LOCUS       NZ_NTSF01000026        21370 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS021634
            AFS021634_110_H4_Contig26_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTSF01000026
VERSION     NZ_NTSF01000026.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 45260)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 45260)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.88x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563165.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 02:22:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,903
            CDSs (total)                      :: 5,824
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 84 of 212
            Pseudo Genes (incomplete)         :: 133 of 212
            Pseudo Genes (internal stop)      :: 67 of 212
            Pseudo Genes (multiple problems)  :: 60 of 212
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:49:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 21370
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTSF01000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21370
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     gene            <1..1224
                     /locus_tag="CN325_RS21795"
                     /old_locus_tag="CN325_21800"
                     /pseudo=""
     CDS             <1..1224
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN325_RS21795"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CN325_21800"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="QQETGHGRLQKQSSKLSQHINQEFQQPESTAKVLNKKQETAEQKQ
                     VLQTINVTESPPEKRQGKLQTQSSKVLQHSNQEFQQQESTVQRVDRHSKTSKQKQFSQT
                     TSALQSPQETGQEKLQKQSSKQSQHINQKIRQQDLIKEVQKPKAVKTSQQKQLEQTEKS
                     LLKESEKKFKKLLTDNPKVQKGIHFIGKLGKDSLIATKAEVKNSLIEAKNTLKYGTKTL
                     AGATKNSVKGGIKKYQKALEQGDDGVKVASQGVTKGYRLTRKGFRLAKKGVRKLRKKRQ
                     EKLYIKTLDKGKIESLKKLKKLEKKPSVKKLTKATVKKLTKVTTNVAGSSALKYQEQLE
                     KGDEGVKLASQSATKIARATKKLAKNRIKANAKLGKMGKQQSKLIPFPKDTKLKVESKT
                     NLKKKVTW"
     cand_cluster    1..21370
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21370
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3553:11370](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3554..11370)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            1522..1863
                     /locus_tag="CN325_RS21800"
                     /old_locus_tag="CN325_21805"
     CDS             1522..1863
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087612.1"
                     /locus_tag="CN325_RS21800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21805"
                     /product="hypothetical protein"
                     /protein_id="WP_098391610.1"
                     /transl_table=11
                     /translation="MRSIKSILLISIIVVIVSVFLFQYFVSSTSTAAIVTVLEKGYSME
                     DGAAWIKIIPPNSPTEIQNEYKVTVKVKEPSVWNLIEKDQIYLVNYIEKHNIKTLDYIK
                     KSGDNQAIP"
     gene            2213..2545
                     /locus_tag="CN325_RS21805"
                     /old_locus_tag="CN325_21810"
     CDS             2213..2545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002049918.1"
                     /locus_tag="CN325_RS21805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21810"
                     /product="hypothetical protein"
                     /protein_id="WP_098391611.1"
                     /transl_table=11
                     /translation="MISKIKYLETNSVAEGTIKDYGQDAKNVFQKLISSETAVSKIAIW
                     KKKLFENYSNLSQRTIEFSLDNKEKITFEILTFNVEAHKNESYIQHTGGSTIYHLNAER
                     TEDILV"
     gene            2787..3023
                     /locus_tag="CN325_RS21810"
                     /old_locus_tag="CN325_21815"
     CDS             2787..3023
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659766.1"
                     /locus_tag="CN325_RS21810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21815"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_098391612.1"
                     /transl_table=11
                     /translation="MKEKHEDSITNKVYEYRVLKRMSQKDLADAVGVSKQTIFVMEKNN
                     YSPSLVLAYRIANYFEVDINEIFSYVGKEDNND"
     gene            3016..3345
                     /locus_tag="CN325_RS21815"
                     /old_locus_tag="CN325_21820"
     CDS             3016..3345
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566267.1"
                     /locus_tag="CN325_RS21815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21820"
                     /product="6-aminohexanoate hydrolase"
                     /protein_id="WP_098391613.1"
                     /transl_table=11
                     /translation="MIDVLNRWMLESITNFNAVVTFIVVLFLFSAIVLFIMIKKIGQSD
                     ERTKTIYFKVTSCMFKTQIIMNCIFISLVNNDIIYFRQIFILFEAIVFFVGAIYALRIY
                     RKEFK"
     gene            complement(3554..6262)
                     /locus_tag="CN325_RS21820"
                     /old_locus_tag="CN325_21825"
     CDS             complement(3554..6262)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="CN325_RS21820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21825"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_098391614.1"
                     /sec_met_domain="DUF4135 (E-value: 8.1e-48, bitscore:
                     155.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.2e-47, bitscore:
                     151.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTIDSTNLISAVVHRQDNSLKWLSKKHKFSFVWTNIVEYLVSNK
                     HDLSHKEMKIFKSNINSLYSSCMSLVTPTMTFHLNTLYQQNQENIDANFQTFYKEFQDT
                     FISDYTLREDVFSTYPELFRLIYNFFDQSIHNIKESIHLVDVHYEELKNRFDIEEFGEL
                     SVILGEGDIHKAGKSTSRVSIGGKTLFLKWRECSFEKNFIQFQHKFLKNMGIINRINDL
                     REVKGSNYYFQESIEPEGIFEEEHNDHYYQLGAFIFIAYLMGVTDLHYENIIIANGSII
                     AIDCETIATSIDREIAEYIDYDLAKSVYSTYILPFNTVKGAVISGISSLSSQTMYVNDY
                     KINITNRGIDLVNRPLRTISNLNSKKDKSLYFLHTNEIIKGFEESYVEFLKNKNQYVDL
                     LQTMLANKKHRVLKKNTYDYNTLLWESYHPYLMTSYEERYKFFEKNSLLDKDEQILLYN
                     NEIPYIEEFINIQEKYFDRFSYDDLKRQKVLIKESLAFDKVMYLTSNEKNNLLVGPTIG
                     DYEIDKYKDYLLSNSIVDNWITSIETGVTHEDTEYKEMELNIMPDTLYLGKSGVIKFLW
                     AYYDRKPNKQEEIWFKNVLKSFWIKLKKHIITNPKIQTGFYDGIGGLLHTMYLANKKYS
                     IFHDKELIQILMVIKKNISYDTQFDIISGSAGLLNALIDIYHDSSSDDLKKQLLDCVNG
                     VETHLINHFDDINCGWAFENPSDPNDTFYYYGYSHGLSGIIPQLYRSFLITNNDEIKQL
                     VDKSVKKIIMLYDNIERNWPTSSSVDTYYTNWCHGSPGVIYGLGILLKNGYVSKEINNI
                     IYEVLLRLVREEKPNLCLCHGSYGNDIIGKYCSEIIGNNKLKTDFERKLDNNWSKLLNT
                     DNIIEVNKSYMTGITGIYYWKLNNNNLDHIL"
     gene            complement(6259..8397)
                     /locus_tag="CN325_RS21825"
                     /old_locus_tag="CN325_21830"
     CDS             complement(6259..8397)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="CN325_RS21825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21830"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_098391615.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-34, bitscore:
                     110.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKVPYVGQVQESECGLCCVSMLMGYYKQFIPVKTLSKTIEVGR
                     DGVHIKKLGEVLDSFGYNVSYYEADSTSLIQIADKPLILFWNKNHYVVLEKIKNGMFYI
                     VDPNFGRGKLTLEEFNEHFSNIVLLAEPTEATKKINLKENPFKMYIDYFKGKYWDLISL
                     LICSILSTATVLLVSIFMKNLIDRTTASSNSILNSNMVIGLLGLMIMFLVFDLLKSNLV
                     IIFSAKLDKSIYTSVINKLFRVPYKFYLTRSSSDILFRLSLLKSNRDFFIETLIKSILD
                     VGMLVFVLIFMLYIDPILCVSLIIISIVLGLFLYFIRKLIILKNKEEIIEGTKLQGKEY
                     ETLLAISYLKSTGQEEYVKSLLLNQYDVALNKYKEKSFIDNIYGNITKFVSYFAPLLMF
                     FLVLSLYQQSILSLGTVMLVYSISNYYFTSLNGVYSSFNVYGTLQNNLERIVDILEEQE
                     DHYFIKEGTITVDEIKTISFNNVSFRYPGQTDCVIKNLTFTVNKGEKVAIVGETGSGKS
                     TITGLLLGLFIPEKGTIKINGINIEDVNRESLKSLLGYVPQSPNIFNKSIKENILMNRD
                     INENQLIESAERASISNDIEKMPMKYETVISEMGSNLSGGQKQRIVLARAIIDNPDLLI
                     LDEATSAVDNVTEAFISQFLQQANMTQIIIAHRLSTIIEADKVIVLQEGEITNIGTHSE
                     LLNKSDLYKQMYDRELNS"
     gene            complement(8671..11370)
                     /gene="lanM"
                     /locus_tag="CN325_RS21830"
                     /old_locus_tag="CN325_21835"
     CDS             complement(8671..11370)
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CN325_RS21830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21835"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_176528010.1"
                     /sec_met_domain="DUF4135 (E-value: 4.3e-63, bitscore:
                     205.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-30, bitscore:
                     97.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNFYDLVVKFITTYLEGKEIKLVNTTYNKLEVEKELEDTIINN
                     LYPLVEDSFLIDFQLWKEKGISPEESSINTYYELISEEFIGDFFSRFKELEHMLNKRVI
                     YFEKYINKILLDLETFKNDFYFTYLKSISLDAGDSHAEGKSVCIINLDDTRYIYKPRMA
                     ELDQRFMKLIQSQIREYDFTIYSYDTFSIHELIVYKSPESIEDIEKYYYNIGVISAIMY
                     AFKSTDMHYENVIVSNRVPFFVDLETLVGVKRFKEDNPVLAFLDYTTDSVLDTMIYPTY
                     MRESDLNISALTGGAAVYNDFHYTQKVIVDYNSDSVRYEEAPIVIEDKLNRIYSKDKIV
                     HPIDYLECIKDGFKSMSEKMWKNKKYFTNAFLEVIEGNFVRQVLRPTHVYAKFLTTSYE
                     AYYMQKDTYRAELFNILLSNNENDDKQKAVAEEEVGTLLNGDIPIFYAYFNDRHLYNHK
                     GEIVCEDYFLSSSKDMIMNRIEEYSEQEMNRQIYHIESSLFISAYNNKSDDPVLSQSQS
                     SKEMYGEAQVISDLKEFSELIVDRGGYFVSLLPSHAGDKCKLSSINSSLYEYGGTILLM
                     SHFRDELELSVDYFKKIISSIKSSKLHFPELLDAFTGIGSYIYINYLLFKNTSETFFIE
                     EVNDCYKLLKIDFSKEYKIDYITGLSGISVLLANLLLDDSIYLSNKFKDASKLFLEDYY
                     VYLSKALNSVTIGAGFAHGYSGIILGLSSANVILKNIEINKLVNQLIEKEELLYVEEKN
                     NYLDPRDNALTTNYYCYGLPGILLSKIQLIKIGECVDLKDLNKKLTGLCNAIINNELEL
                     DKLGYCLCHGIGSFMEIIEEAYKEGLISHTLYIEVQTILMEKLNSNTNGLLTSNNLYGF
                     MMGKGSKVYSYLRYVNKDIPAMSLLNVN"
     gene            11509..11700
                     /locus_tag="CN325_RS21835"
                     /old_locus_tag="CN325_21840"
     CDS             11509..11700
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="CN325_RS21835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21840"
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="WP_098391617.1"
                     /sec_met_domain="mature_ha (E-value: 2.5e-11, bitscore:
                     34.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKLKKESISELAKESYLNQLDKNNKRLENSFGADCNFWNISCHL
                     GNDGSVCTLTKECRPACW"
     CDS_motif       11509..11610
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MFKLKKESISELAKESYLNQLDKNNKRLENSFGA"
                     /locus_tag="CN325_RS21835_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       11611..11700
                     /prepeptide="core"
                     /locus_tag="CN325_RS21835_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3201.6"
                     /monoisotopic_mass="3199.4"
                     /core_sequence="DCNFWNISCHLGNDGSVCTLTKECRPACW"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFKLKKESISELAKESYLNQLDKNNKRLENSFGA"
                     /leader_location="[11508:11610](+)"
     gene            11728..11907
                     /locus_tag="CN325_RS21840"
                     /old_locus_tag="CN325_21845"
     CDS             11728..11907
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="CN325_RS21840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21845"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_098391618.1"
                     /transl_table=11
                     /translation="MKELKKNIESEKVLKKLTEVPDLTGGTSTTVPCGIGSTITISIAY
                     CPTSKCTERCGTRG"
     CDS_motif       11728..11805
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKELKKNIESEKVLKKLTEVPDLTGG"
                     /locus_tag="CN325_RS21840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       11806..11907
                     /prepeptide="core"
                     /locus_tag="CN325_RS21840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.80"
                     /molecular_weight="3149.6"
                     /monoisotopic_mass="3147.6"
                     /core_sequence="TSTTVPCGIGSTITISIAYCPTSKCTERCGTRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKELKKNIESEKVLKKLTEVPDLTGG"
                     /leader_location="[11727:11805](+)"
                     /alternative_weights="3167.6"
                     /alternative_weights="3185.6"
                     /alternative_weights="3203.7"
                     /alternative_weights="3221.7"
                     /alternative_weights="3239.7"
                     /alternative_weights="3257.7"
                     /alternative_weights="3275.7"
                     /alternative_weights="3293.8"
     gene            12169..12363
                     /locus_tag="CN325_RS21845"
                     /old_locus_tag="CN325_21850"
     CDS             12169..12363
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="CN325_RS21845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21850"
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="WP_098391619.1"
                     /sec_met_domain="mature_ha (E-value: 5.6e-11, bitscore:
                     33.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKLKKENISELAKESYLNQLDKNNTRLENSFGADCSWWNVSCHL
                     GNDGKYCTASKECMPTCND"
     CDS_motif       12169..12270
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MFKLKKENISELAKESYLNQLDKNNTRLENSFGA"
                     /locus_tag="CN325_RS21845_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12271..12363
                     /prepeptide="core"
                     /locus_tag="CN325_RS21845_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3278.6"
                     /monoisotopic_mass="3276.3"
                     /core_sequence="DCSWWNVSCHLGNDGKYCTASKECMPTCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MFKLKKENISELAKESYLNQLDKNNTRLENSFGA"
                     /leader_location="[12168:12270](+)"
     gene            12387..12557
                     /locus_tag="CN325_RS31015"
     CDS             12387..12557
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="CN325_RS31015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_176528011.1"
                     /transl_table=11
                     /translation="MKELKKNIESEKVLKKLTESPDLSGGTTIPCGELAVVITAAFCPT
                     SKCTTRCGSRG"
     CDS_motif       12387..12506
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKELKKNIESEKVLKKLTESPDLSGGTTIPCGELAVVITA"
                     /locus_tag="CN325_RS31015_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12507..12557
                     /prepeptide="core"
                     /locus_tag="CN325_RS31015_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.40"
                     /molecular_weight="1584.8"
                     /monoisotopic_mass="1583.7"
                     /core_sequence="AFCPTSKCTTRCGSRG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKELKKNIESEKVLKKLTESPDLSGGTTIPCGELAVVITA"
                     /leader_location="[12386:12506](+)"
                     /alternative_weights="1602.8"
                     /alternative_weights="1620.9"
     gene            12855..13772
                     /locus_tag="CN325_RS21850"
                     /old_locus_tag="CN325_21855"
     CDS             12855..13772
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019377256.1"
                     /locus_tag="CN325_RS21850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21855"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098391620.1"
                     /transl_table=11
                     /translation="MCNYIIKTVNLTKEFKSKPVIKNLNFTLKKGEICAIIGKNGAGKS
                     TFFKMLSNQVLPTEGLIQLDNQEDKDLDLSRKKFSFLIEAPAFFDNFTAKQNLEYYRIQ
                     RGIDNKKLIDELIRMVKLEEHTKVTFSNYSMGMKQRLGIALCLLSNPDCLVLDEPTNGL
                     DAEGIRELRQLLINLNKEKNTTILISSHVLSELQNIATRYVFLDKGKIIEDINANDFEK
                     KSSQHLKIKVNDTSLAIDLLKQFERNLQCDILEDNWIIVKNNITDGSNINAFLTKNNII
                     VYEFKVEHHNLEGYFFNLLGGDLT"
     gene            13769..14518
                     /locus_tag="CN325_RS21855"
                     /old_locus_tag="CN325_21860"
     CDS             13769..14518
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN325_RS21855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CN325_21860"
                     /product="hypothetical protein"
                     /protein_id="WP_098391621.1"
                     /transl_table=11
                     /translation="MINYIKSEFYRFQRSKLFFATTGISLSLVILASIALFYSLKADET
                     FKYANLEFYFANIISFYIVIIFLAYAISSILAGKDLTIIRQSISFGISRKTIFFGKLIV
                     SLSYFLILGITLVISSMIIGNLLLEHHINSIFSDYLLALTNMLPLIVSSFILAYIIHIL
                     AIKDIANIAILILIYSISGDIIKFISKSLPFISDSYKYFPSSILSTNFTNFASHKGVFL
                     IEAWVVGILLSIIYLIIGVFLFSKKDL"
     gene            15130..16005
                     /locus_tag="CN325_RS30655"
     CDS             15130..16005
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022240.4"
                     /locus_tag="CN325_RS30655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2599 domain-containing protein"
                     /protein_id="WP_141534859.1"
                     /transl_table=11
                     /translation="MNDKLKKLIISGTLAGTVFNITNVVSADSTDISGKATYTNAMSSD
                     YIQGNLTFSTANGEIIKIGPLQSINPKNNSFYFFSNKKDSLPIFKKVENGVEQSIKIDP
                     TKTNGKYKVPFDFGNGESIKVEEDGSAVIYNKNKESIAVVMPTEAKSQSGENLEVNTTL
                     KNENTLEYYVNIKEEVNPVTIKNTTTSYAFSQYFSSGNWIVRDGMVSLSLEPTSALTKL
                     IVNRAIRTDSWNKVKDTFSMDDQWSNTSSMQNQYLCHYDFAKSFKTPWNLEPHRPDVGY
                     LKTVAATCNP"
     gene            complement(16157..16396)
                     /locus_tag="CN325_RS31455"
                     /old_locus_tag="CN325_21870"
                     /pseudo=""
     CDS             complement(16157..16396)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016136472.1"
                     /locus_tag="CN325_RS31455"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21870"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDETRSKLYEVLEANTTITRLRVITFITITWIKLSTFMLELQMTQ
                     LLRSLYISSLRCLQGTRNLLKPQIKKIYKERFVK"
     misc_feature    16637..16654
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.83"
                     /tool="antismash"
     gene            17421..17894
                     /locus_tag="CN325_RS21870"
                     /old_locus_tag="CN325_21875"
     CDS             17421..17894
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016081630.1"
                     /locus_tag="CN325_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21875"
                     /product="hypothetical protein"
                     /protein_id="WP_141534860.1"
                     /transl_table=11
                     /translation="MDDRSSRQWKMRQKLRELKIKNRIDTNPLFNECLESLGNETLISS
                     REKSQQIATTLMNLFPITFSGRIDWKQIDNQLIASHKEQLISLIRAHQLNFDGQIFIIW
                     DNYEIPVVSTNLDTVFQSLVDVDAVSFYYWLLDKEYKFVIEIIDEELIKVEFR"
     gene            complement(18196..18465)
                     /locus_tag="CN325_RS31460"
                     /old_locus_tag="CN325_21880"
                     /pseudo=""
     CDS             complement(18196..18465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811979.1"
                     /locus_tag="CN325_RS31460"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CN325_21880"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNQLKLEGVIGGGGVIILKQIP"
     gene            complement(18714..20027)
                     /locus_tag="CN325_RS21880"
                     /old_locus_tag="CN325_21885"
     CDS             complement(18714..20027)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402254.1"
                     /locus_tag="CN325_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21885"
                     /product="hemolysin family protein"
                     /protein_id="WP_098391623.1"
                     /transl_table=11
                     /translation="MNILSLIMVVVLIAFTAFFVAIEFAIVKIRGSKIDQFVLEGKKGA
                     LAAKKVTTNLDEYLSACQLGITVTAMGLGALGEPTIERLLHPLFDKVNINPSMASLLSL
                     GIAFTIMTYLHVVVGELAPKTFAIQKAEKITLLLSPPLIWFYKIMYPFIRLLNGSARMI
                     TGLFGLKPASEHDVAHTEEELRLILSESYERGEINQAEYKYVNNIFEFDNRIAKEIMVP
                     RTEIIGLHVDNSLADHIKIIRHEKYTRYPVFGEDKDEIIGMVNVKDFFIRYINKETKES
                     DSIHLYTRPVIEAIESIPIHDLLLQMQKKRIPLAVLHDEYGGTAGIVTIEDILEEIVGE
                     IRDEYDEDERPPIQQMNEYHFIVEGKVLISELNDLLGLHMNDEDVDTIGGWIMMQNYDI
                     EEGQTIKSEEYEFKILSKYAHQIKSVEIKKEIEQAATV"
     gene            complement(20445..20900)
                     /locus_tag="CN325_RS21885"
                     /old_locus_tag="CN325_21890"
     CDS             complement(20445..20900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002090658.1"
                     /locus_tag="CN325_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21890"
                     /product="hypothetical protein"
                     /protein_id="WP_069355900.1"
                     /transl_table=11
                     /translation="MTKLLKLYLFGKGTSVDEREQNTAFEIMANAGILSSIICFGAIIY
                     DVILNKEVTSLGTLSLIILLITSCYIFIMMRIKKVYLRYTSNKTLIRNSIISGFMFYVL
                     YTLLPHLSGEPITMRDLTGNIIWGGLFGLCMYGFGKYNSKKAEEDEL"
     gene            complement(20900..21094)
                     /locus_tag="CN325_RS21890"
                     /old_locus_tag="CN325_21895"
     CDS             complement(20900..21094)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956453.1"
                     /locus_tag="CN325_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_21895"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000956453.1"
                     /transl_table=11
                     /translation="MLTKVKRIRLEKGMTQGELAKLTNVSRQTIGLIEKGEYNPSLKLC
                     IEICKSLGVTLNDLFWEED"
ORIGIN
        1 caacaagaga caggacacgg aaggctacaa aaacaatctt ccaagctgtc tcaacacatc
       61 aaccaagaat tccagcaacc agaaagtacc gcaaaggtac taaataagaa acaggaaaca
      121 gccgagcaaa aacaagtttt acaaactata aatgttactg agagcccacc agaaaaaagg
      181 caaggaaagt tgcaaacgca atcttctaaa gtattgcaac acagcaacca agaatttcaa
      241 caacaagaaa gtacggtaca gagggtagat aggcactcta aaacatctaa acagaaacaa
      301 ttttcacaga ctacaagtgc tctccaaagc ccacaagaaa cagggcaaga gaaattacaa
      361 aagcaatctt ctaaacagtc tcaacatatt aatcaaaaga ttcgacaaca agatctaatc
      421 aaagaagttc agaaaccaaa ggcagtaaaa acatctcaac aaaagcaatt agagcaaact
      481 gaaaaatcac ttttaaaaga aagcgaaaaa aagttcaaaa aattattaac tgataatcca
      541 aaagttcaaa agggaataca ttttattgga aaactcggta aagattcctt gattgctaca
      601 aaggctgaag ttaaaaattc tttaatagag gccaaaaaca ccttgaaata tggtactaaa
      661 actcttgcag gtgctacaaa aaactctgta aaaggtggta ttaaaaagta tcaaaaagca
      721 ttagaacaag gtgatgatgg cgttaaggta gccagtcaag gggttactaa aggttataga
      781 ttaaccagga aagggtttag attagccaaa aagggtgttc gaaaattaag gaaaaaaagg
      841 caagaaaaac tttatataaa aacacttgat aaagggaaaa ttgaaagcct caaaaaatta
      901 aaaaagctag agaaaaagcc tagcgtaaaa aaactaacga aagcaacagt aaaaaagtta
      961 acgaaagtaa caacaaatgt agcaggaagt agcgctttaa agtatcaaga acaactagaa
     1021 aaaggtgacg agggcgtaaa attagcgagt caaagtgcca cgaaaattgc tagagctaca
     1081 aaaaagctcg ctaaaaatag aattaaagca aatgcgaaat tagggaaaat gggtaagcaa
     1141 caaagcaagc taataccttt ccctaaagat acaaagctca aagtagagtc taagactaac
     1201 ctaaagaaaa aagtaacttg gtaaatacac catatttctt tttcatttaa ttgaaagtaa
     1261 agaaagagtc ataatccaac ataactccta ttcttttata agtattaaga aataaccaat
     1321 tgtcttagac aaacaaagaa tctagtcagc tgctacctga aaacaagttt tttgtgctag
     1381 catagtattt cttaaaaacg gggtgatgta cggaatggaa tcgtcttatt ccattccagg
     1441 accatattgt taagtattat ttttcatgaa tacagtattt aaactgatag ggaagagtaa
     1501 atactaaatt aggagggctt tatgcgtagc ataaagagta tactgctcat ttcaattatt
     1561 gttgttattg taagtgtatt tctttttcag tactttgttt catcaacttc aactgcagca
     1621 atcgttactg ttttggagaa aggatattct atggaagatg gagcggcatg gattaaaatt
     1681 attcctccca attcgcctac tgaaattcaa aatgaatata aagttacagt aaaggtaaaa
     1741 gagccctcgg tatggaattt aattgaaaaa gaccaaatat acttagtgaa ttatatagag
     1801 aaacataata taaaaacctt ggattatatt aaaaaaagtg gtgataacca agcaattcca
     1861 tagtagttat ctctacaatt gggcacttta atggagtaac gaaaaggtcc ataatcgtat
     1921 ttccctaatg ttccccctta agtaaacggg gggacatttt taacttttta acagtcctaa
     1981 taaaatattt ctgattaaac tttattttaa agccacaact aatccatgaa agatgattga
     2041 tgttaaatca tcttttattt agaggtttac tttcaatatt attgtaaaca caacaatata
     2101 tcgtaataaa aaaacttatg aaacgtttaa aaatatactt aggactatta tttatagtcc
     2161 taagtatatt tttttaatag aacctaaaga taaaataaaa ctaactcctg gtatgatatc
     2221 aaaaataaaa tatctagaaa caaattcggt tgctgaaggt actattaaag actatggtca
     2281 agatgcaaaa aatgtatttc aaaaactaat aagttcagaa acagctgtat caaaaatagc
     2341 tatttggaaa aagaagcttt tcgaaaacta ttctaatcta tctcagcgta ctattgagtt
     2401 ttcattagat aataaggaaa agattacatt tgaaatatta acttttaatg tagaggcgca
     2461 taaaaacgaa tcctatattc aacatacagg gggttctact atttatcact taaatgcaga
     2521 gcgtactgaa gatatactag tgtaatttac taatcgataa tatttcttta ttgctaagat
     2581 catacttcta aacacatcca ttaacatcat cttgaaaagc acttgtgaaa ttatcaaaat
     2641 tgcttttttt ataatttgaa agtaaacttt cgaattatat attatttctt ttaattcata
     2701 taaaaatttt tatcttttgt ataattaaac tttacttttt tataaaaaag gtttaatata
     2761 agtcttaaga aaggaaggtg ttacctatga aggaaaaaca tgaagactct ataacaaata
     2821 aagtctatga atatagagta ttaaaaagaa tgtcacaaaa agatttagct gatgctgttg
     2881 gagtttctaa acaaacgata tttgttatgg aaaaaaataa ttattcccct tcactggtgt
     2941 tagcatatcg aatagcaaat tattttgagg ttgatataaa cgaaatattc tcttatgtag
     3001 gaaaggaaga taataatgat tgatgtatta aacagatgga tgttagagag cataaccaat
     3061 ttcaatgctg ttgtaacatt tatagtagtt ctatttttat tttcagcaat tgtacttttt
     3121 attatgataa aaaaaattgg tcaatcagat gaaagaacaa agactattta ttttaaagtt
     3181 acttcttgta tgtttaagac tcaaattata atgaattgca tatttatttc tttggttaat
     3241 aacgatatta tttatttccg tcaaattttt atattatttg aagccattgt attctttgtc
     3301 ggagctatat atgctcttag aatatataga aaagaattta aataattcac ttataaaaaa
     3361 tgaaggagaa aaggtcagaa ctttccccct aaagagtaca cccgtaccag gcggactaaa
     3421 aaaggtagag cttctacttg ctctaccttt tactcctcat gatatagaat cttaatttaa
     3481 cacgccatgc ctttttatta ttgtgaatcc ccttttcaaa aaaacattgc tacctatcgc
     3541 caaccatatt tcatcaaagt atgtgatcca aattgttatt atttaatttc caataatata
     3601 ttcctgttat tcctgtcata taagatttat ttacttcaat gatattatct gtgtttagaa
     3661 gtttcgacca attattatct aattttcttt caaaatctgt ttttaattta ttattcccga
     3721 ttatctcaga acaatatttt ccaattatat catttccata agaaccatga cataggcaaa
     3781 gattgggttt ttcttctctc actaatctca ataaaacttc atatatgatg ttatttattt
     3841 ccttagatac atatccattt ttcaataaaa ttcccaatcc ataaatcacc cctggcgaac
     3901 catgacacca attagtataa tatgtatcta ctgagctaga tgtaggccaa tttctttcaa
     3961 tattgtcata taacatgatg atttttttta ctgatttatc aactaattgt tttatttcat
     4021 cattatttgt aatcaaaaag cttctgtata attgaggaat tatccccgat aatccgtgtg
     4081 agtatccata ataataaaat gtatcattag gatcagaagg attttcgaat gcccacccac
     4141 agtttatatc atcaaaatga ttaatcagat gggtttcaac accattaacg caatcaagta
     4201 attgtttttt caaatcatca ctactgctat catgataaat atctatgaga gcattcaaca
     4261 atcctgcact tcctgaaata atatcaaatt gagtatcata tgaaatattc ttttttatta
     4321 ccataagtat ttgtattaat tctttatcat gaaatatact atacttttta tttgcaagat
     4381 acatagtatg aagtaatcca cctataccat catagaatcc agtttgtatt ttaggatttg
     4441 ttataatatg cttctttaat ttaatccaaa atgacttgag tacattctta aaccatattt
     4501 cttcttgctt attcggtttt ctatcgtaat atgcccataa aaatttaata acaccggatt
     4561 tccctagata taatgtatcc ggcattatgt taagttccat ttctttatat tcagtatcct
     4621 catgcgtaac accagtttca atggaagtta tccaattatc aacaatacta tttgacaaaa
     4681 gataatcttt atatttatct atttcataat ccccaatagt aggtcccact aataaattat
     4741 ttttctcatt tgatgttaaa tacattactt tatcaaatgc tagagattct tttatcaata
     4801 ccttctgtct ctttaagtca tcataagaaa acctatcaaa atacttctct tgaatattaa
     4861 taaattcctc aatataaggg atttcattat tataaagtaa gatttgttca tccttatcca
     4921 ataatgaatt tttttcaaaa aatttatatc tttcctcata actcgtcatt aaatacggat
     4981 ggtaactttc ccataacagt gtgttataat catacgtatt tttctttaat accctatgct
     5041 tcttgttagc caacatcgtt tgcaataaat ctacatattg atttttattt tttaaaaatt
     5101 caacatacga ttcttcaaaa ccttttatta tttcattagt atgtaaaaaa tagagtgatt
     5161 tatctttttt actattaaga ttcgagattg ttctcaacgg acgattaact aaatcaatac
     5221 ccctattagt aatgtttatt ttgtaatcat taacatacat agtttgacta gaaagtgagc
     5281 ttattcccga tatcacagca ccctttacgg tattaaatgg taaaatgtat gtggaatata
     5341 cagatttcgc caaatcataa tctatatatt ctgctatttc acgatctata gacgttgcaa
     5401 ttgtttcaca gtcaatagca atgatactcc cattagctat aatgatgttt tcataatgta
     5461 aatctgtaac ccccattaaa taagctataa aaataaatgc ccccagttga tagtaatgat
     5521 cattatgttc ctcttcaaaa atgccttcag gttcaatgga ttcttgaaaa taataattgc
     5581 ttcccttaac ttctcttaaa tcatttattc tattaataat ccccatgttt ttcagaaatt
     5641 tgtgctgaaa ctgaatgaaa ttcttttcaa aagagcactc tctccatttt aaaaagagtg
     5701 ttttcccacc tatactaact ctggatgtac tttttcccgc cttatgaata tccccttcac
     5761 ctaagattac ggataattca ccaaattctt caatatcgaa tctgttcttt aactcttcat
     5821 agtgcacatc taccaagtgt atactttcct ttatattatg aattgattga tcgaagaaat
     5881 tataaattaa tctaaaaagt tcaggatacg tactaaaaac atcttcccta agtgtataat
     5941 cactaataaa agtatcttga aattctttat aaaaagtttg aaaatttgca tctatatttt
     6001 cttgattttg ttggtaaaga gtgtttaaat gaaaagtcat agttggcgtt actaacgaca
     6061 tacaagaact atataaagaa tttatgttac tcttaaatat tttcatttct ttatgcgaaa
     6121 gatcatgttt attagataca agatattcaa caatatttgt ccaaacaaat gagaatttat
     6181 gttttttact taaccacttt aatgaattat cttgtctatg tactacagca cttataagat
     6241 ttgtagaatc tattgtattc acgaattcaa ctccctatca tacatctgct tatataaatc
     6301 acttttgttt agtaattcag aatgagtccc aatatttgtt atttctcctt cttgcaatac
     6361 gataactttg tcagcttcaa taatagtact taaacgatga gctataatta tttgtgtcat
     6421 attagcttgt tgtaaaaatt gagatatgaa cgcttctgtt acattatcta cagcactagt
     6481 cgcttcatca agaataagta agtccggatt atcaataatt gccctagcca agactattct
     6541 ttgcttttgt ccaccagata aattacttcc catttctgaa ataacagtct catatttcat
     6601 cggcattttt tcaatatcat tacttatact agctctttcg gcagattcta ttaattggtt
     6661 ttcatttata tctctattca tcaaaatatt ttctttaata gacttattaa agatattagg
     6721 tgattgcggg acatatccta atagactttt caaagattct ctattaacat cctcaatatt
     6781 gataccattt atctttatag tccctttctc gggaataaat aatcctaata ataatcctgt
     6841 aatagttgat tttccagaac cagtttctcc aactatagca actttttctc ctttattaac
     6901 tgtaaatgtt aaatttttta taacacaatc tgtttgacct ggatatctaa atgatacgtt
     6961 attgaaagaa attgttttaa tttcatcaac tgtaattgtc ccctctttta taaaataatg
     7021 atcctcctgt tcttctaata tatctacaat cctttcaaga ttattttgaa gtgtaccata
     7081 cacattaaag ctactataca ctccgtttaa actagtaaaa taataatttg atatagaata
     7141 cacaagcatt actgtaccta atgaaagaat agattgttga tacaaagata atactaaaaa
     7201 gaacattaat aatggagcaa aataagaaac gaattttgtt atattaccat atatattatc
     7261 aataaaactt ttttctttat acttatttaa agctacatca tactgattta acagcaatga
     7321 ttttacatat tcttcttgtc cagtagattt caaataagat atagcaagga gtgtctcata
     7381 ttctttcccc tgtagtttag ttccctcaat aatttcttct ttatttttta ggataatcag
     7441 tttacgaatg aagtataaaa ataaccctaa tacaatacta ataataatta aagatacaca
     7501 aagtattggg tcgatataca gcataaaaat caaaacaaat actagcatac ccacatctaa
     7561 aatactttta attaatgttt cgataaaaaa atctctgttt gattttaata aactaagtct
     7621 aaataagata tcactagaac tcctagtaag ataaaattta taaggtacac ggaagagctt
     7681 attgattaca ctcgtataaa tacttttatc taacttagca gaaaatataa ttactaaatt
     7741 actttttaaa agatcaaaaa ctaaaaacat aatcattaaa cccaaaagtc ctattaccat
     7801 gttactattt aatatagaat tacttgaagc tgtagtacgg tcgatgaggt ttttcataaa
     7861 aatagaaaca agtaaaactg tggcagttga taaaatagaa catattaaaa gggatattag
     7921 atcccaatat ttccccttaa aataatcaat gtacatttta aacggatttt cttttaaatt
     7981 tatttttttt gttgcctccg tgggctctgc aagcaaaact atattactga aatgttcatt
     8041 aaattcctct aacgttaatt ttcctcttcc aaagttagga tctacaatgt aaaacatacc
     8101 atttttaatc ttttccaaaa caacataatg atttttattc caaaataaaa ttaaaggttt
     8161 gtctgcgatt tgaattaaac tagttgaatc tgcttcataa tacgaaacat tgtacccaaa
     8221 agaatctaaa acctcaccca gtttttttat atgaacacca tctcgaccaa cctctatcgt
     8281 cttggatagc gttttaactg gaataaattg cttataataa cccatcaaca tagaaacaca
     8341 gcataaacca cattctgatt cttgaacttg tccaacatat ggaacctttt ttctcaaact
     8401 ttctcctcct tcaacaacct attcataata catctacaca ccgagatatt atataatcat
     8461 ggatttatta ttaattattt ataactactt aaatacatcc tgtttttcaa agattagtag
     8521 aattcataca gatattctcg ctattatttt agtggaaaat gtatctttat taaccattga
     8581 cactaaaaaa cagcgagaat aaactgtttt tcgagatgtt ttccctatcc tatctcttat
     8641 tcacatggag taactgagta gttacagtta ctaattaaca ttaagcaatg acattgctgg
     8701 aatgtcctta ttgacatatc taagataact atatactttg cttccttttc ccatcataaa
     8761 tccatacaga ttattagatg tcaacaaacc attggtatta ctatttaact tttccattaa
     8821 aattgtttgt acttctatat agagggtatg agatatcaaa ccttctttat aagcttcttc
     8881 tataatttcc ataaaactac ctatcccatg acataagcaa taacccaatt tatcaagctc
     8941 taattcatta tttattatcg cgttgcataa acctgttaac tttttattta gatctttaag
     9001 atcaacacat tcacctattt ttataagttg aattttggat aataaaatcc ctggtaaacc
     9061 ataacaataa taattagtag taagtgcatt atctctagga tctaaataat tatttttttc
     9121 ttcgacatac aacaactcct ctttctcaat taattgattt actaatttat taatttctat
     9181 attctttaaa atgacattgg cagaagatag ccctaagata atcccgctat aaccatgagc
     9241 gaagcctgca ccaatagtga ctgaatttaa agcctttgat aaatatacat aataatcttc
     9301 aaggaataat ttggaagcat ctttaaactt gttagataag taaatggaat catccaataa
     9361 aaggttggca agaagtacac ttattccaga tagacctgtt atgtagtcta ttttatattc
     9421 cttagagaaa tctattttta gaagcttata gcaatcgtta acctcttcta taaagaatgt
     9481 ttctgatgta tttttaaaca aaagataatt tatatatata tatgaaccaa taccagtaaa
     9541 cgcgtctagt aattctggga aatgcaattt actagatttt atagaagata ttatcttttt
     9601 aaagtaatct actgataatt ccaactcatc cctaaaatgc gacataagta aaattgttcc
     9661 cccatattca tataaagaag aatttatact cgataatttg catttatcac ctgcatgaga
     9721 aggtaataga cttacaaagt aaccacctct atctacaatc aactctgaga attctttcaa
     9781 atctgatatc acttgcgctt ccccatacat ctccttactt gattggcttt gagatagtac
     9841 tggatcatca cttttattat tatatgcaga aataaataaa ctggattcaa tatgataaat
     9901 ttgcctattc atttcttgtt ctgaatattc ttcaattcta ttcattatca tgtctttaga
     9961 tgagctcaaa aaataatctt cacagactat ttctccttta tggttatata aatgtcgatc
    10021 attaaaataa gcataaaata tagggatatc accatttaac aaggtaccta cttcttcttc
    10081 tgcaactgct ttctgcttat cgtcattttc attgttactt agcagaatgt taaataattc
    10141 tgccctatag gtatcctttt gcatatagta tgcttcatat gatgtagtta aaaactttgc
    10201 gtaaacatgt gtcggtcgta acacttggcg tacaaaattc ccttcaatga cttctagaaa
    10261 tgcatttgta aagtattttt tatttttcca cattttctct gacattgatt taaatccatc
    10321 ttttatacat tccaaataat ctataggatg gacaatctta tccttactat aaatcctatt
    10381 cagtttgtct tctattacaa ttggagcctc ttcgtaccta acagaatcac tattataatc
    10441 aacaattact ttctgtgtat aatgaaaatc gttatacaca gctgccccac cagttaaagc
    10501 ggatatattc aaatcacttt ccctcatata tgtaggataa atcatcgtat caagtactga
    10561 atcagtagta taatccaaga aggcaagcac tggattgtct tccttgaatc gtttaacccc
    10621 aaccagtgtc tctaagtcta caaaaaatgg aactcgattt gagacaatta cgttttcata
    10681 atgcatatcc gtagatttaa atgcatacat aatcgctgaa attacaccaa tattataata
    10741 atacttttca atatcttcta tactttcagg agatttatat acaattaact catgaattga
    10801 aaaggtatca tatgaataaa tagtaaagtc gtactctctt atttgagact gaattagctt
    10861 cataaaacgt tgatctaact cagccattcg gggtttataa atatagcgag tatcatctag
    10921 attaataata cagaccgact taccttctgc atgactatca ccagcatcta aagagatact
    10981 tttcaaatat gtaaaataaa aatcgttttt aaatgtttct aaatctaata aaattttatt
    11041 tatgtatttc tcaaaatata taacacgctt attaagcata tgctctaatt ctttaaatcg
    11101 agagaaaaaa tcaccaataa attcctcgct aatcaattcg tagtatgtat ttatactact
    11161 ctcctctggg ctaataccct tttctttcca taattgaaaa tcaattaaaa aactatcttc
    11221 tactaatgga tataggttat tgattattgt gtcttctaat tctttttcaa cctccaattt
    11281 attataagtg gtattaacca atttgatttc cttaccttct aaataggtag ttataaactt
    11341 aactactaaa tcataaaagt ttttctccat aactctctcc ttaaaaatca tcctattttt
    11401 agataaaaat ggattttttt gataaatttc aatttcatta tagcataatt tatccatata
    11461 ttatatgata tttacatata aggtttatgt tagggggtta atggaaaaat gttcaaactt
    11521 aaaaaagaaa gtatttctga attagcaaaa gaaagttact tgaaccaact ggataagaac
    11581 aataaacgtc ttgaaaattc tttcggtgcg gactgcaatt tttggaatat atcatgccat
    11641 cttggaaatg acggtagtgt gtgtactcta acaaaagaat gccgcccagc gtgctggtaa
    11701 taatcataaa aaaaggagtg tcataaagtg aaagaactta aaaaaaatat tgaatctgaa
    11761 aaagtattaa aaaaattaac cgaggtacct gacttaacag gtggaacatc aacaactgtt
    11821 ccttgtggaa ttggaagtac tattacaatt agcattgcat attgtccaac atctaaatgt
    11881 actgaaagat gtggaacacg cggttaatca attaatcaac atagacctta tataaaacta
    11941 tcattttaaa atctttataa ttatataaaa taatttaaca gtaacataaa tatatataat
    12001 ttattatgat aaaagtttcc ctctataact ttctctttgt ctatcatcct attccaaggt
    12061 aaaaatggat tttttttgat aaaattcaat tttattgtag catatttttt ccagatagta
    12121 tattatattt acatatcagg tttatgttgg aaagaaagag gagaaaaaat gttcaaactt
    12181 aaaaaagaaa atatttctga attagcaaaa gaaagctact taaaccaact agataagaac
    12241 aatacgcgtc ttgaaaattc tttcggtgcg gactgttctt ggtggaatgt atcatgccac
    12301 cttggaaatg acggtaagta ttgtactgcg tcaaaagaat gtatgccaac gtgtaacgat
    12361 taattataaa aaaggagtgt aataaaatga aagaacttaa aaaaaatatc gaatctgaaa
    12421 aagtattaaa aaaattaact gagtcacctg acttatctgg cggaacaact atcccttgtg
    12481 gtgaactagc agttgtaatt actgctgcat tttgtccaac atctaaatgt actactagat
    12541 gtggatcacg cggttaatca actaatcaac taatcaacta atcaacatag accttatata
    12601 aaacacatat tttgtaatcg ttataattat ataaaataat ctatagttat tataaaatat
    12661 atatagttta tcattataaa caaattccgc tgaacagatg ttttgcggaa tttgtttgta
    12721 attttttaat ttaatggaaa actatattct gaatttccat ctaaatgttc cttttatagg
    12781 ccccttgatt ttatttcaaa cttatataaa aggcttgaaa ccccataaaa accctattca
    12841 gatgaggtga taacgtgtgt aactatatca taaagacagt taatttaact aaagaattta
    12901 aatcaaaacc agttataaaa aacttaaact tcactttaaa aaaaggagaa atttgtgcca
    12961 ttataggtaa aaacggcgct ggaaaatcta ctttttttaa aatgttatca aatcaagtat
    13021 taccaacaga aggactgatt caacttgata atcaggaaga taaggatctt gatttatcta
    13081 gaaaaaaatt cagttttcta atagaagctc cagccttttt tgataacttt acagctaagc
    13141 aaaatcttga atactacaga attcaaagag gcatagataa taaaaagctc atcgacgaat
    13201 taattagaat ggtaaagctt gaagaacata ctaaagtaac attcagtaac tattctatgg
    13261 gaatgaaaca aagattggga attgcacttt gcttactgtc aaatcctgat tgcctagtat
    13321 tagacgagcc aacgaatgga ttagatgcgg aaggtatccg agaactacga caattactaa
    13381 taaatttaaa taaagaaaaa aatactacaa tcttaatttc aagtcacgta ctatcagaat
    13441 tacaaaatat tgctactagg tatgtttttt tggataaagg aaaaattatt gaagatataa
    13501 acgctaatga ttttgaaaag aaaagttcac agcacttgaa aataaaagta aatgatactt
    13561 cgttggccat tgatttatta aaacagttcg aaagaaattt acagtgtgac atccttgaag
    13621 acaattggat catcgttaaa aataatataa ctgatggatc aaatatcaat gcattcttaa
    13681 ccaaaaacaa tatcattgta tatgaattta aagtcgaaca tcataattta gagggctatt
    13741 tctttaatct tttaggggga gacttgacat gataaattac ataaagagtg aattttatcg
    13801 tttccaaaga agtaagttat tttttgcaac cactggtatt tccttatctc tagtaatact
    13861 tgcttctatt gcactctttt atagcttaaa agcagatgaa actttcaaat acgcaaattt
    13921 agaattctat tttgctaata taattagttt ttatatagta attatcttct tagcttatgc
    13981 gatttcttca atacttgctg ggaaagacct aactatcata cgacaatcaa ttagctttgg
    14041 tatttcaaga aaaactattt tctttggaaa gttaatagtt tctctttctt actttctaat
    14101 tttagggata actctcgtta taagttcgat gatcataggt aatttacttt tagaacacca
    14161 tataaattct attttttccg actatcttct tgctttaact aacatgcttc ctttgattgt
    14221 aagttctttt atcttagcat acattataca tatattagca ataaaagaca ttgctaatat
    14281 agcaatcctg atacttatat atagcatttc tggagatatt ataaaattca tctccaaaag
    14341 cttaccattt atcagtgact catataagta tttcccatca agtatattaa gcactaactt
    14401 tactaatttt gcttcacata aaggcgtttt cctaatcgaa gcatgggttg ttggcatatt
    14461 gttatcaatc atttatttaa ttataggtgt attcttattt tcaaaaaaag atctataact
    14521 gcatatctct gaaatacact attactttta ggtgacaaaa ataagatata atatactatt
    14581 tttgtcatct ttttatcatt gcactataca ggtaatagca ttttcctata actcttatat
    14641 aagcctcacc ccatttttaa tatagttgta ctcttttatt tttcttcttt ccaattttat
    14701 agatcagatg accacttata aaccaaacac aattaataaa tgttaggtga actgaaacac
    14761 caagttctct caaaacttca gggatatcaa gatatattta aaaatgatac tagtagccaa
    14821 ggctatcaaa ggaatatctt gtttaaatgt tttctttaag tatcccattt atgatctccc
    14881 ttatagtatt tattaatttt caataaactt ctcataacat tctgttttcc acatttctcc
    14941 atttcttgca ccaaagtctt atagtaatag catatctccc atctcttttt ccacaattaa
    15001 agccgttgca ataactgcct caattttcta ttttattttc ataaaaacga aaagaaacgt
    15061 ttacatttat atctatatat gttaatttat agtagtctat aagaatagta ataataggag
    15121 atgttgtaat tgaatgataa actgaagaaa ttaattatat cagggaccct agctggaacc
    15181 gtatttaata ttacaaatgt agtttctgca gattccacag atatatctgg aaaagcaaca
    15241 tatacaaatg cgatgagtag tgattatatt caggggaatt taactttttc tactgctaat
    15301 ggagagatta taaaaatcgg ccctctacaa tccattaatc ctaaaaacaa tagtttttat
    15361 tttttttcaa ataagaaaga ttcattacct attttcaaaa aggtagaaaa tggggttgaa
    15421 caatctataa aaatcgatcc tacaaaaact aatggaaaat ataaagttcc atttgatttc
    15481 ggaaacggtg aatcgataaa ggtagaagaa gatggttctg cagttattta caataaaaat
    15541 aaagaatcaa ttgccgtagt tatgcccact gaggctaaat ctcaatctgg agaaaattta
    15601 gaagtaaata ctacacttaa aaatgagaac accttagagt attatgtaaa tattaaagaa
    15661 gaagttaatc ccgtaacaat taagaacaca accacatcat atgctttctc acaatatttt
    15721 tctagcggta actggattgt aagggatggt atggtttctt taagcttaga acccacaagt
    15781 gcattaacaa aattaattgt gaaccgtgca attcgaacag acagttggaa taaagttaag
    15841 gatactttct cgatggatga tcaatggagt aatacaagct ctatgcaaaa tcaatattta
    15901 tgtcactatg attttgccaa atcatttaag acaccatgga acttagaacc acatcgtcca
    15961 gatgtcggct atttgaagac tgttgctgct acatgcaatc cgtaataaac ccataactat
    16021 ctagaagatt aactatctag taatcctttt tcttcttttc aacaaagtgc gcatttcgtg
    16081 ctttaagcag aacttcatag aggaagagcc gatttcctgc acactaaagg ataatcggct
    16141 ttctaagtca aaaatattat tttacaaatc gttctttgta tatcttcttg atctgcggct
    16201 tcagtaagtt cctcgtaccc tgcaaacacc tcagggaact gatataaaga gatctcaata
    16261 attgtgtcat ctgtagttct aacataaaag tacttaactt tatccatgta atcgttataa
    16321 aggtaatgac tcttaatctc gtgatggtag tgttagcttc caagacttca tacagtttgc
    16381 ttctcgtttc atcgatatta gaatattgat caacaccctt tgatctcttt cctcttccga
    16441 gtaaaatagc gtctttgttc agttctatcg cgccaatgcg tatagacaac tccttattat
    16501 gatattaaat ttttttattt gattctcata tagagtcaca tgcgactttt tccctgttta
    16561 tggggctctt acgtagtagt aagaaccatt tttttattaa gttattcata taaatcttaa
    16621 tatacagttg taaagatagt tacttaagtg ttaaaattcc acatatactc cttagggagt
    16681 tctcatataa ttaaacaaga gttttaaaat tctcgaatct tagccccttg gagcgccctc
    16741 caaggggctg caacaattaa aatatcgttt ttgttcactt ttttgataca tttatgaaac
    16801 attcatgtgt tatcttcaat acgttctttt ctttttataa tatcatgtga gatataccaa
    16861 cacagaaagc cctagccccc taatcctagg gcttcttttt taaataagga atttatgaac
    16921 tttattattt ccaccctttt tcgaaattta atatacataa tatataaata tttatgtcat
    16981 agtacttttg tgaaacatca cgtgtttcaa atacaacatt ttttgataac ctcttatctt
    17041 tccgtaagag gtcttttttt tataactact ttatttaaat ttaccttaat taacgccaag
    17101 ttttcttaaa attcaaatta ataaatgtat aatataatta aactatttgt atgaggggtg
    17161 atttttatga aatggaacca aaagtacaac ccaaaatatc tcttttaccg catgtatagt
    17221 tatatttata aagatcttga tgatatatca tggtccttaa aataatttag attgttatga
    17281 gtacacattt gctgtgtgct cttttcacat tgctataaaa taacgctttt gtttaattta
    17341 ttttataaaa attcattttc ataagaactt cccttatatg ctatactcat tcataaataa
    17401 ttgtataagg aatgttaaaa atggatgata gatcgtcaag acaatggaaa atgcgacaaa
    17461 agttaagaga actgaaaata aaaaacagaa ttgatacaaa ccctttgttt aatgaatgcc
    17521 ttgaatccct aggaaacgaa actctcattt cctctcggga aaaaagccag cagattgcta
    17581 ctactttaat gaatttattt cctataactt tctcaggaag aatagattgg aaacagatag
    17641 acaatcaatt aatagcttcg cacaaagaac aactaatttc ccttattaga gcacaccaac
    17701 taaattttga tggacagatt tttataatat gggataacta tgaaatccct gtagtaagta
    17761 caaatcttga tacagtattc caatcactag ttgacgttga tgcggtcagt ttttattact
    17821 ggctattaga taaagaatat aaattcgtaa ttgaaataat tgatgaagaa ttgattaagg
    17881 ttgagtttcg ctaatactct aggtatattt cctcatcctg cggttctaca aaattcaaat
    17941 ttcattttaa tcaaatactt caatcacatg taaaagttac gtaaagattg ctatgattca
    18001 atccttccac cctagaaacg ttatataatt aaatcacaaa caatcaggtt tgtacctttc
    18061 tgtacgacat aactctttgc taggagcaaa tcctagcctt ttttatttaa tcaccctact
    18121 tctcctctaa aaccactatc cacagttcca attaccacgc ttaacttttt attacgcgtc
    18181 ataacgctat acttcctaat ccaaatacat tatctcttct aaggttctat ccgaaatata
    18241 agtagtaata atttctatct ttctttaatt ctctttaggc attcctgtag cttcgctctc
    18301 ggacttcgcc tcaaaccgac gaatcttcca cttttcacct tcattttgaa actctattag
    18361 agaacgtcat aacgctatta cgcttcgaaa atttgctcac ggtatttgtt tcaatataat
    18421 caccccaccc cccccgatta caccctccag ttttagttga ttcatgcttc tcccccatac
    18481 ccatcaactt aagattttga aatacaccca aaacgaaaat tttttctctc tagttatatt
    18541 tctgagaatt aagttcattt tttcgttttg gagaacaatt aattttttag ggtgatggat
    18601 atatatattg ccccctacat agctaaaaag acatataaaa tacactctct tctccaacaa
    18661 ctctttcttg taaatttaag aactataact tcactacaaa taaaaagcag caactataca
    18721 gttgctgctt gctcaatttc tttttttatt tcgacacttt taatttgatg ggcatattta
    18781 gaaagaatct taaattcata ttcttcactt tttattgtct gtccttcttc gatatcataa
    18841 ttctgcatca taatccaacc accaatcgtg tcaacatcct catcattcat atgtaatccc
    18901 agcaaatcgt ttaattcact aatgagtacc ttaccttcta ctatgaaatg atattcattc
    18961 atttgctgaa tgggcggacg ttcatcttcg tcatattcgt cacggatttc tcctacaatt
    19021 tcttctagaa tatcctcaat ggttacaata ccagctgtac cgccatattc atcatgcaat
    19081 acagccaatg gaatacgttt cttttgcatt tgcagtaaaa gatcatgtat tggaatgctt
    19141 tcaatcgctt ctattactgg acgtgtatac aagtggatcg aatcggattc tttagtttct
    19201 ttatttatgt aacgaataaa gaagtctttc acattcacca tcccaatgat ttcatctttg
    19261 tcttctccaa atacaggata acgtgtgtac ttttcatggc gaattatttt tatatgatct
    19321 gctaaagaat tatctacatg tagtcctata atttccgttc gagggaccat aatttcttta
    19381 gcaatacgat tatcaaattc aaaaatatta tttacatatt tatactcagc ttgattaatt
    19441 tctccacgct catagctttc agagagaatg agccgtaatt cttcttctgt atgagccacg
    19501 tcatgctctg atgctggttt taggccgaat agccctgtta tcatccttgc agagccattt
    19561 aacaatcgta taaatgggta catgatttta tagaaccaaa taagcggagg cgaaagtaat
    19621 aaagtaatct tttcagcctt ttgaatcgca aatgtttttg gtgctaattc tcctactacg
    19681 acatgtaagt acgtcatgat agtaaaggca attcctaaag ataataaact tgccatggaa
    19741 ggattgatat tcactttatc aaataagggg tgtaaaagtc tttcgatggt tggctcacct
    19801 agtgcaccta gtcccatcgc tgtcactgta atccccaatt gacaagctga caaatattca
    19861 tccaggtttg tggtcacctt tttagctgca agcgcacctt tctttccttc taatacaaat
    19921 tggtcaatct ttgatcctct tatttttact atggcaaatt ctatcgcgac gaaaaatgct
    19981 gtaaaagcga ttaaaactac taccatgatt aaacttaata tgttcaacta atccccttag
    20041 cttctttgaa actaaaggac cacctcctga taaatttttc tcattcccta aatactgctg
    20101 tatacaactt aaaatattat tttatataac ttaaattctc ataattatta ggggtactct
    20161 gagaaaattg aggtagttca gccaactatc cgagtcaaca tctgattcca ataattttcc
    20221 accgccttga ttaaattatc tacatgctac catgtaacat aaatcaccgt caaacatcac
    20281 aatttttttt gaaaatcaaa ttataagaaa cctctgtaat tcaaaatttt catatcaaag
    20341 atatacataa aaaactccat atttacattc tgaaagtatt ataaaagttt aacctttata
    20401 tagcaggtac cgattattaa agaaataatg taataagatt aatattatag ttcatcttct
    20461 tccgcttttt tactattata tttaccaaat ccatacatac ataaaccgaa aagtcctccc
    20521 catataatgt tgccagtaag gtctctcata gtaataggtt ctccagataa atgcggtaac
    20581 aaagtatata aaacataaaa cataaagcct gaaattatcg aatttcgtat taatgtttta
    20641 ttacttgtat aacgtaagta cacttttttt atgcgcatca ttataaatat ataacatgat
    20701 gttattaaaa ggataattaa ggatagcgta ccaagtgatg tcacttcttt atttaaaatt
    20761 acatcatata ttatagctcc aaaacagata atgctagata atattccagc gttcgccatt
    20821 atttcaaatg ctgtattttg ttctcgctca tcaacagaag taccttttcc gaaaagatat
    20881 aattttaata acttagtcat taatcttcct cccaaaataa atcatttaat gtaacaccta
    20941 gacttttgca aatttcaata cataatttca aagatggatt gtattcgcct ttttctatta
    21001 gaccgattgt ctgtctactt acatttgtta attttgctaa ttccccctgt gtcataccct
    21061 tttcaagtcg aattcgcttt actttggtaa gcatattaga agcctccaat acatttattt
    21121 cctttgtaat atatatgtta cattagtaat gtatatacgt caatagttag aatttttaac
    21181 atcctatatt tccaaggata tccttctata caaatcaact ttataaattt gtatctataa
    21241 aatgaaaaaa acactattct ttttgtagaa atatacagaa aggatgaagt tttttatgaa
    21301 tatttcgatt caagatgaat tacaactatt tgctgaagaa ttacaccaat atctttctcc
    21361 ttcattttta
//
