LOCUS       NZ_MTJR01000006        20858 bp    DNA     linear   CON 23-AUG-2024
DEFINITION  Lactococcus lactis strain 417 contig_12, whole genome shotgun
            sequence.
ACCESSION   NZ_MTJR01000006
VERSION     NZ_MTJR01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactococcus lactis
  ORGANISM  Lactococcus lactis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 925578)
  AUTHORS   Ho,V., Lo,R., Bansal,N. and Turner,M.S.
  TITLE     Characterization of Lactococcus lactis isolates from herbs, fruits
            and vegetables for use as biopreservatives against Listeria
            monocytogenes in cheese
  JOURNAL   Food Control (2017) In press
REFERENCE   2  (bases 1 to 925578)
  AUTHORS   Lo,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2017) School of Agriculture and Food Sciences, The
            University of Queensland, Hartley Teakle Bldg (No. 83), Slip Rd, St
            Lucia, Brisbane, QLD 4072, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. Jun 2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 793.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563455.1-RS_2024_08_23
            Annotation Date                   :: 08/23/2024 15:24:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,353
            CDSs (total)                      :: 2,288
            Genes (coding)                    :: 2,273
            CDSs (with protein)               :: 2,273
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 15
            CDSs (without protein)            :: 15
            Pseudo Genes (ambiguous residues) :: 0 of 15
            Pseudo Genes (frameshifted)       :: 5 of 15
            Pseudo Genes (incomplete)         :: 10 of 15
            Pseudo Genes (internal stop)      :: 4 of 15
            Pseudo Genes (multiple problems)  :: 3 of 15
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:59:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 167811
            Orig. end                         :: 188669
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            MTJR01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20858
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20858
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20858
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10858](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10858
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(29..2116)
                     /locus_tag="BW153_RS04120"
                     /old_locus_tag="BW153_04110"
     CDS             complement(29..2116)
                     /EC_number="7.2.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015662 - P-type ion transporter activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010905590.1"
                     /locus_tag="BW153_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04110"
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="WP_098396458.1"
                     /transl_table=11
                     /translation="MSNKTHSSNHDEMMSEHHHNHEMMDMEHENHEMHNMHNMDNMHDM
                     DNMDMMNHGGHMMHMGDMSKKLKVAIILMIPLLLISPIAGFTILKFPGSEILQLILGTI
                     IFFYSGTPFFSGAKGELKSRKPAMMMLITMGITVAYAYSVYATIMSLNGHMGMNFWFEL
                     ATLIVIMLIGHLIEMKAIMGAGDALKDLASLVPKKAHLKSGKDVELSELKVGDLLLVKE
                     NEKIPADGLILSEALVDESMITGESRAVNKKTNDLVYGGSLNQNQPFEMKVTTLGKDSF
                     LNQVAELVKKAQAQKSNLENMADRVAGYLFYAALIVGIFSLVFWTISSNFSFALLLAVS
                     VFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGK
                     FIVRNVIDFTDETDILQIMAALEGSSTHPIAQSIVSAAKPLENLKVEAVENIPGVGIKG
                     QVNQNFYQIVNYKYLRENQLSYDEQKIAQYLDLGLTVSFLINEQQEVLGFIALGDSPKA
                     DAKAFINGLLAQGITPVMLTGDNKETAQKIASALNIPEFRAELKPEDKAEIVKEYQKKA
                     GVLFIGDGVNDSPALATATIGFAIGAGTSVAISTADVVLVNSNPSDVLDMINISKRMLR
                     KMKQNLWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDK
                     K"
     misc_feature    complement(2161..2176)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: strong, score: 30.52"
                     /tool="antismash"
     misc_feature    complement(2253..2269)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.66"
                     /tool="antismash"
     gene            2318..5941
                     /locus_tag="BW153_RS04125"
                     /old_locus_tag="BW153_04115"
     CDS             2318..5941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426153.1"
                     /locus_tag="BW153_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04115"
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="WP_098396464.1"
                     /transl_table=11
                     /translation="MIKIRPEVTTVTSKSHFRTWKSGKSWLFATSALAIIIVSGTITDQ
                     NVKADTAVDSSQQISGITEVTSYSALASSTNSDVAASQNQVAYEQASDQSSNKSLANTV
                     ETDTEGITSNVSDSSNSINESQNTTSTAVIQTPTNNIVSLADSSSSNDNGSNSILSSSN
                     AADSVDSAAVSQSSTSSSVILSESSAIDSGIGSTSQSSAIDSGIGSTSQSSEMNLAGNS
                     STNASSAAVASFTAILATNSSMVLPILTQALATTAPATTSGSATLNTTLGDLVNQAIST
                     VGISGLENIFSTLGTFNIPGMTTAASALNGVEQIVNIVGNIQEAAANPGAFLLNGMKSA
                     GLDVSQIPLVGGQIAASFNAIPSMSPAAMLTFLENPTIPGLSSIPGASLVLSPVLSAIS
                     TVTSGIVNQHNTTTSNALGGVNFDLDTLVSLQGNDLVNYLAGLVVNSAINRVGQIAWSQ
                     LSPTISNIPLVGTTVNNVLSPILNNLTGASLGEVANLTGVSSLLDQVNNSLGNLASLGS
                     TALATIENTLQNSLNSLGKLPAGASNILNQVLDQLQNAINNIVVSATGIVNNLPGLGAI
                     ENGLSNTISQIQNNINNFVNNALNGITTIINSLTPSVGASTVNPNSSANSSQSSSSASS
                     SSSAASSSTSSSNVSSNTSSNSSEANTSSSTSNASSSSSSSEGSSASSSNSSEGSATSS
                     SSVDSSQSSSAGVNGSSSAGVNGSSSSSEGSSASSSNSSESSIASSSSVGSSQSSSTGV
                     SSSSSSAEGSSASSSNSSESSIASSSSVDSSQSSSTGVSSSSSSAEGSSASSSNSSESS
                     VASSSSVDSSQSSSAGVNSSSSSAEGSSASSSNSSESSVASSSSVDSSQSSSAGVNGSS
                     SSSESSSASSSNSSEGSVASSSSVDSSQSSSAGVNSSNSSSESSSTSSSNSSEGSVTSS
                     SSVDSSQTSSAGSNSSNSNSEGSSASSPNSSESSIASSSLVDSSQSSSAGVNGSSSNSE
                     GSSASSSNSSEGNIASSSSVDSSQSSSAGVNGSSSSSKGSSASSPNSSESSMTSSGGTS
                     DSNSNNGQTSTTSSSSENSSHSSLSSNESSSASLTSSESSGSTTSSSMLTNPNLQSNDK
                     NGSSLTSNSSYTSEMKLNNLSDSNLPSNEAKVSTLISKVSSSPSLSNSLSATILQLVPT
                     VTKEELPKTGADDDLSLVLAELGLGLVATLTIGKVKYKKRF"
     misc_feature    2348..2363
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.48"
                     /tool="antismash"
     gene            6101..6955
                     /locus_tag="BW153_RS04130"
                     /old_locus_tag="BW153_04120"
     CDS             6101..6955
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131344.1"
                     /locus_tag="BW153_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04120"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_003131344.1"
                     /transl_table=11
                     /translation="MNLIDGKALAAKMQAELKVKVDKLKEADNVPGLAVILVGEDPASQ
                     IYVRNKARQATAIGLNSSVVRLPETVSEQELLDLIEQYNQSEQWHGILVQLPLPEHISE
                     EKVLLAIDPEKDVDGFHPMNMGRLWSGNPLMIPSTPAGIMEMFREYDVELSGKRAVVIG
                     RSNIVGKPMAQLLMMADATVTIAHSKTENLRELTKEADVLVVAIGRDRMIKAEDVKEGA
                     VVIDVGMNRDEDGKLHGDVDFDEVKDVASLITPVPGGVGPMTITMLMEQTVRAASRKMN
                     ENK"
     gene            7122..8375
                     /gene="xseA"
                     /locus_tag="BW153_RS04135"
                     /old_locus_tag="BW153_04125"
     CDS             7122..8375
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131345.1"
                     /locus_tag="BW153_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04125"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_058223413.1"
                     /transl_table=11
                     /translation="MTEYLSVSTLTKYLKAKFDRDPYLERVYLTGEISNFRRRPNHQYF
                     ALKDEGAVIQATMWAGQFRKLDFELEEGMKVLAVGRISIYPPSGSYSINIESLVPDGVG
                     ALAVKFEQLKKKLTAEGLFEQRWKQTLPQFSKKIAVVTSPSGAVIRDIITTVQRRFPMS
                     QIVLYPTKVQGQGSAEEIAGNIRRANQRGDFDVMIIGRGGGSIEDLWGFNEEIVVRAIF
                     ESRIPIISSVGHETDVTLADFVADSRAATPTAAAELATPNTKVDLINWANEQEKRLFNR
                     LTHLIKIRRERVDKLSQSIVFRQPERLYDGHLQKLDRLCERLAVLTENKVANMKHRYEL
                     SAGKLIPTYGKIVEAKKNKTEQLYQSLLLLDISKIKARGFSLVTDEKGKIIKSVSDVKK
                     GQTLDVELTDGKVIVEVK"
     gene            8375..8614
                     /locus_tag="BW153_RS04140"
                     /old_locus_tag="BW153_04130"
     CDS             8375..8614
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131346.1"
                     /locus_tag="BW153_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04130"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_003131346.1"
                     /transl_table=11
                     /translation="MATKKEDVKFEDNLAELENIVRKLESGDVALEDAIAEFQKGMKIS
                     ETLKKTLNEAEETLVKIVGKNDQESDFSPEQKDY"
     gene            8763..9920
                     /locus_tag="BW153_RS04145"
                     /old_locus_tag="BW153_04135"
     CDS             8763..9920
                     /EC_number="2.7.1.31"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864361.1"
                     /locus_tag="BW153_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04135"
                     /product="glycerate kinase"
                     /protein_id="WP_058223414.1"
                     /transl_table=11
                     /translation="MKKKFVLAPDSFKESLSALEVCQAMEKGIKKVFPKAEIISMPMAD
                     GGEGTTDALIDATGGRRVYKKVQGSFANTNVEAYFGILGNSNTAVIEMAKANGLELVAL
                     EDRNPLITSTYGTGQLIKAAMDEGVDKIIIGIGGSATNDGGSGMARALGARFLNKDQEE
                     IPLGGAFLKEVRTIDMSDFDPRVDEIEILIATDVTNPLTGNNGASYVFGPQKGATEEMV
                     KILDENLKHYAEIVHNDLGINVKNKPGSGAAGGLGAGLLAFTNAKMQLGIELVAQTIYL
                     EDKIKETDYVFTGEGGMDYQTKFGKAPYGVCKIAKKYKKPCFALAGYIGDGADVLYEEG
                     MTAIFGILSQAQSLSDALADGAKNVERTSENITRVLAMNEQKAHL"
     gene            10001..10858
                     /locus_tag="BW153_RS04150"
                     /old_locus_tag="BW153_04140"
     CDS             10001..10858
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012897509.1"
                     /locus_tag="BW153_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04140"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_021722025.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-53, bitscore:
                     177.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKILKLEDFLTEFYESAEFPTGLAESAKYSLLAGGKRIRPLLF
                     LNLLEAFDLELSKAHYHVAAALEMIHTGSLIHDDLPAMDNDDYRRGQLTNHKKFDEATA
                     ILAGDTLFFDPFFILSTADLSAEIIVALTRELAFASGSYGMVAGQILDMAGEGKELTLA
                     EIEQIHRLKTGRLLTFPFVAAGIVAQKSTDEVEKLRQVGQILGLAFQIRDDILDVTATF
                     AELGKTPGKDILEEKSTYVAHLGLEGAKKSLTENLSEVKKLLTDLSVTDSSEIFKIIEQ
                     LEVK"
     misc_feature    10912..10925
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.74"
                     /tool="antismash"
     gene            10938..11744
                     /locus_tag="BW153_RS04155"
                     /old_locus_tag="BW153_04145"
     CDS             10938..11744
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131349.1"
                     /locus_tag="BW153_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04145"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_015426159.1"
                     /transl_table=11
                     /translation="MKERIDVLATNQGLFETREQAKRGVMAGLVVDSKSGERYDKPGQK
                     IDDGTELRLKGEKLRYVSRGGLKLEKALKEFHLEINGKTCLDIGSSTGGFTDVMLQNGA
                     KLVYALDVGTNQLAWKIRSDERVVVMEQFNFRNAVLADFEQGRPSFTSIDVSFISLDLI
                     LPPLYEILEENGEVAALIKPQFEAGREQVGKNGIIRDPKVHQMTIEKVLKTATQLGFSV
                     KGLTFSPIKGGAGNVEFLVHLLKDGKAEIAQQVNIESVLQKESEEL"
     gene            11741..12187
                     /locus_tag="BW153_RS04160"
                     /old_locus_tag="BW153_04150"
     CDS             11741..12187
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426160.1"
                     /locus_tag="BW153_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04150"
                     /product="arginine repressor"
                     /protein_id="WP_003131351.1"
                     /transl_table=11
                     /translation="MKREDRLNFIAQFIRENEIKTQEELVNTLLTHGIDVTQATVSRDI
                     KSLALIKVPAESGGYRYDLPKNKEVLQSSLHKALAFDAITGTKIKDNMLWILANPGTTS
                     LVKNYLLEEYSDDIFSIIIDDDSALVIFEMEEDAKNLYNLLTEF"
     gene            12335..14002
                     /gene="recN"
                     /locus_tag="BW153_RS04165"
                     /old_locus_tag="BW153_04155"
     CDS             12335..14002
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019292004.1"
                     /locus_tag="BW153_RS04165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04155"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_003131352.1"
                     /transl_table=11
                     /translation="MLQEISIKNFAIIEEIHLSFESGMTILTGETGAGKSIIIDAMSLL
                     LGGRASSDFVRHGANKAEIEGLFFFDKTPELKAVLLELGFEEVDSEIILRREIFANGRS
                     VCRINGQMVNLATLRQVGELLVDIHGQHDSQELMNPKSHLRLLDEFGDEAFDQIKNNYK
                     LKFENFKNLRQQLNLRQKNEQEFAQRIEILQFQAEEIEAAEINLEEDEQLVNRREKLNN
                     IKNIADSLSSAYLALDDEDNDYSSLNNIRTTMTELDKISNFDNDYQELADKTAESYYVL
                     EEVANQIQRIMSDLEFNPAELLQIEDRIMTLTTLKKKYGPELSDVMNYLEKVQLELSEL
                     TGSENDSENLENSVKVAQVQLIEASKKLNEARHKIAKEVEKDIKHELSELYMEKADFKV
                     SFEGAKFSANGNEHVEFFIQTNPGEGFKPLAKTASGGELSRLMLAIKSSFSRRENKTAI
                     VFDEVDTGVSGRVAQAIANKIYKIARHGQVLAISHLPQVVAIADRQFYIEKASTDDITT
                     STVRKLNAEERVNEIAKMLAGEDLTKEALAQAKRLLSK"
     gene            14726..15292
                     /locus_tag="BW153_RS04175"
                     /old_locus_tag="BW153_04165"
     CDS             14726..15292
                     /GO_process="GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011675826.1"
                     /locus_tag="BW153_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04165"
                     /product="TMEM175 family protein"
                     /protein_id="WP_058223417.1"
                     /transl_table=11
                     /translation="MSKTRLEAFTDAIIAIIMTVLVLELVRPDSDSLQSFIALLPHLGV
                     YFVSFFILAIYWVNHHHLFQSIKRINGKVLWINISFLFVLSLIPIFSNWVSIYPNSFIP
                     ELGYVIIFFFGNFIYLLLTRELLKINGHRKTSETTIRKNILSVVLNIVSILLGYFIAPV
                     IMLVGSALIFSMWVIPDKNIEKMFK"
     gene            15390..15911
                     /locus_tag="BW153_RS04180"
                     /old_locus_tag="BW153_04170"
     CDS             15390..15911
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015426163.1"
                     /locus_tag="BW153_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04170"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_003131354.1"
                     /transl_table=11
                     /translation="MIKAYIKYWKKAGDLKSYSNRSDYWWVFLTNSIIFAILSILNFMV
                     TIPKAGKIMSQSATLSQKEIIQQVTDLYANPTGGALVIVIVTALIGLAILVPNISLTAR
                     RLRDARFPWWIALVFGVAAIYGLVTMFIHQDLLAKMGYFVGFINFIIYILCLFPTKYGI
                     DEEDDSRTYE"
     gene            15934..16866
                     /locus_tag="BW153_RS04185"
                     /old_locus_tag="BW153_04175"
     CDS             15934..16866
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864363.1"
                     /locus_tag="BW153_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04175"
                     /product="DUF805 domain-containing protein"
                     /protein_id="WP_098396468.1"
                     /transl_table=11
                     /translation="MVQAYKKFWLGAFTFNKKTSRKDFWSALLTHIIIFVILFKAYHFF
                     NLLDFYQLTTLWQTFASFFQLIFNLYFFGSLLSFIALTVRRLNDADLPWGLIFLNFILG
                     LGTLVLLILNLFPSSPRALKFKEYEINSSQEFNNLPETKTLSGIFKDYFKNYFEFRGRT
                     TRRNFWWVQLFWGLTVILFLFLIYLFNQFEQIMFGYNFIGSMVLRLFFFLFILGTFFPQ
                     LTIHVRRLRDAGLSNLGLSLSLGGTSGILIFYQMFTKTLKITYTTGHYQLVQYLLFLLV
                     MIAVLSLILVEVMATGELKTNKKNSLFEK"
     misc_feature    complement(16994..17007)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.27"
                     /tool="antismash"
     gene            17091..18044
                     /gene="rsmH"
                     /locus_tag="BW153_RS04190"
                     /old_locus_tag="BW153_04180"
     CDS             17091..18044
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017864364.1"
                     /locus_tag="BW153_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04180"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_015426165.1"
                     /transl_table=11
                     /translation="MPKTIAFKHDTVLLHETVDMLEVKPNGIYVDATLGGAGHSEYLLS
                     KLTNGHLYSFDQDETAHENAKVRLSEQLAEDKVTLIKSNFRYLKSALAELGVTKIDGIL
                     YDLGVSSPQFDDSQRGFSYKKEARLDMRMDQNQTLSAYEVVNEYPYEALVRIFFRYGED
                     KFSKQIARKIEQARKIKPIETTIELADLIKSALPQKELKKKGHPAKRIFQAIRIEVNDE
                     LGAAEESIEQAIDLLKVDGRISVITFHSLEDRLTKTIFKEYSTVNVPKGLPMLPKDMEA
                     KLKLINRKPVLASEEELEFNNRAHSAKLRVAQKQRD"
     gene            18202..18582
                     /locus_tag="BW153_RS04195"
                     /old_locus_tag="BW153_04185"
     CDS             18202..18582
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003131357.1"
                     /locus_tag="BW153_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BW153_04185"
                     /product="cell division protein FtsL"
                     /protein_id="WP_003131357.1"
                     /transl_table=11
                     /translation="MAAQPKEYFDIETAAKKDSYLIDTETLAPEVLASKFKKFSGVEKV
                     FYLTMVVAALVLAVGLLYVKTKTLEVQGNTMDLRSKISQETTRKTEYDQQILDLTSGTK
                     VLDTANKADLKQNPSNVLKATK"
     misc_feature    19909..19923
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.12"
                     /tool="antismash"
     misc_feature    20482..20499
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
ORIGIN
        1 ataaaaaaat agaagagcat aggctcttct attttttatc atacctcaat cccatcgcgt
       61 tgattgagac aatcacggtt gagattgaca tcagaactgc tgcaatgaga gggtcaatat
      121 aaatccctgt aaatggataa agaatacccg ctgcaacagg aatagcaata atgttatagc
      181 ctgctccaaa ccagaggttt tgtttcattt ttctaagcat gcgtttggag atattaatca
      241 tatccaagac gtcacttgga ttggagttaa ctaggacgac atcagcggta ctgatagcaa
      301 ccgaagttcc tgctccaatc gcaaaaccaa tcgtagcagt tgcaagagct ggggaatcat
      361 tgacaccatc accaatgaaa agcacgccgg ctttcttttg gtactctttc acaatttctg
      421 ctttatcttc aggttttaat tccgctctaa attcgggaat atttagtgca ctagcaattt
      481 tttgagcagt ttctttatta tcacccgtga gcataacagg ggtaattcct tgggctaata
      541 aaccattaat aaaggctttc gcgtctgctt taggagaatc tcctaaggca ataaatccta
      601 aaacttcttg ttgttcattg attaggaaag atacagttaa acctaaatct aaatattgag
      661 caatcttttg ttcatcataa gaaagttgat tttcacgaag atatttatag ttaacaattt
      721 gataaaagtt ttggttaact tgccctttaa ttccaactcc tggaatattt tcaaccgctt
      781 caacttttag attttcaaga ggtttagcag ctgaaacgat tgattgagca atcgggtgag
      841 tggaacttcc ttcaagtgct gccatgattt ggagaatgtc tgtttcatca gtaaaatcaa
      901 taacattacg aacaataaac ttaccgtcag ttaatgttcc cgttttatcc attaaggcat
      961 atttaattgt atttattttt tctagagaag ttctgttttg aattaataaa ccatttttag
     1021 cagaaatact ggttaggcga gaaacaacaa gtggaaccgc aagacctaaa gcgtgtggac
     1081 atgcaattac aaaaacagaa accgcaagaa gtagagcaaa actaaagtta gaactaattg
     1141 tccaaaaaac taatgagaag ataccaacaa taagtgcggc atagaaaagg taaccagcca
     1201 ctctatctgc catattttcc aaattagatt tttgagcttg ggctttcttg actaattcgg
     1261 ccacttgatt gagaaatgaa tcttttccaa gggttgtgac tttcatctca aatggttggt
     1321 tttgattgag ggaaccacca taaacaaggt catttgtttt tttattgact gctcggcttt
     1381 caccagtaat cattgactca tcaacgagcg cttcacttaa tataaggcca tctgcaggta
     1441 ttttctcatt ttctttcact aaaagtaaat cgccaacttt tagttctgaa agctccacat
     1501 ccttcccact ttttaagtga gcttttttgg gaacaaggct tgctaaatct ttcaatgcat
     1561 cgccagcacc catgattgct ttcatctcaa tcaggtgacc aatcaacata atgacaatta
     1621 aagttgccag ttcaaaccag aagttcatgc ccatatgtcc gttaagactc atgattgtgg
     1681 cgtaaacaga ataagcatag gcaacggtaa ttcccattgt aatcagcatc atcatggctg
     1741 gcttacggct ttttaattca ccttttgctc cgctaaaaaa aggagtccca gagtaaaaga
     1801 agataattgt accaaggatg agttgcaaaa tttcacttcc ggggaattta aggatagtaa
     1861 agcccgcgat tggtgaaatg agtagaagcg gaatcataag aatgatagcc actttgagct
     1921 ttttactcat atcacccata tgcatcatgt gtcctccatg attcatcata tccatattgt
     1981 ccatatcatg catattatcc atattgtgca tgttgtgcat ctcatggttt tcgtgctcca
     2041 tatccatcat ttcatgatta tgatgatgct cagacatcat ttcatcgtga ttagacgaat
     2101 gagttttatt tgacatattt tcctcctaaa tgaatgcttt gaaatttcta tctatatata
     2161 gtttacaatt gtaaactatc aaagtcaagg aaaaaagttg tattctataa acgttacaaa
     2221 taaataaccg taaggtttct tttgtgacct aaatgtgata ttataatata tattcatagc
     2281 gatactcaat aaaaaagtat cggcaaggag agaataaatg ataaaaatac ggccagaagt
     2341 gactacggtt acctccaagt ctcattttcg aacttggaaa tcagggaaaa gttggttatt
     2401 tgctacttca gcattagcta taattatcgt ttcaggaacg attactgacc aaaatgtaaa
     2461 agcggacaca gcagttgaca gtagtcagca aattagtggt attactgagg taacaagtta
     2521 ttcagcacta gcttcatcga caaatagtga tgtagctgct agtcaaaatc aagttgctta
     2581 tgaacaagct agtgaccaaa gttctaataa gtcactggct aacacagtag aaactgatac
     2641 tgagggaata acttcaaatg tgtcagatag tagcaattca attaatgaaa gccaaaatac
     2701 gacaagtaca gcggttattc aaactcctac aaacaatatc gtatcgcttg cagattcaag
     2761 ctcatcaaat gataatggca gcaattctat attaagttct tctaatgctg cagacagcgt
     2821 tgattcggca gctgtctctc aaagttcaac aagttcatca gtaattttga gtgaaagttc
     2881 agcaattgat agtggtattg gatcaacttc tcaaagttca gcaattgata gtggtattgg
     2941 atcaacttct caaagttcgg aaatgaatct tgcgggaaat agtagtacta atgcttcaag
     3001 tgctgctgtc gcttctttta cggctattct agcgactaat tcgtctatgg tactaccaat
     3061 acttactcag gcactagcta caacagcgcc tgctacaaca agtggttcag ctactcttaa
     3121 cacaacactc ggagatcttg taaatcaagc aatttcgaca gtaggaatta gtggtttaga
     3181 aaatattttt agcacacttg gaacttttaa tattccagga atgactacag ccgcgtcagc
     3241 tcttaatggt gttgaacaaa tcgtcaatat tgttggaaat atccaggaag cagctgctaa
     3301 tcctggagcc tttctattaa atggaatgaa atctgcaggt ttagatgtta gccaaattcc
     3361 attagttgga gggcaaattg cggcgtcatt taatgctatc ccatcaatga gccctgctgc
     3421 tatgcttact tttcttgaaa atccaacaat tccaggactt tcaagtattc cgggggcaag
     3481 tctagtacta agcccagtac ttagcgcaat aagtactgta acaagtggga ttgttaatca
     3541 acataatacg acaacttcca atgccttggg tggtgttaat tttgatttag acacacttgt
     3601 ctctcttcaa ggaaatgatc ttgtcaacta cttggctggt ttagtagtta attcagcgat
     3661 taatcgagta ggtcaaattg cttggagtca attatctcca actattagta atattcctct
     3721 tgtaggtact acagttaata atgttttaag cccaatatta aataatctta ctggtgcatc
     3781 tttgggtgaa gttgcgaatt taacgggagt ttccagcctt cttgaccaag taaataatag
     3841 tttgggtaat cttgcaagcc ttggttcaac agccttagcc acgattgaga acacgctcca
     3901 aaatagtcta aactcacttg gtaagcttcc tgctggtgct tcgaatattc ttaaccaagt
     3961 gctcgatcag ttgcaaaatg ctatcaataa tattgttgta agtgcgacgg ggattgtaaa
     4021 taatttacca ggtcttggag ctatcgaaaa tggtctttcg aacactatta gtcaaataca
     4081 aaataatatt aataatttcg ttaataatgc acttaatgga ataacgacaa ttatcaattc
     4141 tttaactcca agtgttggtg cttcaacagt taatccaaat tctagtgcta atagtagcca
     4201 atcaagcagt agtgccagtt cttcatcaag tgcagctagt agttcaactt catcttcaaa
     4261 tgtatcaagc aacacgagtt ctaattctag tgaagcaaat acttcaagtt cgacttctaa
     4321 tgcttcaagt tcaagctcaa gctcagaggg ttcaagtgct tcaagttcaa attccagtga
     4381 aggtagtgcc acaagttcat cctcggtaga ctcaagtcaa tcgagttcag ccggggtaaa
     4441 tggctcaagt tcagctggag taaatggctc aagttcaagc tcagagggtt cgagtgcttc
     4501 aagttcaaat tccagcgaaa gtagtattgc cagttcatct tctgtgggct caagtcagtc
     4561 aagttctact ggggtaagta gctcaagttc aagcgcagaa ggttcaagtg cttcaagttc
     4621 aaattccagc gaaagtagta ttgccagttc atcttcggta gactcaagtc agtcaagttc
     4681 tactggggta agtagctcaa gttcaagcgc agaaggttca agtgcttcaa gttcaaattc
     4741 cagtgaaagt agtgttgcca gttcatcttc ggtagactcg agtcagtcaa gttcagctgg
     4801 ggtaaatagc tcaagttcaa gcgcagaagg ttcaagtgct tcaagttcaa attccagtga
     4861 aagtagtgtt gccagttcat cttcggtaga ctcgagtcag tcaagttcag ctggagtaaa
     4921 tggctcaagt tcaagctcag agagttcaag tgcttcaagt tcaaattcca gtgaaggtag
     4981 tgttgccagt tcatcttcgg tggactcgag tcagtcaagt tcagctggag taaatagttc
     5041 aaattcaagc tcagagagtt caagtacttc aagttcaaat tccagtgaag gtagtgttac
     5101 aagttcatcc tcggtagatt caagtcaaac aagttcagct ggatcaaata gttcaaattc
     5161 aaactcagaa ggttcaagtg cttcaagtcc aaattccagc gaaagtagta ttgccagttc
     5221 atctttggta gactcaagtc aatcgagttc agctggagta aatggctcaa gttcaaactc
     5281 agaaggttca agtgcttcaa gttcaaattc cagtgaaggt aatattgcca gttcatcttc
     5341 ggtagactca agtcaatcaa gttcagctgg agtaaatggc tcaagttcaa gctcaaaagg
     5401 ttcaagtgct tcaagtccaa attccagcga aagtagtatg acaagttctg gtgggacaag
     5461 tgattcaaat tcaaacaatg gtcaaactag tactacaagt tcatcttctg aaaattcaag
     5521 tcattcgagt ctgagttcaa atgaatcaag tagtgcaagt ttgacttcat ccgagtcaag
     5581 tggttcaaca acatcttcaa gtatgttgac taatccaaat ttacaatcta atgataaaaa
     5641 tggctcaagt ctaacttcaa atagttcgta tacttcagaa atgaaactaa ataacttgag
     5701 tgactcaaat ttaccttcga atgaagcaaa agtttcgact ttaatttcta aggtatcaag
     5761 tagtccgagt ctttcaaatt cattaagcgc aacaatctta caacttgtac caactgtaac
     5821 gaaagaagaa cttcccaaaa caggtgctga tgacgattta agtttagtat tagcagaatt
     5881 gggattaggc ttagtggcaa cgttaactat tggaaaagtt aaatataaaa aaaggttttg
     5941 agtagtatat tttaattaag gacttctttt cttttgaaag aagtttcttt ttaatttgga
     6001 attattcctt tattaaaaat tacgaacaat ttaaaataaa gaaagaaaaa ggaatgatga
     6061 tgattagagg atgaatgtta gcttatggta taatagttct atgaacttga tagatggaaa
     6121 agcacttgct gctaaaatgc aagctgagtt gaaagttaaa gtcgataaat taaaagaagc
     6181 ggacaatgtt ccaggtcttg ccgttattct tgtgggcgaa gatcctgcga gtcaaattta
     6241 tgtccgaaat aaagcacgac aagccacagc aattggttta aattctagtg tggttcgtct
     6301 accagaaact gtgtcagaac aagaactgtt agatttaatt gaacagtata atcagtcaga
     6361 acaatggcat ggtattttgg tacaattgcc attgccagaa catatttctg aagaaaaggt
     6421 tttactagct attgatccag aaaaagatgt ggatggtttt cacccaatga atatgggacg
     6481 tttgtggtct gggaatcctt tgatgattcc ctcaactcca gccggtatta tggaaatgtt
     6541 ccgagaatat gatgtggaac tttctggtaa acgtgcagtt gtgattggtc gttcaaatat
     6601 cgtcggaaaa ccaatggcgc aattattaat gatggctgat gctactgtga cgattgctca
     6661 ttcgaaaaca gaaaacttgc gcgaattgac taaggaagcg gatgttttgg tggttgctat
     6721 tggccgtgac cggatgatta aagctgagga tgtcaaagaa ggtgcagttg taattgatgt
     6781 tgggatgaac cgtgatgaag atggaaaact tcatggcgat gttgattttg atgaagtaaa
     6841 agatgttgca agtttgatta cccccgttcc tggtggagtt ggtccgatga cgattacaat
     6901 gcttatggaa cagacagttc gtgcagcaag tagaaaaatg aatgaaaata aatagttaat
     6961 taataaaaga gtaactaagt ttatagtaat ttctaaggac ttatttttaa gttagaagtt
     7021 ttttgaagat aaacttttta ctttttttcg attttagcag tagaaatttt actaacagaa
     7081 tgattagtaa aaagattaat tgagaactaa agagtgaggg aatgacagaa tatttatcag
     7141 tatcaacctt aacaaaatat ttaaaagcga aatttgaccg tgatccatat cttgaacggg
     7201 tttatttgac aggagaaatt tcaaatttta gaagaagacc aaatcatcaa tattttgcac
     7261 ttaaagatga gggcgctgtg attcaagcta cgatgtgggc gggacaattt cgcaaattag
     7321 actttgaatt agaagaaggg atgaaagttt tggctgtcgg tcgaatcagt atttatccac
     7381 cttctggctc ttattctata aatattgaaa gtttagttcc agatggcgtt ggagctcttg
     7441 cggttaagtt tgaacagttg aagaaaaagc tgactgctga agggctattt gaacaacgtt
     7501 ggaaacaaac tttgccacaa ttttctaaga aaatagctgt ggtaactagc ccgtcaggag
     7561 cggtcattcg agatattatc acgacggttc aacgtcgttt tccgatgagt caaatcgttc
     7621 tttatccgac aaaagttcaa ggacaaggtt cggctgaaga aattgctgga aatatccgtc
     7681 gagctaatca acgtggtgat tttgatgtca tgattattgg tcgtggtggt gggtctatcg
     7741 aagatttatg gggatttaat gaagaaattg tggttcgagc aatttttgaa tcacgtattc
     7801 caattatttc atcggttgga catgaaacag atgtgacttt agctgatttt gttgctgata
     7861 gtcgtgcagc gactccaaca gcagcagccg aattagcaac accaaatacg aaggttgatt
     7921 taataaattg ggcgaatgag caggaaaaac gactttttaa ccgcttaaca catttaatta
     7981 aaataaggcg tgaacgagta gataaattaa gccagtcaat cgtttttaga cagccagaac
     8041 gcttgtacga tggacactta caaaaacttg accgtctgtg tgaacgtttg gcagtgctga
     8101 cggaaaataa agttgcaaat atgaaacacc gttatgagct gtcagctggg aaattaattc
     8161 cgacttacgg aaagatagtt gaagctaaaa agaataagac ggagcaactt tatcagtctt
     8221 tacttttatt agatatctcg aaaataaaag cgcgtggttt ttccctcgtt actgacgaaa
     8281 agggaaagat tattaaatcc gtaagtgatg tgaaaaaagg tcagacttta gatgttgaat
     8341 tgactgacgg aaaagtaata gtggaggtaa aataatggca accaaaaaag aagatgtaaa
     8401 atttgaagat aatttggcag agttagaaaa tattgttcgt aagttggaat ctggtgatgt
     8461 agcattggaa gatgctattg ctgaatttca aaaaggaatg aaaatttcgg aaactttgaa
     8521 aaaaacactc aatgaagcgg aagaaacatt agtaaaaata gttggaaaaa atgatcagga
     8581 gagtgatttc tctccggaac agaaagacta ctaaaataaa aaacctttga tttttcaagg
     8641 ttttttattt taaacaaaat tttactgaca aaaaagccta ttattctaat atcaatctta
     8701 tttattatat actaataata gatagagtta tggtcaagtc ttttatagaa agagtagatt
     8761 aaatgaagaa aaaatttgta ttagcgccag attctttcaa agaaagttta agtgcgctgg
     8821 aagtttgtca agcaatggaa aaaggaatta aaaaagtttt tcctaaagct gaaataattt
     8881 ctatgccaat ggctgacggt ggtgagggga caacagatgc tttgattgat gcaacgggtg
     8941 gacgacgggt atataaaaaa gtacaaggtt catttgcaaa tacaaatgta gaggcctatt
     9001 ttggtatttt gggaaactca aatacggcgg tcattgagat ggcaaaggca aatggtctgg
     9061 aattggttgc tttggaagat agaaatccat tgattacatc aacctatgga acagggcaat
     9121 taattaaggc tgcaatggat gaaggagtag ataaaatcat cattggcatt ggtggaagtg
     9181 caactaatga tggtggctct ggaatggctc gtgctttggg agctaggttt ttaaataagg
     9241 accaagaaga aattccactt ggtggagctt tccttaaaga agtcagaaca attgatatga
     9301 gtgattttga cccaagagta gatgaaattg aaatattaat tgctactgat gtcaccaatc
     9361 ctttaaccgg aaataatggc gcttcttatg tttttggacc acaaaaggga gcaactgagg
     9421 aaatggtcaa aatattggat gaaaacttga agcattatgc agaaattgtt cataatgatc
     9481 tgggaataaa tgttaaaaat aaaccgggat ccggcgcagc aggtggtttg ggagcaggtt
     9541 tgcttgcttt taccaatgca aaaatgcaat taggaattga gcttgttgca caaacaatat
     9601 acttagaaga taaaattaaa gaaactgatt atgtatttac aggtgaaggt ggaatggatt
     9661 atcagacaaa atttggtaaa gcaccttatg gcgtctgtaa aattgctaaa aaatacaaga
     9721 aaccttgctt tgctttggca ggatatattg gggatggagc agatgttctt tatgaggaag
     9781 gaatgaccgc tatttttggt attttgagtc aagcacaatc tttgtcagat gccttggctg
     9841 acggcgcaaa gaacgttgag cgaacaagtg aaaatattac aagagtatta gcaatgaatg
     9901 agcaaaaggc tcacttataa aaagggaatg gatttaaaaa taaaaaaaat tcctcaaatc
     9961 atcacggttt ttagccgtga attttggtat aattagggta atggatacga agatactaaa
    10021 gttagaagat tttttaactg aattttatga aagcgctgaa tttccaactg gcttagccga
    10081 atcagcaaaa tattctttat tggcaggcgg taaacgaatt cgccctctcc tttttttaaa
    10141 cctattagag gcttttgatt tagaattgag taaggctcat tatcatgtgg cagccgcact
    10201 tgagatgatt catacgggtt ctttaatcca tgatgactta ccagcaatgg ataatgatga
    10261 ttatcgtcgc gggcagttaa ctaatcacaa gaaatttgac gaggcaactg caattttagc
    10321 tggtgatact ttattttttg atcctttctt tatcctttca actgctgatt tatccgcaga
    10381 aataatagta gcgttgacgc gtgaattggc ctttgcttca ggttcttatg gaatggttgc
    10441 gggtcaaatc ttggatatgg ctggtgaagg aaaagagttg acattagctg aaattgagca
    10501 gattcatcgc ttgaaaactg ggcgactttt aacttttcct tttgtagctg ctggaattgt
    10561 tgctcaaaaa tcaacggatg aagttgaaaa acttcgtcaa gtggggcaaa tattaggatt
    10621 ggcttttcaa attcgagatg atattttaga tgtcacagca acttttgctg agcttggaaa
    10681 aacaccaggt aaggatattt tagaggaaaa atcaacatat gttgctcatt taggacttga
    10741 gggagcaaaa aaatcactga cagaaaattt gtcagaagtt aaaaaattac tgacagactt
    10801 atcagttact gacagctctg aaatttttaa aattattgag caattggaag tgaaataaaa
    10861 aaaatagaaa tataaaaaga aattattagt tacatttcta agaaaaatac gtataattac
    10921 tataaagaaa gatctacatg aaagaaagaa ttgacgtact tgccacgaat caaggtttgt
    10981 ttgaaacacg agagcaagcc aaaagaggag taatggctgg tctagttgtt gatagtaaat
    11041 caggagagcg ttacgataaa cctggtcaga aaattgatga tggaacagaa cttcgtctta
    11101 aaggtgaaaa gttaagatat gttagtcgag gagggttaaa attagaaaag gctcttaaag
    11161 aattccattt agaaattaat ggaaaaactt gtcttgatat tggttcttca actggtggtt
    11221 ttactgatgt aatgcttcaa aatggtgcca aattagtcta tgctttagat gttggaacca
    11281 atcaattggc ttggaaaatt cgttcagatg aacgcgttgt cgttatggaa caatttaatt
    11341 tccgaaatgc tgttttagct gactttgaac aaggaagacc gtcatttact agtatagatg
    11401 ttagttttat ttctttagat ttaattctac cgccacttta tgaaattttg gaagaaaatg
    11461 gcgaagtagc agctcttatt aaaccgcagt ttgaagcggg acgtgaacaa gtcggaaaaa
    11521 atggaattat tcgtgaccct aaagttcacc aaatgactat tgaaaaagtt ttaaaaacag
    11581 ccactcaact tggtttttca gtaaaaggtt tgaccttttc gccaatcaag ggtggggctg
    11641 gaaacgttga atttcttgtc catttactta aagatggaaa agcagaaatt gctcagcagg
    11701 ttaatattga atcagtttta caaaaagaaa gtgaagaact atgaaaagag aagaccgatt
    11761 aaactttatt gctcaattta tccgtgaaaa cgaaattaaa acgcaagaag aacttgtgaa
    11821 taccctctta actcatggaa ttgacgttac tcaagcgacc gtttcccgcg atattaaatc
    11881 acttgcccta atcaaggtgc cagctgaatc tggtggttat cgttatgatt taccaaaaaa
    11941 caaggaagtt ttacagtcaa gccttcataa agccttagct tttgatgcaa ttacgggaac
    12001 aaaaatcaaa gataatatgc tctggattct tgctaatcca gggacaacaa gtcttgtgaa
    12061 aaattatctt ttggaagaat atagcgatga tattttttca atcattattg atgatgatag
    12121 tgctttagtt atttttgaaa tggaagaaga tgctaaaaat ctttataatt tactgacaga
    12181 attttaaatt tactgacaag aatattgtga caaaattctg ctgaatattt tgagcgaatt
    12241 aatagctgtc agtaaaaaaa gaatcaaagt aggaaagata aggttattgg gttactaata
    12301 gccttgtcat ttatttttga gaaaggaaat tttgatgtta caagagattt caatcaaaaa
    12361 ttttgcaatt attgaagaaa ttcatctatc ctttgagagt ggaatgacga ttttaactgg
    12421 ggaaactggt gcgggaaaat caataattat tgatgcaatg tctttattat taggtgggcg
    12481 tgcatcgagt gattttgtgc ggcatggggc aaacaaagcc gaaatagaag gtctcttttt
    12541 ctttgataaa actccagaat tgaaggcggt attattagaa cttggctttg aagaagtaga
    12601 ttctgaaatt attttaagac gtgagatttt tgctaatggt cgttccgttt gtcgaatcaa
    12661 tggtcaaatg gttaatttag ctacgctaag acaagtgggt gaattattag ttgatattca
    12721 tggtcaacac gatagccaag aattgatgaa tccgaaaagc catcttcgtt tacttgatga
    12781 atttggtgac gaagcctttg atcagataaa aaataattac aaactcaaat ttgaaaactt
    12841 caaaaatttg cgtcaacagc tcaatttacg acaaaaaaat gagcaagaat ttgctcaaag
    12901 aattgaaatt cttcaatttc aggctgaaga aattgaagcg gcggaaatta atcttgaaga
    12961 agatgaacaa ttagttaatc gccgagaaaa gttaaataat attaaaaata ttgctgattc
    13021 gcttagtagt gcttatctag cgcttgatga tgaagataat gattattcaa gtcttaataa
    13081 tatccgaaca acaatgacag aattggataa aattagtaac tttgataatg actatcaaga
    13141 acttgctgac aagacagctg aaagttatta tgtattagaa gaagttgcta atcaaattca
    13201 aagaatcatg agtgatttag aatttaatcc agctgaactt ttacaaattg aagaccggat
    13261 tatgaccttg accactttga agaaaaaata tggcccagaa ctgtccgatg tgatgaacta
    13321 tttagagaaa gtccaacttg aactctcaga actgacgggt tcggaaaatg actcagaaaa
    13381 tctagaaaat tcagttaaag ttgcacaagt tcaactcatt gaagcaagta aaaaacttaa
    13441 tgaagcgcgc cataaaattg ccaaagaagt tgaaaaagat attaaacacg aactttctga
    13501 gctttatatg gaaaaagctg atttcaaagt tagttttgaa ggggcaaagt tttcggcaaa
    13561 cgggaatgag catgttgaat tctttattca aaccaatccg ggagaaggat ttaaaccgct
    13621 ggcaaaaaca gcttcgggtg gtgaactttc acgtttaatg ctcgctataa aatcaagctt
    13681 ttcaagacgt gaaaataaaa cagccattgt ttttgatgag gtcgatactg gtgtttctgg
    13741 ccgtgttgct caagcgattg ctaataaaat atataaaatt gctagacatg ggcaagttct
    13801 tgcaatttct caccttccgc aagttgtggc cattgccgac agacaatttt atattgaaaa
    13861 agcttcaacc gatgacatta ctacttccac agttagaaaa ttaaacgctg aagaaagagt
    13921 aaatgaaatt gcgaaaatgc ttgctggtga agatttaact aaagaagcct tagctcaggc
    13981 taaacgttta ttgagcaaat aaatcgaata ttattaagaa aaagtcttga tttttaatca
    14041 gggcttttta tcttttaaat gacaaaatcg taattagtgt aaaattgcaa ccacaaatgt
    14101 gtatataccg aaaataataa atgttaaaat taaattgtag ttacactatt aaaaatattg
    14161 gagtatatgt gaaagtaaat aaaatttgga ttttaatcat tttggtctgt ttgttttttt
    14221 caatttatgg gcattataat caaaattatt ttttcttgtt cgtaggtatt gttggtgcct
    14281 gtgcgggaat aatctgtatg ttatgtgaaa tgctgattca aattcttaga aatcaaaaga
    14341 taaaaaataa attttaaaaa gctagtttta gataaatttc tttgatttgt tagcaaatgt
    14401 tactgacaaa ccttttaaaa agggctaaaa tatattcata agttatgtgc caacttccaa
    14461 gtcagagagc catagataaa aacgccttct cctatataag ataagggcgt ttttattata
    14521 aattcgaagc ctcatttatt ggggcttttt atctccaaag gagatattat gaagtaaaat
    14581 tagatttttt accattaaga acttctgtta aagttctttt atgaattaaa ctcaatatgt
    14641 tataatgaga tatcaaccat agtactgaaa ggagaggttt gtaatttaaa aactgaagtc
    14701 gtattttata atttaggagc taaaaatgag taaaacacgt ttagaagcat ttacggatgc
    14761 tatcatcgca attatcatga ctgtcttagt tttagaattg gtccgtccag attcagatag
    14821 cttacaaagt tttattgctt tacttccgca tctgggtgtc tattttgtaa gtttttttat
    14881 actggctatt tactgggtta atcaccatca tctttttcaa agcatcaaaa gaattaatgg
    14941 aaaagttcta tggataaata ttagttttct ttttgtctta tcacttattc ctattttttc
    15001 taactgggta tcaatctatc ctaattcatt tatcccagaa ttaggctatg tgattatctt
    15061 tttcttcggg aattttattt atctactttt gacaagagaa ttattgaaaa tcaatggaca
    15121 tcgtaaaacg tctgagacaa cgattagaaa aaatatccta agtgttgtgc tcaatattgt
    15181 cagtatttta ttaggttatt ttatagctcc agtaatcatg cttgttggtt cagccttaat
    15241 tttttcaatg tgggtgattc cagataaaaa tattgaaaaa atgtttaaat aatcttttaa
    15301 taaaaatatg agtttactta ataaaaaagt ttggaataaa taactgacct tttgtcagta
    15361 aataatatta taagtaaaga ggaataacaa tgattaaagc atacatcaaa tattggaaaa
    15421 aagcaggaga tttaaaatct tattcaaatc gttcggatta ttggtgggtt ttcttgacta
    15481 attcaatcat atttgcgatt ctcagcattt taaactttat ggtgacaatc cctaaagctg
    15541 ggaaaataat gagccaatct gcaactttat cacaaaaaga aattattcaa caggtgacag
    15601 acttatatgc caaccccacg ggtggcgcat tagtaatagt tattgttaca gctctcattg
    15661 gtctagctat tcttgttcct aatatcagtt tgacagctcg tcgtttacgt gatgctaggt
    15721 ttccttggtg gattgctctt gtttttggag tagctgcaat ttatgggctg gttacaatgt
    15781 ttattcatca agatcttcta gcaaaaatgg gttattttgt tggatttatc aatttcatta
    15841 tttatattct ttgccttttt ccaaccaaat atggcattga cgaagaagat gattcaagaa
    15901 cttatgaata attaaaaaat agagaggtaa aatatggttc aagcttataa aaaattttgg
    15961 ctgggagctt tcactttcaa taaaaaaacc agtcgtaaag atttttggtc agccttatta
    16021 actcatatca taatatttgt catcttgttt aaagcttatc atttctttaa tctactagat
    16081 ttttatcaac taacgacttt atggcaaact tttgcttcat tctttcaatt aatatttaat
    16141 ctatatttct ttggaagttt attgtccttc attgctctaa ctgttcggag attgaatgat
    16201 gcagatttac cttggggact tatttttctt aattttatcc ttggtctagg aactcttgtg
    16261 ctcttgatac ttaacctatt tccaagttcg cctagagctt taaaattcaa ggaatacgag
    16321 attaattctt ctcaagaatt taataattta ccagagacaa agacattatc aggtatattc
    16381 aaggactatt ttaaaaatta ctttgaattt cgcggaagaa cgacaagaag aaatttttgg
    16441 tgggtgcaac tgttttgggg actgaccgtt attctttttc tgtttttaat ctatcttttc
    16501 aatcaatttg aacaaataat gtttggctat aattttattg gtagtatggt cttgcgttta
    16561 ttctttttcc tatttatctt aggaacattt ttcccacaac ttacgattca tgtaagacgc
    16621 ttaagagatg ctggtttgag taatttagga ctatcacttt cgttaggtgg aacaagtgga
    16681 atattaattt tttatcaaat gttcacgaag acattaaaaa taacatatac aactggtcac
    16741 tatcaattag ttcaatatct cttattttta ctagtaatga ttgcagtatt gagtttaatt
    16801 cttgtagaag taatggcgac aggagaatta aaaacaaata aaaaaaattc tttatttgaa
    16861 aaatagactg attaatttca gtctattttt agtattaatt gttaaactat aaaaagtcac
    16921 gtttacacaa cttgtaaatt gaattgacat caaagaagtc agtaatagat acaaatgcag
    16981 ttcatgtaag cctttttatt aaaaaaatct ttacataatc atgtaaacta ctacaaaaat
    17041 agaaaaaaag tgatataata aactgtaagt atacaaggag gacggcgctc ttgccaaaaa
    17101 caatagcatt taagcatgat acagtcttac tacatgaaac cgtagatatg cttgaagtaa
    17161 agccaaatgg aatttatgtt gatgcgacac taggtggcgc aggacatagt gagtatcttc
    17221 ttagtaaact gactaatggt catctttatt catttgacca ggatgaaact gctcatgaaa
    17281 acgcaaaagt acgcttaagt gagcaacttg cagaagataa agtaacattg attaaaagta
    17341 attttcgcta tcttaaatca gctttagctg aattaggagt cacgaaaatt gatggaattc
    17401 tttatgattt aggagtttcc agcccacaat tcgatgatag tcaacgaggt ttctcttata
    17461 aaaaagaggc aagattagac atgcggatgg accaaaatca aacactttct gcttatgaag
    17521 ttgtaaatga atatccttac gaagcattag ttcgcatttt tttccgctac ggcgaagata
    17581 aattctctaa acaaattgct cgtaagattg aacaagcaag aaaaattaaa cctattgaga
    17641 caacaattga gcttgcagat ttaataaaat ctgcattgcc tcaaaaagaa ctcaagaaaa
    17701 aagggcatcc agccaaacgc attttccaag cgattcgtat tgaagtaaat gatgaacttg
    17761 gagcagcgga agaatcaatc gaacaagcca ttgatttatt aaaagttgat ggtcgaatct
    17821 cggtaattac tttccattct ttagaagatc gtttaacaaa aacaattttc aaagaatata
    17881 gtacagttaa tgttcccaag ggattaccga tgcttcctaa agatatggaa gctaaactaa
    17941 aattgattaa tcgcaaacca gttcttgcaa gcgaagaaga actcgaattt aataatcgag
    18001 ctcatagtgc aaaattaaga gtagcgcaaa aacaaagaga ttaatcaaat aacaagttgg
    18061 tctaataaag agggttttcc cacttgagga ttgtttttgg atgtcttata taaatgaaat
    18121 aacaatattt agcttttctc tttttaacag tgaagagagt aagttgaatt tctttagtaa
    18181 gataaacgag tggaggcaaa gatggcagca cagcctaaag aatacttcga tatagaaact
    18241 gcggcgaaaa aagatagtta tctcattgat acggaaactt tagcgccaga agttctagca
    18301 agtaagttta aaaagttttc tggtgttgaa aaggtattct atctgacaat ggtagttgct
    18361 gctttagtgt tggctgttgg tctactttat gttaagacta agacacttga agttcaaggg
    18421 aatacaatgg acttacgttc aaaaatttct caagaaacaa cccgaaaaac tgagtatgat
    18481 caacaaattt tagatttaac atcaggtact aaagtgcttg atacggcgaa taaagctgat
    18541 ttaaaacaaa atccttctaa tgtattgaaa gcaacgaaat gataaaattt ttaaaaaaac
    18601 taattttctt tccttttaga aaagtatcac gaaatgcccg aaaaacgaat tggagtacag
    18661 aaagaaatcg taaacgagta ggtaagagcc tgtttttcct agctattgcg ctgtttacgg
    18721 tttttatatt tcgttttgtc tggctaatta ccgtcaatca tgtcggtgga accaatctta
    18781 caacgatggc caagagcaac tatcaaagca cagaaacagt tcatgcgaag cgtggaacaa
    18841 tatatgaccg tacaggtgcg gctattgcgg tagactcaag tacctataca atttatgctg
    18901 taattgataa aacacaggtt gattcaaatg gaaatcctct ttatattgat aagaaagatt
    18961 ttaccaaagt tgaagatttc ttaaatagta aacttggaat tgaccgcgat ttaattaaaa
    19021 agcagctcaa ttctaaattg aaacaagttc aatttggccc taaaggtagt gatatctctc
    19081 ttgaaaaaat gaaagagatt caaaaagcgg ctgagaatga aaaaattgtt ggacttggtt
    19141 tcacggcaaa tatttctcgt tcttatcctt ttggaaattt tgcttctcaa tttattggta
    19201 ttgctcgtcc taaagatgaa aatggtactc aagctctcaa gggtgatatg ggcttggaaa
    19261 aagccttcaa taatgttttg agtggtgaaa atggtaaaga aacttatcaa aaagatatct
    19321 atggtcgccc aattccagga acaactaaag tcattgaacc tgttaaaaat ggtcaagacg
    19381 tttatactac acttgatgca caacttcaaa gaaatcttga aggatatatg gacaaggcgg
    19441 ctacggatac tggagcacaa caactttcag gaactttagt tgatgctcat accggtgaga
    19501 ttttagcaac aagtcaacgt ccaacctata cggcaacaac gatcaatgat gctgagaaac
    19561 aaaagtattt cacttggaac agtttgctct cacaatcagc ctttgaaccg ggttcaacat
    19621 ttaaaacttt cttgatggct ggagcgcttg atagtggaaa agtaaatctt aatgaaactt
    19681 accaacggaa acttcaagtt tatgatacaa cgattaatga ctgggatgta acagaaaata
    19741 aaagctatac tttgccagaa acagtaacct atgctcaagg ttttgcttta tcttcaaata
    19801 ttgggatgag taaaattgaa atgaatatgg gagatgcttt atggggaagt tatcttaata
    19861 aatttaaatt tggtcttaaa gtaagagccg gtttagatgg tgaaaatccg ggagcccttc
    19921 cttcatcaaa tgccgtttcg caaattcaat cttcatttgg tcaaggggtt gcggttactc
    19981 cacttcaatt gattagaggt tggacggcta ttgctggaaa tggaacaatg cttgagccac
    20041 atattgtcag caaagtagta gatccgaata caaaaacaag tttgacttct aaagcagaag
    20101 ttgttggaca tccggtctct aatgatgcag caagtggtgt gcgtgatttg atgttaacag
    20161 taaatactga ccctgtttac ggaacatctt attcaacaag tggcgattct gagcaaaatc
    20221 ttgctgctgg tcctttattt atggtcaatg gtgaaccggc tgcggttaaa acggggacgg
    20281 cccaaattgc ctcaacaacg ggtggttata tgacaggttc tcaagattac ctttactctg
    20341 ctgttgtgat gtatcctgct aagaatcctg attttatttt ctatatgaat gtaaaaattc
    20401 ctacagaaag ttggacactt aaatatattg ctcgagtggc aaatccattg ttaacaagtg
    20461 ctgaagcaat gaaaaatgat ttatcagtta gtgctgatac tgatactaaa gctggcaaag
    20521 tgaccattga gaattataaa ggcaaagatt caggagatac tgctgatagc ttacgccgta
    20581 ctgtccttag tccggttatt attgggacag gggcaaaagt aactgctcaa tcgattgctg
    20641 aaggtgaaaa agtttcagca aattcacgaa ttttactttt gacgaatgat aaagatcagg
    20701 tgatgcctga tatgtatgat tggtcgaaaa aagaagttga gcaattggct aattggtttg
    20761 gaattaaagt aacttatgaa gggtcaggaa ataaagtctt gactcaaagt atcgaaactt
    20821 ctaccaatgt taaaaaaggt caaactctaa ctgttaaa
//
