LOCUS       NZ_NTSF01000031        40251 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS021634
            AFS021634_110_H4_Contig31_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTSF01000031
VERSION     NZ_NTSF01000031.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 136373)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 136373)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.88x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563165.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 02:22:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,903
            CDSs (total)                      :: 5,824
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 84 of 212
            Pseudo Genes (incomplete)         :: 133 of 212
            Pseudo Genes (internal stop)      :: 67 of 212
            Pseudo Genes (multiple problems)  :: 60 of 212
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:49:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 40251
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTSF01000031.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..40251
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..40251
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..40251
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[16669:20251](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(16670..20251)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            <1..213
                     /locus_tag="CN325_RS23595"
                     /old_locus_tag="CN325_23595"
     CDS             <1..213
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161137.1"
                     /locus_tag="CN325_RS23595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23595"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_141534886.1"
                     /transl_table=11
                     /translation="GNGSQGGNRVKGDSNSQEGNGSQGDNVKDNTKKQGDKLPNTATHY
                     PISILMGLSTFLIGMLLFIRRKNVK"
     gene            complement(330..1760)
                     /gene="proS"
                     /locus_tag="CN325_RS23600"
                     /old_locus_tag="CN325_23600"
     CDS             complement(330..1760)
                     /EC_number="6.1.1.15"
                     /GO_function="GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040954.1"
                     /locus_tag="CN325_RS23600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23600"
                     /product="proline--tRNA ligase"
                     /protein_id="WP_098391821.1"
                     /transl_table=11
                     /translation="MAKEQVQAITKMEEDFAQWYTDIVKKAELVDYSSVKGCMILRPYG
                     YALWENMQKVMDEKLKETGHENVYMPMFIPESLLQKEKDHVEGFAPEVAWVTHGGDEKL
                     AERLCVRPTSETLFCEHFSKIVQSYNDLPKLYNQWCSVVRWEKTTRPFLRTTEFLWQEG
                     HTIHETAEESQAETLNILNLYASFCEDYLAIPVIKGQKTEKEKFAGAKETYTIESLMHD
                     GKALQTGTSHNFGTNFSEAFDIKFLDRNGKWQYVHQTSWGVSTRMIGGLIMVHSDNNGL
                     VMPPKVAPVQVVIVPIAQHKEGVLAKATELQGHIQKVARVKIDASNKTPGWKFNEYEMK
                     GIPIRLEVGPKDIEKNQVVLVRRDTKEKEFVPMDQLEERIPALLEEIHIALFNKAKAFR
                     DENTYVATNFEEMKKIADEKQGFIKAMWCGELACEEKLKEEVGVSSRCMPFEQEHLAEE
                     CICCGKEAKQMVYWGKAY"
     misc_binding    complement(1808..2014)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     misc_feature    1848..1864
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     misc_feature    complement(1848..1864)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            complement(2108..2401)
                     /locus_tag="CN325_RS23605"
                     /old_locus_tag="CN325_23605"
     CDS             complement(2108..2401)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383847.1"
                     /locus_tag="CN325_RS23605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23605"
                     /product="YesK-like family protein"
                     /protein_id="WP_141534887.1"
                     /transl_table=11
                     /translation="MDWLDGFGIFYSIGGITILLVFAISYLLKKRFPDKQFDIIFALIV
                     ILLCLASFPVTMMVIGGWEGMGYGFIGFFVLLGTLIGMIAHQLVKISRKSYV"
     misc_feature    2448..2462
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     gene            2555..3868
                     /locus_tag="CN325_RS23610"
                     /old_locus_tag="CN325_23610"
     CDS             2555..3868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017673773.1"
                     /locus_tag="CN325_RS23610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23610"
                     /product="ectonucleotide pyrophosphatase/phosphodiesterase"
                     /protein_id="WP_000356442.1"
                     /transl_table=11
                     /translation="MDKALTNRVIILSFDCLSALDFPILQKLPHFQSLIKKGTVVEKVE
                     PIYPSVTYPSHSTIVTGNYPNKHGVVSNTLLQPGRESPDWHWYRKSIKGTTLYDEARKA
                     NLTTAALLWPVTGRANIDYNLPEIFPNRPWQNQVLVSLFSGSPLYQLDLNRRFGHIRNG
                     LSQPELDDFVLASAVHTIQTKKPNVMFVHFTDLDTQRHYHGFESNETIAAIHRHDERLG
                     KIIQTLKDSDLYEESTIIALGDHSALSENKAIQLNVLFQQKGLVSINKKGLLVDWKAYC
                     QSCDGSAYVYVKDKNDTDTIREVQLLLEELLQNKQNGIEFILHDEAAKDCGADGNCLFM
                     LEAQEGYYFTENYTGDFIKEITEKDVTPSKKYTFGTHGYSPTKPNYETIFIAAGKGIKT
                     GVTVPYMRLIDEGPTIARLLGLHLGETDGSIVEDLLQL"
     gene            3977..5260
                     /locus_tag="CN325_RS23615"
                     /old_locus_tag="CN325_23615"
     CDS             3977..5260
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016117108.1"
                     /locus_tag="CN325_RS23615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23615"
                     /product="MFS transporter"
                     /protein_id="WP_098391823.1"
                     /transl_table=11
                     /translation="MEEMSRQEKSWILYDWANSVYSLVITTALFPIYFKAAAKEAGLSG
                     ATSTAYWGYANSFATLLISILAPILGTVADYKGFKKRFFTFFFGLGIVFTSMLAVVPTS
                     QWYLLLGCYMLALVGFAGANIFYDAFLVDVTSEDRMDRISTRGFALGYIGSTIPFIGCI
                     ALIILAQKGTIPLSVGIASQISFAITALWWGLFTIPMLKNVEQTHYIERHPRPIKMSFK
                     RLADTFKNIKEYKTVFMFLIAYFFYIDGVDTIITMSTAYGTDLGISATNLLIILFVTQI
                     VACPFALLYGKLSETFTGKKMLYVGIIIYIIICTYAYFLKTTLDFWILAMLVATSQGGI
                     QALSRSYFAKLVPKESANEFFGFYNIFGKFAAIMGPVLVGVTTQLTGKTNAGVLSIIVL
                     FIIGGFLLTRVPENNTSVTPPSPKTKTL"
     gene            complement(5330..5581)
                     /locus_tag="CN325_RS23620"
                     /old_locus_tag="CN325_23620"
     CDS             complement(5330..5581)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011732448.1"
                     /locus_tag="CN325_RS23620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23620"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_002023181.1"
                     /transl_table=11
                     /translation="MSQLYTDVVKTILQVRSNGVKNQIYELRTENNISQGALADKCKVS
                     RQTINAIENNKYDPSLALAFRLAEVLGTTVDKLFLYKQ"
     gene            complement(5638..6870)
                     /locus_tag="CN325_RS23625"
                     /old_locus_tag="CN325_23625"
     CDS             complement(5638..6870)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992541.1"
                     /locus_tag="CN325_RS23625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23625"
                     /product="MFS transporter"
                     /protein_id="WP_098391824.1"
                     /transl_table=11
                     /translation="MKALFKNRAFMLVMASDILQQFAIWIRNMALLYFIMERTNNDPVS
                     VSLLSVMEYAPIFIFSFIGGALADRWNPKRTMVAGDVLSVLSIIGIVLLLKLDYWQAIF
                     FATLISAIVGQFSQPSSSRIFKRYVKEEQVANAIAFNQTLQSLFLIFGPVVGSLVYTQL
                     GLFTSLYSLIILFLLSAIILSFLPKWVEKEQVARDSLKNDIKEGWKYVLHTKNLRMITI
                     TFTIMGLAVGLTNPLEVFLVIERLGMEKEAVQYLAAADGIGMLIGGIVAAVFASKVNPK
                     KMFVFGMSILAMSFLVEGLSTSFWITSFMRFGTGICLACVNIVVGTLMIQLVPENMVGR
                     VNGTILPLFMGAMLIGTSLAGGLKELTSLVTVFCIAMALILLAIGPVLRMQIKKEDVAN
                     KEALTNSLASK"
     gene            complement(6937..7518)
                     /locus_tag="CN325_RS23630"
                     /old_locus_tag="CN325_23630"
     CDS             complement(6937..7518)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001254438.1"
                     /locus_tag="CN325_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23630"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_098391825.1"
                     /transl_table=11
                     /translation="MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIY
                     YHFKSKEELFLFVVKQHTYDWVEKWNEKEKLYSTSTEKLYGLAEYHVEDIQQPISNAIE
                     EFSMSQIVSKEILDELLALTRESYVMFEKLIEAGIQSGEFREDNARDLMYIVNGLLSGL
                     GVLYYELDYKELKRIYKKAIDVLLKGMAAE"
     gene            complement(7599..7742)
                     /locus_tag="CN325_RS23635"
                     /old_locus_tag="CN325_23635"
     CDS             complement(7599..7742)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817979.1"
                     /locus_tag="CN325_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23635"
                     /product="hypothetical protein"
                     /protein_id="WP_000817981.1"
                     /transl_table=11
                     /translation="MKREPKVKNKGKVVLFLLAAGGVFLVKLAFKFGTIHMIRTWFEST
                     FS"
     misc_feature    complement(7772..7785)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.13"
                     /tool="antismash"
     misc_feature    7776..7789
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.91"
                     /tool="antismash"
     misc_feature    7821..7834
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.71"
                     /tool="antismash"
     gene            complement(7868..8113)
                     /locus_tag="CN325_RS23640"
                     /old_locus_tag="CN325_23640"
     CDS             complement(7868..8113)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394350.1"
                     /locus_tag="CN325_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23640"
                     /product="hypothetical protein"
                     /protein_id="WP_000394364.1"
                     /transl_table=11
                     /translation="MEFIIVILLFVVVGIIVTAVRSNKKKVNLTKQNNIHNSSNSSSPL
                     FFFAGSDNDSSHDGGSHDCGGSFGGDSGGSCGGGGD"
     gene            complement(8127..8441)
                     /locus_tag="CN325_RS23645"
                     /old_locus_tag="CN325_23645"
     CDS             complement(8127..8441)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206512.1"
                     /locus_tag="CN325_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23645"
                     /product="thioredoxin family protein"
                     /protein_id="WP_064532164.1"
                     /transl_table=11
                     /translation="MTTFKTIEELATYIEEQQLVLLFIKTENCGVCDVMLRKVNCVLEN
                     YDYVEKIEILLQDMQEIAGRYAVFTGPTILLFYNGKEILRESRFISLENLERTIQLFEE
                     "
     gene            complement(8452..8823)
                     /locus_tag="CN325_RS23650"
                     /old_locus_tag="CN325_23650"
     CDS             complement(8452..8823)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002010200.1"
                     /locus_tag="CN325_RS23650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23650"
                     /product="DUF1992 domain-containing protein"
                     /protein_id="WP_098391826.1"
                     /transl_table=11
                     /translation="MDVFLNIAEEKIRQAIRNGDLDYLPGKGKPLQLEDISMVPPELRM
                     SYKILKNAGMIPTEMELQKDILKIEDLIACCYDEEERKKLREDLTVKTLRFQQVMEKRK
                     IKDSSAFRMYQDKVFRKLR"
     gene            9196..11220
                     /locus_tag="CN325_RS23655"
                     /old_locus_tag="CN325_23655"
     CDS             9196..11220
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257491.1"
                     /locus_tag="CN325_RS23655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23655"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_071714726.1"
                     /transl_table=11
                     /translation="MRSQKFTLLLLSLLLFLPLFLTNFITPNLALADSPKQSQKIVGYF
                     PSWGVYGRNYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQTWNCKESGVP
                     LQNKEVPNGTLVLGEPWADVTKSYPGSGTTWEDCDKYARCGNFGELKRLKAKYPHLKTI
                     ISVGGWTWSNRFSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWEYPGVETIPGGSYR
                     PEDKQNFTLLLQDVRNALNKAGAEDGKQYLLTIASGASQRYADHTELKKISQILDWINI
                     MTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEGVPVDKLVLGVPFYG
                     RGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGDLAANYVNKNGFVR
                     YWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGDCRTSPKYS
                     CSGPKLLDTLVKELLGGPISQKDTEPPTNVKNIVVTNKNSSSVQLSWTASTDNVGVTEY
                     EITAGEEKWSATTNSITIKNLKPNTEYTFSVIAKDAAGNKSQPTALTVKTDEANTTPPD
                     GNGTATFSVTSNWGSGYNFSIIIKNNGTTPIKNWKLEFDYSGNLTQVWDSKISSKTNNH
                     YVITNAGWNGEIPPGGSITIGGAGTGNPAELLNAVISEN"
     gene            complement(11667..13211)
                     /locus_tag="CN325_RS23660"
                     /old_locus_tag="CN325_23660"
     CDS             complement(11667..13211)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716351.1"
                     /locus_tag="CN325_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23660"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_098391827.1"
                     /transl_table=11
                     /translation="MSILTVENLSHSYGEKTILYNACFRLLKGEHVGLVGKNGIGKSTL
                     LRILTGELIHDDGNIEWFPHVKVGFLQQHIDLQEGITIEGYLQSAFSNLYAIEYEMLKI
                     AEEMAEAVEVEKLLVRYGELQTILENSNFYQIHTEIEEVAIGLGLFEIGLEKDVSKLSG
                     GQRTKLLLGKLLLEKADVLLLDEPTNYLDTAHIEWLQSYLKLYEKAYIIISHDEVFLNN
                     ITNVIYHLEERKVKRYVGDYEKFLQSYQVQRKQLQSAYVKQQKEIAQLETFIQKNKIRK
                     AKQAKSREKVLEKMQRVEKVNNIPRSRFAFTVYNEPVSRILQAEKLRVGYSEPLFPDLN
                     LQVKKGEKIAVVGHNGIGKTTMLKTLLGQIKPLSGSIFVGERVNPAYFAQEEFASEITP
                     LEKVWAEQPDMTKKEVRQALAKCGLKEEHVLKPIRLLSGGEQTKVRLCELIVTKSNVLI
                     LDEPTNHLDVETKMALQEALQQYKGTVLIVSHEPSFYESWITKVWNIEDWNAEQYE"
     gene            complement(13608..14357)
                     /locus_tag="CN325_RS23665"
                     /old_locus_tag="CN325_23665"
     CDS             complement(13608..14357)
                     /EC_number="7.6.2.7"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000016061.1"
                     /locus_tag="CN325_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23665"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098391828.1"
                     /transl_table=11
                     /translation="MSGLQIKNIVKSFDGKNVLENISACIQEGEFVSFVGPSGCGKSTL
                     LNMIANVEKPTSGNVMYKDKQVQEQDVVSYMPQQDLLLPWRSALQNIVLPLEIEGKPKK
                     QRLTEGMEALKQFELDEYADHYPDELSGGMRQRISFLRTYLCEKPIMLLDEPFGKLDAF
                     TKMEVHSWLLNSWHQEKQTIVMVTHDLDEAILLSDRVFILSQRPASIVGEVQVKLPRPR
                     TMDMLTSLELKKDKEEILSVLAPYMKK"
     gene            complement(14354..15352)
                     /locus_tag="CN325_RS23670"
                     /old_locus_tag="CN325_23670"
     CDS             complement(14354..15352)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002091223.1"
                     /locus_tag="CN325_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23670"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_098391829.1"
                     /transl_table=11
                     /translation="MKKGLKVMLAALVAVGVAGCNPAKKEESTSKDQKVKVVLDWFPNT
                     NHTGLYVAQTKDYYKKQGLDVEIIQPGDNVTAEQMIASGKADFAISAQENVTLARVEGI
                     PVVSVGAIIQHNTSAFASLKKDNMTSPKDFEGKRYGGWGGPAEEATLKTIMDKHQADFN
                     KVEKIILGQTDFFKSIGRDADFEWIYYGWDGIEAKRQGKELNTIMVKDLDPALDFYSPV
                     IITSEKHTKQDKDFVKKFMSATTEGYNFAIKEPKEAADILIKAVPDVNKDLVQESQKWL
                     STKYQDDAKAWGVQKEEIWTNYMNFLYDNKVIKKKIDVKDAFTNEFLPSEK"
     gene            complement(15349..16122)
                     /locus_tag="CN325_RS23675"
                     /old_locus_tag="CN325_23675"
     CDS             complement(15349..16122)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016107454.1"
                     /locus_tag="CN325_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23675"
                     /product="ABC transporter permease"
                     /protein_id="WP_001057164.1"
                     /transl_table=11
                     /translation="MNMQNQKQSKLITTIWLILLIAIWEGSVSLFKIEPWILPKPSAIV
                     QELIGMKDLLLPNTMQTLQEVIIGLFFAILLGTSIAIIMDVIPLFRILINPLLVISQTI
                     PIVVLAPLFIIWFGYGMLPKVMVVILVCFFPIALSILEGFQTVDKNMLKLLQTMKATKW
                     QVYQKVKFPAVLPYFFSGLKIAVTYSVMGAIIGEWLGASEGLGVMLTRATKSFLTARVF
                     GVAAIIVIVTLCLYFIVEFMARITAPWIYRKDGRK"
     gene            complement(16094..16414)
                     /locus_tag="CN325_RS23680"
                     /old_locus_tag="CN325_23680"
     CDS             complement(16094..16414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082896.1"
                     /locus_tag="CN325_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23680"
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="WP_000082906.1"
                     /transl_table=11
                     /translation="MSQQVTMSFSVVPQAKTKDVYSVVDKAIEVVQQSGVRYEVGAMET
                     TLEGELDVLLDVVKRAQQACVDAGAEEVITSIKIHYRPSTGVTIDEKVWKYRDEYAKPE
                     AI"
     misc_feature    16390..16402
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    16494..16510
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 24.98"
                     /tool="antismash"
     regulatory      complement(16515..16617)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(16670..20251)
                     /locus_tag="CN325_RS23685"
                     /old_locus_tag="CN325_23685"
     CDS             complement(16670..20251)
                     /NRPS_PKS="Domain: AMP-binding (225-621). E-value:
                     6.4e-108. Score: 352.9. Matches aSDomain:
                     nrpspksdomains_CN325_RS23685_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (730-794). E-value: 4.2e-19. Score:
                     60.5. Matches aSDomain: nrpspksdomains_CN325_RS23685_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (833-1071). E-value:
                     1.7e-54. Score: 176.5. Matches aSDomain:
                     nrpspksdomains_CN325_RS23685_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761477.1"
                     /locus_tag="CN325_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23685"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_098391830.1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-115, bitscore:
                     379.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.2e-10, bitscore:
                     32.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.4e-54, bitscore:
                     176.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLAISYNEMVKEFLGKVEGSIKIPKDVQGTELRIKRKTELFLNL
                     THIVDLIGATATWLYHISKEKHIVVLYHVRGSLFPITIEVSNFLSYESLNLQIEEQLEQ
                     IKEMNEEEIEEFQNGNTLYEMSPIIIGETYYQLQDTNTLQFVFSKNMQSVEIIFNSVNW
                     KETTITRYAQQIQGVLIGTSQNKNNYIKNFNIITEAEMALYSQVNDTTAVYPEKSIVDM
                     FYNTVTQFPNRIALSSREGTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTV
                     VSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILMKETPITCDGVQTVSMYDSET
                     CEDIDVKLSIHCDDVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMQKQYELTEEDVFAQ
                     FPSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQ
                     VATYLAEGDIYKLASLKRIAIGGEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTT
                     YKIPSQLNEDVASIPIGKPCANYQVMILDENMNLCPIGVPGELYIDSVGLAKGYFNKPN
                     KTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLHRKDDQVKIRGHRIELGEIQSKIS
                     QNHNIKENAVFAKKSKEGSQYLIAFYTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINE
                     LPLTPNKKIDVKKLAQLEEKYEAVRLQEYVAPSNKAEKQIANAWAEVLGISKVGVHDDF
                     FTIGGHSLKVLRVLTLLKEDFSHLTIQDFFKERTIYGLARIEREVKVEKEEVFREYKVI
                     HEPDTITYANVLEETQISNVFLTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRI
                     INTLTGYFSDICEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFG
                     DVKQFENINVQGTSRMLALAEKGATFHFISTIGIPLELAVDQWDTYMKTGDFNYSVDLE
                     NVYSNSKLQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFYRLIKTMLL
                     IGKAPNVKWKVDFTPIDFASKSIVSYLQDAQIVGETLHICHPHQIEFEQFIQLIGECGY
                     NLEMVPLSEYVNTGLELAKRNEVIAELIASQVARDGAQQSEIVMGTRRTNEWIKKKELI
                     VPTINKEFIQQLLAHGEKVGYFPKIMK"
     aSDomain        complement(17039..17752)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN325_RS23685_NAD_binding_4.1"
                     /evalue="1.70E-54"
                     /label="CN325_RS23685_NAD_binding_4.1"
                     /locus_tag="CN325_RS23685"
                     /protein_end="1071"
                     /protein_start="833"
                     /score="176.5"
                     /tool="antismash"
                     /translation="LTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRIINTLTGY
                     FSDICEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFEN
                     INVQGTSRMLALAEKGATFHFISTIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSK
                     LQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFYRLIKTMLLIGKAPNV
                     KWKVDFTPIDFASKSI"
     aSModule        complement(17039..19576)
                     /complete
                     /domains="nrpspksdomains_CN325_RS23685_AMP-binding.1"
                     /domains="nrpspksdomains_CN325_RS23685_PCP.1"
                     /domains="nrpspksdomains_CN325_RS23685_NAD_binding_4.1"
                     /locus_tags="CN325_RS23685"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(17870..18061)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN325_RS23685_PCP.1"
                     /evalue="4.20E-19"
                     /label="CN325_RS23685_PCP.1"
                     /locus_tag="CN325_RS23685"
                     /protein_end="794"
                     /protein_start="730"
                     /score="60.5"
                     /tool="antismash"
                     /translation="EKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFS
                     HLTIQDFFKERTIYGLARI"
     CDS_motif       complement(18359..18424)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS23685_0005"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="CN325_RS23685"
                     /protein_end="631"
                     /protein_start="609"
                     /score="36.0"
                     /tool="antismash"
                     /translation="FLHRKDDQVKIRGHRIELGEIQ"
     aSDomain        complement(18389..19576)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CN325_RS23685_AMP-binding.1"
                     /evalue="6.40E-108"
                     /label="CN325_RS23685_AMP-binding.1"
                     /locus_tag="CN325_RS23685"
                     /protein_end="621"
                     /protein_start="225"
                     /score="352.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="TVTQFPNRIALSSREGTLTYEELNKKSNQIAHMLIKNGVQLGDYV
                     GIFMKRSIDTVVSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILMKETPITCDG
                     VQTVSMYDSETCEDIDVKLSIHCDDVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMQKQ
                     YELTEEDVFAQFPSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFANAIYKVKATS
                     ILALATIFVRQVATYLAEGDIYKLASLKRIAIGGEMLPVEVIKLWRERIGTNVEIHNVY
                     GPTECTVVTTTYKIPSQLNEDVASIPIGKPCANYQVMILDENMNLCPIGVPGELYIDSV
                     GLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLHRKDDQVKIR"
     CDS_motif       complement(18506..18595)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS23685_0004"
                     /evalue="4.10E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="CN325_RS23685"
                     /protein_end="582"
                     /protein_start="552"
                     /score="35.1"
                     /tool="antismash"
                     /translation="PIGVPGELYIDSVGLAKGYFNKPNKTIEAF"
     CDS_motif       complement(18707..18736)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS23685_0003"
                     /evalue="3.90E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="CN325_RS23685"
                     /protein_end="515"
                     /protein_start="505"
                     /score="9.9"
                     /tool="antismash"
                     /translation="YGPTECTVVT"
     CDS_motif       complement(19127..19186)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS23685_0002"
                     /evalue="5.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="CN325_RS23685"
                     /protein_end="375"
                     /protein_start="355"
                     /score="28.2"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGNPKGTMLAH"
     CDS_motif       complement(19358..19396)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CN325_RS23685_0001"
                     /evalue="6.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="CN325_RS23685"
                     /protein_end="298"
                     /protein_start="285"
                     /score="19.2"
                     /tool="antismash"
                     /translation="AILKAGAAYVPID"
     misc_feature    20295..20310
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    20323..20337
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            complement(20389..22131)
                     /locus_tag="CN325_RS23690"
                     /old_locus_tag="CN325_23690"
     CDS             complement(20389..22131)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016121779.1"
                     /locus_tag="CN325_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23690"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_000761081.1"
                     /transl_table=11
                     /translation="MKKYWHKLSFLQKNVLLTVLVILTLVGSMGALSFNMFQNSMMSLF
                     ERQSIETGEIVLKKLDVELVRDMAKDPTAEKVKKEKLTEKLDEVSKELKSVGQTYVTGA
                     KPNEKRELQLVGLTTELTNAFPIKPGDYYEQPAHWMKAYDKVIDTKKAQMTEVYEDEIG
                     SWVTILEPITDGENNIVAIIAADLDASIVPITKEKFMIQGLLFIIISLAIATITQFFIV
                     RHSLAPLKDLREGLRKIGEGDLSIKLKERPDDIGIINVYFNNTIEKFKGIIDKVRQTAE
                     QVSSSSQELSASTEENSMAVQEIASSIEGLRVGAQSQKTSVQQCLGIVHGMEDKVEEIT
                     GAAKQVAVASEGMEQHSIEGNEVIGQIINQMSLIQNAVQDLSSIIYSLETRSKEISDIV
                     TVITGISNQTNLLALNASIEASRAGAAGRGFAVVADEVRKLAEQTEASAKDIAKLIGET
                     QAETEDAVVSMQKGSKEVETGISLVQSSGDFFEKISKSAQSVTDQVKAVSGNSSDILQN
                     SQNIVQVVNELSHIANTYANSSSNVEESMKEQEISVQDIAELATSLSWLSQELQELIGE
                     FKSE"
     misc_feature    complement(22188..22206)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 25.72"
                     /tool="antismash"
     misc_feature    complement(22190..22204)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 25.16"
                     /tool="antismash"
     misc_feature    complement(22191..22206)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.99"
                     /tool="antismash"
     misc_feature    complement(22243..22257)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.11"
                     /tool="antismash"
     regulatory      complement(22265..22349)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            22632..23945
                     /locus_tag="CN325_RS23695"
                     /old_locus_tag="CN325_23695"
     CDS             22632..23945
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015556 - C4-dicarboxylate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498692.1"
                     /locus_tag="CN325_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23695"
                     /product="anaerobic C4-dicarboxylate transporter"
                     /protein_id="WP_000498704.1"
                     /transl_table=11
                     /translation="MFWLQFLTLLLCIFIGARLGGVGLGVMGGVGMAILVFVFHLQPTA
                     PPIDVMLMILAVITAAGALQAAGGMDYLVHLAEKALRKNPKRITFFAPIVTYLFTLCAG
                     TGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKI
                     TLLDILKVSIPSTFIACMLAAFVASKMGKELNEDPEYLKRLKEGMIPKLEEKKEFVGVK
                     GAKLSVILFLVGTFLVVLLGSFEALRPGWIVDGKLARLSMPNTIEMVMLTIAALIIIFC
                     KPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIA
                     LFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDR
                     TGTTGIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF"
     gene            complement(24062..24721)
                     /gene="thiE"
                     /locus_tag="CN325_RS23700"
                     /old_locus_tag="CN325_23700"
     CDS             complement(24062..24721)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083676.1"
                     /locus_tag="CN325_RS23700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23700"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_141534888.1"
                     /transl_table=11
                     /translation="MMRIETKKMSKLLQVYFIMGSNNCTRDPLAVLKEALDGGVTLFQF
                     REKGEGSLIGEDRVRFAKELQTLCKEYSVPFIVNDDVELAIELDADGVHVGQDDEGITS
                     VREKMGDKIIGVSAHTIEEARFGIEHGADYLGVGPIFPTSTKKDTKAVQGTKGLAYFRE
                     QGITVPIVGIGGITVENTAAVIEAGADGVSVISAISLAESAYESTRKLAEEVKRSL"
     gene            complement(24736..25545)
                     /gene="thiM"
                     /locus_tag="CN325_RS23705"
                     /old_locus_tag="CN325_23705"
     CDS             complement(24736..25545)
                     /EC_number="2.7.1.50"
                     /GO_function="GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125363.1"
                     /locus_tag="CN325_RS23705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23705"
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="WP_098391832.1"
                     /transl_table=11
                     /translation="MNMKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVM
                     AYAKEEVAEMASIAGALVLNMGTLRPEEVEAMLLAGKSANANNVPVLFDPVGAGATSYR
                     TEVARHIPAEIDLAIIRGNAAEIANVINEKWEIKGVDAGTGNGNVVSIARQAADELNTV
                     AVITGKEDVVTDGERTIVIRNGHPILTKVTGTGCLLTSVIGAFVAVEKDYVKAAVAALT
                     FYGVASELAAAKTVEKGPGNFQIEFLNQLANTTAGDIEKYGKIEELE"
     regulatory      complement(25618..25730)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(25757..25773)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.78"
                     /tool="antismash"
     misc_feature    complement(25880..25899)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.33"
                     /tool="antismash"
     gene            26092..28281
                     /gene="topB"
                     /locus_tag="CN325_RS23710"
                     /old_locus_tag="CN325_23710"
     CDS             26092..28281
                     /EC_number="5.6.2.1"
                     /codon_start=1
                     /gene="topB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140209.1"
                     /locus_tag="CN325_RS23710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23710"
                     /product="DNA topoisomerase III"
                     /protein_id="WP_098391833.1"
                     /transl_table=11
                     /translation="MSKSVVIAEKPSVARDIARVLKCDKKGNGYLEGSKYIVTWALGHL
                     VTLADPESYDVKYKKWNLEDLPMLPERLKLTVIKQTGKQFNAVKSQLLRKDVNEIIVAT
                     DAGREGELVARWIIDKVKLNKPIKRLWISSVTDKAIKDGFANLKPGKAYDNLYASAVAR
                     SEADWYIGLNATRALTTRFNAQLNCGRVQTPTVAMIASREDEIKNFKAQTYYGIEAQTM
                     EKLKLTWQDANGNSRSFNKEKIDGIVKSLDKQHATVVEIDKKQKKSFSPGLYDLTELQR
                     DANKKFGYSAKETLNIMQKLYEQHKVLTYPRTDSRYISSDIVGTLPERLKACGVGEYRP
                     FAHKVLQKPIKPNKSFVDDSKVSDHHAIIPTEGYVNFSAFTDKERKIYDLVVKRFLAVL
                     FPAFEYEQLTLRTKVGSETFIARGKTILHAGWKEVYENRFEDDDVTDDVKEQLLPHIEK
                     GDTLTVKLLMQTSGQTKAPARFNEATLLSAMENPTKYMDTQNKQLADTLKSTGGLGTVA
                     TRADIIDKLFNSFLIEKRGKDIHITSKGRQLLDLVPEELKSPTLTGEWEQKLEAIAKGK
                     LKKEVFISEMKNYTKEIVSEIKSSDKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQ
                     DRECGHRKNVSRTTNARCPQCKKKLELRGEGAGQIFACKCGYREKLSTFQERRKKESGN
                     KADKRDVQKYMKQQKKEEEPLNNPFADALKKLKFD"
     gene            complement(28322..31297)
                     /locus_tag="CN325_RS23715"
                     /old_locus_tag="CN325_23715"
     CDS             complement(28322..31297)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810091.1"
                     /locus_tag="CN325_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23715"
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="WP_000810094.1"
                     /transl_table=11
                     /translation="MKQIWRIYKTDLRNVAKHWAAIVIVLGLMILPSLYAWFNIKASWD
                     PYGNTKEVPIAVSNQDAGSNLRGKDINIGKEIVDSLKKNKNLGWKFVDEKQAIYGVERG
                     DYYASITIPKDFSEKIATVLDENPKKPELDYYVNEKVNAIAPKITAKGASGITEEISKN
                     FVKTANGEIFKIFNDLGIDLETNLPSIEKVKDLVFKLEAQFPEMNTLMDKALDDATRAE
                     DVVKVAQKELPVVESVMNDGQEALGNLDKFFARNDETLQRAPGTIKNNLMVMQKGLDGA
                     AAITDFLKNPSLDFNLALPDPAKFPVLPNITLPQIPQIPEIPALPQVNGEGYKNVAKNI
                     DQTVNNVFNSTRVGTAYVKSVMDGLQNKGVDPAVAQKNVQDASKLLQERIDSVSYLIDF
                     FTTFKEAASTDFGKQFFGNRVESLTVLKNSMVDANNRVKHVGDLISSGQEVKQDVRDAV
                     NQKLDAVNNLVNQAEKDYNTNFVADFEKAVSTAEQLKNKAENVKEDAQQLRGNLNQDIK
                     KANELVNQTNEALDNGREKYDKAVNDYSRLKTELEKAREDLSNKGVNGLDSTKVALNDL
                     NGQFKASWNLVNDMIPVLESTNKVLADVNSDKNLNGTISKLNKAKDGLQKGMDLTDKGI
                     DAINKGQKPAADVIESINQVSKSVSGQIGDILAKYDSEITPNFNAAIARTKEMSKNTSQ
                     ILKEADKKLPDVKKLLEDSSKGLVDGKKKLADIKAEMPATEKKIKELADKIRDFESEED
                     LKDIIRLLKNDVEKQSDYFANPVNLKENKLFAMPNYGSAMSPFYTVLALWVGALLMVSL
                     LTVEVHEEGANYKSHEIYFGRLLTFLTIGLSQAFIVSMGDIFLLGTYVVDKFWFVLFSL
                     FIGGVFVCIVYSLVSIFGNVGKSMAIILLVLQVAGSGGTFPIQMTPAFFQAIYPFLPFT
                     YAISAIRETVGGMLWDIVTRDLLVLSAFVVVMIVAALLLKTPINKSSEKFVENAKGSKI
                     IH"
     misc_feature    31346..31358
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: strong, score: 25.04"
                     /tool="antismash"
     gene            complement(31603..32394)
                     /locus_tag="CN325_RS23720"
                     /old_locus_tag="CN325_23720"
     CDS             complement(31603..32394)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016121527.1"
                     /locus_tag="CN325_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23720"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_098391834.1"
                     /transl_table=11
                     /translation="MKLLTLNCHSWQEENQIEKIQYLAKVIQEEEYDVIALQEVSQSIQ
                     AENVCGNKKEDNFGLLLLEELKALHVKDYNITWDFSHIGYDVYEEGLAIITKHNIIKED
                     TFFISENEDTTYWKTRKIVSTTIAYNGKDITFYSCHLGWWNDEEESFKGQVDRLMERVD
                     SNKLAFLMGDFNNNARLKGEGYEYMMQKGLYDTYELAIEKDEGTTVQGEIAGWDENKHN
                     LRIDLILCNQSKKVHSSKVIFNGTNRNVISDHFGVEVQLDI"
     gene            complement(32399..34036)
                     /locus_tag="CN325_RS23725"
                     /old_locus_tag="CN325_23725"
     CDS             complement(32399..34036)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002151611.1"
                     /locus_tag="CN325_RS23725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23725"
                     /product="PTS transporter subunit IIBC"
                     /protein_id="WP_098391835.1"
                     /transl_table=11
                     /translation="MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNA
                     VHTIARVMEDIGWAIITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGV
                     NAQMLADSKATVSSVIAGDLIVKDYFTSVLGAPALNMGVFVGIITGFLGANLYNKYYNY
                     NKLPQALAFFNGKRFVPFVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVV
                     APFVYGTLERLLLPFGLHHMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITD
                     LNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMGIAFAMFRNVDKEKRAKYKPM
                     FLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELI
                     TRTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEAS
                     EGTGNVQDGSLATKVIDLLGGKENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGL
                     IVKDKGVQAVYGPKADVLKSDIQDMLGA"
     gene            complement(34242..35906)
                     /locus_tag="CN325_RS23730"
                     /old_locus_tag="CN325_23730"
     CDS             complement(34242..35906)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754571.1"
                     /locus_tag="CN325_RS23730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23730"
                     /product="alpha-glucosidase"
                     /protein_id="WP_098391836.1"
                     /sec_met_domain="Alpha-amylase (E-value: 3.1e-104,
                     bitscore: 341.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTWWKEAVAYQIYPRSFMDSNGDGIGDLQGIIAKLDYLKDLGI
                     DVIWICPMYKSPNDDNGYDISDYQDIMNEFGTMADFDALLDEVHKRDMKLIIDLVINHT
                     SDEHPWFIESRSSKDNPKRDWYIWHDGKDGAEPNNWESIFNGSAWEYDEETEQYYLHLF
                     SRKQPDLNWENKEVREVLYDTVNWWLDKGIDGFRVDAISHIKKEEGLKDMPNPKELKYV
                     PSFDKHMNVKGIQPLLEELKENTFSKYDIMTVGEANGVKIEDAELWVGEEQGKFNMVFQ
                     FEHLSLWDAEKKKDLDVVGLKKVLTKWQKGLENKGWNALYIENHDKPRIVSTWGDDKQY
                     WRESATALGAMYFFMHGTPFIYQGQEIGMTNVQLPNIEDYDDVAIKNLYREKIAEGVPH
                     QDMMEIIWASCRDNSRTPMQWNDEMNAGFTTSTPWFSMNPNYKEINVEKQKNEEKSIFN
                     FYKKMIALKKEHDVLNYGTYDLLLEDDPQIYAYTRTLQDEKVIVISNISKEEAVYNEDS
                     FALERKRLLLNNYEVVEHEEVKTIALKPYETRVYRIS"
     misc_feature    35946..35957
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.81"
                     /tool="antismash"
     misc_feature    complement(35958..35975)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.69"
                     /tool="antismash"
     gene            36152..37486
                     /locus_tag="CN325_RS23735"
                     /old_locus_tag="CN325_23735"
     CDS             36152..37486
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083682.1"
                     /locus_tag="CN325_RS23735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23735"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_098391837.1"
                     /transl_table=11
                     /translation="MKQTKLTGRIVVPTDSDYDVARMNLNLSIPKLPCIIVFCQNNKDV
                     CNALKWARERHIPFRLRSGRHSYENFSLLNRGLIIDVSEMHRITVNTEKLTATIEAGAN
                     LGTVYKELWNYGVTIPAGTSASVGIVGLALGGGIGMLSRLFGLTCDQLMEVEMIQACGK
                     FGAKLLRANEQENSNLFWACRGGGGGNFGIVTSLTFRVHPIKNVSIFSITWEWEDFIAA
                     FQAWQNWAPYIDERLTSSIELFAKQRNKIEAQGEFVGSPSELHSLLSPLLETGSPSLFI
                     EEVPYIKAVEFFNGGNIPENFKRSGSYVYKPIPLKGIQIMQYFLSHAPNKDASIWHQSL
                     IGAVENISPNETAYFHRKAIIAQEYITSWKCDDEENRNIRWVKDLRESLDPYTLGDYVN
                     WPDIDIKNWQTSYYGSNFHRLRKVKTMYDPCDVFHFQQSIPLFHT"
     gene            complement(37610..38293)
                     /locus_tag="CN325_RS23740"
                     /old_locus_tag="CN325_23740"
     CDS             complement(37610..38293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125360.1"
                     /locus_tag="CN325_RS23740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23740"
                     /product="ABC transporter permease"
                     /protein_id="WP_098391838.1"
                     /transl_table=11
                     /translation="MIRIEYDRLVAICYSIGVLLLLKIPNDNELIGEKLFNVYKVPIHT
                     YVYMDYKVSNILIVSFILHVIAFILFLKWLGKKESSTFRKMNKIKVVGISILIVMMPFI
                     LNTILQTLNKTWYYAGKTGVEAIEYKKEDSQCRMEENGEGIESKCIVTLKNYRNHSQAL
                     EVVLYDNANENSKSYPVPKPVYLQKHETKQFEFQVPVSYNRGMEKDKVPNIKLHSLHEN
                     DTKYN"
     gene            complement(38450..39139)
                     /locus_tag="CN325_RS23745"
                     /old_locus_tag="CN325_23745"
     CDS             complement(38450..39139)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081904.1"
                     /locus_tag="CN325_RS23745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_23745"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_001081906.1"
                     /transl_table=11
                     /translation="MNRRNVVKDLKQFELFAHLTEKKLKGLTEFVYWRTYKKGQFLFLE
                     GDSRERIYFMLDGFVKLERVNQNGNLLYDDYVKRYSIFPYGGMFTDRGYNYTAEAMTDV
                     EVYYIPTVIFEDMVKSSRTQLMYVVQQLSSILKLNENRVQNITIPNAQDRVIQTLNYLM
                     QDLGEQSGEKIVISCPLTTIEISKISGTSRETVSSVLKQLKNDSIVTILDKKITIHNPT
                     YFEEISM"
ORIGIN
        1 ggtaatggct ctcaaggtgg caatcgtgtt aaaggcgata gcaattctca ggagggcaac
       61 ggttctcaag gggataatgt aaaagataat acaaaaaaac aaggtgataa attacctaat
      121 actgcaacgc attaccctat atctatttta atgggtcttt caacattcct aattggtatg
      181 ttactgttta ttcgtcgtaa aaacgtaaaa taagagcaac attcttccat ctaaagaata
      241 catgaaatac tgtataaaac taaaaaggac tttggattac attttattat gcagcccaaa
      301 gtccttttta tcacctatca gaaaaagtat taatacgctt ttccccaata caccatttgt
      361 ttagcttctt taccacaaca aatgcattct tcagctaaat gctcttgctc aaaaggcata
      421 caacgtgaag atacgccaac ttcttctttt agtttttctt cacaagctaa ttctccgcac
      481 cacattgcct taataaagcc ttgcttttcg tcagctattt ttttcatctc ttcgaaattt
      541 gtcgcaacat acgtattctc atcgcgaaat gcttttgctt tattaaataa agcaatatga
      601 atttcttcaa gtaatgctgg aatacgttct tctaattgat ccattggtac aaattctttt
      661 tccttcgtat ctcttcttac aagtacaact tgattctttt caatatcttt agggccaact
      721 tctaatcgaa ttggaatacc cttcatttca tactcattaa atttccaacc aggcgtttta
      781 ttactagcat ctatttttac tcgtgcaacc ttttgaatat gtccttgtaa ctctgttgct
      841 tttgctaaaa ctccttcttt atgctgagca attggtacaa taacaacttg cactggagcg
      901 acttttggtg gcattacaag tccattatta tcgctatgaa ccattattag cccgcctatc
      961 attcttgttg atacacccca agatgtttgg tgcacatatt gccacttacc gttacgatct
     1021 aaaaacttaa tatcaaatgc ttctgagaaa ttcgtcccaa agttatgaga ggttcctgtt
     1081 tgaagcgctt ttccatcatg cattaaactt tcaattgtat aagtttcctt tgctccagca
     1141 aacttctctt tttctgtttt ttgtccttta ataactggta tcgctaaata atcctcacag
     1201 aaagaagcat ataagtttaa aatatttaat gtttcagcct gcgattcttc tgccgtttca
     1261 tggattgtat gaccctcttg ccataaaaat tcagtcgtac gaaggaatgg tctagttgtc
     1321 ttctcccaac gaactactga acaccactga ttatataact ttggcaaatc attataggat
     1381 tgtacaattt ttgaaaagtg ctcacagaat aaagtttcag atgtaggacg tacacaaagt
     1441 ctttccgcta acttttcatc cccgccatgc gtaacccatg ctacttcagg agcaaatcct
     1501 tcaacatgat ccttctcttt ttgcaataaa ctctctggga taaacattgg catatataca
     1561 ttttcatggc cagtttcttt taacttctca tccatcacct tctgcatatt ctcccataag
     1621 gcataaccat acggacgtaa aatcatgcac ccttttacac ttgaataatc aacaagttcg
     1681 gcttttttta caatatcggt ataccactgc gcaaagtcct cttccatctt cgtaatggct
     1741 tgcacttgtt cttttgccat agtcagtctt cctccttcta gaaaatacaa aaaagcccgc
     1801 gtccctaaat agggaccgag ctttgccggc gttaccaccc tgattcatgc acaaaaattg
     1861 cgcatgctct ctttttgata acgggaaatt cccgctgcat atgcagaact caaaggcagg
     1921 ttccatattg cctttttaag aatctttcag cctggcggat tctctctcta ctaaaaaggt
     1981 tgaatatgta ctagtccttt ttcatcgtta taacgaaata aatttgttga ttatcataat
     2041 acaaattctt ttttaaaaca atagctaatt ttcttattat tatatattct tttcattttt
     2101 tgcagtttta tacgtagctt tttcgagaga tttttacaag ttgatgtgca atcataccaa
     2161 taagtgtacc tagtagaacg aagaaaccaa taaatccata tcccattcct tcccacccac
     2221 caataaccat catggtaaca ggaaacgatg ctaagcaaag aagtattaca ataagtgcaa
     2281 atataatatc aaactgtttg tctggaaaac gtttctttag taaatatgaa atagcaaata
     2341 caaggagaat tgtgatacca ccaatgctgt aaaatatacc gaatccatct aaccagtcca
     2401 tactattccc tccttccata gattccctta tacttattat atgtttaatt tttctgaaaa
     2461 taaacaataa attttattcg aaaacatatt tttattacta ggtattaata gtaatatata
     2521 agaataggtt tcatataatt aggaggatta ctttatggat aaagcattaa cgaatcgtgt
     2581 cattatttta tcattcgact gtttatcagc tttagatttt cctatactac aaaaactacc
     2641 tcatttccaa tctctaataa aaaagggcac ggttgttgaa aaagtagaac caatttatcc
     2701 ttctgtaaca tatccaagcc actcaacaat cgtaaccggt aattacccta acaagcacgg
     2761 tgttgttagt aatacgttac ttcaaccagg acgtgaatca cctgattggc attggtaccg
     2821 aaaatcgata aaaggaacaa cattgtatga tgaagcgcgt aaagcaaatt taacgacagc
     2881 tgcccttcta tggcctgtta ctgggagagc aaacattgat tacaatttac cagaaatttt
     2941 ccccaataga ccgtggcaaa atcaagtgtt agtttcctta tttagcggta gcccactata
     3001 ccaattagat ttaaatcgtc gtttcggcca tataagaaat ggtttatcac aaccagaact
     3061 ggatgatttc gtcctcgcct ctgctgtgca tacaatccag acgaaaaagc ctaatgtcat
     3121 gttcgtacat ttcaccgatt tagacacaca aagacactat cacggctttg aatctaacga
     3181 aacaatagct gcaattcata gacatgatga gcggctcggg aaaattattc aaactttaaa
     3241 agacagtgac ctatacgaag agagtacaat tatcgctctt ggtgaccata gcgctttaag
     3301 tgaaaacaaa gcaattcaat taaatgtgct attccaacaa aaaggcctcg tatctataaa
     3361 taaaaaaggg ctattagtag attggaaggc ctattgtcaa agttgcgacg ggtctgccta
     3421 tgtatatgtg aaagacaaaa atgatacgga tacaattcga gaagtacaac tactccttga
     3481 agaactgctg caaaataaac agaatggaat tgaatttata cttcatgatg aagctgcgaa
     3541 agactgcggt gcagatggta attgtttatt tatgttagaa gcgcaagagg ggtattattt
     3601 cactgaaaac tatacaggag attttataaa agaaattact gaaaaagatg ttacgcctag
     3661 taaaaaatat acatttggta cgcatggata ctctccaaca aaacctaact atgaaacaat
     3721 ttttatcgct gctggaaaag gaataaaaac cggcgttacc gtcccgtata tgagacttat
     3781 tgatgaaggt ccaactatcg ctagactact cggtttacac ttaggcgaaa cagacggatc
     3841 aattgtagag gatttactcc aattgtaaag aactgtgtat atatgtaaaa gttctgtaaa
     3901 aatcatcact gtttctcttt ttataatttt tatttttgta cactgttagt agaacaaatt
     3961 taagggggaa cactatatgg aagaaatgtc cagacaagaa aaaagctgga tattatacga
     4021 ttgggcgaac tcggtatatt cgctcgttat tacaactgca ttatttccaa tttactttaa
     4081 agcagctgca aaagaagccg ggctatctgg tgcaacttca acagcatatt ggggatatgc
     4141 aaactcgttc gctacacttt taatttctat acttgctcct attctcggca cagttgctga
     4201 ttataaagga tttaaaaaac gatttttcac attcttcttt ggacttggta tcgtatttac
     4261 aagtatgtta gcagtcgttc caacatctca gtggtactta ttattaggat gctatatgct
     4321 cgccttagtt ggttttgctg gagccaacat tttctatgat gcatttttag tagatgtcac
     4381 ttctgaagat agaatggatc gaatttctac aagaggtttc gctttaggct atattgggag
     4441 tactattcct tttatcggtt gtatcgctct tattattctt gctcaaaaag gaactatccc
     4501 tttatcagtt ggcattgcta gtcaaatttc attcgcgata actgctcttt ggtgggggtt
     4561 atttacaatt ccaatgctta aaaacgtaga gcaaacacac tatattgagc gtcatccaag
     4621 acctattaaa atgagcttca aacgtcttgc tgatactttt aaaaatatta aagaatataa
     4681 aactgtattt atgtttctaa ttgcttactt tttctatatt gacggagtcg atacaattat
     4741 tactatgtct acagcttacg gaaccgacct cggtatcagt gcaacgaatc tattaatcat
     4801 attatttgta acacaaattg tcgcttgtcc atttgcgtta ctatacggaa aactatctga
     4861 aacatttact ggtaaaaaaa tgttatatgt cggtatcatt atttatatca ttatttgcac
     4921 atatgcttat ttcttaaaaa cgacacttga tttttggatt ttagcaatgt tagttgctac
     4981 atctcaaggt ggtattcaag cactaagtcg ttcatacttt gcaaaactag taccaaaaga
     5041 atctgctaat gaattcttcg gattttataa tatctttggt aagttcgccg caattatggg
     5101 cccggtatta gtcggtgtta caacgcaatt aacaggaaaa acaaacgctg gtgttcttag
     5161 tattattgta ttgtttatta tcggtggatt cttactcact agagttccag aaaataatac
     5221 atccgttaca ccacctagtc caaagactaa aacgctataa gaaaagatcc tcttctcata
     5281 agaagaggat cttttttatt tttaacggtg cgccttataa tgaacgactc tactgcttgt
     5341 acaaaaataa tttatcaaca gttgttccta atacttcagc taaacggaat gctaacgcta
     5401 agcttggatc atatttatta ttctcaattg catttatcgt ttgtctagaa accttgcatt
     5461 tatcagctaa tgcgccttgt gaaatattat tttcagtgcg taattcatag atttgatttt
     5521 tcacaccatt gctcctaacc tgtaaaatcg tttttacaac atcagtatat aattggctca
     5581 tatagttgtc aaaagttcct caaagaaaaa gggagcaatt ttgctccctt acaatagtta
     5641 tttcgaagct aacgaatttg ttagtgcctc tttattagca acatcttctt tttttatttg
     5701 catacgtaga actggcccta tcgctaataa aataagtgcc atcgctatac aaaatacagt
     5761 aactagtgaa gttagttcct ttaatcctcc agctagtgaa gttccaatta gcattgcccc
     5821 cataaacagt ggtaaaatcg tcccatttac tcttccaacc atattttctg gtacaagttg
     5881 aatcataagc gtaccgacaa cgatattaac acaagctaaa caaatacctg ttccaaatct
     5941 catgaaacta gtaatccaaa atgatgtaga tagcccttct actaaaaatg acatcgctaa
     6001 tatgctcatg ccgaatacaa acatcttttt cggattcact tttgaagcga aaactgcagc
     6061 aacaatacca ccaattaaca tacctattcc atcagctgca gctaaatatt gaactgcttc
     6121 cttttccatt ccaaggcgtt ctattacaag gaatacttct aatggattcg ttaatccaac
     6181 agctaaaccc ataattgtaa aagtgatcgt aatcatacgt aaatttttcg tgtgaagaac
     6241 gtatttccat ccttctttta tatcattttt taatgaatct cttgccactt gctctttttc
     6301 aacccatttt ggtaaaaatg aaaggatgat agccgataac aaaaatagaa tgattaaact
     6361 atatagtgac gtaaataaac caagttgtgt atacacaagc gatcctacca ctggcccaaa
     6421 aattagaaat aatgactgta atgtttggtt aaatgcaatc gcatttgcta cctgttcttc
     6481 ttttacatag cgcttaaata tacgcgaaga tgagggctga gaaaactgac ctacaatcgc
     6541 ggaaatgagt gttgcaaaaa atatagcctg ccaataatct agctttaaca acaggacaat
     6601 tcctataata gacagtacac tcaacacatc tccagcgacc attgttcttt tcggattcca
     6661 gcgatctgct aatgcaccac caatgaacga gaaaataaag ataggtgcat actccatgac
     6721 agataataga gacactgaaa ctggatcatt atttgtccgc tccattatga aatataaaag
     6781 agccatattt ctaatccaaa ttgcaaattg ttgtaaaata tcagatgcca taacgagcat
     6841 aaatgctcgg tttttaaata aagctttcac tttcattccc cttccataaa ccgaccgttc
     6901 ggtctaattt gttttgtaag aaaagcaact gacttattat tcagctgcca ttccttttaa
     6961 caatacatct attgcctttt tataaatacg tttcagctct ttataatcta actcgtagta
     7021 aagtactcca agccctgata ataatccgtt cacaatatac ataagatcac gagcattatc
     7081 ttcacggaac tctccagact gtatacctgc ttcaattaat ttctcaaaca taacatatga
     7141 ttctctagtt aaagctaaca gttcatccag aatctcttta cttacaattt ggctcataga
     7201 gaattcctct attgcatttg aaattggttg ctgtatgtcc tctacatgat attccgcgag
     7261 accatatagt ttttcagtac tagtactata caacttctct ttttcattcc atttttcaac
     7321 ccaatcatac gtatgctgtt tcactacaaa taaaaataat tcttctttac ttttaaagtg
     7381 ataataaatg cttcctttac ttcgctctgt aatttcacaa atctcttcca tagatgtagc
     7441 tgcatagccc ttctgtgaaa atagactttc tgctttatat gcaatttctt tctttatctc
     7501 ttctgcgctt cttctcatat tcacacctct ttaaaccgac cgttcagtct aataataaca
     7561 aatcaaaaac ctctatcgca agaggatata ttccttattt aagaaaacgt actttcaaac
     7621 caagttcgaa tcatatgtat cgttccaaat ttaaatgcta atttaacaag aaatacgcct
     7681 cccgcagcta ataaaaataa cactactttc cccttatttt tcactttcgg ttcccttttc
     7741 atttccattc cccttagtat attaaaaata ttaatcaaac gtttgtttaa ctgtgtttat
     7801 gcatatgtaa gccaactaat caaacatttg tttaaaaaga aatacgccta tataaggcgc
     7861 attttcatca atcaccgcca ccaccgcagc ttccaccgct atctccccca aaagaccctc
     7921 cacaatcatg tgagccgcca tcatgcgagc tatcattatc agatccagca aagaaaaata
     7981 atggtgatga gctgttagat gaattatgaa tgttattttg ttttgtaaga tttaccttct
     8041 ttttgttcga tcgaactgct gttacgatta ttccaactac aacaaataat agtatgacga
     8101 taataaattc catataaaag cctcccttat tcctcgaata attgaatggt tctctctaga
     8161 ttttcaagtg aaatgaagcg cgattctcga aggatctctt ttccattata aaataataaa
     8221 attgtcggtc ctgtaaatac ggcatatcgc cccgcaatct cttgcatgtc ttgtagtaat
     8281 atctctattt tctctacgta atcataattc tctaatacgc aatttacttt tcttagcata
     8341 acatcacaaa caccacaatt ttccgtttta ataaacagaa gtaccaattg ttgttcttcg
     8401 atataggtcg ctaattcttc tatcgtttta aatgtagtca tcttatccct cttagcgtaa
     8461 tttacgaaat actttgtctt gatacatacg aaaagctgaa ctatctttaa tctttctctt
     8521 ttccattacc tgctgaaaac gaagcgtttt tactgttaaa tcttctctta atttctttct
     8581 ctcttcttca tcataacagc aagcaattag atcctctatt tttaatatat ctttttgtag
     8641 ttccatttct gttggaatca ttcccgcatt ttttaaaatt ttataactca ttctaagttc
     8701 tggaggtacc attgaaatat cttctaattg tagtggtttt ccttttcccg gaagataatc
     8761 aagatcccca ttccgtatcg cttgtcgaat tttttcttca gcaatgttca aaaacacatc
     8821 cacactgttc cctcctttac atatttttta ccattatttt acatgatatt tccttatctt
     8881 tctacgtctt taataattgg ctccatacaa ttttttctca aatttattta taatgagcta
     8941 tttcctccca taccaatctt tcgttttcat atatagtttg tattcaagcc tttttgtatt
     9001 gagaaagtct tttacaaacg aataaagcgt ttacactaaa tcttacattt gttacgattt
     9061 aatcaccccc agctcccttg tatagacttc gtgatgtctg atcattttat ctagacgttt
     9121 catacgtcta gattcatttt gatttattgg cgtatgcctt taaatatatc ttttatttcg
     9181 aaaggagaaa tggctatgag gtctcaaaaa ttcacactgc tattactatc tctactactt
     9241 ttcttacctc tttttctcac aaattttatt actccaaatc tcgcattagc agattcacca
     9301 aagcaaagtc aaaaaattgt tgggtacttt ccttcgtggg gcgtttacgg acgtaattat
     9361 caagttgctg acattgatgc atcaaaactt actcacctta actatgcttt cgcggatatt
     9421 tgttggaatg gaaaacatgg aaatccttct acccatcctg ataatccaaa taaacaaacg
     9481 tggaactgta aagaatctgg tgtaccattg caaaataaag aggttcctaa tggtactctc
     9541 gtactcggtg aaccatgggc tgatgttacc aaatcgtatc ctggctcagg tacaacttgg
     9601 gaagattgcg ataaatatgc ccgttgcgga aatttcggag aactaaaacg attaaaagct
     9661 aaatatcctc acttaaaaac aattatttcc gttggtggct ggacttggtc taaccgcttt
     9721 tctgatatgg ccgctgatga aaaaacaaga aaagtatttg ctgaatctac agtagctttt
     9781 cttcgcgcat atgggtttga tggcgtagat ttagactggg aatatccggg cgttgaaacg
     9841 attcctggtg gtagttatcg tcctgaagat aaacaaaatt tcactctcct tcttcaagac
     9901 gtccgaaatg ctttgaataa agcaggtgct gaagatggca aacaatattt actaacaatc
     9961 gcgtcaggtg caagccaacg ctacgctgat catacagagc taaagaaaat ttctcaaata
    10021 ctcgattgga ttaatattat gacatatgat ttccacggtg gatgggaagc tacttctaat
    10081 cataatgcag ctctatacaa ggatccaaat gacccagcag caaatacgaa tttttacgta
    10141 gatggtgcta taaatgttta tacaaatgaa ggtgttccag tcgataaact agtattaggc
    10201 gtaccttttt acggacgtgg atggaaaagt tgtggaaaag aaaataacgg acaatatcaa
    10261 ccttgcaaac cgggtagcga tgggaaactt gcttctaaag gtacttggga tgattattct
    10321 accggtgaca caggtgtgta tgattacggt gatttagcag ccaattacgt taataaaaat
    10381 ggttttgtac gctactggaa cgacacagct aaagtacctt acttatataa tgcgactaca
    10441 ggcacattta ttagctacga tgacaatgaa tctatgaaat ataaaacaga ctatataaag
    10501 acgaagggtt taagtggagc aatgttttgg gaactaagcg gggattgccg tacaagtcca
    10561 aaatatagtt gtagtggtcc aaaattactt gatacgctag taaaagaatt acttggtgga
    10621 cctattagtc aaaaagatac tgagccacca acgaatgtta aaaatattgt agttacgaat
    10681 aaaaattcaa gctcagttca attaagctgg actgcatcca ctgataacgt aggcgttact
    10741 gaatacgaaa ttactgccgg agaagaaaaa tggagtgcaa caacaaatag cattacaatt
    10801 aaaaacttaa aacctaatac ggaatacaca ttttcagtaa ttgccaaaga tgctgctgga
    10861 aataaatcac aacctaccgc tcttactgtc aaaacggatg aagctaatac gacacctcct
    10921 gatggaaatg gcactgctac attttcagtc acttcgaatt ggggcagcgg ttataacttc
    10981 tcgattataa tcaaaaataa tggaacgact cctattaaaa attggaaatt agaatttgat
    11041 tatagcggca atttaacaca agtttgggat tctaaaatta gtagtaaaac aaataatcat
    11101 tatgtaatta cgaacgcagg atggaatggc gaaattcctc ctggtggatc tattacaatt
    11161 ggtggtgcag gaacgggtaa tcctgccgaa cttttaaatg ccgtcattag cgaaaactag
    11221 acgtaatatc cattaattat ttcactaaag tttgaattta ggttcgagaa atacctccta
    11281 aattcaaact tttaatttta tgaaaaatca aaaatatcaa aataacctat tataattata
    11341 tttagtttct aatatgaagt ttatatgaag ttcatttgaa ttttacatga attcccttta
    11401 atttctattg tcttcctata atatccacat tatcctttac atataggaat tatttttatt
    11461 ccattttgaa ctatctatat atataaagaa agatagtcac ctgttaggga aaggctttcg
    11521 tattattata aatataacaa aagaaaaagc acgcttataa gcgcaccata agagtgcttc
    11581 ttcatacaat tctcatgtaa gagttctcga aaatcatgtt aatcacaaag aaaaggcatt
    11641 agctcataaa agctaatgcc ttttctttat tcatattgtt cagcattcca atcttctata
    11701 ttccatactt ttgttatcca cgattcatag aaagaaggtt catgtgagac aattaaaact
    11761 gttcctttgt attgttgtaa cgcttcctgt aaagccatct tagtttctac atccaaatga
    11821 ttagtcggtt cgtctaaaat taaaacattg cttttcgtta cgataagttc acataaacgc
    11881 actttcgttt gctctccacc gcttaataaa cgaataggtt ttaatacgtg ttcttctttc
    11941 aatccacact tcgctaatgc ttggcgcact tctttctttg tcatatctgg ttgttctgcc
    12001 caaactttct ctaacggtgt tatttctgaa gcaaactctt cctgtgcaaa ataagcagga
    12061 tttactcgtt ccccaacaaa aattgaaccg cttagcggct ttatttgacc taataacgtc
    12121 tttaacattg tcgtttttcc aataccgtta tgaccaacaa cagctatctt ttctcctttt
    12181 ttcacttgta aattcaagtc tggaaataac ggctcactat aacccactct tagtttctca
    12241 gcctgtaata tacgacttac tggttcatta taaacagtaa aagcaaaacg ggaccgaggt
    12301 atattattaa ccttttcaac cctttgcatt ttctccaata ctttctctcg actttttgcc
    12361 tgttttgctt ttcgaatctt atttttttga ataaatgttt ctaactgagc aatttctttt
    12421 tgttgtttca catacgccga ttgtaattgt ttcctttgta cttggtaact ttgtaaaaac
    12481 ttttcataat cccctacata tcgcttaact tttcgttctt ctagatgata aatgacattc
    12541 gtaatattgt tcaaaaatac ttcatcatgc gaaatgataa tataagcttt ttcgtacagt
    12601 ttcaagtacg attgcaacca ttctatatgt gctgtatcta aatagttcgt tggttcatct
    12661 agcaataaaa catcagcttt ttctagaaga agctttccta gtaataactt tgtccgctgt
    12721 cctccactta actttgaaac atccttttcc aatcctattt caaacagccc taaaccaatt
    12781 gccacttctt caatttctgt atgaatttga tagaaattag agttttccaa tatagtttgt
    12841 aactctccat accttactaa caatttttct acttctactg cttcagccat ctcttctgca
    12901 atttttaaca tttcgtattc aatcgcatac aagttagaaa atgcactttg caagtatcct
    12961 tcaattgtta ttccttcttg taaatctata tgctgctgca aaaatccaac cttcacatgt
    13021 ggaaaccatt caatgttccc atcatcatgt ataagttctc ctgttaaaat tcttagcagt
    13081 gttgattttc caatcccatt tttccctact aacccaacat gctccccctt taataatcga
    13141 aagcacgcat tatataagat ggttttctca ccatacgaat gacttaaatt ttctactgtt
    13201 aatatactca tttttttctc tcctttactt atcgtccata agctaaatag agagaccaac
    13261 agtatgaagc cttatttaat tatgcatata aaaaatgggt aaggtgaata caccttaccc
    13321 attacatatt atcgtaaaaa aggattaagg ttctttacct gctgtcttca atttagctta
    13381 atcttaaaaa atgggcagac ttcttccata tcaagctaaa accatttgaa gaacagttga
    13441 taaagtcatt ttatcctttc actcctttaa catttgttat attaagagta taaactactc
    13501 tgttatattc tattctctat tttccctttt gttccttctc catcttttca tattctaaaa
    13561 aaagcctctt aacagtaatt atactaaaaa ctgttaaaag gctttttcta ttttttcata
    13621 taaggagcta acacacttaa aatctcttct ttatcctttt ttaattcgag tgatgttaac
    13681 atatccatcg ttctcggtct aggtaatttc acttgtacct cgccaacaat tgacgctggt
    13741 ctttgagata aaataaatac gcgatctgaa agcaagattg cctcatctaa gtcatgtgta
    13801 accataacga ttgtttgctt ctcttgatgc caagagttta aaagccagct atgtacttcc
    13861 atttttgtaa atgcatctaa ctttccaaaa ggctcatcaa gcagcataat tggcttttca
    13921 cataaatatg tgcgcagaaa actaattctt tgacgcatac caccagacaa ttcatctgga
    13981 taatggtctg catattcatc tagttcgaac tgctttaatg cttccattcc ttctgtcagc
    14041 ctttgttttt tcggctttcc ttcaatttct aacggaagaa cgatattttg caaagctgat
    14101 cgccacggta gtaataaatc ttgttgtggc atataactaa caacatcttg ctcttgtact
    14161 tgcttatctt tatacattac gttcccgctt gttggttttt caacatttgc aatcatgttt
    14221 aataatgtgc ttttcccgca accactcggt cctacaaagg aaacaaactc tccctcttgt
    14281 atacaggcac taatattctc taatacattc tttccgtcga aagatttcac tatatttttt
    14341 atttgtaatc cgctcatttt tcacttggaa ggaattcatt tgtaaaagca tcttttacat
    14401 cgattttctt tttaataact ttgttgtcat ataagaaatt catgtaattc gtccaaattt
    14461 cttccttctg tactccccat gctttcgcat catcttgata cttcgtactt aaccatttct
    14521 ggctttcttg aactaaatct ttatttacat ctggaacagc tttaattaga atatcagcag
    14581 cttctttcgg ttccttaatt gcaaaattat aaccttctgt tgttgcactc ataaactttt
    14641 tcacaaagtc tttatcttgc ttcgtatgtt tttcactcgt aataataaca ggactataga
    14701 aatcaagcgc tggatctaag tccttcacca taatcgtatt taactctttt ccttggcgct
    14761 tcgcttcaat accatcccaa ccgtaataaa tccattcgaa atctgcatca cgaccgattg
    14821 atttaaagaa atctgtttgt cctaagatga ttttttcaac tttattaaaa tcagcttgat
    14881 gcttatccat aatcgtcttt aatgtcgctt cttccgctgg tcctccccag ccgccataac
    14941 gtttaccttc aaaatctttc ggtgacgtca tattatcttt cttaagcgat gcaaacgctg
    15001 aagtgttatg ctgaataatc gctcctacag atacaacagg aattccttcc acacgagcta
    15061 atgttacatt ttcttgtgcg cttattgcga agtctgcttt tcctgatgct atcatttgct
    15121 ctgctgttac attgtcacct ggttgaataa tttctacatc taatccttgt tttttgtaat
    15181 aatctttcgt ttgcgctaca tacaagccag tatgattcgt atttggaaac caatctaata
    15241 ctacttttac tttttgatct ttacttgtac tttcttcttt cttcgccgga ttacatccag
    15301 ccacacctac cgctactaag gcagctaaca taactttcaa accttttttc attttctgcc
    15361 gtcctttcta tatatccatg gtgctgttat tcttgccata aactctacga taaaatacag
    15421 gcataatgtc actataacga tgattgctgc aacaccaaat actcgggcag tcaaaaagga
    15481 ttttgtagcc ctcgtaagca taacgcctaa tccttcactt gcaccgagcc attctccgat
    15541 aattgccccc attacgctat atgtaactgc aatttttaaa ccggagaaaa agtatggaag
    15601 cactgctgga aattttactt tctggtaaac ttgccatttt gtcgccttca ttgtttgtaa
    15661 cagcttcaac atgtttttat ctactgtttg aaaaccttct aaaatactaa gcgcaattgg
    15721 gaagaaacaa acgagtatta cgaccattac tttcggcaac atcccatatc caaaccaaat
    15781 aataaatagc ggtgcaagta caacaattgg aattgtttgc gaaataacga gcaatggatt
    15841 tattaaaata cgaaataacg gtataacgtc cataataatt gcgatgctcg tccccaataa
    15901 aattgcaaag aatagtccaa ttataacttc ctgcagtgtt tgcatcgtat ttggtaatag
    15961 taaatctttc atcccaatta attcttgaac aatggcagaa ggctttggta aaatccacgg
    16021 ttcgatttta aataatgaaa cagatccttc ccatatcgca atgagaagga taagccaaat
    16081 agttgtaata agtttagatt gcttctggtt ttgcatattc atcacggtac ttccaaacct
    16141 tttcatctat cgttacacca gtgcttggac gataatggat tttaatagaa gtaatcactt
    16201 cttctgctcc agcatcgacg caagcttgtt gcgcacgttt aacgacatca agaagtacat
    16261 ctaattctcc ttccaaagtt gtttccattg cccctacttc ataacgaact cccgattgtt
    16321 gcacaacttc aattgcttta tcgacaacag aatatacatc tttcgttttc gcttgtggta
    16381 ctactgaaaa tgacattgta acttgttgtg acataataaa atccccctta taaaattaga
    16441 tttcaaaaat aagaaaaggc tttcctactg cgtaggaaag ccttgtatgc aagttattat
    16501 agaataacat atgctacatt actttaagta actccctacg ctggcattat ccagatcagg
    16561 ttgagggtcg atgtttactt acatcctctc agccaattgg ctccccggtc cttaattcgt
    16621 tttcattgta gcatgattta ttttattgaa caaacaaaag catgcataat catttcatta
    16681 tttttggaaa ataaccaact ttttcaccat gagctaataa ctgctgaata aattctttat
    16741 taattgttgg tactatcaat tcttttttct taatccattc attcgttcta cgcgtaccca
    16801 ttacaatttc agattgctgc gctccatctc ttgcaacttg agaagcaatt aactctgcta
    16861 ttacttcatt tctcttcgct aattcaagtc cggtatttac atattctgaa agtggaacca
    16921 tttcaagatt gtatccacac tctccaatta gctgtataaa ttgttcaaac tcaatttgat
    16981 gtggatgaca aatatgtaac gtctctccta caatttgcgc atcttgtaaa tacgatacaa
    17041 ttgatttact agcaaaatca attggtgtga aatcaacttt ccacttcaca tttggtgcct
    17101 tcccaattaa tagcattgtt ttaataagac gataaaatgc gtttccttca atattttgtt
    17161 ggaacgaacc tgtttctgaa tgacatgcta aattacctgc acgataaata tttccgcgca
    17221 aaccattttt cattgcttca cgaacaatgt tttctgcttg tagtttacta tttgaatata
    17281 cattctctaa gtctacactg taattaaaat caccagtttt catgtatgta tcccattgat
    17341 ctaccgctaa ttctaacggg ataccaattg tagaaataaa atggaatgta gcacctttct
    17401 ccgctaatgc tagcatccgg ctagttcctt ggacatttat attttcaaat tgttttacat
    17461 ctccaaaatg tcttacatct gcaccgcaat gaattatcgt atccatctta gaactgatga
    17521 acataaattc ttcttcgctc atcccaagat actcttcccc cagatcacca gctacggcct
    17581 gtatacgctg taaccattct tcacatatat cactaaagta gcctgttaat gtatttataa
    17641 ttctttgctg cacatctttg gttggtctta ctaaacaata aatagtagca gatgtatctc
    17701 tcaacaattc atataatatg tgtgatccta aataaccagt agctcctgtt aaaaagacat
    17761 ttgaaatctg ggtttcttcc aaaacgtttg catacgtgat agtatctggt tcgtgaatca
    17821 ctttatattc acgaaatact tcttctttct ctacttttac ttctcgctca attcgagcta
    17881 atccatatat cgttctttct ttaaagaaat cttgaattgt taaatgtgag aaatcttctt
    17941 ttaacaatgt taagactcgt aatactttta atgaatgtcc accaattgta aagaaatcat
    18001 catgcactcc aacttttgaa attcctaata cttccgccca agcgttcgct atttgttttt
    18061 ctgctttatt agaaggtgca acatattctt gtagacgaac cgcttcatac ttttcttcta
    18121 actgagctaa cttcttaaca tcaatctttt tattaggtgt aagtggtaat tcattaatat
    18181 aaattagttt agatggcacc atataatctg gtaattgctc ttgtaactga taaactaatt
    18241 ctggtatttc ttttttattt aaagttgtat agaacgcgat taaatattgg ctaccttcct
    18301 tactcttctt agcaaaaaca gcattttctt ttatattatg attttgagaa attttacttt
    18361 ggatttctcc tagttcaata cgatgtcctc taatctttac ttgatcatct ttccgatgta
    18421 aaaactctat atttccatcc tctagcaact taactatatc acctgttttg tatatattaa
    18481 ctataggatt gaaagggttc ggaataaaag cttcaattgt tttattaggc ttattaaaat
    18541 acccttttgc taatcctact gaatctatat ataactcacc aggtacacca attggacaaa
    18601 gattcatatt ctcatccaaa atcataactt gataattagc acatggttta ccaatgggaa
    18661 tactcgcaac atcctcattt aactgactag gtattttata ggttgtcgtc actacagtac
    18721 attctgtcgg tccgtataca ttatgaattt caacattcgt acctattctt tctctccaca
    18781 atttaataac ctctacaggc aacatttcac cgccaatcgc aattcttttt agggaagcta
    18841 gcttatatat atctccttct gctaaataag ttgctacttg tcgaacaaaa attgttgcta
    18901 atgccaagat cgaagttgct ttcactttat agattgcatt tgcaaatgct tctacagaca
    18961 atcgctcttc ctctaataat acatacaagt ttcctccgca gaataaagaa gcaaatgact
    19021 cccatacaga agcatcgaaa ctaaaggaag gaaattgggc aaatacatcc tcttctgtca
    19081 attcatattg cttttgcatc caagtgtaca gattaacaac gcctctatgt gctaacatcg
    19141 ttccctttgg attccctgtt gaaccagatg tataaatcat ataagctaca tcatcacaat
    19201 gaatagacaa ctttacatct atatcttcac aagtttcact atcatacatt gaaactgttt
    19261 gaaccccatc acatgttata ggcgtctctt tcatcaatat aactttcgct tggctatctt
    19321 gaataatgta ctgtattcta ctttccggat aatctggatc aatcggaaca tacgctgccc
    19381 cagcttttaa tatagctacc atacttacta ctgtgtctat gctacgtttc ataaatattc
    19441 caacatagtc tcctaattgg acgccatttt taattaacat atgagctatt tgattacttt
    19501 ttttatttag ctcctcataa gttaaagtac cttcccttga agataaagct atacgatttg
    19561 gaaattgagt aacagtatta tagaacatat cgacgatact tttctcagga tatactgctg
    19621 tcgtatcatt cacttgacta taaagtgcca tctcggcctc tgtaataata ttaaaatttt
    19681 ttatataatt attcttattt tgtgatgtac caattaaaac accttgtatt tgttgtgcat
    19741 aacgagtaat cgttgtttct ttccaattaa cactattaaa tattatttct acactttgca
    19801 tatttttact aaatacaaat tgtaatgtat tcgtgtcttg tagctgataa tatgtttcac
    19861 caataataat aggtgacatt tcatataatg tattaccgtt ttgaaactct tctatttctt
    19921 cctcattcat ttctttaatt tgttccagtt gctcttcaat ctgtaaattc aaactttcat
    19981 aggagagaaa attagaaact tcaatagtaa tcggaaataa acttcctctt acatgataaa
    20041 gcacgacaat atgtttttct ttagaaatat gatataacca cgtggcagtc gctcctatta
    20101 aatctacaat gtgagtcaaa tttagaaata gttcagtttt cctttttatc ctaagttccg
    20161 ttccttgcac atctttaggt attttaatac ttccttctac tttccctaaa aattctttta
    20221 ccatctcatt ataagaaatt gctaatttca tatttatgta aattcctctc ttaaatataa
    20281 taaaggtgtg aaaattcaca cctttttcat cccttattaa cgggcagatt cgttcaattc
    20341 ataatcagta gcggagatat cccctttgat tagaattgaa ctttctcctt attcgctttt
    20401 aaactcacca ataagctctt gtaattcctg agaaagccaa cttaaagaag tcgctaattc
    20461 tgcaatatct tgtactgata tttcttgctc tttcatgctt tcttcaacat tactactgct
    20521 gttggcataa gtatttgcaa tatgtgataa ttcatttacg acttgaacga tattctggct
    20581 attttgtaaa atgtcactcg aattacccga aacagctttt acttgatctg taacagattg
    20641 cgctgatttg gagatttttt cgaagaaatc tccactactt tgaacaagtg aaattccagt
    20701 ttctacttct tttgaacctt tttgcattga aactacagca tcttctgtct cagcttgtgt
    20761 ttcaccaatt aatttcgcta tatcttttgc agacgcttca gtttgttctg ctaattttcg
    20821 tacttcatca gcaacaactg caaaccctct tccagctgct ccagcacgtg aagcctcaat
    20881 agaagcattt aaagctaata aatttgtttg atttgaaata cctgtaatta cagttacgat
    20941 atcactaatt tcttttgacc ttgtttctaa cgaataaatg atggaagata aatcttgtac
    21001 tgcattttgg attaaactca tttgattaat aatttgtcca atcacttcat taccttcaat
    21061 tgaatgttgt tccatacctt cagaagcaac cgcaacttgt tttgcagccc cagttatttc
    21121 ttctacctta tcttccattc catgtacaat tcctaaacat tgttgtactg aagttttttg
    21181 agactgtgcc cctactctta aaccttcaat agaacttgca atctcttgaa ctgccatgct
    21241 gttttcctct gtactcgccg acaattcttg tgaagaagaa gaaacttgct cagcagtttg
    21301 ccttacttta tctataatcc ctttaaattt ttcaatcgtg ttattgaaat aaacattaat
    21361 aattccaata tcatctggtc tttcttttaa tttaatactc aagtcacctt caccaatttt
    21421 acgtaaccct tctcgtaaat cttttaatgg cgctaacgag tgacgcacga taaagaattg
    21481 agtaatagtc gcaatcgcta atgaaataat gataaagagt aagccctgta tcataaactt
    21541 ctcttttgta ataggaacaa tggaagcatc taagtcagcc gcaataattg caacaatatt
    21601 gttttctcca tctgtaattg gttctaatat tgtcacccac gaacctattt catcttcata
    21661 tacttctgtc atttgggcct ttttcgtatc aatcacttta tcgtatgcct tcatccaatg
    21721 agcgggttgt tcataataat ctcccggctt tatagggaac gcatttgtta actctgtagt
    21781 caaaccaacg agttgtaatt ctcgcttttc attcggcttt gctcctgtaa catacgtttg
    21841 tccaacactt ttcaattctt ttgacacttc atctaatttc tctgttaact tttctttttt
    21901 cactttttcg gctgtaggat ctttcgccat gtctctaact aattctacat ccaatttttt
    21961 caatactatt tctcctgttt caatagactg cctttcaaat aaagacatca tactattttg
    22021 aaacatgttg aaacttaacg cacccatact tccaacaagt gtcaaaataa ctaatacggt
    22081 taataagacg ttcttttgaa ggaacgataa cttatgccaa tattttttca ttaatatcca
    22141 ccttccttaa ttaacataac aaaaaaacaa aatatacgaa tattttgttt gaaaatgatt
    22201 ctcaatatat tcgagaataa aaaaaagcca atgtaaaagc attggccaag accaacccta
    22261 tccgtccggt aactggctag catagccttt cgaccttagc tcctgtagtt ttgcgtcctc
    22321 atgtttccat cagtttgcct ttctcgctga acgagttgaa cgatatggga gttctatgag
    22381 aattaattta ttctctttca aagattacaa catataaatc aaaatgtcta cttatttaga
    22441 gatataaata caaattttta acgcattgct ttttcgaaat aatttcaaaa agtacgtgaa
    22501 tgttactttt tttgtgttat ataataaaaa atgtataaat aacaaggatt tcttcgggta
    22561 tttatttaat tttcattcaa attaaactat tcgaatatat cttaactaat gaatttcgga
    22621 ggtagtttat catgttttgg ctacaatttc ttaccttgtt actctgtatt tttattggtg
    22681 cacgcctagg cggagttggt ttaggagtaa tgggtggagt tggtatggca atactcgttt
    22741 ttgtcttcca cttacaaccg accgcgcctc ctatcgatgt aatgcttatg attttggcag
    22801 taattactgc tgctggtgct ttgcaagctg ctggaggaat ggactatctt gttcatctag
    22861 ctgaaaaggc attacgaaaa aatccaaagc gtattacttt ttttgctcca attgttactt
    22921 atttattcac actatgtgca ggtactggtc acgttgccta ttctgtactt cctgttattg
    22981 cagaagtctc tcgtgaatca gggattagac cggaacgccc aatgtcgatt gccgtaatcg
    23041 cttctcaaca agcaattaca gctagcccaa tttcagctgc cacagttgct cttttagcaa
    23101 tgttagctga ctataaaatc actttattag atattttaaa agtgagtatt ccttctactt
    23161 tcattgcttg tatgttagca gcattcgttg ctagtaagat gggaaaagaa ttaaatgaag
    23221 accctgaata cttaaaacga ttaaaagaag gaatgattcc taagcttgaa gagaaaaaag
    23281 aatttgtagg tgtaaagggc gccaaattat cagttatcct tttcctagta ggaactttcc
    23341 ttgttgtact tcttggttca tttgaagcac ttcgtccagg atggatagtt gatgggaagt
    23401 tagctcgtct ttccatgccc aacacaattg agatggttat gttaactatc gcggctctta
    23461 ttattatttt ctgtaaacca aatgtagaaa gcattgtgtc tggtaacgtc tttaaagcag
    23521 gagcaacagc agttgttgct attttcggta tcgcttggat gggagatact ttctttaatg
    23581 gaaacttaaa tatgattcaa ggatccattc agcatttagt aacaagtgca ccttggctat
    23641 ttgccatcgc actattcatt ctatctattt tactgtacag ccaagcagca acagtacgtg
    23701 ccttaatgcc acttggacta tcccttggta ttccaccagc actactgatt gcgatgttcc
    23761 ctgcagtaaa cggatatttc ttcattccaa actacgggac aatcgttgct gccattaact
    23821 ttgaccgtac tggtacaaca ggtatcggta aatacgtatt aaatcatagc tttatgattc
    23881 caggcttaat tgcaacattt acttctatcg gaattggaat gctcttaatt tcaattatgt
    23941 tttaaagaaa aagcacaaac ctttatttaa aaaggtttgt gcttttttaa tcaaacgttt
    24001 gtttaaattt ttggggcagt ctacttctcg atgtagcact taaaatacta catgtccttt
    24061 tctacaaact tctctttact tcttcagcta attttctcgt actttcatac gcagattcag
    24121 ctaaactaat tgctgaaata actgaaacac cgtccgcacc cgcttctata actgccgctg
    24181 tattttcaac tgtaatccca ccaataccaa cgattggcac tgtaattcct tgttctctaa
    24241 aataagctaa tcctttcgtt ccttgaaccg ctttcgtatc ttttttcgta ctcgttggga
    24301 aaataggtcc aacgcctaaa taatctgctc catgttcgat tccaaagcgt gcttcttcaa
    24361 ttgtatgagc agatacaccg ataattttat ctcccatttt ttcacgaaca gatgtaattc
    24421 cttcatcatc ttgtcctaca tgaacaccat ctgcatctaa ttcaatggct aattctacat
    24481 catcatttac aatgaaagga acactatatt ccttacaaag cgtctgcaat tcttttgcaa
    24541 agcgcactct atcttctcca attaaagaac cttccccctt ctcgcgaaac tgaaaaagtg
    24601 tcactccacc atctaacgct tctttcaata cagctaaagg atccctcgtg cagttattac
    24661 ttcccataat aaaatacact tgtaataact tagacatctt ctttgtttca atgcgcatca
    24721 tgtgtttcat cccccttact ctaactcctc aatctttcca tacttctcaa tatcaccagc
    24781 agtagtattc gctaactgat ttaaaaattc aatttggaaa ttaccaggtc ccttttccac
    24841 ggtcttagca gctgccagtt ccgaagctac accataaaac gttaatgctg ctactgctgc
    24901 ttttacataa tctttttcca ctgctacaaa tgctcctatt acagacgtta gtaaacaacc
    24961 tgtccccgta actttcgtta aaatagggtg accgtttcga ataacaatag ttctctctcc
    25021 atctgtaaca acatcttctt ttccagtaat aaccgcaact gtatttaatt cgtctgctgc
    25081 ctgccttgca atacttacaa cattgccatt tccagtacca gcgtctaccc ctttaatttc
    25141 ccatttctca ttaataacat ttgctatttc agctgcattt ccgcggataa ttgctaaatc
    25201 gatttcagcc ggaatatgtc tcgcaacttc tgttcgatac gaagttgctc ctgcaccaac
    25261 tggatcaaat agtactggca cattgttcgc atttgctgat ttacccgcga gtaacatcgc
    25321 ttctacttct tcaggacgaa gtgtccccat atttaatact aacgctccag caatgctagc
    25381 catttctgct acttcttctt ttgcatacgc cattacaggc gatgccccaa gtgccaacaa
    25441 accgttagca gtaaaatttg ttacaacaac atttgtaata ttatgaacga gcggattaga
    25501 ttctctcacc aaatccacta ctttactaat ttctttcata ttcatccttt tcatctccta
    25561 actataatga tgggagatac acaaaaagac actttgcgcg tacgcaaagt gcctgaacat
    25621 gtgcttttac actctcccta cgctggcatt atccaacagg ttcaaatggt caatgacgga
    25681 ctagtagcca tactctcagt ttgtatccac aaactcccat gtgtttctta ttcatctact
    25741 tcaaagtcta ctcttattct agtaaaataa caagttcttt acttttctat ttaatataga
    25801 agcaactgct aaagtgaaac tttaatcagt tgggggtttt ttcatccccc actgattatt
    25861 agttgaacca atcgggcttt tacgggcagt tgttccccca cctaacttat ttgctttcgt
    25921 tgaattttga ggtggggatc ttactgcctg ttaatgcggg ataaagtgaa actttaatca
    25981 gttgggattt tgttcactcc attaaaaaca gctcaaatat ggagcgaaac tgaatctcaa
    26041 gaagatgtat gctatattta acttatggaa atttgaaagg atgtttttaa tatgtcaaaa
    26101 agcgttgtaa tcgctgaaaa accttccgtt gcacgagata ttgctcgtgt actgaagtgt
    26161 gataaaaaag gaaacggcta tcttgaaggt agtaaatata ttgtaacttg ggctttaggc
    26221 catcttgtta cattagctga tccagaaagt tatgatgtga aatataaaaa gtggaattta
    26281 gaagatttac cgatgctacc tgagcgtttg aaattaacgg ttattaaaca aactggtaaa
    26341 caatttaatg ctgtaaaaag tcagctactt agaaaagatg taaatgaaat tattgtagca
    26401 acagacgctg gacgtgaagg ggaattagtc gcacgctgga ttatcgataa agttaagcta
    26461 aataaaccaa tcaaacgttt atggatttct tctgtaaccg ataaagcaat taaagatggt
    26521 tttgcaaatt taaaaccagg taaggcatat gacaatttat atgcttcagc agttgcgcgt
    26581 tcagaagctg actggtatat cggtcttaat gcaactcgcg ctttaacaac tcgctttaat
    26641 gctcagttaa attgtggccg tgtacaaacc cctactgttg ctatgatcgc tagtcgtgag
    26701 gatgaaataa agaacttcaa agctcaaact tactacggca tcgaagctca aacgatggag
    26761 aaactcaaac ttacttggca agatgcaaat ggcaatagcc gtagttttaa taaagaaaaa
    26821 attgatggta ttgtaaaaag tttagataaa caacatgcta ctgttgtgga aattgataag
    26881 aaacagaaga agtcattctc tcctggtctt tacgatttaa ctgaattgca acgtgatgca
    26941 aataaaaagt tcggttactc cgctaaagaa acattaaata ttatgcagaa attgtatgaa
    27001 cagcataaag tgctaacgta ccctcgtaca gattcacgct acatttcatc tgatatcgtt
    27061 ggaacacttc cagaacgtct aaaagcatgt ggtgttggag aataccgtcc cttcgcacat
    27121 aaagtattac aaaagcctat caaacctaac aaatcatttg ttgatgatag taaagtaagc
    27181 gatcatcatg cgattattcc aacagaagga tacgttaact tctcagcatt cacagataaa
    27241 gaacgcaaaa tttatgattt agttgtaaaa cgtttcttag ctgttttatt cccagcattc
    27301 gaatacgaac aactaacatt acgtaccaaa gttggtagtg aaacgttcat tgcacgcgga
    27361 aaaacgattt tacatgctgg ttggaaggaa gtatacgaaa atcgatttga agacgatgat
    27421 gtaactgatg acgtaaaaga gcagcttctg cctcacattg aaaagggcga tacattaact
    27481 gtaaagttac ttatgcaaac atcaggccaa acgaaagcac ctgcacgctt taatgaagca
    27541 actttacttt cagcaatgga gaatcctaca aaatatatgg atacgcaaaa taaacaactt
    27601 gctgatacgt taaaatcgac tggtggatta ggtactgtag cgacacgtgc agatattatc
    27661 gacaaacttt tcaactcttt cttaattgaa aaacgtggta aagatattca cattacatca
    27721 aaaggtcgtc aattacttga tttagtacca gaagaattaa aatcacctac actaactggt
    27781 gagtgggaac aaaaacttga ggcaattgca aaaggcaaac taaagaaaga agtattcatt
    27841 tcggaaatga agaactatac gaaagaaatt gtttctgaaa ttaaatcgag tgataaaaaa
    27901 tataaacatg acaacatttc aacgaagtct tgtccagact gcgggaaacc aatgctagaa
    27961 gtaaacggca aaaagggaaa aatgctcgta tgccaagatc gtgaatgtgg tcatcgtaaa
    28021 aacgtatctc gtacaacaaa cgctcgctgt ccgcaatgta agaagaaact agaattacgt
    28081 ggtgaaggtg caggccaaat tttcgcatgt aaatgtggct atcgtgagaa attatcaaca
    28141 ttccaagagc gacgtaaaaa agaatctgga aacaaagccg ataaacgcga cgttcaaaaa
    28201 tatatgaaac aacagaaaaa agaagaagaa ccattaaata acccgttcgc agacgcatta
    28261 aaaaaattaa aatttgatta aacaaaaagg ttcctacctc tatcggtagg aaccttttat
    28321 tttagtgaat gattttactt ccttttgcat tctcaacaaa tttttcactt gatttgttaa
    28381 ttggtgtttt cagtaataac gcagcaacaa tcataactac tacgaaagca cttaacacaa
    28441 gtaaatctcg cgttacgata tcccaaagca ttccgccaac tgtttcacga attgcgctaa
    28501 ttgcgtatgt gaatggtaag aacggataaa tcgcttggaa gaacgctggt gtcatttgga
    28561 ttgggaatgt tccgcccgat cctgctactt gtagtacaag taaaatgatc gccatcgatt
    28621 tcccaacgtt tccgaaaata gaaacgagtg agtatacgat acaaacgaag actccaccaa
    28681 taaataaact aaataacaca aaccagaact tatcgactac gtacgtaccg agtaagaata
    28741 tatctcccat cgatacgata aacgcttgtg aaagacctat cgttaagaat gttaataaac
    28801 gtccgaagta aatttcatgg ctcttataat tcgcgccctc ttcgtgtact tctaccgtta
    28861 ataatgaaac cattaataat gcgcctaccc ataatgcaag cactgtatag aatggtgaca
    28921 ttgctgaacc gtagttcggc atcgcaaata atttattctc ttttaaattt actggattcg
    28981 caaagtaatc actttgcttt tcaacatcgt ttttcaataa gcgtatgatg tcttttaaat
    29041 cctcttcaga ttcaaaatca cgaattttat ctgctaattc tttaatcttt ttctcagtag
    29101 ctggcatttc agctttaatg tctgctaatt tctttttacc atctactaag ccttttgatg
    29161 aatcttctag taatttttta acatctggaa gctttttgtc tgcctctttt aaaatttgag
    29221 atgtgttttt agacatctct tttgtgcgag caattgctgc attgaaattt ggagtgattt
    29281 ctgagtcata tttagctaaa atgtcaccaa tttggcccga aacactttta gacacttgat
    29341 taatactttc aataacatct gctgctggtt tttgaccttt attaatagcg tcaattcctt
    29401 tatcagttaa atccattcct ttttgcaaac catcttttgc tttatttaac ttagaaattg
    29461 taccattaag gtttttatca ctattcacat cagctaacac tttatttgta ctttccagaa
    29521 ctggaatcat gtcattaact aaattccaac ttgctttgaa ctgcccattc aaatcattta
    29581 aggctacttt tgtagaatct aatccattaa cacctttgtt acttaagtct tctctggctt
    29641 tttcaagctc tgtttttaat ctgctgtaat catttacagc cttatcatat ttttctctac
    29701 cattgtctaa cgcttcattt gtttgattta ctaactcatt tgcttttttt atatcttgat
    29761 ttaaattacc tcttagttgc tgagcatctt cttttacatt ctcagctttg tttttcaatt
    29821 gttcagctgt gcttactgct ttttcgaaat ctgctacaaa atttgtatta taatcttttt
    29881 ctgcttgatt tactaaatta tttactgcat ctaacttttg atttacagca tctcgcacat
    29941 cttgtttaac ttcttggcca gaactaatta aatctcctac atgcttaact ctattgttag
    30001 catccaccat agaattttta agcactgtta aactttccac tctgtttcca aagaactgtt
    30061 taccgaagtc cgttgaagct gcttccttaa acgttgtaaa gaaatcaatc aaatatgaaa
    30121 cgctgtcgat acgctcttgg agcaatttcg aagcatcttg cacatttttc tgtgctacag
    30181 ctggatccac acctttattt tgaagaccat ccataacact ttttacatat gcggttccaa
    30241 cacgagtaga attgaaaaca ttatttacag tttgatcaat atttttagca acatttttat
    30301 acccctcacc attcacctgc ggtaacgctg gaatctctgg tatttgcggt atttgtggaa
    30361 gagttatatt aggtaacact gggaatttag ccggatctgg aagtgccaaa ttgaaatcca
    30421 atgatggatt ctttaagaaa tccgtaattg ccgccgcacc atctaaacct ttttgcatta
    30481 ccattaaatt attcttaata gttcctggag cacgttgcaa tgtttcatca tttctagcaa
    30541 agaatttatc taaattccct aacgcttctt gcccatcatt cataacactc tctacaaccg
    30601 gcaactcttt ttgcgctact ttcacaacat cttctgctcg agttgcatca tctaatgcct
    30661 tatccataag tgtattcatt tctgggaact gcgcttctaa cttaaataca agatctttta
    30721 ctttttcgat acttggtaag tttgtttcta aatcgattcc aaggtcattg aaaattttaa
    30781 aaatctcacc gtttgctgtt tttacaaagt ttttactaat ttcttctgta atacctgatg
    30841 caccttttgc tgtaatcttc ggtgcaatcg cgtttacttt ttcattcaca tagtaatcca
    30901 gttctggttt tttaggattt tcatccagaa cagttgcaat tttttcagag aagtcttttg
    30961 gaatcgtaat acttgcataa taatccccac gctcaactcc gtaaatcgct tgtttttcat
    31021 ccacaaattt ccagccgaga tttttgtttt tcttaaggga gtctacaatc tctttcccga
    31081 tattaatatc tttccctctt aaattagaac ctgcatcttg gttagaaact gcaatgggaa
    31141 cctcttttgt atttccgtac ggatcccaag aagctttaat gttaaaccat gcatataacg
    31201 atggtaaaat cattaatcct aaaacaataa caattgcagc ccaatgtttg gctacattcc
    31261 gtaaatctgt cttataaata cgccaaattt gtttcataga agttatcacc taattatata
    31321 tttttccttc tttagaaaat gatacatgca ttttgcaatt atatcacttt ctacatcgtg
    31381 tattaaccaa aaacgtacta ttttttccca ttaactttca cttactttat tatataacga
    31441 agtgagtcaa agtatgaata caaaatgacc aaatcggttt tacattcaat aataacaaat
    31501 atatatgaaa tgtcataaaa aatacaagta ttttctcttg gaaatacttg tattcctaaa
    31561 aaaaatcctc acagctttta ttctctgtga ggatttcttc tattatatat ccaattgaac
    31621 ctctacaccg aaatgatctg aaattacatt tctgtttgta ccattaaaaa taacttttga
    31681 agaatgaact tttttacttt ggttacacaa tattagatcg attcgcaaat tatgtttatt
    31741 ttcatcccaa ccagcaatct cgccttggac agtcgttcct tcatccttct ctattgctaa
    31801 ttcatatgtg tcatacaacc ctttttgcat catatactca taaccttcgc ctttcaatcg
    31861 agcattgtta ttaaaatccc ccattaagaa ggctagctta ttgctatcta cacgctccat
    31921 caaacgatcg acttgacctt tgaatgactc ttcttcatca ttccaccaac cgagatggca
    31981 agagtaaaac gttatatcct taccattata agcaattgtt gtacttacaa ttttacgcgt
    32041 tttccaatac gttgtatcct cgttttctga aataaagaac gtatcttctt ttataatatt
    32101 atgcttcgtt ataatcgcta atccttcttc gtacacgtca taaccaatat gagagaaatc
    32161 ccaagtaata ttgtaatctt ttacatgtag cgcttttaac tcttctaata gtaaaagtcc
    32221 aaaattatct tctttcttgt taccgcatac attttcagct tgtatggact gacttacttc
    32281 ttgcaatgcg atgacatcgt actcttcttc ttgaattact ttagcaaggt attgtatctt
    32341 ttctatttga ttctcttctt gccaagaatg acagtttaaa gttagcaatt tcatattatt
    32401 acgcacctaa catatcttga atgtctgact ttaatacgtc agctttcgga ccatataccg
    32461 cttgtacacc tttatctttt acaataagcc ctaaagcacc attttgtttc cactgtgctt
    32521 ctggtgcaac aacatctaag tcttttactg ttacacgtaa gcgtgtcata caagcatcta
    32581 cgtcagcaat attttctttt ccacctaata aatcgataac ttttgttgct aatgaaccgt
    32641 cttgtacatt tcctgttcct tctgatgcct catcttcatt atcaatatag ttacctgcac
    32701 gccctggtgt tggtaaattg aattttttaa ttaagaaatt aaatagtgta aagttaagac
    32761 cgaagaacac taatgaaaca ataacaaagt tgattaagtc tcttgttaaa cctgcgttaa
    32821 ccatcattgg tgtacgagta attaactcaa taaatccaaa tgcatgaaca cgtaagttaa
    32881 ttaaatcagc tagtgcgaat gcaagtcctg ttgtaatagc atatacaaca tataatactg
    32941 gagcaataaa catgaacatg aattcaattg gttctgttac acctgttaag aatactgcta
    33001 atgctgctga taaaaacatt ggtttatatt ttgcacgctt ttctttatca acgttacgga
    33061 acatcgcaaa tgcaatcccc attaacgctg ctgttgagcc gataacttgt ccagctttga
    33121 aacgagctgg tacaacgtta tttaataaat cgttatatgc cttcgtatct ccatttgcta
    33181 ataaattatt taaatctgta atccatgcaa gccataatgg atcttgtcct gctacaactt
    33241 gtccaacttt tgaaccagtt agcatcgtat atgttccgcc tagctctgta tagttcatcg
    33301 gaatcgttaa catatggtgt aaaccaaatg gtaataataa acgctctaac gttccatata
    33361 caaacggtgc aacaactggt gcactatctt ttgaagctgc aatccagcga ccaaattcat
    33421 ttaacccact ttggatgaat ggccatagaa gtgataatac aatcgcagta actgtagacc
    33481 aaagaattac aacgaatggt acaaatcgtt ttccattaaa gaatgctaat gcctgtggca
    33541 gtttattata gttataatat ttgttatata aattagctcc taagaaacct gtgataatcc
    33601 ccacgaaaac tcccatgttt aatgctggtg caccaagtac agaagtaaag taatctttta
    33661 caattaaatc tcctgctatt actgaagaaa ctgtcgcttt tgaatccgct aacatttgag
    33721 cgtttacgcc aaatatagct cctgtaattc ggtttgttaa gacgaatgct aatagcgctg
    33781 caaatgcacc acctgcacga tccttcgccc aagatccccc aattgctact gcgaataaga
    33841 tgtgtagatt tgtaatgatt gcccaaccga tgtcttccat tacgcgagca attgtatgaa
    33901 ctgcgttaac atccccagca gacataccaa ttaacttacc gatggaaatc attaaaccag
    33961 ctgctggcat tacggctaca acaactaata acgctttccc gaacttttgc caaaaatcaa
    34021 aagacgtaat tttcatctgt tcttcctccc ctttatttat aacaacataa tgatttaaat
    34081 tataatttct gttcccttta tgaaaacgat tccttgtgtt actttatttt tatctttacg
    34141 caaccgtttt cataaatcta ttttaataaa agcgttttca ctttgcaata gaaatttatt
    34201 ttttttcata aaaaaagatg ctccaagagc atcctttttt attatgaaat gcgataaacc
    34261 cttgtttcat aaggttttaa agcaattgtt tttacttctt catgttcgac aacttcatag
    34321 ttatttaaaa gcaaacgttt gcgttctagt gcaaatgaat cctcattata cactgcttcc
    34381 tcttttgaga tattactaat tacaatgact ttttcatcct gtaacgtacg tgtatatgca
    34441 taaatttgtg gatcgtcttc taaaagtaaa tcgtacgtac catagttcag tacatcgtgc
    34501 tcttttttca gggcaatcat tttcttatag aaattgaaaa tagacttttc ttcatttttt
    34561 tgcttttcaa cattaatttc tttgtaattt ggattcatgc taaaccaagg tgtacttgtt
    34621 gtgaaaccag cattcatctc atcattccac tgcataggtg tacgtgaatt atcgcggcaa
    34681 gaagcccata taatctccat catatcttga tgtggtacgc cctctgcaat tttctcgcga
    34741 tataaatttt taattgctac atcatcgtaa tcttcaatat ttggtaactg aacatttgtc
    34801 ataccaattt cttgtccttg ataaataaac ggtgtaccgt gcataaagaa atacatcgct
    34861 cctagagctg ttgcactttc acgccaatat tgtttatcat ctccccatgt tgaaacgata
    34921 cgtggtttat catgattttc aatatataaa gcattccatc ctttattttc taatcctttt
    34981 tgccatttcg ttaatacttt tttcaatcct acaacatcaa ggtctttctt cttctctgca
    35041 tcccataaac ttaaatgttc aaactggaat accatattga acttaccttg ctcttctcca
    35101 acccaaagct cagcatcttc aatcttaacg ccatttgctt caccaacagt cataatatcg
    35161 tacttagaga atgtattttc ttttagctct tctaataaag gttgaatacc tttcacattc
    35221 atatgtttat caaaagatgg cacatatttt aactcttttg gatttggcat atccttgagg
    35281 ccttcttctt ttttaatatg actgatcgca tcaacgcgga aaccatcaat acctttatca
    35341 agccaccaat taaccgtatc atatagtact tcgcgaactt ctttattctc ccagttcaaa
    35401 tctggttgtt tacgtgagaa taaatgtaaa taatattgtt ctgtttcttc atcatattcc
    35461 catgccgaac cattaaaaat actttcccag ttgtttggct ccgcaccatc tttaccatca
    35521 tgccaaatat accaatcacg cttcggatta tctttagatg aacgtgattc aataaaccat
    35581 ggatgttcat cactcgtatg attaataact aaatcaataa ttagcttcat atcacgctta
    35641 tgaacttcat ctagtaaagc atcaaagtct gccattgtac caaactcatt cataatatct
    35701 tgataatcac taatatcata accattatca tcattaggtg acttatacat tggacaaatc
    35761 caaattacat ctatacctaa atcttttaaa taatccagtt ttgcaataat accttgtaaa
    35821 tctccaatac catcaccatt tgaatccata aagcttcgtg gataaatttg ataagcaacc
    35881 gcttctttcc accatgtctt attcatagtc cttctctcct tttgcatccc atcggaattt
    35941 tttatgcaaa cgttttcgta acactatcat aacaaaatat gaacagtttg caactgtttt
    36001 cattgaactc tatgtagatt ctttattctt atgctttatt tatttctcac aaaggtaaat
    36061 ctcattctcc acctctcctt gtccacgcgt attacagaca tttttcatat attaataaaa
    36121 agctctgatt attttagaaa ggagcaataa attgaagcaa acaaaattaa caggtcgtat
    36181 cgttgttccc acagattcgg actacgacgt agcccgaatg aatttaaatt taagtattcc
    36241 aaaactccct tgtattattg ttttttgtca aaataacaag gatgtctgta acgccttaaa
    36301 atgggcacgt gaacgtcata taccatttcg gttaagaagt ggacgtcata gctatgaaaa
    36361 tttttctctt ttaaatagag gacttattat tgatgtgagt gaaatgcatc gcattactgt
    36421 taatacagag aaattaacag caacaattga ggctggtgca aatcttggca ctgtttataa
    36481 agaactttgg aattacggtg ttacaattcc tgctggtaca agtgcaagcg ttggaattgt
    36541 tggattagca cttggcggtg gtattggtat gctttcgcgc ttatttggat taacatgtga
    36601 tcaattaatg gaagtggaaa tgatacaagc gtgtggaaaa tttggtgcaa aactccttcg
    36661 tgcaaatgaa caagaaaact ctaacctttt ttgggcatgc cgtggtggcg gtggtggaaa
    36721 cttcggaatt gtcacttctt taacttttcg agtccacccg ataaaaaatg tatcaatttt
    36781 ctcaattaca tgggaatggg aagactttat tgctgcattt caagcgtggc aaaactgggc
    36841 accttatata gatgaacgtc tcacttcatc gatcgaatta ttcgccaagc aacgaaataa
    36901 aatcgaagca caaggcgagt ttgtcggttc tccctctgaa cttcattccc tattatcccc
    36961 tcttcttgaa actggtagcc cctctctctt tatagaagaa gttccttata taaaggctgt
    37021 tgaatttttt aatggcggta acatccctga aaatttcaag cgctctggtt cctatgtcta
    37081 taaacctatt ccccttaaag gcattcaaat catgcaatac tttctttctc atgcaccaaa
    37141 taaagatgct agtatttggc atcaatcgct cataggtgct gttgaaaata tttcgccgaa
    37201 tgaaacggct tattttcatc gtaaagcaat tattgctcaa gaatacatta cctcttggaa
    37261 atgcgatgat gaagaaaatc gaaatatacg ctgggttaaa gatttacgag aaagcttaga
    37321 tccttataca ctcggtgact atgtgaactg gcccgatatc gacattaaaa attggcaaac
    37381 tagttattat ggctctaact ttcacagatt gcgtaaagta aaaactatgt atgatccttg
    37441 tgatgttttt catttccaac aaagtattcc tctttttcat acgtgaaaaa ggggataaca
    37501 taaaaaaatc atccaatata ccgttacctc gcagtatgtt ggatgattca agttgatttt
    37561 ctatatcgtt ccaaattatt gctcctactc ataagctttt acttacagat taattgtatt
    37621 tcgtatcatt ttcatgcaat gaatgtaatt taatatttgg tactttatct ttttccatac
    37681 ctctattata agaaacagga acttgaaatt cgaattgctt tgtctcatgt ttttgtaaat
    37741 agactggttt cggtactgga tagctttttg aattctcgtt tgcattatca tataaaacaa
    37801 cttctaatgc ttgtgaatga ttacgataat tttttaaagt aacaatgcac ttagattcga
    37861 taccctctcc attttcctcc attctacact ggctatcttc ttttttatat tctattgctt
    37921 ctacccctgt ttttcctgcg tagtaccatg ttttattcaa tgtctggagg attgtattta
    37981 aaataaacgg catcattaca atcaaaatac taatgcctac tacttttatc ttattcattt
    38041 ttctaaatgt actagactcc ttttttccta gccattttaa aaataatata aatgcaatta
    38101 catgtagtat gaaagaaaca atcaatatat ttgagacttt ataatccata taaacatacg
    38161 tatgtatcgg aaccttatag acattgaata gtttttcccc aattaattca ttatcatttg
    38221 gaatttttaa taataacaaa acccctatac tgtaacaaat agctactaat cgatcatact
    38281 caatacgaat cattctttct ccccttcact ttgtttttta ttatcgattt tagctattat
    38341 taccatacta tacaatcttt ttatagagga taacgtaaaa aagttcctta taaatatata
    38401 aagaacctta ttaatataca ttatgaatta aaaaatcaat atacagtttt cacatagaga
    38461 tttcttcaaa atatgttgga ttgtgtattg taattttttt atctaaaatt gtaacaatgc
    38521 tatcattttt taattgtttt aatacgctgc taactgtctc tcgagatgtt ccagatattt
    38581 tggatatttc aattgttgta agtggacatg aaattacaat cttttcccca ctctgttctc
    38641 ctaaatcctg cattaaataa tttaacgttt ggataacacg atcttgtgca ttaggaattg
    38701 taatattttg cactcgattt tcgttcaatt ttaatataga tgataattgc tgaacaacgt
    38761 acatcaattg cgttctgctg gattttacca tatcttcaaa gattaccgtt ggaatataat
    38821 atacctccac atccgtcatt gcttctgctg tatagttata tcctctgtct gtaaacatac
    38881 caccataagg aaaaatagaa taccgcttta catagtcatc gtataataag ttaccatttt
    38941 gattaacccg ctctaacttt acaaaaccat ctaacatgaa gtaaattctt tcccttgaat
    39001 ccccttctaa aaataaaaat tgaccttttt tataagttcg ccaataaaca aactctgtta
    39061 agcctttcaa ttttttttct gttaaatgag caaataattc gaactgcttt aagtctttca
    39121 ctacgttccg tctattcata aaattccctc tctcttgctg tatgttggag cgaaaaatca
    39181 agaaagcgta ttcaatttga attttatcat aattaactta tatattcaga tttcatcatg
    39241 aaaactttat gaacaatgag tacaaaaaat attaataaat aaaaagaatg aagttattaa
    39301 cctcattctt tttttactac taagtagcgt acataataat ttaaacatac atgcatacat
    39361 tctgttttga aataatagta ccggcttttt cttctagtgc ttcatatact ttttctaaag
    39421 acgtaataat tgtttttctt tttggatttg tattaacaaa attaatagca gcttcaattt
    39481 ttggaagcat gcttcccgca gcaaattgtt gttcttcaat atattcttct aattgattta
    39541 ctgtgacatg ctctaatttt ttttgattcg gttgattata atttacatac acataatcaa
    39601 ctgcagttaa aataacgagc gtatcggcat ctactaattc tgctaatttc tgcgcagcga
    39661 aatctttatc gataaccgct tcagttcctt ttaacccttc ttcggaatca attactggaa
    39721 ttccacctcc gccaacagct atcactatgt ttccatcttc gaccaaagaa ttaataactt
    39781 tatgttcata aatacttaca ggcttcggtg atggaacaac acgtctccat cctctaccag
    39841 catcttcttt aaacactgct ttcgtttcat ccattaatct tctggcctct tcttctgtat
    39901 aaaaaggacc aattggttta gttggatttt taaatgcctc atctttttta tccacaacaa
    39961 cgcgcgttat aaccgttgct acatctttgt ttatattacg ctttttcaat gccttttcga
    40021 ttgcattttc catccaatat ccaatcatcc cttggctcat tgccccacaa gtatctaatg
    40081 gcattgcagg tgtcttttcc gtttctgcag ctttttgctg taataaaata ttccccactt
    40141 gtgggccatt tccatgcgca attactatat ccacatcatt ttccattatt ttcacaagtt
    40201 gttccgccgt tttttccaac gcttcttgct gcgctcccgc agtagcctct c
//
