LOCUS       NZ_NTSF01000005        21423 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS021634
            AFS021634_110_H4_Contig5_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTSF01000005
VERSION     NZ_NTSF01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 67953)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 67953)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.88x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563165.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 02:22:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,903
            CDSs (total)                      :: 5,824
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 84 of 212
            Pseudo Genes (incomplete)         :: 133 of 212
            Pseudo Genes (internal stop)      :: 67 of 212
            Pseudo Genes (multiple problems)  :: 60 of 212
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:49:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23422
            Orig. end                         :: 44845
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTSF01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21423
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21423
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21423
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11423](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11423)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    complement(1115..1128)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            complement(1226..1717)
                     /locus_tag="CN325_RS04720"
                     /old_locus_tag="CN325_04720"
     CDS             complement(1226..1717)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113634.1"
                     /locus_tag="CN325_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04720"
                     /product="hypothetical protein"
                     /protein_id="WP_000113634.1"
                     /transl_table=11
                     /translation="MARPMKLNDELINRLTQYIKVGNYIETACALVGISRSIVYVWLKQ
                     GRRAIETSEKTGEVVPRKDKIYVKLVMEIDQALAFSEARDVETIGEHAKSNWKAAAWRL
                     ERKFPTKWGRKDQLQANVNHSGEMKVEHNKMAMKIGCDEEMLDLAMKLFEKVQGGELQS
                     "
     gene            complement(1735..1920)
                     /locus_tag="CN325_RS04725"
                     /old_locus_tag="CN325_04725"
     CDS             complement(1735..1920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892958.1"
                     /locus_tag="CN325_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04725"
                     /product="hypothetical protein"
                     /protein_id="WP_000892959.1"
                     /transl_table=11
                     /translation="MLEQDIDTMPICSICLEKCLWVLKFPITIQYCEQMLIREVVDDNI
                     TTICIECLEKEIQMMS"
     misc_feature    complement(2109..2124)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.72"
                     /tool="antismash"
     gene            complement(2154..2654)
                     /locus_tag="CN325_RS04730"
                     /old_locus_tag="CN325_04730"
     CDS             complement(2154..2654)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205173.1"
                     /locus_tag="CN325_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04730"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_098390261.1"
                     /transl_table=11
                     /translation="MRDLIIQYKETLCKLESAKISAKEEENKILTSMISDVTYALEWMK
                     NAKMPGNRRGIERRAAYQREKSYDSLLMQRYFRSTDTTYEWDDENKESVISEWERIKLE
                     DALSTLTKYEREIYIMSRGRGITQEKIAKYLNVSRSTIKTILYRSEIKIAKQVRKSLFC
                     ESS"
     gene            complement(2936..3307)
                     /locus_tag="CN325_RS04735"
                     /old_locus_tag="CN325_04735"
     CDS             complement(2936..3307)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000931950.1"
                     /locus_tag="CN325_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04735"
                     /product="ArpU family transcriptional regulator"
                     /protein_id="WP_098390262.1"
                     /transl_table=11
                     /translation="MLNIELPVLNKEATKENVLKAIKKYRLFMKCNYLNETILSKENIF
                     KENAKEERVNYIIAMNKGLEKLDIESDRIIIQKYLLKNRVNRYEVMKELNLSEGDYYRK
                     RNTAFYNYAYALGIEVEEC"
     gene            complement(3385..3561)
                     /locus_tag="CN325_RS04740"
                     /old_locus_tag="CN325_04740"
     CDS             complement(3385..3561)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765291.1"
                     /locus_tag="CN325_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04740"
                     /product="Fur-regulated basic protein FbpA"
                     /protein_id="WP_000765291.1"
                     /transl_table=11
                     /translation="MKLFLINQLIENGIYKYKDKQLYELNSDELIKLIKNHKDKKINVS
                     NTMYEIIHEGYKP"
     gene            complement(3566..4180)
                     /locus_tag="CN325_RS04745"
                     /old_locus_tag="CN325_04745"
     CDS             complement(3566..4180)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002169548.1"
                     /locus_tag="CN325_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04745"
                     /product="hypothetical protein"
                     /protein_id="WP_097814460.1"
                     /transl_table=11
                     /translation="MRTYKGFEAIKRMKTNWITTVQETPMCWKIEGERVIADYLGKKES
                     YQQINFFFENEFIDCRETIRKGELLYIENEKSEKFIAEYCKENEKEIKHGSWFWINGEE
                     FSNNYGHFEKSTKLKIRKAEKSEKLLFEQAKLFAIKGRKINEFRLGDVVERDNKLYKVA
                     IVKSGSESQIVVGCVPINGGAICYYNSKDIEIQFFVEDMVV"
     gene            complement(4370..5152)
                     /locus_tag="CN325_RS04750"
                     /old_locus_tag="CN325_04750"
     CDS             complement(4370..5152)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003163318.1"
                     /locus_tag="CN325_RS04750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04750"
                     /product="ATP-binding protein"
                     /protein_id="WP_170925764.1"
                     /transl_table=11
                     /translation="MKFLSETCVICNQERKRMVRLMEIQGETICPVCRLEEENRRLEKE
                     MNVFRYEKEERKRKSIFYDQSLIKDETIKLARFSTFISECEEDEKNLILAKKALTDYLN
                     DIRFNLILVGKVGAGKSHIAYSIAHEMNEQSSDKVMYVTSSELFDYIRSTFNTQSCETE
                     HSITNMLISMDLLVIDDLGAELGDMDINDLKATAFVNRVLFKLFDGRQGKKTIVTTNLT
                     GEAIIKAYDERVTSRMFNTYRHIEFKKTRDKRKRKLPF"
     gene            complement(5136..5900)
                     /locus_tag="CN325_RS04755"
                     /old_locus_tag="CN325_04755"
     CDS             complement(5136..5900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067428.1"
                     /locus_tag="CN325_RS04755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04755"
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="WP_000096618.1"
                     /transl_table=11
                     /translation="MSSLLIQDEPLLVLPRLASKIGLNEAIFLQQIHYWLKRSKHYYDD
                     RYWVYNSITNWHKQFPFWNERTLKRIVKNLEEFNLLISGNYNKLKFDKTKWYSINYDRL
                     VELEIDNDCDKLSQRKEHIVMMENDNMSQPIPETTQKINSENTTQKDIVEIINYLNSVC
                     NTSYRISTKKTQMLIKSRLQEGFNINEFKEVIETKAKEWLYTEQAKYLRPETLFGTKFE
                     GYLQQRKMVKSNGFNKGNRYSTKSFEENEIPF"
     gene            complement(5978..6262)
                     /locus_tag="CN325_RS04760"
                     /old_locus_tag="CN325_04760"
     CDS             complement(5978..6262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513556.1"
                     /locus_tag="CN325_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04760"
                     /product="hypothetical protein"
                     /protein_id="WP_098390263.1"
                     /transl_table=11
                     /translation="MVFRVTKKQGYVSNSTNENEEFRNTSCFESEKLSYKQLKMIYAKM
                     HIIALKYDGVISKEEIKNKLKVKLKIQSLSDLTRKQANQAIKVLIGWEI"
     gene            complement(6329..6595)
                     /locus_tag="CN325_RS31310"
                     /pseudo=""
     CDS             complement(6329..6595)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012095424.1"
                     /locus_tag="CN325_RS31310"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="group-specific protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLNIQVNERAIRRLYLEKLEEKLKEVDAEFVFWDTREFLKRTCMS
                     WSTV"
     misc_feature    complement(6736..6745)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(6780..6986)
                     /locus_tag="CN325_RS04765"
                     /old_locus_tag="CN325_04765"
     CDS             complement(6780..6986)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513557.1"
                     /locus_tag="CN325_RS04765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04765"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000549412.1"
                     /transl_table=11
                     /translation="MHKMIFLERKLKRKTIEEVADFLNVSPRTYWAKEHNKSEFTLKEA
                     HMLSCYLEKSIEELFPDLFLNNL"
     misc_feature    complement(7024..7039)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.73"
                     /tool="antismash"
     misc_feature    complement(7024..7039)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.6"
                     /tool="antismash"
     gene            7124..7768
                     /locus_tag="CN325_RS04770"
                     /old_locus_tag="CN325_04770"
     CDS             7124..7768
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834513.1"
                     /locus_tag="CN325_RS04770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04770"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_071731715.1"
                     /transl_table=11
                     /translation="MKSFGLKLSQLMKKNNMTDEQLAELLSVSRTTVLRWRNGERSPKM
                     SKISQIAKILNVSATYFIDENESYCPEDHVITKRNIPIYGTIAAGKPIEAIENVIGDIQ
                     VPDIILDKYGFEKLLALRINGDSMNRIVHDGHIAVLERTTNINNGDIAAVLINGYDATL
                     KRIYKTNNRIILEPDSFNPSIHPLMFDCTDIENCPEIKVVGKYIWSCAPIQ"
     gene            complement(8655..10004)
                     /locus_tag="CN325_RS04780"
                     /old_locus_tag="CN325_04780"
     CDS             complement(8655..10004)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212114.1"
                     /locus_tag="CN325_RS04780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04780"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_098390264.1"
                     /transl_table=11
                     /translation="MRFNYLNSIKEINHIAVPLVVNSIAGLLIKLVDQAMIGRISVEAY
                     GAIGVVSSLLFTFAGILGVMSVSFNIYGSRSMGQEDIKSFNNYFISSIFLNIIIGISLA
                     LLLLIFQRPLLSIVFGFEGNILKDSIQYLTIMSVYILIQLLLFTFSTFFKIIKETKWIF
                     IGSTVASILNVILNYLLIFGNFGFPKLGISGSAIATIIALSINLIIYMYLCRKHLKITF
                     QNIKIYINNLKFLCKKSTSLVGQEILEGGIFIIGVNAMIARTGDIQLSGYLLVSQILSI
                     ILIPMYMYSSAILTLVSERYGSKQLIDLKELPKVTLGLIMVFYMFLSIIFVFLKYEVVA
                     FITNDTNLINYAASILTFIIIANIFNPLHNVYKYALQAIGQSNYVLIKTAIINLITFVM
                     MIITIYVFNLNIFGVFISLFFNYVMLSIIFSRKYKGILNGIESNKKKILA"
     gene            complement(10001..10315)
                     /locus_tag="CN325_RS04785"
                     /old_locus_tag="CN325_04785"
     CDS             complement(10001..10315)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Streptide_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357890.1"
                     /locus_tag="CN325_RS04785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04785"
                     /product="hypothetical protein"
                     /protein_id="WP_080495054.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-08,
                     bitscore: 27.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 4.6e-11, bitscore:
                     35.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDIKCFIIHGKKNIIFRQEGDKYVFFDPIALEYYVTNFIGAEIL
                     YYISKGKDFQFIADKISEEYEINEDMSKETIREFLLDFPLLSIISSNLIESDIYKELSA
                     "
     aSDomain        complement(10022..10228)
                     /aSDomain="Streptide_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM enzyme in a
                     streptide-like cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CN325_RS04785_Streptide_RRE.1"
                     /evalue="1.80E-11"
                     /identifier="RREFam022.1"
                     /label="CN325_RS04785"
                     /locus_tag="CN325_RS04785"
                     /protein_end="98"
                     /protein_start="29"
                     /score="35.3"
                     /tool="antismash"
                     /translation="IALEYYVTNFIGAEILYYISKGKDFQFIADKISEEYEINEDMSKE
                     TIREFLLDFPLLSIISSNLIESDI"
     aSDomain        complement(10073..10285)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CN325_RS04785_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.10E-09"
                     /identifier="RREFam002.1"
                     /label="CN325_RS04785"
                     /locus_tag="CN325_RS04785"
                     /protein_end="81"
                     /protein_start="10"
                     /score="27.3"
                     /tool="antismash"
                     /translation="GKKNIIFRQEGDKYVFFDPIALEYYVTNFIGAEILYYISKGKDFQ
                     FIADKISEEYEINEDMSKETIREFLL"
     gene            complement(10308..11423)
                     /locus_tag="CN325_RS04790"
                     /old_locus_tag="CN325_04790"
     CDS             complement(10308..11423)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247066.1"
                     /locus_tag="CN325_RS04790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04790"
                     /product="radical SAM protein"
                     /protein_id="WP_069604343.1"
                     /sec_met_domain="PF04055 (E-value: 6.1e-25, bitscore: 80.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 9.1e-56, bitscore:
                     181.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.3e-14, bitscore: 44.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 4.2e-08, bitscore: 25.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.5e-16, bitscore:
                     50.4, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.5e-11, bitscore: 36.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNYYSAPSLVDISITNRCNLKCDYCYASSSPFETKNEEMDLNHL
                     NNLFQDLDDMNVHRISLTGGEPFIRDDFFEILSATQKYKFAKIINSNGILISDKIASKL
                     SKFDFDRICITLDGSCPEVHDIIRGHGSFKKTIKGIKNLQKYNLPVSTLFTLNKTNVND
                     LINTIKLNELLGITYMTVMVVCPTGRASDGSILADKNNWYPMFLNLSEMKSRGDIKLNF
                     KIIPPNESPVFWLYYFPLEHYNRLDLLSVWDQDLNLTDIHTKEREISCQAGVKACSIAY
                     NGDVFGCDLMMGIDQFRAGNIKSTSIKEIWNESSVFNKLRNISFDNINGKCGSCSHKWC
                     GGGCRSSAFNLTNSIYGSDNSCFFEESVANG"
     gene            complement(12557..>12790)
                     /locus_tag="CN325_RS04795"
                     /old_locus_tag="CN325_04795"
                     /pseudo=""
     CDS             complement(12557..>12790)
                     /GO_process="GO:0030638 - polyketide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764204.1"
                     /locus_tag="CN325_RS04795"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04795"
                     /product="ester cyclase"
                     /pseudo=""
                     /sec_met_domain="PF07366 (E-value: 1e-12, bitscore: 40.2,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFFKEGFVKSPNSSAEIKRVVAEGDTVALHVHFRANSQDKGVAI
                     GDLFRIKDGKIVEHWYVIQEIPSKTTNNNTMF"
     gene            complement(13005..13298)
                     /locus_tag="CN325_RS04800"
                     /old_locus_tag="CN325_04800"
     CDS             complement(13005..13298)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631350.1"
                     /locus_tag="CN325_RS04800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04800"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_098390266.1"
                     /transl_table=11
                     /translation="MITLISERNLAEIHEDDVDVLKVMAHPVRLQIVNELMQHKVCNVT
                     QLTEILRLPQSTVSQHLSKLRGTVLRSERRGIEMHYFIDNAKARQIVEILGL"
     gene            14145..14549
                     /locus_tag="CN325_RS04805"
                     /old_locus_tag="CN325_04805"
     CDS             14145..14549
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495046.1"
                     /locus_tag="CN325_RS04805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04805"
                     /product="DUF3221 domain-containing protein"
                     /protein_id="WP_098284862.1"
                     /transl_table=11
                     /translation="MFNKKQIFVTTVTTLTLGCGFTFGLTPAFADSNKISANNIPVHSI
                     QNQEQEPFTGYVISVENNYLVVAATSTKDEALAYQHDWWDLVSQNKILRVPVSDGANYT
                     LGEKLNVYAAAWTKSLPPIAVMPTIEKVFQ"
     gene            complement(14821..14955)
                     /locus_tag="CN325_RS31315"
     CDS             complement(14821..14955)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN325_RS31315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255289904.1"
                     /transl_table=11
                     /translation="MIDYYQIFLITMTGIALFFYIQHAGKPTKRNKWIFFVEYFYFSF"
     misc_feature    15348..15363
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     misc_feature    complement(15348..15366)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 28.05"
                     /tool="antismash"
     misc_feature    15350..15364
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: strong, score: 24.73"
                     /tool="antismash"
     misc_feature    complement(15351..15366)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.65"
                     /tool="antismash"
     gene            15446..15865
                     /locus_tag="CN325_RS04810"
                     /old_locus_tag="CN325_04810"
     CDS             15446..15865
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755788.1"
                     /locus_tag="CN325_RS04810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04810"
                     /product="hypothetical protein"
                     /protein_id="WP_029443236.1"
                     /transl_table=11
                     /translation="MKKAILAGALGIAVLSGMNLPGAEAPKASAATTNLEIQEVTKYYS
                     MNSYEVSQKESFNLSKGEELTVFVQNSGFPISYTVFDADNQVIGTYNANSPYGRVFKAQ
                     KDGNISVQFQAGVNSSYMKKMNFTAKFAVSKLNQQ"
     gene            complement(15935..16150)
                     /locus_tag="CN325_RS04815"
                     /old_locus_tag="CN325_04815"
     CDS             complement(15935..16150)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167046.1"
                     /locus_tag="CN325_RS04815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04815"
                     /product="alpha/beta-type small acid-soluble spore protein"
                     /protein_id="WP_001167052.1"
                     /transl_table=11
                     /translation="MQIRENNNSNEILVAAAASAIEQMKYEIAQEFGVTLGPDSTSRAN
                     GSVGGEITKRLVRMAQEQLSGQYKIH"
     misc_feature    complement(16197..16209)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(16318..18060)
                     /locus_tag="CN325_RS04820"
                     /old_locus_tag="CN325_04820"
     CDS             complement(16318..18060)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078258.1"
                     /locus_tag="CN325_RS04820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04820"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_098390267.1"
                     /transl_table=11
                     /translation="MKKYWHKLSLLQKNVLLTVLVILTLVGSMGALSFNMFQSSMMSIF
                     ERQSFETGDAVLNQLDLEIVKDVAKDPTAQRVKKEKLTEQLDKAIKDMKSVGQTYVTGA
                     KLNDKAELQIVALDTKLANTVSVKPGEDYEQPTYWMKTYDKVIQTKQAQMTEVYEDELG
                     FWVTILEPVTDENKNIIAIVAVDLDASIIPLTKKQFMIQGLLFIIISLTIAITIQIFIS
                     RNSLSPLKDLQEGLRKVGEGDLSIKLNERSDDIGITNIYFNNTIKKFNSIIDKVRQTAE
                     QVSTSSQELSVSTKENSIAFKEIASAITGLNLGAHSHEYVVQKCLGIVQEMESKMKEIK
                     GAAKQVGNALEDMDQHSVEGKDLIKQIVNQMKRIKDTVQDVSSSIYAVEVRSKEIHEIL
                     TVITTISNQTNSLALNATTESSCAGEMGEEFSGVADEVRILAERTEASARDIAKLIGET
                     QAEAERAVRSIQKSSKEVESGITLVQSSGAFFEKISESAQSVTNQIKANSSNSRDVLEN
                     SQSIVQIVNELSHIANTYECSSSNVEISMKEQEMYVQDIAELANSLNWLSQELQELIGG
                     FKIK"
     misc_feature    18667..18680
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.74"
                     /tool="antismash"
     gene            19042..19521
                     /locus_tag="CN325_RS04825"
                     /old_locus_tag="CN325_04825"
     CDS             19042..19521
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913866.1"
                     /locus_tag="CN325_RS04825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04825"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_098390268.1"
                     /sec_met_domain="Abi (E-value: 2.4e-14, bitscore: 45.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKINRFMFALPTISFIFLILLGSFLFVIPLDLFLPEIQKNLIT
                     EAPLILQVLLGVLAAPIYETVVFQVFLFWLLSWIPYIKNRDYLIILIASIIFGLNHQYG
                     ITYIVGTTIIGLLYNYAYWVYKKKNAKYQVTMSAFGVVFLIHLLHNSIAFIASNL"
     gene            complement(20239..20649)
                     /locus_tag="CN325_RS04830"
                     /old_locus_tag="CN325_04830"
     CDS             complement(20239..20649)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083130.1"
                     /locus_tag="CN325_RS04830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_04830"
                     /product="hypothetical protein"
                     /protein_id="WP_098390269.1"
                     /transl_table=11
                     /translation="MIKKLIISSIALGATIGVSKPTFATTIHSPSQFKETRNVHVQSLY
                     SPWQYLGKTSRKLQIKSKDPKVLAFELAKEAPFYEEELVDICSEILDANVDVVYWTSKE
                     WVRFEEGNYEFKHEIKIFRDKERQQLITTLES"
ORIGIN
        1 tttcttttga accctgtgga tttataggaa taataccact tatttcattc ttcaatgaac
       61 taataatggc agggccattt gctttttttt caactaattt cggaatggac tttttaaaac
      121 cagaattccg aagaatcgac tcatatttat gatgaaaaac aacaaatgct ttctttgttt
      181 ctaggaaatt catttgcgct ctcacttgat caattaaata tttgtctcca tctatttttc
      241 cccaaatctg tccaaccaca aatgaacttt tatttgtagt attatcaaaa gccatatccc
      301 aggaagtaat aatttgatca aattgttccc aatttggtaa cacatcataa tattgaaacc
      361 agttcctttt aaaaatattc cctatatcac tcgatggttt ttgttgccat aaagataacc
      421 aagagcgtgc agaggaaaac ttctttttat cttcataata attttggcca tagtgttcaa
      481 cccataaacc tctgcctatt tctctgttca atggatcatc ccttgactct gctatagcag
      541 gaattgataa cacagtccat ttctcctgtt ctttctctaa caatctacca gctaaatcgt
      601 cctcatgcca tcgcgtcaaa attagaatta cctttgcacc tttttgtaaa cgtgtagata
      661 aagtgtcttc ccattcatcc catagtctat ttcggtatgt aattgattcg gcctcttggc
      721 gatttttaat ggggtcatca ataattaata aatctgctcc ttcccctgta atcgaaccac
      781 caactcctac agacaacatt ccaccagagt ggttatgtag tgcccaatct gttacggaac
      841 cttgtcgctc atcaattcta atattaaata tttctttacc aaactcttca atcttagcac
      901 gatttcttct accaaacttt tcagctaaac ttgatgcata agatacctct ataactctct
      961 tatttggata ctttcctaaa taccaacttg gcaatgtttc tgttatagac tgtgattttg
     1021 aatgcctagg tggcataaac accattaatc tattagtcga taatttctct tcaattaaat
     1081 cttggcaaat ctttgttatt aattttgtgt gctttgcatg tttatagaat cccttatgtg
     1141 tatactgaac atagaaaggg gtagttcact tttgccaatt ccttaaatgt attttcatct
     1201 attaacttat gcacattcat ccgtgtcatg attgtaattc tcctccttga actttctcaa
     1261 ataatttcat agctaaatca agcatttcct catcacaccc aattttcata gccattttat
     1321 tatgctctac tttcatttct cctgaatgat ttacatttgc ttgcaattga tcttttcttc
     1381 cccatttagt tgggaatttt ctttctaatc tccatgctgc ggctttccaa ttagattttg
     1441 catgctcccc aattgtctca acgtctctag cttcactaaa tgctaatgcc tgatcaattt
     1501 ccatgactaa cttcacataa atcttatctt ttctcggtac tacttcacct gtcttttcac
     1561 tcgtttcaat tgccctacgc ccttgtttta accaaacata aactatactt ctacttattc
     1621 caactaacgc acatgcggtt tcaatataat tccctacttt aatatattgg gtcaacctat
     1681 ttatcagctc atcattcaat ttcattggtc gcgccactag cattccctcc cgttttaact
     1741 catcatttgt atttcttttt ctaaacactc aatacatatt gttgttatat tgtcgtcaac
     1801 tacctcacga attaacattt gttcacaata ctgaattgtg attggaaatt tcaaaaccca
     1861 caaacatttt tcaaggcaaa ttgaacatat tggcatagta tctatatctt gttctaacat
     1921 ctaatcgcat ccttctgtag tttttcatgt actactgcct attttgtagt aaataaaaag
     1981 atgccgtcac ttttaaaatc tctcatttaa tttatagata tcctttggat tactctttct
     2041 ttttgctagt atccattctt cattttttat atttcattta aacttatttt attactctct
     2101 atttataggt ggcactatgg tgacaagaat gtatttgtaa ataaaaaaaa gccttaacta
     2161 ctttcgcaga aaagactttt tcttacttgt ttagcaattt ttatttcaga tctatataga
     2221 atcgttttaa ttgtgcttct tgaaacattc aaatatttag caattttctc ttgtgtaatg
     2281 cctcttcctc ttgacatgat atatatttct ctttcatatt ttgtcaaagt agagagcgca
     2341 tcttctagtt ttattctctc ccattctgaa atgacacttt ctttgttttc atcatcccat
     2401 tcatatgttg tatcagtact acgaaaatac ctttgcatta acaaggaatc atatgatttt
     2461 tctcgttggt aagcagctct acgttctatt ccccgacgat tccccggcat ctttgcattc
     2521 ttcatccact ccaaagcata tgtgacatca ctaatcatac ttgttaatat tttattctct
     2581 tcttcttttg cacttatttt agcactctct agcttacata acgtttcttt atattggata
     2641 attaaatctc gcatatacca ttcccaccct tataacaaag caaaattgtt aaaaatagag
     2701 accatctaaa tctacattta atttccattt attttttctc accaaaaaac taaaattata
     2761 aaaaaatctt gcttaatact atttatcatt gctactttgt acttatatga tatatgtata
     2821 taacgattcg tttttatctc tttttcatca tttttttaca taaaaataac cacctgtttg
     2881 tttacacagg tggttataat ccatattaaa aacttattca ttatgattag taatcttaac
     2941 actcctcaac ctcaatccct aatgcatatg catagttgta aaaagcagta tttctttttc
     3001 tataataatc tccctcggat aaattcaact ctttcataac ctcatatcta ttaactcgat
     3061 tctttaacaa atatttttga ataattattc tatcactttc aatatctagc ttttctaacc
     3121 ctttgttcat cgcaataata taattgaccc gctcttcttt cgcattttct ttgaatatat
     3181 tttctttcga gagtatcgtt tcgttaagat aattacactt cataaataat ctgtatttct
     3241 ttatagcttt caatacattt tcttttgtag cttctttatt taatactggt aattctatat
     3301 ttaacatgtt aagccccttt cttatcattt atccttaatc ataatttgaa tttcatatct
     3361 ctaaatcatt acaatgattt gctattaagg cttatatcct tcatgtatta tttcatacat
     3421 tgtattacta acatttattt tcttatcctt atgatttttg attaatttta ttaactcatc
     3481 actatttaat tcgtataatt gtttatcctt atatttgtaa attccatttt caataagttg
     3541 attaattaaa aataacttca tcttgctaca ccaccatatc ttcaacgaaa aattgaatct
     3601 ctatatcttt tgaattataa taacaaattg cgcccccatt aatcggaaca catcctacta
     3661 caatttgaga ttcacttcca ctttttacaa tagccacttt atacaattta ttatctcttt
     3721 caactacatc accaagtcta aactcattta ttttacgccc tttgatagcg aataattttg
     3781 cctgttcaaa taataatttt tcactttttt cagctttcct aatttttaat ttcgtactct
     3841 tttcaaaatg accataatta ttagagaact cctctccatt aatccaaaac caactaccat
     3901 gctttatttc tttttcattt tctttacaat attcagcgat gaatttttca cttttttcat
     3961 tttcaatata caatagttct ccttttcgaa ttgtttctct acaatctata aattcattct
     4021 caaaaaagaa attaatttgt tgatagcttt cttttttacc taaataatca gcaatcactc
     4081 tttcaccttc tattttccaa cacatcggtg tctcttgtac tgttgtaatc caatttgttt
     4141 tcattcgttt aattgcttca aatcctttat atgttctcat ttttaagatg cctccattta
     4201 attatttaaa acatattaaa taaacttaaa aactacttcc aatgtacata cgtgtaattt
     4261 ctgattaaat actctttcca ttcctcatat tctttcttaa cttccgaacc aattcataca
     4321 gtacaaattt cttgaataat atgtttttat ctacatatat attcttttct taaaaaggta
     4381 attttctctt acgcttatcc cttgtttttt taaattctat gtgtcgatat gtattaaaca
     4441 tacgagatgt aactctttca tcgtacgctt ttataattgc ctcacctgtt aaattcgttg
     4501 taacaattgt ttttttccct tgtcgtccat caaagagttt aaataacaca cgatttacaa
     4561 atgctgttgc ttttaaatca ttaatatcca tatcccctag ctctgctcct agatcatcaa
     4621 tgactaataa atccatagaa attagcatat ttgttatact atgctctgtt tcacaagatt
     4681 gcgtattaaa tgtcgaacgt atgtaatcaa agagttctga acttgtaaca tacataactt
     4741 tatccgaact ttgttcattc atttcatgcg ctatagagta tgcaatatga ctttttccgg
     4801 ctccaacttt ccccacaaga atcaaattaa atcgaatatc atttaaatag tctgtaagag
     4861 cctttttagc taaaattaaa ttcttttcat cctcttcaca ctctgatata aatgtcgaaa
     4921 atctagctaa tttaatagtt tcatctttaa taagactctg atcgtaaaat atacttttac
     4981 gttttctttc ctctttctca taacgaaaaa cattcatttc tttttctaac cttctatttt
     5041 cttcttctaa acgacatact ggacaaatcg tttcaccctg aatctccatc aatcttacca
     5101 ttcgcttcct ctcctgatta catatcacac atgtttcaga aaggaatttc attttcttcg
     5161 aaagactttg tactatatct gttacctttg ttaaagccat ttgatttcac catctttctc
     5221 tgctgcaaat atccctcaaa tttagttcca aacaaggttt ctggtcttaa atattttgcc
     5281 tgttctgtat aaagccattc tttcgccttc gtctcaataa cttctttaaa ttcatttata
     5341 ttaaatccct cttgtagtct agatttaatt aacatttgtg tctttttagt tgaaatacga
     5401 taacttgtat tacatacact gttgagataa ttaattatct ctactatatc tttttgagtg
     5461 gtattctctg agttaatctt ttgtgtagtc tctggtattg gttgagacat attatcattt
     5521 tccatcatga caatatgttc ttttcgttga gacaatttgt cacaatcgtt atctatttct
     5581 aattcaacta gtctgtcata atttattgaa taccattttg ttttatcaaa ctttaatttg
     5641 ttatagttac cgcttatcaa taaattaaac tcttctagat ttttaacaat acgtttcaac
     5701 gttctttcat tccaaaacgg gaattgttta tgccaatttg taatgctatt atagacccaa
     5761 taacgatcat cataataatg tttcgagcgc ttgagccaat aatgtatttg ttgaagaaaa
     5821 attgcctcgt tcaatccaat cttacttgct aatcgaggta atactaataa tggctcatcc
     5881 tgtattagca aactactcat tttatcttcc tccatatttt tcttgaaatt tatatattaa
     5941 acttcttaaa tattaaaggt tttattctcc aaaaccttta aatttcccaa cctattaata
     6001 cttttatagc ttgattagct tgcttccttg taagatcact cagtgattga attttaagtt
     6061 ttacttttaa tttatttttg atttcctctt ttgaaattac tccatcatat ttcaatgcta
     6121 ttatatgcat tttggcataa atcattttta actgtttata cgaaagcttt tccgattcaa
     6181 aacaactagt atttctaaat tcttcattct cattagtact attgctgaca tatccttgtt
     6241 tttttgtcac tctaaaaacc atgattaatc ctccttacaa taggatttcc tataaggttt
     6301 gttttttaag acgatagtct ttcttttctt acaccacatt ctctgttagc caatttaata
     6361 aaaatgcttt cgtttcttta gccggaaaat accatgtccc gcccacttta aatttttgaa
     6421 cacgctgatc aaaaaagaat tctttttaaa cagtactcca cgacatgcac gttcttttta
     6481 aaaattccct tgtatcccaa aatacaaatt ctgcatccac ttctttaagc ttttcttcta
     6541 atttttctaa atataatctt ctgattgctc tttcatttac ttgaatattt agcattctat
     6601 atttcatctc gatttttata taccaattac actttagcgt ttcatttttt agatttcttt
     6661 ccttcttttc taagtaaaaa ctatatataa agtaccttta atagtaggat tattagatat
     6721 tttgtttaaa acacctcaaa aaacatccta taatccatat ataaatacgt gcatttttgt
     6781 cacaaattat ttaaaaaaag atcagggaat aattcttcta tagatttctc taaatagcac
     6841 gataacatat gtgcctcttt cagagtgaat tcacttttat tatgttcttt tgcccaatat
     6901 gtacgtggag aaacattaag aaaatcagca acttcttcaa tagtttttct ctttaatttt
     6961 ctttctaaaa atatcatctt gtgcattttt gtcacctctt ttcaaattca aatatagtac
     7021 tacgtgacaa aacagtcaag aattttttta ccaaatcacg aagaaagttg catttttgtc
     7081 acaccaatta tataatcaat caagacggag gtgacaaaaa gtcatgaaat cattcggttt
     7141 aaaattatct caattgatga agaaaaataa tatgacagac gagcaattag ctgaattatt
     7201 atctgttagt agaactactg ttttgcggtg gagaaatggt gaaagaagcc ctaaaatgtc
     7261 aaaaatatct caaatcgcta agatattaaa tgtctctgca acctacttta ttgatgaaaa
     7321 tgaatcctat tgtcctgaag atcacgtaat taccaaacgg aatattccca tttatggtac
     7381 aatcgcagct ggtaaaccaa ttgaggctat agaaaatgta attggggata tacaggtacc
     7441 tgatatcatt ttagataaat atggatttga aaaactatta gcacttcgta taaacggaga
     7501 cagtatgaat agaattgtac atgatggaca tatagctgta cttgagagga caacaaatat
     7561 aaataatggc gacatagccg ctgtactcat caacggatat gacgccactt taaaaagaat
     7621 ttacaaaact aataatagaa ttatcctaga gccagattct tttaatccta gtatacatcc
     7681 attaatgttt gattgtacag atatagaaaa ttgtccagaa ataaaagtag ttggaaaata
     7741 catttggagt tgtgcaccaa ttcaataata tttcatcaat gaattaagtt attttttaat
     7801 aaattttaaa gtaaagggga tttctcccct tcttttttat agcagggatt ttatcttggt
     7861 tactttcaga gaatttagat ttttcttgta tgctttatag gtgaattact cttctttcaa
     7921 ataaaagtgt tttaccctca acacgttttg cctcaagggt tggaacctct tatataggta
     7981 catttactga tcgcgttccc attggtgaac ttgtatgcgg gatatataca gtccactttc
     8041 ttctcttaaa caatcattct tggttacttt ttcttactca atataaaatc ccctcctaac
     8101 tggctttatc ctattccata tactaccaca tcttatcttg cataagttta gataagattc
     8161 tatcctctct cattaatttg cgaagataat tggcatcaag attaattatg tttacaacta
     8221 ctttaatcgt aatcattttt tttaattgct ttatcactag atgatttgcg tacaaaaggt
     8281 acagattcaa tattatcgtc tattaaaggt tctagcactt attttacctt ttactaattg
     8341 tttccatgtc acctactctc cagcatttta attaaatatt tttattgatc caagctttaa
     8401 atcgtcagtt tcaactatag aaattgagaa gggatgaata aaaaagtggg tgaataatga
     8461 tgaaattttc gagtcgtttt ttataaaact tagttttgga aaagaaatac tgagaagaaa
     8521 tgggaagcta ttaattagag gcaacatgga ttaaagaaca tattgagtaa aaaaaggcag
     8581 tatacaccgc ctttttttat ttcatttaag gatgtttctt taagaattac tacacgaaaa
     8641 aggcattgtt aaatttaagc aagaattttt ttcttattac tctcaatacc attaagaatc
     8701 cctttatatt ttctagaaaa tataattgat aacattacat aattaaaaaa taagctaata
     8761 aatacaccaa atatattcaa gttgaacaca taaatggtaa taatcatcat tacaaaagta
     8821 attaaattta ttatagctgt ttttattaaa acataattac tttgccctat agcttgtaaa
     8881 gcatatttat aaacattatg taacggatta aagatattag ctattataat aaatgtaagt
     8941 atacttgcag cataattaat taaattcgta tcatttgtaa taaaagctac aacctcatat
     9001 tttaaaaata caaaaataat acttaaaaac atgtagaata ccataataag tcctaaagtc
     9061 accttaggta gttcctttaa atctattaat tgtttagagc cgtacctttc actaactaaa
     9121 gttagaatag cagaagaata catatacatt ggaattaaaa taatacttaa aatttgagaa
     9181 actaataagt atcctgataa ttgtatatct cctgttcgag caatcatagc atttacacct
     9241 ataatgaaaa taccgccttc taaaatctct tgaccaacta gagaggtgct ctttttacat
     9301 aagaacttta aattattaat atatatttta atgttttgaa aggtaatttt taaatgtttt
     9361 ctacacaaat acatataaat aattaaattt atacttaaag caattatagt tgctattgcc
     9421 gaaccactta ttcctaattt cggaaatccg aagttaccaa aaatcagaag ataatttaat
     9481 attacattca agattgaggc taccgttgaa ccaataaaaa tccattttgt ttcttttatt
     9541 attttaaaga aagtcgaaaa cgtaaataat aataattgaa ttaatatata tacactcata
     9601 atagttaaat attgaataga gtcctttaaa atatttcctt caaaaccaaa aactatagat
     9661 aataaaggcc tttgaaatat gagtaataac aaagccaacg aaatacctat aattatatta
     9721 agaaaaatag aagatataaa ataattatta aatgatttta tatcttcttg tcccatgctt
     9781 cttgatccat aaatattaaa ggaaacagac attactccta atatacctgc aaatgtgaat
     9841 aaaagtgaac tcactacacc tatagctcca taagcttcaa ctgaaattct accgatcatt
     9901 gcttgatcta ccaatttaat taacaaccca gctattgaat tcacaactag tggtacagct
     9961 atatgattga tttctttaat gctgttaaga taattaaatc tcatgctgat agctctttat
    10021 aaatatcaga ttctattaaa ttagaagata taatacttaa taaagggaag tctaataaaa
    10081 attcccttat tgtttcttta ctcatatctt cgtttatttc atattcctct gatattttat
    10141 ccgcaatgaa ttgaaaatct tttcctttag aaatataata taaaatttct gcacctataa
    10201 agtttgttac gtagtattct agggcaattg gatcaaaaaa aacatattta tcgccctcct
    10261 gtctgaatat tatatttttc ttaccatgaa taataaaaca tttaatatca tccatttgct
    10321 acactctcct caaaaaagca actattatcc gaaccatata ttgagtttgt taaattaaag
    10381 gcagaagacc tacatccccc tccacaccac ttatgactac aggaaccaca tttaccatta
    10441 atattatcaa atgatatatt tcttaattta ttgaatacag atgattcatt ccagatttct
    10501 ttaatggatg tactttttat gtttccagct ctaaattggt caattcccat cattaaatca
    10561 caaccaaata catcaccatt atatgcaata gaacaagctt tcacacctgc ttgacatgat
    10621 atttctcttt cctttgtatg tatatccgtt aagttcagat cttgatccca aacagataac
    10681 aaatctaaac gattataatg ttctaaagga aaataatata accaaaacac aggactttca
    10741 ttaggtggaa ttattttgaa atttaattta atatcccccc tacttttcat ttcagataga
    10801 tttaaaaaca taggatacca attattctta tccgctaata tacttccgtc cgaagctcta
    10861 cctgttggac aaacaaccat gactgtcata taagttatcc ctaataattc attcagttta
    10921 attgtattaa taagatcatt aacattggtt ttatttaatg taaaaagagt agacactggt
    10981 aaattatatt tttgtaaatt tttaatacct ttaattgtct ttttaaaact accatgaccg
    11041 cggattatat cgtgtacttc tggacaactt ccatctaaag taatacatat tctatcaaaa
    11101 tcaaattttg ataatttact tgcaatttta tcacttatta aaattccatt agagttaatt
    11161 attttagcaa atttatattt ttgagttgca cttaagatct caaaaaaatc atctctaata
    11221 aaaggttctc caccagttaa ggaaatccta tgaacgttca tgtcatctaa gtcttgaaat
    11281 aaattattta aatgatttag atccatctct tcattttttg tttcaaacgg actagatgat
    11341 gcatagcaat aatcacattt taaattacat ctattagtaa tacttatatc tactaaagaa
    11401 ggagccgaat agtaatttct cacaaaaaca cttcctttca tatactaaaa gttaatgtaa
    11461 acaggagtag attaaattct actcctgtaa atctaaatta gtgttttccc caaacgctct
    11521 gacgaatagt tacaggtttt tcaaattcct ttttcatatc aaacgcctcc tttagaaata
    11581 atattataaa tttattagat tagtaattat caattgtgaa tattttccca ttcacatcat
    11641 cactataaca tggcttctat aatataattc tcaataattt tgaatatttc acagatcctt
    11701 ccaaaacata ttcatacatt gttttaaact aaagttttat taattatatt tgcccttctt
    11761 taaataaata taggtaacat aaattttttt ataattctaa attagtgttt tccccaaacg
    11821 ctctgacgaa tagttacagg tttttcaaat ttctttttca tatcaaacac ctcctttaga
    11881 aataatatta taaatttatt agattagtaa ttattaattg tgaatatttt cctattcaca
    11941 atatcactat aacatggctt ctataatttg attattgata attttgaata tttcgtgtat
    12001 atttttgaca catattcata aattatttta aactagagtt ttattaagca tattcatcct
    12061 tctttaaatg aatataggta acataatttc tcttataatt ctaaattagt gttttcccca
    12121 aacgctctga cgaatagtta caggtttttc aaattccttt ttcatatcaa acacctcctt
    12181 taaaagtaat attataagtt tattagatta gaaattatta attgtgaata ttttcctatt
    12241 cacaatatca ctataacatg gcttctataa tataattctc aataattttg aattttttgt
    12301 gtatagttcc agtatatatt tatgtcttgt tttaaaatga aattttataa atcttgttaa
    12361 aggaaataag acatttaaat tattaattta aatgtttacg agaaaaaaga gaatacccta
    12421 cccttaaaca aatagaaatg tcctaatacc atatctagga catccctcca ctttactcat
    12481 cttatacata acttatctaa atctttagac cctatacagc tctaacaatt aaacaaacct
    12541 aaaatatatc ttctgcctaa aacatagtat tattattagt tgtcttactt ggaatctctt
    12601 gtattacata ccaatgctcg acaatcttac catcctttat acgaaataaa tcccctatag
    12661 caactccctt atcttgagaa ttagctcgga aatgtacatg aagagcaact gtatcccctt
    12721 cagctactac acgtttaatc tctgcagagg aattagggct tttaacaaaa ccctccttaa
    12781 agaaatccat tgttatatct aatatttaat atcattttcc gtttaaaccc cttattttaa
    12841 ttttttactg atacattatg ttaaattgtg tgtggcaaga tgaaacaagc taataaatta
    12901 aattattgtt aggttagtta gtatctaatg atatgataat atcattagat acatataaaa
    12961 aggcatcctg ccttgtaaca gaaaaccttt tatgtattat taacctacaa acctaaaatt
    13021 tcaacaatct gacgtgcctt agcattatct ataaaataat gcatctctat ccctcttctt
    13081 tctgagcgga gtacggttcc cctcaatttt gataaatgtt gtgaaacagt ggactgtggg
    13141 agtctcaata tctccgttaa ctgtgtaaca ttgcagactt tatgttgcat taattcattt
    13201 acaatttgta atcgaacagg atgtgccatt acttttaata catctacatc gtcttcatgg
    13261 atttcagcta gatttctttc agatattaat gttatcattt cgcattctcc tttattatta
    13321 atttctattt tccttttatc cttataatta atacttatag ctaattacca tttgtcctgt
    13381 tgagaaaata tattctcttt ttaaaacaaa aaggacacca attcataaaa acgtttttta
    13441 ctgctttaat gaattgatga cctctaattt tttgaccaga gtatatcttg ttttaaagga
    13501 tattttcaat tcctttttct caaatctagt aaaaaatttg tattttcttt aaaatccata
    13561 ttaagaatat tcttcaaatc ctgaaagcat aagtttgcgg caaacttatg cttcctatca
    13621 cattccacac caatcaggat aattaacact atcaatgtag tactaactat cttaattgaa
    13681 tattagtaat agtgagtcta aatattatca attcacttta tattacatgt atgtaaaaat
    13741 aatgacatga taagcttttt caaatttttc tcctgataaa gatttgaaat tagcatttca
    13801 atactctcct tactgttaat atgcctggaa aaagaaccct atagggttct ttttctcttc
    13861 attcccaaaa atcccataaa aaaagaagag ggatatctcc cctcttcacc aataaaatcg
    13921 aacatattta caattaagga agggcataca ttcatcaaga gacgaaatga acaataatag
    13981 ttcacctagt gaattataac ataaacccaa ttccattaat agttaatatt aacatttatg
    14041 gaataattgt gacataattg ttaagtatct taatattaaa aggctttata tatatgtaaa
    14101 ttgaaagtgg atagtgtaag aataaaattt aagggggata taccatgttt aacaaaaaac
    14161 aaatattcgt aacaacggta acaactttaa cactaggatg tggatttaca ttcggattaa
    14221 caccggcctt tgcagattct aacaagattt ccgccaacaa tattcctgtt cattctattc
    14281 agaaccaaga acaagaacct tttactggat atgtcatttc agtagagaac aattatttag
    14341 tagttgctgc tacgtctaca aaagatgaag ctcttgctta tcaacatgat tggtgggatc
    14401 tagtttctca aaataagatt ttaagggtcc ctgtttcaga tggtgcaaac tacacattag
    14461 gtgagaaatt aaatgtatat gcagctgcat ggactaaatc tctaccacca atagctgtta
    14521 tgcctacaat tgaaaaagta tttcagtagg taatatttcc aataattaag ttatcccata
    14581 aaaaagagtt gaataacgac tcttttttta ttctttttta cctttctctg gattccttac
    14641 gttctcatac ccctaatatt taataacatg cttctttctc actagctaac gcaattttca
    14701 tcttaggaat tattaaccat attacttatt tgaatcctta tcataatttt aaaaaatatc
    14761 tattataaaa taacgtatca ccacctacat ttacctatac gaatttaaga aataagtaat
    14821 tcaaaaagaa aaataaaaat actcaacaaa gaatatccat ttgtttcttt tcgttggttt
    14881 tccagcatgt tgtatataaa aaaataaagc aatgcctgtc atagtaatta aaaaaatttg
    14941 atagtaatca atcatctgta ataccccctc caaacaaaaa taagaagccc ctttttaaag
    15001 agacttctca tttctaatac aaacgacata cataggataa atatacacaa tattatcagg
    15061 atggtttgct ttgttgctcc tctagcataa catacaatat ctcatttttg tttaataatt
    15121 ccaaattata aaactttatc aacattaaaa tatttcattt aaagcaaacg aacaaaaata
    15181 aactcaacga aatatttact tataaaaccg acgtatgtaa aaaaacagct acaattccat
    15241 tcatagtttt aaaaatctgt cctcctcttc ttctaagaat attctaaatc tcagatagat
    15301 tgtcttatat cgacacctta tgtatgcaga attacatatc aaactatatt gaaaatcatt
    15361 ctcattgtaa ctataatggt ttcaagaagt ggtaatttca cttccttttc aaatctcaga
    15421 atatattaaa ggaggaacta gcattatgaa aaaagctatt ttagcagggg cactaggaat
    15481 tgcagtacta tcaggtatga atttaccagg agcagaggca ccaaaagcga gtgcagcaac
    15541 tacgaattta gaaattcaag aagttacaaa atattactct atgaattcct atgaagtttc
    15601 tcaaaaagaa tcatttaatc ttagtaaagg ggaagaactt acagtttttg tacaaaattc
    15661 cggcttccca atttcttata cagtctttga tgcagataat caagtaattg gcacatacaa
    15721 tgctaattca ccatatggtc gcgtattcaa agcacaaaaa gacggtaata tttctgtaca
    15781 atttcaagca ggagtaaatt cttcttacat gaagaaaatg aatttcacag ctaaatttgc
    15841 agtttctaaa cttaaccaac aataaaaatt ttaacgatcc tctttaaagg caaattaaaa
    15901 aggtatatcc cttcaatggg atataccttt aactttagtg aattttatat tgaccagata
    15961 actgctcttg cgccatacga actaaacgtt tcgtaatctc tccacctact gaaccatttg
    16021 ctcgtgatgt tgaatctggt ccaagtgtca cgccaaactc ctgagcaatt tcatacttca
    16081 tttgctcaat tgcacttgct gccgctgcta ccaaaatctc gtttgaatta ttattttctc
    16141 gaatttgcat ttctaacaca cctccattta tttggtaata taatgctcta tttccattgt
    16201 aatatgcaaa agaattactc ttttaactct tttaactatt ttacatatat atctaagctt
    16261 tcatccctta tgtgggaata aataaaggta taggtcatac ctacaccttc ttctatccta
    16321 cttaattttg aaccctccta ttaactcctg taattcttgg gagagccaat ttaaagaatt
    16381 tgccagctct gcaatatctt gtacatacat ttcttgctct ttcatactta tctcaacatt
    16441 actactgcta cactcatatg tatttgcaat atgtgataat tcatttacaa tctgaacaat
    16501 agattgacta ttttctaaaa catctcttga attactcgaa ttcgctttaa tttgatttgt
    16561 aacagattgt gcagattctg aaatcttttc aaagaaagca ccactacttt gaacaagtgt
    16621 tattcctgat tcaacttcct ttgaactctt ctgtatggat cttacagctc tctctgcttc
    16681 agcctgggtt tcaccaatta atttagctat atcccttgca gatgcctcgg ttctttccgc
    16741 taatatacgt acctcgtccg caacacctga aaattcttct cccatctctc cagcacatga
    16801 ggattcagta gtagcattta aagctaatga atttgtttga tttgaaatgg ttgtaattac
    16861 agtaagaatt tcatgaattt ccttagatcg tacttctact gcataaatac tagaagatac
    16921 atcctgaact gtatctttga ttcttttcat ttgattcacg atttgcttaa tcaaatcttt
    16981 tccttctaca gaatgctggt ccatgtcttc caaagcattg ccaacttgtt ttgcagctcc
    17041 tttaatttct ttcatcttac tttccatttc ttgaacaatc cctaaacatt tttgcactac
    17101 atattcatga gaatgtgctc ctaaatttaa tcctgtaata gcacttgcaa tttctttaaa
    17161 ggctatgcta ttctcttttg tacttaccga caattcctgt gaagatgtcg acacctgttc
    17221 agcagtctgc cttactttat ctataatact attaaacttt ttaatagtat tattaaaata
    17281 gatattagtt attcctatat catcagatct ttcattcaat ttaatactta aatccccttc
    17341 accaacttta cgtaaccctt cttgtaaatc ctttaaaggc gatagagagt ttcgtgagat
    17401 aaatatttga attgtaattg cgattgttaa tgaaattata ataaatagta aaccttgtat
    17461 cataaattgt ttctttgtaa gaggaataat agaagcatcc aaatccactg caacaattgc
    17521 aattatattt ttattttcat ctgtaactgg ctctaaaatt gttacccaga accctaattc
    17581 atcttcatac acttctgtca tttgtgcctg ttttgtttgt attactttat catatgtttt
    17641 catccaataa gtaggctgct cataatcttc acctggtttg acagaaacag tatttgctaa
    17701 ttttgtatcc aaagctacta tttgtaattc agctttatca tttagcttgg ctcctgtaac
    17761 atatgtttgc ccaacacttt tcatatcttt tatagcttta tctaattgct ctgtcaattt
    17821 ttctttcttc actctttgag ctgtggggtc ttttgctaca tcttttacta tttctagatc
    17881 taattgattt aataccgcat cacctgtttc aaaagactgc ctctcaaata tagacatcat
    17941 actactttga aacatattaa aacttaacgc tcccatactt ccaacaaggg tcagaattac
    18001 taataccgtt agtaatacat ttttttgaag caacgatagc ttatgccaat attttttcat
    18061 tgatttctcc tttcttattt tcaacaatac aaaaacaaag tagtaacata ttaagaggtt
    18121 ctctttctgt tattaattta aactttaaaa tagcatacta atcgttcaac caaacgttcc
    18181 aatttttttc atttacaatt tcatctttta tatgtccagc tgctcctgga aatctattaa
    18241 aaggaagacg taatacttct accacttcat cttttctatt tgtactgatt tcttctaaat
    18301 cgatgatatt aaaggatttg cctataataa ttgctataat gtttaataga cgactaagaa
    18361 tatttaaaat tccatattta tctcctaaag attttcaaat tagatttgtt tcagtacctt
    18421 cagcgaggat tttttataat atcgttagtt ttaaataaag ataagaattt ttaagagcct
    18481 catctttagt tatttttatc ttgcagaaca ataaaacctg aaagtttaat tcaatctcct
    18541 attttataac ttttttcctt atttttctat aacattataa tatttacctg tacaatctga
    18601 actcggactc ttttggcctt tacccttcaa ttgtcttaaa ttcatatgag gtagcgcaga
    18661 aagtaaattt ttaataaaaa acttttgtat taaaaaatgc aaaaatacat actccttcaa
    18721 aactatatgc acttaaatat tcatacagta aaataaaaag tacaagcgtg tcctatacag
    18781 catatttcct taacgggctt gatattatat tcattataaa attggtgtga ccttaatatc
    18841 tcactaaatt ctttaatatt ttaatattaa caatatagtg ttaatatatc cctactttat
    18901 cgctacacct acatataagc caagaattca attacagagc ggttttcatc aatagtagac
    18961 aaaaacatgt caaacaaaaa gagactcaat tatttattac ttttcgtata gatgtaataa
    19021 aaaattatag gagaaatata tatgctcaaa aaaataaata gatttatgtt tgctttgcct
    19081 acaatttctt ttatttttct tattttatta ggatcatttt tatttgtaat accattagat
    19141 ctattcttac ctgaaataca aaaaaaccta ataacagaag cacctcttat tcttcaagtt
    19201 ttattagggg tattagcggc acctatatat gaaacagtag tttttcaagt atttttattt
    19261 tggctattaa gttggattcc ttacattaaa aatcgcgatt accttatcat tttaatagct
    19321 tcaattatat ttggattaaa tcatcaatat ggaatcactt atatagttgg tacaacgata
    19381 ataggtcttt tatataacta tgcttattgg gtatataaaa aaaagaatgc aaaatatcag
    19441 gttaccatgt ctgcttttgg ggttgttttt ttgattcact tattacataa ttctattgct
    19501 tttatagcat caaatttata aatgttttaa aggtaatata gattaatgaa ttatgtttgt
    19561 acttattaaa gctaagagac acgaaataaa agttaaagag aggctaattc actaatactt
    19621 ctaaatagtc ttgtttcagt ttgtttattt gaagaataaa agagagggat ttgtcaggta
    19681 gacagtattt tcaaaacaca gctaagccac ctgagtctat atttgtatgg actcaggtta
    19741 tttaatttct cttgaaatct ttgatgatta taacattgta tatatttgcg gacttatgat
    19801 agatgaagaa gtctttttta tgtgcattat cctaaaagtt ttactttcgc aacatacttt
    19861 ccttaatttt tctaacattc catcctcttc ttccaatcgt ttagtcttag tacccgaacc
    19921 tttaggtttc attctaccta aacataaccc ttttgctttc ccacgttctt cttctagttc
    19981 tttagtacct aaagtttcga atcatttcat ttaacatctt acaattggat aataaatgtc
    20041 tatttctttc ttaacagttt tatatcttct tttaagtata cacctacttc cttttccttt
    20101 cattttgcat agcaagtaat tctaatttac cccatagaaa aatcccctcc ataataaata
    20161 ggttaatgtg ttttcttttt cctatctact atgaggggag aatagcatac taaagatagc
    20221 ttcttttttg taaaagaact aagattctag tgtcgtaatt aattgctgac gttctttatc
    20281 tctaaaaatt ttaatttcat gtttaaattc ataatttcct tcttcaaatc taacccattc
    20341 cttacttgtc caatatacaa catctacatt tgcatctaaa atttcagaac atatgtctac
    20401 taattcttct tcgtaaaacg gtgcttcttt tgctagttca aaagctagta cttttggatc
    20461 cttactttta atttgaagtt tccttgaagt tttccctaaa tactgccatg gagaatacag
    20521 ggattgcaca tgaacatttc gagtttcttt aaactgtgat ggagaatgta ttgtagtagc
    20581 aaatgtaggt ttgctcactc ctattgttgc acctaaagca atagaactaa taataagttt
    20641 tttaatcatt ttttcagccc ctttatttat tttggatatg cttcattttt atactacgtt
    20701 catgttcgtg taaatgaaga tgatttgaca tgagtcatca tttttttcaa aaactgtata
    20761 taaattaacc gctataaatt cacccaaaac aaaaaaagtt tccttatgga aacttttttg
    20821 ttttggatat acattatatg tataaaaatt tattttgaaa atatttactt atttgttgat
    20881 aaaattgtgt atggatattt tccctactat ttatctacac acatctcatg caaagcctca
    20941 ctacaacata aacaaattca tcttatgacc acgtttcttc ttacgaaatt aagtgattgt
    21001 ttcaatagct ggtttgggaa tcatagaatt actttctttc ttagccctat tattctgttc
    21061 tttttactaa aattccaata tccccattac ttcttttgta aatagtttaa aatcagttaa
    21121 atgtttttca ataatttgac gaacaatatc taaatttaca ctttgataat catgaacagc
    21181 aatatttcga aatccaacca tcgcctttaa cttatttgcc agctctgcgc taagtaatcc
    21241 tgctgtaacc aataaatcaa aggcctctcg actagattgg ggtagtccta attttttccc
    21301 tgcaacaata tgcattgcta aatcaatact cgcttcacaa gctctttgta tattcaatat
    21361 tattgaatct tgttttgtaa agtcctctaa attttcaggg tcatttccat atacatcttg
    21421 gat
//
