LOCUS       NZ_NTWJ01000043        19912 bp    DNA     linear   CON 01-APR-2024
DEFINITION  Bacillus thuringiensis strain AFS009835
            AFS009835_104_C9_Contig43_140523, whole genome shotgun sequence.
ACCESSION   NZ_NTWJ01000043
VERSION     NZ_NTWJ01000043.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus thuringiensis
  ORGANISM  Bacillus thuringiensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 43663)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Large-scale bioinformatics analysis of Bacillus genomes uncovers
            conserved roles of natural products in bacterial physiology
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 43663)
  AUTHORS   Bleich,R.M., Kirk,G.J., Santa Maria,K.C., Allen,S.E., Farag,S.,
            Shank,E.A. and Bowers,A.
  CONSRTM   Agbiome Team Llc
  TITLE     Direct Submission
  JOURNAL   Submitted (07-SEP-2017) Chemical Biology and Medicinal Chemistry,
            UNC Chapel Hill, 125 Mason Farm Rd., Chapel Hill, NC 17599, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Assembly Cell v. 4.2.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 61.85x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_002562205.1-RS_2024_04_01
            Annotation Date                   :: 04/01/2024 01:49:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,978
            CDSs (total)                      :: 5,906
            Genes (coding)                    :: 5,721
            CDSs (with protein)               :: 5,721
            Genes (RNA)                       :: 72
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 185
            CDSs (without protein)            :: 185
            Pseudo Genes (ambiguous residues) :: 0 of 185
            Pseudo Genes (frameshifted)       :: 82 of 185
            Pseudo Genes (incomplete)         :: 109 of 185
            Pseudo Genes (internal stop)      :: 57 of 185
            Pseudo Genes (multiple problems)  :: 52 of 185
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:13:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 23751
            Orig. end                         :: 43663
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NTWJ01000043.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..19912
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..19912
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..19912
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:19611](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19611
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(214..1935)
                     /locus_tag="CN427_RS29295"
                     /old_locus_tag="CN427_29300"
     CDS             complement(214..1935)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016084292.1"
                     /locus_tag="CN427_RS29295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29300"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_097946608.1"
                     /transl_table=11
                     /translation="MEKDKDVSLKALWKITTPPKVTLFLGVIFGLINSVCSLIIPLILK
                     EQIEQLSKGFSYELLFLVLVLLIVEIISMALSLYLLSLVGQRVVLNLRKMIWRKVLNLK
                     VDFYSKNQPGEIISRVTNDTTVTMNLLSSEIADLLSSGLSMIGAVVILFLLDVPMTLTL
                     LSAVPVTLFIVIPISKKIYKISYEQQEKMSEFTALLSQVLGEIRLIKSYGTEDFEFERG
                     KKKIEELYVNGIKRAKIESILIPLMTVSITLIIVVVVGFGSYRVSEGYLSSGELLAFIL
                     YLFQIVGPVGVMSRFITNVQSAKGSTERIFNILDEKDEKNKDDFLEEPSFGTLEFKDIG
                     FAYDEKSIFENINLKIMPNTVTALVGPSGVGKTTLFYLLERFYDPLKGEILLDGKSHLN
                     IDLDKWRSMFSYVSQDCPILVGTIRENITYGIQREVSEDEIIKASILANCHEFITSFSD
                     GYNTVLGERGINLSGGQKQRISIARAFLRDTPFLLLDEATANLDTNSENMIKHALDNLI
                     YKKTTIVIAHRISTIQNADQIVVLDQGEVSGFGTHDQLIKSNKLYQLLSNQQKMTS"
     gene            complement(2850..3050)
                     /locus_tag="CN427_RS29300"
                     /old_locus_tag="CN427_29305"
     CDS             complement(2850..3050)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN427_RS29300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CN427_29305"
                     /product="hypothetical protein"
                     /protein_id="WP_097946610.1"
                     /transl_table=11
                     /translation="MLLSDNDIKRELIKGENITIYPLNIKGSSINLTASKYAWKVSDRE
                     TAIIEDKIAIPPNEAVCIYTQ"
     CDS_motif       complement(2937..3050)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLLSDNDIKRELIKGENITIYPLNIKGSSINLTASKYA"
                     /locus_tag="CN427_RS29300_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2850..2936)
                     /prepeptide="core"
                     /locus_tag="CN427_RS29300_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.90"
                     /molecular_weight="3149.6"
                     /monoisotopic_mass="3147.6"
                     /core_sequence="WKVSDRETAIIEDKIAIPPNEAVCIYTQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLLSDNDIKRELIKGENITIYPLNIKGSSINLTASKYA"
                     /leader_location="[2936:3050](-)"
                     /alternative_weights="3167.6"
                     /alternative_weights="3185.6"
     gene            complement(3458..4099)
                     /locus_tag="CN427_RS29305"
                     /old_locus_tag="CN427_29310"
     CDS             complement(3458..4099)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016084082.1"
                     /locus_tag="CN427_RS29305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29310"
                     /product="DUF3967 domain-containing protein"
                     /protein_id="WP_141534661.1"
                     /transl_table=11
                     /translation="MALCQKRRLYTSNEVYSHLGISGGTLRKYSDILEREGYDVRKNSR
                     GRREYTGFDVVLIEQLVELSKQNGMTLEKAAKMIAKQFGIDNKKEESQGEDLVPYQMQY
                     QFQQQYSAMIEEINKVQQANLLEMEKRLGNRIDQRNKLIEEDVKERNKLIVEDMKDRKE
                     REEKIEKRLELRDDNLMKMVREIQDAKRTIVSAQEEIAAAKRKSWWKFWE"
     misc_feature    4569..4582
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 25.44"
                     /tool="antismash"
     gene            4939..5169
                     /locus_tag="CN427_RS29315"
                     /old_locus_tag="CN427_29315"
     CDS             4939..5169
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002015952.1"
                     /locus_tag="CN427_RS29315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29315"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_097946612.1"
                     /transl_table=11
                     /translation="MIDGKLQNQLYIFRAKKKWSQKELAEKLGVSRQTIISLESNRYSP
                     SLVLAFKIATLFESDINEIFKYEVKGESEIQ"
     gene            5166..5456
                     /locus_tag="CN427_RS29320"
                     /old_locus_tag="CN427_29320"
     CDS             5166..5456
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CN427_RS29320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CN427_29320"
                     /product="hypothetical protein"
                     /protein_id="WP_097946613.1"
                     /transl_table=11
                     /translation="MIDNILTVVMFIFTIPMVYIMMFSSKEKDERGKQIINTSFHNAYF
                     ILLLGIFLVVISSKLAIFDMDFQTFGNLIVLAILISLIVAGMNIFINNRRM"
     gene            5528..6463
                     /locus_tag="CN427_RS29325"
                     /old_locus_tag="CN427_29325"
     CDS             5528..6463
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015383183.1"
                     /locus_tag="CN427_RS29325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29325"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_255285325.1"
                     /transl_table=11
                     /translation="MGIPIVQLKNVNKVLGNKTIIEDMNFEAYEGEVFGFLGPNGAGKT
                     TTIRMIVGLANPTRGDILIDGNSIIHKRKLAIKKVGAIVENPELYKFMTGYQNLKYFGR
                     IYGNVTKEKIDEIVELVDLTASIHDKVKTYSLGMRQRLGIAQALLHDPKVLILDEPTNG
                     LDPAGIREIREYLQYLAHEKKMCIIVSSHLLTEMELMCDRIIIIQNGKVVDTQSVRENR
                     KENEVLFEVKHPQQAREDILAVYSELDIECLDNLIKVCIKKEEIPLIINLLSKNNHQVY
                     GIKETAISLEERFLEITGKGERKHVSTYSK"
     gene            6441..7382
                     /locus_tag="CN427_RS29330"
                     /old_locus_tag="CN427_29330"
     CDS             6441..7382
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024091.4"
                     /locus_tag="CN427_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29330"
                     /product="ABC transporter permease"
                     /protein_id="WP_098399352.1"
                     /transl_table=11
                     /translation="MLVLIQNELIKILRRPGTYIMAGMIILLVIGAGVLTKYNVSKNVY
                     GDDWKVVLESENKNLTEKSKELNKGTLAYEKMQQTIAENQYRISNDLKPNSSVNTWTFV
                     KAAQAIISVVGLCTIVIAASIVSSEFSRGTIKLIMIRPSSRWEVLLAKYLSVIIFGFVM
                     LFLLFALAFLFGLCLFGISGENIHLVFQQGKVIQENMVGYLIKSYLLSSVDLLLMSTMA
                     FMISTVFRNNSLALGISLFSYLSGDMVTRLIAQKFDGAKYILFANTNLTMYTDGDVLVK
                     GMTPTFSITILSLYLVFFLSVSFVSFSKRDIL"
     gene            complement(7609..9000)
                     /locus_tag="CN427_RS29335"
                     /old_locus_tag="CN427_29335"
     CDS             complement(7609..9000)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002013845.1"
                     /locus_tag="CN427_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29335"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_097946619.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.9e-47, bitscore:
                     152.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIFSFIALLALFVVLTPFHNTYAEETKDYYTILVKDEKETQET
                     IKKISAHNTQIVYTVPEVGLVQVRSTESEIKNISKIDTIDTYNKSLKLTDSHEEINKSI
                     NVRTLPVLWESQWDMQKVTNNGESYKVFSGSKNVTVGIVDSGLDINHPDLKNNIVPGSK
                     NLVPLGGYKGGEPQETGDVNQLTDFRGHGTHTAGLVAANGNIKGVAPDVGIKSYRVFGS
                     SSGESAWVIKGIVEAAKDDVDVINLSLGSYLINGTTFSANGKSKKDIAEIKAYKKAINF
                     ARKQGSIVVAAAGNDSLNMRDKKQVAEFYNKKYEKDGITFKGEVLDAPADLPNVVTVSS
                     IGPSNELSLFSNYGAHFVDIAAPGGDTRLLDTYGKDAWVNDKWFAKESILSTSPMGGYF
                     YSSGVSTAAPKVSGALALIIDKYHFKDQPKKATNFLYKYGVNNEIKNKDHFGNGILDVY
                     KAVTH"
     misc_feature    9337..9354
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.94"
                     /tool="antismash"
     misc_feature    complement(9453..9467)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.71"
                     /tool="antismash"
     misc_feature    complement(9489..9504)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.11"
                     /tool="antismash"
     gene            9498..9692
                     /locus_tag="CN427_RS29340"
                     /old_locus_tag="CN427_29340"
     CDS             9498..9692
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="CN427_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29340"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_097946621.1"
                     /transl_table=11
                     /translation="MVEKEKMSKVIGVVDEHELKMLSGAAEVETRSSLPCAGLTVAVGT
                     WVFQTSEKTCPTLACSKAC"
     CDS_motif       9498..9572
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVEKEKMSKVIGVVDEHELKMLSGA"
                     /locus_tag="CN427_RS29340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9573..9692
                     /prepeptide="core"
                     /locus_tag="CN427_RS29340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.50"
                     /molecular_weight="3866.4"
                     /monoisotopic_mass="3863.9"
                     /core_sequence="AEVETRSSLPCAGLTVAVGTWVFQTSEKTCPTLACSKAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVEKEKMSKVIGVVDEHELKMLSGA"
                     /leader_location="[9497:9572](+)"
                     /alternative_weights="3884.4"
                     /alternative_weights="3902.5"
                     /alternative_weights="3920.5"
                     /alternative_weights="3938.5"
                     /alternative_weights="3956.5"
                     /alternative_weights="3974.5"
     gene            9778..9951
                     /locus_tag="CN427_RS31525"
                     /old_locus_tag="CN427_29345"
     CDS             9778..9951
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="CN427_RS31525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29345"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_176524334.1"
                     /transl_table=11
                     /translation="MSKIGIVDEQELKMLSGAAEVETRSSVPCVSLTVAVGTWVFQTSD
                     KTCPTLACSKAC"
     CDS_motif       9778..9831
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSKIGIVDEQELKMLSGA"
                     /locus_tag="CN427_RS31525_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9832..9951
                     /prepeptide="core"
                     /locus_tag="CN427_RS31525_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="0.50"
                     /molecular_weight="3878.4"
                     /monoisotopic_mass="3876.0"
                     /core_sequence="AEVETRSSVPCVSLTVAVGTWVFQTSDKTCPTLACSKAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSKIGIVDEQELKMLSGA"
                     /leader_location="[9777:9831](+)"
                     /alternative_weights="3896.4"
                     /alternative_weights="3914.5"
                     /alternative_weights="3932.5"
                     /alternative_weights="3950.5"
                     /alternative_weights="3968.5"
                     /alternative_weights="3986.5"
                     /alternative_weights="4004.6"
     gene            10001..13180
                     /locus_tag="CN427_RS29350"
                     /old_locus_tag="CN427_29350"
     CDS             10001..13180
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CN427_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29350"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_097946625.1"
                     /sec_met_domain="DUF4135 (E-value: 1.9e-107, bitscore:
                     351.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-59, bitscore:
                     192.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVKETNTMNDFNKASYLREREGNNDNQLINSNKLIDSSKLIDSD
                     ELIESWINKAGLDYDQFFERLSLQNMNKQEFLNIMYSKDTPKNSVEMSWIEDLKNILIK
                     EDTTYNLQENSYGGIGYFAQPFVRYFKNQLKNHFTEYKKDTCNLESVIKALGDALFIEL
                     KNISSRTVVLNFHELKSKQDVSSNNQFMKTYIDLYLKDYQYIYLLLKENPVLARIMVDI
                     TFKAINNSINIIERFFNDYKSIRKNFFNYSNNELILEKINIGLGDNHKGGQSVAILEFT
                     NGEKLVYKPRSLKEDICFSEFTNWLNKEGLKYPIKVINTLDKGSYGWQELIKNKECLNE
                     SDINKYYYRIGVYIAIFNLLNSTDMHYENIIASGEHPYIIDLETLFSNTLFGNKVLKYP
                     IDYLKDSVFGSGFIPNGKVFNSHYDFDLSGIGGIPKQKSEKHKGLAIVDEDNDNIRFEN
                     VPFITYEKDHLVKFNGNIINPNEYSNAIEEGLKETYCIFLRNKNKLFNIIEKSFNDCEC
                     RHILRATTVYFKFLMSSYHPQYLKNGLDRQLLFEMLWNMLRMEPKYKHLVQSEIEDLLD
                     NDIPYYTFKLNSKSIFDSRGNEYTDIFEKEALSLVKEKINDLSLKDLKRHISLVKLSLE
                     TNSISGLDVGKVEKINTFQSPNNIFGSQHLIETAEYIGEYFIQNAVPDIEDKFATWLGL
                     VNNQQNNTFDLRELDFNLYSGILGITIFLAQLAQETQEYIYKEYAEKSLNYVLGKFDGA
                     EDYLPNSMFNGLGAITYSTFYLSILWDDKNLFNKAKKFLNKMKNLKKDNQYETDFLGGH
                     AGIITFCLNLYKNTSLEDALEVAKLYGYDLLVEIKKRKNEFENNEVLTGLAHGTSGYIL
                     ALKELGHYLNNEEMNTLSQELIEYEDKLFDSIACNWLDLREQVIEKENSFYWCHGAPGI
                     ILSRALVKSIDSTSFEDTDFKRIIDKIISKKEIVERLGLCHGFFGITDICISVSKLDNT
                     LVQKEEIIKLVNKHLNQINVQEKFQGMLERGLLGLMLGVSGIGYTLLRLNNTNIPSVLT
                     LELPKSMVNKF"
     gene            13177..15372
                     /locus_tag="CN427_RS29355"
                     /old_locus_tag="CN427_29355"
     CDS             13177..15372
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="CN427_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29355"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_097946627.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.5e-41, bitscore:
                     130.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRKVPFIEQMTQTECGIACIAMISAFYGKHIPLNELREEIGNG
                     RDGNTLYDLYKASQQLEFDSKCLKATVDQLGQVNLPVILYWDSKHFVVLEKMKKGKLSI
                     LDPAFGRKTIDEAEFIKHYSGYLLELAPSQSFQKQKPKSLWKPYLKMLWEKPKILISLF
                     AINLLLQLFVLVTPTITQKIVDTMLSDSQSNTLILLLQGIVVSFVLYFIFNLLRTEVSI
                     RVSKFVDYSMSKEYFSHLLKVPYSFFQVRPSGDLLYRFSNLRSIRNMLSNQIMKTILDF
                     ILLIVIVVYMVMKSVYLTGYLMLFSLLIYIVILLFRPIINELNRNELTKDTNLYSFQTE
                     SIFGMLNIKTSGSEHMVSEKWEKHYKEFADAYVKKERVFNFMTSFSGGLTYFIPLFIIW
                     IGSYKVLDKSLTVGELIAFQTIATYFISSSNSLIFSIEAFVQLKVYLKRIRDVVDTPVE
                     YKEDAQYIKSKLQGNIELNDVCYSYTKSAENVLHNINLKIKSGQKIVIIGPSGSGKSTL
                     AKVLIGLHKPSKGQIKYDGVEFDSLDKPHMRRQMGIVTQEPFLFNQSILDNIRLNDPDL
                     SLDEVVQAAHMAQIHDEITSMPMKYETIISEMGQNISGGQRQRIAIARALVHRPKVLVL
                     DEATNALDSINETKIDGYLSTLNSTRIIIAHRLSTIVDADLIIILDGGHLVAQGSHQEL
                     MKSNAYYQSLFRNSENLDMKGGEHDEQRDEILEKSIL"
     gene            15332..15589
                     /locus_tag="CN427_RS29360"
                     /old_locus_tag="CN427_29360"
     CDS             15332..15589
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="CN427_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29360"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_097946629.1"
                     /sec_met_domain="mature_ha (E-value: 1.1e-07, bitscore:
                     23.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNEMKSWKNPYFRNSQNHATNLPIEDPLMELAEEDIKSINGGVE
                     PRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
     CDS_motif       15332..15460
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNNEMKSWKNPYFRNSQNHATNLPIEDPLMELAEEDIKSINGG"
                     /locus_tag="CN427_RS29360_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15461..15589
                     /prepeptide="core"
                     /locus_tag="CN427_RS29360_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="4389.0"
                     /monoisotopic_mass="4386.1"
                     /core_sequence="VEPRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNEMKSWKNPYFRNSQNHATNLPIEDPLMELAEEDIKSIN
                     GG"
                     /leader_location="[15331:15460](+)"
                     /alternative_weights="4407.0"
                     /alternative_weights="4425.0"
                     /alternative_weights="4443.0"
                     /alternative_weights="4461.0"
     misc_feature    complement(15612..15625)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 20.25"
                     /tool="antismash"
     CDS             complement(15626..15709)
                     /gene="allorf_39377_39460"
                     /locus_tag="allorf_39377_39460"
                     /protein_id="allorf_39377_39460"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSFQKCIFNINNNYAFMCNYDSNVMPF"
     CDS_motif       complement(15659..15709)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSFQKCIFNINNNYAFM"
                     /locus_tag="allorf_39377_39460_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15626..15658)
                     /prepeptide="core"
                     /locus_tag="allorf_39377_39460_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1171.3"
                     /monoisotopic_mass="1170.5"
                     /core_sequence="CNYDSNVMPF"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSFQKCIFNINNNYAFM"
                     /leader_location="[15658:15709](-)"
     gene            15799..16056
                     /locus_tag="CN427_RS29365"
                     /old_locus_tag="CN427_29365"
     CDS             15799..16056
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="CN427_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29365"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_097946631.1"
                     /sec_met_domain="mature_ha (E-value: 1.1e-07, bitscore:
                     23.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSINGGVE
                     PRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
     CDS_motif       15799..15927
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSINGG"
                     /locus_tag="CN427_RS29365_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       15928..16056
                     /prepeptide="core"
                     /locus_tag="CN427_RS29365_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="4389.0"
                     /monoisotopic_mass="4386.1"
                     /core_sequence="VEPRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSIN
                     GG"
                     /leader_location="[15798:15927](+)"
                     /alternative_weights="4407.0"
                     /alternative_weights="4425.0"
                     /alternative_weights="4443.0"
                     /alternative_weights="4461.0"
     gene            16113..16370
                     /locus_tag="CN427_RS29370"
                     /old_locus_tag="CN427_29370"
     CDS             16113..16370
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="CN427_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29370"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_097946631.1"
                     /sec_met_domain="mature_ha (E-value: 1.1e-07, bitscore:
                     23.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSINGGVE
                     PRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
     CDS_motif       16113..16241
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSINGG"
                     /locus_tag="CN427_RS29370_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       16242..16370
                     /prepeptide="core"
                     /locus_tag="CN427_RS29370_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.10"
                     /molecular_weight="4389.0"
                     /monoisotopic_mass="4386.1"
                     /core_sequence="VEPRGWGDVLTTLLCFVGSYTLGNDGIMCTTSYECQRKGSCA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNELKSWKNPYLRNSQNHATNLPIEDPLMELAEEDIKSIN
                     GG"
                     /leader_location="[16112:16241](+)"
                     /alternative_weights="4407.0"
                     /alternative_weights="4425.0"
                     /alternative_weights="4443.0"
                     /alternative_weights="4461.0"
     gene            16429..19611
                     /locus_tag="CN427_RS29375"
                     /old_locus_tag="CN427_29375"
     CDS             16429..19611
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="CN427_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CN427_29375"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_097946633.1"
                     /sec_met_domain="DUF4135 (E-value: 2.8e-112, bitscore:
                     367.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.7e-69, bitscore:
                     224.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNYMYRALTLGERKKLQLHNSEKVDLEYAIPFWTKLLKNANQDK
                     LNEALNNIHNIDTEFISKNFDIEDGVDFQINDEWFQFLNDIKMENIIEHSTLQTENRFI
                     NKITNQPFSPFFKPYIESFEKEFFDNSKLPVKEILSEECKLGIVKHLYEMLFDISHKTL
                     ILEINTLRMTNELKGKTSEERYESFCDLFQKDSVYHNKLVEEYPVLFRLIANKILNFKN
                     FLNELLSNYILDKKEIEIEFNDSNEIQYITNIKLGSGDSHKKGRTVSILELDNDNKIIY
                     KPRSLSIDVEFQKFLEWVNEKSRNSIPLKVMKFIDKEIYGWSEFIETKECNDEIQLQHF
                     YNRVGQLLAIVHVMNATDFHYENLIANGEYPVLIDLESLFHHTIMPDHELTKSEVVNKA
                     LMTVRDSVLSTGLIPGQVHNGKNANNNFDVSGISGGSEQIIPFKVGVIENHYSDEIKIE
                     KQQGILLPAGNLPKLKEKEIDIVNYLKYLNQGFEHVYSWFIENRDSLADRLKMFADQPV
                     RRIFKNTLNYAKLLRLGYHPDFLRNQIDREILFYRLWEENNEENSLRDLSIHEIQDMLE
                     GDIPYFTSRPNENKIWSSNEAQINNFYYKNGLDLSIEKINTINLENMEYQLSIINSTFS
                     AAYSENEINLLNFNSIDKKNTQNPEENLLESAKHIADILIKNAIKHEGIKGKEYCWTSM
                     VLKGTDETSWVYSITGPGLYDGNSGISLFFAYLWKITKNEVYKEAAYAAFRPIRTLIPH
                     LPETKGISIGSFLGVSGVLYTFHHLAVIFDDREMLDEGLNYAKQLEKSIPNDRIYDLIG
                     GSAGAIFVLMNLYEHLKEEWLLELATKAVQHLKEHKIPQSKGLCWPPPNNEEKPYISYS
                     HGNAGIIAALTKYYKYSKDEEIIPLISEALIYENSFYSESKKNWYCVQTDDYPTAWCHG
                     AAGILLGRSLMKKNGFTSETINNDITHALETTLNPNLGANYSLCHGDLGIIDILFKFNE
                     YFSNQINESILDDLIQQINKRMFSGENEIKADLNSVGLMNGIAGIGFGLLRLYAPNQIP
                     SILALDSPKIKL"
ORIGIN
        1 tattttttgt tttgtcgcaa taggtactgc cacatacaaa tataacttac ctgaaaattt
       61 cgttggatgg ttatcagtaa tagcaaaatt cattatactt ttcgctttcc tatttggtat
      121 tcaatatctt attactaaat ttacatggta caaaaataat aaaaactaat aaatatagct
      181 cttcctaatt aggaagagct atatttattt tatttaagaa gtcatttttt gttgatttga
      241 taaaagttgg tatagtttat tactcttaat taattgatcg tgtgtaccaa accccgaaac
      301 ttccccctga tctaaaacaa caatttgatc agcgttttga atagtagaaa tacgatgagc
      361 aattacaata gttgtttttt tataaataag attatctaat gcatgtttaa tcatattttc
      421 tgaattagta tcaagatttg cagtagcctc atccaataat aaaaatggag tatctcttaa
      481 aaatgcccta gcaatagata tacgttgttt ttgacctcct gaaagattaa ttcctctttc
      541 acctaaaaca gtattatatc catctgaaaa acttgttata aactcatgac agtttgccaa
      601 aatagatgct tttataattt catcttcaga aacttctctt tgaataccat atgtaatatt
      661 ttcacgaatt gtacccacta atatagggca atcttgtgaa acataactaa acatagatct
      721 ccatttatca aggtctatat tcaaatgaga ttttccatct aataaaattt cccctttaag
      781 aggatcataa aatctttcta ataaataaaa taaagtagtt tttccaactc cactaggacc
      841 aacaagtgca gtaacagtat taggcataat tttcaaatta atattttcaa aaatactttt
      901 ttcatcataa gcaaaaccaa tatccttaaa ttctaatgtt ccaaatgatg gttcctctaa
      961 aaagtcatct ttattttttt catctttttc atctaaaata ttaaaaattc tttccgtaga
     1021 ccctttagca gattgaacat ttgtaataaa gcgactcatt acacccactg gtcctacaat
     1081 ttgaaataaa tataaaataa atgctaataa ttcaccagaa gaaagataac cttcacttac
     1141 tctatatgaa ccaaatccaa ccacaaccac tataataaga gtaattgata cagtcattaa
     1201 tggaattaaa atagactcta tttttgctct ttttatccca tttacatata attcttctat
     1261 tttctttttt cctctttcaa attcaaaatc ttccgtacca taagatttta ttaaacgaat
     1321 ttctccaaga acctgagaaa gcaaagctgt aaattctgac attttttctt gttgttcata
     1381 agatatttta taaatctttt tactaattgg tataactata aataaagtaa ctggaactgc
     1441 agataaaagt gttaaagtca taggcacatc taataaaaac aaaataacaa cagcaccaat
     1501 catagataat ccacttgaca gcaaatcagc aatttcactt gataataaat tcatagtaac
     1561 tgttgtatca ttagtaacac gactaataat ttcaccaggt tgatttttac tataaaaatc
     1621 aactttaaga tttaaaactt ttctccatat catttttctt aaattaagaa caaccctttg
     1681 tccaaccaaa gataaaagat acaaagaaag tgccattgaa ataatctcta caattaataa
     1741 aactaaaact aaaaataata attcatatga aaaaccttta gaaagttgtt caatttgctc
     1801 ttttaatatt aagggtataa ttaaagaaca aactgaatta attaagccaa atattacccc
     1861 caaaaaaagt gtaactttag gtggtgttgt aattttccat aatgctttta aactaacatc
     1921 tttatctttc tccataatgc atgtactcct tcatctatta tttaattgaa taatacccat
     1981 ttcttaaaat taggatctat taaatataat caaaaataaa tgatatatat aaatatatct
     2041 aactaaataa tcagtttttt gaaacatagt catcaataac attttattat cataatatta
     2101 tttaaacaag atttaatttt acaaaattat cattaaatgc aaaaaaatac aaaaataaaa
     2161 gaaggtaaaa tataatggga gcacttttta aagctggttt aaaggctgct actgatggcg
     2221 caggcggttg cggtgcagaa agactttaga attggtataa taaataaaaa atccagctnn
     2281 agctggattt tttatttatt tatatttata tactgataaa aagattatta cttaattctt
     2341 ttacctgtat aaccttcaac taaaccttta taaaattcca tataattagc ccacatttaa
     2401 cattcacctc ccatcacatt tcattaaata attaaacatt atctaaacca accaccaatt
     2461 gcacgaccaa tatcacgcca cataattctc acctcttttt tataaatcat atatataaat
     2521 atacacttga aaaaaatgta agtcaatata tttatgggaa ttattacata aaattcaaaa
     2581 aatatataaa aataataaaa aataaagaag ctatcaggtc catcggaagc gttttcaacc
     2641 cccttttgta acagttgttt ttaaataatt aaaacgaagg tagtcctaat tttaatttca
     2701 atcttctgat aactgtggtt aggaactgca attagagaaa ttccatacca ctgtggacca
     2761 agggtagtcg caatatgacc tagaccagat gaaacctgag aaacttttga atgatatgtt
     2821 caagaaattc ttcttgaaac tcagagagat tattgtgtgt aaatacaaac tgcttcatta
     2881 ggaggtattg ctattttgtc ctcaataata gcggtttctc tatctgaaac tttccaagca
     2941 tatttacttg ctgtaagatt aatagaacta cccttaatat ttagtggata aatcgttatg
     3001 ttttcccctt taattaactc cctttttata tcgttgtcac ttagtaacaa tgacttctcc
     3061 ctctattaat atattataat ccctaattta caataccata caatagcatg ataataaaat
     3121 ttgtttaata accttctttc attaacacaa tcctcctttt atgataagaa aagggattga
     3181 atcatttaac agctttttta gtttgagaaa tttttttttg tttcattaat tttttaattt
     3241 gattggccat aaaccctaat actttatctc ttaaaactaa tgaaagaata atagagatta
     3301 taaatatgaa aaaatagcac aattataaat gccaatactt atgtattcgc ttagtataag
     3361 ttatttcata aattatactg atttatatta aagatgaccc tatttatata ttatgatgca
     3421 attctgtaaa aataagtaca cccattattg aatgtactta ttcccaaaat ttccaccagg
     3481 atttcctttt tgctgccgct atttcttcct gggcggatac aatagtacgt tttgcatctt
     3541 gaatctctcg gaccatcttc ataagattat catcccttag ttctaacctc ttttctatct
     3601 tttcttcacg ttccttacga tctttcatat cttccacgat taatttattc ctttctttca
     3661 catcctcttc gattaatttg tttctttgat ctatacgatt accgagtctc ttttccattt
     3721 ctaataggtt agcttgctgc accttattaa tttcttctat catagcgcta tattgttgct
     3781 ggaattgata ctgcatttga tatggaacta gatcttcccc ctgggattcc tctttcttat
     3841 tatcgatccc aaactgcttt gcaatcattt tcgcagcttt ttctaaagtc ataccatttt
     3901 gtttactcaa ctctactaat tgttcaatga gtacaacatc aaaccctgta tattcccttc
     3961 ttcctcgact attctttctt acatcatatc cttcacgttc aagaatatcc gaatactttc
     4021 tcagggttcc tccacttatt cccaaatgac tatagacctc attgctggta tataatctcc
     4081 gcttttgaca tagcgctatg ccacctccta ttagagaatt tcaatataga agggctgaaa
     4141 cctttaagaa ttcatcgacg aaactcgtat ggtccttgca atgttttgtc aaaattatac
     4201 acatccagat agcgccataa ttaaagataa aacgctttta aataaaccca ttacacagta
     4261 aaaaagaaaa acacctgatt cagactaacc aagtgttttt tagttcttta taaatttagt
     4321 tggtccgttc acaatgactt caacttgaat ggatcttgct tttcaatacc aattacaatc
     4381 ttttttagag tgctagtatc agtatgttta agtttgatag accatttttt ttcatataca
     4441 tcaaagtttt tgcaccagaa ccctaaatag agccttatat ttagtgataa atacgtacgg
     4501 ttcggagtat ttggaaacct accatagaaa tataacaaga cgctgggatt tcccctactt
     4561 tacagatgta taattattgt aatagactaa taataattta caataaatac atgtacataa
     4621 aaaaggagag ataaaatgtc atatggagag tggtttccaa ttttacttgc actagccatt
     4681 gctatatatt atggtgctaa gaaaaagaaa aaataaaaac tatatataag tttaaattaa
     4741 aaaatatacg agtaccgaaa gggcaatgga atctatacat tataatgtgt agattttttt
     4801 gtggaataca ttattttatg taagataatt atgcgggaaa atgactttta gtcaaaaaaa
     4861 tttaactaaa agtcaaaaaa atttgactaa aagtcaaaaa aatattacac tcctcttata
     4921 agagaggtga tggtatttat gatagacgga aaattacaga atcaattgta tatttttcga
     4981 gcaaagaaaa aatggtcaca aaaagaattg gcagaaaagt tgggagtaag taggcagact
     5041 attatttcac tagaaagtaa tcggtatagt ccttcgctag tattagcttt taagattgca
     5101 accttatttg agagtgatat taatgaaatt tttaaatacg aagtgaaagg agaatcagaa
     5161 attcaatgat agataatata cttactgtag taatgtttat ttttacaatt ccaatggttt
     5221 atataatgat gttttcttcg aaagaaaaag atgaaagagg taaacaaatt ataaatactt
     5281 catttcacaa tgcatatttt attttattgt taggcatatt tttggtggtt ataagtagta
     5341 aattagccat atttgatatg gattttcaaa catttggtaa tctaatcgta ttagcaattt
     5401 tgatatcatt aatagtagca ggaatgaata tttttattaa caatagaaga atgtaagttt
     5461 atcatctgtt tattataaat tctatctaat atattagatg gaagttaaag agagaggggt
     5521 attaggtttg gggattccaa tcgttcaatt aaaaaatgtt aataaggttc taggaaataa
     5581 aacaattatt gaagatatga attttgaagc ttatgaagga gaggtatttg gttttttagg
     5641 tcctaatgga gcaggaaaaa ctacaacaat taggatgatc gtaggactgg ctaatcctac
     5701 acgaggggat attctgatag acggaaactc aattatacat aaaagaaaat tagctataaa
     5761 aaaagttggc gctatagttg aaaatcctga gctttataaa tttatgacag gttatcaaaa
     5821 cctgaaatat ttcggcagaa tttatgggaa tgtaacgaaa gaaaaaatag atgagatagt
     5881 tgaattagta gatttaacag ctagtattca tgataaagtt aaaacatatt cccttggaat
     5941 gagacaacgt ttaggtattg cgcaagctct tcttcatgat cctaaagtat taattttgga
     6001 tgaaccaaca aatggattag accctgcagg gataagagaa attcgtgagt acttacaata
     6061 tttagctcac gaaaaaaaaa tgtgtattat tgtttctagt catttattaa ctgaaatgga
     6121 acttatgtgt gatagaatca tcattataca aaatggtaaa gttgtggata cacaatctgt
     6181 ccgggaaaac agaaaagaaa atgaagtgtt atttgaggtg aaacacccac aacaagctag
     6241 agaagatatt ttagcagtat acagcgaatt ggatattgaa tgtttggata atcttattaa
     6301 agtctgtatt aaaaaagaag aaattccttt aataataaac cttttgtcaa aaaataatca
     6361 tcaagtctat ggaatcaaag agactgccat ttcattagag gagagattct tagagattac
     6421 tgggaaaggg gaaaggaaac atgttagtac ttattcaaaa tgaattaatt aaaatactaa
     6481 gacgcccagg gacatatata atggctggca tgattatact tcttgtaatt ggtgctggag
     6541 tacttacgaa atataatgtc agtaaaaatg tttatggtga tgattggaaa gtagttcttg
     6601 agagtgaaaa taaaaatcta actgagaaaa gtaaagagtt aaataaaggt acattagctt
     6661 atgaaaaaat gcagcaaaca atagcagaaa atcaatatag aattagtaat gatttaaaac
     6721 caaatagttc agttaatact tggacttttg ttaaagctgc ccaggctatt atttccgttg
     6781 taggattatg cactattgtt atagcagcaa gtattgtttc ctcagaattt agtcgaggaa
     6841 ctattaaact aataatgatt cgtccatcat cccgctggga agttttattg gctaaatatt
     6901 tatcagtaat aatattcgga ttcgtaatgt tgtttttatt gtttgcacta gctttcctat
     6961 tcggtttatg tctatttgga atttctggtg agaatataca ccttgttttt caacaaggaa
     7021 aagtaataca agaaaatatg gttggttatt taatcaaatc atatttgctt tcatcagttg
     7081 acttactttt gatgtctaca atggcgttca tgatttctac agtattcaga aataattcat
     7141 tagctttagg tatttctcta ttttcgtatt tatcaggtga tatggttacg agattaattg
     7201 cacaaaaatt tgatggggca aagtatatct tatttgctaa tactaatcta acaatgtata
     7261 cagatggaga tgtattggtg aaagggatga cgccaacatt ctctataaca attttatctt
     7321 tgtatttagt cttcttcttg tctgtgtcgt ttgtttcttt ttctaaaaga gatatattat
     7381 aaatctaata attaaataca tagttaggag tatacttaat atgaaaaagt tacttaaggg
     7441 taatattatc tatatgttat gtggtgggat ttggtgtttt atgataatga acatatataa
     7501 aatttggaaa gaataatctg aaatataaat tctctgttta ttacttttat attataaaag
     7561 tagccaaaaa tttcctgttg ggaagttttt ggctactttt tttacgattt aatgagttac
     7621 tgctttatat acatctaata taccattacc aaagtggtct ttgtttttga tttcattatt
     7681 tacaccatat ttataaagaa aattagtagc ttttttaggt tgatctttaa aatgatactt
     7741 atcaataata agtgcaagag caccagatac ttttggagcg gcagtagata ctccagacga
     7801 gtagaaatat ccccccattg gagatgtact taatatggac tcttttgcaa accatttatc
     7861 atttacccat gcatcttttc catatgtatc tagtaatcta gtatcccctc caggagcagc
     7921 aatatctaca aagtgtgctc cgtaattaga aaataaagaa agctcattcg aaggcccgat
     7981 tgatgaaacg gttactacat ttggtagatc tgctggtgca tctagaactt ctcctttgaa
     8041 agtaattcca tctttctcat attttttgtt ataaaattct gcaacttgtt ttttatctct
     8101 catattaaga gaatcattgc ctgcagcagc aacaactata cttccttgtt ttctagcaaa
     8161 attaatagcc tttttatatg ctttaatttc tgcaatgtct tttttagatt ttccattggc
     8221 tgagaatgtt gtcccattta taagataact acctaaactt aaatttataa catcaacatc
     8281 atctttagca gcttctacaa ttccttttat aacccatgca gattctcccg aactacttcc
     8341 gaaaactcta taggatttaa ttcctacatc aggagcaact cctttgatgt tgccattagc
     8401 cgccacaagt ccagctgtgt gtgtgccatg cccacggaaa tctgttaact gattaacatc
     8461 tccagtttct tgcggttctc cccctttata ccctcctaac ggtaccaagt ttttagaacc
     8521 aggaacaata ttgtttttta aatctggatg gttaatatct aatcctgaat ctacaatacc
     8581 aacagttaca ttcttagagc cagaaaatac tttgtaactc tccccgttat ttgtaacttt
     8641 ttgcatatcc cactgagatt cccatagaac tggtaaagtt ctcacattta tagatttgtt
     8701 tatttcttca tgagaatctg ttaattttag agatttatta tatgtatcaa ttgtatctat
     8761 tttacttata tttttaattt cactttcagt tgatctgact tgtacaaggc ctacttcagg
     8821 tacagtatat acaatttgag tattatgggc actaattttt tttattgttt cttgagtttc
     8881 cttttcgtct tttactaaaa tggtgtaata atctttagtt tcctcagcgt aagtattgtg
     8941 aaatggtgta agtactacaa ataaggctaa caaagctata aaagaaaata tctttttcaa
     9001 attatttctc tccctttcaa atttttacag taataaaaca aaaatattct atcattttac
     9061 ttttaaaaaa gcaaaatatg taaatatgca tatttagttg ttaatttact attttttaca
     9121 taaaattaga tgcaggttaa ttttacaaat tgtgaattat gaaagatcta tcattttact
     9181 tttaaaaaag caaaatatgt aaatatgcat atctgattgt ctatttacta ttttttacat
     9241 aaaattagat gtgaattaat tttacaaatt gtggattgta acagatataa ggtaataaaa
     9301 atggtttatt aactattaac actgttacaa attattttgt taatagaatg taaatttgta
     9361 gaaatacagt atattcttct aggatttaat gtttagaata aaaaaacaga taattccctc
     9421 aaaaaagaat attttttcga aaaaagtatt gaaattattt gaaaaatttt atataacagt
     9481 gaagggaggt gaaaaaaatg gtagaaaagg aaaaaatgtc taaagtaatt ggtgttgtag
     9541 atgagcacga actaaaaatg ttatctggtg ctgcggaagt agaaacaaga agttcacttc
     9601 catgtgctgg cctaacagtt gctgttggaa cttgggtttt ccaaacatca gaaaaaactt
     9661 gtccaacttt agcatgttca aaagcttgct aataaggaag aatcaacatt catgttaaaa
     9721 aaatctataa acttatatat taaattgatt ggggatagaa aaatggaaaa aaataatttg
     9781 tctaaaattg gtattgtaga tgaacaagaa ttaaaaatgt tatctggtgc tgcggaagta
     9841 gaaacaagaa gttcagttcc gtgtgtaagt ttaacagttg ctgttggaac ttgggttttc
     9901 caaacatcag acaagacttg tccaacttta gcatgttcaa aagcttgcta attaataaaa
     9961 aataaaaagg aaataatctc tatttttggg gggaccttag atgtacgtaa aagaaacaaa
    10021 tactatgaac gattttaata aagctagtta tttaagagaa cgagaaggaa ataatgataa
    10081 tcaattaatt aattcaaata aattaattga ttcaagtaaa ttaattgatt cggatgaatt
    10141 aattgaaagt tggattaata aagcaggatt agattatgat caattttttg aacgattatc
    10201 attacagaat atgaataaac aagaattttt aaatattatg tacagtaagg ataccccaaa
    10261 aaatagtgta gaaatgagct ggatagaaga tttaaaaaac atcttaataa aagaagatac
    10321 tacatataat ttacaagaaa attcttatgg aggaattggc tactttgcac aaccgtttgt
    10381 tcgctacttc aaaaatcaat taaaaaatca ttttacagaa tataagaaag atacatgtaa
    10441 tttggaaagc gtaattaaag ctttaggaga tgcgttgttt atagaattga aaaatattag
    10501 tagtagaaca gtcgtattaa attttcatga attaaaaagt aaacaagatg tatcttctaa
    10561 taatcaattt atgaaaacat atattgattt gtacttgaaa gattatcaat atatatattt
    10621 attactaaag gaaaatcctg tattggctag aataatggtt gatataactt tcaaagctat
    10681 taataattct ataaatataa tagaaagatt ctttaatgat tataagagta tccgtaaaaa
    10741 tttctttaat tacagtaata atgaattaat attagaaaaa ataaatattg gtttaggcga
    10801 taaccataag ggtggacaaa gtgtagcaat attagagttt acaaacggag aaaaattagt
    10861 atataaacca agatctctta aagaggatat ttgtttttct gagtttacaa attggttgaa
    10921 taaagaaggg ttgaagtatc caattaaagt tattaatact cttgataagg gttcttatgg
    10981 ctggcaagaa ttaataaaaa ataaagaatg cttaaatgaa agtgatatta ataaatatta
    11041 ttatcgaata ggtgtataca tagcaatttt taacctttta aattcaactg atatgcacta
    11101 tgaaaatatt attgcttcag gagaacaccc atatattatt gatttagaaa cactgttttc
    11161 taacacatta tttgggaata aagttttaaa atatcctata gattatttga aggattcagt
    11221 ttttggttca ggatttatac caaatggtaa ggtatttaat tcccattatg attttgattt
    11281 aagtggaatt ggtggtattc caaagcaaaa atctgaaaaa cataaaggcc tagctatagt
    11341 tgatgaagat aatgataata ttcgatttga aaatgttcca tttattacgt atgaaaaaga
    11401 tcatttagta aaatttaatg gaaatataat taatccaaat gaatactcaa atgcaataga
    11461 ggaaggcttg aaagaaacct attgtatctt cttaagaaat aaaaataaat tatttaatat
    11521 tattgagaag tcttttaatg attgcgaatg taggcatata ttaagagcaa ctactgttta
    11581 ttttaaattt ttaatgtctt catatcatcc tcaatatctt aaaaatggat tagatcgaca
    11641 attactattt gaaatgcttt ggaatatgtt gagaatggaa cctaaataca aacatcttgt
    11701 acaatctgaa attgaagatt tactagataa tgatattcca tactatactt ttaaattgaa
    11761 ttcaaaaagt atatttgata gtaggggaaa tgaatatact gatatttttg agaaagaggc
    11821 cttaagttta gtaaaagaaa aaattaatga cctaagctta aaggacttga aaagacatat
    11881 ttccttagta aaattatctt tggaaacaaa ttccattagc ggtttggatg ttgggaaagt
    11941 agagaaaatt aatactttcc aaagtcctaa taatattttt ggaagccaac atttgataga
    12001 aacagcagaa tatataggtg aatattttat tcagaatgca gtacctgata tcgaagataa
    12061 atttgcaaca tggttgggct tagttaataa tcagcagaat aatacatttg atttaagaga
    12121 attagatttt aatctttata gtggtatatt aggaataaca atatttttag ctcaattggc
    12181 tcaagaaaca caagaatata tttacaaaga atatgctgaa aaatcattaa actatgtttt
    12241 aggaaaattt gatggtgctg aagactattt acctaattca atgtttaatg gattgggagc
    12301 aattacttat tctacttttt atttatctat tctatgggat gataaaaatt tatttaataa
    12361 ggctaaaaaa ttcctgaata agatgaaaaa tcttaagaaa gataatcaat atgaaactga
    12421 ttttttaggt ggacatgcag gtattattac tttttgctta aacctttata aaaatacaag
    12481 cttagaagat gcattagaag ttgctaaatt atatggatat gatctattag ttgagattaa
    12541 gaaaagaaaa aatgaatttg agaataatga ggttttaact ggtttagcgc atggtacttc
    12601 aggttatatt ttagctttaa aagagctagg acactatctt aataatgaag aaatgaacac
    12661 actgtctcaa gaattaatag aatacgaaga taaacttttt gattctatag catgtaactg
    12721 gttagatctt agggaacaag ttatagaaaa agaaaattca ttttattggt gtcatggcgc
    12781 cccaggaatt attttatcac gtgccttagt aaagagtatt gatagcacaa gctttgagga
    12841 tacagatttt aagagaatta tagataaaat tatttcaaaa aaagaaattg tagaacgttt
    12901 aggcttatgc catggtttct ttggaattac tgatatttgt ataagcgtat cgaaactaga
    12961 taataccttg gtacaaaaag aagaaattat caagttggta aataaacatt taaatcaaat
    13021 aaatgtccaa gaaaaatttc aaggtatgct agagagggga ctattaggtt taatgttagg
    13081 agtttcaggc attggttata cgcttttaag attaaataat actaatattc catcggtact
    13141 taccctagaa ttaccgaaaa gtatggtgaa taaattttga agaaaagaaa agttcctttc
    13201 attgagcaaa tgacgcagac agaatgcgga atagcgtgta tcgcaatgat atccgcattt
    13261 tatgggaaac atataccttt aaatgaatta agagaagaaa ttggtaatgg aagagatggt
    13321 aatactttat atgatttgta taaagcatca caacaattag agtttgattc taaatgtctg
    13381 aaagcaactg ttgaccagtt aggtcaagtg aatttaccag ttattttgta ttgggatagt
    13441 aagcactttg ttgttttaga gaaaatgaaa aagggcaaat tatccatttt agatccagcg
    13501 ttcggaagaa aaacaataga tgaagctgaa tttataaagc attattcagg ttatctatta
    13561 gaattagcac cgagtcaaag ttttcaaaag caaaagccta agagtttatg gaagccatat
    13621 ttaaagatgt tatgggagaa accgaaaata cttatttctc tctttgcaat taatttatta
    13681 cttcaacttt ttgtattagt aacacctact attactcaaa aaatagttga tactatgttg
    13741 agtgatagtc aaagtaatac cttgatttta ttgttacaag gaatagtagt ttcctttgta
    13801 ctatatttta tatttaatct tttacgtacc gaagtttcaa ttagagtatc aaaattcgtt
    13861 gattatagta tgtcaaaaga atattttagt catttattaa aagttcctta tagctttttt
    13921 caggtgagac catctggtga tctactatat cgtttttcaa atttaagaag tattagaaac
    13981 atgctttcta atcaaataat gaagactata ctagacttta ttttattaat agtgatagtt
    14041 gtatatatgg ttatgaaatc agtgtattta acaggatacc taatgctttt ctcattacta
    14101 atatatattg ttatattgct tttcagacct ataattaatg aattgaaccg aaatgagtta
    14161 acgaaagata caaatttata ttcgtttcaa actgaatcta tttttggaat gctaaatatt
    14221 aaaacttctg gttcagaaca tatggtttca gaaaaatggg aaaaacacta taaagaattt
    14281 gctgatgcat acgtaaaaaa agaaagagtg tttaatttta tgacctcttt ctcaggtgga
    14341 ttaacatatt ttataccctt attcattata tggattggat cttataaagt acttgataag
    14401 tctttaacag taggtgaact gattgcattt caaacaattg cgacatattt tattagctca
    14461 tctaattcat taattttctc tatagaggca tttgtacaat tgaaagttta tctaaagaga
    14521 atacgtgatg tagtagatac tcctgttgag tataaagaag atgcacaata tataaaaagt
    14581 aaacttcaag gaaatataga gttaaatgat gtttgttatt cttataccaa atcggctgaa
    14641 aatgttttac ataatattaa tttgaaaatt aaatctgggc aaaaaatcgt tattatagga
    14701 ccttctggtt cagggaagag tactttagct aaggtgctga ttggcttaca taaaccttcc
    14761 aaaggtcaaa ttaaatatga tggagttgaa tttgactcct tagataaacc tcatatgaga
    14821 aggcaaatgg gaattgtaac tcaagaaccg tttttattta atcaatctat tctggataat
    14881 attaggctga atgatccaga tttatcgctt gatgaggtag tccaagcagc acatatggct
    14941 caaatacatg atgaaattac atctatgcct atgaaatatg aaacaattat atcagaaatg
    15001 ggacaaaata tttctggagg acaaagacaa agaattgcca ttgcgcgtgc tcttgttcat
    15061 cgacctaaag tcttagtttt agatgaggcc acaaatgctt tagatagtat taatgagact
    15121 aaaattgatg gatatttatc aacattaaat tctactagaa ttattattgc acataggctt
    15181 tcaacaattg tagatgcaga tttaattatt attttagatg ggggacatct ggtcgcacag
    15241 ggatcacatc aagaattaat gaaatcaaac gcatattatc aaagtctctt tagaaatagt
    15301 gaaaacttag acatgaaggg aggtgaacac gatgaacaac gagatgaaat cctggaaaaa
    15361 tccatacttt agaaattctc aaaatcatgc tacaaatctt ccaattgaag atccattaat
    15421 ggaacttgca gaggaagata ttaaaagcat taatggtggt gttgaaccaa gaggttgggg
    15481 agatgtttta acaactcttt tatgctttgt tggtagctat acacttggaa acgacggaat
    15541 tatgtgtaca acttcatatg agtgccaaag aaaaggaagt tgtgcctaat cagtaaaaaa
    15601 tttgtgtgaa tgaaactaaa gtttgtcaaa atggcattac attagagtca taattacaca
    15661 taaaagcgta attattattt atattgaaga tacatttttg aaaagacatt acatagatga
    15721 agaaatggat taactgtccc ttactatgga gtatcttata gaaataagaa aatttagcac
    15781 aaaaaggaga taattataat gaacaacgaa ttaaaatctt ggaaaaatcc atatttaaga
    15841 aattctcaaa accacgctac aaatcttcca attgaagatc cattaatgga acttgcagaa
    15901 gaagatatta aaagtattaa tggtggtgtt gaaccaagag gctggggaga tgttttaaca
    15961 actcttttat gctttgttgg tagctataca cttggaaacg atgggattat gtgtacaact
    16021 tcatatgagt gtcaaagaaa aggaagctgc gcttaattag aaaaaaatgt atgaataaaa
    16081 ctaaaattta atacaaaaag gagataatta aaatgaacaa cgaattaaaa tcttggaaaa
    16141 atccatattt aagaaattct caaaaccacg ctacaaatct tccaattgaa gatccattaa
    16201 tggaacttgc agaagaagat attaaaagta ttaatggtgg tgtcgaacca agaggttggg
    16261 gagatgtttt aacaactctt ttatgctttg ttggtagtta tacgcttggt aatgatggaa
    16321 ttatgtgtac gacttcatat gaatgtcaaa gaaaaggaag ctgtgcttaa tcattaaaag
    16381 agaaagggga gagccctttc tctatattta tttaggagcg ataatagaat gaataattat
    16441 atgtatagag cattaacttt gggggaaaga aaaaagttac aattacataa ttcagaaaaa
    16501 gtagatttag agtatgcaat accattttgg actaaacttt taaaaaatgc gaatcaagat
    16561 aaattaaatg aagcacttaa taatatacat aatatagaca ctgaatttat tagtaaaaat
    16621 tttgatattg aagatggagt agatttccaa attaatgatg aatggtttca atttctaaat
    16681 gatataaaga tggaaaatat aattgaacat tcaacgcttc aaaccgaaaa tagatttata
    16741 aataaaatca ctaatcaacc attttcccca tttttcaaac cgtacataga gtcttttgaa
    16801 aaagaatttt ttgataatag taagctacca gttaaagaga tattatcaga agaatgtaag
    16861 ctcggaattg tgaagcactt atatgaaatg ttatttgata ttagtcataa gacattaatt
    16921 ttagaaatta atactttacg tatgactaat gagctaaaag gtaaaacatc tgaagaacgt
    16981 tatgaatctt tttgtgattt attccaaaaa gatagtgtct atcataataa gctagtagaa
    17041 gaatatccgg ttttatttag attaatcgct aataaaattt taaattttaa aaatttcctg
    17101 aatgaattgt tatcaaatta tattctggat aagaaagaaa ttgaaataga gtttaatgat
    17161 agtaatgaaa tacaatacat tacaaatatt aaactaggaa gtggtgattc acataaaaaa
    17221 ggaagaacag tttccatttt agaattggat aacgataata aaattatcta caagccacgt
    17281 tctttatcta ttgatgttga atttcaaaaa tttttagaat gggttaatga aaaatctaga
    17341 aatagtatac ctttgaaagt aatgaaattt atagataaag aaatatacgg atggtcagag
    17401 tttattgaaa ctaaagaatg caatgacgaa atacaattac aacattttta caatagagtt
    17461 ggccaattac tggctattgt tcatgtaatg aatgcaacag attttcatta tgagaatctt
    17521 attgctaatg gagaatatcc ggttctaatt gatttagaat ccttgtttca tcatacaatc
    17581 atgccagatc atgaattgac aaaaagcgaa gtagtaaata aggctttaat gacagtgaga
    17641 gattctgtat tatccacagg attaattcct ggccaagttc ataacggtaa aaatgcaaac
    17701 aataattttg atgttagtgg tatcagtggt ggatctgagc aaattattcc tttcaaagta
    17761 ggagtaattg aaaaccatta ttctgatgag ataaaaatag agaaacaaca aggcatatta
    17821 ttacctgctg gaaatttacc aaaattaaaa gagaaagaaa tagatattgt taattatttg
    17881 aaatacttaa accaaggttt tgaacatgta tattcttggt ttatagagaa ccgtgattcc
    17941 cttgctgata ggttaaagat gtttgcagat caacctgtaa gaagaatctt caaaaacact
    18001 ttgaactatg ctaaattgct tcgtttgggt tatcatcctg atttcttaag aaatcaaata
    18061 gatagagaaa ttctttttta tcgactatgg gaagagaata atgaagagaa ttctctaagg
    18121 gacctttcta tacatgaaat acaagatatg ttagaggggg atattccata tttcacttct
    18181 agaccaaatg aaaacaaaat ttggagttcg aatgaagccc aaataaataa tttttattat
    18241 aaaaatggat tagatttaag tattgagaaa attaacacca ttaatttgga aaatatggaa
    18301 tatcaattat caattattaa ttctacattt tctgcagcgt attctgaaaa tgaaattaac
    18361 ttgttaaatt ttaattctat tgataaaaag aatactcaaa acccagaaga aaacttgttg
    18421 gaatcagcta aacatattgc tgatatttta attaagaatg cgatcaagca tgaagggatt
    18481 aagggaaagg aatattgctg gactagtatg gtattaaaag gtacagatga aactagttgg
    18541 gtatattcta ttacaggacc agggttatat gatgggaatt caggaatttc tttattcttt
    18601 gcatatttat ggaaaataac caaaaatgaa gtttataaag aagctgctta tgctgctttt
    18661 agaccaataa gaactttaat acctcatctt cctgaaacta aaggtataag tataggatct
    18721 tttctcggag taagtggggt gttgtacact ttccatcatt tggcggttat atttgacgac
    18781 agagaaatgc tagatgaagg cctaaattat gctaaacagt tagaaaaatc tattcctaat
    18841 gatcgtattt atgatttaat tggaggatca gctggggcaa tttttgtgtt aatgaattta
    18901 tatgaacatt taaaagaaga atggctgtta gaattagcaa caaaggctgt tcaacattta
    18961 aaagaacata aaatacctca atctaaagga ttatgttggc caccacctaa taatgaagag
    19021 aaaccttaca taagttattc acacggtaat gcggggatta tagccgcatt aacaaaatat
    19081 tataaataca gtaaagatga ggaaataatt ccattaatat cagaggctct tatatatgaa
    19141 aattcatttt atagtgaatc gaaaaagaat tggtactgtg ttcaaacaga tgattatccg
    19201 actgcctggt gtcatggggc tgcaggtatt cttttaggaa gatctttaat gaagaaaaat
    19261 ggttttactt ctgagacaat taataatgat attactcatg cattagaaac tactctaaat
    19321 cctaacttag gtgcaaatta ttcactatgt catggagatt taggtataat agatatttta
    19381 tttaaattta atgaatactt tagtaatcag attaatgaaa gtattttaga tgatttaatt
    19441 caacaaataa ataaacgaat gttttcgggg gaaaatgaaa ttaaggcaga tttgaattca
    19501 gtgggattaa tgaatggtat tgcaggtatt ggttttgggc tgttacgatt atatgcacct
    19561 aatcaaattc cttctatttt agcattagat tcaccaaaaa ttaagctata aaattattac
    19621 taataataga taagattaat tcacttgaag ttaaatctaa taaagaatgg tttagaataa
    19681 aaatattaat tttttaattt tggcgtttaa ttacttgtga ataaaatggt tttttcttta
    19741 ttgataaaag aaaaattgtg gtcttcaagt cagttttaag aattaatttt aaatttaaaa
    19801 ctgttgaaaa cttactttta agaaagtaag ttgttttata aaaaatttac aaaacaacaa
    19861 ggaatccgta atgggttcct ttttaatata catcaaaagg tacacctttt ga
//
