LOCUS       NZ_MTJS01000005        26382 bp    DNA     linear   CON 23-AUG-2024
DEFINITION  Lactococcus lactis strain 537 contig_4, whole genome shotgun
            sequence.
ACCESSION   NZ_MTJS01000005
VERSION     NZ_MTJS01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 39603)
  AUTHORS   Ho,V., Lo,R., Bansal,N. and Turner,M.S.
  TITLE     Characterization of Lactococcus lactis isolates from herbs, fruits
            and vegetables for use as biopreservatives against Listeria
            monocytogenes in cheese
  JOURNAL   Food Control (2017) In press
REFERENCE   2  (bases 1 to 39603)
  AUTHORS   Lo,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2017) School of Agriculture and Food Sciences, The
            University of Queensland, Hartley Teakle Bldg (No. 83), Slip Rd, St
            Lucia, Brisbane, QLD 4072, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. Jun 2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1036.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563475.1-RS_2024_08_23
            Annotation Date                   :: 08/23/2024 15:27:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,579
            CDSs (total)                      :: 2,519
            Genes (coding)                    :: 2,482
            CDSs (with protein)               :: 2,482
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 14 of 37
            Pseudo Genes (incomplete)         :: 23 of 37
            Pseudo Genes (internal stop)      :: 8 of 37
            Pseudo Genes (multiple problems)  :: 7 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:09:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 120
            Orig. end                         :: 26502
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MTJS01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26382
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     cand_cluster    1..26382
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26382
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16382](-)"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16382)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     misc_feature    16..29
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.74"
                     /tool="antismash"
     gene            complement(44..535)
                     /locus_tag="BW154_RS11870"
                     /old_locus_tag="BW154_11880"
     CDS             complement(44..535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865170.1"
                     /locus_tag="BW154_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11880"
                     /product="hypothetical protein"
                     /protein_id="WP_038602405.1"
                     /transl_table=11
                     /translation="MTYYLEEEGFENLFSEMKPIVMKLMKQIRIRTWKIEDYLQEGMII
                     LHLLLEEQSDGQKLHTKFKVKYHQRLIDELRRSYAKKRSHDHFIGLDVYECSDWINSGD
                     TSPDNEVVFNHLLAEVYEGLSAHYQDLLLRQMRGEELTRMERYRLREKIKAILFSEDEE
                     "
     misc_feature    588..597
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(794..2524)
                     /gene="ezrA"
                     /locus_tag="BW154_RS11875"
                     /old_locus_tag="BW154_11885"
     CDS             complement(794..2524)
                     /codon_start=1
                     /gene="ezrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132670.1"
                     /locus_tag="BW154_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11885"
                     /product="septation ring formation regulator EzrA"
                     /protein_id="WP_021723359.1"
                     /transl_table=11
                     /translation="MSSTVIILIVVLLVILVAFYAFAILMRKKTEDRILALEERKESLF
                     DLPVQEEIDSVKKMHLVGQSQTIFREWNQKWLDLSSNSFADLEEHIFEAEQLNDSFHFF
                     RARESVADSEAQIELMEGDVEGIRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNA
                     DLYGTVITELEKHLANIETEFSQFVTLNSTGDPIEAAEVLETAEEHTIALRAITEQIPS
                     FIKTIEKDVPKRLDELQEASDKFVAEEYILPDNVNIKERMDDLHDHLVESSSLLEQFEL
                     DRVEAELGLIQEKVEELYAIFEREYSARRNVEKRSSVLKEYIEHIRANNKNLLLEIDHV
                     TQAYILSGNEKGYVRGYQEHLESLDSDVDEILGNIQAKTMPYSILSRRVNSVVNALEDI
                     EKNQIKISDTLTGLRDEERAAQEIAERFDSELRTIKRYVEKCNLPGLPKDYLDLFFTTG
                     DRVQNLFKELGRVRINIDTINHLVDVSTEDMHVLKEATTNLTDHAVLAEQLIQYANRYK
                     AANEQVAQGISRALQLFENSRDYDGSFDEISKTLELVEPGAASRISGVYFKNKPTPDYL
                     "
     gene            complement(2729..3757)
                     /gene="tsf"
                     /locus_tag="BW154_RS11880"
                     /old_locus_tag="BW154_11890"
     CDS             complement(2729..3757)
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tsf"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906339.1"
                     /locus_tag="BW154_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11890"
                     /product="translation elongation factor Ts"
                     /protein_id="WP_010906339.1"
                     /transl_table=11
                     /translation="MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGI
                     AKAAKKADRVAAEGLTGIAVNGNVAAIVELNSETDFVAKNDQFVALVKETAELIASKKP
                     ATNEEALALETASGITLEAELVQATATIGEKITFRRFAVIEKTDAQHFGAYQHNGGKIG
                     VVSVVEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLV
                     NKPELPHHEFGSKSQLTEEVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTK
                     VDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKA
                     GL"
     misc_feature    complement(3803..3816)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.97"
                     /tool="antismash"
     gene            complement(3879..4646)
                     /gene="rpsB"
                     /locus_tag="BW154_RS11885"
                     /old_locus_tag="BW154_11895"
     CDS             complement(3879..4646)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906340.1"
                     /locus_tag="BW154_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11895"
                     /product="30S ribosomal protein S2"
                     /protein_id="WP_038602408.1"
                     /transl_table=11
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMKPYIFTERNGIHVIDLQK
                     TVKLVDDAYNYVKNASQEGAVVLFVGTKKQAAEAVKEEALRAGQYYVNHRWLGGMLTNW
                     NTIQTRVTRLKEINKMEEEGTFEVLPKKEVVLLNKERERLEKFIGGIADMPRIPDVIYI
                     VDPHAEQIAVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDAIRAVKLITAKMADAII
                     EGRQGEDAAEDFVAEEAASEESLEELAEIVEGK"
     gene            5005..6030
                     /locus_tag="BW154_RS11890"
                     /old_locus_tag="BW154_11900"
     CDS             5005..6030
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865172.1"
                     /locus_tag="BW154_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11900"
                     /product="lactonase family protein"
                     /protein_id="WP_038602411.1"
                     /transl_table=11
                     /translation="MKEKILLGGYTKRVSKGVYSVLLDTKAAELSSLNEVAAVQNPTYI
                     TLDEKGHLYTCAADSNGGGIAAFDFDGETATHLGNVTTTGAPLCYVAVDEARQLVYGAN
                     YHLGEVRVYKIQANGSLRLMDTVKHTGSGPRPEQASSHVHYSDLTPDGRLVTCDLGTDE
                     VTVYDVIGEGKLNIATIYRAEKGMGARHITFHPNGKIAYLVGELNSTIEVLSYNEEKGR
                     FARLQTISTLPEGYHGANGVAAIRISSDGKFLYTSNRGHDSLTTYKVSPLGTKLETIGW
                     TNTEGRIPRDFNFNKTENYIIVAHQESDNLSLFLRDKKTGTLTLEQKDFYAPEITCVLP
                     L"
     misc_feature    6073..6091
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.9"
                     /tool="antismash"
     misc_feature    6162..6177
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(6229..6244)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            6262..8973
                     /gene="adhE"
                     /gene_synonym="adhC"
                     /locus_tag="BW154_RS11895"
                     /old_locus_tag="BW154_11905"
     CDS             6262..8973
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006066 - alcohol metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="adhE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /gene_synonym="adhC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003132664.1"
                     /locus_tag="BW154_RS11895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11905"
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="WP_003132664.1"
                     /sec_met_domain="Aldedh (E-value: 8.5e-20, bitscore: 61.8,
                     seeds: 89, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 7.3e-109, bitscore:
                     355.0, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKKAAPAAKKVLSAEEKAAKFQEAVAYTDKLVKKAQAAVLKFE
                     GYTQTQVDTIVAAMALAASKHSLELAHEAVNETGRGVVEDKDTKNHFASESVYNAIKND
                     KTVGVISENKVAGSVEIASPLGVLAGIVPTTNPTSTAIFKSLLTAKTRNAIVFAFHPQA
                     QKCSSHAAKIVYDAAIEAGAPEDFIQWIEVPSLDMTTALIQNRGLATILATGGPGMVNA
                     ALKSGNPSLGVGAGNGAVYVDATANIERAVEDLLLSKRFDNGMICATENSAVIDASVYD
                     EFIAKMQEQGAYMVPKKDYKAIESFVFVERAGEGFGVTGPVAGRSGQWIAEQAGVKVPK
                     DKDVLLFELDKKNIGEALSSEKLSPLLSIYKAETREEGIEIVRSLLAYQGAGHNAAIQI
                     GAMDDPFVKEYGEKVEASRILVNQPDSIGGVGDIYTDAMRPSLTLGTGSWGKNSLSHNL
                     STYDLLNVKTVAKRRNRPQWVRLPKEIYYEKNAISYLQELPHVHKAFIVADPGMVKFGF
                     VDKVLEQLAIRPTQVETSIYGSVQPDPTLSEAIAIARQMKQFEPDTVICLGGGSALDAG
                     KIGRLIYEYDARGEADLSDDASLKELFQELAQKFVDIRKRIIKFYHPHKAQMVAIPTTS
                     GTGSEVTPFAVITDDETHVKYPLADYQLTPQVAIVDPEFVMTVPKRTVSWSGIDAMSHA
                     LESYVSVMSSDYTKPISLQAIKLIFENLTESYQYDPAHPTKEGQKARENMHNAATLAGM
                     AFANAFLGINHSLAHKIGGEFGLPHGLAIAIAMPHVIKFNAVTGNVKRTPYPRYETYRA
                     QEDYAEISRFMGFAGKDDSDEKAVQALVAELKKLTDSIDINITLSGNGVDKAHLERELD
                     KLADLVYDDQCTPANPRQPRIDEIKQLLLDQY"
     gene            complement(9311..9808)
                     /locus_tag="BW154_RS11900"
                     /old_locus_tag="BW154_11910"
     CDS             complement(9311..9808)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012898640.1"
                     /locus_tag="BW154_RS11900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11910"
                     /product="nitroreductase family protein"
                     /protein_id="WP_098394218.1"
                     /sec_met_domain="PF00881 (E-value: 1.6e-10, bitscore: 32.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLEELIQLRKSNKFHNIGVNVESVIEVVKKSYYNFEKHSVPSA
                     GAIYGLKVLLFYKNNKKIFNSKGEISAEKFEINQIKKTCFYDDKYFSSSSILIAVTYDY
                     DKYFGKYGNCGIRYASIECGAFLQNFQLLLSEKEIYGCPLGFVDNDALLGIEEPLIYFI
                     IN"
     gene            complement(9795..10004)
                     /locus_tag="BW154_RS11905"
                     /old_locus_tag="BW154_11915"
     CDS             complement(9795..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011677212.1"
                     /locus_tag="BW154_RS11905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11915"
                     /product="hypothetical protein"
                     /protein_id="WP_098394219.1"
                     /transl_table=11
                     /translation="MKYKLNPLFTLRKTDKAVFNFSRAELTQFNDTGFDILLAVLEQEN
                     DREWTDDEDEFLKELIKEKIVEES"
     gene            complement(10001..10828)
                     /locus_tag="BW154_RS11910"
                     /old_locus_tag="BW154_11920"
     CDS             complement(10001..10828)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427187.1"
                     /locus_tag="BW154_RS11910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11920"
                     /product="radical SAM protein"
                     /protein_id="WP_098394220.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-12, bitscore: 38.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.8e-17, bitscore: 54.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.4e-10, bitscore: 30.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRDDELFLPIKVYIYLTNHCHYECDYCFLKEMKMLNTKEISKED
                     LEKIAYYLEKYKVPLVAICGGDPILHPKLIDFVQLLSEHKNYPTIATNAVDVSYEYSYQ
                     LKSAGIRYLQIGIDSLQYSKLDNYKENGHLRKVEKTVKYLKELGILYGFATCVTRKNIG
                     ELSKIASYAKETGAELLKLSTYDGENQVYKLTEIQKEELKIFVRQYNTDGIYVRYSPVQ
                     ETLNYVSEYPSLTIYANGDLAIEETGDVIGNISTSEPAVEYKKYILEKWRTNK"
     gene            complement(10821..12020)
                     /locus_tag="BW154_RS13310"
     CDS             complement(10821..12020)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BW154_RS13310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_230315137.1"
                     /transl_table=11
                     /translation="MTQFFNGQKILFINRILFDDAFITVVEVIFFSVYLKLSFSDFSSI
                     MGLCLLISLLVQIPTGYLSDKFDRKLMLVLGNGAEIVCLITLLFLPSLIKGSLFIPVLI
                     IEIIRTGMLALASGNFEVLIFNMFKREGKTEKDFMEKSASYFSIGAIIAAISGFVSTVL
                     FSYLVILPLILDLSIKIIKLLSAIFMCSEAIHKEMTKIKMKVKFLNHKLLFLLFSLALL
                     FCISRGTFSLYQPVMTSLGIPLYYYGLLIMIVNLSIFVLLRVLKKKVSLFKLSTLLLVS
                     FAVLTFQGVLVIEHFIPGNLFRFLIVAIIFSSMQIIRLFSEGLSSYFINTAIKDRDDKT
                     TIFSLYSTMAQLLLSASFFLMGVVQGGVDNYLMTYLYISAIFVLIIMALVIFGKGKKYV
                     "
     gene            complement(12017..12943)
                     /locus_tag="BW154_RS13315"
     CDS             complement(12017..12943)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.5"
                     /locus_tag="BW154_RS13315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_229049653.1"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-37, bitscore:
                     121.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-10, bitscore: 32.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-22, bitscore: 71.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 9.5e-08, bitscore: 22.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINYLKNPLFLTWMLTNKCNLRCKFCYLEDYQGKELELDEINQVL
                     DIIQDKEFTHVSLLGGEPTECEYFEYIIIQLEKLRISYSFSTNGQKLFRNEELIRILSK
                     SKYLKEVQISLESPQKLINDAVRGKGTFESAIKSVALLVKENVPTRLAMVVTKENNSTI
                     QQMIDMCATLGCRELRLMPFMPMGTGLLEKERLFMDYEGLVRACSDLKIPDNLIVTTYL
                     KEENTAETLGCGAGTAACVINSDLTLSACPVVSQTQKSIEKLGNDGSSFDYIWGTSSIF
                     NIWRAGKYRKSTSCNLCPLFEECGGYQ"
     gene            complement(13046..13903)
                     /locus_tag="BW154_RS11920"
                     /old_locus_tag="BW154_11930"
     CDS             complement(13046..13903)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017865177.1"
                     /locus_tag="BW154_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11930"
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_098394221.1"
                     /sec_met_domain="TIGR01716 (E-value: 1.3e-30, bitscore:
                     97.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNLKTGIIIAFIRETKHLKLKEMTGGDFSESQLAKFEKGETEI
                     TVGKLFTVLENSNVYLDEFQNLYNEYEQSDEYNYRHELAVAYAQKNIKVIKEIQNFWEE
                     KCQQKPDNKFYQINKIVVKINLAMAKGSTVFKEDTDLLMNYLESVSEWGRYELWVFGNC
                     LRHFDDNALKYYGMQILGKSNYYHSIHLNQQIVIRTFLNLIDTWLRRENLMQAFKYINH
                     LKEIGIGINFFYEKILFEYHKAHYKVLQKQNGAIEEMKKHAQTLADYGFPLEAKVLFEE
                     IEKL"
     gene            complement(14014..15153)
                     /locus_tag="BW154_RS11925"
                     /old_locus_tag="BW154_11935"
     CDS             complement(14014..15153)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012898644.1"
                     /locus_tag="BW154_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11935"
                     /product="MFS transporter"
                     /protein_id="WP_012898644.1"
                     /transl_table=11
                     /translation="MKIIIKYKQLFLFKLFLSLLPYFFISILIMNALGYRYSEIMIISA
                     MTQIIGVILNLPLGIYAEQKNRKKVLLLNNILSIIAFTLFLFEKFYLAILAAVILGISE
                     ALSSGVMQTFSYEQFPDDVTYRKYLEGSSSIQYLAISVMTIITPAILHFNRFLPIIISV
                     AFIVFSTIFLCFIKLEKREEKQEEKITINIRTLRKGLKVSSKLNLFILLGITVTTLIMS
                     VNSWSSILLKYHYFPLKYLGLVLFTFNVCMAIGSRIKWKKLSIVMLLPLISILLFFTKS
                     VFTTIVLFSIFRLINGGYNNFFIGEFNKLIKNNRVVFWSIYDTFLSLFFIFADLSSGLI
                     AQNLTVEFIYLIFGLISLLILLIYLLARKNIYFRKIKNY"
     gene            complement(15150..16382)
                     /gene="kwcM"
                     /locus_tag="BW154_RS11930"
                     /old_locus_tag="BW154_11940"
     CDS             complement(15150..16382)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="kwcM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573366.1"
                     /locus_tag="BW154_RS11930"
                     /note="This protein, a peptide-modifying radical SAM/SPASM
                     domain protein, cyclizes KxxxW-containing RiPP precursor
                     peptides by creating a Lys-to-Trp crosslink.; This protein,
                     a peptide-modifying radical SAM/SPASM domain protein,
                     cyclizes KxxxW-containing RiPP precursor peptides by
                     creating a Lys-to-Trp crosslink; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BW154_11940"
                     /product="KxxxW cyclic peptide radical SAM maturase"
                     /protein_id="WP_257140087.1"
                     /sec_met_domain="Fer4_12 (E-value: 9.1e-08, bitscore: 23.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.2e-16, bitscore: 50.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.9e-14, bitscore:
                     44.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1e-09, bitscore: 30.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESESIFLSLVKEMGKEKAFNEYIKYFNADSLTKILREKIYKKG
                     EIEEKEVSSFSIINKIQSKIKELKKLNQMSFPLELVIYPSMYCNLHCGFCFLANREDEN
                     VHLADDWKKILSQAKENGILSFSILGGEPTKYKDIDNLLKIIDSLKVVTTITTNGQEIK
                     KSTIDIICQSDYITPVISLESIDDFKNFELMGTRAKRGIELIKLFHERKKKVRLNTVYS
                     NQSEEDIMELLKFAIKNEIDRFSIADYSEVTGFTKITKIYNISDLRKLEEKVRRYLLDN
                     KIDNFNFSVEGCFYFTAFPELIEEGKNLSEFENMYFGCRAKHTKKEILSNGDVLPCIAF
                     LGEKHTSNAFHQTLAEIWKNDSNYTEVREFKTENKDCLKCSMLRICEGGCYPKLQRTLN
                     PNFTKDKTCQL"
     misc_feature    16675..16688
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(16676..16689)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            complement(16768..17796)
                     /locus_tag="BW154_RS11935"
                     /old_locus_tag="BW154_11945"
     CDS             complement(16768..17796)
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427190.1"
                     /locus_tag="BW154_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11945"
                     /product="SepM family pheromone-processing serine protease"
                     /protein_id="WP_003132657.1"
                     /transl_table=11
                     /translation="MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLG
                     KMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSHFNSFTSIYSEQEMTGGLNDAQFNR
                     VNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAVNGQ
                     QFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEV
                     VTTPKVTVNAGSIGGPSAGMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGV
                     DKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKKLKTKMKIVPVKTIQDALDYL
                     EK"
     gene            complement(17783..18280)
                     /gene="coaD"
                     /locus_tag="BW154_RS11940"
                     /old_locus_tag="BW154_11950"
     CDS             complement(17783..18280)
                     /EC_number="2.7.7.3"
                     /GO_function="GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906348.1"
                     /locus_tag="BW154_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11950"
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="WP_010906348.1"
                     /sec_met_domain="CTP_transf_like (E-value: 5e-21, bitscore:
                     66.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKIGLFTGTFDPLTNGHLDVIKRASQHFDQLYVGIFKNDQKNP
                     LFPTDKRVEMLEEALTSLSVTHKVKVIKHERDLTVNIAKKLGVTALVRSLRNSQDLEYE
                     KNMFYFNMEMTGIETIFFLAKPELEPLNSTRMRELHAFGQDVSAWVPENVSRELRKLDE
                     KK"
     gene            complement(18328..18867)
                     /gene="rsmD"
                     /locus_tag="BW154_RS11945"
                     /old_locus_tag="BW154_11955"
     CDS             complement(18328..18867)
                     /EC_number="2.1.1.171"
                     /GO_function="GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427191.1"
                     /locus_tag="BW154_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11955"
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="WP_179884653.1"
                     /transl_table=11
                     /translation="MRVVSGNYGGRPLKTLAGKTTRPTTDKVKGAIFNMIGPYFEGGRV
                     LDLFAGSGSLAIEAISRGMDHAILVEKDRAAQQVILENIKMTKEPEKFQLLKMSAERVL
                     SNVSETFDLVLLDPPYAKEQIVENLELLQDKKRLTENVIVVCETDKEVELPNQIGKLEL
                     TRQKTYGISKISIYEF"
     misc_feature    complement(18867..18880)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.19"
                     /tool="antismash"
     gene            complement(19038..20258)
                     /locus_tag="BW154_RS11950"
                     /old_locus_tag="BW154_11960"
     CDS             complement(19038..20258)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427192.1"
                     /locus_tag="BW154_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11960"
                     /product="MFS transporter"
                     /protein_id="WP_039116754.1"
                     /transl_table=11
                     /translation="MKDFFGLHPTLKIRLIMNFFGTLCFSTVGGSMTIYYNKYMGAGIT
                     GLLLVISSVMVFLVGLYAGHLSDVQGRRPVMIFSTAITGFGGALATFANSSFYFNPWVT
                     FLGFLIINFGFGFFNTASQAMIVDLTTSENRRVVYSIQYWIINFAIMIGSGLSGWFFRD
                     YLVWLLLAITIEEIVSCLVVIFWIDESFNPDTQQHKQESNIIKAYFTVAKDRIFMYYLF
                     ASVFIAMIFNQIDYYLPVHLSDSFRTARIFGIEVYGQRMLTIFLMVNTLVIVLFMGRVN
                     KLTKNWSRSSGISIGIILQGLGFMIAFLGRDLTWELIAALIATIGEMILVPFSQALRAD
                     LMDGDQVGTYTGAFSVTQPIASVLSGILVSLSSLYGNIGMTIFMFFIIVLGVLPSLRAI
                     RMHESHS"
     misc_feature    20275..20288
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.11"
                     /tool="antismash"
     gene            complement(20342..21568)
                     /gene="lmrP"
                     /locus_tag="BW154_RS11955"
                     /old_locus_tag="BW154_11965"
     CDS             complement(20342..21568)
                     /codon_start=1
                     /gene="lmrP"
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836081.1"
                     /locus_tag="BW154_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11965"
                     /product="multidrug efflux MFS transporter LmrP"
                     /protein_id="WP_098394223.1"
                     /transl_table=11
                     /translation="MKEFWNLDKNLQLRLGIVFLGAFSYGTVFSSMTIYYNQHLGSAIT
                     GILLALSAVATFVAGILAGFFADRNGRKPVMVFGTVIQLLGALLAIGSNLPGHVNPWST
                     FIAFLLISFGYNLVITAGNAMIIDASNAENRKVVFMLDYWAQNLSVILGAALGAWLFRP
                     AFEALLVILLLTVLVSFFLTTFVMTETFRPIVKTKEEAENIFQAYKTVLQDKTYMIFMG
                     ANIATTFIIMQFDNFLPVHLSNSFKTITFLGFEIYGQRMLTIYLILACVLVVLLMTTLN
                     RLTKDWSHQKGFIWGSLFMAIGMIFSFLTTTFTPIFIAGIVYTLGEIVYTPSVQTLGAD
                     LMNPEKIGSYNGVAAIKMPIASILAGLLVSISPMIKATGVSLVLALTEVLAIILVLIAV
                     NRHQKTKIN"
     gene            21756..22250
                     /locus_tag="BW154_RS11960"
                     /old_locus_tag="BW154_11970"
     CDS             21756..22250
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010906351.1"
                     /locus_tag="BW154_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11970"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_058206114.1"
                     /transl_table=11
                     /translation="MVNLKEYENDVNDYAIEITKYLISRGSQLVDAEDAVQDTLVKILS
                     LDIFIEPDKLRAFMYRTSIRTYINSYNRSKHYQKIIKNLEKELETAAFLVESSPLPKII
                     EQLSPYYKELLNAYYYENCSTKQLAEYFECSLSKIKIDLYRARKKLKKQLEKAGYDQWL
                     L"
     gene            22274..23380
                     /locus_tag="BW154_RS11965"
                     /old_locus_tag="BW154_11975"
     CDS             22274..23380
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836082.1"
                     /locus_tag="BW154_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11975"
                     /product="anti-sigma factor C-terminal domain-containing
                     protein"
                     /protein_id="WP_058206113.1"
                     /transl_table=11
                     /translation="MRTLLIFPYFVLALTLFFGLIRLFIFAINKTRHKLQTTESISNLN
                     KDFHNFALKTKIKRWGLTTWIALTVFSAFIVVGWRVNSAIMEKNFFKTFDYSTAIFTAS
                     APNVAYNNQIIDDYGVFSSNLHSDTYKDIDGYHVPWESYNFSFNVSNVGGLSLNTLSPS
                     VNSNAYFTQTTNQKIASFFSTNANYKSKDYNGILPTHDADKISQLSNHVAEVAVTFDKA
                     YSYNEIQKMIPENLLINWYWIGYNDSKSLDAAGQTNWFGLMSNSNYAENGNNSQLTGKL
                     DNTTYQDFKKSVAAIAKKNQITINDFSPSKDALKQVKKYPTLKSAKFSGVILTGQTKNF
                     VNFDKNSWVYASNVGLTVELRPDIKPLK"
     gene            complement(23476..24822)
                     /locus_tag="BW154_RS11970"
                     /old_locus_tag="BW154_11980"
     CDS             complement(23476..24822)
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /locus_tag="BW154_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11980"
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_010906353.1"
                     /transl_table=11
                     /translation="MAHIKFDYSKLTPFVAENELDEIQWQIDGAAKLLHEGKGAGSDYI
                     GWLDLPEDYDKEEFARIQKAAKKIQSDSEVLIVIGIGGSYLGARAAIDFLSNSFVNLQT
                     AEERKAPRILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFEEMLV
                     KKYGREEANKRIYATTDKEKGAVKVNADANNWETFVVPDSVGGRFSVLTAVGLLPIAAS
                     GADITALMEGANAARKEYTSTNVHENDAYAYAALRNILYRKGKFSEILINYEPSLQYFS
                     EWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQWIQEGTRTVFETAIRIEKPRKNINI
                     PELDADLDGLGYLQGKDVDFVNKKAADGVLLAHTDGNVPNMIVTLPEQDEFTLGYAIYF
                     FELAIGVSGYLNGINPFNQPGVEAYKKNMFALLGKPGFEELSKELNDRL"
     gene            25166..25672
                     /locus_tag="BW154_RS11975"
                     /old_locus_tag="BW154_11985"
     CDS             25166..25672
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015427194.1"
                     /locus_tag="BW154_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW154_11985"
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="WP_021467077.1"
                     /transl_table=11
                     /translation="MMKYTFEIDLDRYKNLAQQKQKTHKKFLAGLAKKPPKQLDKIVKE
                     VHEEVFLEIDCTKCANCCKTLGPLWTEADIERVAKHLKMKVSDFEAAYLRTDEDGDKVF
                     QTMPCPFLGSDNLCSIYEVRPKACREFPHTDRKKIYQINNLTIKNTLYCPAAYEFVEKL
                     SYRLK"
     misc_feature    25989..26003
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
ORIGIN
        1 atcaaaaaat tccctatttt taataaaaat agggaactct ccttcattct tcatcttctg
       61 aaaataagat ggcttttatt ttttcacgaa ggcgatatcg ttccatacga gttaattctt
      121 ctcctcgcat ttgtcgaagt agtaagtctt gataatgtgc gctcaaacct tcatatactt
      181 ctgccagcaa atgattgaag accacttcat tatctggact agtatcacct gaatttatcc
      241 agtctgagca ttcataaaca tctaaaccta taaaatggtc atggcttcgt ttctttgcat
      301 aactccgtct tagctcatca attaatcttt gatgatactt taccttaaat tttgtatgca
      361 gcttttgacc atcgctctgc tcttctaata gaagatgtaa aataatcatc ccctcttgaa
      421 gataatcctc tattttccat gttctaatac gaatttgttt cattaatttc ataactatag
      481 gtttcatttc tgaaaacaga ttttcaaaac cctcttcttc caagtaatat gtcattggaa
      541 agttctcctt ttatattatc tttatttgat taattagtaa gatgatagaa ggcggcgagt
      601 gtatgtctaa taaacagtca gggagcatct tattataatg agctattttc atatctatcc
      661 tttcaagaca tttttatggc ttttatttca ttataataat ttttaagtgt tttacctaac
      721 gatattatgc gaatattcag aatttataaa ccaataaata aaagcaaggc tattaacctt
      781 gcttttactt attttataag taatcaggag taggtttatt tttaaaataa actcctgaaa
      841 ttctagaagc tgcacctggt tctacaagtt ctagcgtttt tgaaatttca tcaaatgaac
      901 catcatagtc acggctgttt tcaaataatt gaagcgctct tgagatccct tgtgctactt
      961 gttcatttgc agctttataa cgattggcat attgaatcaa ttgttcagct aatactgcat
     1021 ggtcagtcaa attagtcgtt gcttctttta aaacgtgcat atcttcagtg cttacgtcaa
     1081 caagatgatt aattgtatca atgttgattc taactcgtcc taattctttg aaaagatttt
     1141 gtactcgatc tcctgttgtg aagaacaagt cgagataatc tttaggaaga ccagggagat
     1201 tacatttttc aacataacgt tttattgtac ggagttcaga atcaaagcgt tccgcaattt
     1261 cttgagctgc tctttcttca tctctgagtc ctgtgagggt atcactaatc ttaatttggt
     1321 tcttctcaat atcttcaagg gcattgacta ctgaatttac tctacgtgaa agaattgagt
     1381 aaggcattgt tttagcttga atatttccta gaatttcatc aacatctgag tcaagagatt
     1441 ctaaatgttc ttgataacct ctaacatatc ctttttcgtt tccagaaagg atataggctt
     1501 gtgtaacatg gtcaatttca aggagaagat ttttattatt tgctctgata tgttcaatat
     1561 attctttgag aactgatgaa cgtttttcaa catttcgacg tgcgctatat tctctttcaa
     1621 aaatagcata aagttcttca actttttctt gaattaaacc aagttcagct tctactcgat
     1681 ctagttcaaa ttgttctaat aatgaactac tttcaacgag atgatcatgt aaatcatcca
     1741 ttctttcttt aatgttgaca ttatcaggaa gaatgtactc ttctgcaacg aatttatcac
     1801 tcgcttcttg taattcgtca agtcgtttag gaacatcttt ttcaattgtt ttaataaatg
     1861 atggaatttg ctctgtaatt gcacgtaaag caatcgtatg ttcttcagca gtctccaaaa
     1921 cttcagccgc ttcaatcgga tctcccgttg agtttagcgt tacaaactga gaaaattctg
     1981 tttcgatatt ggctaaatgt ttttcaagtt cagtaataac cgttccatac aaatctgcat
     2041 tgtcagcaat atcgctacgt aagttatcat ataaatcaag ggattcttga attttatttg
     2101 aattacgctt ttcttgttca acaagttgag caacaccttg acgaattcct tcgacatcac
     2161 cttccattaa ttcaatttgt gcctcactat ccgctacaga ttcacgagca cggaaaaaat
     2221 ggaatgaatc gtttaattgt tcagcttcaa aaatatgttc ttccaaatca gcaaaagaat
     2281 ttgatgataa gtcaagccat ttttggttcc attcacggaa aatcgtttgc gattgtccga
     2341 caagatgcat ttttttaaca gaatcaattt cttcttgaac aggcaaatcg aaaagcgatt
     2401 cctttcgctc ttctaaggct agtatacggt cttctgtttt ctttcgcatt aatattgcaa
     2461 aagcataaaa ggctacgaga ataactaata agacaacaat gaggataatg acagtacttg
     2521 acatgcttta ctccataaaa tgatttaatt acttaaaaat agtttaatta cttaggttag
     2581 atagatttta aatagataga aaatctcaaa tataattata gcatattgcg tcaaagaaat
     2641 acactatttt cttagttttc taaccgaaaa gccgtttttt attttcaaaa taaaaaaagc
     2701 aacctccaga ggctgctttt taattaaatt aaaggcctgc ttttgccgct tcaacttctg
     2761 ctgcaaagtc tgtttcagct ttttcaattc cttcaccaac ttcaaaacgt gtgaatgcaa
     2821 ttgctttagc tccttttgat tcaaggaaag cttcgactgt tttgctgtca tccatgatgt
     2881 aaagttgtgc aagaagagca aattgttggt caacttttgt attgtcaacg atgaatttag
     2941 ccattttacc tggaagaatt ttgtcccaga ttttttctgg ttttccttca gctttaagtt
     3001 cttcttcaaa tgaagctttc gctgctgcaa gaacttcttc tgtcaattgg ctcttagaac
     3061 caaattcatg gtgtggaagt tctggtttgt taacaagtac acggctagcg ttgtcttcat
     3121 caatcttgtg gttcatttgt gctaattctg ctttaacaaa ttctgaatca agttcatcag
     3181 ctgaaagaac agtagggttc attgcagcga tatgcattga cacttgttta gcaagtgttt
     3241 catctgcacc ttcaacgaca gaaacaaccc caattttacc accgttatgt tggtaagctc
     3301 caaagtgttg agcatcagtt ttttcaatta ctgcaaaacg acggaaagtg attttttctc
     3361 cgattgtagc agtcgcttga acaagttctg cttcaagagt aatccctgaa gctgtttcaa
     3421 gtgccaatgc ttcttcgtta gttgctggtt ttttagacgc aataagttct gctgtttctt
     3481 taaccaaggc aacaaattga tcatttttag ctacgaagtc tgtttctgag ttcaattcaa
     3541 caatcgctgc aacatttccg tttacggcaa ttcctgtaag tccttcagcg gctacacgat
     3601 cagctttttt agctgctttc gcaatccctt tttcacgaag aagttctgct gctgcttcca
     3661 tatttccgtc agtttcaaca agagcgcgtt tagcgtccat gattcctgca ccagtttttt
     3721 cacgtaattc ttttacttga gctgctgtta ctgccatttt gtaaatctcc tatgtgtttt
     3781 tttctgtcag tattgacagt agttttattt aaaaaaacag gtgaggcgta aggcctcgcc
     3841 tgttgtagtt acttaattag tataagttga agttaaaatt atttaccttc aacgatttca
     3901 gcaagttctt caagtgattc ttctgaagct gcttcttctg ctacgaaatc ttccgctgca
     3961 tcttcacctt gacgtccttc aatgatagcg tctgccattt tagctgtaat caatttaaca
     4021 gcacggatag catcatcatt tgcagggata actacgtcga ttggttctgg atctgcgttt
     4081 gtgtcaacca ttgctacaac tgggattccc aaagttttag cttctttaac tgcgatttgt
     4141 tcagcatgtg ggtcaacgat gtagataaca tctggaatac gaggcatatc agcgatacca
     4201 ccgatgaatt tttcaaggcg ttcgcgttct ttgttaagaa gaactacttc tttcttaggt
     4261 aaaacttcga aagttccttc ttcttccatt ttgttgattt ctttaaggcg tgtcacacgt
     4321 gtttggatag tgttccagtt agtgagcata ccacccaacc aacggtggtt tacgtagtat
     4381 tgaccagcgc ggagagcttc ttctttaact gcttctgcag cttgtttttt agtaccaaca
     4441 aaaagaacta ctgcaccttc ttgtgaagcg ttttttacat agttgtaagc atcgtcaaca
     4501 agttttacag ttttttgaag gtcgataacg tggataccat tacgttctgt gaagatgtat
     4561 ggtttcattt tcgggttcca acgacgagtt tggtgaccga agtgaacacc agcttcaaga
     4621 agttgtttca ttgaaataac tgacatgtta atgtctcctt ttaaaatagt ttttcctctt
     4681 tcatctgtca tccgcagccg caatacttgc gtacactacg actttgtcga gacgaaatgc
     4741 gagatggttg catagcaact ctatcattat acattgtttg acctattttt gcaagtatct
     4801 attcatgctt ctattgttca gtaaatctat ttttctagcc actcctattg tctgacaaat
     4861 ctaattgtta atttagactc tataatcact aaaagagtaa gttttcaaac ttttttctaa
     4921 gaaaaaaatt aatatttttg ctgaaaccgc tttttttgtg ataaaataat tatagtaaat
     4981 aaattagttt gtgaggagag aaatatgaaa gaaaaaatcc ttttaggcgg ctatacaaaa
     5041 cgtgtatcta aaggcgttta tagtgttctt ttggacacta aagctgctga attatcatca
     5101 ttaaatgaag tcgctgcggt tcaaaacccc acttatatca ctctcgatga aaagggacac
     5161 ctctatactt gcgcagcaga tagtaatggt ggaggaatcg ccgcctttga ttttgatggc
     5221 gaaactgcca ctcatctcgg aaatgtcaca accacgggag ctccactctg ctatgttgcc
     5281 gtggacgaag cgcgccaatt agtttacgga gcgaactatc atcttggaga agttcgtgtt
     5341 tataagattc aagctaatgg ctcactccga ttaatggata cagttaaaca tactggttct
     5401 ggaccacgtc ctgaacaagc tagctcacac gttcattatt ctgatttaac tcctgacgga
     5461 cgccttgtca cctgtgattt gggaacagat gaggtcactg tttatgatgt cattggtgaa
     5521 ggtaagctca atatcgctac aatttatcgt gcagaaaaag gaatgggtgc tcgtcatatt
     5581 actttccatc caaatggtaa aatcgcttat ttagttggag agttaaattc aacaatcgaa
     5641 gttttaagtt ataatgaaga aaaaggacgt tttgctcgtc ttcaaacaat tagcacccta
     5701 cctgaaggtt atcatggagc aaatggtgtt gctgccatcc gtatttcatc tgacggtaaa
     5761 ttcctctata cttctaatcg cggacatgat tctttgacaa cttacaaagt aagtcctctc
     5821 ggtacaaaac ttgaaacgat tggctggaca aatactgaag gtcgtatccc tcgtgatttt
     5881 aatttcaaca aaactgaaaa ttatatcatt gtcgctcatc aagaatctga taatctatct
     5941 cttttcttac gagataaaaa aaccggtact ttaactttgg aacaaaaaga tttttacgct
     6001 cctgaaatca cttgcgtttt accactataa aaatttattt tttcacaaag ttcgactgat
     6061 aaactagaaa agattgctaa ttcctctcaa aaaattggca atcttttttt cttcaataaa
     6121 gattgttata aaccgttttc taaactttcg atgagcattt ttgtaaaaat tatcacaata
     6181 ttgcttgaca tctataaaaa actttgttaa actattcacg taaaagaaag tgaatgaaat
     6241 cacaaaggag aacctacaaa tatggcaact aaaaaagccg ctccagctgc aaagaaagtg
     6301 ttaagcgctg aagaaaaagc cgcaaaattc caagaagctg ttgcttatac tgacaaatta
     6361 gtcaaaaaag cacaagctgc tgttcttaaa tttgaaggat atacacaaac tcaagtcgat
     6421 actattgtcg ctgcaatggc tcttgcagca agcaaacatt ctctagaact cgctcatgaa
     6481 gccgttaacg aaactggtcg tggtgttgtc gaagacaaag ataccaaaaa ccactttgct
     6541 tctgaatctg tttataacgc aattaaaaat gacaaaaccg ttggtgtcat ttctgaaaac
     6601 aaggttgctg gatctgttga aatcgcaagc cctctcggtg ttcttgctgg tatcgttcca
     6661 acaactaatc caacatcaac agcaatcttt aaatctttat tgactgcaaa aacacgtaat
     6721 gctattgttt tcgctttcca cccacaagct caaaaatgtt caagccatgc agcaaaaatt
     6781 gtttacgatg ctgcaattga agctggtgca ccggaagact tcattcaatg gattgaagta
     6841 ccaagccttg acatgactac cgccttgatt caaaaccgtg gacttgcaac aatccttgca
     6901 actggtggcc caggaatggt aaacgccgca ctcaaatctg gtaacccttc actcggtgtt
     6961 ggagctggta atggtgctgt ttatgtcgat gctactgcaa atattgaacg tgccgttgaa
     7021 gaccttttgc tttcaaaacg ttttgataat gggatgattt gtgccactga aaattcagct
     7081 gttattgatg cttcagttta tgatgaattt attgctaaaa tgcaagaaca aggcgcttat
     7141 atggttccta aaaaagacta caaagctatt gaaagtttcg tttttgttga acgtgctggt
     7201 gaaggttttg gagtaactgg tcctgttgcc ggtcgttctg gtcaatggat tgctgaacaa
     7261 gctggtgtca aagttcctaa agataaagat gtccttcttt ttgaacttga taagaaaaat
     7321 attggtgaag cactttcttc tgaaaaactt tctcctttgc tttcaatcta caaagctgaa
     7381 acacgtgaag aaggaattga gattgtacgt agcttacttg cttatcaagg cgctggacat
     7441 aatgctgcaa ttcaaatcgg tgcaatggat gatccattcg ttaaagaata tggcgaaaaa
     7501 gttgaagctt ctcgtatcct cgttaaccaa ccagattcta ttggtggggt cggagatatc
     7561 tatactgatg caatgcgtcc atcacttaca cttggaactg gttcatgggg gaaaaattca
     7621 ctttcacaca atttgagtac atacgatcta ttgaatgtta aaacagtggc taaacgtcgt
     7681 aatcgcccac aatgggttcg tttgccaaaa gaaatttact acgaaaaaaa tgcaatttct
     7741 tacttacaag aattgccaca cgttcacaaa gctttcatcg ttgctgaccc tggtatggtt
     7801 aaatttggtt tcgttgataa agttttggaa caacttgcta tccgcccaac tcaagttgaa
     7861 acaagcattt atggctctgt tcaacctgac ccaactttga gcgaagcaat tgcaatcgct
     7921 cgtcaaatga aacaatttga acctgacact gtcatctgtc ttggtggtgg ttctgctctc
     7981 gatgctggta agattggtcg tttgatttat gaatatgatg ctcgtggtga agctgacctt
     8041 tctgatgatg caagtttgaa agaacttttc caagaattag ctcaaaaatt tgtcgatatt
     8101 cgtaaacgta ttattaaatt ctaccatcca cataaagcac aaatggttgc aattcctact
     8161 acttctggta ctggttctga agtgactcca tttgcagtta tcactgatga tgaaactcat
     8221 gttaagtacc cacttgctga ctaccaatta acaccacaag ttgccattgt tgaccctgag
     8281 tttgttatga ctgtaccaaa acgtactgtt tcttggtctg gtattgatgc gatgtcacac
     8341 gcgcttgaat cttacgtttc tgttatgtct tctgactata caaaaccaat ttcacttcaa
     8401 gcgatcaaac tcatctttga aaacttgact gagtcttatc aatatgaccc agcgcatcca
     8461 actaaagaag gacaaaaagc ccgcgaaaac atgcacaatg ctgcaacact cgctggtatg
     8521 gccttcgcta atgctttcct tggaattaac cactcacttg ctcataaaat tggtggtgaa
     8581 tttggacttc ctcatggtct tgccatcgcc attgctatgc cacatgtcat taaatttaac
     8641 gctgtaacag gaaacgttaa acgtacccct tacccacgtt atgaaacata tcgtgctcaa
     8701 gaggactatg ctgaaatttc acgctttatg ggatttgctg gtaaagatga ttcagatgaa
     8761 aaagctgtgc aagctctggt tgctgaactt aaaaaattga ctgatagcat tgatattaat
     8821 atcacccttt caggaaatgg tgtcgataaa gctcaccttg aacgtgaact tgataaattg
     8881 gctgaccttg tttatgatga tcaatgtact cctgctaatc ctcgtcaacc aagaattgat
     8941 gagattaaac agttgttgtt agatcaatac taataatctg ttgataaaaa taataaaaac
     9001 gctctgatga attcgtcaga gcatttttta ttatagctta tacaactatc aaaaggtata
     9061 aatcaatttc gatataggct cttttcactc cattgattta tatttctata aaaatcaata
     9121 attaattagc gatagaagtc gagttcatgc atgctaataa tgaaattgtt ttaaattctg
     9181 gtttttcttt atgttctttg cgaacatctt tcacagtttc tttgttcatg aaaattcatc
     9241 cttattgtgg tactattttg agcccaaata gttatataag aatcctaaac ttcggatatc
     9301 ttatcaaaga ttaattaata ataaaataaa ttaggggttc ttctattccc aacagagcat
     9361 cattatctac gaagcctaat ggacaaccgt atatctcttt ttctgaaagt agtagttgaa
     9421 aattttgcag aaaagcacca cattcgattg aagcatacct tatcccacaa ttaccatatt
     9481 taccaaaata tttatcgtaa tcatatgtca cagcaataag aattgaactt gaagaaaaat
     9541 atttatcatc ataaaaacaa gtttttttaa tttgatttat ctcgaatttc tctgcactta
     9601 tctccccttt agagttaaat atttttttat tgttcttata aaaaagtaaa actttcaaac
     9661 catatatagc tccggcagaa ggaacgctat gtttctcaaa attatagtag gattttttta
     9721 ctacttctat tacactttca acatttacac caatattatg aaatttattt gattttctta
     9781 gttgaataag ctcttcaaga ttcttcaacg attttctcct tgattaactc tttcagaaat
     9841 tcatcttcat catctgtcca ctctctatca ttttcttgtt caagaactgc caataaaata
     9901 tcaaaacctg tatcgttgaa ttgtgttaat tccgcccttg agaaattgaa gactgcttta
     9961 tctgtttttc tgagcgtaaa taatgggttt aatttatact tcatttattt gttctccatt
    10021 tttctaatat atatttttta tattctacag ctggttcaga agtggaaata tttccaataa
    10081 catctcctgt ttcttcaatt gctaaatccc cgtttgcata tattgtcagg gagggatatt
    10141 ccgatacata atttaatgtt tcttgaacag gcgagtagcg tacataaatc ccatcagtat
    10201 tatattgtct tacaaagatt tttaactctt ctttttgaat ttctgttaat ttatatactt
    10261 gattttctcc atcataagtt gaaagtttca acagttcggc tcctgtttct ttagcataac
    10321 tcgcaatttt actaagctct ccaatatttt ttcgagtgac acaagttgca aaaccatata
    10381 atatccccaa ttcttttaaa tatttcacag ttttttcaac ttttctaaga tgcccgtttt
    10441 ctttgtaatt atccaatttt gaatattgca aactatcaat gcctatctgt aaatatcgaa
    10501 ttcctgctga ttttaactga tatgaatact cataggatac gtcaactgca ttagtcgcta
    10561 tagttggata attcttatgt tctgatagta attggacaaa atcaataagt tttgggtgga
    10621 gaattggatc tcccccacaa atagcaacta atggtacttt atatttttct aaataataag
    10681 ctattttttc taaatcttct tttgagatct cttttgtatt taacatcttc atttctttaa
    10741 ggaagcagta atcacattcg taatgacaat gattagttaa atatatatac accttaattg
    10801 gtaaaaaaag ttcgtcatct ctaaacatat tttttcccct ttccaaagat aactaaagcc
    10861 ataataatta ggacaaaaat tgcactaata tataaatagg tcatcaaata gttatcaact
    10921 cccccttgaa caacccccat caggaagaaa gaagcagata gtaaaagctg ggccattgta
    10981 gaataaagag aaaaaatagt tgttttatcg tctctatcct taatcgcggt gttgataaaa
    11041 taagaggaga gtccttctga aaatagtctg ataatctgca tacttgaaaa tattatcgct
    11101 acaatcaaaa aacgaaaaag atttcctggt ataaaatgtt caattaccaa tactccttga
    11161 aaagtaagaa ccgcaaaaga aacaaggagt aatgttgaaa gtttgaacag cgatactttc
    11221 tttttcaaaa ctctcaaaag aacgaatatc gacaggttca ctatcataat aagtaggcca
    11281 taataataaa gaggaatacc taatgaagtc ataactggtt ggtataaaga aaatgtcccc
    11341 cttgaaatac aaaataaaag ggcaagcgag aacaagagaa ataacaattt atgatttaag
    11401 aactttactt tcatttttat ttttgtcatt tctttatgta tcgcttcaga acacatgaaa
    11461 atagcagata ataatttgat gatttttatc gataaatcca atataagtgg caaaatcact
    11521 agataggaaa atagaaccgt ggaaacaaat ccagaaattg ctgctataat cgctcctatg
    11581 gaaaaatatg aggctgattt ctccataaaa tctttttcag tttttccttc tctcttaaac
    11641 atattaaata ttaacacttc aaaattacca ctcgctaaag ccaacatgcc tgttcttata
    11701 atttctataa ttaaaactgg aataaataaa gagcctttta tcaaactagg aagaaaaagt
    11761 aaagttataa gacacacaat ttccgcacca tttcctaata ctaacattaa tttcctatcg
    11821 aacttatcgg ataagtaacc tgttggaatc tgaactaaca acgaaattaa caaacataag
    11881 cccataatac ttgaaaaatc tgaaaaagaa agctttaaat acacactgaa aaatataacc
    11941 tctacaaccg ttataaatgc atcatcaaaa agtattctat ttatgaataa aattttctga
    12001 ccattgaaaa attgagtcat tggtaccccc cacattcctc aaatagcgga cataagttac
    12061 acgaggttga ttttcgatat tttcccgctc tccatatatt aaaaatcgaa cttgttcccc
    12121 atatgtaatc aaaacttgaa ccatcgttac ctaatttttc gatagatttt tgggtttgag
    12181 atactacagg acaggctgaa agtgtcaagt cactatttat aacgcaggca gctgttccag
    12241 caccacaacc taaagtttca gcggtattct cttcttttag gtaagttgtg acaattagat
    12301 tatctggtat ttttaaatct gagcatgctc gaactaaacc ttcataatcc atgaataggc
    12361 gttctttttc taataatccc gttcccatgg gcataaatgg cattaatcgc aattctctac
    12421 accctaatgt ggcacacata tcaatcattt gttgaatggt agaattattt tcttttgtca
    12481 cgaccatagc aagccgtgta ggaacattct cttttactaa tagtgctaca ctttttattg
    12541 cactttcaaa tgttcctttc cctctgactg cgtcattgat taacttttgg ggagactcta
    12601 aagaaatttg aacctctttt aaatatttgg atttagaaag tattctaatt aactcttcat
    12661 ttctaaatag tttttgacca ttagttgaaa atgagtatga aattctcaat ttttctagtt
    12721 gaataataat atattcaaag tactcacatt ctgtcggttc accgcccaat agagaaacat
    12781 gggtaaattc tttatcttgt ataatatcta ggacctgatt tatttcatca agctccaact
    12841 cttttccttg ataatcttcc aaataacaaa atttacacct taaattacat ttgttggtaa
    12901 gcatccaagt caggaacagt ggatttttta ggtaattaat catcttactt ctccaatcta
    12961 taaaaaaata cagataattt ttattatctg tatcttaaca tataaaattg ggtggaaatt
    13021 ttcttttgga atatatgcca aagccctata atttttcaat ttcttcaaaa aggacctttg
    13081 cttctagtgg gaaaccataa tctgcaagag tttgcgcgtg ttttttcatt tcttctatcg
    13141 ctccgttttg tttttgcaat accttataat gagctttgtg atattcaaag agaatttttt
    13201 catagaaaaa attgatacct attcctattt cttttaaatg gttaatgtat ttaaaagctt
    13261 gcattaagtt ttctcgacgt aaccaagtat caatgagatt taaaaatgtt cttattacga
    13321 tctgttgatt gagatgaatg gaatgataat aatttgattt tcctaaaatt tgcattccgt
    13381 aatactttag tgcattatca tcaaaatgtc gaagacaatt gccaaaaacc cacagttcat
    13441 agcgtcccca ttcgctgaca gattcaaggt agttcatcaa aaggtcagta tcttccttaa
    13501 aaacagtaga accttttgcc attgctaagt tgattttaac cactatttta ttaatctgat
    13561 aaaatttatt atcaggtttc tgttggcatt tttcttccca aaaattttga atttccttta
    13621 ttactttgat atttttttgc gcataagcca cagccaactc gtgacggtag ttgtattcat
    13681 ctgattgttc atattcgtta taaaggtttt gaaattcatc taaatagaca tttgagtttt
    13741 ctaaaacggt aaatagttta cccaccgtaa tctctgtttc tcctttttca aattttgcga
    13801 gctgagattc tgaaaaatcg ccaccagtca tttcttttaa tttcagatgc ttcgtttctc
    13861 tgataaaagc aattattatt ccggttttta aatttttttc catttcattt tccctttgtc
    13921 atatattcca aatttattaa attatttgaa attattatac aactttgctt ttagcttgta
    13981 aactagataa aaaaactact gacagctttt ctgtcagtag ttttttattt ttctaaaata
    14041 aatatttttt ctagctaaaa gataaattag gagaataagt aaggaaatca gaccaaatat
    14101 taaataaata aattctacag ttaaattttg ggcaattaga ccgcttgata aatcagcaaa
    14161 aataaaaaac agagataaaa atgtatcata tattgaccag aaaactactc gattattttt
    14221 tattagttta ttaaattccc caatgaaaaa gttattatag ccaccattta ttaatctaaa
    14281 aatagaaaat aaaacaatag tagtaaatac cgattttgta aaaaataaaa gaattgatat
    14341 taatggtaat agcataacta tcgataattt tttccacttt attcgactcc caattgccat
    14401 acatacatta aaagtaaaca aaacaagccc taaatactta agtggaaaat aatgatattt
    14461 caataaaata ctactccaac tattgacaga catgatgagt gttgtgacag ttattcctaa
    14521 taaaatgaat aagtttagct tagacgatac ttttaatccc tttcgtaatg tccttatatt
    14581 aatagttatt ttttcttctt gtttttcttc tcttttttct aattttataa aacataaaaa
    14641 aatggttgaa aaaacaataa atgctactga tattatgatt ggtaaaaaac gattgaaatg
    14701 tagtatggct ggtgtgataa ttgtcatcac tgatattgca agatattgta ttgaactgct
    14761 gccttcaaga tatttgcgat atgtaacatc atctggaaat tgttcataag aaaaagtttg
    14821 cattactcca gaagatagag cttctgatat cccaagtatg accgctgcta agattgctaa
    14881 ataaaatttt tcaaataaaa atagggtaaa agcaataatt gacaaaatat tattaagtaa
    14941 taatactttt tttctatttt tttgttcagc ataaatacct agcggtagat ttaaaatcac
    15001 tcctattatt tgcgtcattg cactaataat cataatctca gaatatctat aacccaaagc
    15061 attcataatt aatatgctaa taaaaaaata gggaaggagg gacaaaaaga gtttaaatag
    15121 aaaaagttgt ttatatttga ttatgatttt catagctgac aagttttatc tttcgtaaag
    15181 ttaggattta atgttctttg taatttggga tagcatcccc cctcgcaaat tcttaacatt
    15241 gagcacttta aacaatcttt attttctgtt ttaaattctc taacttctgt ataatttgaa
    15301 tcgtttttcc atatttcagc caatgtttga tgaaaagcat tggaagtatg cttttcacct
    15361 aaaaatgcaa tacaaggtaa gacatccccg ttagataaaa tctccttttt cgtatgcttc
    15421 gctctacaac caaaatacat attttcaaat tccgatagat tttttccctc ctcaattaac
    15481 tctggaaaag ccgtaaaata aaaacatcct tcaactgaaa aattgaaatt atctatttta
    15541 ttatctagta gatatcttct aactttttct tctaattttc tcaggtctga tatattgtat
    15601 atttttgtta tttttgtaaa accagtcact tcggagtagt ccgcaataga aaaacggtca
    15661 atttcgtttt taatcgcaaa cttcaagagc tccataatat cctcttcact ttgattagaa
    15721 taaaccgtat ttaatctgac tttctttttt ctttcatgaa aaagctttat taattctatt
    15781 cctctttttg cccttgtacc catgagttca aaatttttaa aatcatctat tgattcaaga
    15841 gatataactg gggtaatata atcagattgg caaataatat ctattgttga tttttttatc
    15901 tcttgaccat ttgttgttat tgttgtcact actttcaatg aatcaataat ttttaaaaga
    15961 ttatctatgt ctttatattt cgttggctcc ccacctaata tagaaaatga taaaattcca
    16021 ttttcttttg cttgacttaa aatctttttc caatcatctg caagatgaac attttcgtct
    16081 tctctgtttg caagaaagca aaagccacaa tgaagattgc aatacatact aggataaatc
    16141 actaactcta gcggaaaact catttgattt aattttttca gctctttaat cttactttgt
    16201 attttattaa taattgagaa agaagatacc tctttttctt ctatctctcc ttttttataa
    16261 attttttctc gtaaaatttt tgttagagaa tcagcattaa aatattttat gtattcgtta
    16321 aatgcttttt cttttcccat ttcttttact aaagataaaa aaatagactc actttctgac
    16381 aattacattt ttaagcattg ccaaaagctc tggtttggtt gattgttctt taagttcttt
    16441 ttgcataata aatctccttt taatatagac agataccaat tttgattcaa ttggtatctg
    16501 ttattttatc aaaattattg atagtataaa ttttatttgg aatatatgcc aaaactctat
    16561 taattgttaa gttcatgaga aaacccacgt tgttactata ttggctctct ttttttcttc
    16621 tttattttta ttactctatc tccagttttt actttcaaaa ccccaattct aaacttttta
    16681 taaaaaaatt tattttattt atcttttgtc atatattcca aaaatatccg atgaaaaaac
    16741 tactgacaga aaagctgtca gtagttttta tttttctaaa taatctaaag cgtcctgaat
    16801 agttttgacg ggaacgattt tcatcttcgt ttttagtttt ttagctgcgg ctttggctcc
    16861 aaggtaattg ttgctacttt cctttttggt gcctgagtca ggcactaaga agacctttgc
    16921 cccttctttg ctcgctgtgg ctactttttt atcaacaccg ccgatttgac caatgcttcc
    16981 gtcgtgttca atcgttccag ttccagcaat ttcgcgaccg tttcgcaaat cttttcctgt
    17041 caactgactg taaatttcta gtgtaaacat catccccgca gagggaccac cgattgaacc
    17101 cgcgttgaca gtaacttttg gagtcgtcac gacttcagta tggtcaacta ggctgatccc
    17161 aattcctgtt tttccattag caattttgat gtatttgcca gttgacttgt gctttgtgcc
    17221 gtcaattctc gtgtattcaa tcgttactga atcaccgact ttttgtttgg aaacataagc
    17281 aatcatgtcg gcacttgatg taaactgttg accattgact gctgtaatcg tatctgcaag
    17341 ttctagctta tttttaaagg tcgaattttt ggcaatatca aggacataaa cgccttcata
    17401 tttaagttca taaggtttat tagctaattt aaaagcttga taaatcgctg tattctgtgc
    17461 cgtttccatg taaaactggt tgacacggtt gaactgtgcg tcgttaagtc caccagtcat
    17521 ttcttgctca ctgtaaatgc ttgtaaaact attaaaatgg ctgtaaatca ttgtagcaag
    17581 atttgctcgt gcaatttgga cagtcgtcag gaaaaaatca cctttatgtt catctttttt
    17641 gccttcaact ttgaccattt tccctaaagg ctcggttgtt ccgggcattt ccacatagta
    17701 acttgttgga taaaataaag ctaaaagggc aacaacaatt agaccaatcg agattcccca
    17761 ttttaatttg ggattaattt ttttattttt tttcatctaa tttccttaat tcacgactca
    17821 cattttctgg aacccaagca ctgacatctt gaccaaaggc atgtaattct cgcatccgtg
    17881 tggaatttaa tggttcaagt tctggttttg ctaagaaaaa gatggtttca atgcctgtca
    17941 tctccatatt aaaatagaac atattttttt catattctaa atcttggcta ttacgcaaag
    18001 aacgaaccag agctgtcacg ccaagttttt ttgcgatatt cactgtcaaa tcacgttcat
    18061 gtttgatgac tttgacttta tgagtgactg acagacttgt cagtgcttct tctagcattt
    18121 ccactcgttt atcagttgga aaaagtggat ttttttggtc atttttaaaa attccaacat
    18181 aaagttgatc aaaatgttga ctggcacgtt tgataacgtc taaatgacca tttgtcagtg
    18241 ggtcaaaagt tcctgtaaag agtccaattt tttctgtcat tacttttttc tttcttaatt
    18301 tactgacaga atttctgtca gtaaaagtca aaattcataa attgaaattt tagaaattcc
    18361 gtaagttttt tgtctggtca gctctaattt cccaatttgg ttagggagtt caacttcctt
    18421 gtctgtttca cagacgacaa ttacattttc tgtcagtcgt tttttgtctt gcaaaagttc
    18481 taagttttca acaatttgtt ctttagcata aggtgggtct aagaggacta aatcaaaagt
    18541 ctctgacacg tttgataaga ctcgttctgc tgacattttt aataattgaa atttttcagg
    18601 ctctttggtc atcttgatat tttccaaaat gacttgttga gctgctctgt ctttttcgac
    18661 aagaatggcg tgatccattc ctcttgaaat ggcttcaatt gccaaactac ctgagcctgc
    18721 aaataaatca agaacacgtc ccccttcaaa ataagggcca atcatattaa aaatggctcc
    18781 tttaacttta tcggtggttg gtcttgttgt ttttcctgcc aatgttttca gcggtcttcc
    18841 gccataattt cctgaaacta ctctcatgaa aataattata tcacaaaatt tcaaatggag
    18901 agccgaatct ccctgtaagc cttggtttaa aggttctgtc agtaaaaatt ttcttattat
    18961 tttactgaca aaaaaataag tttctcaaat cagaatttca ttctaacttt tgaaacttat
    19021 ttttacctat atttaactca tgaatgactt tcatgcatcc gaattgctcg tagtgagggc
    19081 agcacaccta atacaataat gaaaaacatg aagatggtca ttccaatatt tccataaaga
    19141 cttgagagag agacaaggat tcctgacaag accgaagcga taggctgagt cactgaaaaa
    19201 gctcctgtat aagttcccac ttggtctccg tccattaaat cggcccgcag agcctgtgaa
    19261 aatggaacca aaatcatttc accgattgtt gctatcaatg ctgcaatcag ttcccaagtt
    19321 aaatcacgac caagaaatgc aatcatgaag cccaaacctt gcaaaataat tccaatggat
    19381 attccactac ttcgtgacca gtttttggtt agtttgttga ctctccccat aaataatacg
    19441 atgactaagg tattgaccat taggaaaatt gtcagcatcc gttgtccata aacttcaatt
    19501 ccaaaaatcc ttgctgttct aaaactatca ctcaaatgga ctggaagata ataatcaatt
    19561 tgattaaaaa tcatcgcaat aaagaccgaa gcaaataaat aatacatgaa aatacggtct
    19621 ttagcaactg tgaaataggc tttaataatg tttgattctt gcttatgctg ctgagtatct
    19681 ggattgaagg attcatcaat ccaaaaaatt acaaccaaac aactaacgat ttcttcaatt
    19741 gtgatagcta aaagtaacca aaccaaataa tctcggaaaa accaacctga aagtcccgaa
    19801 ccaatcatga ttgcaaagtt aataatccaa tattgaatac tataaacaac tcgccgattt
    19861 tcacttgttg tcaaatctac aatcatcgct tgacttgcgg tgttaaaaaa gccaaaacca
    19921 aaattaataa taagaaatcc taaaaaagta acccaaggat tgaagtaaaa agatgagttt
    19981 gcaaatgttg ctaaagctcc accaaaacca gtaatggcag ttgaaaaaat catcacaggt
    20041 cttcgtccct gaacgtcgga caaatgacca gcataaagcc caaccaagaa aaccatgact
    20101 gaactaatga ctaaaagtaa tcccgtgatt cccgctccca tatatttatt gtagtaaatt
    20161 gtcattgagc cacccactgt actaaagcaa agcgtcccaa aaaaattcat gattaaacga
    20221 attttaagtg ttggatgtaa tccaaaaaaa tctttcattt tatttctttc tgtttttttt
    20281 caataaaaaa tctatcttga ctccttttca agataaattc ctgtttttag aagtcatttt
    20341 tttaattaat ttttgttttc tggtgtctat ttacagcaat aagcactaaa ataatcgcta
    20401 gaacttcagt caatgctaag actaaagaaa ctcctgttgc tttaatcatt ggtgaaatcg
    20461 aaacaagtaa accggcaaga atggaggcaa tcggcatctt aattgcggca acgccattgt
    20521 aagaaccaat tttttctgga ttcatcaaat ctgcacctaa agtttgaaca cttggtgtat
    20581 aaacaatttc acctaaagta taaacaatac cggcaatgaa aataggagta aacgtcgttg
    20641 tcaaaaatga aaaaatcatc ccaattgcca taaataaact cccccaaata aatccttttt
    20701 ggtgtgacca gtccttggtc aatcgattta gggtggtcat taataggacc actaaaacac
    20761 aagctaaaat caaataaatc gtaagcatcc gttgtccata gatttcaaaa cccaaaaaag
    20821 tgattgtttt aaaactattt gataaatgaa caggcaaaaa attatcaaat tgcatgataa
    20881 taaaagtagt cgcaatatta gcacccataa aaatcatata agttttgtct tgtagcactg
    20941 tcttataggc ctgaaaaata ttttctgctt cctctttggt ctttacaatc ggtctaaaag
    21001 tctcagtcat tacaaaagtg gttaagaaaa atgagactaa gacagttaaa agtaatatca
    21061 ctaaaagtgc ttcaaatgct ggtctaaaaa gccaagcacc taatgctgct cctaaaataa
    21121 ctgacaagtt ttgcgcccaa taatctaaca taaaaacaac tttacgattt tcagcattcg
    21181 atgcatcaat aatcatggca tttcctgcag taatcacaag attataacca aaactaatca
    21241 gcaaaaaagc aataaaagtc gaccaaggat tcacgtgacc aggtaagttt gagccaatag
    21301 ctaaaagagc tcccaaaagt tgaatcactg tcccaaaaac catcactggt tttcgaccat
    21361 ttcggtcagc aaaaaaacct gcaagaattc ctgcgacaaa agtggctact gcagataagg
    21421 caagcaaaat ccctgtaatt gcacttccca aatgttgatt ataataaatg gtcattgaag
    21481 aaaaaacggt gccatatgaa aaggcaccta aaaaaacaat tcctaaacgg agttgcaaat
    21541 ttttgtctaa attccaaaac tctttcatat tattccttaa attcttttaa attttctaaa
    21601 tttattaatt tatctataat tgtagcatat ttatacttct aaaactagat gaattacagc
    21661 tttatcaaaa taattcttct acttatatca atttttgtta aaataaactg taaccaaact
    21721 taatttgatt tgttatatat ataagagggg aggaaatggt gaatttaaaa gaatatgaaa
    21781 atgacgtcaa tgattatgcg atagaaatca ctaaatacct tatctctcgt ggaagtcagt
    21841 tggtcgatgc cgaagatgcc gtacaggata ctctggttaa aattttaagt ctggatattt
    21901 tcattgaacc tgacaaatta cgggctttta tgtatcgaac atctatccga acttatatta
    21961 atagttataa tcggagtaaa cattatcaaa aaattattaa aaatttggaa aaagaattgg
    22021 aaacagcagc ttttttagtt gagtctagcc cacttccaaa aatcattgaa caactttccc
    22081 cttattataa agagctttta aatgcatact attatgaaaa ttgttcaact aaacagcttg
    22141 cagaatattt tgaatgtagt ttaagtaaaa tcaaaatcga cctttatcga gctcgaaaaa
    22201 agcttaaaaa acaacttgaa aaagctggtt atgaccagtg gctcctctaa tcgtctcatg
    22261 aaaggattta aaaatgcgta ctctcttaat tttcccttac tttgtcttag ctctcacttt
    22321 atttttcgga ctgattcgtc tgtttatttt tgcgatcaat aaaacacggc acaaacttca
    22381 aacaactgaa tctatttcta atctcaacaa agattttcat aattttgccc taaaaacaaa
    22441 aataaaacgt tgggggttaa ctacttggat tgctttgact gtattttcag cgtttatagt
    22501 tgttggttgg cgagtgaact ctgctatcat ggaaaaaaat ttctttaaaa cttttgatta
    22561 ctctaccgct attttcaccg cttccgcccc aaatgttgct tataataatc agattatcga
    22621 tgattatggc gtgtttagtt ctaatcttca ttcagatact tataaagata ttgatggtta
    22681 tcatgtgccc tgggaatctt ataatttttc ctttaatgtt tcgaatgttg ggggcttaag
    22741 tcttaatacc ttgagtccgt cagtaaattc aaatgcctat tttacccaaa caactaatca
    22801 aaaaattgct agttttttct ctacaaatgc caactacaaa tctaaagatt ataatggaat
    22861 tctgcctacc catgatgcag acaaaatttc acaactttca aaccacgtgg cggaagttgc
    22921 tgtcaccttt gataaagctt atagttacaa cgaaatccaa aaaatgattc ccgaaaatct
    22981 tttaattaat tggtattgga ttggttacaa tgattcgaaa tctcttgatg ctgctggaca
    23041 aacaaactgg tttggcttga tgagtaatag caattatgct gaaaatggta ataattcaca
    23101 gctcactgga aaattagaca atactactta tcaagatttt aaaaagtcag tagctgctat
    23161 tgcgaaaaag aaccaaatca caattaacga ctttagccca agtaaagatg cacttaaaca
    23221 agttaaaaaa tatcctactc ttaaatcagc taaattttcg ggggtcattt taacaggaca
    23281 aactaagaat tttgtgaatt ttgataaaaa ttcttgggtt tatgcaagta atgtcgggct
    23341 tacagtagaa cttcgccctg atattaagcc acttaaataa taattttact gacaggattt
    23401 gtcagtaaga aatggataca aaaaatcact gacagaaatc ttgtcagtga tttttatgac
    23461 acttttaatc aaagattaaa ggcggtcatt caattctttg ctgagttctt caaatcctgg
    23521 tttaccaaga agagcgaaca tatttttctt gtaagcttca acacctggtt ggttgaatgg
    23581 gttaattccg ttcaagtaac cagaaacacc gatagcaagt tcaaagaagt aaattgcata
    23641 tccaagtgtg aattcatctt gttcaggcaa tgtcacgatc atgtttggaa catttccgtc
    23701 agtgtgagca agaagcacgc cgtcagctgc ttttttgtta acgaagtcaa catctttacc
    23761 ttgcaagtat ccaagtccat caaggtcagc gtcaagttct ggaatgttga tgtttttacg
    23821 tggtttttca atacggattg ctgtttcaaa aacagtacgt gttccttctt gaatccattg
    23881 tcctaatgag tgaaggtctg ttgagaagtt agctgaagtt gggtaaattc ctttttggtc
    23941 tttcccttct gattcaccag ccaattgttt ccaccattct gagaaatatt gaaggcttgg
    24001 ttcgtaattg atcaagattt ctgagaactt acctttacgg taaaggatat tgcgaagtgc
    24061 agcataggcg taagcatcat tttcatgaac atttgtagaa gtgtattctt tacgcgcagc
    24121 gttagcacct tccatcaaag ctgtaatatc agcacctgaa gctgcaattg gcaaaagtcc
    24181 aacagctgtc aatactgaga agcgtccacc aactgaatct ggaacaacga aagtttccca
    24241 gttgtttgcg tcagcattaa cttttacagc acctttttct ttatcagtgg ttgcgtaaat
    24301 acgtttgttt gcttcttcac gaccgtattt tttaactaac atttcttcga agacacggaa
    24361 agcaatcgct ggttctgttg ttgtacctga tttagagatt acatttacag agaaatcttt
    24421 gtcagcaacg taatctacaa ggtcagccaa gtatgatgaa gaaattgagt taccagcata
    24481 aagaatacgt ggtgctttac gttcttcggc agtttgcaag ttaacaaagc tgttgctcaa
    24541 aaagtcaatt gctgcacgtg caccgaggta tgaaccaccg ataccgataa caataagaac
    24601 ttctgaatca gattgaattt ttttagctgc tttttgaata cgagcaaatt cttctttgtc
    24661 gtaatcttca ggaaggtcaa gccatccgat ataatcgctc ccagcacctt ttccttcgtg
    24721 gagcaattta gctgccccgt cgatttgcca ttggatttcg tctaattcat tttcagctac
    24781 aaatggagtg agttttgaat agtcaaattt aatatgagcc attttaattc ctttcaattt
    24841 ctcgtttttt acgagaattt agctattgaa gaacgacaac ttttgcattg ttttatcttc
    24901 gaattttcta gttcatttta tcactttttc ggctttttaa caatactaaa ggttatgtaa
    24961 gcgcttattt gtttagcttt ctatctctga aacttttcca gctttgagac agcttttttt
    25021 atcaaaactt agtttaagat ttcaatgaat atttattgtc atcaaaaaat ttactgataa
    25081 gataagtcct aacacttttg agggtgtcaa atctctttga cgactgacaa atcagtcttt
    25141 catgtaaatt tttgctaaaa tattaatgat gaaatataca tttgaaattg accttgaccg
    25201 ttataaaaat ctggcccaac aaaaacaaaa gacacataag aaatttttag ctggacttgc
    25261 caaaaaacca ccaaagcaat tagataaaat cgttaaagaa gttcatgaag aggttttttt
    25321 agaaattgat tgcaccaaat gtgctaattg ttgcaaaacc ttaggccctc tttggacaga
    25381 ggccgatatt gaacgcgtcg ccaaacattt aaaaatgaaa gtgagtgact ttgaagccgc
    25441 atatctccga actgacgaag atggtgacaa agtttttcaa accatgcctt gtccgtttct
    25501 tggttctgac aatctctgta gcatttacga agttcgtcct aaagcttgtc gcgaatttcc
    25561 ccatactgac cgtaaaaaga tttatcaaat caataattta acgataaaaa atacacttta
    25621 ttgtccagct gcttatgaat ttgttgagaa attatcttat agactcaaat aaaaattact
    25681 gacaggtctg tcagtaattt ttttattatg ccaaaagttc tttcaaagct tcttttgtat
    25741 ctgtcagtga atgtcccaag gctttttcaa aatctttaga ttccacatct aaatcttttg
    25801 cttcaatatc tttttggaag ccgaggaaaa gttccgctac aaaatctgga agtccagttt
    25861 caactaaatg actgacaaaa gctttgtcat cagcagcgac tacttcaaat tccttatcag
    25921 aaactgcttt tagtgcttga gcaagttcgg cgtaagtcaa tatttttcct gaaagctcca
    25981 aaacttctgg aaaatctgct ccagcaagtg cttttgctcc aacttctgca tattcgcgtt
    26041 tcaaagccca gcccacttta cctgttggtg cattgtaaac aaattttcca attgaaagtg
    26101 cagcagcaat aattggcatt tcattttcaa agtaccagtt attacgtaaa aatgtgtggg
    26161 caattcctga tttttcaatc gccttttcag tatagatgtg gtcagcagct aagtcacttg
    26221 ttgccctttc tgcttgagga aaacttgtat aagcaatata agaaattcca gcacttttgg
    26281 ctgcatcaac cacattttga tgctcagctt gacgatttcc cggcgctcct gaaacaaaaa
    26341 gcaaacggtc aattcctgta aatgcttgtt ctaaagcagt ta
//
