LOCUS       NZ_NUOG01000013        23483 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Bacillus sp. AFS033286 AFS033286_82_A2_Contig24_140604, whole genome
            shotgun sequence.
ACCESSION   NZ_NUOG01000013
VERSION     NZ_NUOG01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. AFS033286
  ORGANISM  Bacillus sp. AFS033286
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 365820)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 365820)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.73x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002583065.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 14:02:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,319
            CDSs (total)                      :: 5,247
            Genes (coding)                    :: 4,997
            CDSs (with protein)               :: 4,997
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 250
            CDSs (without protein)            :: 250
            Pseudo Genes (ambiguous residues) :: 0 of 250
            Pseudo Genes (frameshifted)       :: 83 of 250
            Pseudo Genes (incomplete)         :: 197 of 250
            Pseudo Genes (internal stop)      :: 59 of 250
            Pseudo Genes (multiple problems)  :: 74 of 250
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:15:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23483
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NUOG01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23483
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..23483
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23483
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[8244:13483](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8245..13483
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            <1..828
                     /locus_tag="COE07_RS08250"
                     /old_locus_tag="COE07_08250"
     CDS             <1..828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002110711.1"
                     /locus_tag="COE07_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08250"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_141555249.1"
                     /transl_table=11
                     /translation="RNKKISYIEIVPKQKGRFFEVHYTYEMHVSQMKKPSTTTSNALSC
                     DLGVDRLVSCATNTGDTFLIDGKKLKSINQYFNKMIRNLQQKNMENGLSKRVVTNQMAA
                     LWHKRERQINGYISQTVGLLFKKVKACNIDTVVVGYNAGWKQKSDMGKKNNQKFVQIPF
                     HKLVAAIENKCVKEGIRFLKQEESYTSKASFLDKDPVPVWSKDDRTQYRFSGKRITRGL
                     YQSKAGTCIHADINGALNTLQKSRVVELDDNLKVKTPILLEVQKRKAVASRIA"
     misc_feature    complement(954..967)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.52"
                     /tool="antismash"
     gene            <1116..1223
                     /locus_tag="COE07_RS08260"
                     /old_locus_tag="COE07_08260"
                     /pseudo=""
     CDS             <1116..1223
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="COE07_RS08260"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08260"
                     /product="metallophosphoesterase"
                     /pseudo=""
                     /transl_table=11
                     /translation="HEEQNTAMIVSRGLGNSIIPQRIFNRPELIVVQLN"
     gene            1437..1688
                     /locus_tag="COE07_RS08265"
                     /old_locus_tag="COE07_08265"
     CDS             1437..1688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="COE07_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08265"
                     /product="hypothetical protein"
                     /protein_id="WP_000548620.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTIILPLQQLVIEYSLDVARIRKYMNLKT"
     gene            1874..2599
                     /locus_tag="COE07_RS08270"
                     /old_locus_tag="COE07_08270"
     CDS             1874..2599
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001187059.1"
                     /locus_tag="COE07_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08270"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_088229130.1"
                     /transl_table=11
                     /translation="MEQPSIILRTVSKSFGKKEVLHNLSLQVEKAEIFGLVGPSGSGKT
                     TLIKMIAGINEATKGEVLVCSTSMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKRKKERINEVFELVQLSEHMKKPVQQFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGNLVAVGTPEELKK
                     RVSSGRIEDVFLLEEVVES"
     gene            2596..3615
                     /locus_tag="COE07_RS08275"
                     /old_locus_tag="COE07_08275"
     CDS             2596..3615
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="COE07_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08275"
                     /product="ABC transporter permease"
                     /protein_id="WP_098252112.1"
                     /transl_table=11
                     /translation="MRVNGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYI
                     PHIAVVDVPAPIVKAMKNQDASIYEYEKEKAYSELEKQKVDAVIHLENGKMKLLLEGSD
                     SSKNRAVLQVLQKSTEKNDVSIMKPEVEYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVAGYIIGFGIFAFIQSIIIVSFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQVFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFNEIALDLTVLLLFSLLFAVGNVFALKKHRKI"
     gene            3640..4293
                     /locus_tag="COE07_RS08280"
                     /old_locus_tag="COE07_08280"
     CDS             3640..4293
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168189.1"
                     /locus_tag="COE07_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08280"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_088229132.1"
                     /transl_table=11
                     /translation="MEKDWLEELVAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKSEYESYEGLL
                     KVVIHNRFEFAKKHFPMIKILIQEVPFQPELKAEIQQLIETELFSHFKKLIVKFQEKGE
                     IIEMPPSSVLRLTLSAVLGLLLTRFLLLPEEKWEDKVEIENTIQFILYGLTPRR"
     gene            4298..5266
                     /locus_tag="COE07_RS08285"
                     /old_locus_tag="COE07_08285"
     CDS             4298..5266
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="COE07_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08285"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_098840933.1"
                     /transl_table=11
                     /translation="MRQFAKPKIVVSKCLEFDACRYNVEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGIPRETIRMVEENGIKRLVQPSTREDVTGKMEQFSKDFLQTISDVDGFILKN
                     RSPSCGTRDVKIYAGFEKAPVKGKGAGLFGGAVIKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKRNKNMKDLVSFQSDNKYLFMAYNQVKQKELGRIIANHKNEKLEAVFD
                     KYEKSLYELFMRTPRYTSNVNVCEHIFGYFKTKLKKQEKDHFFDLIQKYIEKKVPLSSL
                     LAILKSWALRFDEKYLLRQTYFEPYPEALVEISDSGKGRDY"
     gene            5483..6628
                     /locus_tag="COE07_RS08290"
                     /old_locus_tag="COE07_08290"
     CDS             5483..6628
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="COE07_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08290"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_088229134.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.3e-40, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.1e-27, bitscore:
                     88.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.3e-58, bitscore:
                     190.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAVNGVEDNGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIILDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            6644..7981
                     /locus_tag="COE07_RS08295"
                     /old_locus_tag="COE07_08295"
     CDS             6644..7981
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="COE07_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08295"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_098840934.1"
                     /sec_met_domain="RimK (E-value: 7.6e-08, bitscore: 26.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.9e-07, bitscore:
                     25.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.3e-11,
                     bitscore: 39.0, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.9e-10, bitscore:
                     34.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCKEEGIVFIG
                     PSEEIITKMGSKIESRLAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEIAVQAAKALGYSNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLSFTQDDVKRMGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNVRIDHFLENHVTITPFYDPMIAKVIAHGETREEAISK
                     LHEALEELKVEGIKTNTPMLLQVLEDEVFKDGIYTTGFVTKQLVKK"
     gene            8008..8223
                     /locus_tag="COE07_RS08300"
                     /old_locus_tag="COE07_08300"
     CDS             8008..8223
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="COE07_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08300"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_002056745.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIVSE
                     EAGTVMKINVQEGDFVNEGDVLVEIE"
     gene            8245..9156
                     /gene="mvaB"
                     /locus_tag="COE07_RS08305"
                     /old_locus_tag="COE07_08305"
     CDS             8245..9156
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="COE07_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08305"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_088229136.1"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-48, bitscore:
                     160.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISTAAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVERVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            9161..9949
                     /locus_tag="COE07_RS08310"
                     /old_locus_tag="COE07_08310"
     CDS             9161..9949
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 7.3e-76. Score:
                     246.6. Matches aSDomain:
                     nrpspksdomains_COE07_RS08310_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="COE07_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08310"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_088229137.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKVSLNRERQANSLSLALLEELQTILTQI
                     SEESNTRVVILTGAGEKAFCAGADLKERATMNEEQVRHAVSMIRSTMEMVEQLPQPVIA
                     AINGVALGGGTELSLACDFRIASDNASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISSQEAKEYGLVEYVVPAERLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRVEGLQAFKEKRQPMYKGE"
     aSDomain        9203..9922
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_COE07_RS08310_ECH.1"
                     /evalue="7.30E-76"
                     /label="COE07_RS08310_ECH.1"
                     /locus_tag="COE07_RS08310"
                     /protein_end="254"
                     /protein_start="14"
                     /score="246.6"
                     /tool="antismash"
                     /translation="HVVKVSLNRERQANSLSLALLEELQTILTQISEESNTRVVILTGA
                     GEKAFCAGADLKERATMNEEQVRHAVSMIRSTMEMVEQLPQPVIAAINGVALGGGTELS
                     LACDFRIASDNASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISSQEAKE
                     YGLVEYVVPAERLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRVEGLQAFKEK"
     gene            9952..11493
                     /locus_tag="COE07_RS08315"
                     /old_locus_tag="COE07_08315"
     CDS             9952..11493
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012094296.1"
                     /locus_tag="COE07_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08315"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_088229138.1"
                     /transl_table=11
                     /translation="MLDQKQQTNSFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQNGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGSRTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPSNYLEKTPLISPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRVIDEGSFFEVKKLFAQELITGLARIDGKPIGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIIVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            11543..13483
                     /locus_tag="COE07_RS08320"
                     /old_locus_tag="COE07_08320"
     CDS             11543..13483
                     /NRPS_PKS="Domain: AMP-binding (98-521). E-value: 6.4e-83.
                     Score: 270.5. Matches aSDomain:
                     nrpspksdomains_COE07_RS08320_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="COE07_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08320"
                     /product="AMP-binding protein"
                     /protein_id="WP_098252113.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-89, bitscore:
                     295.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLFSWMKSLGYEDYEAFYNKSISETAWFW
                     GEAEKAVGYQWMERYTEVLDLENGTPFAQWYTGGTCNVVESVLSRWIADDEMKRQPALM
                     YEGENGTSKSYTYEELDSWVSRVANGLKQAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFAADAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHSGNDFTPHNYDFSWSTLEKEKPFVHAEEMNSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVVYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNDVIEAAAIGVPDDVKGEVCHCFVVLRDGVTFTGELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     aSDomain        11837..13105
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_COE07_RS08320_AMP-binding.1"
                     /evalue="6.40E-83"
                     /label="COE07_RS08320_AMP-binding.1"
                     /locus_tag="COE07_RS08320"
                     /protein_end="521"
                     /protein_start="98"
                     /score="270.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RQPALMYEGENGTSKSYTYEELDSWVSRVANGLKQAGIEKGDRVT
                     IYMPMIPETVVAMLAVMKIGAIISPIFSGFAADAVMTRVQAAGSKMIITADGFSRRGKI
                     VSLKDEVDKACEHCPTVEKVVIVRHSGNDFTPHNYDFSWSTLEKEKPFVHAEEMNSDDP
                     LMLIYTSGTTGKPKGTVHTHAGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLF
                     GSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSL
                     KSLEVFASTGEPWNPDPWMWLFETVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPISF
                     NASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWV
                     HGDWVVYDGEQYIITGRSDDTLNI"
     CDS_motif       12329..12385
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_COE07_RS08320_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="COE07_RS08320"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       13076..13138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_COE07_RS08320_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="COE07_RS08320"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     gene            complement(13675..13911)
                     /locus_tag="COE07_RS08325"
                     /old_locus_tag="COE07_08325"
     CDS             complement(13675..13911)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002119551.1"
                     /locus_tag="COE07_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08325"
                     /product="hypothetical protein"
                     /protein_id="WP_098252114.1"
                     /transl_table=11
                     /translation="MPCVLPGLTRPVCLTIVYNILSGTLISSSVSCGECEQEVGFDYVS
                     KNLTIVMPFTIEGALTFNDKFLASCITTNITQT"
     misc_feature    complement(13879..13893)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.42"
                     /tool="antismash"
     misc_feature    14676..14689
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.13"
                     /tool="antismash"
     gene            14770..15084
                     /gene="exsK"
                     /locus_tag="COE07_RS08335"
                     /old_locus_tag="COE07_08335"
     CDS             14770..15084
                     /codon_start=1
                     /gene="exsK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535706.1"
                     /locus_tag="COE07_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08335"
                     /product="exosporium protein ExsK"
                     /protein_id="WP_098840935.1"
                     /transl_table=11
                     /translation="MGYRYSNSKKKCTCKQDDCWDAFEECKKEQEEQNKKCDCCCVQGI
                     RDELKKLVNRAVRINTGSNNYAGTVSSVTCDVVKLANSAGVVTVIISVCKIEAIEPLLT
                     "
     gene            15204..15743
                     /locus_tag="COE07_RS08340"
                     /old_locus_tag="COE07_08340"
     CDS             15204..15743
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002007691.1"
                     /locus_tag="COE07_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08340"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_098357552.1"
                     /transl_table=11
                     /translation="MVHERRMELIKLEPFKRVDFKQLINWIHSEEFLIQWSGNAFIYPL
                     DEQQLHKYIESINTLAFKVIDEETLNVIGHISLGQIDNINKSARIGKVLVGDTKMRGRS
                     IGKHMMKAILYIAFEELKLHRVTLGVYDFNTSAILCYEKIGFVKEGLLRESKKVGDTYW
                     NLWEMSMLEYEWDNKK"
     gene            <15791..16035
                     /locus_tag="COE07_RS08345"
                     /old_locus_tag="COE07_08345"
                     /pseudo=""
     CDS             <15791..16035
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288863.1"
                     /locus_tag="COE07_RS08345"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="COE07_08345"
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="FHIVDIAYSWICDLKGSR"
     gene            complement(16086..17102)
                     /locus_tag="COE07_RS08350"
                     /old_locus_tag="COE07_08350"
     CDS             complement(16086..17102)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="COE07_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08350"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_098357551.1"
                     /transl_table=11
                     /translation="MQFLKKITVLLLSFLITALIVLYFYLYVNGPVIQAKSAILIDANS
                     GEVIYKKNEETLIQSTTLSKLMTEYIVLEQLNNGKIQLDETVKISNEVFQVETSPIQIT
                     SKDKTTVRDLLYVLLLTGNNRSALALAEHIGGNEDSFTTLMNEKAKQLQLSQSSPFLNS
                     TGVNQDTNEQPSTTAIDAAKLATQLVKDFPDVLNITKLTSYQFTFKDFQVFNTNKMIYS
                     LNKNIKLQGVDGLQTSFSTNGNYSFVGTAKRGDTRLISVVLEADEENSTFIETKKLLQY
                     GFDPSSYSALQAFKDALTSWSILLQFKNLIIQTMIIFFIITILMFLHIRQKKSEDFN"
     misc_feature    17275..17293
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 25.44"
                     /tool="antismash"
     gene            complement(17285..18442)
                     /locus_tag="COE07_RS08355"
                     /old_locus_tag="COE07_08355"
     CDS             complement(17285..18442)
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243314.1"
                     /locus_tag="COE07_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08355"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_088229144.1"
                     /transl_table=11
                     /translation="MRNEAFDILKDIPKWKIIFWLLLAITLTPITELIIYRLITSVIES
                     SLTLSELSKEFIRIFGYEKYKGLKESLWMMIVSYLFLFSIFSSYLYIFYRHERKMYYET
                     CIKKMIEEIRYIASGNFNHKVSIVNHNYLEELATGVNQIVEQLKVSIDEERQAEQAKSE
                     LITNVSHDLRTPLTSIVGYVNLIQHDNYRDEVELRHYIQVIYDKVTRLNALMNDLFEYT
                     RVQNKELSLYSAPIDIVELLGQLTVQFRIQVQEANIECRPSFPSQKLMVLADGDKLVRV
                     FENLIINAITYGNDGGYIDLTAYESNNMITIDITNYGQPIPSTDLPQIFERFYRVEKSR
                     STNTGGSGLGLAIAKSIVELHKGTIEVYSDDTKTTFTVKLLPFKG"
     gene            complement(18432..19127)
                     /locus_tag="COE07_RS08360"
                     /old_locus_tag="COE07_08360"
     CDS             complement(18432..19127)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038809.1"
                     /locus_tag="COE07_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_088229145.1"
                     /transl_table=11
                     /translation="MNKNILIIDDDKDIVELLAVYLRNEGYNIYKAYDGEEALQMLCTY
                     EVDLMILDIMMPKRNGLEVCQEVRENNTVPILMLSAKAEDMDKILGLMTGADDYMIKPF
                     NPLELVARVKALLRRSSFQNTATQKKEDGIIRIRTAEIHKHNHTVKVNNEYIKLTSIEF
                     DILYLLASNTGRVFSSEEIFERVWNEDGYGSNKTVMVHISNLRDKLETGMNGEKFIHTV
                     WGVGYKIEK"
     gene            <19357..19485
                     /locus_tag="COE07_RS28240"
                     /old_locus_tag="COE07_08365"
                     /pseudo=""
     CDS             <19357..19485
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108464.1"
                     /locus_tag="COE07_RS28240"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08365"
                     /product="HAD family hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LEKFLERAVFAYISYLWEREDALKVIHLWLKEAYWYFKKIVE"
     gene            19499..20173
                     /locus_tag="COE07_RS08370"
                     /old_locus_tag="COE07_08370"
     CDS             19499..20173
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002156408.1"
                     /locus_tag="COE07_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08370"
                     /product="DUF3885 domain-containing protein"
                     /protein_id="WP_098252120.1"
                     /transl_table=11
                     /translation="MQLKEYMNQTFPGVTLVPYIYSQWENHLHFEFGKGKFPFKEGIDE
                     YNMDYFYQLYKYNNEVFHDIFSKKDTVFLVTNVYRFKKDNIKTPQKMNIYNKYIKKKDL
                     KFRIRQETLSFLFEDDEADLYCTSQFSLKCLAEDIKHEPLIQAANHEDFPELYPRFGRE
                     KRGSYPNIFLINATKDIIMFIYDDRGCEVIAKNKERIRDLYEKYKEWIPGYERESIDNL
                     FK"
     gene            20170..20907
                     /gene="mtnN"
                     /locus_tag="COE07_RS08375"
                     /old_locus_tag="COE07_08375"
     CDS             20170..20907
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /GO_function="GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA]"
                     /GO_function="GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009164 - nucleoside catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /gene="mtnN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129475.1"
                     /locus_tag="COE07_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08375"
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="WP_098840936.1"
                     /transl_table=11
                     /translation="MTVGEVKCVMKRIAIVSAWEPELTYLHQYYPSERVEKRAAWEFHF
                     HTINELEIISVVTGVGKVSCASCVQLLISEFQPDELFMTGICGSLSNKVKNGQIVVALN
                     AIQHDVTAAGSGEDVFNLYNGRTAPIETTKSLVRRIKKIRSYDPIHFGTFLSGDQRIRS
                     SEMRYLLYTVYGALAVDQEVAAFAYVCHINKKPFLCLKAASDQANDKTKEEQKTFKMLA
                     CERACEHLIAFLRVYEITVVNNR"
     gene            20962..21702
                     /locus_tag="COE07_RS08380"
                     /old_locus_tag="COE07_08380"
     CDS             20962..21702
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016362096.1"
                     /locus_tag="COE07_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08380"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_098252122.1"
                     /transl_table=11
                     /translation="MHTYYGELCTKVYESDKSIAGGKELEFYLSFVKDKNMKVLEPMCG
                     NGRMLIPFMQNGIDIVGFDLSVEMLKVCREKAEKFNLKPVISQERIENFHGDKKYDLIM
                     IPIGSFSLLPDNLVDVSLQNMKNNLNENGKFLLTVVLGGNKEEEILDWIETNRKEIKNE
                     LIVEYRKVSNDDVQKLLNIKLKYEIIHDEKIVQTEIMDFPIRLYELKEFENILINNGFS
                     QVVIHEIKDGYGEGNSFHVFECSI"
     gene            21730..22578
                     /locus_tag="COE07_RS08385"
                     /old_locus_tag="COE07_08385"
     CDS             21730..22578
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617036.1"
                     /locus_tag="COE07_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_08385"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_098840937.1"
                     /transl_table=11
                     /translation="MIQYKRCSEVSIDLVYEAFKDGFSDYIIKMDVSKEDFIKRFLGPE
                     GNALEHSFLALDGDKSVGVILGGIKDYESIKTMRCGTLAVHPEYRGIGVSQKLFELHKE
                     EAIQNGCKQLFLEVIVGNDRAVKFYKKLGYEKVYDLSYYNLNDVTKLTNKDNKNVEVKK
                     FEFQTFKLEIQKWLNFHINWQNDIDYIEKTNNSYYGAYVDNDLKGTVCINEHGKISFIF
                     VEKEYRNIGVGTKLLRASSEELKLSSLSIGFPNNGLLEGFLKKSGFKKNALTQYEMYHL
                     L"
     gene            complement(22629..>22991)
                     /locus_tag="COE07_RS28245"
                     /pseudo=""
     CDS             complement(22629..>22991)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612077.1"
                     /locus_tag="COE07_RS28245"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YSLVSRMLEKAFQQLPEEANLLIHSDQGW"
     gene            complement(23151..23285)
                     /locus_tag="COE07_RS28250"
     CDS             complement(23151..23285)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="COE07_RS28250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255291286.1"
                     /transl_table=11
                     /translation="MTKFTSDNKMNAVIRYQDGSESIKDIAKSLRANHEVVRMWIEQF"
     misc_feature    complement(23308..23321)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.94"
                     /tool="antismash"
     misc_feature    23309..23322
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
ORIGIN
        1 agaaataaaa aaatctccta tattgagatt gtaccgaagc aaaaaggtcg gttctttgag
       61 gtgcattata catatgaaat gcacgtttct caaatgaaga aaccatccac gactactagt
      121 aacgctttga gttgcgatct aggtgtagat agattagtaa gttgcgcaac gaatacaggt
      181 gatacgttct taattgatgg aaaaaaatta aaatccatta accagtactt caacaaaatg
      241 atacgtaatc tgcaacagaa aaatatggag aatggacttt ctaaacgtgt tgtaacgaat
      301 caaatggctg cactttggca taaacgcgaa agacaaataa acggttacat ttcacaaact
      361 gtaggcctgt tgttcaaaaa agtgaaagcg tgcaacatag atacggttgt cgtagggtat
      421 aacgctggtt ggaaacaaaa atctgatatg ggaaaaaaga ataatcaaaa gtttgttcaa
      481 atcccatttc ataaactggt ggcagcaatt gagaataaat gtgtaaaaga aggtatccga
      541 tttttaaaac aagaagaaag ctatacttca aaggctagtt tcctggataa agatccggtt
      601 ccagtttggt ctaaggatga taggactcag tatcgcttta gtggcaaacg aatcactcgt
      661 ggtctgtacc aaagtaaagc aggaacatgt atccatgctg atattaatgg tgcgctgaat
      721 acattgcaaa aatcaagagt tgtagaatta gatgacaatc ttaaagtgaa aacgccgatt
      781 ctattagaag tgcaaaaacg taaggctgtt gcttcgcgca tagcttagtg ggtgcgtcaa
      841 ccatccatgt gtactcgact tgtcggggct tgtagcacac gccagattca tctgagtggt
      901 ggtttcttct gcaaggaaga attgctcttt ttcgaaaggg tggtgcaagt ggggaaacga
      961 acgttcgttg ccagtaccaa ccaaaaacat acttggggtg ttaccataag gtggcatgaa
     1021 tgctagagcg tcaaacagtc tagtaataga cgaaaagacc tagcattcta actcaagccc
     1081 ccactgaaac gttttatctc agtggagata gttgacatga agaacaaaat acagcaatga
     1141 tagttagtcg aggattagga aatagtatta ttccgcaaag aatctttaat aggccggaac
     1201 ttatagtcgt acagttaaat taaactgtac gactttttat gtgaaaaagg aaaaggtgct
     1261 tttatatttt atacaagttt acattacaat tttgttaaaa attttctacg ttacataaag
     1321 taacaaaatt tgacctgaag agtttgttat agtgtaaata atcaaaaaac ttaaaaatta
     1381 gtcgagtgaa aagtgtgata aggaattcat gtaaaaaaac ttaaaggggt gtacacatgc
     1441 acaaagaata tgaaattgaa gagtatacgg cgattgagga acaaattcat tattattgta
     1501 aatgtttatt agtaagtcat cctgatcaaa ttataaagta cttagaaaaa agattggaaa
     1561 aatatgcaga aacattacag tatgcacatt tatatcccga cacgattatt ttaccgttac
     1621 agcaattagt tattgaatat tctttagacg ttgctagaat taggaagtat atgaatttaa
     1681 aaacataaaa tgaaatgtat agtgtaaatg aaacagagtc gactttaaga aataatattc
     1741 taatgtcgac tctgtttcat tgtttaatat ttttgattga aaataaatac taatcaatga
     1801 agtttgacat ataattacgc aagagtaaaa taaaagtgag tactcactca ttttgtgaaa
     1861 agggggataa tacatggaac agccttcaat tattttacgg actgtatcaa aaagttttgg
     1921 aaaaaaagaa gttttacaca atctttcatt acaagttgaa aaagcagaga tatttggttt
     1981 agttggtcct tcaggatctg gaaaaacaac acttattaaa atgattgcag gtataaatga
     2041 ggcaacgaaa ggtgaagtac ttgtttgcag cactagtatg cctaacttaa atgaaatgaa
     2101 aagaatcggt tatatggctc aggctgatgc gttatatgaa gaactgtcag catatgaaaa
     2161 tgcagatttt attgcaacaa tgtatggttt aaaaggtaag cgtaagaaag agcgaattaa
     2221 tgaggttttt gaacttgtac aattatccga gcatatgaaa aagccagtac agcaattttc
     2281 aggtggaatg aaaaaacgtt tatcattggc gatagcactt cttcatgaac cagaaatatt
     2341 aattttagat gagccaacag tggggataga tccacttctt agaaaaacga tttgggaaaa
     2401 gttttatgat cttaagaaga aaggtacaac aattattgtg acgacgcaca ttatggatga
     2461 agctgaattt tgtgaacgac tagggttgat tagagaaggg aacttagttg cggttggaac
     2521 acctgaagaa ttgaaaaaac gtgtatcatc aggacgaatt gaggatgtct ttttattaga
     2581 agaggtggtc gaatcatgag agtcaatggt gtaattatcc gtattattcg tcaatttttt
     2641 cgtgataagc gttcgttagc tatgatgttt ggggcaccga tgttattact ttggttatta
     2701 tctctcgtgt ttacacaaaa agattatata ccacatatcg ctgtagtgga tgtaccagct
     2761 ccaatagtga aagcaatgaa aaatcaagac gcatcaattt atgaatatga aaaagaaaag
     2821 gcatattctg aattagaaaa gcaaaaagtg gatgcagtga tacacttaga aaatggaaaa
     2881 atgaaactat tattagaagg cagtgattca tccaaaaatc gtgctgtact tcaagtattg
     2941 caaaagagta cagaaaagaa tgatgtatcg attatgaaac ctgaagtgga gtatttacac
     3001 ggttctaaag actttacgat gtttgatggg cttgggccag tattaatcgg tttctttaca
     3061 tttttctttg tattcatatt gtcaggagta tctttcgtga gagaacgttt aagtggcact
     3121 ttagaaaggt tattgtctac tccggtaaga agatgggaaa tagttgcagg atatattatt
     3181 ggttttggaa tctttgcatt tatacaatct attattatcg taagtttctc tgtctatatt
     3241 ttagacttgt atgtagctgg ctctatatgg ctaacgctcc ttattacatg tatgttatca
     3301 ctaactgcac taacattagg aacgttttta tcggcatacg caaataatga attccaaatg
     3361 attcaattta tcccacttgt tatcgtaccg caagtgttct tttctggatt gtttccaatt
     3421 gaatctatga acaaatggct acaaatgtta ggaaaactat ttccactcac atatggtgct
     3481 gacgcgatga gacaagtgat gattcgaaat caaggattta atgaaattgc actagatctt
     3541 actgttttac ttcttttttc actattattt gcagtaggaa atgtatttgc tttaaagaaa
     3601 catcgcaaaa tataatgatg acaaaaagga gctatataaa tggagaaaga ttggcttgaa
     3661 gaattagttg ctgcaacgaa tacagataaa cgaaatgaac gtcaaatgcg tattttagaa
     3721 gcagccgtgg atatgtttgg agaaaaagga tatgcttcga cttcaacaag cgaaattgca
     3781 aagcgtgctg gtgtagcgga aggaacgatc ttccgctact ataaaacgaa aaaagattta
     3841 ttgctagcag tcgtcatgcc aactttaaca aagtttgcag cgccattttt cgtacaagcc
     3901 tttgcaaaag aaatatttaa atcggagtat gaatcgtatg aaggactttt aaaagttgta
     3961 attcataatc gatttgaatt tgcgaaaaag cattttccaa tgataaaaat actaattcaa
     4021 gaagtaccat ttcagccaga gttaaaagct gaaatacaac aattaataga aacagaactc
     4081 ttttcacatt ttaaaaagtt aattgtaaag tttcaagaaa aaggcgaaat tattgagatg
     4141 ccaccatctt ccgtattacg ccttacttta tcagcggtat taggattact cttaaccaga
     4201 tttttattat tgcctgagga aaaatgggaa gataaagtgg aaattgaaaa tacaattcaa
     4261 tttatattgt acggattaac gccgcggagg taatgtgatg cgccaatttg ctaaaccgaa
     4321 aattgttgta agtaaatgtc tagaatttga tgcgtgtcgt tataatgtag agatgattcc
     4381 agatgtaaca atacgaaatt tacagccatt tgttacattt atcccagttt gtccagaagt
     4441 agaaattggt ttaggaattc ctcgagaaac gatacgaatg gtagaagaaa atggaataaa
     4501 aaggcttgtg caaccgtcga cacgggaaga tgtaactgga aaaatggagc aattttcaaa
     4561 ggatttttta caaacgatat ccgatgtgga tggttttatt ttaaagaatc gctcgccaag
     4621 ttgtggtacg cgtgatgtga aaatttatgc tggttttgaa aaagcaccag taaaaggaaa
     4681 gggagcgggc ttatttggcg gagcagtaat aaaaaaattt tcacatcttc caattgaaga
     4741 agaaggtaga ttgtcgaatt ttattattag agaacatttc tttacaaggt tatttacaat
     4801 cgcatattac aagatgatta aacgtaataa aaatatgaaa gacctcgtat cgtttcagtc
     4861 ggacaataaa tatttattta tggcttataa tcaggtaaaa caaaaggaat tagggcgtat
     4921 tattgcaaat cacaaaaatg aaaagcttga agcggtattt gataagtatg agaagagttt
     4981 atatgaattg tttatgcgca caccccgcta tacatcgaat gtaaatgtat gtgagcatat
     5041 ttttggatat tttaaaacga agttgaaaaa acaagaaaaa gatcattttt tcgatttgat
     5101 acaaaagtat atagaaaaga aagtcccact tagtagctta cttgcaattt taaaatcatg
     5161 ggcccttcga tttgatgaaa agtatttatt aaggcaaaca tatttcgaac cttatccaga
     5221 agctttagta gagatttcag attcggggaa aggtagagat tattaaacaa aaaattgcat
     5281 aattcgacaa gaaaactcct atgttgttgt agaacaatgt aggaattttt ttgtgcatta
     5341 gtacagaatc tgttttaaaa ttaagttatg acagaattat aacaattatc taactaatgt
     5401 tcttgtcttt taagtagcaa tgtttgtagt agaaactcgc acgctgtcga aactcaatat
     5461 tcgataaggg gtgtgtagcg gaatggaatt tactctaact cgcgaaaaac aaatgattaa
     5521 agaaatggta cgtgactttg ctgaaaagga aatcgcaccg aaagctgtgt attatgacaa
     5581 aactgcagag tttccatatg aaacatttca aaaaatgggc gaactaggat tattaggcat
     5641 cccattccca gaagagtatg gaggttcagg tggcgataca gtatcgtacg cgttagcagt
     5701 tgaagaaatt gggcgcgctt gtggtggtac aggcttaagc tatgctgcaa caatttcatt
     5761 aggtgcttct ccaatttatt atttcggtac agaagaacaa aaacaaaagt atttagttcc
     5821 aatggcgtca ggtaaaacat taggtgcttt cggattaacg gagccaaatg cagggtctga
     5881 tgcagggggc acacaaacga aagcggtttt agatggcgat gaatatgtaa ttagtggtga
     5941 aaagtgttgg attacaaatg cagagtatgc aaatacgatt attgtaaccg ctgtcaacgg
     6001 tgttgaagat aatggcagaa aacgcatttc ggcatttatc gtaccaacta ctagtgaagg
     6061 attaacgatt tctagtcctt acgataagat gggtgttcgt gcttctaata cttgtgaaat
     6121 catacttgat ggtgttcgtg taccgaaaga aaacattctt ggtgatgtaa ataaaggatt
     6181 taaacaattc ttatatacac ttgatggagg acgtatttca attgctgcat tagctgttgg
     6241 tattgcacaa tctgcatttg aacgtgcatt gcaatatgcg aaagaacgtc agcaatttgg
     6301 aaagtccatc tctaatttcc aagcgattca atttaaatta gctgatatgg cgactgaagt
     6361 agagctagcg cgtaatttag tacataaagc agcttggtta aaagataatg ataaaccttt
     6421 cggtaaagaa gcggcaatgg caaaactatt tgcatctgaa gcagctagtc gtattgcgaa
     6481 tcaagcagta caaattcatg gtgggtatgg ctatatgcgt gaatatgaag tggaacgaca
     6541 tattcgtgat gcaaaactat tagaaattgg tgaaggaact tctgaaattc aacgtctcgt
     6601 aattgcaaga catttaggat gtagataaaa gggaggaatc actatgtttc aaaaaatatt
     6661 aattgcgaat cgcggggaaa tcgctgttcg tattatgaaa acttgtcaaa aacttggcat
     6721 tcgtactgtt gctatttatt ctgaggcgga tgaaaatgct cttcatgtga aaatggcaaa
     6781 tgaagcttac ttagtaggtg gaccgcgtgt acaagaaagc tatttaaacc ttgaaaaaat
     6841 tatagaaata gctaagaaga caaatgctga agcaatccat ccggggtacg gattattatc
     6901 agagaatcca tcttttccgg ttcgctgtaa agaagagggc atcgtattta tcggtccttc
     6961 agaagaaatc attacgaaga tgggaagtaa aattgagtca cgtttagcaa tgcaagcagc
     7021 agatgtacca gtagttccag ggattactac aaatattgaa actgctgaag aagcaattga
     7081 aattgcaaaa caaattggtt atccattaat gcttaaggca tccgcaggcg gcggaggcat
     7141 tggaatgcag ttgatggaaa ctgagcaaac gctcaccaaa gcgtttgaaa gtaataaaac
     7201 aagggcacaa aacttctttg gtaacggaga aatgtattta gagcgctata tagcagatgc
     7261 acaccatatt gaaattcaac ttttagcaga tacacatggc aacacagtgt atttatggga
     7321 gcgtgaatgt tctgtgcagc gccgaaatca aaaagtaatt gaagaagcgc cttcgccatt
     7381 tttagatgaa ggtacacgaa aagcgatggg agaaattgct gtacaagctg ctaaagcact
     7441 tggttattca aatgcaggta cagttgaatt tcttgtagat gatcaaaaga acttctattt
     7501 cttagaaatg aatacgagat tacaagtaga acatccagtt acggaagaaa ttactggatt
     7561 agaccttgta gaacaacagc tccttattgc aagtggtgaa aaattatcat ttacacagga
     7621 tgatgtaaag cgtatgggtc atgccattga agctcgtatt tatgcagaag atccaaaaac
     7681 attcttccca tcacctggga aaattacaga tttaacatta ccgtcaaatg tacgtatcga
     7741 tcacttctta gagaatcatg taacaattac acctttctat gatccaatga ttgcaaaggt
     7801 tattgctcat ggtgagaccc gtgaagaagc gatttcgaaa ttacatgagg ctttagaaga
     7861 attaaaagta gaaggtatta aaacgaacac gccaatgcta ttacaagtat tagaagacga
     7921 agtgttcaaa gatggcattt atacaacagg ttttgtaacg aaacaacttg ttaaaaaata
     7981 agatttaaca atactaaggg ggaaaaaatg atgacgaaag tatatgcatc gatggcagga
     8041 aacgtttgga agattgttgt aggagtagga gatacagtag aggaagaaca ggatgtcgtc
     8101 attttggaat ctatgaaaat ggaaattcca atcgtttcag aagaagccgg aactgtaatg
     8161 aaaattaacg tgcaagaagg cgactttgta aatgaagggg atgtattagt agaaattgaa
     8221 tagggagata tagggggaag cgaattgaaa ctacctaatt ttgctgtcat taaagaagtg
     8281 ggaccacgtg atggtttaca gaatgaaaaa aagattgttg gcacaaaaga taaagtaaaa
     8341 tggattcaac tacttacaga ggctggatta tcgtacgttg aagtttcctc attcgttcac
     8401 ccaaagtggg tccctgcatt agcagatgca aatgatgtat tttctgagct gaaaagggat
     8461 ccgaatgtta catatgcagc gcttgttcca aatcaaaatg gtttggaacg agcttttttg
     8521 caaaatgtag atgaggtgaa tgttttttta tcagcaagtg aatctcataa taaaagtaat
     8581 attaataaat caattaaaga agcattagtt gtaattgaag atataacaaa acaagcatta
     8641 ttcgaaggga aaaaagtaag aggttatgtt tctactgtat ttggatgtcc ttatgaaggg
     8701 gatataagta ccgcagcagt tgacgaatta tgtaatcagc tattttctta cggcatttat
     8761 gaagtctcgc ttggtgacac gattggtgta gcgaacccgc tacaagtaga gcgagtatta
     8821 gagcatttat taaagaaata cgatgcttcg cagtttgcaa tgcattttca taatacgtac
     8881 ggtatggctc tagcgaatgt agttaagtcg ttagaatatg gtattacaac gtttgatagt
     8941 tcttgtggtg gacttggagg atgtccttat gcaccgggag catcgggtaa tgttgctact
     9001 gatgacctag tacatatgct ccataagtta ggggtccaaa caaatataga tgaagaaaag
     9061 ttattgagag ctagccaatt tattcaaagt aaattaaata tccaattacc gagtcatgtg
     9121 tatagagcgc tgcaacataa aacgataagt aggtgagaag atgctacaat tacaaaacat
     9181 ttcagttgat tatgtaacac ctcacgttgt gaaggtttcg ttaaatcgtg aaagacaagc
     9241 aaactcatta tctttagcgt tattagaaga attacaaact atattaactc aaattagcga
     9301 ggagtcaaat acacgtgtag ttattttaac aggagctggc gaaaaagcgt tttgtgctgg
     9361 tgcagattta aaagagcgtg ccactatgaa tgaagaacaa gttagacatg ctgttagtat
     9421 gattcgttct actatggaaa tggttgaaca attaccacaa ccagtaattg cggctataaa
     9481 cggagttgct cttggtgggg gtacagagtt aagtttagct tgtgatttca gaattgcgtc
     9541 tgacaatgca agtcttggtc ttactgaaac tacgcttgct ataatacctg gagcaggtgg
     9601 tacgcagcgc ttaccgagat taatcggcgt aggtagagcg aaagaactaa tttatacagg
     9661 aagacgtatt tcatctcaag aagcgaaaga atatggttta gtagaatacg ttgtaccggc
     9721 tgaaagatta gaagaaaaag caattgaaat tgcagagaaa attgctagta atggaccaat
     9781 tgctgttcga ctagcaaaag aagcaatttc aaatggtatt caagtagatt tacataccgg
     9841 attacaaatg gaaaaacaag cgtatgaggg cgtaatccac acgaaagata gagtagaagg
     9901 attacaggca ttcaaggaaa aacgccaacc aatgtataag ggggagtaaa tatgttagat
     9961 caaaaacagc aaactaattc atttgaagaa cgagttgaaa caattaagca aggcggagca
    10021 ccgaaatatc atgaacaaaa caaagcgaaa ggtaaactat ttgttcgtga tcgtttagct
    10081 cttctgtttg ataacggtga atatgttgaa gatgcattat ttgcaaattg tgaacaaaat
    10141 ggattaccag ctgacggcgt tgtaactgca accggtaaaa tacacggtcg tactgcgtgt
    10201 gtaatggcaa acgattcaac ggtaaaggct ggctcatggg gatcacgtac agttgaaaag
    10261 attttacgta ttcaagaaac ggcagaaaaa ttacgcgtac cattatttta tttagttgac
    10321 tctgctggtg cacgtattac agatcaagta gaaatgttcc cggggcgccg cggtgcggga
    10381 agaatctttt ataatcaagt aaaattatca ggtaaagttc cgcaaatctg cttattattt
    10441 ggaccttcag cagctggtgg tgcgtatatt ccagcatttt gtgatgttgt tatgatggtg
    10501 gaaggaaatg catctatgta cttaggctct ccacgtatgg ctgagatggt tatcggcgag
    10561 aaggtaacgt tagaagagat gggcggagct cgtatgcatt gctctgtatc aggatgcgga
    10621 gatgtattat gtaagacaga agaagatgca attacgcaag ctagacaata tatttcatat
    10681 tttccaagca actacttaga aaagactcca ttgatttcac ctcaagaacc gaaacagttc
    10741 gataaaacgt tagaacaaat cattccagaa aatcaaaatg ctcctttcaa tatgaaagat
    10801 ctcattaaca gagttattga tgaaggttct ttctttgaag tgaaaaaatt atttgctcaa
    10861 gaattaatta caggtttagc acgcattgat ggtaaaccaa tcggtattat tgcaaatcag
    10921 ccgcgtatga agggtggcgt attattccac gattctgctg ataaagcggc taaatttatt
    10981 aatttatgcg atgcatatca tattccatta ttattccttg cagatgtacc aggatttatg
    11041 attggtacga aagtagagcg tgctggtatt attcgtcacg gtgcaaaaat gatttctgca
    11101 atgagtgaag caacagtacc aaaaatttct attatcgtcc gaaaagcgta tggggctggt
    11161 ttatacgcaa tggcaggtcc agcattcgaa ccagattgct gcttagcatt accgacagct
    11221 tctattgcgg taatgggccc agaagcggcg gttaatgcag tatatgcaaa taaaattgca
    11281 gctttaccag aagaagagcg cgcaagcttc attgctgaaa aacgtgaaga gtataagaaa
    11341 gatattgata tttaccactt agcatcagag atggtgattg atggtattgt tcatccgaac
    11401 aatttacgtg aagaattaaa aggacgattc gaaatgtata tgagtaaata tcaagtattc
    11461 acggatcgta aacatcctgt atatccagtt taaaagccct atttagggct ttcttgctca
    11521 aaaagtcaag gaggggaaaa cattgaaaca agcagtttgg tttccaacag aagagtataa
    11581 ggaaaaaacg cgtttattta gttggatgaa atcattaggc tatgaagatt atgaagcttt
    11641 ttataataaa tcaatttcag aaacagcgtg gttttgggga gaagctgaga aagcagttgg
    11701 ctatcaatgg atggaacgat atacggaagt gttagattta gaaaatggta caccgtttgc
    11761 acagtggtat actggcggaa catgtaacgt tgtagagtct gttttatctc ggtggattgc
    11821 tgacgatgaa atgaaaagac aacctgcact tatgtacgaa ggagaaaatg ggacttcgaa
    11881 atcatataca tatgaagagc ttgacagctg ggtaagccgt gttgcaaacg gtttgaaaca
    11941 agctggtatt gagaaaggcg atcgtgtaac aatttacatg ccgatgattc ctgaaacagt
    12001 tgttgctatg ttagcagtaa tgaaaattgg agcgattatt tcaccaatat tctcaggttt
    12061 tgcagctgat gcagtaatga cacgtgtaca agcagctggt tcaaaaatga taattacggc
    12121 agatggtttt tcgcgccgag gtaaaattgt ttcattaaaa gatgaagtag ataaagcttg
    12181 tgaacattgt ccaactgttg aaaaagttgt aatcgttcgg cattcgggaa atgattttac
    12241 tccgcataac tatgatttct catggagtac attagaaaaa gaaaaaccat ttgtacatgc
    12301 tgaagaaatg aatagcgacg atccattgat gctcatttat acatcaggaa cgactggtaa
    12361 accgaaagga acagtgcata cgcatgctgg ttttccgcta aagtctgcat ttgatgcagg
    12421 atttggaatg aatataaaac aaggtgatcg tgtattatgg gtaactgata tgggctggat
    12481 gatgggacca tttttactat tcggctcttt aattaatgga gcaacgatgg ttatgtacga
    12541 aggtgtgcca gacttcccag aagcagaccg cttatgggag acggttgata aatatgaaat
    12601 cacacatctc ggtatttcac caacattaat tcgtgcgtta atggcaaaag gtgatgagta
    12661 tgtaaataaa cactcgctca agagtttaga agtattcgca tcaacagggg aaccttggaa
    12721 tccggatccg tggatgtggc tgtttgaaac ggttggaaaa ggaaaagtcc caatctgtaa
    12781 ctattcagga ggaactgaaa tttctggagg gatttttggc aatgtgctta ttaagccaat
    12841 tgcaccaatt agttttaacg catccttacc aggaatggca gcggttgtac ttgatgatca
    12901 aggtaaacca attcgtgatg aagtcggaga actatgttta gagaaacctt gggttggaat
    12961 gacaaagagt ttctgggaag acgatgagcg ttatgtaaac acatactggt cacgttttga
    13021 aaataagtgg gttcatggtg attgggttgt ttatgacggt gagcaatata ttattacagg
    13081 acgttcagat gatacgttaa atattgcagg taaacgtatt ggccctgctg aatacgaatc
    13141 tattctcgtg aaacataatg atgtaataga agctgctgca attggtgtac ctgacgatgt
    13201 aaaaggtgag gtttgccatt gttttgtagt attaagagac ggtgtaacat tcactggaga
    13261 gttaaagaaa gaattaatga gtttagtaaa ctctcatatt ggaaaagcat tatgtcctaa
    13321 agatattcac gttgtagaag acttaccgaa aacacgtaat tcgaaagtaa tgcgtcgtgt
    13381 tattaaagca gcttacttag gaaaagagtt aggagattta tcgtcacttg ttaaccctga
    13441 agtagttccg tttattcagg ggttgcagtc tagtaaatta taaaactagg tatgagctct
    13501 atttaattag agctcatttt ttgtattaaa aaatatgagg ccaaacaagg agaaaatatt
    13561 gaaatagaag gtggaaatta aactataatg tttctcactt taatctaaat ataggtattt
    13621 tgtatttgaa aatagaaagt gcattttgct tttcttaaaa aattctagtg tgaattaagt
    13681 ttgagttatg ttcgttgtaa tacaacttgc taaaaattta tcattaaatg taagtgcacc
    13741 ttcaatagta aatggcatta caattgttag attcttactc acataatcaa atccaacttc
    13801 ttgttcgcat tcgccgcaac taacagaaga agatataagt gtgccagata aaatattata
    13861 gacaatggtt aaacaaacag gccgagttaa tcctggtaag acacagggca aagtgtttcg
    13921 acctcctttt ctattaatag gaaatgtaac ggattcgctt ttgggaaagg aagaagagat
    13981 taaataataa atttaaaatg aaaataaaac gtaggttttg tttgttgatt ttgaagggag
    14041 agaggggaat tagaagttat aattctattt tcccctaaca aattacttag attaaggttg
    14101 tgttaaattc gttgtaacgc aacttgcctg gaatttgtca ttgaatataa gagtaccttc
    14161 accagtaaat ggtactctta taactagatt cttactagta taatcgaatt cagttgatag
    14221 agcacaactt ccacaatcaa cagtagaaga tattagtata cccgatgaaa cattataaac
    14281 aagtgttaaa caaagtggct gtgttaaacc tgtaacaata caagacattc tatttacacc
    14341 tcctattctc ttacttatta atagaaaatg caaatgggat aacttttgaa acggtatata
    14401 cggaaataaa taaaatatcc catctggttt aacagaatga aaattacaaa gtagatttaa
    14461 atagcaaatt gatagacctt actaaaatat agctttaaat aataatttta aacgaacaaa
    14521 ctggcattta attgttggag ccagttttat attttttcta gaattaaaat tattaaaggg
    14581 aaaaactatt gatgtgatta cggttatctc aagtatttaa atgcaaggtt gaaacggtaa
    14641 tgaatgtact ttgaaactaa taaaaagatt tagtacaaaa gtttgttttt tcttttctat
    14701 gttcttgcct cgtacatttt taagctagtg gacatacttt actattagga agaattaggg
    14761 ggtgagattt tgggttatcg ttatagtaat tctaaaaaga agtgtacatg taaacaggat
    14821 gattgttggg atgcttttga agagtgtaaa aaagaacaag aagaacaaaa taaaaaatgc
    14881 gactgttgct gtgtgcaagg aattagagat gagcttaaaa aattagtaaa tagagcagtg
    14941 cgcattaata caggaagtaa taattatgca gggactgttt cttcagtcac ttgtgatgtt
    15001 gtaaagcttg ctaatagtgc tggggtagtt acagtcatta tatcagtttg taaaattgaa
    15061 gcgattgagc cattgttgac ataggaaata tggtgtaatt aggctatgtt tttataaagc
    15121 cattcttatg aatggcttta ttttcatttc gtataaaagg agaatatatt ctatacatag
    15181 aaataagctt gaggatatat agaatggtgc atgaaaggag aatggagttg attaaactag
    15241 aaccctttaa aagagtcgat ttcaaacaat taataaattg gatccattcc gaagaatttt
    15301 taatacaatg gtcgggtaat gcatttattt atccattaga tgaacagcaa ttacataaat
    15361 atatcgaaag tataaacaca ctagctttca aagtaataga tgaagagact ttaaacgtta
    15421 ttggccatat ttcgcttgga caaatcgaca atataaataa gtctgcgagg attggaaaag
    15481 tgttggtagg tgatacgaaa atgagaggac gttctatagg aaaacatatg atgaaagcaa
    15541 tactttatat tgcttttgaa gaattgaaac tacatagagt tactcttggt gtttatgatt
    15601 ttaatacgtc agctatttta tgttatgaaa aaatagggtt tgtaaaagaa ggtttattaa
    15661 gagagtcaaa aaaagtagga gatacgtatt ggaatttatg ggaaatgagt atgttggaat
    15721 atgaatggga caataaaaaa taatagttct atataattgt attatgttaa ctaaatgacg
    15781 agtgggaaat tttcatattg tagatattgc gtatagctgg atttgtgatt tgaaaggaag
    15841 tagatgagct gcaatttagg ggttatcaat caattcaaag tttcatggac gaataaagag
    15901 tataggtatg gtgaagtatt acgacacgtt attgtacatg aaattcatca tataggtcag
    15961 ctatcaatat gggcaaaaga gttaaacctt cagcctgttt cagcgaattt aattggaaga
    16021 gggtatagat cttaaaaccg acttacactg caaacgcaag tcggttttat atataagaag
    16081 attattcagt tgaaatcctc ggattttttt tgacgtatat gtaaaaacat taatattgta
    16141 atgatgaaaa aaattatcat cgtttgtata attaaatttt taaattgaag taatattgac
    16201 caagatgtaa gagcatcttt aaaagcttga agtgcggagt aggaggaagg atcaaaaccg
    16261 tactgtagta atttttttgt ttcgataaaa gtactgtttt cttcatcggc ttctaatact
    16321 actgaaatta gccttgtgtc acctcgctta gctgtaccga caaaactata attaccgtta
    16381 gttgaaaaac tagtttgcaa gccatcaaca ccttggagtt taatgttttt attaagggaa
    16441 taaatcatct tattcgtgtt aaaaacttgg aaatctttga aggtaaattg gtaagaggtt
    16501 agtttcgtaa tgttcagcac atctggaaaa tcttttacta attgtgttgc tagtttagct
    16561 gcgtctatcg ctgttgtact aggttgttca tttgtatctt gattaacacc agtagagttt
    16621 agaaatggag atgattgtga caactgtaat tgttttgctt tttcattcat taacgttgta
    16681 aagctatctt catttccacc aatgtgttct gctagcgcaa gtgcggaacg attatttcct
    16741 gttagaagca atacataaag taaatcgcga accgtcgttt tatcctttga cgttatttga
    16801 ataggacttg tttccacttg gaacacttcg ttacttattt ttacagtttc atccaactgt
    16861 atttttccgt tatttagttg ttctaacacg atatactctg tcattaattt agataaagta
    16921 gtggattgta ttagagtttc ttcatttttt ttataaataa cttcacctga attagcatct
    16981 attaaaatag ctgatttagc ttgaataact ggaccattta cataaagata aaaatataaa
    17041 acgataagtg cagtaatgag aaaagataat aataaaactg ttattttttt taagaattgc
    17101 ataagcgatc ctcctactat gacatcaata ttattattgt aagaaggaat gcttaattag
    17161 gaagaaagaa aaggtaaaga atttctaaag atttataaag gattatttaa ttttggatat
    17221 ttatagaaaa acaaaaggtt caatttctta tcgtagaaga aattgaacct gaatttaggt
    17281 tagattaacc tttaaaaggt agtagtttta cagtgaaagt tgttttagtg tcatcactat
    17341 atacttcaat tgttccttta tgcagttcga caatactttt ggcaattgct aatccgaggc
    17401 cagatccacc agtgtttgtt gagcgtgatt tctcaacgcg ataaaatcgt tcgaaaatct
    17461 gaggtaaatc tgtactagga atgggttgcc cgtaatttgt tatatcaatt gtaatcatat
    17521 tattgctttc ataagcagta aggtcaatat agccgccatc gtttccgtac gtgatagcat
    17581 ttataataag attttcaaat acgcgtacta atttgtcacc atcagctaat accatgagtt
    17641 tttgagatgg gaaggaaggc ctgcattcta tgttagcttc ttgaacctgt attcggaatt
    17701 gaacagttaa ttggccaagt agctctacaa tatcaatggg agcagaatat aaacttaact
    17761 ctttattttg aacacgtgta tattcaaaca aatcattcat taatgcatta aggcgtgtta
    17821 ccttatcata aatgacctgt atataatgac gcaattctac ttcatctcta taattatcat
    17881 gctggattaa atttacgtag cctactattg atgtaagagg ggttcgcaag tcgtgtgata
    17941 catttgtaat gagttcgctt tttgcttgtt ccgcttgtct ttcttcatca attgagactt
    18001 ttaattgttc aacaatttga ttgaccccag ttgctaattc ttctaaataa ttatgattta
    18061 cgatggaaac tttgtgattg aaatttccac ttgcgatata gcgaatctct tcgatcattt
    18121 tttttataca agtttcatag tacatctttc tttcatgacg ataaaaaata tataaatagg
    18181 atgagaaaat agagaataga aacaaataag atacaatcat catccagagg gattccttta
    18241 gccctttata tttttcatag ccgaaaattc taatgaattc tttactgagt tcacttaaag
    18301 taagggaact ctcaattaca ctcgttatga ggcgatatat aattaattcg gtaataggag
    18361 ttagtgtgat agctaataag agccaaaaaa taattttcca ttttggaata tcttttaata
    18421 tatcaaatgc ttcatttctc aattttatag cccactcccc aaacagtatg aataaatttt
    18481 tctccattca ttcctgtttc aagtttatca cgtaaattac taatatggac cataacagtt
    18541 ttgttagaac cataaccatc ttcattccat acgcgttcaa atatttcttc tgagctaaat
    18601 actcttcctg tattgcttgc aagtaagtat aaaatatcaa attcaataga tgtaagctta
    18661 atatactcat tatttacttt cacggtatga ttatgcttat ggatttcagc agttcgaatg
    18721 cgaatgatac catcttcttt cttttgagta gcagtgtttt ggaaagaaga tcttcttaac
    18781 aaagctttca ctctagccac tagttctagt gggttgaatg gtttaatcat gtaatcatct
    18841 gcccctgtca tgagccctaa tattttatcc atatcttcag ctttggcact tagcataaga
    18901 ataggcacag tattattttc acgaacttct tggcaaactt ctaatccgtt acgttttggc
    18961 atcataatat ccagaatcat aagatctact tcatatgtac atagcatttg taaagcttcc
    19021 tcaccatcat atgctttata aatattatag ccttcatttc gtaaataaac agcgagtaat
    19081 tccacaatat ctttatcatc atcaataatt aatatgtttt tattcattat ttagttagtt
    19141 cctttcctta caaatcatca acattacaat aatatcaaac atttatgtac tttgtagcaa
    19201 tgattccaca taaaaattta ttttacgtat taaaaaggaa ttaaaacatt tatagcgaat
    19261 acaaaataag agtaatattt aaatttcgta ttataacgaa gaatagttat aaggaggatt
    19321 cgctatgtta taatgatata tattcattta ttccaactag aaaaattttt agaacgtgct
    19381 gtatttgctt atatttcata tttgtgggaa agagaagatg cattgaaagt tatacatctg
    19441 tggctaaaag aagcatattg gtactttaaa aaaattgtag aatagagagg tcatgaaaat
    19501 gcaattaaaa gaatatatga atcaaacatt tccaggtgtt acattagtac cgtacattta
    19561 ctctcagtgg gaaaatcatt tgcattttga gtttgggaaa ggtaaatttc cattcaaaga
    19621 aggaatagat gaatacaata tggattattt ttatcagtta tataagtaca ataatgaagt
    19681 atttcatgac atattctcga aaaaagatac agtgttttta gtaacaaatg tttatagatt
    19741 taaaaaggat aatattaaaa ctccacagaa aatgaatata tacaataaat atattaagaa
    19801 aaaagattta aagtttcgca taagacaaga aacattatca tttctatttg aagatgatga
    19861 agcagattta tattgtacat ctcaattttc tttaaaatgt cttgcggaag atattaaaca
    19921 tgaaccgctt attcaggctg ctaatcatga agactttcca gaactttacc ctcgttttgg
    19981 acgcgaaaaa aggggttctt atccaaatat atttctcata aatgcaacga aagatattat
    20041 catgtttatt tacgatgata gaggatgtga agtaattgcg aagaataaag aaagaatacg
    20101 agatttatat gagaaataca aagagtggat tccaggttat gaacgagaaa gtatagataa
    20161 cttatttaaa tgacagtagg ggaagtgaag tgtgtaatga aacgtattgc aatcgtatcc
    20221 gcatgggaac cagaacttac gtatttgcat caatattatc caagtgagcg cgttgaaaaa
    20281 agagcagctt gggaatttca ttttcatact attaatgagc tggaaataat atcagttgta
    20341 actggtgttg gcaaagtaag ctgtgctagt tgtgtacaat tattaattag cgagtttcag
    20401 ccagatgagt tatttatgac aggcatatgt ggaagtctat caaataaggt aaaaaatggt
    20461 caaattgtag tagctcttaa tgcaatacaa cacgacgtta ctgctgctgg ttcgggagaa
    20521 gatgttttta atttatataa tggtagaaca gcacctattg aaacaacaaa atcacttgta
    20581 agaagaataa aaaaaatacg gtcttatgat ccgattcatt tcggtacatt cttatctggg
    20641 gatcaacgta ttcgcagttc agaaatgaga tatttactct atactgtata cggagctttg
    20701 gcggttgatc aagaagtggc agctttcgct tatgtttgtc acataaataa aaaaccattt
    20761 ttatgtttaa aagctgcttc ggatcaagca aatgataaga cgaaagaaga acaaaaaacc
    20821 tttaaaatgt tagcatgtga aagagcatgt gaacatttaa ttgctttttt acgtgtttat
    20881 gaaattactg tagtaaataa tagatagcag aacttatata acaaaccatc catgtatttt
    20941 aagttgagag gtggaataat attgcatacg tattatggtg aactttgtac aaaagtatat
    21001 gaaagtgata aatcaattgc gggcggaaaa gaattagaat tttatctttc ttttgtaaaa
    21061 gacaaaaata tgaaagtgtt agaaccgatg tgcgggaatg gtagaatgtt aattccgttt
    21121 atgcaaaatg gtattgatat agtagggttc gacctttccg tagaaatgct gaaagtgtgt
    21181 agagaaaaag cggagaaatt taacttgaag ccagttatat cgcaagaaag aatcgaaaat
    21241 ttccatggtg ataaaaaata tgatcttatc atgataccaa ttggatcatt ttcactttta
    21301 cctgataatt tagtagatgt tagtcttcaa aatatgaaaa ataacttaaa cgaaaatggg
    21361 aaattccttc ttaccgttgt attaggaggg aataaagagg aagagattct tgactggatt
    21421 gaaacaaata gaaaagaaat taaaaatgaa ttgattgttg aatatagaaa agtatcaaat
    21481 gatgatgtgc aaaagctttt gaatattaaa ctaaagtatg aaattattca tgatgaaaaa
    21541 atagtacaaa ctgagattat ggattttcct ataagattat atgagttaaa agagtttgaa
    21601 aatatcctta ttaataatgg gtttagtcaa gtggttattc atgaaataaa ggatggatat
    21661 ggtgaaggga attcatttca cgtgttcgaa tgtagtatat aacaagccaa agcggaggat
    21721 tatacttata tgattcaata caaaagatgt agtgaagtaa gtatagattt agtgtacgaa
    21781 gcttttaaag atggattctc agattacatc attaaaatgg atgtttcaaa agaagatttt
    21841 attaaaagat ttttgggacc agaaggaaat gcgctagaac actctttttt ggctttagat
    21901 ggtgataaat ctgttggcgt aatactgggc ggtataaaag attatgaaag tataaaaaca
    21961 atgcgttgcg gaacattagc cgttcatcca gagtatcgag gaattggtgt aagtcaaaag
    22021 ttatttgaac tgcataaaga agaggcaatt caaaatggat gtaaacaact ttttctagag
    22081 gtcattgtag gtaatgacag agcggttaaa ttctataaaa aactaggtta tgaaaaagta
    22141 tatgatcttt cttattataa tttaaatgat gtaactaaac taacaaataa agataataaa
    22201 aatgttgaag tgaaaaaatt tgaatttcaa acatttaaac ttgaaattca aaaatggctt
    22261 aacttccata taaattggca aaatgatatt gattatattg agaaaacaaa taattcgtat
    22321 tatggtgcat atgttgataa tgatttaaaa ggtacagtat gtataaatga acatgggaaa
    22381 attagcttta tatttgtaga aaaagaatat agaaatattg gtgttggaac gaaattatta
    22441 cgagcatcaa gtgaagaatt gaagttatca agtttgtcaa tcgggtttcc taataatgga
    22501 ttactggaag ggtttttaaa gaaaagtgga tttaaaaaga atgcattaac acaatatgaa
    22561 atgtatcatt tattatagaa gcagaaggaa gtatgaactg accccataaa gttagacagg
    22621 tcgtttcatt aggcagcctt tagggcatga gttcgatatt gtagcggact catgcctttt
    22681 agttttgcct taattctttt gtgattataa taatcgatat atttttcaaa ttcttgttta
    22741 aagtgttcta tgctttcaaa atcttttagg taaagaaatt cagagttcat agtaccaaag
    22801 aagctttcaa taaccgcatt atcgtaacag ttccctttac gagacatact ttgcgtaatc
    22861 ttgcgtttct ttaaggcatg acgatacttc ttcatttgat actaccaacc ttgatctgag
    22921 tgaatcagaa gattggcttc ctctggtaat tgttgaaaag ccttctctaa cattcttgag
    22981 acaagtgaat agatgtgcca ttttctaata agtccaggta aagaaatact gaaaataact
    23041 gccgtttcgt ttggagacgt cccattctcg atcatataat ttagtacgtc tagtttatac
    23101 tgtgcagaat acgttgtata gcctttttta aacgcttgaa ttccataata ttaaaattgt
    23161 tcgatccaca tacgtactac ttcatgattc gctctcaatg atttcgcaat atcttttata
    23221 ctttcacttc catcttgata acgtataact gcattcattt tgttatctga agtaaattta
    23281 gtcataaaaa aactacacct ccaattgtta gactgtgtct aacaattgga ggtgtagttc
    23341 aagtagtctt tctgcttttt atttttgtca taaaataatc ccctgtcgta caaacctcat
    23401 atctacagtt ttcaaagaac aatctgtagg acatgattat agtaaatggt tataacaaag
    23461 ccatatattg ttaaaatgcc gta
//
