LOCUS       NZ_NUOG01000008        23508 bp    DNA     linear   CON 31-JUL-2024
DEFINITION  Bacillus sp. AFS033286 AFS033286_82_A2_Contig11_140604, whole genome
            shotgun sequence.
ACCESSION   NZ_NUOG01000008
VERSION     NZ_NUOG01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. AFS033286
  ORGANISM  Bacillus sp. AFS033286
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 236583)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 236583)
  AUTHORS   Bleich,R.M., Grubbs,K.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 78.73x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002583065.1-RS_2024_07_31
            Annotation Date                   :: 07/31/2024 14:02:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,319
            CDSs (total)                      :: 5,247
            Genes (coding)                    :: 4,997
            CDSs (with protein)               :: 4,997
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 250
            CDSs (without protein)            :: 250
            Pseudo Genes (ambiguous residues) :: 0 of 250
            Pseudo Genes (frameshifted)       :: 83 of 250
            Pseudo Genes (incomplete)         :: 197 of 250
            Pseudo Genes (internal stop)      :: 59 of 250
            Pseudo Genes (multiple problems)  :: 74 of 250
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:15:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 115390
            Orig. end                         :: 138898
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NUOG01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23508
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23508
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23508
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13508](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13508)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(459..477)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     gene            506..865
                     /locus_tag="COE07_RS03030"
                     /old_locus_tag="COE07_03030"
     CDS             506..865
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016082428.1"
                     /locus_tag="COE07_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03030"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_088231398.1"
                     /transl_table=11
                     /translation="MLRRKLLYLLLTVPLYAWLISMTKIEVMALFLGYVFIFSNLNRIQ
                     EQSILEVCIFSISIELFSIVSIVLLNELFRWIYSFELIKLGNIVLQVICAYIVFVMLDK
                     IIRQQTVFQDKRNWD"
     gene            981..2480
                     /locus_tag="COE07_RS03035"
                     /old_locus_tag="COE07_03035"
     CDS             981..2480
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002201340.1"
                     /locus_tag="COE07_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03035"
                     /product="L-lactate permease"
                     /protein_id="WP_098252428.1"
                     /transl_table=11
                     /translation="MSVLLALIPIMMIFICLFLFKQTSLRSSLISYAVSVGIVLLSPTF
                     RLGISETVHATIKGSLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTHDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPMFAYFVILSLHVVGGWKAVIEKWKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSEQNLITEHAAATEREVSIIKIISP
                     YIFLTVCILLSRLVPALHDLLKSYAVLDLKSYSYKLEMLYSPGFWLGMTCLFTIIFFRI
                     PSHIIKQSLSQTIKQWIPFAITTTMFIAIAELMGASGMHSLLAKTAGETFGTFFVFVAP
                     FIGGIGGFLTGSNAGSNAMFIKLQMQTAQNVALPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPHRENELLKKTTLMISGAVLLVVVEVVIWYMLRK"
     misc_feature    complement(1010..1025)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            2572..3255
                     /locus_tag="COE07_RS03040"
                     /old_locus_tag="COE07_03040"
     CDS             2572..3255
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128607.1"
                     /locus_tag="COE07_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03040"
                     /product="DUF2278 family protein"
                     /protein_id="WP_088231396.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVIQSKIGKGKTPHYQVHLQGEAGVDYRIAINVK
                     SQSYPSEVLYFASDNIRSEAIHILPTLPFGFTQIKNNEPKVALDYVRGNLFDSKQMIPL
                     PAEKAGVDNDLNEKIERYIKRAIEEKAIIYAFGERWGPEENTPDSYFHFEPGNGIHDIH
                     MNQGNVEKWKGDNGIWQDGGILIHFEKEEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKRSN"
     gene            complement(3552..4385)
                     /locus_tag="COE07_RS03045"
                     /old_locus_tag="COE07_03045"
     CDS             complement(3552..4385)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017762920.1"
                     /locus_tag="COE07_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03045"
                     /product="hypothetical protein"
                     /protein_id="WP_088231395.1"
                     /transl_table=11
                     /translation="MEFVNSIFQILLTSVIQLFSLIGVIIVIGFLLGYLESLTRTYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCILFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     IYQRIGNFFIGIGPIISGITALILLMRYFVPESYSLFNTTLETTVSSTSINLEMVQNMF
                     LSTFVLLKSLFTISNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNLLIGQVMKYNMYLIAFSSVALLFSCISTLVSFVFYKIRGGRSF"
     gene            4582..5364
                     /locus_tag="COE07_RS03050"
                     /old_locus_tag="COE07_03050"
     CDS             4582..5364
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158836.1"
                     /locus_tag="COE07_RS03050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03050"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_088231394.1"
                     /transl_table=11
                     /translation="MKCSACHTENAAEAKFCGNCGHSLTEEVVASGVPEGGHQPSAAQV
                     KETRPNETVEQAKRFASGYFQFFKHALKAPTAIMKSGNIEVRNGITSLLLICFLGACIF
                     YRIMSAGAALTRTLAPDLSTPSFFGESIKVFLFLLILTLFVGFIIFVSGKMMKSSFSFL
                     EVFGIWGTIATPAIAILVLSFLFSFLLILFLPLLLGLATTYMGISIVVAIAKLDNGGLD
                     LVYTLLIANVLNGIVVWIIFWSYFNMIIQTFTGGLTGF"
     gene            5384..6619
                     /locus_tag="COE07_RS03055"
                     /old_locus_tag="COE07_03055"
     CDS             5384..6619
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017672808.1"
                     /locus_tag="COE07_RS03055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03055"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_088231393.1"
                     /transl_table=11
                     /translation="MNVCTKCGIQFEDGVQFCQNCGTKRGNPVVKKNMNGGTKVGITLL
                     ALFIIAIVGLYLYGSSYYAQGAQVDRMITILQERDGEKLAEIITADDPSVVVTRESVMP
                     LFSYIKENPSYVNELKAYLIQGEKQGDGIERADFSLTKDGKYFVIFDRYRLKAKTYYTT
                     LLSNEKGTSLKMNGKEIDKTDDKKFEKQYGPFLPGTQVFQSEYKNEYVKLLREEKVVLM
                     KQSQNNVTIDLTLQGKYITVQTNMPGATLYVNQKPVTALAGEEITWGPIATDGSATIYL
                     ERNGESGRETTKVETVTALSSYNLPFQKKSEEKTVVYNVAPTPTTGYVYNGFIFPDSDI
                     RKLTSSDLRYLSKEQLKIARNEIYARHGHMFQTKDMQAYFSKQSWYRENPYFTGVLTNI
                     ESYNVELIKSRE"
     gene            complement(6657..7085)
                     /locus_tag="COE07_RS03060"
                     /old_locus_tag="COE07_03060"
     CDS             complement(6657..7085)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135033.1"
                     /locus_tag="COE07_RS03060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03060"
                     /product="hypothetical protein"
                     /protein_id="WP_088231392.1"
                     /transl_table=11
                     /translation="MCASLLVQLPEEPIEPRPALPLEQEFSVNATIYSARAWLSNDETF
                     AQTIWKASRFASASHARKSIFPVGTVKIVNFSDDTITVTISSESEDALKIIVPPHSEAA
                     LTSSALSDVQASTSGKASKVTFLFHIFFSRDPGSDKKP"
     gene            7285..8619
                     /locus_tag="COE07_RS03065"
                     /old_locus_tag="COE07_03065"
     CDS             7285..8619
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="COE07_RS03065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03065"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_088231391.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.2e-64, bitscore:
                     209.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDKSANVVTLEKGEIYSYAQCGLP
                     YVISGAIASAEKLIARNVKTFRDKYGIDAKVCHEVTKVDTEKKIVYAEHTKTRDVFEFP
                     YDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERIVKTLETNEIENVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDYVGTIYDADMAEYIHKEADKHHIEILTNENVKAFIGKER
                     VEQIETDKGTYKADLVLVSVGVKPNSDFLEGTGIRTNYKGAIEVNAYMQTNVKDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMVDKRRAFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPSAKPLHLKLLYRTDTKQLLGGQVMGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            <8643..8729
                     /locus_tag="COE07_RS28570"
                     /pseudo=""
     CDS             <8643..8729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="COE07_RS28570"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="GNAT family acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VQREVNIEFD"
     gene            8876..9286
                     /locus_tag="COE07_RS03070"
                     /old_locus_tag="COE07_03070"
     CDS             8876..9286
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="COE07_RS03070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03070"
                     /product="DUF3908 family protein"
                     /protein_id="WP_088231390.1"
                     /transl_table=11
                     /translation="MAINIKTIEEWIAESNARQEEDFGRVVEEMKEVCVGLDNATLIYA
                     KNVFCFGKKVEVLFFFQDHVVIGQETDEYVEIEKLKYDDITNSNLKTNDKNTTLALKFA
                     NGKSIDLDSLNDNYGTKNWLFARQIKSIFKLI"
     gene            complement(9318..9908)
                     /locus_tag="COE07_RS03075"
                     /old_locus_tag="COE07_03075"
     CDS             complement(9318..9908)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (49-149). E-value: 6.7e-11. Score:
                     32.8. Matches aSDomain: nrpspksdomains_COE07_RS03075_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025743.1"
                     /locus_tag="COE07_RS03075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03075"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_088231389.1"
                     /transl_table=11
                     /translation="MSILQRLIQQAKNPRGTIGSSMLCIMNAAHTRLTHWGLQKIHIRK
                     DAITLDIGCGGGKTIHTLSKRIPLGKIYGIDYSNQAVENSKKANIQDVKKGKVIIHQAS
                     VSSIPYNTNFFDLITAFQTHYFWPDVEQDIKEVFRVLQPNGSFLLVAETFKIQYHMENF
                     KTNEELVNLFYKTGFTRVQCYEEKGCLCVIGSK"
     aSDomain        complement(9462..9761)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_COE07_RS03075_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.70E-11"
                     /label="COE07_RS03075_oMT.1"
                     /locus_tag="COE07_RS03075"
                     /protein_end="149"
                     /protein_start="49"
                     /score="32.8"
                     /tool="antismash"
                     /translation="LDIGCGGGKTIHTLSKRIPLGKIYGIDYSNQAVENSKKANIQDVK
                     KGKVIIHQASVSSIPYNTNFFDLITAFQTHYFWPDVEQDIKEVFRVLQPNGSFLL"
     gene            complement(10001..11542)
                     /locus_tag="COE07_RS03080"
                     /old_locus_tag="COE07_03080"
     CDS             complement(10001..11542)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124293.1"
                     /locus_tag="COE07_RS03080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03080"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_098252426.1"
                     /sec_met_domain="PF00881 (E-value: 9.1e-09, bitscore: 29.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLDTFLHHLHFSIDEIMPNHEVDWQDAPLPYKLYRNLPVIPLSL
                     EIPLSLPSSSTAPTLDKIGHYLWHSFGLTQLCQLNSERNVFRRSIPSGGALYPNELYIY
                     LKIDDYPDGIYHYDAAHHRLILLREGNFDSYLTDALGNRCNIHSCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRAMNHLLGLSEDEESVYA
                     VIPLSTEPNIAWFHDDHRENKTVTSHELLQQIPPLAHEHFVRSKHVNKYPMITKINAAS
                     MIESTEHFQAFAHEEYYQHSAHAIQLPKVERLSYDFLHLCKKRYSPDADFTLTKWDAAE
                     LATLLQEASLSFPYYNDVDGNSLNKNARVSLYGCFYNVKDIENGAYTYNSKTHSIQPLR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTNALGYRGYRIHQMEAGILVHKLV
                     FTATAMGMGGHPLLSFDTNSCDQLYRIDAGNETSLIQIPVGAYRARNWLKGALHN"
     gene            complement(11559..13508)
                     /locus_tag="COE07_RS03085"
                     /old_locus_tag="COE07_03085"
     CDS             complement(11559..13508)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="COE07_RS03085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03085"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_098252425.1"
                     /sec_met_domain="TIGR03882 (E-value: 3.2e-46, bitscore:
                     151.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.7e-85, bitscore: 281.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.8e-143, bitscore:
                     471.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLADYVHDQLCKQYAIIRQHTITEELPENIQLAL
                     ILHDGSPSTIHHDAELIFRSNHIPWLRAFTSFGEGIIGPYIHPPATGCTHCADGRRFIA
                     GFDQKEMWELQQKYALKAANVTRRDVRATQNGILQMCQLIHAETENILANGHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPVCSDLPNDTADAAEISLQPSLKTSTETYRCRSIHELN
                     TFLTRDYLDYRVGILNGKMQHSLLPFADVIINMPLIFGNEGVAGRTHSFAISEATAILE
                     GLERYCGMSPRGKKTNVHSSFHDLEGYALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLLQNRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLHTITGYELHAFNATMEHGIPSLWVIAK
                     NTRENGMNVVCAGGSHLDPIRALKSAIHEIAGMLLITDDELEQKREHYENCLQDPYLVN
                     KMEDHSMLYGLKEAEERLHFLLREDAPLQTFQEMNALQSFHMDLTSDLHQLLNRIHQSG
                     LEVIVVNQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPVTLGYRAEP
                     LTNEQLNPHPHPFP"
     gene            complement(13505..15424)
                     /locus_tag="COE07_RS03090"
                     /old_locus_tag="COE07_03090"
     CDS             complement(13505..15424)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="COE07_RS03090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03090"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_088231386.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1216.2,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     2.9e-56, bitscore: 181.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 4.3e-12,
                     bitscore: 39.9, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLPTHAKLKVNKDTFFLPDSSGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGHYSLDEITDGLPLPYQNRVFEIGEILYENGFVRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFETYRAANVLIVGSGYMLTSLVSSLLESGLPTFHYLVTDR
                     AETNYDRIHELIERAYEVDDCVLIQEIDTTIDRPLHEVFEPFDWILYVSQDGDIEGLRA
                     VHTICKELGKNFIPAICLANFGLAGPVVTANHEECWESAWHRLHETTLQNEHSPDSFSS
                     IPYAMLANIIVFELFKHVANDSYREKEPQFFLLNYETLEGTWHPFIKHPLATDESFTID
                     TIENLSEKLEHRSNQHASTDLFRFFDSLTSKEAGIFHVWDEQDLYQLPLSQCNIQIATP
                     LSNGPATLLPLMTCGGLTHNEARREAGLTGIETYIAEIIHRLIPEHNDIGIGAGETMTE
                     GVYRALQQHVNNKLYERQSHMLEEITTINVAEIHDKHCKFYYDALSTIHETPKIAMSDE
                     ILSFPVVWVGVNERWYGASNINMTLALRNALQLSLLHIQNEKTPYRANILPDSSIILYE
                     TDPFRVEIQAEEDIPSVQSLQLALQHLSEHNFYPFVFDLAIESFLKENLDGVYGVLIAK
                     EDSL"
     aSDomain        complement(15125..15424)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_COE07_RS03090_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.20E-57"
                     /identifier="RREFam011.1"
                     /label="COE07_RS03090"
                     /locus_tag="COE07_RS03090"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.5"
                     /tool="antismash"
                     /translation="MSNLPTHAKLKVNKDTFFLPDSSGGVYFRNNASSFRMDGDGIYNW
                     IEKLMPMFNGHYSLDEITDGLPLPYQNRVFEIGEILYENGFVRDVSQDAPHELNS"
     aSDomain        complement(15158..15397)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_COE07_RS03090_Thiopeptide_F_RRE.1"
                     /evalue="4.80E-13"
                     /identifier="RREFam004.1"
                     /label="COE07_RS03090"
                     /locus_tag="COE07_RS03090"
                     /protein_end="89"
                     /protein_start="9"
                     /score="39.9"
                     /tool="antismash"
                     /translation="LKVNKDTFFLPDSSGGVYFRNNASSFRMDGDGIYNWIEKLMPMFN
                     GHYSLDEITDGLPLPYQNRVFEIGEILYENGFVRD"
     gene            complement(15549..16808)
                     /gene="odhB"
                     /locus_tag="COE07_RS03095"
                     /old_locus_tag="COE07_03095"
     CDS             complement(15549..16808)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="COE07_RS03095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03095"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_088231385.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAAPAEQPKQETAEAPKA
                     AAPSAEQTATLQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDNERMENRPMMYLALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     gene            complement(16939..19806)
                     /gene="odhA"
                     /locus_tag="COE07_RS03100"
                     /old_locus_tag="COE07_03100"
     CDS             complement(16939..19806)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="COE07_RS03100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03100"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_098252423.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKSGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAV
                     ANSGWTGDVKYHLGREQVVSKEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFIQEQLKSDYA
                     QVPPADTSDATIHVKVPDVVAKGIQPIDTGVELDSLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGM
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDTVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVYSN"
     gene            20621..20803
                     /locus_tag="COE07_RS03105"
                     /old_locus_tag="COE07_03105"
     CDS             20621..20803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="COE07_RS03105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03105"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178300.1"
                     /transl_table=11
                     /translation="MQMMYAFGIGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLINQSL"
     gene            20937..21299
                     /locus_tag="COE07_RS03110"
                     /old_locus_tag="COE07_03110"
     CDS             20937..21299
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034130.1"
                     /locus_tag="COE07_RS03110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03110"
                     /product="hypothetical protein"
                     /protein_id="WP_098357502.1"
                     /transl_table=11
                     /translation="MNKKAIFFIGIGLLLIASITYIICNKREQVPPILVWNEQEYYVTD
                     EPAEAEEVGQKLGEVTKKIETSKQPTKDSESNILQEKTEVFEMIVEKEEKRPPIIVKEP
                     NSEEYRVARPMLKQVL"
     gene            21598..22143
                     /locus_tag="COE07_RS03120"
                     /old_locus_tag="COE07_03120"
     CDS             21598..22143
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="COE07_RS03120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03120"
                     /product="hypothetical protein"
                     /protein_id="WP_140417400.1"
                     /transl_table=11
                     /translation="MRWKEGTFEKIETNELSIEQLINTFKKQNLNGGAVISCFKVHNEN
                     FFKEIPHGEDGHEHFFRRIFNSLDIIHNLEELQIHTSDKYKFRFKEQLAVMLDGSIAAQ
                     ILWGGAYEEFKGRPVIAKQLAVNVCQYMFQDRYENIKVFESYRPWTDWFYDVAWDVTWM
                     VLDSKERKLWLICATDTD"
     gene            22302..22886
                     /locus_tag="COE07_RS03125"
                     /old_locus_tag="COE07_03125"
     CDS             22302..22886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126039.1"
                     /locus_tag="COE07_RS03125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COE07_03125"
                     /product="DUF4878 domain-containing protein"
                     /protein_id="WP_140417399.1"
                     /transl_table=11
                     /translation="MKKIKKLLLLMMVVGLTVGVLAGCAKPKATVEEFLTALQKGDIDK
                     ARTFVVSEKEFSKLNEKTEDAETKAMLSAITKNFKFEKLEEVSKNDDKAEVKVKVTSAD
                     LSVAVTKAMGEVMPMAFASAFSEDKEQSEKAMTSAIIKHLSDKDAIMATREVTLNLKKD
                     KDGDYKIVGDDNLQEVLFANAKSLEKMFGGK"
ORIGIN
        1 acggaagcag gtgtagacgg catcatcgtt ccagacttac catatgaaga acaagacatt
       61 attgccccgt tacttcgcga ggcaagcatt gcgctcattc cacttgttac cgtaacgagt
      121 cctattgaaa gaatcgaaaa aattacgagt gaatcagaag gattcgttta cgccgttaca
      181 gtagcaggcg taacgggggc acgtcaaaac tttaaaggtg agattcatag ttacttagaa
      241 aaggtaaaat cacatacgca tttaccagta gttgcaggat tcggcatttc aacaaaagaa
      301 catgtagaag aaatgattac aatatgtgac ggagttgtcg ttgggagtaa ggttattgag
      361 ctgttagaaa atgaaaaacg agaagaaata tgtgaattaa tacaggcaac aaaacaaaaa
      421 gaagaggcat aagtctcttc tttttgtttt gcgtaataaa tgttaaaata tacagaaaat
      481 acatataatt tagaggtgag aaagcatgct aagacggaaa ctactatatc ttcttttaac
      541 tgtaccacta tacgcttggc tcattagcat gacgaaaata gaggtgatgg ctctattttt
      601 agggtatgta ttcatctttt ccaacttaaa tcgcattcaa gagcaatcta ttttagaagt
      661 atgtatattt tcgattagta tagaactatt tagtatcgtt tcgattgtat tattaaatga
      721 attattccgg tggatctatt catttgaatt aataaagctt gggaatattg tattgcaagt
      781 aatatgtgct tatattgtgt ttgttatgtt agacaaaata attaggcagc agacggtttt
      841 tcaagataaa agaaactggg attaaatcaa aaaagagccg cgttggttct tttttgattc
      901 tgttataaaa acaattgaaa gtgattccat ctgttatata atagttaaaa attgtatttt
      961 aaacgaaatg agatgataac atgtccgtat tattggcact tatcccaatt atgatgattt
     1021 tcatttgttt atttttattt aaacaaacgt cattaaggtc ctcattaatt tcttatgccg
     1081 tttctgttgg aattgtttta ctctcgccaa catttcggtt agggataagt gaaactgtgc
     1141 acgcaacgat taaaggttcg ttaatttgtt ttattgttgg atacgtttta tttttcggta
     1201 tttttttatt tcacctcatg aacaaaatgg gatacatcga tcaagtagca cgttttctag
     1261 aagaagttac tcacgatcgc ttattacaaa tgctgcttat gtgttttggc atttgcccgc
     1321 ttattgaatc agtaagtgga ttcggtattg gcttcatggt cgcggcacct atttttcttt
     1381 cattaggata taaaccgttt caagctgtac tgctctcatt tatcgggtta ctagctagtt
     1441 catggggagc gatggcaaca ggtacgatta tcggttcgca gcttataaat atgccactca
     1501 cgacacttgg cacaaataca gcactattaa gtatcccgat gtttgcgtac ttcgtcattc
     1561 tttctttaca cgttgttggt ggctggaagg ctgttattga aaagtggaaa gaaggagtag
     1621 gattctttct attattttct ctcggaatct atctttctaa cgcatacgta agtgttgaac
     1681 tagcaggtat attaagctct atcgttacga ttacatttgg ctttcttatc attaaactaa
     1741 aaggaaaaag tgaacaaaat ttaataacag aacatgctgc ggcaacggag agagaagtat
     1801 ctattataaa aattattagc ccttatatat tcttaaccgt ttgtattttg ctttctcgcc
     1861 tcgttccagc attacatgat ttgctaaaat cgtatgcagt tctcgatttg aaatcatatt
     1921 cgtacaaact agaaatgcta tattcaccgg gattttggct cggtatgact tgtttattta
     1981 cgattatttt cttccgtatt ccgtctcaca ttattaaaca atcactctcg caaacgatta
     2041 aacaatggat tcctttcgct attacaacga caatgtttat tgcgattgca gaactcatgg
     2101 gggcatctgg catgcattca ttacttgcaa aaacagctgg tgaaacattt ggtacatttt
     2161 tcgttttcgt tgctccgttc attggaggga ttggcggttt tttaacaggt agtaacgcag
     2221 gatcaaatgc aatgtttata aaattacaaa tgcaaacagc acaaaacgta gcactcccgt
     2281 ggcaatacgt cacaacactt caaaacaccg catcatcagt agcgacaatc gcttgcccat
     2341 cacggattac actaggtgct tatttatgta atataccgca tcgtgaaaat gaactattaa
     2401 agaaaacgac gttaatgatt tctggtgcgg tgttgcttgt agtggtagag gttgttattt
     2461 ggtatatgtt gagaaaataa gaaatcctcc tgagaaagga ggattttctt tttatatgga
     2521 taatgcctaa agtatgaaaa gcttctactc aatgaatagg agatgaaatg tatgccctta
     2581 aaaaattatg gtgtgttaaa aggtacagtt atacaatcaa agattggaaa agggaaaaca
     2641 cctcattatc aagttcattt acagggcgag gcaggagtag actatcgtat tgcaattaac
     2701 gtaaagtcgc aaagttatcc gtcagaagtt ttatattttg caagcgacaa tattcggtca
     2761 gaggcgattc atattttacc gacgttacca tttggtttta cacaaataaa aaacaatgaa
     2821 ccgaaagtag ctttagacta cgtaagaggt aatttatttg attcaaaaca aatgattcct
     2881 ttacctgctg aaaaagcagg agtagataat gatttaaacg aaaaaataga acgttatata
     2941 aaacgagcaa tagaagaaaa agcaattatt tacgcgtttg gtgaaagatg gggaccagaa
     3001 gaaaatacac ctgattctta ctttcatttc gaaccaggaa acggtataca cgatattcac
     3061 atgaatcaag gaaatgtaga gaaatggaaa ggtgataatg gtatatggca agacggagga
     3121 atactcattc actttgaaaa ggaagaagaa tggatcggta tcttccttgc cttccagtca
     3181 cagtcatggt gtaccgatga agaagggcat gctcgtgttc cggttgagca ttgtgattat
     3241 aagagaagta attaaaggga agagctagtt cgcaatgaac tagctcttct cattatgagc
     3301 aagatatatg ttgtttaatg gtgaaattgt gtttgcaata tgaaaaacag tgatagggtt
     3361 attgtttttc atttgtatcg aataaaggcg gagacatttc ttttagtaga tttgatggaa
     3421 ttaatgtagc ggcgggaaaa tattcacttg taccgtattc ggggaaagaa aacgaagtga
     3481 ttggaccatc tattcccatt caataactta ttaaatctga taaataatta tttaaagata
     3541 gaagagggac gtcaaaacga acgccctcct cttattttat aaaacacaaa actaacaagt
     3601 gtagaaatac aagagaacag cagtgccaca ctagaaaatg caatgagata catattatat
     3661 ttcataacct gtccaattag cagattactg tcgtattgga aaagacctgc tattatattg
     3721 aataaaaata acacgataaa catgacgata acaccgtcta tcgatccttt aatgtctggt
     3781 ttacttaaag cgatatgagc agaaatacaa atggcgataa ataaaaataa ccaaaaggaa
     3841 ggattcaata aattgcttat tgtaaataag ctttttaata acacaaacgt cgacaagaac
     3901 atattctgaa ccatttctaa attaatagaa gtagaggaaa cggttgtttc gagagttgta
     3961 ttaaataaag aataagattc gggtacgaaa tagcgcatta aaaggattaa tgcagtaata
     4021 ccagaaataa tagggccaat tccaatgaag aaattcccga ttcgttgata tatgcttttt
     4081 tgattgtatt ggtgttgtac gtaacctaaa gctccttgac ttgtatctgt tgggaagaac
     4141 tgcgttgcta caattttatg acggaatagt atgcacataa tggcatgtcc gagttcgtga
     4201 ataggaacac caatccatgc agtcaaaagg aatccttttc ttccgaaagc tctcgaccaa
     4261 tacgttcttg ttagtgattc taaataacct aatagaaatc cgattacaat gatgactcca
     4321 attaaagaaa atagttggat tacacttgta aggagtattt gaaaaataga gtttacaaat
     4381 tccattgtct ttcatccaat ctgtttaaaa tgttatttgc tctgtttcat aatagcatta
     4441 tttttctaga ttgctagtct atatattttt cttcaaaagg aggagttcat aatcttcttc
     4501 ttgtagtcat gttttatgta caaagtcata tattgaattt gtaacaccct atcaggtata
     4561 tgcataagga gggatgagag catgaaatgt tcagcgtgtc atacagagaa tgcagcagag
     4621 gcaaagtttt gcgggaattg tggacattcg ttaacggaag aagtagtagc gagtggtgtc
     4681 ccagaagggg ggcatcaacc atcggcagca caagtgaagg aaacacgtcc aaatgaaaca
     4741 gtagagcaag cgaagcgatt tgcaagtggc tatttccagt tttttaaaca tgctttaaaa
     4801 gcaccgacag caattatgaa aagtggcaat attgaagtgc gaaatggaat tacaagcctt
     4861 ttacttattt gttttttagg agcatgtatt ttttatagaa taatgagcgc tggggcagca
     4921 cttacgagaa cattagcgcc agatttatct acgccttctt tctttggaga gtctataaag
     4981 gtctttttat ttttactaat tttaacttta tttgtcggat ttattatttt tgtaagtggt
     5041 aagatgatga aatcttcttt ttcgtttctt gaagtattcg gtatatgggg aacgatagcg
     5101 actccagcta ttgctatatt agtactttct tttctgttta gtttcttatt aatccttttt
     5161 ttaccgttat tattagggct ggctacaacg tatatgggaa ttagtatagt tgtagctata
     5221 gcaaaattag ataacggtgg actagatctt gtttacactc ttcttatcgc aaatgtttta
     5281 aacggaatcg tagtatggat tatattttgg tcttacttta acatgataat tcaaacattt
     5341 actggaggat taactggctt ctaaagaaaa ggtgggtgaa tggatgaatg tctgtacaaa
     5401 gtgcggaatt cagtttgaag atggtgtgca attttgtcaa aactgcggga cgaagagggg
     5461 aaatcctgta gtaaagaaga atatgaacgg tggtacaaaa gttggtatta cactgttagc
     5521 gctatttatt atagcgattg ttggattgta tttgtacgga tcatcgtatt atgcgcaggg
     5581 ggcacaagta gaccggatga ttacgatttt acaagagagg gacggggaga aattagctga
     5641 gatcatcacg gcagatgatc catcagttgt tgtaacgaga gagagtgtaa tgcctctatt
     5701 ttcgtatata aaagagaatc catcctatgt gaatgaattg aaagcatatt tgatacaagg
     5761 tgaaaaacaa ggggacggaa ttgaaagagc agatttttct ttaacgaaag acgggaagta
     5821 tttcgttata tttgatcggt atagattgaa agcgaagacg tactatacaa ctttgctttc
     5881 aaatgaaaaa ggcacatcct taaaaatgaa cggaaaagaa attgataaga cagatgacaa
     5941 aaagtttgag aagcaatatg gaccgtttct tccaggaacg caagtatttc aatcagaata
     6001 taaaaatgaa tatgtaaaac tattacgcga ggaaaaggtc gtacttatga aacaaagcca
     6061 aaataatgta acgatcgatt taacgttaca aggaaaatat attacagttc aaacgaatat
     6121 gccaggcgcg acattgtacg tgaatcaaaa accagttaca gcgctggctg gagaagaaat
     6181 tacgtgggga ccgatagcga ctgatggaag cgcgacgatt tatttagaac gaaatggaga
     6241 aagtggacgg gaaacgacga aagtagaaac ggtaacggca ctttcgtctt ataatcttcc
     6301 atttcaaaag aaaagtgaag aaaaaacagt tgtttataat gttgctccga cgcccacgac
     6361 tgggtatgta tataatggtt tcatctttcc agatagtgat attcgaaaat taacgagttc
     6421 agatttaaga tacttatcga aagaacagtt aaaaattgct agaaatgaaa tatacgcaag
     6481 gcatggacat atgtttcaaa cgaaagatat gcaagcgtac ttttcaaaac aatcttggta
     6541 tagagaaaat ccatatttta caggagtgtt gactaatatt gagtcttata atgttgaatt
     6601 aatcaaatca agagaataga atacgtgaaa aggtacagtg cataactgta ccttttttat
     6661 ggttttttat ctgaaccagg atccctagag aaaaagatgt ggaagaggaa tgtgacttta
     6721 cttgcttttc ctgatgtact tgcttgcaca tcagacaaag cactagacgt taaagcagct
     6781 tcagaatgag gggggacgat tattttgagt gcatcttctg attctgatga tatagtaact
     6841 gttattgtat catcagaaaa atttacaatt ttaacagtac caactgggaa gatggacttg
     6901 cgagcgtgtg atgcagaagc gaagcgagag gctttccaaa tcgtttgtgc aaaagtctca
     6961 tcattagata accaagcacg agcactataa atagttgcat taacggaaaa ttcttgttca
     7021 agcgggaggg cgggtctcgg ttctatcggt tcctctggaa gctggacgag aaggctggcg
     7081 cacatgtatg tttcacctac tttcaatagt tactgttata gcatattaaa catgttgttt
     7141 ataagacacg acggttacct atttacgcat agttttgtac accaaatttg tagatgaaat
     7201 attctttctt tacaataggg agaggtgtta tttttataga atatggaaat cgtaaagagt
     7261 atgtaaaata gaaggagtgg taaagtgaac tatgtcatta ttggcggaga tgcagctggt
     7321 atgagcgcag caatgcaaat tgttagaaac gataaatcgg caaatgttgt gacgttagaa
     7381 aaaggtgaaa tctattcata cgctcagtgc ggtttgcctt atgtaattag cggtgctatc
     7441 gcttcagctg aaaaattaat agcgcgcaat gtgaagacat ttcgtgataa atatggaatt
     7501 gatgcgaaag tgtgtcatga agttacaaaa gtagatacgg aaaagaagat tgtgtacgca
     7561 gagcatacga agacgagaga tgtttttgaa tttccgtatg atcgcttatt aattgcaact
     7621 ggagtgcgtc ctgttatgcc agagtgggaa ggacgagagt tacaaggtgt gcatctttta
     7681 aaaacaatcc cggatgctga gcgtatagta aaaacgctag aaacgaatga aattgagaat
     7741 gtaacgatta ttggcggcgg tgccattgga cttgagatgg cagaaacatt cgtagagctt
     7801 ggtaagaaag taagaatgat tgagcgaaac gattatgtcg gtacgattta tgatgcagat
     7861 atggcagagt atatacataa agaagcagat aaacatcata ttgaaatttt aacgaatgaa
     7921 aatgtaaaag cgtttatcgg aaaagagcga gtagaacaaa ttgaaacgga taaaggcacg
     7981 tacaaagcgg atcttgtttt agtatctgtc ggagtaaaac caaatagtga ttttcttgaa
     8041 ggaacgggta tacgtacaaa ttataaaggg gcaatcgagg taaatgcata tatgcaaacg
     8101 aatgtaaaag acgtatatgc agctggtgat tgcgccacac attaccatgt tataaaggaa
     8161 attcatgatc atatcccgct cggaacgact gcaaataaac aagggcgact tgctggactc
     8221 aatatggttg ataagcgaag agcatttaaa ggtacgttag gtacaggcat tattaaattt
     8281 atggatttga cgctcgcaag gacaggctta aatgaaaaag aagcgaaagg actaaacatt
     8341 ccgtataaaa cagtcaaagt agattctaca aatatggcgg gctattaccc aagtgccaaa
     8401 ccacttcact tgaaattatt atatcgcact gacacgaaac aattattagg cggacaagta
     8461 atgggagaag aaggcgtaga taaacgtatt gatgtgatcg caatggcact tttcaataaa
     8521 atgagtattc acgatttaga agatgtcgac ttaagttacg caccaccata taacagcgtt
     8581 tgggatccaa ttcaacaagc ggcaagaaga gcagaatagc actttttaag tgctattttt
     8641 ttgtgcaaag ggaggtaaac atcgaatttg attagaaaaa acagttaatc gatgatgaag
     8701 aatgtctctt tcaaacgttt aaaatataat gaaatggatt ctacttgtat attaatttga
     8761 aacttcactt tatttcgaat gtatcgttca cccttgaaaa catagtacgt atcgcttata
     8821 ttttcatata gtatttattt taaaagaaag caatgaacga accagggggc acagtatggc
     8881 aattaacata aaaacaatcg aagaatggat tgctgaatca aacgcaagac aggaagaaga
     8941 ctttggacgt gttgttgaag agatgaaaga agtttgcgtc ggacttgata atgcgacatt
     9001 aatttatgcg aaaaatgtat tttgtttcgg caaaaaagta gaagtattgt tcttcttcca
     9061 agaccatgtc gtaattggac aagaaacaga tgaatatgtt gaaattgaga aattaaagta
     9121 tgatgacatt acaaatagta atttaaaaac aaacgacaaa aatacaacgt tagcattaaa
     9181 gtttgctaat ggtaaatcta ttgatttaga tagcttaaat gataactacg gtacgaaaaa
     9241 ctggttattt gcgagacaaa ttaagagtat ttttaagtta atctagtaaa aagagcagac
     9301 cttttaaggt ctgcttttta tttacttcct attacacaaa ggcatccttt ttcttcataa
     9361 cattgtaccc ttgtaaatcc agtcttataa aaaaggttta ctaactcttc attcgtttta
     9421 aaattctcca tatgatattg aattttaaaa gtttcagcta ctaataaaaa agatccattc
     9481 ggttgtaaga cgcgaaatac ttcttttata tcttgttcaa catcaggcca aaagtaatga
     9541 gtttgaaaag cggtaatgag atcgaagaag tttgtattgt aaggaataga ggagacactt
     9601 gcctgatgaa tgattacttt tccttttttt acgtcctgta tattggcttt ctttgagttt
     9661 tcaacagctt gatttgaata atcaattcca tatattttcc caagtggaat ccgttttgaa
     9721 agagtatgta ttgtcttacc gcccccacaa ccaatatcta aagtaatcgc atctttacgt
     9781 atatgtattt tttgtaatcc ccaatgtgtt aatctcgtat gtgcagcgtt cataatacaa
     9841 agcatggaag aaccaattgt cccgcgagga tttttcgctt gctgaattaa ccgttgtaaa
     9901 atgctcaagt taaactctcc ttttatataa gaatatatat ttatttcgct ttttataaat
     9961 taagtccttt agaaaaagca cgccatcaat tggcgtgctt ctaattatgc aaagctcctt
    10021 ttaaccaatt ccgcgcccga tacgccccaa caggaatttg aatgagagac gtttcatttc
    10081 cagcatcaat cctgtacagt tgatcacatg aatttgtatc aaagcttagt aacggatgcc
    10141 cacccatccc catagcggtt gcagtgaaaa cgagtttatg gacaagtata ccagcttcca
    10201 tttggtgaat acggtatcct ctatagccta gtgcatttgt atagtaatct ttctttccga
    10261 ctacatgtaa gcaaagtggt acttgaaaaa ggttcacgtt atccatcgtc atactagatt
    10321 gaaggggata acgaagatct ccgtatcgaa gtggctgtat ggaatgggtt ttactgttat
    10381 aagtgtaagc accgttttct atatctttta cgttataaaa acatccatat aatgagactc
    10441 gcgcattttt atttaaagaa ttgccatcaa cgtcgttgta ataaggaaaa gagagactcg
    10501 cttcttgtag taaagtagcg agctcggctg catcccattt cgttaaagta aagtcagcat
    10561 caggggaata tcgttttttg caaaggtgta agaaatcata cgataaccgt tctacttttg
    10621 gtagctgtat ggcgtgagca ctatgttgat agtattcttc atgagcgaat gcttggaagt
    10681 gttctgtcga ttcgatcata gaagccgcgt ttatttttgt tatcatcgga tatttattca
    10741 catgctttga gcgaacgaaa tgttcatgtg ctaacggcgg aatttgctgt agtaattcat
    10801 gagaagtaac agttttattt tcacgatgat cgtcatgaaa ccaagctata tttggttctg
    10861 tacttaaagg aataactgca tacacacttt cttcgtcttc agacagtccg agtaaatgat
    10921 tcattgcccg gtctagaaat tgaaaatata cgccattcgt gtaaccgaat tgttttgcgc
    10981 attcaagcaa ttgaccgatg agaacaccac tatctaatcc ttgcagacga taagaaaagt
    11041 tattgtattt aaagaagttt ttccaaaaca tagtggatac aaatgcagca ccaaaacaag
    11101 aatgtatatt gcaacgattg ccgagtgcgt ctgtaaggta tgaatcgaaa tttccttcgc
    11161 gaagtaagat aagtcgatga tgagcggcat cgtaatggta aatgccgtct ggataatcgt
    11221 caatctttaa gtatatatac aattcattcg gatataaagc gccgcctgaa gggatagatc
    11281 ttcggaatac attcctctcg ctgtttagct ggcataattg tgttaaacca aatgagtgcc
    11341 aaagataatg accaatctta tccaaagtag gtgcagtaga agagctcggc aaagacaacg
    11401 gaatttctaa agagagaggg atgacaggta aatttcgata taatttataa ggaagcggcg
    11461 cgtcttgcca atcgacttca tgattcggca taatttcatc gatagagaaa tggagatgat
    11521 gtaaaaaagt atccagatgc atgaaatccc ctcctctatt atggaaacgg atgcggatgt
    11581 ggatttaatt gttcatttgt taacggctca gctctatatc caagtgtcac cggtacggta
    11641 tacactcgat ctaatcctgt aacacgagta aggtgatgcc cgaacgtcat cggtaacatg
    11701 cctggaatta ttacttttac acaatgtaat ccatttttct ctataagcgg taccgtttga
    11761 tttacaacga tcacctcaag tccagattga tgtattcgat ttaaaagttg atgaagatcg
    11821 gacgttaaat ccatatgaaa tgattgtaat gcattcatct cttggaacgt ctgcaatggc
    11881 gcatcttcac gtaaaagaaa gtgaaggcgt tcttccgctt ctttcaatcc gtaaagcata
    11941 ctatggtctt ccattttatt aacgagataa ggatcttgta agcagttttc gtagtgctcc
    12001 cttttttgct cgagttcatc gtctgttatt agtaacatgc ctgctatttc gtgaatggca
    12061 ctctttagag cacggattgg atctaaatga gagcctcctg cacaaacaac gttcatccca
    12121 ttttcacgag tatttttcgc aattacccat aagctcggga tgccgtgttc catcgtcgcg
    12181 ttaaaagcat gtagttcata tccagtaatc gtgtgtaacc gctggatcat taattgtagt
    12241 tctgtatcat ttgctgaact aagatcaagg cggggaagag gtaattcagc ataccaagtg
    12301 agcaggaagg cgtcacgctc tacaatttct aaaatgccgt gaaaaatagc ttcttctaaa
    12361 ctaccaccaa ttgcacatcc attcgatgtt tcatacacga aagcatctcg atgaccgagg
    12421 ctataataag caatggattc aggaactaaa agtggcctgt tttgtaataa agaatagccc
    12481 catacccagt tttgctcata atcaggatcg aatggtttaa acgggaaact atcacgatta
    12541 tagtgttcat ttgtatgtac accgagggtg agaggattca gtgcataacc ttctaaatca
    12601 tgaaaactac tatgcacatt tgtctttttc ccgcggggcg acataccgca atatcgttct
    12661 aatccttcta aaatcgcagt tgcttcactt attgcaaatg aatgagttcg acctgcaaca
    12721 ccttcatttc caaatattaa aggcatgttt ataataacgt cagcaaaggg taataaagaa
    12781 tgttgcattt ttccgttcaa tataccaacc cggtaatcta aataatctct cgttaaaaat
    12841 gtgtttagct catgaatgga acggcagcga tacgtttcag tacttgtttt taagctcggt
    12901 tgtaaagaaa tctctgctgc atccgccgta tcattaggta aatcactaca tacagggcag
    12961 agaggatcag gaagaaaaga atgccgcgta cattgcaatg tttgtaagtt tagtaaaatg
    13021 agttcatttt ctaaagaaga atgtccgtta gctaatatat tctccgtttc agcatgaatg
    13081 agctggcaca tttgtagaat accgttttgg gtggcacgta catcacgtct cgtcacgttc
    13141 gctgctttta gcgcatattt ttgctgtaat tcccacattt ctttttgatc aaatccagcg
    13201 ataaagcgtc gtccatcggc acaatgggta catccagttg caggaggatg aatgtaagga
    13261 ccgataatac cctcaccaaa tgaagtaaat gcacgtagcc acggaatgtg gttggaacga
    13321 aaaatcaact cagcatcatg atgaatagta gaaggggagc cgtcatgtaa tatgagagcg
    13381 agttgaatat tttcaggaag ttcttctgtg atagtatgtt ggcgaatgat agcgtattgt
    13441 ttgcataatt gatcatgtac gtagtctgca agtaggccat ctcctataag caatatattt
    13501 tgagtcatag actatcctcc tttgcaatta ataccccgta cacaccatct aaattttctt
    13561 tcaaaaatga ttcaattgct aaatcaaata cgaatggata aaaattatgt tccgataaat
    13621 gctgtaaggc aagctgtaaa gattgcacac ttggaatgtc ttcttctgct tgtatttcca
    13681 ctctaaaagg gtccgtttca tataaaataa tagatgagtc aggcaaaata ttagctctgt
    13741 aaggagtctt ttcattttga atatggagaa gtgatagttg tagtgcattt cgtaatgcta
    13801 acgtcatatt aatattcgat gcaccatacc atctctcatt tacaccgacc caaacgacag
    13861 gaaaactgag aatctcgtca ctcattgcta ttttaggtgt ttcgtggatt gtagaaaggg
    13921 catcgtaata aaacttacaa tgcttatcat gaatttccgc tacgttgatt gttgtaatct
    13981 cttctagcat atgtgactgc cgttcataca gtttattgtt tacatgttgt tgtagagccc
    14041 ggtatacacc ttctgtcatc gtttccccag cgccgatacc gatatcgtta tgttcaggaa
    14101 taaggcgatg aatgatttct gctatatatg tttcaattcc tgttaaacca gcttctcggc
    14161 gcgcttcatt atgggtcaat cctccacaag tcataagagg gaggagggta gccgggccat
    14221 ttgatagtgg cgtagctatt tgaatattgc attgtgataa cggtaattga tataaatctt
    14281 gttcatccca cacatggaat ataccagctt ctttagaagt taacgagtcg aaaaaacgaa
    14341 ataaatcagt tgaagcatgt tggttggacc gatgctcaag tttttcggaa agattttcta
    14401 tcgtatcgat tgtaaaactt tcatcagtag caagagggtg ttttataaaa ggatgccatg
    14461 ttccttcgag tgtttcatag tttaataaaa agaattgtgg ttccttttct cggtaagaat
    14521 cattcgcgac gtgtttaaat aactcaaaaa cgattatatt tgctaacatt gcatatggaa
    14581 tagaagagaa ggaatctggt gaatgttcat tttgcaaagt cgtttcatgt agccgatgcc
    14641 atgctgattc ccagcactct tcatgatttg ccgttacgac agggccggcc aaaccgaaat
    14701 ttgctaaaca aatggctggt atgaagtttt ttcctagttc cttgcaaata gtgtgaacgg
    14761 ctcttaaacc ttcaatatct ccatcttgag aaacgtacaa aatccagtcg aaaggttcga
    14821 atacttcatg caggggacga tcaattgtcg tatctatttc ttgaatcagt acacaatcat
    14881 caacttcata tgcacgttct attagctcat gaattctgtc ataatttgtt tcagcacgat
    14941 ctgtaacgag gtaatgaaat gtaggtaaac cagattcaag taaagaagaa actaaggaag
    15001 taagcatata tccggaacca actataagga catttgctgc gcggtacgtt tcgaatttta
    15061 aagcacctga atgagaatca gcttctagaa attcaatttg cgaagcgtat ctatcaagta
    15121 atgcactgtt taattcatga ggcgcatctt gacttacatc acgaacgaaa ccattttcat
    15181 ataaaatctc tccgatttca aatacacgat tttgataagg gagagggagt ccgtctgtta
    15241 tttcatctaa agaataatgc ccgttaaaca tcggcattaa tttttcaatc cagttataaa
    15301 ttccatcacc gtccatgcga aatgaactgg cgttatttcg aaaatagaca cccccgcttg
    15361 agtcagggag aaagaaagta tccttattta ctttaagttt tgcatgagtt ggaaggttac
    15421 tcattttaat cctccttacg ttttaggcat acattattaa cgtatgtcat gtgatttgtc
    15481 cagtatgaac gcaataaaaa aggctgtaga atgattcatt ctacagcctt gaatagactt
    15541 ttagtctatc aaccttctaa taataatgat tttggatctt caagcatatc tttaacagca
    15601 acaaggaagc taaccgcttc tttaccatca acaatacggt gatcgtaaga taaagcaagg
    15661 tacatcattg ggcggttttc catacgctcg ttatcgattg caactgggcg tacttggatt
    15721 ttatgcattc ctaaaatacc tacttgtggg ctatttagga ttggtgttga cattagagaa
    15781 ccgaacacac caccgtttgt aattgtaaat gtaccacctt gtagttcttt taatgaaagt
    15841 ttgttatcgc gtgctttcat acctaaatta cgaatttcgc tttcgatttc agcgaagttt
    15901 aattggttag catcgcgtac aactggaaca actaatccat ctggagctgc tactgcaata
    15961 ccgatatcat agaatttttt aatgataagc tcgtcacctt gaatttcagc atttaataat
    16021 gggaattgtt ttaatgctgc aacaactgct tttgtgaaga atgacatgaa accaagacgt
    16081 acatcatgtt ttttctcgaa agcatctttg cgctctttac gtaattccat gatcgcactc
    16141 atatcaactt cgttaaatgt tgttaacatt gcagatgttt gttgaacttc tacaagacgt
    16201 tttgcaattg tttgacggcg gcgggacatt ttcacgcgct caactggttt ttcgaattca
    16261 gtttttgcaa ctggagcagg agctggactt tttggagcag ctggtgcttc ttttggtgct
    16321 gcagcatgag cttgtacatc gtgtggtctc acacgtccaa gtggatctgt gctacgtacg
    16381 tcgtttaagt cgattcctaa ttcacgagcc atttttctag cagctggtga tgcgatagga
    16441 cggtttgtat ttggtaaacc ttgtagagtt gcagtttgtt cagcacttgg agctgctgct
    16501 ttcggtgctt cagctgtttc ttgttttggt tgctcagcag gtgctgcagg tgtacttact
    16561 gcaactggtg ctccgtttgc atctaaaatt gcgatagttg cgccaacttc aactgtatcc
    16621 ccaggttcgc ctagtaattt cgatacaata cctgaatctt ctgcaatgat ttctacattg
    16681 actttatcag tttcaagctc aacaacgctg ccacctttct caactttgtc gcctacgttg
    16741 ataagccatt gtgagatagt tccttctgta atagattctg caagctcagg tactttaatt
    16801 tcgatcattt taaatgtcct ccccttattt gcctaacggt gtgttttttc ttcttttgtc
    16861 ttcggtaatc tccatttgtt agcctgaccc tgggcagata ttctgcccaa ggcaagctag
    16921 aaaccttcat tcttactttt agttgctgta aacttcaatt tcttgtttat cttgacggaa
    16981 gttatacttc acatctaaag catgtgcaac aattagttct tgctcagctt tatgagcgaa
    17041 tggatcgcca ccagatgggc tagaacggtc tgggcgtcca atgtaacctg ttttcactgt
    17101 atctccagct agttcgaaca gaattggagc catgtaatgc caagcgccca tattacgagg
    17161 ttcttcttga acccaaatga tttcttctaa gtttttaaag cgtttaataa tagattgaac
    17221 tttctcagca gggaatgggt acaattgttc aatacgaaca acatgaactt catctaagtt
    17281 gtattcatgt ttaccagact cgatttctgc tgctaagtca atcgccattt tacctgtact
    17341 taaaacaaga cgttttactt tgtttggttt catgccaagg ttttcttgtt ctaaagcagg
    17401 ttggaaacgt ccttcgctta actgactagc agttgaaagc gtaagtgggt gacgtaataa
    17461 actcttcggc gtcatcagta ctaatggtcg aacagcttct gttcctaaga tagatgcttg
    17521 acgacgtaag atatggaagt actgtgccgc gctcgttaag tttgcaactg tccagttgtt
    17581 ctcagcagct aactgtaaga aacgctctgg acgtgcgcta gagtgctctg gtccttgacc
    17641 ttcataaccg tgtggtaata gaagaactaa accagatttt tgaccccatt ttgctcttcc
    17701 agctgaaaca tattgatcaa ataatgcttg cgcagtattt gagaagtcac cgtactgtgc
    17761 ttcccacata acaagcgttt ctggagcgaa tacgttataa ccatactcgt aaccaacaac
    17821 agcagcctct gataacggac tgttatgaac agagaatgaa gcgttaatgt ttggtaagcg
    17881 atgtaatggt gaatatgttt catttgtatc cgtatcatgt aatacgatat gacggtgcgc
    17941 gaatgtacca cgctgtgaat cttgaccagt taaacgaatt ggcgtacctt cttgtaaaat
    18001 agaagcgaat gctaatgact cagcaagtgc ccattcaatt ttaccgttct cttctagagc
    18061 atctttacgg cgctctagaa ttttcttcac cttcggatat acgttaaatc cttctggcca
    18121 agataataaa ccttcattaa ttgcacgaag tgaatcaagc tcaacaccag tatcgattgg
    18181 ctgaatgcct tttgcaacaa catctggtac tttaacgtga atcgttgcat cgctcgtatc
    18241 agctggtggt acttgtgcat agtcagattt taattgttct tgtataaact gtgtaatcgt
    18301 ttcaacctca tctgcattta gaacaccagc agcttgtaat tgatctgcat aaattgctct
    18361 tacagtagga tggtttttaa tttttttgta tacttgtggt tgcgtaactg ctgggtcatc
    18421 catttcgtta tgaccgtagc ggcgataacc aattaaatcg atcaagaagt cttttttgaa
    18481 caacatgcga tattggatcg caaggttagc agcagcaaga caagcttctg gatcatcagc
    18541 gttcacgtga acaatcggaa tatcgaaacc ttttgcaagg tcacttgaat atttcgtaga
    18601 acgagaatca tagctatcag tcgtaaaacc aactgcattg tttgcgataa catgaattgt
    18661 tccgcccgtt tgatacgcgt tcaatctgct taagttcaac gtttcagata caataccttg
    18721 accagggaat gcagcatcac catgaactaa aattacgaat gactttgaag tatcttgttc
    18781 tggaagacca gattttttac ggttttcttg agctgcacgt gcgaaacctt ctactacagg
    18841 attcacgaac tcaagatgac ttgggttatt tgctaatgta acgcgagtac taacttcttc
    18901 tttactaacg acttgttctc tacctaaatg gtatttcacg tcgccagtcc agccagaatt
    18961 tgctactgcg ccttctattt ttgcatgttt gaactcagca aacatgtgac tatatggttt
    19021 ttctaatacg tgtgcaagta cgcttagacg accgcggtga gccataccaa tcatgacatc
    19081 ttctacgccg ctcttagcac cttctagaac aatctcatct agaacaggta caagcatatc
    19141 aacgccctcg atagagaaac gcttttgccc aacgaatgtt ttatgcaaga attgctcgaa
    19201 accttcaacc gctgttaaac gttttaaaag agcagttcgt tttttatttg atagtggttg
    19261 acgcaatgaa tttgattcca ccatttgatg caaccacgcg cgttcttcac tatcttgtat
    19321 atgagaaaat tcataagcta aagattttgt ataaacgtct tttaatctat gaattacatc
    19381 aagtgcagtg tgaatacctt ctggtgcatc ttgccatact gtttttgctg gaatcgcttt
    19441 caaatcagca tcgctaagtt cgttcattgc tttctcaaga agagattgtc catttgcagc
    19501 atcttccatc gggttgatgt gagccaacgt atgcccgaaa gaacgaatct gctcaacaag
    19561 ttgaacgact ttaagaattt tttcaatgtt ccctgtgttt tgaggagaaa aatgtgttgc
    19621 tgtgttgtcc cctgttacga catcatcttg aaacgaagga gctccaaaaa tttcaaaaag
    19681 ctcttgtaat tccggatcaa cagaacctgc tccagttacg taaagatcat actgctcaat
    19741 aacataacca aggttcggac cgtggaactt ggcccaaggg tttgtcgttg tattcttcct
    19801 cgtcatttgt ttaaacctcc caatgcatat aatccttttc catacaaagg tgcattttgc
    19861 tctttttcaa taattgatta actaataaat aatgtaattg ttttctttac tcttatgtta
    19921 ttacaataat ttacataata ccaaacacta ttacttatct gttttgtaaa aaaacattca
    19981 caataactta tcacccaagt taatctttca tgttataaag taattttaca gaaaaatggg
    20041 gtggatatat ttggtatacc tatactaata actataattg ttgcatttaa atataggtat
    20101 aatagttaga atgtttcgat aaaatgtagt tcgaattatg tatattgaaa taataagcgc
    20161 tttcattgat attatacaac aatataacgg aatatagtat aaaaaataaa aaattatgaa
    20221 tttatcgtaa actttatttc gatagtgtta aatatcgaaa ggaaaacgaa ggatttctac
    20281 aaaaaaagtg gctaaacata aaaaatgctc cataacccgt tagtttctat caatatgccg
    20341 aaaaacaacg taaaaccaat aacgcatttt atgaaataaa gaggagaatg gaatacttta
    20401 aaaggataaa acaaatatgg agatattaaa ttttcacaaa agtggggagg ggatatagta
    20461 acggatatat acattgttcc atgtttcgtt tcaaaataga catgctgaaa atgaaaagtt
    20521 tcttctatat ttatggcact cacaatgagt accgtcttta tctcatttgt tgttttggca
    20581 aaaagatatt aagatggaaa agagaaagga agattaacat atgcaaatga tgtatgcttt
    20641 tggcattggg cttgtattat ttttagccgt attcttattt attcgtaaag acgttcaagg
    20701 cgggacgtta acgaaaagag gattttataa aatgattggc tgtttagttg ttatgtttat
    20761 agcgattatc gtaatgatcg ttttaataaa tcagtcactg taacattgaa aaatggaacc
    20821 ttacttatgt aaggtttttc tttttgaaaa caaaacaaaa attaccataa aaacaattta
    20881 ctatctatat cctatattat ataatccaat aaaatgatag ataaggagaa tagtatatga
    20941 ataaaaaagc tatcttcttt ataggaatag gtctactact tatagctagt atcacttata
    21001 taatatgtaa caaacgagaa caagtaccac ctatattagt atggaacgaa caagaatact
    21061 acgttacgga tgaacctgcc gaagcagaag aagtcggaca aaaacttggc gaggtaacaa
    21121 agaaaattga aacgagcaaa cagcctacta aagacagtga gtccaacata ttacaagaaa
    21181 aaacagaagt atttgaaatg attgtagaaa aagaggagaa aagaccaccc ataatcgtaa
    21241 aagagcctaa tagtgaagaa tatagagtag caaggccgat gctaaagcaa gtattataat
    21301 gaaaaggaga cttatatgca ggcagtaatt tcatatccgt ggtcgttaag ggaaatattt
    21361 gtctttttcc tgtgctttat cattcctcct atcggtgcta tttacatttt gatgaataga
    21421 gaggcgctgc aaaagagaga cttcatttta taggtagcgg ggcatgatct acttagctta
    21481 attgttatta ttttttcgaa tatgaataag agataaccca gtaatcttaa agttgctggg
    21541 ttttattttg ctatttataa tgaagaaata aatttttcat agagagtagt gagcggtatg
    21601 agatggaaag agggaacttt tgaaaaaata gaaacaaatg aattatctat tgagcagctt
    21661 ataaacacat ttaagaaaca aaatttaaat ggtggagcgg taataagctg ttttaaagtg
    21721 cataacgaaa attttttcaa agaaatacca catggagaag atggacacga gcactttttc
    21781 agaagaatct tcaactcttt agatataata cataacttag aagagttaca aatacataca
    21841 tcagacaaat ataagtttcg ttttaaagag cagctggcag tcatgcttga tggtagcatt
    21901 gccgctcaaa ttttatgggg cggagcgtac gaagaattta agggaagacc agttatcgca
    21961 aagcaattag cagttaatgt atgccaatac atgttccaag atcgatacga aaatattaaa
    22021 gtgttcgaaa gctaccgccc ttggacagat tggttttacg atgttgcgtg ggatgttact
    22081 tggatggttt tagatagtaa ggagcgtaaa ttgtggttaa tttgtgctac ggatacggat
    22141 tgatagaaga ggagccttgt aggaatgctg caaggctctt tttatttttt gaaggaatag
    22201 aaaacaaatc atataaatga tatgtcgaaa aatgttttta atgtaagttt tatactattg
    22261 tatagtgctg gattactaga aaagataaga ggagaatgaa cgtgaaaaag ataaagaaat
    22321 tattgctgct aatgatggta gtaggattaa cagtcggtgt tctagcagga tgcgcaaagc
    22381 cgaaagctac tgttgaagaa tttttaacag cgttacaaaa aggtgatata gacaaggctc
    22441 gtacatttgt tgtaagtgaa aaagagttca gtaaactaaa tgaaaaaaca gaagacgctg
    22501 aaacaaaagc aatgctaagc gcaattacga agaactttaa atttgaaaag ctagaagaag
    22561 tatcaaaaaa cgatgataaa gcagaagtga aagtaaaagt aacatctgcc gatctatccg
    22621 ttgccgtaac aaaagcaatg ggagaagtta tgccaatggc cttcgctagt gcctttagcg
    22681 aagataaaga gcaatctgaa aaagcaatga catcagctat catcaaacac ttatcagata
    22741 aagatgcaat aatggcaact cgcgaagtta cattgaattt aaagaaagat aaagatggtg
    22801 actacaaaat cgttggtgat gataacttac aagaagtgtt gtttgctaat gcgaaatctt
    22861 tggagaagat gtttggtggg aagtgattga gttcttgtaa aagagtgata gttatacaac
    22921 gttagagtga gaatttgaaa gtagtaaaaa agatgtcagc atttgctggc atctttttta
    22981 tgtaatttat aaaaatgtgg ttataaagag tgattaaagt ttcactttat ttgcttgtat
    23041 atactatgtt ccaagaatat tcaagatttt cgatgtttgt ttcagctttt tgataatctt
    23101 ctgtagctga ttttaagaga tattcataat ccagttcact gttctcagta tttccgtcaa
    23161 attgtttcat cattttaagt tgcttctcaa gagacgattt taaattattg atagattcac
    23221 cgattaattt aaattcttta tcagaaaagg aattgggata tttactaaag tttttttcta
    23281 ttctttgtat agttggatac gtatacttct caatactttc aataccctct cgagcttgct
    23341 taataatctc ggcttcaggc gaggatttat ctatagaaac gagtgttgcc aaatcgttat
    23401 tgctgtggct taagttcact tcatctaaaa tattgtggaa atcgtccatt agtatagcct
    23461 gataaataac gtttccgctt gtaaggtttt tattcgctcc ggttgctt
//
