LOCUS       NZ_NTSF01000056        20148 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS021634
            AFS021634_110_H4_Contig56_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTSF01000056
VERSION     NZ_NTSF01000056.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 84374)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 84374)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.88x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563165.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 02:22:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,903
            CDSs (total)                      :: 5,824
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 84 of 212
            Pseudo Genes (incomplete)         :: 133 of 212
            Pseudo Genes (internal stop)      :: 67 of 212
            Pseudo Genes (multiple problems)  :: 60 of 212
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:49:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 64226
            Orig. end                         :: 84374
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTSF01000056.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20148
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..20148
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20148
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[10000:15239](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            390..950
                     /locus_tag="CN325_RS29330"
                     /old_locus_tag="CN325_29330"
     CDS             390..950
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017656373.1"
                     /locus_tag="CN325_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29330"
                     /product="GNAT family protein"
                     /protein_id="WP_098392268.1"
                     /transl_table=11
                     /translation="MENDNQVFWRTDCLILRRFSIDDTNYFHFYRSNPEVAKFQSWVNY
                     QYHEAETFVNEQVKNNPNLPGTWFQFAIALAENNKIIGDCALHTLVNEPRIVEIGFTLS
                     PEYQGKGYATEAVCALLNYIFHSLQKHKVIAFSDVRNNKSISVLERVGMRREGHLLQNY
                     MLKGQWIDEYQYSILKSEWKDAT"
     misc_feature    427..441
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.73"
                     /tool="antismash"
     gene            969..1070
                     /locus_tag="CN325_RS29335"
                     /old_locus_tag="CN325_29335"
     CDS             969..1070
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021546.4"
                     /locus_tag="CN325_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29335"
                     /product="DUF2179 domain-containing protein"
                     /protein_id="WP_098392269.1"
                     /transl_table=11
                     /translation="MKELIHEIDENAFVTVCDVAEVQGGNFKKHDIH"
     gene            1469..2311
                     /locus_tag="CN325_RS29340"
                     /old_locus_tag="CN325_29340"
     CDS             1469..2311
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="CN325_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29340"
                     /product="metallophosphoesterase"
                     /protein_id="WP_098392270.1"
                     /sec_met_domain="Metallophos_2 (E-value: 7.1e-10, bitscore:
                     31.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKIKRSVLIVATLVVCIIFLYLQNNLISITEVKITSSKIPSSF
                     KGYKILQISDLHNKQFGDNQDVLIQKIKSIDPDIIAITGDLIDSKSYDAEVSMQLIREI
                     VKNYPVYFVTGNHEQWSGKYNSLEKELKKYDVNVLRNEHVGIRKGEQEINLLGIDDPEF
                     VTGNRDEGNIIIDEIKKTKIEMQPDRYNVLLSHRPEFLTEYADEQIDLVLSGHAHGGQV
                     RLLFIGGLVAPNQGVLPKYTAGLYVEQNTSMVVSRGLGNSIIPQRILNRPEIVVVQLN"
     gene            2525..2776
                     /locus_tag="CN325_RS29345"
                     /old_locus_tag="CN325_29345"
     CDS             2525..2776
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="CN325_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29345"
                     /product="hypothetical protein"
                     /protein_id="WP_000548621.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDVARIRKYMNLKT"
     gene            2980..3705
                     /locus_tag="CN325_RS29350"
                     /old_locus_tag="CN325_29350"
     CDS             2980..3705
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001187059.1"
                     /locus_tag="CN325_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29350"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_001187075.1"
                     /transl_table=11
                     /translation="MQQPSIILRTVSKSFGKKEVLHNLSLQVEKAEIFGFVGPSGSGKT
                     TLIKMIAGINEATKGEVLVNNTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKSKKTRIAEVFELVQLSQYMKKQVQQFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGKLVAVGTTEELKK
                     RVSSGRIEDVFLLEEVVSS"
     gene            3702..4721
                     /locus_tag="CN325_RS29355"
                     /old_locus_tag="CN325_29355"
     CDS             3702..4721
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="CN325_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29355"
                     /product="ABC transporter permease"
                     /protein_id="WP_098392271.1"
                     /transl_table=11
                     /translation="MRVTGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYI
                     PQIAVVDMPAQIIKVMKNQEASIYEYSKENAISELEKQKIDAILQIENGKMKLLLEGSD
                     SSKNRAVLQVLQKSTEKNDVSIMKPEVNFLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPIRRWEIVAGYIIGFGIFAFIQSIIIVSFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPMESMNKW
                     LQMLGKVFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSILFAVGNVFALKKHRKI"
     gene            4746..5399
                     /locus_tag="CN325_RS29360"
                     /old_locus_tag="CN325_29360"
     CDS             4746..5399
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168192.1"
                     /locus_tag="CN325_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29360"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_001168192.1"
                     /transl_table=11
                     /translation="MQKDWLEELIAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQTFAKEIFKSEYESYEGLL
                     RVVIHNRFKFAQKHFPMIKILIQEVPFQPELKNEIQQLVETELFSHFKKLIVKFQEEGE
                     IIEIPPSSVLRLTLSAVLGLLLTRFLLLPEEKWNDEAEIENTIQFILYGLTPRI"
     gene            complement(5521..5820)
                     /locus_tag="CN325_RS29365"
                     /old_locus_tag="CN325_29365"
     CDS             complement(5521..5820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728146.1"
                     /locus_tag="CN325_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29365"
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_098392272.1"
                     /transl_table=11
                     /translation="MKRKLSSILSVLTLSIMFLGTSTQAEYDGNNMNRVNNTDISTRVN
                     DNNLDRVNNDVRTRNVNTTNDLNDNRDKNNNWAWLGLLGLAGLLGLRRRDKETR"
     gene            6054..7022
                     /locus_tag="CN325_RS29370"
                     /old_locus_tag="CN325_29370"
     CDS             6054..7022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="CN325_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29370"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_098392273.1"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEENGENRLVQPSTREDVTEKMEQFSNDFLQTISDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGAGLFGGAVVKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAYYKMIKHNKNMKELVSFQSDNKYLFMAYNQVKQKELGRIIANQKNEKIEVVFE
                     NYEKTLYELFMRAPRYTSNVNVCEHIFGYFKTKLKKQEKDHFIELLQKYAEKKIPLSSL
                     LTILKSWAIRFDEKYLLRQTYFEPYPEELVEISDSGKGRDY"
     gene            7239..8384
                     /locus_tag="CN325_RS29375"
                     /old_locus_tag="CN325_29375"
     CDS             7239..8384
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="CN325_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29375"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_000397282.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.5e-41, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.2e-28, bitscore:
                     89.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1e-58, bitscore:
                     190.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAVNGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            8400..9737
                     /locus_tag="CN325_RS29380"
                     /old_locus_tag="CN325_29380"
     CDS             8400..9737
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="CN325_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29380"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_000486742.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.7e-12,
                     bitscore: 38.4, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.9e-08, bitscore:
                     25.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 4.1e-08, bitscore: 25.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 6.5e-11, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCKEEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIASGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPSNVRIDHFLENHVTITPFYDPMIAKVIAHGETREEAISK
                     LHDALEELKVEGIKTNTPMLLQVLEDEVFKEGIYTTGFVTKQLVKK"
     gene            9764..9979
                     /locus_tag="CN325_RS29385"
                     /old_locus_tag="CN325_29385"
     CDS             9764..9979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="CN325_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29385"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_001987345.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIISE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     gene            10001..10912
                     /gene="mvaB"
                     /locus_tag="CN325_RS29390"
                     /old_locus_tag="CN325_29390"
     CDS             10001..10912
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="CN325_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29390"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_098392274.1"
                     /sec_met_domain="HMGL-like (E-value: 2e-49, bitscore:
                     160.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDSNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISVAAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVEQVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            10917..11705
                     /locus_tag="CN325_RS29395"
                     /old_locus_tag="CN325_29395"
     CDS             10917..11705
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 2.2e-75. Score:
                     245.1. Matches aSDomain:
                     nrpspksdomains_CN325_RS29395_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="CN325_RS29395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29395"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_000939793.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQI
                     SEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEKRKPMYKGE"
     aSDomain        10959..11678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN325_RS29395_ECH.1"
                     /evalue="2.20E-75"
                     /label="CN325_RS29395_ECH.1"
                     /locus_tag="CN325_RS29395"
                     /protein_end="254"
                     /protein_start="14"
                     /score="245.1"
                     /tool="antismash"
                     /translation="HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGA
                     GEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRIEGLQAFKEK"
     gene            11708..13249
                     /locus_tag="CN325_RS29400"
                     /old_locus_tag="CN325_29400"
     CDS             11708..13249
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012094296.1"
                     /locus_tag="CN325_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29400"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_098392275.1"
                     /transl_table=11
                     /translation="MLDQKQQSNSFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGSRTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQVCLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPNNYLEKTPLVTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRVIDEGSFYEVKKLFAQELITGLARIDGKPVGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAKKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            13299..15239
                     /locus_tag="CN325_RS29405"
                     /old_locus_tag="CN325_29405"
     CDS             13299..15239
                     /NRPS_PKS="Domain: AMP-binding (99-521). E-value: 8.4e-82.
                     Score: 266.8. Matches aSDomain:
                     nrpspksdomains_CN325_RS29405_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="CN325_RS29405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29405"
                     /product="AMP-binding protein"
                     /protein_id="WP_098392276.1"
                     /sec_met_domain="AMP-binding (E-value: 2e-89, bitscore:
                     292.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLYGWMKSLGYEDYETFYNKSIEETAWFW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNGGTCNVVESALSRWLADEETRIQPALQ
                     YEGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNDFIPHNYDFSWSTLEKEKPFIHAEEMQSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKGNVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNDVIEAAAIGVPDEVKGEVCHCFAVLREGIIFTEDLKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     aSDomain        13596..14861
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN325_RS29405_AMP-binding.1"
                     /evalue="8.40E-82"
                     /label="CN325_RS29405_AMP-binding.1"
                     /locus_tag="CN325_RS29405"
                     /protein_end="521"
                     /protein_start="99"
                     /score="266.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="QPALQYEGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRVTI
                     YMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIV
                     SLKDEVDKACEHCPTVEKVVIVRHAGNDFIPHNYDFSWSTLEKEKPFIHAEEMQSDDPL
                     MLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFG
                     SLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLK
                     SLEVFASTGEPWNPDPWMWLFETVGKGNVPICNYSGGTEISGGIFGNVLIKPIAPISFN
                     ASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVH
                     GDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       14085..14141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS29405_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="CN325_RS29405"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       14832..14894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS29405_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CN325_RS29405"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     gene            15574..15789
                     /locus_tag="CN325_RS31615"
     CDS             15574..15789
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237376.1"
                     /locus_tag="CN325_RS31615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000236251.1"
                     /transl_table=11
                     /translation="MVIMTLAIVPGESRSEAVTVTVPGPLAARNTAVKLPEALVMTARG
                     TMKARDGLLNEKLTTTPGVGLPFTNT"
     misc_feature    15809..15826
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            15835..16092
                     /locus_tag="CN325_RS31620"
     CDS             15835..16092
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002127494.1"
                     /locus_tag="CN325_RS31620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_255289936.1"
                     /transl_table=11
                     /translation="MVSLEVKVIDAGPAGRLNPVGPVDPVGPVDPVDPVDPVDPVDPVD
                     PVDPVGPVDPVVPVNPVGPVGPVDPINPVAPVEPVGPVGN"
     gene            complement(<16110..16166)
                     /locus_tag="CN325_RS31735"
                     /pseudo=""
     CDS             complement(<16110..16166)
                     /GO_component="GO:0043592 - exosporium [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03720.3"
                     /locus_tag="CN325_RS31735"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="exosporium leader peptide-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEFLSFAALNPGSIGPTL"
     gene            complement(16364..16732)
                     /locus_tag="CN325_RS29415"
                     /old_locus_tag="CN325_29415"
     CDS             complement(16364..16732)
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189674.1"
                     /locus_tag="CN325_RS29415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29415"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_098392278.1"
                     /transl_table=11
                     /translation="MGNIPKVSSHQSNPNIPSQQVNPNTQQGSIKKTRRRIITTLAFIL
                     PIIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSVKKDGHSLNKDVKALTSSEEEILKFA
                     RKLYGFSKQNETIFQITE"
     gene            complement(17124..17426)
                     /locus_tag="CN325_RS29420"
                     /old_locus_tag="CN325_29420"
     CDS             complement(17124..17426)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN325_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CN325_29420"
                     /product="hypothetical protein"
                     /protein_id="WP_176528029.1"
                     /transl_table=11
                     /translation="MKGGRNKCPGKMIAGVLRKNIVVMIGGVLRKSIVMMIGGNLKKTV
                     IVMMIGVLNEISVVVNVSLFVAIVKGKIGNIFDANLKERICILEPINTRMYYTKS"
     misc_feature    complement(17448..17461)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.44"
                     /tool="antismash"
     gene            17991..18347
                     /locus_tag="CN325_RS29425"
                     /old_locus_tag="CN325_29425"
     CDS             17991..18347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000535569.1"
                     /locus_tag="CN325_RS29425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29425"
                     /product="hypothetical protein"
                     /protein_id="WP_000535573.1"
                     /transl_table=11
                     /translation="MGSRFNNCKKKCTCKQDDCWEVFEECKKEQHEKCDNSCVQGIRDE
                     LKKLINRTVQINTEGRTYVGTVSSVSCDVVKLAAIPGSVGVIISICKIEAIFPPVTTVT
                     ADFDFNGIDVANKA"
     misc_feature    18362..18377
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     gene            18477..18986
                     /locus_tag="CN325_RS29430"
                     /old_locus_tag="CN325_29430"
     CDS             18477..18986
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593134.1"
                     /locus_tag="CN325_RS29430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29430"
                     /product="GNAT family protein"
                     /protein_id="WP_098392280.1"
                     /transl_table=11
                     /translation="MIKLETFKKSDYKQLINWINSEEFLIQWSGNAFTFPLDEQQLEKY
                     IESVNTLAFKVVDEETSDVIGHISLGQIDNINKSARIGKVLVGNTKMRGRSIGKHMMKA
                     VLHIAFDKLKLHRVTLGVYDFNTSAISCYEKIGFVKEGLLRESKRVGETYWNLWEMSML
                     EYEWKK"
     gene            19013..19600
                     /locus_tag="CN325_RS29435"
                     /old_locus_tag="CN325_29435"
     CDS             19013..19600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002043489.1"
                     /locus_tag="CN325_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_29435"
                     /product="hypothetical protein"
                     /protein_id="WP_176528030.1"
                     /transl_table=11
                     /translation="MLTKGDWWVVDNKTKIISVAAVSGGGKTTITERLKHEFKNSKALY
                     FDSYIFDNCPADICKWIDDGANYDEWVLTPLIYDIEQLIQNNSLDYIIIDYPFAYLNSE
                     MRKFIDVTIFIDTPLDIAMARRILRDFKEGTIDEIHNDLEHYMTYARKAYLEAIHTVKP
                     NSDIILDGSLSVSEIINHAVEELGRREVIING"
     gene            19652..>19926
                     /locus_tag="CN325_RS29440"
                     /old_locus_tag="CN325_29440"
                     /pseudo=""
     CDS             19652..>19926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288270.1"
                     /locus_tag="CN325_RS29440"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CN325_29440"
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYTLFQYNWQVRDDWFKRCEQLSEEDLLCKLVVF"
ORIGIN
        1 atgaaaggaa atgctacagg ggacaaactt attcgtgcag gcgtaccaac tgactgggta
       61 gttggagata aatcaggtgc tggcagttac gggacaagaa atgatattgc tatcgtttgg
      121 cctccaaata gagcaccaat tatcatcgca attttatcta gtaaagatga gaaagaggca
      181 acctatgata atcaactcat tgcagaggca actgaggtta tagttaaggc tcttaaataa
      241 taatctctca attctttatg taatataatt aagaacttgg aaagcgattc tttttaatgt
      301 gaaaagaatc gcttttttat aagcatgtaa actatttata catatgtaat ataaagatat
      361 aattaatgta gaaaagaggg tgaatagtta tggagaatga caatcaagtc ttttggagaa
      421 cagattgtct tattttgaga aggtttagta ttgatgacac taactacttt catttttatc
      481 gttctaatcc agaagtggct aaatttcagt catgggttaa ttatcaatat catgaggctg
      541 aaacgtttgt aaatgaacaa gttaaaaata atcctaatct accaggtact tggttccagt
      601 tcgcaattgc tttggctgaa aataacaaaa taattggaga ttgtgcactt cacacacttg
      661 taaatgaacc tcgcattgta gaaattggat ttactctttc tccagaatat caggggaaag
      721 gctatgcaac tgaagctgtt tgtgccttac tgaattacat atttcattca ttacagaaac
      781 ataaagtgat tgcattttcg gacgttcgaa ataataagtc tatttctgta ctagaacgag
      841 tggggatgag gagagaaggt catttattac agaattacat gctaaaaggc cagtggattg
      901 atgaatatca atattcaata ttgaagtctg aatggaagga cgctacataa ttttaaaatt
      961 tagaaacaat gaaggaactt attcatgaaa ttgatgaaaa tgcctttgtc actgtatgtg
     1021 atgttgcgga agtacaaggc ggaaacttta aaaagcatga tatccattaa ggatattaac
     1081 taacttaaat attgtataca tagttgatta ttgaaaaaga taaaaacctc accacatata
     1141 gatggacaaa tgctatttac taagatgtac aactgcaagg tacatagaac taaaactaag
     1201 atattcatac gaactcaaaa agccgaaatt ccttaacttg ggaatttcgg ctttaatgtt
     1261 atatgataga gttacgatta gaacagagcc aggcatgttt acttcaacag agtgatataa
     1321 gttattcagt tcctaaaatt agaaacttgt acttgattat catagttaaa tcaatttcac
     1381 tttaaaagag aaccgttaga taaaaaaaga aaaatctatt ggaatgtttt tgagaattgt
     1441 agtaatgatt aagattttag gagggaatat gagcaagaaa attaaaagaa gtgtattaat
     1501 tgttgctaca ttagtagttt gtattatctt tttatattta cagaacaatt taataagtat
     1561 aaccgaggtt aaaataactt ctagtaaaat accctcctct tttaaagggt ataaaattct
     1621 acaaatttca gacttacaca ataaacaatt tggcgataat caagatgtgt taattcaaaa
     1681 aattaaaagc atagatccag atattattgc aattacgggt gatttaattg acagtaaatc
     1741 atatgatgca gaagttagta tgcaattaat acgagaaatt gtaaagaatt atcctgtata
     1801 ttttgtgaca ggaaaccatg aacaatggtc tggaaagtat aacagtttag aaaaagagtt
     1861 gaagaaatat gatgtcaatg tattaaggaa tgaacatgta ggcattcgaa agggtgagca
     1921 agaaataaac ttgctaggta ttgatgatcc agagtttgtt actggaaacc gtgatgaagg
     1981 aaatattata atagatgaaa ttaaaaaaac gaaaattgaa atgcagccag atagatataa
     2041 tgtattatta tcccataggc ctgaattttt gacagagtat gctgatgagc aaatagattt
     2101 agtgttatca gggcatgctc atggagggca agttagattg ctatttatcg gaggattagt
     2161 tgcgccaaat caaggtgttt tacctaaata tacagcgggt ttatatgtag aacaaaatac
     2221 atcaatggta gtgagtagag gattaggaaa tagtatcatt ccgcaaagaa ttttgaatag
     2281 gccagagatt gtagtcgtgc agctaaatta agctgtacga tttttttata caataatcag
     2341 taaaggggtt tatgtatttt gcaggagtaa acattacaat tttgttaaaa attttctacg
     2401 ttacataaag taacaaaatt tgaccctgat tgtttgttat agtgtaaata atcaaaaaac
     2461 ttaaaatttg tcgagtgaaa attgtgataa gtaattcatg taaaaaactt aaaggggtgt
     2521 acacatgcat aaagaatatg aaattgaaga atacacggcg attgaggaac aaatacatta
     2581 ttattgtaaa tgtttattag taagtcatcc tgatcaaata ataaagtatt tagaaaaaag
     2641 gttagaaaaa tatgcagaaa cattacaata tgcacattta tatcctgaca cagttatttt
     2701 accgttacag caattagtta ttgaatattc tttagatgtt gctagaattc ggaagtatat
     2761 gaatttaaaa acgtaaagtg aaatttatag tttaaatgaa acagagtcga ctttaggaaa
     2821 tgaaattcca atgtcgactc tgtttcattg tttaatatcg ttgattgaac atacatacat
     2881 acatacatac atactaatca atgaagtttg acatataatt aagcaagggt aaaataaaag
     2941 tgagtactca ctcattttat tggaaaagga ggatgaaacg tgcaacaacc ttcaattatt
     3001 ttacggactg tatcaaaaag ttttgggaaa aaagaagtgt tacacaatct ttcattgcaa
     3061 gttgaaaaag cagaaatttt tggttttgtt ggaccttctg gatcggggaa aacaacgctc
     3121 attaaaatga ttgcaggtat taatgaggca acgaaaggtg aagtgcttgt taataatact
     3181 aatatgccta atttaaatga aatgaaaaga attggttata tggcccaggc ggatgcatta
     3241 tatgaagaat tgtcagcata tgaaaatgca gattttatag caacgatgta tggactaaag
     3301 ggaaaaagta agaagacaag aattgcagag gtttttgaac ttgtacaatt gtcacagtat
     3361 atgaaaaagc aagtacaaca attttcaggt ggaatgaaaa aacgcttatc attagcaata
     3421 gcactccttc acgaaccaga aatattaatt ttagatgagc ctacagtggg gatagatccg
     3481 cttcttagaa aaacgatttg ggaaaagttt tatgacctta aaaagaaagg tacaacgatt
     3541 attgtaacga cgcacattat ggatgaggct gaattttgtg agcgtctagg attaattaga
     3601 gaagggaaac tagttgcggt tggaacaact gaagaattga aaaaacgcgt gtcatctgga
     3661 cggattgaag atgtcttttt gttggaagag gtggtgtcat catgagagtt actggtgtaa
     3721 tcattcgtat tattcgccaa ttttttcgag ataagcgttc gttagcgatg atgtttgggg
     3781 caccaatgtt attactttgg ctattatcgc tagtgtttac acaaaaagac tatataccgc
     3841 aaattgctgt tgttgatatg cccgctcaaa taataaaagt gatgaaaaat caagaagcgt
     3901 caatttatga atacagtaaa gaaaacgcga tttctgagtt ggaaaaacaa aagatagatg
     3961 caatacttca aatagagaat ggaaaaatga aacttctgtt ggaaggtagt gattcgtcaa
     4021 aaaatcgtgc tgtacttcaa gtattgcaaa aaagcacaga gaagaatgat gtatcaatta
     4081 tgaaacctga agtaaatttt ttacatggct ctaaagactt tacgatgttt gatgggcttg
     4141 gccctgtatt aattggtttc tttacatttt tctttgtatt tatattatca ggtgtatctt
     4201 tcgtaagaga acgtttaagt ggtacgctag aaaggttatt atccacccca ataagaagat
     4261 gggaaatagt cgcaggttat attattggtt ttggcatctt tgcctttata caatccatta
     4321 ttatcgtaag tttttccgtt tatattttag atttatacgt agctggctct atatggctaa
     4381 cgctacttat tacatgtatg ctctctttaa ctgcactaac attaggtacg tttttatcgg
     4441 catacgcaaa taatgaattt caaatgattc aatttatacc gcttgttatt gtgccacaaa
     4501 tcttcttttc tggattgttt ccaatggaat ctatgaacaa gtggctacaa atgttaggga
     4561 aagtatttcc actcacatac ggcgctgacg caatgagaca agtgatgatt cggaatcaag
     4621 ggtttacaga gattgcatta gatcttactg tattattact tttttcaata ttatttgcag
     4681 taggaaatgt atttgcttta aaaaaacatc gcaaaatata ataatgacaa aaaggggctt
     4741 tataaatgca gaaggattgg ctggaggaat taatagctgc aactaatacg gataaacgaa
     4801 atgaacgtca aatgcgaata ttagaggcgg ctgttgatat gtttggagaa aaaggatacg
     4861 cttcaacttc aacaagtgaa attgcaaaac gggctggtgt agcggaagga acaatcttcc
     4921 gctactataa gacgaaaaaa gatttattac tagcggtcgt aatgccaact ttaactaagt
     4981 tcgctgcacc atttttcgta caaacctttg caaaagaaat atttaaatcg gagtatgaat
     5041 catacgaagg acttttaagg gttgtaattc ataataggtt taaatttgct caaaaacact
     5101 ttcctatgat aaaaatatta attcaagagg tgccattcca accagaactg aaaaatgaaa
     5161 tacagcaatt agtagaaaca gaactgtttt cacatttcaa aaagttgatt gtgaaatttc
     5221 aagaagaagg ggaaattatt gagataccac catcttccgt actacgtctt actttatcag
     5281 ctgtattagg tttattatta acacgatttt tattattgcc tgaagaaaaa tggaatgatg
     5341 aagcggaaat tgaaaatacg attcaattta tattgtatgg attaactcca cgaatttaat
     5401 cgttgaagtg tgaattacat acataacttt taagtaaaaa taaatcgcct ttaaaaaggc
     5461 gatttatttt cattatatat ttttgataaa taagtgcttg tttactaaaa acattctaaa
     5521 tcagcgtgtt tctttgtctc ttcttctaag acctaataat cctgctagtc ctaataaacc
     5581 aagccaagcc caattattat ttttatcacg attatcattt aaatcatttg ttgtatttac
     5641 atttcgagtt cttacatcat tattaactct gtctaagtta ttgtcattta ctcgagttga
     5701 aatatcagtg ttattaactc tattcatatt atttccatcg tattcagctt gcgtagatgt
     5761 acctaaaaac ataatagata gtgttaaaac actcaaaata gatgataatt tccttttcat
     5821 aacaatccct cctttcttaa tcattaattt ctccgaagca tgtgtgtatt attcatttca
     5881 caatatctaa gccctcatta atagggcgca catttataga aaatagagtt gaatgattgt
     5941 taatgtatca ttggatttat atttctcata aaaataactg aatcaaactt tgcttaaaat
     6001 gttaatctta gtacaattta tattatacgg actagtaata aggaggtaat aagatgcgac
     6061 aatttgcaaa acctacaatc gtcgtaagta aatgtttaga atttgatgct tgtcgttata
     6121 atggagagat gattccagat gtaacaatac gaaatttgca gccatttgtt acatttatac
     6181 ctgtttgtcc agaagtcgag attggattgg ggactcctcg tgaaacgata cgaattgtag
     6241 aagaaaatgg tgagaataga cttgtgcaac cgtcgacacg agaagatgta actgaaaaaa
     6301 tggagcagtt ttcaaatgac tttttacaaa cgatatcgga tgtggatggt tttattttaa
     6361 agaatcgttc accaagttgt ggtacgcgtg atgtgaaaat ttattctggt tttgaaaaag
     6421 cgccagcaaa gggaaaagga gctggcttat ttggcggagc agtagtaaaa aaattttcgc
     6481 atcttcctat tgaagaggaa ggtagattgt cgaattttat tattagagag catttcttta
     6541 caaggctatt tacaatcgca tattacaaaa tgattaaaca caataaaaat atgaaagaac
     6601 ttgtatcgtt tcagtcggat aataaatatt tatttatggc atataatcag gtgaaacaaa
     6661 aggaattagg tcgtataatt gcaaatcaaa aaaatgaaaa gattgaagtg gtatttgaaa
     6721 actatgagaa gactttatat gaattattta tgcgtgcgcc ccgttataca tcgaatgtaa
     6781 atgtatgcga gcacattttt ggatatttta aaacaaagtt aaaaaaacaa gaaaaagatc
     6841 attttataga actgttacaa aagtatgcag aaaagaaaat accacttagt agtttactta
     6901 caattttaaa atcatgggct attcgatttg atgaaaagta tttattaaga caaacatatt
     6961 tcgaaccata ccctgaagaa ttagtagaaa tttctgattc cggaaaaggt agagattatt
     7021 aaacaataaa ttacataatt cgacacaaaa cctcctatgt tgttgtagaa caatgtagga
     7081 atttttttgt gcattagtac agaatctgtt ttaaaattaa gttatgacag aattgtagca
     7141 attgtctaac taatattctt gtcttttaag ttgttatgtt tgtagtagaa actcgcacgc
     7201 tgtcgaaact caatattcga taaggggtgt gtagcggaat ggaatttact ctaactcgcg
     7261 aaaaacaaat gattaaagaa atggtacgtg actttgctga aaaggaaatc gcaccgaaag
     7321 ctgtatatta tgacaaaact gcagagtttc catatgaaac atttcaaaaa atgggcgaac
     7381 taggattact aggcatccca ttcccagaag agtatggagg ttcaggtggc gatacagtat
     7441 cgtatgcgtt agcagttgaa gaaattggtc gcgcttgtgg tggcactggt ttaagctatg
     7501 ctgcaacaat ttcattaggt gcttctccaa tttattattt cggtacagaa gaacaaaaac
     7561 aaaagtattt agttccaatg gcgtcaggta aaacattagg tgccttcgga ttaacggagc
     7621 cgaatgctgg atctgatgca ggtggtactc aaacgaaagc ggtattagat ggcgatgagt
     7681 atgtaatcag tggtgagaag tgttggatta caaacgcaga gtatgcaaat acaattattg
     7741 taaccgctgt caatggcgtt gaagagaatg gtagaaaacg tatttctgca tttatcgtgc
     7801 ctactactag tgaaggatta acgatttcaa gtccatacga taagatgggt gttcgtgctt
     7861 ctaatacttg tgaaatcgta cttgatggtg tgcgtgtacc gaaagaaaat attcttggtg
     7921 atgtaaataa aggttttaaa caatttttat atacacttga tggagggcgt atttcaatcg
     7981 cagcattggc agttggtatt gcgcaatcag cctttgaacg tgcattgcaa tatgcgaaag
     8041 aacgtcaaca atttggaaag tcaatctcta atttccaagc gattcaattt aaattagctg
     8101 atatggcgac tgaagtagag ctagcacgca atttagtaca taaagcagct tggttaaaag
     8161 ataacgataa acctttcggc aaagaagcgg caatggcaaa actatttgca tcggaagcag
     8221 caagccgtat tgcgaatcaa gcagtacaga ttcatggtgg atatggttat atgcgtgaat
     8281 atgaagttga acgacatatt cgtgatgcaa aactattaga aattggtgaa ggaacttctg
     8341 aaattcaacg tctcgtaatt gctagacatt taggatgtag ataaaaggga ggaatcacta
     8401 tgtttcaaaa aatattaatt gcgaatcgcg gggaaattgc tgttcgtatt atgaaaactt
     8461 gtcaaaaact tggcatacgc actgttgcta tttattctga agcagatgaa aatgcccttc
     8521 atgtgaagat ggcaaatgaa gcttacttag taggtggacc gcgtgttcaa gaaagttatt
     8581 taaaccttga aaaaattatt gaaatagcta agaagacaaa tgcagaagcg attcatccag
     8641 gttatggttt attatcagag aatccgtctt ttccggttcg ttgcaaagaa gaaggaatcg
     8701 tatttatcgg tccttcagaa gaaatcatta cgaagatggg aagtaaaatc gaatcacgta
     8761 tcgcaatgca agcagcagat gtcccagtag tcccaggtat tactacaaat attgaaactg
     8821 ctgaagaagc aattgaaatt gcaaaacaaa ttggttatcc attaatgctt aaggcatccg
     8881 caggcggcgg aggcattggt atgcagttga tggaaactga gcaaacgctc accaaagcgt
     8941 ttgaaagtaa taaaacaaga gcgcaaaact tcttcggtaa cggagaaatg tatttagagc
     9001 gatatatagc agacgcgcat catattgaaa ttcagctttt agcagataca catggtaaca
     9061 cagtgtattt atgggagcgt gaatgttcgg tacagcgccg aaatcaaaaa gtaatcgaag
     9121 aagcaccttc accattttta gatgaaggta cacgaaaggc gatgggagaa gttgctgtac
     9181 aagctgccaa agcacttggc tatacaaatg caggtacagt tgagtttctt gtagatgatc
     9241 agaagaactt ctatttctta gagatgaata cgagattaca agtagagcat ccagtgacag
     9301 aagaaattac gggattagac cttgtagaac aacaactcct gattgcaagt ggagagaaac
     9361 tatcatttac tcaagatgat gtaaaacgta gtggtcatgc cattgaagct cgtatttatg
     9421 cagaggatcc gaaaacattc ttcccgtcac ctgggaaaat tacagattta acattaccgt
     9481 caaatgtacg gattgatcac ttcttagaaa atcatgtaac gattacacct ttctatgatc
     9541 caatgattgc gaaagtcatt gcacatggcg agactcgtga agaagcaatt tcaaaattac
     9601 atgatgctct agaggaatta aaagtagaag gtattaaaac gaacacacca atgctactgc
     9661 aagttttgga agacgaagtg ttcaaagagg gtatttatac aacaggcttt gtaacgaaac
     9721 aactcgttaa aaaataagat ttaacaatat taagggggaa aaaatgatga cgaaagtata
     9781 cgcatcgatg gcaggaaacg tttggaagat tgttgtagga gtaggagata cagtagagga
     9841 agagcaggat gtcgtcattt tggaatctat gaaaatggaa attccaatca tttcagaaga
     9901 agctggcaca gttatgaaaa ttaatgtgca agaaggcgat tttgtaaatg aaggagatgt
     9961 attattagaa atcgaatagg gagatatagg gggaagcgaa ttgaaactac ctaattttgc
    10021 tgtcattaaa gaagtcgggc cacgtgatgg cttacaaaat gaaaaaaaga ttgttggcac
    10081 aaaagataaa gtaaaatgga ttcaactact tacagaagca ggattgtcgt atgttgaagt
    10141 ttcctcattc gttcatccaa aatgggtccc tgcattagcg gatgcaaatg atgtattttc
    10201 tgagctgaaa agggattcaa atgttacata tgctgcgctt gttccgaatc aaaatggttt
    10261 ggaacgagct tttttgcaaa atgtagatga ggtgaatgtt tttttatcag caagtgaatc
    10321 tcataataaa agtaatatta ataaatcgat taaagaagca ttagttgtaa ttgaagatat
    10381 aacaaaacag gcattattcg aagggaaaaa ggtaagaggc tatgtttcta ctgtatttgg
    10441 atgtccttat gaaggggata taagtgtcgc agcagttgac gaattatgta atcaactatt
    10501 ttcatacggc atttatgaag tttctcttgg ggatacaatc ggtgtagcga atccattaca
    10561 agtagaacaa gtattagaac atctattaaa gaagtatgat gcttcgcagt ttgccatgca
    10621 ttttcataat acgtatggaa tggctctagc gaatgtagtt aaatcattag aatacggtat
    10681 tacaacgttt gatagttctt gtggtggact cgggggctgc ccttatgcac caggagcatc
    10741 aggtaatgtt gccactgatg acctagtaca tatgctccat aaattaggag tccaaacgaa
    10801 tatagacgaa gaaaagttat tgagagctag tcaatttatt caaagtaagt tgaatatcca
    10861 attaccgagt catgtgtata gagcgcttca acataaaacg ataagtaggt gagaagatgc
    10921 tacaattaca aaacatttca gttgattatg taacacctca cgtagtaaag atttcgttaa
    10981 atcgtgcaag acaagcaaac tcattatctt tggcattatt agatgaacta caaacgatat
    11041 taactcaaat aagtgaagat tcaaacgcac gtgtagttat tttgactggt gctggtgaaa
    11101 aagcattttg tgctggtgca gatttaaaag agcgtgccgg tatgaatgaa gaacaagttc
    11161 gccatgctgt tagtatgatt cgcactacta tggagatggt tgaacaatta ccacagccag
    11221 ttattgctgc tataaatgga attgcacttg gtggtggtac ggaattaagt ttagcttgtg
    11281 attttagaat tgctgctgaa tctgcaagtc ttggtcttac tgaaacgaca cttgcaatta
    11341 taccaggagc aggtggtaca cagcgcttac cgagattaat tggtgttggt agagcgaaag
    11401 aattaattta tacaggtaga cgtatttcag cgcaagaagc aaaagaatac ggtttagtag
    11461 aatttgttgt accagctaat ttacttgaag agaaagcgat tgaaatagca gagaaaattg
    11521 ctagtaatgg acctattgct gttcgattag caaaagaggc aatttcaaat ggtattcaag
    11581 ttgatttaca taccggatta caaatggaaa aacaagcgta tgaaggtgta atccatacga
    11641 aagatcgaat agaaggatta caggcattca aagaaaaacg caaaccgatg tataaggggg
    11701 agtaaatatg ttagaccaaa aacaacaatc taattcattt gaagaacgag ttgaaacaat
    11761 taaacaaggc ggggcaccga aatatcatga gcaaaataaa gcaaaaggaa aattatttgt
    11821 tcgagatcgt ttagcgcttc tatttgataa tggcgaatat gtagaagatg cattatttgc
    11881 taactgtgaa caaacaggct tacctgcgga tggcgttgta acggcaacgg ggaaaataca
    11941 tggtcgtact gcgtgtgtaa tggccaatga ttctactgta aaagctggat catggggatc
    12001 acgcacagtt gaaaagattt tacgtattca agaaacagct gaaaaactac gtgttccgtt
    12061 attttattta gtcgactctg ctggagcacg tattacagat caagtagaaa tgttcccagg
    12121 gcgccgcggt gcaggaagaa tcttctataa tcaagtgaag ttatcaggta aagttcctca
    12181 agtatgcttg ttatttggac cttctgcagc tggtggtgcg tatattccag ccttttgtga
    12241 cgttgtaatg atggtagaag gaaatgcatc tatgtattta ggatctcctc gtatggctga
    12301 gatggttatc ggtgagaagg taactttaga agagatgggc ggagctcgta tgcattgctc
    12361 tgtatcagga tgcggagatg ttttatgtaa gacagaagaa gatgcgatta cacaagcaag
    12421 acaatacatt tcatattttc caaataacta cttagaaaag actccattgg ttacacctca
    12481 agaaccgaaa caattcgata aaacgttaga acaaatcatt ccagaaaatc aaaatgctcc
    12541 tttcaatatg aaagatctca ttaatagagt tatagatgaa ggttcattct atgaagtaaa
    12601 aaaattattt gctcaagagc taattacagg cttagcacgt attgatggta agccagttgg
    12661 tattattgca aatcagccgc gtatgaaggg cggcgtatta ttccatgatt cagctgataa
    12721 agctgctaag tttattaatt tatgcgacgc atatcatatt ccattattat tccttgcgga
    12781 tgtaccagga tttatgatcg gtacaaaagt agagcgtgct ggtattattc gccacggtgc
    12841 aaaaatgatt tctgcaatga gtgaagcgac tgtaccgaag atttctatcg ttgttcgtaa
    12901 agcatatggc gctggtttat atgcgatggc aggtccagca tttgaaccag attgctgcct
    12961 ggcattaccg acagcctcta ttgcggtaat gggtccagaa gctgcagtta atgctgtata
    13021 tgcaaataaa attgcagctt taccagaaga agagcgtgct agcttcattg ctaaaaaacg
    13081 tgaagagtat aagaaagata ttgatattta tcatttagca tcagagatgg tgattgatgg
    13141 tattgttcat ccaaacaatt tacgtgaaga gttaaaagga cgtttcgaaa tgtatatgag
    13201 taaatatcaa gtattcacgg atcgtaaaca tcctgtatat ccagtttaaa agccctattt
    13261 agggctttct tgctcaaaaa gttaaggagg ggaaaacatt gaaacaagca gtttggtttc
    13321 caacagaaga gtacaaggaa aaaacacgtt tatatggttg gatgaaatca ttgggatatg
    13381 aagattatga aactttttat aataaatcta ttgaggaaac agcttggttt tggggagagg
    13441 cagaaaaagc agttggctat caatggatga aaccttatac agaagtgtta gatttagaaa
    13501 atggtacacc gtttgcacag tggtataatg gcggaacatg taacgttgta gaatcagctt
    13561 tatcccgctg gcttgcggat gaagagacga gaatacagcc agcacttcag tacgaagggg
    13621 aaaatggaac ttcaaaatca tttacatatg aagagcttga caactgggta agccgtgttg
    13681 caaatggttt gaaacacgcg ggtattgaga aaggtgaccg tgtaacaatt tatatgccga
    13741 tgattccaga aacagttgtt gcgatgctag ctgtaatgaa aatcggagca attatttcac
    13801 caatattctc aggctttgcg tctgatgcag ttatgacacg tgtgcaagcg gcaggttcaa
    13861 aaatgattat taccgcagat ggattttcac gccgcggtaa aattgtttct ttaaaagatg
    13921 aagtagataa agcttgtgaa cattgcccaa ctgttgaaaa agttgttatc gttcgtcatg
    13981 caggaaatga ttttatacca cataactatg acttttcgtg gagtacgcta gaaaaagaaa
    14041 aaccattcat acatgccgag gaaatgcaaa gtgatgatcc attaatgctc atttatacat
    14101 caggaacgac tggtaagccg aaaggaacag tacacacgca tgcaggattt cctttgaaag
    14161 cagcttttga tgcaggattt ggaatgaata ttaaacaagg tgatcgtgta ttatgggtaa
    14221 ctgatatggg ctggatgatg gggccgtttc tattattcgg ttcactcatt aatggagcaa
    14281 cgatggttat gtacgaaggt gttccagact tcccagaagc agaccggtta tgggagacag
    14341 ttgataaata tgaaattact catctaggta tttcgccaac gttaatccga gcattaatgg
    14401 caaaaggtga tgagtatgtc aataaacatt ctttaaagag tttggaagta ttcgcatcaa
    14461 caggagaacc ttggaatcct gatccatgga tgtggctgtt tgaaacagtt ggaaaaggaa
    14521 atgttccaat ctgtaactac tcaggtggaa ctgaaatctc tggtgggatt ttcggtaatg
    14581 ttcttattaa gccaatcgca ccgattagtt ttaacgcatc tttaccagga atggcagctg
    14641 tcgtactgga tgatcaaggt aaaccaattc gagatgaagt cggagaatta tgcttagaga
    14701 aaccttgggt aggtatgacg aaaagcttct gggaagatga tgaacgttac gtgaacacat
    14761 attggtcgcg ttttgaaaat aaatgggtcc acggtgactg ggtcatttac gatggtgaac
    14821 aatatatcat cacagggcgt tcagacgata cgttaaatat tgcaggtaaa cgtattggac
    14881 ctgctgaata tgaatctatt cttgtgaaac ataatgatgt aatcgaagct gctgcaattg
    14941 gtgtacctga cgaagtaaaa ggtgaagttt gtcattgctt tgctgtatta cgagaaggga
    15001 taatatttac agaagattta aagaaagaat taatgagttt agtaaactca catattggaa
    15061 aagcgttgtg tcctaaagac atccacgttg tagaagattt accgaaaaca cgtaattcta
    15121 aagtaatgcg ccgtgttatt aaagcagctt atttaggaaa agaattaggt gatttgtcgt
    15181 cacttgtaaa tcctgaagta gtaccgttta ttcagggatt acagtctagt aaattataaa
    15241 gttagcaagg agttctatat aaatagagct ccttttttat gtttataaaa agagaagaag
    15301 tgaagttgat gaagaagaaa aattttacta ttagtgttaa gtatgtctgt tttataattt
    15361 ttattaaaat acgatactgt ggcatctttg ttcattagag taattaaatt ttgttaagga
    15421 tgaaattcaa tgaaagcgtt attttaatag attgttacga aatttaattt gaaaggcaca
    15481 tccaaatgat aaaaaaagag cactataaat cagtgctctt tttattagaa attgcttagt
    15541 tcttaaaaat aaaattatta cggacaattc acaatggtaa taatgacgct agccattgtt
    15601 ccaggagaat caagaagtga agcagtaacg gttactgttc caggcccatt agcggctaga
    15661 aataccgcgg taaagttacc tgaggcattg gtaatgacag caagaggaac catgaaagca
    15721 agagatgggt tactaaatga aaaactgacc actacccctg gagtaggact accgtttact
    15781 aatacttgac ccgaaaaaaa taaagtatta tttccttgag tggatacaca tgctgtggtt
    15841 tcgttagaag tcaaggtaat agatgcaggt ccagcaggaa gattaaatcc agttggccca
    15901 gttgatccgg ttggtccagt tgatccggtt gatccagttg atccggttga tccggttgat
    15961 ccggttgatc cagttgatcc ggttggtccg gttgatccag ttgttccggt taatccggtt
    16021 ggcccagtcg gtccagttga tccgattaat ccagtagctc ctgtagaacc ggtgggaccg
    16081 gtagggaatt gaaaaggttg aacaggtgga agtgtaggtc caatagaacc cggattaagt
    16141 gcagcaaaag ataaaaactc gtccattatt tatcacctct aaaaatcgta ttactaatag
    16201 taaatgtaat gatagagcaa agtgaaacag acaagtggtt gtattttaac aaattaaaca
    16261 aagtagttat atgatagaaa gagagattag tatgattcct ttagaaatta aatataaaaa
    16321 ggcgattatc ttcaaatcgc cttttaggta atgccgtgta attttattca gttatttgaa
    16381 atatagtttc attttgtttg gaaaatccat acagtttcct tgcgaatttt aaaatttctt
    16441 cttcactact tgttaaagcc ttgacatcct tgttaaggga atgaccatcc ttctttacag
    16501 aagataattt ttgttgttcc gtattaagtg tgatttgttt ttctttaatc atttcttgtt
    16561 ggttattcag agaatattga aggacaaaaa ttataggtaa tataaaagcc aaagtagtta
    16621 taatacggcg tcttgttttt ttaatactac cttgttgggt attaggattc acttgctgtg
    16681 agggtatatt aggatttgat tggtgtgatg atacttttgg gatgtttccc attaaaatgc
    16741 ctccattact gattgtcgaa tttaaaccgt ttaatagtat tataaatgtt caataaggat
    16801 tttagaagat attttaatat aggtgagttt tgtaaagttt aaacaaaatc tttatttaaa
    16861 taaaagaaac cccacttgtc tctggggttt ctgaaggcaa tgaaagtact cgactaatta
    16921 aagattccat gaattttttg gtgaaaatac tggtgaattc gtctgaatta atgagggcat
    16981 ctaaagcttt atacgtacgt gaagtaatta aaaatcgatt tataagagtt agcttgtttt
    17041 tcttaatagc ccacctaatc agtaaataca tatgtctgtt gaaatcttta cgtgttcatt
    17101 gataaaaagc tgactatatt cagtcagctt tttgtataat acattctagt atttatcggt
    17161 tccaaaatac atattctttc ctttaagttg gcatcgaaaa tattaccaat ttttcctttt
    17221 acaatggcaa caaataaaga aacatttaca acgacactta tttcgtttag aactccaatc
    17281 atcatcacaa tgacagtttt ctttagattc ccaccaatca tcattacaat gctttttctg
    17341 agaactccac caatcatcac aacaatgttt tttctgagaa ctccagcaat catttttcca
    17401 ggacatttat ttctacctcc tttcaatagt gttcatatta ttctatgttt taataaaaaa
    17461 tggcttgttt attaacctac tatttcatcc ttatatgata gagtgttttc tactcgatat
    17521 agagttcata caaactatgc taatttttaa gagatagtgg agagaactac tactagttat
    17581 ggtatttttt aataaacatt tgttgaagaa agcgttctga ttacaaataa tatcttattt
    17641 tcgagtacgc ttttttgaat gtatatttca caataacaaa ggaaaaatcc acaaataaag
    17701 tctatgtata tgtgagctaa tgggaaaatc tagtgcgttt ttaagaagcg tcttatttaa
    17761 aagaaaaaag atttgtttta gagaatggtg tctaaacatt aaatgaagta ggactaaatt
    17821 cacggcccct cattaaacaa gcttttaatt aggggaggtc tgtttttata atgaataatg
    17881 aaaagaaagt ttggtacaat ggtttgtttt tttcttttta tgtgtttgcc tcgtaccctt
    17941 ttaagctagt ggacatactt tactaataga aatgattagg gggtgaggta ttgggttctc
    18001 gatttaataa ttgtaaaaag aagtgtacat gtaaacagga tgattgttgg gaagtattcg
    18061 aagagtgtaa aaaagaacag catgagaaat gtgataattc ttgtgtacaa ggaattagag
    18121 atgaacttaa gaaattaatt aatcgaacag ttcaaattaa cacagaggga cgtacttatg
    18181 taggtactgt ttcgtctgta agttgtgatg tagttaagct tgcggctatt cctggatcgg
    18241 ttggagtaat tatttccatt tgcaaaattg aagcaatttt cccacctgtt acaacggtta
    18301 cggctgactt tgattttaat ggtattgatg tagcaaacaa ggcataatta tgctgctttt
    18361 ttgtaaagcc attcacatga atggctttat tttaatttca tataaaagga gaatatattc
    18421 tttatataga aataagtttg aggttataaa gcattatgta cgaaaggagc aaggaaatga
    18481 ttaaactaga aacctttaaa aaatctgatt ataaacaatt aataaattgg attaattccg
    18541 aagaatttct aatacaatgg tcaggtaatg ccttcacatt tcctttagac gaacagcaat
    18601 tagagaagta tatagaaagt gtaaatacac tcgctttcaa agtggtagat gaagagactt
    18661 cagacgttat tggtcatatt tcgcttgggc aaatagataa tattaacaag tccgctagaa
    18721 ttggaaaagt attagttggt aatacgaaaa tgagaggacg ttctatagga aaacatatga
    18781 tgaaagcagt acttcatatt gcttttgaca aattaaaact acatagagta actcttggtg
    18841 tgtatgattt taatacatcg gccatttcat gttacgaaaa aatagggttt gtaaaagaag
    18901 gcttattaag agagtcaaaa agggtaggag aaacgtattg gaatttatgg gaaatgagta
    18961 tgttagaata tgaatggaag aagtagcaac gatagtgatt tataattata ttatgttaac
    19021 aaaaggggat tggtgggtag tggataataa aacaaaaata atttcagttg cagctgtttc
    19081 agggggaggt aaaactacaa ttacagaaag attaaagcat gagtttaaaa actcaaaagc
    19141 tttatatttt gatagttata tatttgataa ctgtcctgct gatatttgta aatggattga
    19201 tgatggggcg aattatgacg agtgggtatt aacaccatta atttatgata ttgagcaact
    19261 tatacaaaat aatagcttag actatattat tatagattat ccttttgcat acttaaatag
    19321 tgagatgcga aaattcattg atgtaactat atttattgat acgcctttag atattgcgat
    19381 ggctagaagg attttgcgag attttaagga aggtacaata gatgaaatac ataatgactt
    19441 ggaacattac atgacatatg caagaaaagc ttatttagag gcaattcata ctgttaagcc
    19501 gaattcagat atcatattgg atggttcttt atctgtaagt gaaataatta atcacgctgt
    19561 agaggaactt ggccgaagag aagtgattat caatggttaa atgtataaca gatgctgtta
    19621 ggtggataat tgaagtaagg gagagataaa tgtgtacact ttatttcaat ataattggca
    19681 agtaagagat gattggttta agaggtgtga acaactttca gaggaagatt tactttgcaa
    19741 actggtggta ttttagaaac attatttcat attgtagatg tagagtatag ttggattagt
    19801 gctcttcaag gagaagaaga tagagaaccg cgatttaaag atattcaaaa agtgaaagcg
    19861 ttatctgatt tatataaacg agaacttgaa ggttttttgc agtcatggtc atctagccta
    19921 gaatgctagc acacttaaaa taagacgtat aaaaagttaa tcattgtgtg ctttgattat
    19981 ataatgtcgg cgaaataaat agtgtgaaag acagctatct tacaagtgtt tcatgtaacg
    20041 ttcatatact ttaatttttt ataattaatc aaatttgaat tttgtttgtt gttaagaaaa
    20101 ggtgagaaga aaataaaaaa agagggctaa ttggtattat cccctata
//
