LOCUS       NZ_NTSF01000004        23507 bp    DNA     linear   CON 02-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS021634
            AFS021634_110_H4_Contig4_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTSF01000004
VERSION     NZ_NTSF01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 246156)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 246156)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 48.88x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002563165.1-RS_2024_04_02
            Annotation Date                   :: 04/02/2024 02:22:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,903
            CDSs (total)                      :: 5,824
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 79
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 84 of 212
            Pseudo Genes (incomplete)         :: 133 of 212
            Pseudo Genes (internal stop)      :: 67 of 212
            Pseudo Genes (multiple problems)  :: 60 of 212
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:49:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 92617
            Orig. end                         :: 116124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTSF01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23507
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23507
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23507
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13507](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13507
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(558..1154)
                     /locus_tag="CN325_RS03765"
                     /old_locus_tag="CN325_03765"
     CDS             complement(558..1154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126039.1"
                     /locus_tag="CN325_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03765"
                     /product="DUF4878 domain-containing protein"
                     /protein_id="WP_001169482.1"
                     /transl_table=11
                     /translation="MQKIKKLLLLMMVVGLTAGVLAGCANPKDTTEEFLTAIQKGDVEK
                     ARTFVESDKEFNKLNEKTDDAEAKAMLSAITKNFKFEKLEEVSKKDDKAEVKVKITSAD
                     LSVAVTKAVGEVMPMAFASAFSEDKEQSEKAIEKTMTSTIVKNLADKDAAMATREVTLN
                     LKKDKDGDYKIVADDNLKEVLFANAKSLEKMFGGK"
     gene            complement(1313..1566)
                     /locus_tag="CN325_RS31295"
                     /old_locus_tag="CN325_03770"
                     /pseudo=""
     CDS             complement(1313..1566)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158817.1"
                     /locus_tag="CN325_RS31295"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03770"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQTVTSYPWVLRKTFSFALFCLLSVQFTL"
     gene            complement(1583..1946)
                     /locus_tag="CN325_RS03775"
                     /old_locus_tag="CN325_03775"
                     /pseudo=""
     CDS             complement(1583..1946)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036573.1"
                     /locus_tag="CN325_RS03775"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03775"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKKTIFYLLTCLLLVASTAYYNM"
     gene            complement(2077..2259)
                     /locus_tag="CN325_RS03780"
                     /old_locus_tag="CN325_03780"
     CDS             complement(2077..2259)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="CN325_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03780"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_001178297.1"
                     /transl_table=11
                     /translation="MQMMYAFGIGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVIM
                     FIAIIVMIVLISRSL"
     gene            complement(2288..2665)
                     /locus_tag="CN325_RS03785"
                     /old_locus_tag="CN325_03785"
     CDS             complement(2288..2665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="CN325_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03785"
                     /product="hypothetical protein"
                     /protein_id="WP_001109901.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGIIFLFMSGFMILTGIMTHSAPPAITYPLLGMMI
                     MSFCLSYLHPQFKEKDERMKLIRYKGMFVTFFALTAYYLLFSIGLNLKILTLSATELLN
                     ILMALTMSTVFISFVVLAKRY"
     gene            complement(2668..2877)
                     /locus_tag="CN325_RS03790"
                     /old_locus_tag="CN325_03790"
     CDS             complement(2668..2877)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428510.1"
                     /locus_tag="CN325_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03790"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428506.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGE"
     misc_feature    3268..3288
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.69"
                     /tool="antismash"
     gene            3701..6568
                     /gene="odhA"
                     /locus_tag="CN325_RS03795"
                     /old_locus_tag="CN325_03795"
     CDS             3701..6568
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="CN325_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03795"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_098390193.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLLEKAMSELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVLEGAKNRVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAV
                     ANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPDQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFQKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFIQEQLKSDYA
                     QVPPADTSDATIHVKVPNVVAKGIQPIDTGIELDSLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTETN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGM
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHVVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVYSN"
     gene            6702..7961
                     /gene="odhB"
                     /locus_tag="CN325_RS03800"
                     /old_locus_tag="CN325_03800"
     CDS             6702..7961
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="CN325_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03800"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_000569893.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESITEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAPVAVSTPAPAAEQPKQETAEAPKA
                     AAPNAEQTTGLQGLPNTNRPIASPAARKMARELGIDLNDVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKSPAPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVD
                     MSAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYD
                     IGIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGMKARDNKLSLKELQGGTFTITNGG
                     VFGSLMSTPILNSPQVGILGMHKIQVRPVAIDNERMENRPMMYIALSYDHRIVDGKEAV
                     SFLVAVKDMLEDPKSLLLEG"
     aSDomain        8085..8384
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CN325_RS03805_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="7.90E-58"
                     /identifier="RREFam011.1"
                     /label="CN325_RS03805"
                     /locus_tag="CN325_RS03805"
                     /protein_end="100"
                     /protein_start="0"
                     /score="183.5"
                     /tool="antismash"
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDW
                     IEKLMPMFNGNYSLAEITEGLPLPYQNRVFEIGEVLYENGFVRDANQDAPHELNS"
     gene            8085..10004
                     /locus_tag="CN325_RS03805"
                     /old_locus_tag="CN325_03805"
     CDS             8085..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="CN325_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03805"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_001061569.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1220.7,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     7e-57, bitscore: 183.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.5e-12,
                     bitscore: 40.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPIHAKLKVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDW
                     IEKLMPMFNGNYSLAEITEGLPLPYQNRVFEIGEVLYENGFVRDANQDAPHELNSSLLD
                     RYASQIEFLEADSHSGALKFETYRGANVLVLGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     DETNYDRIHELIERAYEVDNNVLLQEIDTTIDRPLHEVFEPFDWILYVSQNGDIDGLKT
                     VHTICRETKKNFIPAICLSTLGIAGPVVTENRDECWESAWHRLHETTLQNENSSDSFSP
                     ITSAMLTNVIVFELFKHVADDSYREKESQFFLLNYETLEGTWHPFIKHPLAADESFTID
                     TIENLSEKLEHRSNQHTSTDVFRFFDSLTSKEAGIFHVWDEQDSYQLPLSQCYIQVATP
                     LSDGPAPLLPLMTRSGLTHNEARREAGLTGIETYVAEIIHRLIPEHNDIGIGAGETMTE
                     GFYRALQQHLNNKLYERQSHMLEELTTIDLTDIHDKHCRFYYDALATIHETPKIAMSEE
                     ILSFPVVWVGINDRWYGASNINMTLALRNALQLSLFHIQNEEIPYRANILYDSSIILYD
                     TDSLRVEIQPEEEIPSVQSLQLALQHLEEHNFYPFVFDLAIEPFLKENLDGVYGVLIAK
                     EDGL"
     aSDomain        8115..8351
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CN325_RS03805_Thiopeptide_F_RRE.1"
                     /evalue="2.90E-13"
                     /identifier="RREFam004.1"
                     /label="CN325_RS03805"
                     /locus_tag="CN325_RS03805"
                     /protein_end="89"
                     /protein_start="10"
                     /score="40.6"
                     /tool="antismash"
                     /translation="KVNKDTFFLPDSNGGVYFRNNASSFRMDGDGIYDWIEKLMPMFNG
                     NYSLAEITEGLPLPYQNRVFEIGEVLYENGFVRD"
     gene            10001..11950
                     /locus_tag="CN325_RS03810"
                     /old_locus_tag="CN325_03810"
     CDS             10001..11950
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="CN325_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03810"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_098390194.1"
                     /sec_met_domain="YcaO (E-value: 1.8e-84, bitscore: 278.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.9e-143, bitscore:
                     471.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQNILLIGDGLLADYVHDQLCKQYSIIRQHTLTEELPENIHLAL
                     VLHDGSPSTIHHDAELIFRSNHIPWLRGFTSFGEGIIGPYIHPLTPGCSHCSDGRRFIA
                     GFDQKEMWELQRKYAFKADNVTRRDVRATQNGMLQMCHLICAETEKILTHNHSSLENEL
                     ILLNLQTLQCTRHSFLPDPLCPVCSNLPDDTADAAEVSLQPSLKVSTETYRCRSIHELN
                     TFLTRDYLDYRVGMLNGKMQHSLLPFADVIINMPLMFGNEGVAGRTHSFVVSEATAILE
                     GLERYCGMSPRGKKTNVHGSFHDLEEHALNPLTLGVHTNEHYNRDNFPFKPFDPDYEQN
                     WVWGYSLSQDRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMIQRLRTITGYELHAFNATMEHGIPSLWVIAK
                     NTRENGMNVVCAGGAHLDPIRALKSAIQEIAGMLLITDDELEHKREYYEKCLQDPYFVN
                     KMEDHSMLYGLKETEERLHFLLREDAPVQTFQEMNVSQSFDMDLTSDLHQLLNRLHQSD
                     LEVIVVDQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYTDEP
                     LTNERLNPHPHPFP"
     gene            11966..13507
                     /locus_tag="CN325_RS03815"
                     /old_locus_tag="CN325_03815"
     CDS             11966..13507
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016124293.1"
                     /locus_tag="CN325_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03815"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_001175545.1"
                     /sec_met_domain="PF00881 (E-value: 2e-08, bitscore: 28.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLDTFLHHLHFSIDEIMPNHEVDWKDAPLPYKLYRNVPTIPLSL
                     EIPLSLSNSSTTPTLNEIGHYLWYSFGVTQLCQLNSERNVLRRSIPSGGALYPNELYIY
                     LKIDDYPDGIYHYDAAHHRLILLREGNFDSYLADALGNRCNIHDCFGAAFVSTMFWKNF
                     FKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRALNHLLGLSEGEESVYA
                     VIPLSTEPETNWFHNDYRENKTVTSHELLQQIPPLAHEHFVRSKHVNEHPMITKINEAS
                     MIESTEHFQTLHHEEHYQHNTYAVQLPKVERLSYDFLQLCKKRYSPDADFILTKWDAAE
                     LATLLQEASLSFPYYNDLDGKYVNENARVSLYGCFYNVKNIKNGAYAYNSKTHSIQPIR
                     YGDLRYPLQSSMTMDNVNLFQVPLCLHVVGKKDYYTNALGYRGYRIHQMEAGILVHKLV
                     FASTAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQVPVGAYRARNWLKGALHS"
     gene            complement(13538..13948)
                     /locus_tag="CN325_RS03820"
                     /old_locus_tag="CN325_03820"
     CDS             complement(13538..13948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="CN325_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03820"
                     /product="DUF3908 family protein"
                     /protein_id="WP_000996808.1"
                     /transl_table=11
                     /translation="MAINMKTIEEWIVESNTRHEEDFGHVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGQEKDEYIEIEKLKYDDITNSNLKTNDKNTTLELKFA
                     NGQSINLDSLNDNYGTKNWLFARQIKSIFKLI"
     gene            complement(14246..14734)
                     /locus_tag="CN325_RS03825"
                     /old_locus_tag="CN325_03825"
     CDS             complement(14246..14734)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135035.1"
                     /locus_tag="CN325_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03825"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_000634324.1"
                     /transl_table=11
                     /translation="MIVALQKVQESEKEILRNLYALYLHDLSKFTMNITIGANGFFEYE
                     DLHMFWKNDGITPYFIKVDHSIVGFLLLLERPFLKKENDFGINDIFILNQYKGKGIGKQ
                     AVENLLEEKRGQYFVIELLKNVPAVSFWKKVYKKLNIEFDEREQLIDDEECLVQTFKI"
     gene            complement(14835..16169)
                     /locus_tag="CN325_RS03830"
                     /old_locus_tag="CN325_03830"
     CDS             complement(14835..16169)
                     /EC_number="1.8.1.14"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="CN325_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03830"
                     /product="CoA-disulfide reductase"
                     /protein_id="WP_098390195.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2e-66, bitscore:
                     218.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLP
                     YVISGAIASTEKLIARNVKTFREKYGIDAKVRHEVTKVDTEKKMVYAEHTKTKDVFEFP
                     YDRLLIATGVRPVMPEWEGRELQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNER
                     VEAIETDKGTYKADLVLVSVGVKPNTDFLEGTNIRKNHKGAIEINAYMQTNVQDVYAAG
                     DCATHYHVIKEVHDHIPLGTTANKQGRLAGLNMLDKRRAFKGTLGTGIIKFMDLTLART
                     GLNEKEAKGLHIPYKTVKVDSTNMAGYYPNAKPLYLKLLYRSDTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            16370..16798
                     /locus_tag="CN325_RS03840"
                     /old_locus_tag="CN325_03840"
     CDS             16370..16798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001978351.1"
                     /locus_tag="CN325_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03840"
                     /product="hypothetical protein"
                     /protein_id="WP_000332398.1"
                     /transl_table=11
                     /translation="MCAGLLAQFPEEPKEPKPALSLDQEFSINATIYSARAWLSNDETF
                     PQTIWKGSHFASASHAGKSILPIGTVKILNLSDDTITVTASSESDDTLKIVVPPHSEGV
                     LTSNALSDVQASTSGGASKVTFLFHIFFSRDPGSDKKP"
     gene            complement(16838..18073)
                     /locus_tag="CN325_RS03845"
                     /old_locus_tag="CN325_03845"
     CDS             complement(16838..18073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017672808.1"
                     /locus_tag="CN325_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03845"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_098390196.1"
                     /transl_table=11
                     /translation="MNVCTKCGVQFEDGVQFCQNCGMKRGSPVVKKNMSGGTKVGITLL
                     ALFVIAIIGLYLYGLSYYTQVAQVDRMITILQERDGEKLAEIVTADDPSVMITKESLTP
                     LFSYIKENPSYVNELKEYLRQGEKQRDGIERADFSLTKDGKYFFIFDRYKLKVKTYYTT
                     LLTNEKGVSLKMNGKEIDKTDDKKFEKQYGPYLPGNQVFQSEYKNDYVKLSREEKVVLM
                     KQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTALAGEEITWGPVATDGSAKIYL
                     ERNGENGRETTKVETVTALSSYNLPFQTKSTEKTVVYNITPPPTTGYVYNGFIFPDSDI
                     RKLTSTDLTYLSKEQLKIARNEIYARHGHIFQTKDMQAYFAKQSWYRENPYFTGTLTDI
                     ETYNIELIKSRE"
     gene            complement(18093..18878)
                     /locus_tag="CN325_RS03850"
                     /old_locus_tag="CN325_03850"
     CDS             complement(18093..18878)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650096.1"
                     /locus_tag="CN325_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03850"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_098390197.1"
                     /transl_table=11
                     /translation="MKCPSCHTEHAVEAKFCGNCGHSLTEEVVASSGKEEGQEQARAAQ
                     EKETRPNETVEQAKRFASGYFQFFKHALQAPTAIMKSGTIEVRNGIVSLVLVCFLGACI
                     FYRMMSAASAVTRTFAPDISTPTFFGESITVFFFLLILTLFVGFIIFVSGKMMKSSFSF
                     LEVFGIWGTIATPAILILVLSFLFSFLLIFFLPILLSVVATYIGISITVAVLKLDNGGL
                     DLVYTLIIANVLIGIATFIVLWSYISTIIQALTQGITGF"
     gene            19075..19908
                     /locus_tag="CN325_RS03855"
                     /old_locus_tag="CN325_03855"
     CDS             19075..19908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017762920.1"
                     /locus_tag="CN325_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03855"
                     /product="hypothetical protein"
                     /protein_id="WP_098390198.1"
                     /transl_table=11
                     /translation="MELVNSIFQILLTSIIQLFSLIGVIIVIGFLLGYLESLTRMYWSR
                     AFGRKGFLLTAWIGVPIHELGHAIMCVLFRHKIVATQFFPTDTSQGALGYIQHQYNQKS
                     VYQRIGNFFIGIGPIISGITALILLMRYFVPESYFLFNTTLEKTIASTSINVEMIQNML
                     LSTFVLLKSLFTIGNLLNPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNQLIGQVIKYNMYLIAFSSVALLFSCISTLVSFSFYKIRRGRSF"
     gene            complement(19923..20606)
                     /locus_tag="CN325_RS03860"
                     /old_locus_tag="CN325_03860"
     CDS             complement(19923..20606)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128607.1"
                     /locus_tag="CN325_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03860"
                     /product="YukJ family protein"
                     /protein_id="WP_098390199.1"
                     /transl_table=11
                     /translation="MPLKNYGVLKGTVIQSKIGKGKTPHYQVHLQGETGVDYRIAINVK
                     SQSYPSEVLYFASNNIRSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQMIPL
                     PPEKAGADNDLNEKIERYIKRAIEEKAIIYAFGERWGPEENTPDSYFHFKPGNGIHDIH
                     MNQGNVEKWKGDNGIWQDGGILIHFEKEEEWIGIFLAFQSQSWCTDEEGHARVPVEHCD
                     YKGNN"
     gene            complement(20697..22196)
                     /locus_tag="CN325_RS03865"
                     /old_locus_tag="CN325_03865"
     CDS             complement(20697..22196)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015727 - lactate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126004.1"
                     /locus_tag="CN325_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03865"
                     /product="L-lactate permease"
                     /protein_id="WP_000996262.1"
                     /transl_table=11
                     /translation="MAILLALIPIMMIFICLFLFKQTSLRSSLISYAVSVGIVLLSPTF
                     QLGISETVHATIKGWLICFIVGYVLFFGIFLFHLMNKMGYIDQVARFLEEVTQDRLLQM
                     LLMCFGICPLIESVSGFGIGFMVAAPIFLSLGYKPFQAVLLSFIGLLASSWGAMATGTI
                     IGSQLINMPLTTLGTNTALLSIPMFAYFVILSLHVVGGWQAVIEKWKEGVGFFLLFSLG
                     IYLSNAYVSVELAGILSSIVTITFGFLIIKLKGKSGQNLITEHAAATEREVSIIKIISP
                     YIFLTVCILLSRLVPALHDLFRSYAVLDLKSYSYKLELLYSPGFWLGMTCLFTIIFFRI
                     PSNIIKQSLSQTIKQWIPFAITTTMFIAISELMGASGMHSLLAKTAGDTFGTFFVFVAP
                     FIGAIGGFLTGSNAGSNAMFIKLQMQTAQNVALPWQYVTTLQNTASSVATIACPSRITL
                     GAYLCNIPYRENELLKKTTLMIFGAVLLVVVEVIVWYMLRN"
     misc_feature    22152..22167
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            complement(22306..22665)
                     /locus_tag="CN325_RS03870"
                     /old_locus_tag="CN325_03870"
     CDS             complement(22306..22665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016082428.1"
                     /locus_tag="CN325_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN325_03870"
                     /product="DUF4029 domain-containing protein"
                     /protein_id="WP_098390200.1"
                     /transl_table=11
                     /translation="MLRRKLLYLFLTVPLYAWLISMTKIELMALFLGYVFIFSNLNRIQ
                     EQSILEICLFSISIELFSIVSIVLLNELFRWIHSFELMKFGNVVLQVICAYIVFVVLDK
                     IIRQQSVFQDKRKWE"
     misc_feature    22695..22713
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.43"
                     /tool="antismash"
     misc_feature    23337..23351
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
ORIGIN
        1 gatgagaata aactctctga aatgttagaa ccaataaaac ttcagagagt tttattatta
       61 tttaatttta aaattaaaaa ctcgatatgg tttcgaactt tatcatataa atactgtaaa
      121 atagtgttcc ttcttaacta taggagcttg atttattcgt ctcgtgtcgg aaatatttat
      181 accctatcgt gtggtttagg gtgctatgca tcctctctct agcaagagga cattaaaatg
      241 tggaaaatag tcccccacta cactaaaaag ggaatgagtc acctcattcc ctttaccatt
      301 atacagacag ttaagaatat aattttgtgg tcacaaatgg tcacattcct tgcaataacc
      361 attgcttttt taatagaatt ccatttatac aaacccgtga accccccttt aaatcaacgt
      421 ttctcccgta gctcagcagg gagagcgcca ccttgacagg gtggaggtcg tgagttcgag
      481 cctctccggg gtcatataaa aaagagacac catatcaacc ttctacgtga tatggtgtct
      541 ctttttatct aattcaatta cttcccacca aacatcttct ccaaagactt cgcattggca
      601 aacaatactt ctttcaagtt atcgtcagca acgattttat agtcgccatc tttgtctttc
      661 tttaagttca atgtaacttc gcgagttgcc attgctgcat ctttatctgc taagtttttg
      721 acgatagttg atgtcattgt tttttcgatt gctttttcag attgttcttt gtcttcacta
      781 aaggcactag cgaacgccat tggcataact tctcccactg cttttgttac agcaacggat
      841 agatctgcag atgtaatttt cactttcact tctgctttgt catccttttt cgatacttct
      901 tctagctttt caaatttaaa gtttttcgta attgcactca gcattgcttt tgcctcagca
      961 tcatctgttt tttcatttag tttattaaat tccttgtcac tctcaacaaa tgtacgagcc
     1021 ttttctacat cacctttttg tatcgctgtt aaaaattctt ctgtagtatc tttcggattt
     1081 gcacaccctg ctaaaacacc tgctgttaat cccactacca tcattaatag caataatttc
     1141 tttatctttt gcacgttcat tctcctctta tcttttctag taagtcagca tcatacaata
     1201 ttatgaaact gacattacaa acatttttta gtatagcatt tatatgattc gttttctatt
     1261 aattcccaaa agataaagga ccttgcagca ttcctacaag gtccctcttc tatcaatctg
     1321 tatccgtagc acaaatgaac cacattttct gctccctact acccgctacc atccacacac
     1381 tccaatcaaa aatcataagt gacagccaac atatattaat agcagcaaat aataaatata
     1441 aaatgaaatc tctcttttgt agtccccctc tattcattac aatgtaaatt gcaccgatag
     1501 gagacaaaat aaagcaaagg aaaaagtttt tcttaacacc cacggatacg aagttactgt
     1561 ctgcatatga atcccctttt catcataata cttgcttcaa catcggcctc actaccctat
     1621 attcatcact ataagtttcc tttatgatta aaggtgattg aggacctttt tcttcctcaa
     1681 tcattgtgaa tacttctgtt ttctcttgta atgtattaga ttctctattt ttaataggtt
     1741 ttttacttgt tttaattttt tttgttactt caccaagttt ttgcccaact tcttctactt
     1801 tggcaggttc attcgtaaca tagtattctt gttcgtccca tactaatata ggtggcactt
     1861 gttctcgttt gttacatatt ataataagca gtactagcta caagtagtag acaagttaat
     1921 aaatagaaga tagttttttt attcatatac tacactcctt atctatcatt tcattggatt
     1981 atataatata agctatttat agtaaatgga tttagtggta atttttaggt ttaataataa
     2041 aaaaacctta ccgcagtaag gttccgtttt tacattctat agtgaccgac ttattaaaac
     2101 aatcattaca ataatcgcaa taaacataat aactaaacag ccgatcattt tataaaatcc
     2161 tcgtttcgtt aacgtcccgc cttgaacgtc tttacgaata aataagaata cagctaaaaa
     2221 taatacaagc ccaatgccaa aagcatacat catttgcata tgttaatctt cctttctctc
     2281 ttccatctta atatcttttt gccaaaacaa caaatgagat aaaaacggta ctcatcgtaa
     2341 gtgccataag tatattcaat aattcagtag cagatagtgt aagtattttt aagtttaagc
     2401 cgatagagaa aagaagataa tatgctgtta atgcaaaaaa ggttacaaac attcctttat
     2461 aacgaataag tttcattcgc tcgtcttttt ctttaaattg cgggtgcaag tagcttagac
     2521 agaaactcat aatcatcatc ccaagcaatg gatacgttat agctggcggt gcagaatgcg
     2581 tcattatacc tgttaatatc ataaacccac tcataaatag aaaaataatc cccataatta
     2641 caaagtactt ttgtgaataa ttcaccccta ttccccctct tcttttcctt cataaataaa
     2701 tacatgttct atcgttgttt gaaatgtttt tgctatttca aatgctagcg gaagtgatgg
     2761 atcgtatttc cccttttcaa ttgaaatgat ggtttgtctg gaaactccaa gtttctcagc
     2821 caacttttct tgagatagtc caaatttttt tcggtattcg accattttat tttccaagga
     2881 aatttctccc tcctcccata tatcgagtat atatgtaaag taaactttac gtcaaggttc
     2941 ctttacattt atcccaatca tttttcactc tatttatata gaagaaactt gttcgattta
     3001 agcacgtcta ttttgtaata aaacatggaa cactgtatgt aatcgttact atatttcctc
     3061 ctcacctttt ttaaaattta atatcttcat atttgtttta tccttttaaa atatttcatt
     3121 ctcttcttta ttagatgaaa tgtgttattg gttttacggt gtttttcgtc atatttatag
     3181 aaactaacgg gttatgaacc attttttatg tttaacaact ttttttgtag aaatccttca
     3241 ttttcctttc gatatttaac actatcgaaa taaagtttac gctaaattca taatttttta
     3301 ttttttatac tatattccgt tatattgttg tataatatct atgaaagcgc ttattatttc
     3361 aatatacata attcaaacta aattttatca aaacattcta actattgttc ctatatttaa
     3421 atgcaacaat tatagctatt agtgtaggca taccaaatat atccacccca tttttctgta
     3481 aaattacttt ataaagtgaa agattaactt gggtgataag ttattgtgaa tgttttttta
     3541 caaaacagat aagtaatagt gtttggtatt atgtaaatta ttgtaataac ataagagtaa
     3601 agaaaacatt tacattgatt attgattcat tacttattga aaaagagcaa aatgcacctt
     3661 tgtatggaaa aggattatat gcattgggag gtttaaacaa atgacgagga agaatacaac
     3721 gacaaaccct tgggccaagt tccacggtcc gaaccttggt tatgttattg agcagtatga
     3781 tctttacgta actggagcag gttctgttga tccggaatta caagagcttt ttgaaatttt
     3841 tggagctcct tcgtttcaag atgatgtcgt aacaggggac aacacagcaa cacatttttc
     3901 tcctcaaaac acaggtaaca ttgaaaaaat tcttaaagtc gttcaacttg ttgagcagat
     3961 tcgttctttc gggcacacgt tggctcacat taacccgatg gaagatgctg caaatggaca
     4021 atcacttctt gagaaagcaa tgagtgaact gagcgatgct gacttgaaag cgattccagc
     4081 gaaaacagta tggcaagatg caccagaagg tattcacact gcacttgatg taattcatag
     4141 attaaaagac gtttatacaa aatctttagc ttatgaattt tctcatatac aagatagtga
     4201 agaacgcgcg tggttgcatc aaatggtgga atcaaattca ttgcgtcaac cactatcaaa
     4261 taaaaaacga actgctcttt taaaacgttt aacagctgtt gaaggtttcg agcaattctt
     4321 gcataaaaca ttcgttgggc aaaaacgttt ctctatcgag ggcgttgata tgcttgtacc
     4381 tgttttagat gaaattgttc tagaaggtgc taagaaccgc gtagaggatg tcatgattgg
     4441 tatggctcac cgcggtcgtc taagcgtact tgctcacgta ttagaaaaac catatagtca
     4501 catgtttgct gagttcaaac atgcaaaaat agaaggcgca gtagccaatt ctggctggac
     4561 tggcgacgta aaataccact taggtagaga acaagtcgtt agtaacgaag aagttagcac
     4621 tcgcgtgaca ctagcaaata acccgagtca tcttgagttc gtgaatcctg tagtcgaagg
     4681 tttcgcacgt gctgctcaag agaatcgtaa aaaatctggt cttccagatc aagacacttc
     4741 aaaatcattc gtaattttag ttcatggtga tgctgcattc cctggtcaag gtattgtatc
     4801 tgaaacgttg aacttaagca gattgaacgc gtatcaaaca ggcggaacga ttcatgttat
     4861 cgcaaacaat gcagttggtt tcacgactga tagctatgat tctcgttcta cgaaatattc
     4921 aagtgacctt gcaaaaggtt tcgatattcc gattgttcac gtgaacgctg atgatccaga
     4981 agcttgtctt gcagctgcta accttgcgat tcaatatcgc atgttgttcc aaaaagactt
     5041 cttaatcgat ttaatcggtt accgtcgata tggtcataac gaaatggatg acccagcggt
     5101 tacgcaacca caagtgtaca aaaaaattaa aaaccaccct actgtaagag caatttacgc
     5161 agatcaatta caagctgctg gtgttctaaa tgcagatgag gttgaaacaa ttacacagtt
     5221 tatacaagag caattaaaat ccgattatgc acaagtacca ccagctgata cgagcgatgc
     5281 aacaattcac gttaaagtgc caaatgttgt tgcaaaaggt attcaaccaa tcgatactgg
     5341 tattgaactt gactcacttc gtgcaattaa cgaaggtcta ctatcttggc cagaaggatt
     5401 taacgtatat ccaaaagtga agaaaattct tgagcgccgt aaagatgctc ttgaagaaaa
     5461 cggtaaaatt gaatgggcac ttgctgaatc gttagcattc gcttctattt tacaagaagg
     5521 tacgccaatt cgtttaactg gtcaagattc acagcgtggt acattcgcac accgtcatat
     5581 cgtactgcac gatacagaaa caaatgaaac atattcaccg ttacatcgct taccaaacat
     5641 taatgcatcg ttctctgttc ataacagtcc gttatcagag gctgctgttg ttggttacga
     5701 atatggttat aacgtattcg ctccagaaac tcttgttatg tgggaagcgc aatatggtga
     5761 cttctcaaat actgcgcaag cattatttga tcaatatgtt tcagccggaa gagcaaaatg
     5821 gggtcaaaaa tctggtttag ttcttctatt accacacggt tatgaaggtc aaggaccaga
     5881 gcactctagt gcacgtccag agcgtttctt acagttagct gctgagaata actggacagt
     5941 tgcaaactta acgagcgcgg cacaatactt ccatatcctg cgtcgtcaag catctatctt
     6001 aggaacagaa gctgttcgac cattagtact gatgacaccg aagagcttat tacgtcaccc
     6061 acttacgctt tcaactgcta gtcagttaag cgaaggacgt ttccaacctg ctttagaaca
     6121 agaaaacctt ggcatgaaac caaataaagt aaaacgtctt gttttaagta caggtaaaat
     6181 ggcgattgac ttagcagcag aaatcgagtc tggtaaacac gagtacagct tagacgaagt
     6241 tcatgtcgtt cgtattgagc aattgtaccc attccctgct gagaaagttc aatctattat
     6301 taaacgcttt aaaaacttag aagaaatcat ttgggttcaa gaagaacctc gtaatatggg
     6361 cgcatggcat tacatggctc caattctgtt cgaacttgct ggagataaag tgaaaacagg
     6421 ttacattgga cgtcctgatc gctctagtcc atctggcggc gatccattcg ctcacaaagc
     6481 tgagcaagaa ctaattgttg cacatgcttt agatgtgaag tataacttcc gtcaagataa
     6541 acaagaaatt gaagtttaca gcaactaaaa agtaataatg aagatttcta gcttgttcct
     6601 tgggcagata ttctgcccaa ggccaggcta acaaatggag attaccgaag acaaaagaag
     6661 aaaaaacaca ccgttaggca aataagggga ggacatttaa aatgatcgaa attaaagtac
     6721 ctgagcttgc agaatctatt accgaaggaa ctatttcaca atggcttatc aacgtaggcg
     6781 acaaagttga gaaaggtggc agcgttgttg agcttgaaac tgataaagtc aatgtagaaa
     6841 tcattgcaga agattcaggt attgtatcga agttactagg cgaacctggg gatacagttg
     6901 aagttggcgc aactatcgca attttagatg ctaatggagc accagttgca gtaagtacac
     6961 ctgctccagc tgctgagcaa ccaaaacaag aaacagctga agcaccgaaa gctgcggctc
     7021 caaatgctga acaaactacg ggtctacaag gcttaccaaa tacgaaccgt cctatcgcat
     7081 caccagctgc tagaaaaatg gctcgtgaat taggaatcga cttaaacgac gtacgtagca
     7141 cagatccact tggacgcgtg agaccacatg atgtacaagc tcatgctgca gcaccaaaag
     7201 aagcaccagc tgctccaaag agcccagctc ctgctccagt tgcaaaaact gaattcgaaa
     7261 aaccagttga gcgcgtgaaa atgtcccgcc gccgtcaaac aattgcaaaa cgtcttgtag
     7321 aagttcaaca aacatctgca atgttaacaa catttaacga agttgatatg agtgcgatca
     7381 tggaattacg taaagaacgc aaagatgctt tcgagaaaaa acatgatgta cgtcttggct
     7441 tcatgtcatt cttcacaaaa gcagttgttg cagcattaaa acaattccca ttattaaatg
     7501 ctgaaattca aggtgacgag cttatcatca aaaaattcta tgatatcggt attgcagtag
     7561 cagctccaga tggattagtt gttccagttg tacgcgatgc taaccaatta aacttcgctg
     7621 aaatcgaaag tgaaattcgt aatttaggta tgaaggcacg cgataacaaa ctttcattaa
     7681 aagaactaca aggtggtaca tttacaatta caaacggtgg tgtgttcggt tctctaatgt
     7741 caacaccgat cctaaatagc ccacaagttg gtattttagg aatgcataaa atccaagtac
     7801 gcccagttgc aattgataac gagcgtatgg aaaaccgccc aatgatgtac attgctttat
     7861 cttacgatca ccgtattgtt gatggtaaag aagcagttag cttccttgtt gctgttaaag
     7921 atatgcttga agatccaaag tcattattat tagaaggttg atagattaaa atctattaaa
     7981 ggctgtagaa tgaatcattc tacagccttt ttttattgtg ttcatacggg acaaatttca
     8041 tgacataaag tattaatgta tgcctaaacg taaggaggat taaaatgaat aaccttccaa
     8101 ttcatgcaaa acttaaagta aataaggata ctttcttcct ccccgattca aacgggggtg
     8161 tctattttcg aaataacgcc agttcatttc gcatggacgg tgatggaatt tatgactgga
     8221 ttgaaaaatt aatgccaatg tttaacggta attattcttt agcagaaata actgagggtc
     8281 tccctctccc ctatcaaaat cgtgtatttg aaattggaga ggttttatat gaaaatggtt
     8341 tcgttcgcga tgcaaatcaa gatgcacctc atgaattaaa cagttcatta ctcgacagat
     8401 atgcttcaca aattgaattt ttagaagctg attctcattc aggtgcttta aaatttgaaa
     8461 cgtaccgcgg agcaaatgtc cttgtacttg gctccggaga tatgcttact tctttagttt
     8521 cttctttatt agaatctggt ttacctacat ttcattacct cgttacagat cgggatgaaa
     8581 caaactatga cagaatacat gagctaatag aacgtgcata tgaagttgat aacaatgtac
     8641 tccttcaaga aatcgatact acaattgacc gtcccttgca tgaagtattc gaaccttttg
     8701 attggatttt atatgtttct caaaacggag acattgacgg tttaaaaaca gttcacacta
     8761 tttgtagaga aacgaaaaag aatttcatac cagctatttg tttatcaaca ctcggtatag
     8821 ctggacctgt cgtaacagaa aatcgtgatg aatgctggga atccgcatgg catcggctac
     8881 atgaaacgac tttgcaaaat gaaaattcat cggattcctt ctcaccaatt acatctgcaa
     8941 tgttaacaaa tgtaatcgtt tttgaattgt ttaaacatgt cgcggatgat tcatatcgtg
     9001 aaaaagaatc acaattcttt ttattaaact atgaaacact tgaaggaacg tggcatcctt
     9061 ttataaaaca ccctcttgca gctgatgaaa gttttacaat tgatacgata gaaaatcttt
     9121 ctgaaaaact tgagcatcgg tccaaccaac atacttcaac tgatgtattc cgattttttg
     9181 actcattaac ttctaaagaa gccggtatat tccatgtatg ggatgaacaa gattcatatc
     9241 aattaccgtt atcacagtgc tatattcaag tagccactcc actatcagat ggcccagctc
     9301 cccttctgcc tcttatgact cgcagtggat tgactcataa tgaagcacgc cgagaagctg
     9361 gtttaacagg aattgaaaca tatgtagcag aaatcattca ccgccttatt cctgaacata
     9421 atgatatcgg tatcggtgct ggagaaacga tgacagaagg attttaccgg gcactacaac
     9481 aacatttaaa taataaattg tatgagcggc agtcacatat gctagaagaa cttacaacga
     9541 ttgatttaac tgatattcac gataaacatt gtagatttta ttacgatgcc ctcgctacaa
     9601 ttcatgaaac acctaaaatc gcaatgagtg aagagattct cagttttcca gtcgtttggg
     9661 ttggtataaa tgatagatgg tacggtgcat ctaatattaa tatgacgtta gcgttacgaa
     9721 acgcactaca actatcactc tttcacattc aaaatgaaga aattccttac agagctaata
     9781 ttttgtatga ctcatctatt attttatatg acactgattc tcttagagtg gaaatacaac
     9841 cagaagaaga aattccaagc gtacaatctt tacaactcgc cttacaacat ttagaagaac
     9901 ataattttta tcctttcgtg tttgatttag caatcgaacc ctttttgaaa gaaaacttag
     9961 acggtgtgta tggggtatta attgcaaagg aggacggttt atgattcaaa atatattgct
    10021 tataggagat ggccttcttg cagactatgt acatgatcaa ttatgcaaac aatattccat
    10081 cattcgtcag cataccctta cagaagaact tcctgaaaat attcatcttg ctctcgtatt
    10141 acatgatgga tctccttcta ctattcatca tgatgctgag ctaatttttc ggtcaaatca
    10201 tattccgtgg ctacgtggtt ttacttcatt tggcgaaggt attatcggtc cttacattca
    10261 tcctcttacg cccggatgtt cccattgttc tgatggacgc cgttttatcg ctggctttga
    10321 tcaaaaagaa atgtgggaac tacagcggaa atatgccttt aaagcagata atgtaacgag
    10381 gcgtgatgta cgtgccaccc aaaatggaat gttacaaatg tgccatctta tttgcgcaga
    10441 aacagaaaaa atattaactc ataaccattc ttctttagaa aatgaactta ttttactcaa
    10501 cttacaaaca ttacaatgta cgcggcattc ttttcttcca gatcctctct gtcctgtatg
    10561 tagtaattta cctgatgata ctgcggatgc ggcggaagtt tctttacaac cgagtttaaa
    10621 agtaagcacc gaaacgtatc gctgccgttc cattcatgaa ttaaacacat ttttaacgag
    10681 agactattta gattatcggg tcggtatgtt gaacggcaaa atgcagcatt ctttattacc
    10741 attcgctgac gtcattataa acatgccatt aatgttcgga aatgaaggtg ttgcaggccg
    10801 aactcattca tttgtagtga gtgaagcaac tgctatttta gaaggtttag aacgatattg
    10861 cggtatgtcg cctcgcggga agaagacaaa tgtgcatggt agttttcatg atttagagga
    10921 acatgcacta aatcccctta cactcggtgt acatacaaat gaacattaca atcgtgataa
    10981 ttttccattc aagccgtttg atcctgatta tgagcaaaac tgggtatggg gatattctct
    11041 atcacaagac agaccgcttt tagttcctga atcaattgct tattatagcc tcggtcatcg
    11101 agatgctttc gtgtatgaaa catcaaatgg atgtgcaatt ggcggtagtt tagaagaagc
    11161 gatttttcac ggtattttag aaattgtaga gcgtgatgcc ttcttactca cttggtatgc
    11221 cgaattacct cttccccgcc ttgatctgag ttcagcaaat gatacagaat tacaattaat
    11281 gattcagcgg ttacgtacga ttaccggata tgaattacac gcttttaatg cgacgatgga
    11341 acacggcatc ccgagcttat gggtaattgc aaaaaataca cgtgaaaatg gaatgaacgt
    11401 tgtttgtgcg ggaggcgctc atttagatcc tattcgagct ttaaaaagtg ccattcaaga
    11461 aatagcaggc atgttactta taacagacga tgagctcgag cacaaaagag aatactacga
    11521 aaagtgctta caagatcctt attttgttaa taaaatggaa gaccatagta tgctgtatgg
    11581 attgaaagaa acggaagaac gtcttcactt ccttttacga gaagatgcac cggtgcaaac
    11641 gttccaagaa atgaatgtat cacaatcatt tgatatggat ttaacttccg atctccacca
    11701 acttttaaat cgtttgcatc aatctgacct tgaagtaatc gttgtagatc aaactgttcc
    11761 ccttatagaa aagaacggac tacactgtgt aaaagtcatt attccaggca tgctaccgat
    11821 gacgttcggt caccatctca ctcgggttac aggactggac cgggtatata ctgtaccaat
    11881 gacacttgga tatacagacg aacctttaac gaatgaaaga ttaaatccac atccacatcc
    11941 gtttccatag taaaggaggg atttcatgca gctagatact tttttacatc atctccattt
    12001 ctctattgat gaaattatgc cgaatcatga ggtggactgg aaagacgcac cgcttcctta
    12061 taaattatat cgaaatgtac ctaccatccc gctctcctta gaaatcccgt tatctttatc
    12121 gaactcttct actacaccta ctctaaatga gattggtcac tacctttggt attcatttgg
    12181 tgtaacacaa ttatgtcagc taaatagcga gagaaatgta ttacgcagat ccattccttc
    12241 aggcggtgct ttatatccga atgaattgta tatctattta aagattgacg attatccaga
    12301 cggcatttac cattatgacg ccgcgcatca ccgacttatt ttacttcgcg aaggaaattt
    12361 cgattcttat ttagcagacg cactcggtaa tcgctgtaat atacatgatt gtttcggtgc
    12421 cgcattcgta tccactatgt tttggaaaaa cttctttaaa tacaataact tttcatatcg
    12481 ccttcaagga ttagatagcg gggttctcat tggacaatta ctagaatgtg caaaacagtt
    12541 cggttatacg aacggcgtat actttcaatt tctagaccgt gcactgaacc atttactcgg
    12601 attgtcagaa ggtgaagaaa gtgtgtatgc cgttattcct ttaagtacag agccagaaac
    12661 taattggttt cacaatgatt accgtgaaaa taaaacagtt acttctcatg agttgttgca
    12721 acaaattccg ccgttagcac atgaacattt cgttcgctca aaacatgtaa atgaacatcc
    12781 gatgataaca aaaataaatg aagcttctat gattgaatcg acagaacact tccaaacact
    12841 acatcatgaa gagcactatc aacataatac gtacgctgta cagctaccga aagtagaacg
    12901 gttatcgtat gatttcctac aactttgtaa aaaacgatat tctcctgatg cggactttat
    12961 tttaacgaaa tgggatgcag ctgagctcgc tactttacta caagaagcga gcctctcctt
    13021 cccctattac aacgaccttg atggtaagta tgtaaatgaa aatgcgcgcg tctccttata
    13081 tggatgtttt tataacgtga aaaatattaa aaacggggct tacgcttata acagtaaaac
    13141 acattccata caaccaattc gatatggaga ccttcgctac ccacttcagt ctagtatgac
    13201 gatggataac gtaaaccttt ttcaagtacc actttgctta catgtagtcg gaaagaaaga
    13261 ttattataca aatgcattag gctatagagg gtaccgtatt catcaaatgg aagcaggtat
    13321 actcgttcat aaactcgttt ttgcatcgac cgcgatgggg atgggcgggc atcctttact
    13381 tagttttgat acaaattcat gtgatcaatt gtacggaata gatgctggaa atgaaacatc
    13441 tcttattcaa gttccagttg gggcatatcg ggcgcggaat tggttaaaag gggctttgca
    13501 tagttaaaag cacgccgatg aacggcgtgc ttttttacta gattaactta aaaatactct
    13561 taatttgtct agcaaataac caatttttcg taccgtagtt atcatttaaa ctatctaaat
    13621 taatagattg tccgttagca aactttaatt ctaacgttgt atttttgtca tttgttttta
    13681 aattactatt tgtaatatca tcatacttta atttttcaat ctcaatatat tcgtcttttt
    13741 cttgtccgat cacgacatgg tcttggaaga agaaaaatac ttctactttt ttaccgaaac
    13801 aaaatacatt tttcgtataa attaatgtcg cgttatcaag tccgacacat acttctttca
    13861 tttcttccac aacgtgtcca aagtcttctt catgtcttgt atttgattca acaatccatt
    13921 cttcgattgt tttcatatta attgccatac tgcgccccct ggttcgttca ttgcttcgtt
    13981 taaaaaataa atactatatg aaaatataag cgattagtaa tatgttttca agggggaacg
    14041 gtatattcaa aataaagtga aactttaatc aataggggtc ttcatcccca ctgattatta
    14101 gttgaaccaa tcgggctttt atgggcagtt gatcccccca cctaacttct ttgctttcgc
    14161 tggattttga ggtgtgggtc ttactgtccg caaatagcgg gataaagtta aatttcaaag
    14221 taatataaaa ggaaaaccaa tttcattaaa ttttaaacgt ttgaacgaga cattcttcat
    14281 catcaattaa ctgctctctc tcatcaaatt caatgttcag ttttttatat actttcttcc
    14341 aaaacgacac tgctggtaca ttttttagaa gttcgataac gaaatattgt cctcttttct
    14401 cttctagtaa attctcaaca gcttgtttac cgattccttt tcctttatat tgattcaata
    14461 tgaaaatatc attaatacca aaatcatttt ccttcttcaa aaacggacgt tccagtagta
    14521 ataagaatcc tacaatacta tgatcaactt ttataaaata cggcgtgatt ccgtcatttt
    14581 tccaaaacat atgcaaatct tcgtattcaa aaaatccgtt cgctccgata gttatattca
    14641 tagtgaactt agaaaggtca tgaagatata aagcgtacaa attacgtaat atttcttttt
    14701 ctgattcttg aaccttttga agtgctacaa tcataaaaaa actccccttc ctcatatgta
    14761 actatttccc gatcctcttc attcgacaaa aatgataatt cccctttaac aaaaaaatag
    14821 cactttaaaa agtgctattc tgctctcctt gccgcttgct gaattgggtc ccacacgctg
    14881 ttatatggtg gtgcataact taaatcgaca tcttctaaat catgaatgct cattttattg
    14941 aaaagtgcca tcgcgatcac atcaatacgt ttatctacgc cttcttctcc aattacttgc
    15001 ccgcccaata attgtttcgt atcggagcga tatagtaatt tcaagtaaag tggttttgca
    15061 tttggataat agcccgccat atttgtagaa tctactttga ccgttttata cggaatgtgt
    15121 agcccttttg cttctttttc atttaaccct gttcttgcga gtgtcaaatc cataaattta
    15181 ataatgcctg tgcctaacgt acctttaaaa gctcttcgtt tatcaagcat attcagtcca
    15241 gcaagtcgcc cttgcttatt ggcagtcgtt ccgagcggga tatgatcatg aacttccttt
    15301 ataacgtggt aatgtgttgc gcaatcaccg gctgcatata cgtcttgcac atttgtttgc
    15361 atatatgcat ttatttcgat tgctccttta tgattcttac gtatatttgt cccttcaaga
    15421 aaatcagtat ttggcttcac tccaaccgac actaaaacaa gatctgcttt atacgtacct
    15481 ttatccgttt cgattgcttc tactcgttca tttcctttaa atgcttttac attttcattc
    15541 gttaaaattt caatattgtg tttatctgct tctttatgta tatattcagc catatctgca
    15601 tcataaatcg taccgatatg atcatttcgc tcaatcattc ttactttctt accaagttcg
    15661 acgaatgttt ctgccatctc cagtccaatc gcaccgccgc caataatggt tacatcttca
    15721 actttattcg tttctaacgt ttttaatatg cgctcagcat ccggaattgt ttttaaaaga
    15781 tgaacgcctt gtaattccct tccttcccat tctggcataa caggacgtac tccagtcgca
    15841 attaataatc gatcatatgg aaattcaaag acatccttcg tcttcgtatg ctctgcgtac
    15901 accattttct tttccgtatc tactttcgtt acttcatgac gcactttcgc atcaattcca
    15961 tatttctcac gaaacgtctt tacgttgcgc gcgattaact tttcagttga agcgatagca
    16021 ccactaatga catacggtaa tccacactga gcgtatgaat aaatttcacc tttttctaaa
    16081 gttacaacat ttgcattttc atcgtttcta acaatttgca tagctgcact cataccagct
    16141 gcatctccgc caataatgac atagttcact ttaccactcc ttctttttta catactcttt
    16201 acgttttcca tattttatag aaataacacc tacttccatt gtaaagaaag agaatttcat
    16261 cttcaaattt ggtgcacaaa cttatgtatg aataggtaac tgtcgtgtct tataaacaac
    16321 atgtttaata tgctataaca gtaaccaatt gaaagtaggt gaaatataca tgtgcgctgg
    16381 tcttctcgct caatttccag aggaaccgaa agaaccaaaa cccgccttgt cgcttgatca
    16441 agaattttct attaacgcaa ccatttatag tgctcgtgct tggttatcta atgatgaaac
    16501 ttttccacaa acgatttgga aaggctctca ctttgcttca gcatcacacg ctggcaagtc
    16561 catcttacca atcggtactg taaaaatttt gaacttatct gatgatacaa taacagttac
    16621 tgcatcatca gaatcagatg atactctcaa aatagtcgta ccccctcatt ctgaaggtgt
    16681 tttaacatct aacgcattat ctgacgtgca agcaagtaca tcaggaggag caagtaaagt
    16741 cacattcctc tttcatatct ttttctcaag ggatcctggt tcagataaaa aaccataaaa
    16801 aaggtacagt tatgcactgt accttttttc atgtgttcta ttctcttgat ttaatcagtt
    16861 caatattata agtttcgata tctgttaacg ttcctgtaaa ataagggttt tctctatacc
    16921 aagactgttt tgcaaaatac gcttgcatat ctttcgtttg aaaaatatgt ccatgccttg
    16981 catatatttc atttctagca attttcaact gttctttcga taaataggtt aaatctgtgc
    17041 ttgttaattt tcgaatatca ctatcaggaa agatgaaacc attatataca tacccagtcg
    17101 taggtggcgg ggtaatatta taaacaactg ttttttctgt acttttggtt tggaatggaa
    17161 gattataaga cgaaagtgcc gttaccgtct ctacttttgt cgtttcccgt ccattttctc
    17221 catttcgttc taaataaatc ttcgcgcttc catcagtcgc tacaggcccc catgtaattt
    17281 cttctcctgc cagcgctgta actggttttt gatttacgta caatgttgca ccaggcgcgt
    17341 tcgtttgaac tgtaatatat tgaccttgca acgttaaatc tatcgttacg ttattttggc
    17401 tttgtttcat aagtacaacc ttttcctcac gagatagttt tacatagtca tttttatatt
    17461 ctgattgaaa cacttgattt cctggaaggt atggcccata ttgcttctca aactttttgt
    17521 catctgtctt atcaatttct tttccgttca tttttaacga tacgcctttt tcatttgtaa
    17581 gcaaagttgt atagtacgtc ttcaccttca atttataccg atcaaatata aagaaatact
    17641 ttccgtcttt cgttaatgaa aaatcagctc tttctattcc gtcccgttgt ttttcacctt
    17701 gtctcaaata ttcttttaat tcattcacgt aagatggatt ttcttttata tatgaaaata
    17761 aaggcgttaa actctctttc gttatcataa ccgatggatc atctgctgta acgatctcag
    17821 ctaatttctc tccgtccctc tcttgtaaaa tcgtaatcat ccggtctact tgtgccacct
    17881 gcgtataata cgacaatccg tacaaataca atccaataat cgctataaca aatagtgcta
    17941 acagtgtaat gccaactttt gtaccaccgc tcatgttctt ctttactaca ggacttcccc
    18001 tcttcattcc gcagttttga caaaattgca caccatcttc aaactgaact ccgcactttg
    18061 tacatacatt cattcagtca accacctttt cattagaagc cagttattcc ctgtgttaag
    18121 gcttgaatta tcgtgctaat gtaagaccaa agtacaatga acgttgcaat tccaattaaa
    18181 acatttgcaa taataagtgt gtaaacgaga tctaatccgc cattgtctag ttttaatacg
    18241 gctacagtta tactaatccc tatataagtt gcaactaccg ataataatat cggtaagaaa
    18301 aagattaata aaaaactaaa aagaaaagaa aggactaata tcaaaatagc cggcgtcgct
    18361 atcgttcccc atataccaaa tacttcaaga aatgaaaaag atgatttcat catcttacca
    18421 cttacaaaaa taataaatcc gacaaataaa gttaaaatta ataaaaagaa aaagaccgtt
    18481 atagattctc caaaaaacgt gggagtagat atatctggtg caaatgttct cgtaactgct
    18541 gatgctgcac tcatcattct ataaaaaata catgctccta aaaaacaaac aagaacaaga
    18601 cttacaattc catttcgcac ttcaatagtg ccgcttttca taatcgctgt cggtgcttgt
    18661 aatgcatgtt taaaaaattg aaaatagccg ctcgcaaacc gcttcgcttg ttctaccgtt
    18721 tcatttggac gcgtttcctt ttcttgtgcc gcgcgcgctt gttcctgccc ttcttctttg
    18781 ccactacttg ccactacttc ttccgttaac gaatgtccac aattcccgca aaactttgcc
    18841 tctactgcat gttctgtatg acatgacgga catttcattc tctcatccct ccttaagcat
    18901 ataccttata gggtgttaca aattcaatat atgactttgt acataaaaca tgactacaag
    18961 aaaaagatta tgaaatcctt cttccgaaag aaaatatatg tgctagcaat cttgaaaaat
    19021 aatgctatta tgaaacagaa caaataacat ttttaacaga ttggatgaaa gataatggaa
    19081 ttggtaaact caatttttca aatactcctt acaagcataa tccaattatt ttccttaatt
    19141 ggcgttatca ttgtaattgg atttctatta ggttatttag aatcactaac acggatgtat
    19201 tggtcgagag cttttggaag aaaaggattc ctattaacag cttggatcgg tgttccgatt
    19261 cacgaacttg gacatgccat tatgtgcgta ctgttccgtc ataaaattgt ggcgactcag
    19321 ttcttcccaa cagatacaag tcaaggggct ttaggttata tacaacatca atacaatcaa
    19381 aaaagtgtgt atcaacgaat tgggaatttc tttatcggca ttgggcctat tatttctggt
    19441 attactgcat taatcctttt aatgcgctat ttcgtaccag aatcatattt tttatttaat
    19501 acaactctcg aaaaaacgat tgcttctact tctattaatg tagaaatgat tcaaaacatg
    19561 ctcttgtcga cgtttgtatt attgaaaagc ttatttacaa tcggcaattt attgaatcct
    19621 tccttttggt tatttttatt tatcgccatt tgcatttccg cacatatcgc tttaagtaaa
    19681 ccagacatta aaggatcaat agacggagtt atcgtcatgt ttatcgtatt atttttattc
    19741 aatataatag ccggactttt tcagtacgac agtaatcagc taattggaca ggttataaaa
    19801 tataatatgt atctcattgc gttttctagt gtagcactgc ttttctcttg tatttctaca
    19861 ctcgttagtt tttcgtttta taaaataaga agagggcgtt ctttttgaac gccctcttct
    19921 tattaattat tccccttata atcacaatgc tcaaccggaa cacgagcatg cccctcttca
    19981 tcggtacacc atgactgtga ttggaaggca agaaagatac caatccattc ttcttccttt
    20041 tcaaagtgaa tgagtattcc tccgtcttgc catataccat tatctccttt ccatttctct
    20101 acattccctt gattcatgtg aatatcatgt ataccgtttc ctggtttgaa atgaaaatag
    20161 gaatctggtg tattttcttc tggtccccat ctttcgccaa acgcgtaaat aattgctttt
    20221 tcttctatcg ctcgctttat ataacgttct attttttcgt ttaaatcatt atctgctcct
    20281 gctttttcgg gaggcaaagg aatcatttgt tttgagtcaa atagatttcc tcttacataa
    20341 tctaaagcta ctttcggttc attatttttt acttccgtaa aaccaaatgg taatgtcggt
    20401 aaaatatgaa tcgcctctga cctaatattg ttactcgcaa aatataaaac ttctgacgga
    20461 taactttgcg actttacgtt aatagcaata cgataatcta ctccagtctc gccctgtaaa
    20521 tgaacttgat aatgaggtgt tttccctttt ccaatctttg attgtataac tgtacctttt
    20581 aacacaccgt agttttttag gggcatacat ttcatctcct attcatttag tagaagctat
    20641 tcatatttaa atcattatcc actcataaaa aaaatcctcc tatgttagaa ggatttttaa
    20701 tttctcaaca tataccaaac aataacctct accactacaa gcaaaaccgc accaaagatc
    20761 attaacgtcg tcttctttaa cagttcattt tcacggtaag ggatattaca taagtaagca
    20821 cctagtgtaa tccgtgatgg acaagcgatt gtcgctactg atgatgcggt gttttgcagt
    20881 gttgtgacat attgccacgg gagtgctacg ttttgtgcgg tttgcatttg tagttttata
    20941 aacattgcat ttgatcctgc attactacct gttaaaaatc caccaatagc gccaataaac
    21001 ggagcaacga aaacgaaaaa cgttccaaat gtgtccccag ctgtttttgc tagtaatgaa
    21061 tgcatgccag atgcgcccat tagttctgaa atagcaataa acattgtcgt cgtaatcgca
    21121 aaaggaatcc attgtttgat cgtttgcgag agtgattgtt taataatatt agacgggatg
    21181 cggaagaaaa taatagtaaa taagcaagtc ataccgagcc aaaatcctgg tgaatatagt
    21241 aactctagtt tgtaagagta tgatttcaaa tcaagaaccg catatgatct gaacaaatca
    21301 tgtaatgctg gaacgaggcg agaaagtaaa atacaaactg ttagaaatat ataagggcta
    21361 ataattttta taatggatac ttctctctcc gttgcagccg catgttctgt tataagattt
    21421 tgcccacttt ttccttttaa tttaatgata agaaagccaa atgtaatcgt aacgatagaa
    21481 cttaatatcc cggctagttc aacacttacg tacgcattag aaagatagat tccgagagaa
    21541 aataatagaa agaatcctac tccttctttc cacttttcta taaccgcttg ccagccgcca
    21601 acaacgtgta aagaaagaat aacaaagtaa gcaaacatcg gaatacttaa tagcgctgta
    21661 tttgtaccaa gtgttgtaag aggcatattt attagctgcg aaccgataat tgtaccagtt
    21721 gccattgcgc cccatgaact agctagtaag ccgataaatg agagcagtac agcttgaaat
    21781 ggcttatatc ctagtgaaag aaaaataggt gctgcaacca tgaagccgat accgaatcca
    21841 cttactgatt caataagcgg gcaaatgcca aaacacataa gcagcatttg taataagcga
    21901 tcctgagtaa cttcttctag aaaacgtgct acttgatcga tgtaccccat tttgttcatg
    21961 aggtgaaata aaaaaatccc gaaaaataaa acgtacccaa caataaaaca aattaaccat
    22021 cctttaatcg ttgcgtgtac agtttcactt atccctaatt gaaacgttgg cgagagtaaa
    22081 acgattccaa cagacacagc ataagaaatt aacgaagacc ttaatgacgt ttgtttaaat
    22141 aaaaataaac aaatgaaaat catcataatt gggataagtg ccaacaatat ggccatgtta
    22201 tcatctcatt tcgtttaaaa tacaattttt aactattata taacagatgt tataattttc
    22261 aactgttttt acaacagatt caaaaaagga gccaaatggc tcctttcact cccattttct
    22321 tttatcctga aaaacgctct gctgcctaat tattttgtct aacacaacaa acacaatata
    22381 agcacatatt acttgcaata caacatttcc aaatttcatt aattcaaatg aatgaatcca
    22441 gcgaaataat tcgtttaata atacaatcga aacgatacta aatagttcta tactaatcga
    22501 aaatagacat atttctaaaa tagactgttc ttgaatgcga tttaaattgg aaaagatgaa
    22561 tacataccct aaaaatagag ccattaactc tatttttgtc atgctaatga gccaagcgta
    22621 tagcggtaca gttaaaaata gatatagtag tttacgtctt agcatgcctt ctcaccctat
    22681 aaattatatg tattttctgt atattttaac atttattacg caaaacaaaa agaagagact
    22741 acgcctcttc tttttgtttt gttgcatata ttaattcaca tatttcttct tgcttttcat
    22801 tttctaaaag ctcaatgatc ttacttccaa cgacaactcc gtcgcatatt gtaaccattt
    22861 cttctacatg ttcttttgtt gagatgccaa atccagcgac tactggtaag ttgacgtgtg
    22921 attttacttt ttctaagtaa ctatgaatct cctctttaaa gttttgacgt actcccgtta
    22981 cgcccgctac tgtaacagca taaacgaacc cttctgattc actcgtaatt ttttcaattc
    23041 tttcaatagg actcgttacg gtaacgagtg gaatgagcgc aatgtttgcc tctcgaagta
    23101 acggcgcaat aatattttgt tcttcatacg gtaagtctgg aacgatgatg ccgtctacac
    23161 ctgcttctat acagttctca atgaatctct cttttccgaa tgcaagtacc ggatttaaat
    23221 atgtcataag aacaaaaggc atttgtactt ctttccttac ctctgctaac gcttgaaaaa
    23281 tgccttttaa tgttacgccg ctatctagcg ctcgctttcc tgctctttga atcgttgggc
    23341 cgtccgcgac tggatctgaa aacggaatac caatttcaac gatgcttgct ccagcttcat
    23401 ctagaaaacg aattctttct tttaattttt caaggccgcc atctccgccc attacgtacg
    23461 gaataaatgc tttcttgcca ttttcaaacg ctgctttaat tttttct
//
