     GSDRSAMIVHLFGDVAGQKVERRWTLIADRGDGPEIPTLSVVPIVARILSGQEAAGARD
                     AAEALTLSDYADAFGNLAIHHDRAELPAPPPLYDRIMGDRFGQLPPEVRAIHDVFRDGG
                     AAGEATVTGASNPAAALIARIVGFPKAGTHRLHVHFHEADARESWTRNFGGRRFQSHLS
                     QRGRWLVERFGPFRFAFDLPGDAQGLTMVMRRWWIGPLPLPTWLAPRSPAREWAEGGRF
                     HFDVPIALPLIGRLVHYRGWLEPATIR"
     gene            complement(5992..6489)
                     /locus_tag="SFOMI_RS28080"
     CDS             complement(5992..6489)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016462.4"
                     /locus_tag="SFOMI_RS28080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="WP_244968642.1"
                     /transl_table=11
                     /translation="MTIDWLHGLGRTSQLVATASVSDVTYARNNLQDGTIYDLGLSFER
                     ALSARAGASVTFSGTRQTARDPGYATAAGGLTLTGWREAGHTTLFVSTGIRRTEADAAL
                     FLFGARRQEWLMSARTGATFRGLAYRGFAPYVRLAYERNISTTALYEYRRAATEIGITR
                     AF"
     gene            complement(6544..6738)
                     /locus_tag="SFOMI_RS28085"
                     /old_locus_tag="SFOMI_3104"
     CDS             complement(6544..6738)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SFOMI_RS28085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SFOMI_3104"
                     /product="hypothetical protein"
                     /protein_id="WP_025547215.1"
                     /transl_table=11
                     /translation="MRARNPGMACVLLAKPRIGLAKDLALVPRLAGLVNLYRNHEFNDV
                     SGSALIGIEWLHGRDRLSV"
     misc_feature    6763..6781
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    7059..7074
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     gene            complement(7065..7301)
                     /locus_tag="SFOMI_RS28090"
                     /old_locus_tag="SFOMI_3105"
     CDS             complement(7065..7301)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SFOMI_RS28090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SFOMI_3105"
                     /product="hypothetical protein"
                     /protein_id="WP_025547213.1"
                     /transl_table=11
                     /translation="MIRHFGLALALAVAAPAVSARAQTHIDHLSAVDLFGLADRARAAG
                     QIDDAATFYDALARDPDMQVRAGGAVSQGDDVR"
     gene            complement(7298..8128)
                     /locus_tag="SFOMI_RS15370"
                     /old_locus_tag="SFOMI_3106"
     CDS             complement(7298..8128)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013466.4"
                     /locus_tag="SFOMI_RS15370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3106"
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="WP_025547211.1"
                     /transl_table=11
                     /translation="MTVAGGFTGQRDATVQAQNLTLINLTSSQHFYVQYLNNLVGGLNQ
                     QNAETLSFGPPTSDLYGGQFTINDKVAGSDLNFMEYRKTFSSSYDTQDVTLKLYKPGGG
                     NSELALTYASFVHYSTTVPFGTGRQRVDQYGAYGLGTPSGLLAGKTGTGSYRGILYGTG
                     RQYPSNIFYDVKGTSQFAVDFGAQSYTGALAMKGTPSDGSGVIDFGSYDVAGRLTNTGV
                     TGVLTRAGVETGQFAPRFYGPDGEEIVAPFSVTAPTGAAGAGITIQGVAAAKRQ"
     gene            complement(8125..8889)
                     /locus_tag="SFOMI_RS15375"
                     /old_locus_tag="SFOMI_3107"
     CDS             complement(8125..8889)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SFOMI_RS15375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SFOMI_3107"
                     /product="hypothetical protein"
                     /protein_id="WP_025547210.1"
                     /transl_table=11
                     /translation="MITDLKVSQAFQNDAAGMKLGLDLATSTEISRQIRPNSLTVNYDA
                     GTKSYSVSADGWSQRFAPENIQSNANGETIYQKTGGTDRSYLTIATTPYTNSKSNQYVG
                     LAFWQENAVSGTRQDMDFYIFTYGLPTSAATVPRSGVAGFRTDTFGAVSTPGQEPRSFQ
                     GQGDFSVDFAAGVFATHSYLNETTLVTDQGVSGGGIEFTGAGHLSSSSGTFSGNALMRA
                     GLDRPPVLSPGASMAPMERNWVAPFRGRTGTV"
     misc_feature    complement(9017..9034)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.33"
                     /tool="antismash"
     misc_feature    9392..9410
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    complement(9393..9411)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.66"
                     /tool="antismash"
     gene            complement(10001..11608)
                     /locus_tag="SFOMI_RS15380"
                     /old_locus_tag="SFOMI_3108"
     CDS             complement(10001..11608)
                     /NRPS_PKS="Domain: AMP-binding (20-435). E-value: 5.9e-74.
                     Score: 241.0. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS15380_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020372065.1"
                     /locus_tag="SFOMI_RS15380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3108"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_025547209.1"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-83, bitscore:
                     276.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEGLMQRTPLMIGDILRHCATAHGDREIVSRLVGEPAWRYDNRG
                     LRRRAGQAVLALARRGIQPGDRVASLAWNTHRHLELFYAVPGMGAVLHTVNPRFSDDQI
                     VYTINHAGSRLLFVDRSFLPLIHRLRDRIPAVEAVILLASAPDEGFESYEELIAGEADG
                     YDWPSFDENSAAVLCYTSGTTGDPKGVLYSHRSIVLHALANGLPGALGLSAFDCIMPCV
                     PMYHATAWGMPYMAAINGCKLALPCDRMDGESLHSLIRDEGVTFSGGVPTVWTMYLDHL
                     ARTGEDSGTLDRIMIGGSAVPRAMAETFERRHGVKVRQVWGMTELSPLGVISTPTPQIT
                     HLGQEAEEEILWTRQGRVQFGVELRIVGEDGAALPHDGATPGGLQARGPWTVQRYFRSE
                     KDATSDDRWFDTGDIATIDEHGFLRITDRSKDVIKSGGEWISSIDIENVAAACAGVKVA
                     AVIGVRHPQWEERPILIIEGHDGAQLQQQVILDHLASQIAKWWMPDKVIFAPVPLTATG
                     KIDKKRLRERFADELSRI"
     aSDomain        complement(10304..11548)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS15380_AMP-binding.1"
                     /evalue="5.90E-74"
                     /label="SFOMI_RS15380_AMP-binding.1"
                     /locus_tag="SFOMI_RS15380"
                     /protein_end="435"
                     /protein_start="20"
                     /score="241.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ATAHGDREIVSRLVGEPAWRYDNRGLRRRAGQAVLALARRGIQPG
                     DRVASLAWNTHRHLELFYAVPGMGAVLHTVNPRFSDDQIVYTINHAGSRLLFVDRSFLP
                     LIHRLRDRIPAVEAVILLASAPDEGFESYEELIAGEADGYDWPSFDENSAAVLCYTSGT
                     TGDPKGVLYSHRSIVLHALANGLPGALGLSAFDCIMPCVPMYHATAWGMPYMAAINGCK
                     LALPCDRMDGESLHSLIRDEGVTFSGGVPTVWTMYLDHLARTGEDSGTLDRIMIGGSAV
                     PRAMAETFERRHGVKVRQVWGMTELSPLGVISTPTPQITHLGQEAEEEILWTRQGRVQF
                     GVELRIVGEDGAALPHDGATPGGLQARGPWTVQRYFRSEKDATSDDRWFDTGDIATIDE
                     HGFLRITDRSKDVIKS"
     CDS_motif       complement(11027..11086)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS15380_0001"
                     /evalue="4.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="SFOMI_RS15380"
                     /protein_end="194"
                     /protein_start="174"
                     /score="22.3"
                     /tool="antismash"
                     /translation="AVLCYTSGTTGDPKGVLYSH"
     misc_feature    11628..11637
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            complement(11742..12650)
                     /locus_tag="SFOMI_RS15385"
                     /old_locus_tag="SFOMI_3109"
     CDS             complement(11742..12650)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03620.1"
                     /locus_tag="SFOMI_RS15385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3109"
                     /product="TIGR03620 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_025547208.1"
                     /transl_table=11
                     /translation="MAESTFASRMGPLGVFAFTDLMPAAEAAKFAQRVENWGYRTLWVP
                     DVSAGRDSLVHSSWMLANTRELNMVTGIVNIYGRDHVSMRGAQIALAEQSGNRFLLGLG
                     VSHPELVEELRGETYSRKPVATMKAYLEAMERFRMDSTVLPSERPLTVLAALGPKMIEL
                     SASHADGAYTNNSPPAHTAMARAILGPDKLLCVNLLVSLESDPDEARATGRRALAWNLT
                     FPNYRNNWKRLGFDDDDFTDGGSDRLIDAIVAWGDERTIRARIQEHWDAGADHVCIFGL
                     NPAGAYENPEEAPLALLAPAR"
     gene            complement(12807..13595)
                     /locus_tag="SFOMI_RS15390"
                     /old_locus_tag="SFOMI_3110"
     CDS             complement(12807..13595)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-113). E-value: 1.5e-11. Score:
                     36.5. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS15390_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010395484.1"
                     /locus_tag="SFOMI_RS15390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3110"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_025547207.1"
                     /sec_met_domain="adh_short (E-value: 1e-32, bitscore:
                     110.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDLSTKSIIVTGSGRGIGRAMARALAADGAQLTIADIDHAAAS
                     AVAAEIEEAGGRAIAVKVDVTDRASVRAMIAQAIAQFGRLDVMFNNAGTAQGKPFLSIT
                     EEDWHRMMTVNGLSVLICMQEVAARMIEQGQGGKIVNTGSIASKQCHEPLVHYGASKFA
                     VAALTQGGARAFGQHGITVNAIGPGVVKTDLWDSIEGDFRAEGLTRERDEAMDNLIPQI
                     TLGRASVPEDLAGVARFLASSGSDYMTGQCLMVDGGFVFL"
     aSDomain        complement(13257..13571)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS15390_PKS_KR.1"
                     /evalue="1.50E-11"
                     /label="SFOMI_RS15390_PKS_KR.1"
                     /locus_tag="SFOMI_RS15390"
                     /protein_end="113"
                     /protein_start="8"
                     /score="36.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="SIIVTGSGRGIGRAMARALAADGAQLTIADIDHAAASAVAAEIEE
                     AGGRAIAVKVDVTDRASVRAMIAQAIAQFGRLDVMFNNAGTAQGKPFLSITEEDWHRMM
                     T"
     CDS_motif       complement(13500..13571)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS15390_0001"
                     /evalue="8.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SFOMI_RS15390"
                     /protein_end="32"
                     /protein_start="8"
                     /score="15.2"
                     /tool="antismash"
                     /translation="SIIVTGSGRGIGRAMARALAADGA"
     gene            complement(13626..15152)
                     /locus_tag="SFOMI_RS15400"
                     /old_locus_tag="SFOMI_3111"
     CDS             complement(13626..15152)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (9-405). E-value: 8.5e-84.
                     Score: 273.4. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS15400_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="SFOMI_RS15400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3111"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_025547205.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-90, bitscore:
                     300.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINLASDHLRRAAQSFPQGVAIVDGDREILWSDFDRAVERLARRL
                     TTAGLAPGQSVLIMSGNCAEFLILSFAVWRAGGVMAVVHASTGPNELDYALTNAEPHFL
                     FAEGESQTAAAAAVSRTGSRTEIFDLVCNAELIPHIAPFAGDLPQVDCDAVGVIGYTSG
                     TTGVPKPVAHSHRSIAEGTDGVADIWRIDAADTILVAVPLSWMMGLVILSLTATTRAAR
                     IHLMREFSPDGVLDAMLGHGITFFAGSTSMYVKIANAWHRRDAVPDFHLRCCISGGEAR
                     NEAVFEDWRRITGTPVLDAYAAFECWPLVMNDPAGVPPPTGSAGKIAPGARMRFLGPDG
                     REVAPGEVGEAQGRGPAMMMGYWKEPDLTGKAITPDGWYRTGDYARIDEHGYVYVLGRA
                     SDLINRDGRPIYAAEVEQVLSELDYVAQAAVVGLPDADHGQMVAAAIVPMPGAAPSEAA
                     IQEHCAARLAAVKVPGMIRIVEALPHNMSGKVLRREVIPMLLRMREAEDA"
     aSDomain        complement(13938..15125)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS15400_AMP-binding.1"
                     /evalue="8.50E-84"
                     /label="SFOMI_RS15400_AMP-binding.1"
                     /locus_tag="SFOMI_RS15400"
                     /protein_end="405"
                     /protein_start="9"
                     /score="273.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RRAAQSFPQGVAIVDGDREILWSDFDRAVERLARRLTTAGLAPGQ
                     SVLIMSGNCAEFLILSFAVWRAGGVMAVVHASTGPNELDYALTNAEPHFLFAEGESQTA
                     AAAAVSRTGSRTEIFDLVCNAELIPHIAPFAGDLPQVDCDAVGVIGYTSGTTGVPKPVA
                     HSHRSIAEGTDGVADIWRIDAADTILVAVPLSWMMGLVILSLTATTRAARIHLMREFSP
                     DGVLDAMLGHGITFFAGSTSMYVKIANAWHRRDAVPDFHLRCCISGGEARNEAVFEDWR
                     RITGTPVLDAYAAFECWPLVMNDPAGVPPPTGSAGKIAPGARMRFLGPDGREVAPGEVG
                     EAQGRGPAMMMGYWKEPDLTGKAITPDGWYRTGDYARIDEHGYVYVLGRASDLINR"
     CDS_motif       complement(14628..14681)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS15400_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="SFOMI_RS15400"
                     /protein_end="175"
                     /protein_start="157"
                     /score="17.2"
                     /tool="antismash"
                     /translation="IGYTSGTTGVPKPVAHSH"
     gene            complement(15149..16810)
                     /locus_tag="SFOMI_RS15405"
                     /old_locus_tag="SFOMI_3112"
     CDS             complement(15149..16810)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="SFOMI_RS15405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3112"
                     /product="MFS transporter"
                     /protein_id="WP_025547204.1"
                     /transl_table=11
                     /translation="MEASSASLAPDNRVMGGAAAERNAVDGPYARYVLMVLVGVYTLTW
                     MDRTILSILAEDIKAHFGLSDAELGFLHGTAFGVFYALFGFPFGRLADRWKRVRLLSIC
                     ISIWSMMTVFCGLAGSVGQLVAARIGVGIGEASAVPSAYSLLSDWFSRGRRGTALGIFS
                     TGFYLGQGLAFAIGGLVVASWLSSFGEAGPFGLRGWQAAFMVVGLPGLLIAILVSTLRE
                     PRRGLSDGTYPPAEKDIWLRLFDDIASVIPPFTFYQAARTGPKVLAVNIAAALIVASAA
                     WGLIAASGDRMQWIAIAIGWYAAFTAAQMLRARDPATFALTWKAPAFLYTTIGFGFSSM
                     LVLNMGFWTAPLALRSLPVDKATVGMVLGASAAICGMAGVFVGGRLSDIMLRRHAAGRI
                     HVGIASTVIPVPFVIGMCLTHNPWIFFLLNLPVIFVGIMWMAAGAATIQEIVMPRMRGT
                     ASVTYILVSTLVGSALGPYLVGKVSAAQGSLATGLMAGLLAVPIAVAALWMAARHVQSA
                     EATKVERARAAGEAVEQEPVGVPAHAEHRQFERQLS"
     gene            complement(16894..19254)
                     /locus_tag="SFOMI_RS15410"
                     /old_locus_tag="SFOMI_3113"
     CDS             complement(16894..19254)
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1107:
                     TonB-dependent receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012801.4"
                     /locus_tag="SFOMI_RS15410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3113"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_025547202.1"
                     /transl_table=11
                     /translation="MIAMGKWHIAAAKALAGVSAVALAAGAVQAQEAPQAAGADQAAGG
                     GSSVGDIVVTARKRSESLRDVPVAITALSGETLQRQNITQMIDIGKITPSFNYTYGAAN
                     SVAVIRGFGSGGNAGFEQAVGKFVDNVSYGRDQEARIPIFDVERVEVLKGPQVLTFGNS
                     ATAGALNISTKKPGDEFEADGSIGYEFYGREFQAQTGVTVPLSEGMSLRVAGLFQNLDR
                     GRYDNPVKGEREPETRNYAIRPSLRLQPVDGLDIVLRAELDRIKDRGNTLVPTNQPLVG
                     NTSLYPVVGDKDTRYVNTNVAPFFTDELAELEAQLYQADINYDIAGGTLTSTTAWRKSD
                     GVVIYGTDGINHSPAFVNGQWTHYKQFSQELRFGGTFGKLDATVGGYYQRDTLAIDANQ
                     ELNLGALGLTGTAATPFSRNFTFDQKNRVFSAFVDLTYHLTDQLSLSGGVRYSDTRKKA
                     GQSMFAARIIPNIDLDTSRAALLAARDPSLDGVLAAVLGGIQHAFPMGTFHLVDRQWQP
                     QAIVQYKFSPNNMAYVKYVKGAKVGGFDYTYTTSPANDGFGSEKAWMVEAGIKGLLLDN
                     RLDYSIAVFREEFNGLQQSVRQGFNLVVSNIGKARSQGVELDLNYQVTDNLRLGFNGAY
                     LDAKYISFVGAACNTLQNARLAPGCVGGAQDLSGTPTPYSSKWTGSFNVEYVQPVGNGN
                     QIAAGASVFARTKYNAGSFNDPRMVQNGYAQLDAHIDFGPEDGRWAMSLFGRNLTDKRL
                     LEVDYTGVGSSTSTFGSYSRGRQIGLKLRYNIQ"
     misc_feature    19440..19455
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.82"
                     /tool="antismash"
     misc_feature    complement(19657..19670)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(19669..20346)
                     /locus_tag="SFOMI_RS15415"
                     /old_locus_tag="SFOMI_3114"
     CDS             complement(19669..20346)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159: dihydropteridine reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007678770.1"
                     /locus_tag="SFOMI_RS15415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3114"
                     /product="nitroreductase"
                     /protein_id="WP_099186187.1"
                     /sec_met_domain="PF00881 (E-value: 1.9e-28, bitscore: 96.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDESKLFHDVVRERRSVRAFLPTPVPDALMQAVVDDARHAPSNAN
                     IQPWSVHIVSGAKRDELSKAMLEAEAAGRLTPDFPFGYDELYGVYSDRQKAQAAAYYEA
                     LGVAREAFDERRMTMLRNLEFFGAPHACLLFMPSFYDSVRIAGDVGMYAQTFLLSLAAH
                     GLGGVPQTLLGFFAETAREVLGIDPSLKMLFGISFGYPDLDSAASRYWIGKTAIQDHVT
                     FHK"
     gene            complement(20397..20849)
                     /locus_tag="SFOMI_RS15420"
                     /old_locus_tag="SFOMI_3115"
     CDS             complement(20397..20849)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SFOMI_RS15420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SFOMI_3115"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_025547200.1"
                     /transl_table=11
                     /translation="MLDYSLSLEERAVAEKKTRALVDRFIERDVAGDFEACYRMLNADA
                     VYTLIGESPVSGTYYGPDDTMERLAPLLVHFTVRPQMTFSEIMIDGYRAFLRASSTGGA
                     GKYGPYAQPFYGFYLRVEGEGFAELVEFLDPLQLDVALFGKRLVDA"
     gene            complement(20935..21873)
                     /locus_tag="SFOMI_RS15425"
                     /old_locus_tag="SFOMI_3116"
     CDS             complement(20935..21873)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF004283.0"
                     /locus_tag="SFOMI_RS15425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3116"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_025547199.1"
                     /sec_met_domain="HMGL-like (E-value: 5.1e-46, bitscore:
                     154.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPVVIRPVVIREVGLRDGLQMLAAGPTTGQKQAWIDAERAAGLR
                     EMEVCSFVPATLMPQFADAADIVRYARGVEGLTVTALAPNLRGAQLAAEAGVDKINFVI
                     SVSESHNLANVRRTPHESIGQLREIVAMLASLPPDGRPGIDVGLSTAFGCSIEGRVDPE
                     ATLRLAEEVAAAGVDGITIADTVGYADPIAVAGLSAAMLERFADLPIAIHLHDTRGLAL
                     ANAFSAYRAGIRIFDGSLGGLGGCPHAPGATGNVAIEDLIFMFELMGVDTGIDLARLLA
                     ARSAVAAMLPPGALGGQLARAGLPKTMRVAS"
     gene            complement(21879..22688)
                     /locus_tag="SFOMI_RS15430"
                     /old_locus_tag="SFOMI_3117"
     CDS             complement(21879..22688)
                     /NRPS_PKS="Domain: ECH (22-261). E-value: 2.2e-60. Score:
                     195.9. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS15430_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012596.4"
                     /locus_tag="SFOMI_RS15430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3117"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_025547197.1"
                     /transl_table=11
                     /translation="MAHELSFDGLETVRLDHPGDHMLRITLARAGRGNSLNTRMGEELV
                     RIFGALEAKPSLYRCIILTAEGDRIFCAGADLKERNGMDDAAFQEQHYLFERMVRAISD
                     CPIPTIAVVNGAALAGGLELMLGCDFAYAADHARFGFPEVMRGIMPGGGGTQHLARIVG
                     APRAKELILSGAIFGAAEALEWGLVNKIMPGAAIMAAALETAATICANAPIAIAQAKKS
                     IGFGLQMDLRTGLFFEVEAYSRLIGTEDRREGIAAFNEKRPPVFQGR"
     aSDomain        complement(21906..22622)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS15430_ECH.1"
                     /evalue="2.20E-60"
                     /label="SFOMI_RS15430_ECH.1"
                     /locus_tag="SFOMI_RS15430"
                     /protein_end="261"
                     /protein_start="22"
                     /score="195.9"
                     /tool="antismash"
                     /translation="LRITLARAGRGNSLNTRMGEELVRIFGALEAKPSLYRCIILTAEG
                     DRIFCAGADLKERNGMDDAAFQEQHYLFERMVRAISDCPIPTIAVVNGAALAGGLELML
                     GCDFAYAADHARFGFPEVMRGIMPGGGGTQHLARIVGAPRAKELILSGAIFGAAEALEW
                     GLVNKIMPGAAIMAAALETAATICANAPIAIAQAKKSIGFGLQMDLRTGLFFEVEAYSR
                     LIGTEDRREGIAAFNEK"
     gene            complement(22678..23829)
                     /locus_tag="SFOMI_RS15435"
                     /old_locus_tag="SFOMI_3118"
     CDS             complement(22678..23829)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014564.4"
                     /locus_tag="SFOMI_RS15435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3118"
                     /product="CaiB/BaiF CoA-transferase family protein"
                     /protein_id="WP_025547195.1"
                     /transl_table=11
                     /translation="MTRPLPLAGVKVVEIGHSLSAPYAGHILGQLGATVTKIENAGMGD
                     HARAWGSVRHGDAAIMFHAVNLGKESVTADLRDSRSVGQIADLILGEADIVVQNLKRGI
                     VERVGLDAATLRAAKPALIYCNITAFGSTGPLRDHPGYDPLIQAVSGMMSLLGRAGDPS
                     IRIPISVNDMGTGMWACMGILSAYIERSKTGVGATIDTSLYETALAWQTVQISDYLNSG
                     EAPERHGSGNANIVPYQTFFCRNGEELMISAGNDKLFRSLCSVLGAPELGGDPRFATND
                     MRVRNRSALLPMLQAMICERNRPNLEKELEGAGVPCGRVNSIDQVMGSAQVGALGIIGA
                     TSGNELKTVGLPLAFDSCRPPLGRPGPRLGAHDPLETRSHHGA"
     misc_feature    complement(23780..23794)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(23844..25577)
                     /locus_tag="SFOMI_RS15440"
                     /old_locus_tag="SFOMI_3119"
     CDS             complement(23844..25577)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014585.4"
                     /locus_tag="SFOMI_RS15440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3119"
                     /product="hydantoinase B/oxoprolinase family protein"
                     /protein_id="WP_025547193.1"
                     /transl_table=11
                     /translation="MDTITYEIIRSSLYAIAREMKIAMTRTAGSPIIHSGGDASAAIFD
                     DEMQLVAQGNDIPTMLGAAVISTKATVQAIGADNLRPGDVIISNDVYLGGGNHHPDVQF
                     TRPVFAGDRIVAYVMTKGHWSDIGGQSPGSFAAETWDIFGEGVRIPPVRLYRDDRVVED
                     VKTLILQNTRDPETRLLDMQAQYAGCFVGGQRILTLVERYGADALKSAMSRSLDHSEAL
                     MRQALEAMPDGVYLGEDEIDAVYEVDGERPLIPIRVKITKQGDTIEFDYSGSGAQVRGG
                     INCPLSVTYNSTWFTVKAITDNMIPINQGCYRPVKVIAPEGSVLNCSFPASVVSGVTET
                     SPRVIDMLLKALAPAVPQRVTAQSNCAACAGIFAGSDPDEDRVARTGRRFASLFDVHAG
                     GMGARSDKDGVSAIRVYVGNAGAQSVEAIEQAYPLRIDEWSLVADSGGAGRHRGGLAAR
                     RVYRVDYDEATFTVAGERERQVPDGLEGGLPGSCFKCEIERSDGTVETVPARGSHVIVR
                     KGDRVLVQPAGSGGFGKPEDRDQAAIAADLADGYVTAAAARRDYRQAAPDSGSATGKAA
                     V"
     gene            complement(25583..27628)
                     /locus_tag="SFOMI_RS15445"
                     /old_locus_tag="SFOMI_3120"
     CDS             complement(25583..27628)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014071.4"
                     /locus_tag="SFOMI_RS15445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3120"
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="WP_099186188.1"
                     /transl_table=11
                     /translation="MRRVGIDVGGTFTDVVLIDDELDRHWSVKVPTTPADRVIGAIEGF
                     KAILEISAYKSEDIDFVGHGTTMATNMVVEHKGARTALVTTKGFRDILEIRRVSRHDRA
                     DLYDLQFEAPRELVKRRWRLEVDERIDAKGNIAKPLDEEEVKALADQLAGSDIEAVAVC
                     LLHSYTNPAHELRVAEILRERLPDRFITTSHEVNPELMEYERTSTVVMNAMLGPVCSRY
                     IRTFKGALRELGFGGELLFMQSNGGLAHPDFVEARPVVLLESGPAGGVSATTRVTERLG
                     LSNSILGDMGGTTFDVSLIRDSKPELRTSGLLHSYTVRSPTIDIDSVGAGGGSIAWIDV
                     GGGVRIGPESAAADPGPACYGRGGTRPTVTDCNLVLGYIDPDSFLNGTFPLDVEAARRA
                     IEKHLAEPLGTSVLEAARTVRAVANALMAQAMRLMTVERGYDPRDFVYVCYGGAGPVHA
                     IDLASELEIRKVVVPALPGLFSAFGMTVADQSIDRQTSIESELAALDPEALAAMFASLE
                     DEVRADLSSYVSGGADIRVTRRVDCRYAGQPEAMTVDIGEGAVDVAGIRAAFEAAHMRQ
                     WNFIKPDQPIICVNIRARAEAETGWRGTIRSSDGTSDLEPLQTSRVRRLYLGGEMIDVP
                     VFKRGRLRDGDRVHGPAVIEEASSCLVVDTGHVAYLDAFSNLIVEL"
     misc_feature    27649..27664
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    complement(27787..27800)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    complement(27926..27946)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.17"
                     /tool="antismash"
     misc_feature    28077..28097
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            28134..28886
                     /locus_tag="SFOMI_RS15450"
                     /old_locus_tag="SFOMI_3121"
     CDS             28134..28886
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-163). E-value: 1.4e-12. Score:
                     39.8. Matches aSDomain:
                     nrpspksdomains_SFOMI_RS15450_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010219493.1"
                     /locus_tag="SFOMI_RS15450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3121"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_025547191.1"
                     /sec_met_domain="adh_short (E-value: 3.4e-32, bitscore:
                     109.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.5e-36, bitscore:
                     123.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLAGKVAVVTGGSSGIGLATAQAFVEAGAYVYITGRRKAELDA
                     AVAQIGGNVAGIQADSARKDDLERLFRTIAADKRRIDVLFANAGGGAIIPLADVTEGHF
                     DDVFDRNVKGVFFTVQAALPLLVEGASVILVGSTAGSMGNESFSVYSASKAAVRNFARN
                     WILDLKDRHIRVNTLSPGPIRTPALVGLAGPDADQQQALLDRMASLVPLGRVGEPEEVA
                     KVALFLASDDSSYVTGSELFVDGGRAQI"
     aSDomain        28155..28622
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SFOMI_RS15450_PKS_KR.1"
                     /evalue="1.40E-12"
                     /label="SFOMI_RS15450_PKS_KR.1"
                     /locus_tag="SFOMI_RS15450"
                     /protein_end="163"
                     /protein_start="7"
                     /score="39.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGGSSGIGLATAQAFVEAGAYVYITGRRKAELDAAVAQIGG
                     NVAGIQADSARKDDLERLFRTIAADKRRIDVLFANAGGGAIIPLADVTEGHFDDVFDRN
                     VKGVFFTVQAALPLLVEGASVILVGSTAGSMGNESFSVYSASKAAVRNFARN"
     CDS_motif       28161..28226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SFOMI_RS15450_0001"
                     /evalue="4.60E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="SFOMI_RS15450"
                     /protein_end="31"
                     /protein_start="9"
                     /score="19.3"
                     /tool="antismash"
                     /translation="VVTGGSSGIGLATAQAFVEAGA"
     misc_feature    28182..28195
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            complement(28946..29356)
                     /locus_tag="SFOMI_RS15455"
                     /old_locus_tag="SFOMI_3122"
     CDS             complement(28946..29356)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SFOMI_RS15455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SFOMI_3122"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_025547189.1"
                     /transl_table=11
                     /translation="MCEATRELVRQFADHLESGRPEQAFRMLNADGRYILTGTTPASGV
                     YEGVDDLFTRLAPHLSRFTGAPDIKVSDVLVDGDKAFLRASGRAAAAYGTYDQPYYGFF
                     LHAKGDGFAEIVEFLDTVQIEVALFGKKLVSA"
     gene            complement(29401..31527)
                     /locus_tag="SFOMI_RS15460"
                     /old_locus_tag="SFOMI_3123"
     CDS             complement(29401..31527)
                     /EC_number="1.1.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03075.1"
                     /locus_tag="SFOMI_RS15460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SFOMI_3123"
                     /product="PQQ-dependent dehydrogenase, methanol/ethanol
                     family"
                     /protein_id="WP_099186189.1"
                     /transl_table=11
                     /translation="MPCPAVRRKSRWGGFLLLVPLLALPACNRSSGAPTQGRDADWVGY
                     GNGHDEQRFVPVAQIDDKNVGQLGLVWSLDLDEQSALAATPIEVGGTLYFSGAFGHIYA
                     VDARTGRLLWTYDPQANEAAPRDIRRAWATNRGVAYADGRIFVATRDCRMVAVDARTGK
                     LVWQSSFLVPGSNSTSTGAPRAFKGKVIIGNSGSEFGSRGYVTAFDAKTGKLAWRFFTV
                     PGDPAKGFENDAMAMAAKSWSGEWWKYGGGGTPWNAITFDESFNQILIGTGNGGPWNNK
                     FRSNDPKGQDNLFLASVVAVDADSGAYKWHYQYNPNEVWDYKATADIILADIAVQGKTR
                     KVMMQAPTNGFFYVIDRADGKLISAGKIGKVTWADHIDLATGRPVERPGIRGEKGAAII
                     YPDNYGAHNWQAMSYNPRTGLAYIPYMQSGMKYGPALTRAEAVDVDPNEKRISFRIGAA
                     IEPMKDPGDRLDGKGSLLAWDPVAQKVRWRVDYPTSLNAGTLTTGGNLVFQGTNTGKLY
                     AYSATTGERLWSFDTKLGIIAPPISYSVDGRQYLSILVGYGAMGGMGGPGHDQGWKYGL
                     QPRRLLSFALGGKANLPATPPPDFVVHKLDDPRLALDPKRVRTGAKVYAMLTCGMCHGA
                     AAIASGNAPDLRESGVALDRSAFKEILKGGALVSRGMPLFDDLSDREIEDLYQYIRARA
                     RARDTEQAEVRGGL"
ORIGIN
        1 ggcctcattc tcgacattgt agaagaaggc gccgaattcg gcgccggtca gttcgacccc
       61 cgcatcggtg acgatctgga cgagttcctg aagatcggtc ttggccgcca gcgcggagcc
      121 ggcccgattg agtatctcca gcgcgcgccg ctcttcggag atcgcctcct gcgcttccct
      181 gcttttcgtg cgatcgtgca aaatcttcgt gaatccgacc acggaaccgg cctgatcgcg
      241 gatcggggac atttcgccta cggcccatat ctgcgatccg tcgcggcaaa tgcgccaacc
      301 ttccgttccg ccgccacggc cgacggtcag cgcgtcggtc atctcttgtc ggagcgccga
      361 ggcgccctct ccggggggga acaggcgctc cagcgtctcg cccagaacct cagaggcggt
      421 ccagcccagc atccgggacg cgccctcgtt ccaactcgtc acccggcctt cgagatcggt
      481 ggtgacgatc gccgtgccaa ccgcgccatc gacgatctgg cgccattcgt cagcgctgat
      541 cgcgcgcgac ggttctggct ttttcatcga tcccccggga aaaaattctt ctgatgctgg
      601 acgcaaacgc aaaacgcctg aactggttgc agacgggacg gtgggaccgg gccgataatc
      661 tcgatcgaag actcatggca accagatcgc cggtgaagat ttattgcgat gttgaaactg
      721 atttgaggta gcccgtggcc gacaaggatg gcgcagaagc gcccgtcaat cccaacgaag
      781 cgaccggcga gccagccggc gatctggaag acaccagctc ctatagtccg acaggcgccc
      841 gaccgacgca tcactggaag cgatcgaccg tggcggaacc tgggctcgac cagcgcggta
      901 cggtgttctt cgctgccttg cagatgacgc ggatgccgat gatccttacc gatccgcgcc
      961 aggacgacaa tcccatcgtc ttcgccaaca aagcgtttct cgatctgaca ggctatgagg
     1021 aaagcgaagt cttcggccgc aattgccgtt tcctgcaggg ggccgacacc gacagggaaa
     1081 ccgtccgcgc ccttcgcgaa gccgtaaggg cgcaggaagc gatttccacc gaaatcctga
     1141 actatcgccg cgacggcagt cccttctgga acgcggtgtt cgtggcgccc gtctatgatg
     1201 acgacggcac gctcctctat ttcttcgcca gccagcttga cgtcacgcgt cggcgctcct
     1261 ctgaacaggc ttttcgtcag gcgcaaaaga tggaggcgat cggacaactg actgccggcc
     1321 tggcgcatga tttcaacaac ctgctgcagg tggtgacagg caatctcgac atcgtgctcg
     1381 gagacgatct gaacgatgcc cagcgacgga tgctgggcaa tgctgcccgc gctgccgagc
     1441 gcggcgcgag gctgacgcgc cagttgcttg ccttcgcgcg caagacccgg ctcgagccgc
     1501 gccggatcaa catgaacgag ctgatccacg aattcggcga tctgatcgac aataccgtgg
     1561 ggccgcagat caggctggtc accgcgctgg agcgtcggct cccggcggtg cagatcgacc
     1621 ccacgcatct tgagatggcg gtgctcaaca tcctgatcaa cgctcgcgac gcgatgccgg
     1681 gcggcggcac cgtgacgatc gcgaccgagc tttggaagct gaacggcaac gcggcggcgc
     1741 atggccttcc cgaaggggat tatgtcgtat tgagcatccg cgacgaaggc catggcatga
     1801 gcgccgaggt tcgccagcgc gccaccgagc cgttcttcag caccaagggc aaggagcgcg
     1861 gcaccggcct tggcctggca atggtccacg gctttgtgca gcagtcgctc ggccgtctgg
     1921 aaatcgactc cgagccgggg cagggaacga cgatgcggct gctctttccc gtcgcgccgc
     1981 ccgaagaggc cgtgtccggc cccgtgcggc ccatgccagc gccggcgatt tcaggcgatg
     2041 ccggaggaca gacgatcctg ctggtcgaag acagtgacga tgtccgcgcg ctggcgagcg
     2101 agcaactggc tgcgatcggg taccgggtca ttcctgtcgc aagcggcgag gaagcgctcc
     2161 tgaagcttga gaatatcaag gtcgacctgc tcttcaccga tatggtcatg ccgggtggca
     2221 tgagcggcct ggaactggtc gagaagttca acgaactata tccggaaacg ccagtgctta
     2281 tgaccacggg ctataatgag gatctggtcg ccgacatccc gcgcggcacg cggctcgacg
     2341 tgatcggcaa gccctatcgc cgcgaggagc tggcggatcg cgtaaggacg gctctgtcac
     2401 gccgcaccgt cgtcaggcgg gaggaaagtc cgtttggcgc caaggagggg tgatgggctg
     2461 aatccccaca cgccctagaa tgctgattaa gcttgtggca atcctattgg ataggacggt
     2521 atcctcagct agacagcgac catgcggggg ctggacattg cgatcgcggg ctgcgggccg
     2581 tgcggactgg cggcggcgct gctgcttcat cgtgccggac atcatgtaac gctgttcgaa
     2641 cgcttcgata cgcctcgacc catcgggtcc ggcttgatgc tccagcccac gggcatggcg
     2701 gtcttgtttc aattgggatt gctggaggag gctctggcgc ggggcgcgcg ggtcgatcgc
     2761 cttttcggca aggcgggcag gcggatcgtc ctcgacgtcc attatgcagc ccttcgccac
     2821 cgggaaatgt tcggcattgg catccatcgt gccagcctgt tcgcgatcct gcacgaagcc
     2881 gtcctgcagg cgggaatagc cgtccatacc ggccgcacgc tgacggggag cgccccggtc
     2941 gggctgaagc gcgcgctaca ttttgccgat ggagagacga gtggccccta tgatctcgtc
     3001 gtcgatgcgc tgggcacgcg cacagcgctg gcgccgccca cgggccggga actggcctat
     3061 ggcgcgctgt gggcaagcct cgactggccg cagaccgccg cattcgatcc ccacgcactc
     3121 gcgcagcgtt acgagcgcgc cagcatcatg gcgggagtcc tgcccatcgg aacgccgccc
     3181 ggcgcgacga tgcccaaggc tgctttcttc tggtcgctcc gcgcggaccg gctggacgac
     3241 tggcgcgagg ccgggctggc gccatggaag gcgcaggttg ccaagctatg gcccgactgc
     3301 atgccgctgc tcgatcagat tcatgatgct gaccaattga ccttcgcccg ctacgcccat
     3361 cggacccttg cggctccagt gggaccggcg ctggtccata tcggcgatgc ctggcactcc
     3421 gccagccctc agctgggaca gggcgccaac atggcgttgc tcgacgcctg ggcgctggcc
     3481 cagggtttag caaagaagaa tggtgtcgat gaagggattc ggcacgccat tgaactgcgc
     3541 cgtcgccatg tgctgaccta tcaatggctc accgcactgt tcaccccggt ctatcaatcg
     3601 gacagccgtc tgctgccgtt gatccgcgac cgcgtggtcg gccccttgtc caagctctgg
     3661 ccggccaccg ccatacaggc ggcgatggtc agcgggctgg tcggcaatcc cctgccgcca
     3721 ctggggctgg atggcgattg gacggttggg atgcccatgg cggaggctgc atgaacgatg
     3781 cgtcgagcga tagcgacggc cccatcatcg tcttcgacgc catgtgcgtg ctctgctcgg
     3841 ccaatgccgc tttcgtgctg cgccatgacc gcgccggtcg ctttcggctc gcgtccatgc
     3901 aaggtgacat tggggccgcg ctcaaccgcc ggttcgggat cgacccggcc aatccggaaa
     3961 gcttgatcgt ggtggaagat ggccgcgcct tgcgggacag cgatgcggtg ctggccattt
     4021 gggcgggtct ggaccgcccc tgggatgggc tggcggcatt ccgtatcgtt ccgcgctggc
     4081 tgcgcgatcc cgtctatcgc tggattgcgc gccatcgtta tcggctgttc gggaagcgat
     4141 cgacctgctg ggtcccgacg acggaacagg cacgccgcat tctgtgagcc ggatcttgct
     4201 ccttggcggc tatggcggct ttggcgggcg catcgcgcgg cgtctcgccg ccgcagggca
     4261 tgaggtgctg gtcgctggac ggtccatcga caaggcccgc gccttttgcg gggatgcgcc
     4321 cagcctgatg ccgctgggac tggatcgcag tcggatcgcc accgcattgg aggagcatag
     4381 gccggacatg gtggtggatg cctcaggccc ctttcaggcg atggatcatg ccatcgccaa
     4441 agcctgcatt gctgccgggg ttcactatgt cgacatcgcc gacagccgcg atttcgtgtg
     4501 cggcatcggg gcgttggacg atgccgccag agccgcaggc gtcatcctcc tctccggcgc
     4561 ttcgagcgtg ccggcgctgt cgggcgcggc ggtgcgtcat ctggcgcaag gcatggacag
     4621 ggtgcgcgcg gtcgagatgg cgatcagcgc atccaacaag gcgacggcag gtccggcggt
     4681 ttccgccgcc atagcaggac aggtcggcca gcccctgcgc atctggcgcg gtcagcactg
     4741 ggcgaaagcc ttcggatggc aggagatgcg ttccgtccag ttccgatgcg cgggaacgga
     4801 ggcgatcaca ggtcgcaagg tcgcgcttgt cgatgtgccc gacctcgccc ttctgcccga
     4861 aaggttggcg ggacgcccag ccgtcacctt ccgggcgggt acggaactcc ggttccagaa
     4921 ttgggcgctc tggctagcca gctggctggt gcgttggcgg ctcgtcgcga ctctcgcgcc
     4981 gctcgcgcgc ttccttcacc ctctccaatc cctgacccgg tcgctgggga gcgatcgctc
     5041 cgccatgatc gtgcacctgt tcggtgacgt ggctggccaa aaggtcgagc gccgatggac
     5101 gctgatcgcc gaccggggcg atggcccgga aataccgaca ttgtccgtgg tgcccatcgt
     5161 agcgcgcatc ctgtcgggac aggaagccgc aggcgcccgc gatgccgcag aggcgctgac
     5221 gctgagcgat tatgccgatg ccttcggaaa tctggccatc catcatgata gggcggaact
     5281 gcctgctccg ccgcccctat atgaccgcat catgggtgat cgcttcggac agctcccacc
     5341 ggaggtgcgc gccattcatg atgtgtttcg cgatggcggc gcagcgggcg aagccacggt
     5401 gaccggcgcg tcgaacccgg ccgcggcatt gatcgcgcgg atcgtgggct ttcccaaagc
     5461 cggtactcat cgcctacatg ttcatttcca tgaagccgac gcccgcgaaa gctggacccg
     5521 caattttgga gggcgacgct ttcagagcca cctcagccaa cggggccgct ggcttgtcga
     5581 acgcttcggc ccgttccgct tcgccttcga tcttcccggc gacgctcagg gattgaccat
     5641 ggtcatgcgg cgttggtgga tcggtcccct gcccctgcca acatggcttg ccccgcgttc
     5701 gcccgcccgc gaatgggccg aaggcgggcg cttccatttc gatgtgccca tcgcattgcc
     5761 cctgatcggg cggctggtcc attatcgcgg atggctggaa ccggcgacaa tccgatagca
     5821 gaccacgctt tcgaccactg gctgcaattt ggaacatcga tccttatcgg acgctcagtc
     5881 ttcgattttc attccccagg tgccgaccct ttgctttcgc aaaagtctac ctccttaact
     5941 ggttaaatgc ggaccttttg tcgatcagtt acggtgcaag ctaccgaacc tctagaacgc
     6001 tcgggtgatc ccgatttcag tggcggcgcg gcgatattca tagagggctg tcgtggagat
     6061 attgcgttca taggcgagcc ggacgtacgg cgcgaaacca cgataggcca ggccacggaa
     6121 cgtcgcgccg gtacgggcgc tcatcagcca ttcttgccga cgtgccccaa acaggaatag
     6181 cgcggcatcg gcctcagttc gcctgatgcc agtcgaaaca aacagagtag tatgtccagc
     6241 ctcccgccag ccggtcaacg tcaacccgcc cgccgcagtg gcatagcccg gatcacgcgc
     6301 agtttggcgc gttccagaga atgttacgct ggctcccgca cgtgccgaca gggctcgctc
     6361 gaacgacagg cccagatcgt agatggttcc gtcctgcaaa ttattgcgtg cataggtgac
     6421 gtcactcacg ctcgccgtgg cgacaagctg cgaggtccgg cccagtccat gcagccagtc
     6481 gatggtcacg gcgtcagtat ctgcatagcg ctgtccccca taccagcgcc gggtcggacc
     6541 tgcctaaaca ctcaaccgat cgcgcccatg caaccattcg atcccgatca gagccgaccc
     6601 ggacacatcg ttgaattcat gattgcggta caaattcaca agtccggcga gccttggcac
     6661 gagcgcgaga tccttggcga ggccgatacg tggcttggcc agcaagacgc acgccatgcc
     6721 cggattgcgc gcgcgcatcc tcggaaagtg tgaggggcgc gatgatcgta tcgagtacac
     6781 gcgcctgagt tgctcgattg atattggaat cgggagccaa cgcgagttca aatgtgccgc
     6841 cccatggctt gcgcgaacgc agcgcgcgat cgaatcggcc gacagttacg gccacttcag
     6901 gcggcagccc cgcggcctgg gcctggcgta tctgtctccg ggcgccccca tcatcgccga
     6961 ttgccgccag agcgcgtgca agctccaacc ggacgcgggg cgcgttgggt tgctcgtcga
     7021 gcagagcgcg gaatgcaatg gccgcgtcct gccaacgctc ggcgtcagcg aacatcatcc
     7081 ccttgcgaaa ccgcgcctcc cgcgcgaacc tgcatatccg ggtctctggc gagcgcgtcg
     7141 taaaaggttg ccgcgtcgtc gatctggcct gcggctcgcg cacgatcagc caagccgaat
     7201 agatcgacgg cggaaagatg gtcgatatgc gtctgcgccc gcgcggacac cgccggagca
     7261 gcgaccgcca gcgcgagcgc cagcccaaaa tgtcggatca ctgccgcttc gcagccgcaa
     7321 caccctggat cgtgatcccg gcgcctgccg cgccggtggg cgccgtcacc gagaagggcg
     7381 caacgatttc ctcgccatcg gggccataaa agcgaggggc gaactggccc gtctcgacac
     7441 ccgcgcgtgt caacacgccc gtgacgcctg tgttggtcag ccgtcctgcc acgtcatagc
     7501 tgccgaagtc gatcaccccg ctcccgtccg agggggtgcc cttcatcgcg agcgcgccgg
     7561 tgtagctctg tgcgccaaag tcgacggcaa attgggaagt ccccttcacg tcgtagaaga
     7621 tgttggacgg atattgtcga ccggtcccat agaggatgcc gcgatagctg cccgtgccgg
     7681 tcttgcccgc gagcaatccc gacggcgtcc ccagcccata ggcgccatat tgatcaacgc
     7741 gctgccgtcc tgtgccaaac ggcacagtgg tcgaataatg aacgaagctc gcataggtga
     7801 gtgccagttc gctgttgccg ccgcctggct tgtagagctt cagggtcacg tcctgcgtat
     7861 catagctgct gctgaacgtc ttgcgatatt ccatgaaatt gagatcgctg cccgccacct
     7921 tgtcattgat ggtgaactgc ccgccataca gatcggaggt gggcggtcca aagctgagag
     7981 tctcggcatt ctgctggttt agcccgccaa caaggttgtt gagatactgg acatagaaat
     8041 gttgcgaact ggtaagattg atcagcgtca aattctgagc ctggacggtt gcgtcgcgct
     8101 ggccggtgaa gccccccgcg acggtcatac cgttcccgtt cgcccccgaa aaggcgccac
     8161 ccagttcctc tccattgggg ccatagaagc gcccggcgag aggaccggcg gccgatccaa
     8221 accagccctc attagcgcat tgcccgaaaa ggttccgctg ctcgacgaga gatgtcccgc
     8281 cccggtgaac tcgattccac cgccggacac accctggtcc gttacgagag tcgtctcgtt
     8341 gagatagctg tgggttgcga acacgcccgc agcaaaatcg acgctgaagt cgccttggcc
     8401 ctgaaaagag cgtggctcct gtccgggcgt cgaaaccgcg ccgaatgtat cggtcctgaa
     8461 acccgccacg ccgcttcgcg gcacggtcgc ggcagaagtg ggcaaaccat aggtgaagat
     8521 atagaaatcc atgtcctggc gcgtcccgga cacggcattt tcctgccaga atgccaagcc
     8581 gacatattgg ttcgacttgc tgttggtata aggcgtcgtg gctatcgtca gatagctgcg
     8641 atccgtaccg ccggtcttct gatagatagt ctcaccgttg gcattggact ggatgttttc
     8701 gggtgcgaag cgttggctcc acccatcagc actcacgcta tagcttttgg taccagcgtc
     8761 ataattcact gtgagactgt ttggacggat ttgccggctg atttccgtac tggtggcgag
     8821 gtcgagtcca agcttcatac ccgcagcatc attctggaaa gcctggctga ctttcaggtc
     8881 cgtgatcata ttgttggtag acggaggggg cgcaggcata ttgccaaccc cgccgcctcc
     8941 acacccgccg agcagcaaaa atagcgttac ggccgtgatt ttgtttcgca tgataccccc
     9001 tattccgggc atgcgttaaa caatcatata acaacgtcaa tagtttaacg cctactcgcg
     9061 gaggaaaagg ccccaaatgg cgattactgg atttctgcgc atagtcgggt gatgcttgag
     9121 ggacgcggag ctcacagttg tgcatctcgg gactagccaa atcatgctcc agctatccga
     9181 ccggtcaata gtttacagac aaccccggtg caaacagcag tttatgggat aagaatggac
     9241 gatgccgtag ggccgtcgaa aagatggccg ttcatgttcg ttttcgcgga ttcgcaaagc
     9301 aggaacatta tgtcgaacat tatctgagac caatgcgtct ttccccggtt ttacgccaga
     9361 aaacgacaaa cccctctggc gcccaccaga tgactggaca atcatccaga agatgagcga
     9421 ggaaggcggg ggcaccgaaa taacgatgga tgattttgcg cggcgctttt ccatgcggcc
     9481 ggcaagttat gtggtttctc ggcgccggca ttcagctgcc gctgatagcc ctttgtccgg
     9541 ggaccgctct accatgtcct ctccaacccc atctatatcg gcagatctat gagatgcggt
     9601 gcaggcgaag cggcaggctg gcatcggaac gaagcgtgat cttggcaata gtccgcatag
     9661 cagcctccta accagcatga ttcaggatca tgctgaccgg ccgatatcgc ccagccacgc
     9721 ggtcaagcag cagcggcgct gccgctatca tgtgtctagc atgacactgc ccgcagagga
     9781 tgcagtggcc aaaattcctg cgcttcggct cccggcgcca gagctcgaac aagccgtccc
     9841 agatgcaagc tccggccttc ttactgatca gcgcaccatc ttggcgctac cgcaatccga
     9901 gatccgggcg ctgatccatc gtagcaggcg ggggttgcca ccttcacctg ccgggcgcgc
     9961 acggccccta ctgacccatc cttatcacgc gaaacatcgc tcatatccgc gacagctcgt
    10021 cggcaaatct ttccctcagc cgtttcttgt cgatctttcc cgttgccgtc agggggacgg
    10081 gagcgaatat gaccttgtcg ggcatccacc atttggcgat ttgcgacgcc agatgatcca
    10141 ggatgacctg ctgctgaagt tgcgcgccgt catgtccctc tatgatgagg atcggacgct
    10201 cctcccattg gggatgacgg acgccgatga ccgcggcgac cttcaccccg gcacaggcgg
    10261 ccgcgacatt ctctatgtcg atcgaactga tccactcgcc gcccgatttg atcacatcct
    10321 tgctgcggtc ggtgatccgc aggaagccat gctcatcgat cgtggcgatg tccccggtgt
    10381 cgaaccagcg gtcgtcggat gtggcgtcct tctcgcttcg gaaatagcgc tgcacggtcc
    10441 acggccctct cgcctgcaac ccaccaggcg tggcgccgtc atgcggcagc gccgccccat
    10501 cctctccgac gatgcgcagt tcgacgccga actgcacgcg gccctggcgg gtccagagta
    10561 tctcttcttc cgcttcctga cccagatgcg tgatctgcgg agtcggagtc gatatgacgc
    10621 ccagcgggct cagttcggtc atgccccata cctggcggac cttgacgcca tggcgacgct
    10681 cgaacgtctc cgccatggcg cgcggaaccg cggagccgcc gatcatgatg cggtccaggg
    10741 tgccgctatc ctcgccggtg cgcgccagat ggtccagata catggtccag accgtcggca
    10801 ccccgccgga gaaggtcacg ccttcgtccc tgatgaggga atggaggctc tccccatcca
    10861 tgcggtcgca gggcaaggca agcttgcagc cgttgatcgc cgccatatag ggcatgcccc
    10921 atgccgtcgc atggtacatc ggcacgcatg gcatgatgca gtcgaaggcc gaaaggccaa
    10981 gcgcgcccgg aaggccgttg gcgagcgcat ggagcacgat tgaccgatgg ctgtagagaa
    11041 cgcccttcgg atccccggtg gtccctgacg tatagcatag gacggcggcg ctgttctcgt
    11101 cgaagctcgg ccaatcatag ccgtccgctt cgcccgcgat cagttcctca tagctctcaa
    11161 acccctcatc cggggcgctg gcgagcaata tgaccgcctc caccgccgga atccggtcgc
    11221 gcagcctgtg gatcagcggc aggaagctcc tgtcgacgaa aagaaggcgg ctgcccgcat
    11281 ggttgatcgt gtagacgatc tgatcgtcgg agaagcgcgg gtttaccgtg tgcagaacgg
    11341 cgcccatgcc gggaaccgcg tagaacagct caagatgccg atgggtgttc caagccagcg
    11401 aggcgacccg gtcgccgggc tggatgccgc gccgcgccag cgccagcaca gcctggcccg
    11461 cgcggcggcg cagtccgcga ttgtcatagc gccaggccgg ttccccgacg agacgcgaga
    11521 cgatctcccg gtcgccgtgc gcggtggcgc aatggcgtaa tatgtccccg atcatcaggg
    11581 gagtccgctg catgaggcct tcgatcatgc cttcccctcc cctggcttgt ttttggaccg
    11641 gcgatgctgc tcctgccggc gttcacgcaa tggcggcacg ttattctcca tggttggcgc
    11701 gcgcttttgc cgcgggcgta aggtcgcctg cggtcctccg cctatcttgc cggcgcgagc
    11761 agcgccaaag gcgcctcttc cggattttca taggcgcccg ccgggttcag gccgaagatg
    11821 cagacatggt ccgcgccagc gtcccaatgt tcctgaatcc gggcgcggat ggtccgttca
    11881 tcgccccagg cgacgatcgc gtcgatcagc cggtccgatc cgccgtccgt gaaatcatca
    11941 tcgtcaaagc ccagccgctt ccaattgttg cgataattgg gaaaggttag gttccaggcc
    12001 aaagcccggc gcccggtggc gcgcgcttca tcgggatcgc tttccagcga aaccagaagg
    12061 ttgacgcaca gcagcttgtc cggtcccaat atggcgcggg ccatggcggt atgggcgggc
    12121 ggcgaattat tggtgtaggc gccgtcggca tgggacgccg aaagctcgat catcttgggg
    12181 ccaagcgccg ccaggacggt cagcggccgt tcgctgggca agacggtcga atccattctg
    12241 aagcgttcca tggcttccag ataggccttc atcgtggcga ccggcttcct gctgtaggtc
    12301 tcgccgcgca attcctccac cagttcggga tgcgagacgc caaggccaag gaggaagcgg
    12361 ttgccggatt gttcggccag ggcgatctgg gcgcccctca tcgagacatg atcgcggccg
    12421 tagatgttga cgatgccggt caccatgttc agttcccgcg tgttcgccag catccaggag
    12481 gaatggacca ggctgtcgcg cccggcggac acgtccggca cccagagtgt tcgatagccc
    12541 caattttcaa cgcgctgcgc gaatttcgcc gcttcggcgg cgggcatcaa atccgtgaag
    12601 gcaaagacac cgagcggccc catgcgggag gcaaaggtgg attccgccat aatcagttct
    12661 ccttgctaaa gctgtatctc atcgcgccgg gaaagcgctt cccccccagc cgtcggcccg
    12721 gcaaagcccc gcgcgacagg gcgcgggccg cctcccgaaa tccggcttgt tcgtccctgt
    12781 gcggccccgc aacgggccag cctgcctcac agaaagacga aaccgccgtc gaccatcagg
    12841 cattgcccgg tcatatagtc ggagccggaa gaggcgagga accgcgccac tccggccaga
    12901 tcttcgggaa ccgacgcgcg gcccagcgtg atctggggaa tgagattgtc catcgcctcg
    12961 tcacgctccc gggttagccc ctcggcgcgg aaatccccct ctatgctatc ccaaaggtcc
    13021 gtcttcacga caccggggcc gatggcgttg acggtgatcc catgctgtcc gaacgcgcgc
    13081 gccccgccct gggtcaaggc ggccacggcg aatttgctgg cgccataatg gaccagaggt
    13141 tcgtgacatt gtttcgaggc gatcgacccc gtgttgacga tctttccgcc ctgtccctgc
    13201 tcgatcatcc gggccgcgac ctcctgcatg catatcagca cgctcaggcc gttcaccgtc
    13261 atcatcctgt gccaatcctc ctcggtgatc gagaggaagg gctttccctg agcggtgccg
    13321 gcattgttga acatgacgtc gagcctgccg aattgggcaa tggcctgcgc aatcatggcg
    13381 cgcacgctcg cccggtcggt cacgtccacc ttcacggcga tcgcccggcc gccagcttcc
    13441 tcaatctcgg cggcgacggc ggacgcggcg gcatgatcga tgtccgcaat cgtcaattgc
    13501 gcgccgtcgg cggccagcgc ccgcgccatc gcccggccga tgccgcgccc ggaaccggtg
    13561 acgatgatgg atttggtcga aagatcagag ctcatatttc catcccattt ggacgttgat
    13621 cgtcttcatg cgtcctcggc ttcgcgcatg cgcaacagca tcggaatcac ctcccgccgc
    13681 aaaaccttgc ccgacatgtt atgcggcagc gcctcgacta tccggatcat gccgggcacc
    13741 ttgaccgccg ccagccgggc cgcgcaatgc tcctggatcg ccgcttcgct gggcgcggcg
    13801 cccggcatcg gcacgatggc cgccgccacc atctggccgt gatccgcgtc gggaaggccg
    13861 accacggccg cctgcgccac ataatccagt tcactcaaga cctgctcgac ctcggccgcg
    13921 tagatcggcc ttccgtcccg gttgatgagg tcgctggcgc ggcccaggac atagacatag
    13981 ccatgctcgt cgatgcgggc ataatcgccc gtgcgatacc agccgtccgg cgtgatcgcc
    14041 tttccggtga ggtcgggctc cttccaatag cccatcatca tcgccggccc gcgcccctgc
    14101 gcctcgccca cttcgcccgg cgcgacttcc cgcccgtccg gcccgaggaa gcgcatccgc
    14161 gcgcccggcg cgatcttccc ggccgatccg gtcggcgggg gaacgcccgc cgggtcgttc
    14221 atgacaaggg gccagcattc gaacgccgca taggcatcca gcacgggcgt tccggtgatg
    14281 cggcgccaat cctcgaaaac ggcttcgttg cgcgcctctc cgccggaaat gcagcagcgc
    14341 agatggaagt ccggcaccgc gtcgcgccga tgccaggcat tggcgatctt cacatacatg
    14401 ctggtcgacc ccgcgaagaa ggtgatgcca tgtcccagca tcgcgtccag cacgccatcc
    14461 ggggaaaatt cgcgcatcag atggattctg gcggcgcggg tggtggcggt cagcgagagg
    14521 atgacaagcc ccatcatcca ggaaagcggc acggcgacca ggatcgtgtc ggcagcgtcg
    14581 atccgccaga tgtccgccac accatccgtt ccctccgcga tcgagcggtg cgaatgcgca
    14641 accggcttgg gcacgcccgt cgtcccggag gtatagccga tgacgccgac cgcgtcgcaa
    14701 tcgacctgcg gcaaatcccc ggcgaacggc gcgatgtggg ggatgagttc cgcgttgcag
    14761 acaagatcga agatttccgt gcgcgagcct gtcctgctga cggcggccgc cgcagcggtc
    14821 tggctctccc cttccgcaaa caggaaatgc ggctcggcat tggtcagcgc atagtcgagc
    14881 tcattgggcc ccgtagaagc gtggacgacc gccatcacgc cgcccgcgcg ccacacggcg
    14941 aagctgagta tcaggaactc cgcgcaattg ccgctcatga tgagcacgct ctgccccggc
    15001 gcgagtccgg cggtggtgag ccgccgcgcc agacgctcca cggcccgatc gaaatccgac
    15061 cagaggattt cgcgatcgcc gtcgacgatc gccaccccct gcggaaagga ttgggccgcc
    15121 ctgcgaagat ggtcgcttgc cagattgatc acgatagctg cctttcgaat tgccgatgct
    15181 ctgcatgggc ggggacgccg acgggctcct gctcgaccgc ttcgcccgct gcccgcgccc
    15241 gctcgacctt cgtcgcctcc gccgactgga cgtgccgggc cgccatccac agggcggcca
    15301 ccgcgatcgg caccgccagc aggcccgcca tcagcccggt ggccagactg ccctgcgcgg
    15361 cggaaacctt gccgaccaga taggggccca aggccgaacc cacgagcgtg ctgacaagga
    15421 tataggtgac cgacgccgtt ccgcgcatgc gcggcatgac gatttcctga atggtggcgg
    15481 cgccggccgc catccacatg atgccgacga atatgacggg aaggttcaga aggaagaaga
    15541 tccagggatt gtgcgtcagg cacatgccga tcacgaaggg aaccgggatc accgtggacg
    15601 cgatgccgac atggattcgc cccgccgcgt gccgacgcaa catgatgtcc gacaggcggc
    15661 cgccgacgaa gacgcccgcc atgccgcaaa tggccgccga agcgcccaga accatgccca
    15721 ccgtcgcctt gtcgaccggc agcgaacgca aagccagagg agccgtccag aagcccatgt
    15781 tcagcaccag catggaggag aagccgaagc cgatcgtcgt gtagagaaag gccggcgcct
    15841 tccacgtcag cgcaaaggtc gcgggatcgc gcgcccgcag catctgggcg gcggtgaagg
    15901 cggcatacca tccgatggcg atcgcgatcc attgcatcct gtcgcccgaa gcggcgatca
    15961 gcccccatgc cgccgacgcc acgatcaggg ccgccgcgat gttgaccgca aggactttcg
    16021 gaccggtgcg ggcagcctgg taaaaggtga aaggaggaat gacgctggca atatcgtcga
    16081 acaggcgcag ccagatgtcc ttttccgccg gaggataagt gccgtcggac aaccccctcc
    16141 tcggttcgcg cagggtcgag acgaggatcg cgatcagcag gcccgggaga ccgacgacca
    16201 tgaaggccgc ctgccatccc cgcaggccga agggtccggc ctccccgaag gacgagagcc
    16261 acgaagccac gaccagcccc ccgatcgcga acgccaggcc ctgaccgaga tagaagccgg
    16321 tgctgaagat gcccagcgcc gtcccgcgcc gcccgcgaga gaaccagtcg gataaaagcg
    16381 aataggcgga aggaacggcg gacgcctctc caatgccgac gccgatgcgg gcggcgacca
    16441 actggccgac gctgccggcc aatccgcaaa acaccgtcat catcgaccag atcgagatgc
    16501 agatggacaa taagcgcacc cgcttccacc ggtccgccag acggccgaac ggaaaaccga
    16561 acagggcata gaagacgccg aaagcggttc cgtgcaggaa accaagctcc gcgtcgctga
    16621 gcccgaaatg cgccttgatg tcttcggcca ggatcgagag gatggtgcgg tccatccagg
    16681 tcagggtata gactccgaca agcaccatca gaacataacg ggcataggga ccgtcgaccg
    16741 cattccgttc cgccgcggct ccgcccatga ccctgttgtc cggtgcaagc gatgcgctgc
    16801 tggcttccaa acccgttcct ccttcacccg cccgctcata acgtcgctga agggcgaccg
    16861 gctgcacgac ggcaagccgg ctacccttga acgtcactgg atattatatc gcagcttcag
    16921 gccgatctgc cggccgcgcg aataggagcc gaacgtcgat gtcgaagacc ccacgcccgt
    16981 atagtcgact tccagcagcc gcttgtcagt cagattccgg ccgaacagcg acatcgccca
    17041 gcggccatcc tccggcccga aatcgatatg cgcgtccagt tgggcataac cgttctgcac
    17101 catgcgcgga tcgttgaacg atcccgcatt atatttggtg cgcgcaaaga cggacgcgcc
    17161 ggccgcgatc tgattgccgt tcccgaccgg ctgcacatat tcgacattga aggagcccgt
    17221 ccatttggac gaatagggcg tcggcgtccc ggaaagatcc tgcgcgccgc cgacacagcc
    17281 gggcgccagc cgcgcatttt gcagcgtgtt gcaggctgcc cccacgaagg aaatatattt
    17341 ggcgtccaga taggcgccgt tgaagcccag ccgcaaattg tcggtaacct gataattgag
    17401 gtccagctcg acgccctgcg accgcgcctt gccgatgttc gacacgacca ggttgaagcc
    17461 ctgccgcacc gattgctgca ggccgttaaa ttcctcgcgg aacaccgcga tcgaataatc
    17521 gaggcggttg tcgagcagaa gtccctttat cccggcctcg accatccatg ccttttcgga
    17581 cccgaacccg tcattggccg ggctggtggt ataggtatag tcgaaaccgc cgaccttggc
    17641 ccccttcaca tatttcacat aggccatgtt attgggggag aatttatact gcacgatcgc
    17701 ctgcggctgc cactggcggt cgaccagatg gaaggtgccc atggggaagg cgtgctggat
    17761 tccgccgagc accgccgcaa ggactccgtc cagcgagggg tcgcgcgcgg ccagcagcgc
    17821 ggcgcgcgag gtgtcaagat cgatgttcgg aatgatgcgc gccgcgaaca tgctctgccc
    17881 ggcctttttc cgcgtgtcgg aatagcggac gccgccggac aggctcaact gatcggtcag
    17941 atggtaggtg agatccacga aagccgaaaa gacccggttc ttctgatcga aggtgaagtt
    18001 ccgcgagaaa ggcgtcgccg cggttccggt aagccccagg gcgcccagat tcagttcctg
    18061 gttcgcgtcg atcgccaggg tgtcgcgctg ataatagccg ccgacggtgg cgtccagctt
    18121 gccgaaagtg ccgccaaagc gcagttcctg gctgaactgc ttatagtggg tccattgccc
    18181 gttcacgaat gcgggactgt ggttgatgcc gtcggtgccg tatatcacga cgccgtcgct
    18241 cttccgccat gccgtggtcg aggtcagcgt cccgcccgca atgtcgtaat tgatgtcggc
    18301 ctgataaagt tgcgcttcca gctccgccaa ttcgtcggtg aagaacggcg cgacattggt
    18361 gttgacgtag cgcgtgtcct tgtcgcccac cacgggatag agcgaggtat tgcccaccag
    18421 cggctggttg gtcggcacca gcgtgttgcc gcggtccttg atccggtcaa gctcggcgcg
    18481 cagcacgatg tccagcccgt cgaccggctg cagccgcagc gacggacgta tcgcatagtt
    18541 gcgcgtttcg ggttcgcgtt cgcccttgac cggattgtca tatcgtcccc ggtccagatt
    18601 ctggaaaagc cccgccacgc gcagactcat gccctcgctg agcggaacgg tgacgccggt
    18661 ctgcgcctga aattcgcggc cataaaattc gtagccgatc gaaccgtcag cctcgaattc
    18721 gtcgccgggc ttcttggtcg agatattgag cgcgccggcc gtggcgctgt tgccgaacgt
    18781 cagcacctgc ggccccttca gcacttccac ccgctcgaca tcgaagatcg gaatgcgggc
    18841 ttcctggtcg cggccgtagg agacgttgtc gacgaattta ccgacggctt gttcgaaacc
    18901 cgcattgccg cccgacccga acccgcggat gaccgccacg ctgttcgcgg cgccataggt
    18961 gtagttgaag ctgggcgtga tcttgccgat gtcgatcatc tgcgtgatat tctgccgctg
    19021 caaagtctcg ccgctcaagg cggtgatcgc cacgggaacg tcgcgaaggc tttcggaacg
    19081 cttgcgcgcc gtcacgacaa tgtcgccaac cgatgagccg ccgcccgcgg cctggtccgc
    19141 gcccgccgcc tggggagctt cctgcgcctg caccgccccg gccgccaacg ccacggcgga
    19201 aacccccgcc agtgccttgg ccgccgcgat atgccatttt cccattgcga tcatcctctt
    19261 tcccctcctt atgatgcgcc ggtctcgtcg ccgtcgcgcg cttttcgatg ctgtggctcg
    19321 ggtccgtttc gaaacggatc gccattcagg ccgatccgga caaacgtcct cccggccacg
    19381 ggcagaacaa atttaatata ggtacagaac acgccccttc cgtcatcgcg caccgcgatt
    19441 tcaggatatt ttgaggtcgc gctattcaac gatcttcgac gaagagagat ttctctgctt
    19501 cacgaatatc catggcatgg attttccaca gctatcgtcc atctctcccg tcctggtcct
    19561 ggaggccgat ctgaacttcc cgacatcttt cgggctttat gcgcaatcga cctcttcatt
    19621 atcgattcgt atcttaggac acaggccggc gcgtgtcaat gaaacgtttc atttatgaaa
    19681 agtgacatga tcctgaatgg ccgtcttgcc gatccagtag cggctggccg ccgaatctag
    19741 gtcgggatag ccgaaggata tgccgaaaag catcttgagc gacggatcga tgcccagcac
    19801 ctcgcgggcc gtttccgcga aaaagccgag caaggtctgg ggcacgcccc ccaggccgtg
    19861 ggccgcaagc gaaagcagga acgtctgagc atacatgccc acatcgccgg cgatccggac
    19921 gctgtcgtag aatgacggca tgaacagcag gcaggcatgc ggcgcaccaa agaattcgag
    19981 attccgcagc atcgtcatgc gacgctcgtc gaacgcctcg cgcgcgacgc ccagcgcttc
    20041 gtaataagcg gcggcctggg ccttctggcg gtcgctgtag acgccgtaaa gttcatcata
    20101 tccaaacgga aaatcaggcg tcagccgtcc cgccgcctcc gcctccagca tcgccttgct
    20161 cagctcgtcg cgcttcgcgc cggagacgat atgcaccgac cagggctgga tattggcgtt
    20221 cgatggggca tggcgcgcat catcgaccac cgcctgcatc aacgcgtccg gcacgggcgt
    20281 cggaagaaag gcccgaacgg accgccgttc gcgaacgaca tcgtgaaaca atttgctctc
    20341 atccatcgca agttcacctt attgagacag aagcggatac cgccagacgc cgttcgtcaa
    20401 gcgtctacca gtcgttttcc gaacaaggcg acgtccagtt gaagcgggtc cagaaattcg
    20461 acaagctcgg caaaaccctc gccctcgaca cgcaggtaga aaccgtagaa gggctgggca
    20521 tagggaccat atttgcccgc gccgccggtg ctggacgccc gcaaaaaggc gcgatagccg
    20581 tcgatcatga tttccgagaa cgtcatctgc ggacgcaccg tgaaatgcac gagcaggggc
    20641 gccagccgct ccatcgtgtc gtccgggcca taataggtgc ccgataccgg ggattcgcct
    20701 ataagcgtat acaccgcatc cgcattgagc atgcggtagc aagcttcgaa atccccggcc
    20761 acatcacgct ctatgaagcg atcgaccagt gcgcgggtct tcttctccgc gaccgcccgc
    20821 tcttcgaggc tcagactata atcaagcatg tcatctctcc caaacggccc atggcgggga
    20881 taccgcgcct caccaaatta tgaaacgttt catatctcac tttccagcca tacatcaaga
    20941 cgcgacgcgc atcgtcttgg gcaggcccgc gcgggcgagc tggccgccaa gcgcgccggg
    21001 cggcaacatc gcggcgacgg ccgatcgcgc agccagcagc cgggcgagat cgatcccggt
    21061 atccaccccc atcagctcga acatgaatat gaggtcctcg atcgcgacat tgcccgtcgc
    21121 ccccggcgca tgcggacagc cgcccagtcc gccgagcgac ccatcgaaga tacggatgcc
    21181 cgcccgatag gctgaaaagg cgttggcaag cgccagccca cgcgtatcgt gcaggtggat
    21241 ggcgatgggc aaatcggcaa agcgttccag catcgccgcg ctcaacccgg cgaccgcgat
    21301 cggatcggca tagcccaccg tgtcggctat ggtgatgccg tcgacgccgg cggcggcgac
    21361 ctcttcagcc agccggaggg tcgcctcggg atcgaccctg ccttcgatcg aacagccgaa
    21421 cgcggtcgac aatccgacat cgatcccggg gcgaccatcc ggcggaaggc ttgccagcat
    21481 cgccacgatc tcgcgcaatt ggccaatcga ttcatggggc gtgcggcgga cattggccag
    21541 attatggctt tcgctcaccg agatgacgaa gttgatcttg tcgacgcccg cttcggcggc
    21601 gagctgcgcg cccctgagat tgggcgcgag cgctgtcacc gtcaatccct caaccccccg
    21661 ggcgtagcgg acgatgtcgg ccgcgtcggc aaattgcggc atgagcgtcg cgggtacgaa
    21721 ggagcagacc tccatctccc gcagtccagc cgcgcgttcg gcgtcgatcc aggcttgctt
    21781 ctgcccggtc gtcggaccgg cggccagcat ctgaagaccg tccctaagcc cgacttcccg
    21841 aatgacgaca ggccgaatga cgacagggtc catcgcgctc accgcccctg aaacaccggc
    21901 gggcgcttct cgttgaaggc cgctatcccc tcgcgccggt cttccgtccc gatcaggcgg
    21961 ctataggcct cgacctcaaa gaacagcccc gtccgcaaat ccatctgcag gccaaagcca
    22021 atcgacttct tcgcttgcgc gatcgcgatc ggcgcgttgg cgcaaatcgt cgccgcggtc
    22081 tccagcgcgg ccgccatgat ggccgcgccg ggcatgatct tgttcaccag cccccattcc
    22141 agcgcttcgg ccgccccgaa aatggcgccg ctcaggatga gttccttggc gcggggggcg
    22201 ccgacgatcc gggccagatg ctgcgtgccg ccgccgccag gcatgatgcc ccgcatcact
    22261 tcgggaaagc cgaagcgggc atgatccgcg gcataggcga aatcgcatcc gagcatcagt
    22321 tccagcccgc ccgcaagcgc cgccccattg acgaccgcga tcgtcgggat cgggcagtcg
    22381 ctgatcgcgc gcaccatccg ctcgaacaga taatgctgtt cctgaaacgc cgcatcgtcc
    22441 atgccgttgc gttccttgag gtcggcgccg gcgcagaaga tgcgatcgcc ttcagccgtc
    22501 aggattatgc accgatagag ggacggtttc gcctccagag cgccgaagat ccggacaagc
    22561 tcctcgccca tcctggtgtt cagcgaattg ccgcggcccg cccttgcaag cgtgatgcgc
    22621 agcatatgat cgccgggatg atcgaggcgg acggtttcca gaccgtcgaa gctgagttca
    22681 tgcgccatga tgactccgcg tttccagggg atcgtgcgcg cccagccggg ggccgggccg
    22741 gccgagcggc gggcggcaac tgtcaaaggc gagcggaagg ccgaccgtct ttaactcatt
    22801 gccggaggtg gcgccgatga tgcccaacgc gccgacctgc gcgctgccca tcacctgatc
    22861 gatgctgttc acccggccgc aggggacgcc ggcgccctcc agctccttct ccagattcgg
    22921 tcggttgcgt tcgcagatca tggcctgcag catgggaaga agcgcgcttc ggttgcggac
    22981 gcgcatgtcg ttggtggcga aacgcgggtc gccgcccagc tcgggcgcgc caagcacgga
    23041 acaaagcgaa cggaacaatt tgtcgttgcc cgccgaaatc atcagctctt cgccattgcg
    23101 gcagaagaag gtctgatagg gcacgatgtt ggcattgccc gaaccatgcc tttcgggcgc
    23161 ttcgccggaa ttcagatagt ccgaaatctg gaccgtctgc caggcgagcg cggtttcata
    23221 gagggacgtg tcgatcgtcg cgccgacgcc cgtcttcgac cgctcgatat aggcggacaa
    23281 tatgcccatg cacgcccaca ttcccgtgcc catgtcattc accgagatcg gaatgcggat
    23341 gctgggatcg ccggcgcggc ccagcaggct catcatgccg ctcaccgcct ggatcagcgg
    23401 atcatagccg ggatgatcgc gcaacggccc ggtcgagccg aaagcggtga tgttgcaata
    23461 gatgagcgcg ggcttggccg cgcgcagcgt cgccgcgtcc aggccgacgc gctcgacgat
    23521 gccccgcttg agattctgaa cgacgatgtc ggcttcgccc aggatcagat ccgcgatctg
    23581 cccgaccgac cggctgtcgc gaagatcggc ggtgacgctc tccttgccca gattgacggc
    23641 gtggaacatg atcgccgcgt cgccatggcg caccgaaccc catgcgcggg cgtgatcgcc
    23701 catccccgca ttctcgatct tggtgacggt cgcgccaagc tggcccagaa tatggccggc
    23761 atagggcgcc gacaggctgt ggccgatctc gaccaccttc acgcccgcca gcggaagggg
    23821 acgcgtcatg tgctggtccc ccatcaaacg gctgccttcc cggtcgcgga accgctatcc
    23881 ggcgccgcct ggcgatagtc ccggcgcgca gcggccgccg tcacgtaacc gtcggccaga
    23941 tcggcggcga tcgccgcctg atcgcggtcc tccggcttcc cgaaaccgcc gctgccggcc
    24001 ggttgcacca gaacccggtc gcccttccgc acgatgacat ggctgccgcg cgcgggaacc
    24061 gtctcgaccg tgccgtcgga ccgttcgatc tcgcatttga agcaactgcc cggcaggccg
    24121 ccctccagac cgtcgggcac ctgacgctcg cgctctccgg cgacggtgaa ggtcgcttcg
    24181 tcataatcga cgcgatagac ccgccgcgcg gccaggccgc cgcgatggcg gcccgcgccg
    24241 ccgctgtccg ccaccaggct ccattcgtct atgcgcaacg gataggcctg ctctatggcc
    24301 tccaccgatt gcgcgcccgc attgccgaca tagacgcgga tcgcgctcac gccgtccttg
    24361 tcactgcgcg cgcccatgcc gcccgcatgc acgtcgaaca ggctggcgaa gcgccggccg
    24421 gtccgcgcca cccgatcctc atccggatcg gaaccggcga agattcccgc gcacgccgcg
    24481 cagttgctct gcgccgtgac gcgctggggc accgcaggcg cgagggcttt cagcagcatg
    24541 tcgatcaccc gcggcgacgt ttccgtcacg ccggacacga cggaggcggg aaagctgcag
    24601 ttgaggacgc tgccttccgg cgcgatcacc ttcaccggcc gatagcagcc ctggttgatg
    24661 gggatcatgt tgtcggtgat cgccttcacc gtgaaccagg tgctgttgta ggtgaccgac
    24721 aaggggcagt tgatgccgcc gcgcacctgc gctccgctgc cgctatagtc gaattcgatc
    24781 gtgtcgccct gcttggtgat cttgacccga atagggatca agggccgctc gccgtcgacc
    24841 tcgtagacgg cgtcgatctc atcctcgccc agatacacgc catcgggcat cgcttcgagc
    24901 gcctggcgca tcagcgcctc ggaatggtcc agcgatcgcg acatggcgga cttcagggcg
    24961 tcggcgccat agcgctcgac cagagtcaat atgcgctggc cgccgacgaa gcagccggca
    25021 tattgcgcct gcatgtccag cagccgcgtc tcgggatcgc gcgtattttg caggatcagg
    25081 gtcttcacat cctcgaccac ccggtcgtcg cgatagagcc ggacgggagg aatgcgaaca
    25141 ccctcgccaa aaatgtccca ggtctccgcc gcgaagctgc cgggggactg gccgcctatg
    25201 tcgctccaat gccccttggt catcacatag gcgacgatcc tgtcgcccgc gaagacgggt
    25261 ctggtgaact gcacgtccgg gtgatgattg ccgcccccca gatagacgtc gttgctgatg
    25321 atgacgtcgc cgggccgcag attgtccgcg ccgatcgcct ggacggtggc cttggtcgag
    25381 atgaccgccg cgccgagcat cgtgggtatg tcattgccct gcgcgaccag ttgcatctca
    25441 tcgtcgaaga tcgcggccga tgcgtccccg ccggaatgga tgatggggct tcccgccgtg
    25501 cgggtcatgg cgatcttcat ctcgcgcgcg atcgcataca ggctgctgcg gatgatttcg
    25561 taggttatgg tatccatcgc tgtcagagct ctacaatgag gttgctgaag gcatcgaggt
    25621 aagccacgtg cccggtgtcg acgacgaggc aactgctcgc ttcctcgatc acggccgggc
    25681 cgtgcacccg gtcgccgtcg cgaagcctgc cgcgcttgaa gacgggaacg tcgatcatct
    25741 ccccgcccag atagaggcgg cgcacgcgcg aagtctgcag cggttcgaga tcggatgtcc
    25801 cgtcgctcga ccttatggtt ccgcgccaac ccgtctccgc ttcggcgcgc gcccggatgt
    25861 tgacgcagat gatcggctga tccggcttga tgaaattcca ctgccgcata tgcgcggcct
    25921 cgaaagcggc gcggatgccc gccacgtcca ccgcgccttc cccgatgtcg accgtcatcg
    25981 cctccggctg accggcatat cggcaatcga cccgccgcgt cacccggatg tcggcgccgc
    26041 cgctgacata ggatgacagg tcggcccgca cctcatcctc gagcgaggcg aacatcgccg
    26101 ccagtgcttc gggatcaagc gcggccagtt cgctctcgat cgaggtctgc ctgtcgatcg
    26161 actgatccgc gacggtcatg ccgaaggcgc tgaacagacc cggcaacgca ggcacgacga
    26221 ccttcctgat ctccagctcg ctggcgaggt cgatggcgtg gacagggccg gcgccgccat
    26281 agcagacata gacgaagtcc cgcggatcat agccccgctc gaccgtcatc agccgcatcg
    26341 cctgcgccat caaggcgttg gccaccgccc ggacggtccg cgctgcctcc aggacggagg
    26401 tgccgagagg ttcggcaaga tgcttttcga tcgcccgccg cgccgcctcg acatccagcg
    26461 ggaaagtgcc gttcaggaag ctgtccggat cgatatagcc aagcacgagg ttgcagtcgg
    26521 tcacggtcgg ccgcgtgccg ccgcgcccat agcaggccgg gcctgggtcc gccgccgcgc
    26581 tttcggggcc gatgcgcacg ccgccgccca catcgatcca ggcgatggac ccgccgccgg
    26641 cgccgaccga gtcgatatcg atcgtcggag accgaacggt ataggaatga agcaggcccg
    26701 aagtgcgaag ctccggcttg ctgtcgcgga tcagcgacac gtcgaaggtc gtgcccccca
    26761 tgtcgcccag gatcgagttc gaaaggccaa gccgctccgt cacgcgggtg gtcgcgctca
    26821 cgccgcccgc aggcccggat tcgagcagca cgaccggccg cgcctccacg aagtcgggat
    26881 gggccaggcc gccgttcgac tgcatgaaca gcagctcgcc gccgaagccg agttcgcgta
    26941 gcgcgccctt gaaggtgcgg atatagcggc tgcacaccgg acccagcatc gcgttcataa
    27001 cgacggtgct ggtgcgctca tattccatca gttccggatt gacctcgtgg gaggtggtga
    27061 tgaagcgatc cggcagcctc tctcgcaata tctccgccac gcgcagttca tgcgcgggat
    27121 tggtgtagga gtgaagcagg cacacggcga cagcctcgat gtccgatccg gcgagctggt
    27181 cggccagcgc cttcacctcc tcctcgtcca acggcttggc gatattgcct ttggcgtcga
    27241 tgcgttcgtc gacctccagc cgccagcgcc gtttgaccag ttcgcggggc gcctcgaact
    27301 gaagatcgta cagatcggcg cgatcatgcc gcgacacccg gcggatctcc aatatgtcgc
    27361 ggaacccctt ggtcgtcacc agggcggtcc tggccccctt atgctcgacc accatgttgg
    27421 tcgccatggt cgtgccatga ccgacgaaat cgatgtcctc gctcttatag gcgctgatct
    27481 ccaggatcgc cttaaaaccc tcgatcgccc ctatgacgcg gtcggcgggc gtggttggga
    27541 ccttcaccga ccagtgacgg tccaactcat cgtcgatgag aacgacgtcc gtgaaggttc
    27601 cgccaacatc gatacccact cgcctcatgc caacatcctc agttgaattc gaatttcttt
    27661 ttgcgccgat cggacgagac catcttacac ctaaccgctg tctccgccgc cccgcggcaa
    27721 gaagcccatt ggaatcttcc cgctatccgc gctgctcctg cccctaccgc accccatggc
    27781 gactgtcaat gaaacgtttc atatttattg tggcgtttgc atgaagcccg gctcccgcat
    27841 gcccttcggc cgccgttatt ctgggagaag caccctatcg ctcgcgccga agccgacggg
    27901 aagcggatgc ggagcatttt aatatgaatc gtttcattga cactatgcca tgcatgccta
    27961 tatcccgtga tccagggaat gcgcccggcg cgggaccgga tatttctccc tcccttgcag
    28021 acgatccaat cgcggagacg ttccgtcacc catctgcgga gatcggcgcc ggacctttct
    28081 tgtcgcgcag cccattaatg gcggctttga ccgccgcgaa cggagaagaa ggcatgagca
    28141 aattggccgg aaaggttgcg gtcgtcacgg gaggaagcag cggcattggc cttgccaccg
    28201 cgcaagcctt cgtcgaggcg ggcgcctatg tctatattac cggccgccgc aaggccgaac
    28261 tggatgccgc ggtggcgcaa atcggcggga atgttgccgg catccaggcc gactcggccc
    28321 ggaaggacga tctggaaaga ttgttcagga cgatcgcggc ggacaagcgg cggatcgacg
    28381 tgctgttcgc caatgccggc ggcggcgcaa tcatccccct cgcggacgtg accgaagggc
    28441 atttcgacga tgttttcgac cgcaatgtca aaggcgtgtt cttcaccgtc caggccgcct
    28501 tgcccctgct ggtggagggc gcgtccgtca tcctggtggg atcgacggcg gggagcatgg
    28561 gcaatgagtc gttcagcgtc tacagcgcca gcaaggcggc cgtcagaaat ttcgcccgca
    28621 actggatatt ggacctgaag gaccggcata tccgggtcaa tacgctcagc cccggtccca
    28681 ttcgcacccc tgccctggtc ggactggcag gccccgacgc cgatcagcaa caggccctgc
    28741 tggaccgcat ggccagcctg gtgccgctcg gccgcgtcgg ggagccggag gaagtggcga
    28801 aagtggccct cttcctcgcc tccgacgatt cgagctacgt caccggctcg gagcttttcg
    28861 tcgatggcgg gcgcgcccag atttagccgg ggcggccctt ggcaaagcgc gcaggcggca
    28921 tatccgcctg cgcctgctcc atcctctatg ccgacaccag cttcttgccg aaaagcgcga
    28981 cctcgatctg caccgtgtcg agaaactcga ctatttccgc aaagccatcg cccttggcgt
    29041 gcaggaaaaa gccgtaatag ggctgatcat atgttccata ggcggccgcc gcgcgcccgg
    29101 acgcgcgcag aaatgccttg tcgccatcca ccagcacgtc cgagaccttg atgtccggcg
    29161 cgcccgtgaa gcgcgaaagg tgcggcgcca ggcgggtgaa aagatcgtcc accccctcat
    29221 aaacgcccga cgcgggcgtc gtgcccgtca ggatgtagcg cccgtccgca ttgagcatgc
    29281 ggaaggcctg ctcaggccgt ccggactcaa gatgatccgc gaattggcgg accagttcac
    29341 gcgtcgcttc acacatatcg ccatctcctt gttcgccccg aaagccgttg ccgtgcaatc
    29401 tcagagcccc cctctcacct cggcttgctc cgtgtcccgc gcacgcgcgc gggcgcggat
    29461 atattggtag agatcctcta tctcccggtc cgaaaggtcg tcgaacagag gcattccccg
    29521 cgagacgagc gctccgcctt tcagaatctc cttgaatgct gaccggtcca gcgccacgcc
    29581 cgactcccgc aaatccggcg cgttgcccga agcgatcgcg gcggcgccgt gacacatgcc
    29641 acatgtcagc atggcgtaga ctttcgcccc ggtccgaacc cgtttcgggt cgagcgcaag
    29701 gcgcggatcg tccagcttat gcaccacgaa atccgggggc ggcgtcgcag gcaggttcgc
    29761 ctttccgccc agggcgaagc tcagcagccg cctcggctga agcccatatt tccagccctg
    29821 atcatggccc ggaccaccca tgccgcccat ggcgccatag cccacgagga tagacagata
    29881 ttggcgaccg tccaccgaat agctgatggg cggagcgata atgcccagct tggtatcaaa
    29941 gctccaaagt ctttccccag tcgtcgcgga ataggcgtat aattttcccg tattcgtgcc
    30001 ctggaaaacg agattgcccc cagtcgtcaa cgtaccggcg ttgagcgaag tcggataatc
    30061 cacgcgccat cgcacctttt gcgcgaccgg atcccaggcc agcagcgacc ctttaccgtc
    30121 cagccgatcg ccgggatctt tcatgggctc aatggcggcg ccaatgcgga agctgatccg
    30181 cttttcgttc ggatcgacgt ccacggcctc cgccctggtc agcgcagggc catatttcat
    30241 gcccgactgc atatagggaa tataggccag gccggtccgg ggattatagg acatggcctg
    30301 ccaattatgc gcgccgtaat tgtccggata gatgatcgcg gccccctttt cgccgcgaat
    30361 gccgggccgc tcgaccggcc ggccggtggc cagatcgata tggtcggccc aagtcacctt
    30421 tccgatcttc ccggccgaaa tcagttttcc gtcggcgcga tctatgacat agaagaaacc
    30481 gttggtcggc gcctgcatca tcaccttgcg cgtcttgccc tgcacggcga tgtcggccag
    30541 gatgatgtcg gcggtcgcct tataatccca aacctcgttg ggattatatt gatagtgcca
    30601 tttatatgcc ccgctatccg catcgacggc gacgaccgac gccaggaaca gattgtcctg
    30661 gcccttggga tcattcgatc ggaacttgtt gttccagggg ccgccattgc cggtgccgat
    30721 cagtatctga ttgaagcttt cgtcaaaggt gatggcgttc cacggcgtgc cgccgccccc
    30781 atatttccac cattcccccg accagctttt cgcggccatg gccatcgcat cattttcaaa
    30841 ccccttcgcg gggtctccgg gcacggtgaa gaagcgccat gcgagcttgc ccgtcttcgc
    30901 atcgaatgcg gtcacatagc cccggcttcc gaattccgat ccgctgttgc cgatgatcac
    30961 cttgcccttg aaggcccgcg gcgcgccggt gctggtcgaa ttgctgccgg gaaccaggaa
    31021 gctgctctgc cagacgagct tgccggtccg cgcatcgacc gccaccatcc tgcaatcgcg
    31081 ggtcgccacg aaaatcctgc cgtccgcata ggccacgccg cgattggtcg cccatgcgcg
    31141 ccgaatatcg cgcggcgccg cctcattggc ctgcggatca taggtccaca gcagtcgtcc
    31201 tgtccgcgca tcgacggcat atatatggcc gaaggcgccg ctgaaataga gcgtcccgcc
    31261 cacctcgatc ggggtcgccg ccagcgccga ttgctcatcc agatcaagcg accagacgag
    31321 tccaagctgg ccgacattct tgtcgtcgat ctgcgcgaca ggcacgaaac gctgctcgtc
    31381 atgcccattg ccatagccga cccagtcggc atcgcgcccc tgggtcggcg cgccagacga
    31441 gcggttgcag gccggcaagg ccagcagcgg gacaaggagc agaaagccgc cccatcggct
    31501 ctttcgacga acggctgggc acggcattaa tatccccttt ccccatgact gaagcatagg
    31561 ccgcatccgc gagccagacc ggcgccgcag gcagacggcg cgccagcatg ccttcagcgg
    31621 cacgccggcc cgttcaatgg attgcagcgc cttcgccgtc accgacgcct gagcaagaac
    31681 tccggcggca aggcgccggc ggatgcgggc gaaaggggca ttgccggccg gggaaacggc
    31741 tctaccccgg acggtaggcc gcgttcaggc gcccgccatg gtccagacgt cccgatcatc
    31801 ctccggcggc acgaccgcgg cgccatacat tttggtcgcc atttcgatcg gatcgttcca
    31861 ttcgatgatc tcg
//
