LOCUS       NZ_CP022685            22098 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8012804
            Orig. end                         :: 8034902
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="37"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22098
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12098](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12098
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            269..643
                     /locus_tag="KY5_RS34910"
                     /old_locus_tag="KY5_6889"
     CDS             269..643
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523706.1"
                     /locus_tag="KY5_RS34910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6889"
                     /product="CU044_2847 family protein"
                     /protein_id="WP_324965837.1"
                     /transl_table=11
                     /translation="MELMRWESDEGPVVVEVDSRDPGFRSVSRRGGDDGIHEVEGRFES
                     ALSNVRGAAMSALRTFRDRALDPDAIELEFGVKLSAVAGAVIAKTAAEGHLTVKLTWSR
                     PQAPGDGTRQDGAGRAVQGE"
     gene            652..2379
                     /locus_tag="KY5_RS34915"
                     /old_locus_tag="KY5_6890"
     CDS             652..2379
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039783.3"
                     /locus_tag="KY5_RS34915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6890"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_159072672.1"
                     /transl_table=11
                     /translation="MHWRARIGTVDGVPRGAGVLVDGARLITCAHVVEGLAEVSVALPG
                     LDDALRGTVAWVGDWRRVGDRGDLAVIALDRPPDATPCAFAPLDVLRPRPGHAAPELRA
                     LGFPFGHDEVGTHVTLRTSADRLLGQEWLEIDVERAHLQCLAEGFSGAAVYDQESHLVV
                     GILTDAVLEDTAAGHIGRMLPLDTIRRHWEELDDLLPLDWLPDAPRRELRALLSDVRID
                     AGNLELIVRRAFPTFRRPLPAFRSVWHAVRHVAEELTGEDRLVRLLDSLRAAGPPGVDI
                     GGWLRRWMPEQCEGGRATGAAIGAAPTGSVMFRAESMTRGAGLDLSVCTVVDGLPVARA
                     GPFRIRPRQLRTKVEALLAEQICRVHEFDWMVEFVVPERLMSEPYEEWQIHEPGAARPR
                     PLRTVPVVVRHMDRLKPLTVSRLTRRRWETVRARGETRPRRVECGLPYGYDEFHDWLDA
                     DDDVCALAYAATPVGDWLAAALDTGVPIMLWRRHDCGDEGHAHCAPDKFLDRLTEAVAA
                     LDPDRLPFEVMRLRKEARSPDKGDAEHCGHRLTLFWDDPERKPDPPLAMRTTGSVERV"
     gene            2372..3436
                     /locus_tag="KY5_RS34920"
                     /old_locus_tag="KY5_6891"
     CDS             2372..3436
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976356.1"
                     /locus_tag="KY5_RS34920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6891"
                     /product="MoxR family ATPase"
                     /protein_id="WP_098245948.1"
                     /transl_table=11
                     /translation="MSETAETAGATATSHWQIYTGSRIPHEGIEALPAPPPWRTFTGGP
                     ALPVPPGDSGNPHAAVSYRPGEDAVRQVNAALYLRRPLLVTGAPGTGKSSLAYAVAHEL
                     GLGKVLHWPITSRVALRDGLYEYDPLTRLYAAERARGDGDAGVGDDIGDYLRLGPLGTA
                     LLPYERPRVLLVDEIDKSDIDLPNDLLTIFEKGSYELVELARRAAPTAKVMTADSTTDR
                     VEIRDGTVTCRAFPLVIMTSNGEREFPPAFLRRCVTVDLKQPASVAELTAIVREHLGPV
                     LCGEDGELPPRTQEIIDRFFERRSGGLLANDQLLNAIYMCHHASFSEEPENVRKLADQV
                     MPYLSGEATRHDDA"
     gene            3426..7766
                     /locus_tag="KY5_RS34925"
                     /old_locus_tag="KY5_6892"
     CDS             3426..7766
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041121.1"
                     /locus_tag="KY5_RS34925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6892"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_098245949.1"
                     /transl_table=11
                     /translation="MTLDRLRDALDALGPPVTPLELAEMLWLAERLPVGEGGGAGVPPS
                     GQYGGDHVDFRQGTFHAPVTGSMAYADVSERPGASDEGAERADPAEPQSEAGPRPAPGR
                     RALHVPHGAPRPGTDADDVLVPAPQALRHELAIQRALRPLKRRVPDRRRRTLDEEATAA
                     RAARHPGLRLWAPVMVPVPDRLLSLALVVDTGPAMTVWRPLARELREAMQRTAAFRDVR
                     VWQLADVGSRVGVRISAEGPALDPAALVDPTGRQIVLVLSDCSGPHWWGGRADPALHLW
                     AGRGPTAILQPLPERLWRRTAAPAVPGRAIASRAGAPNTALRFTPHDGRAVLPAPDAIP
                     VPVLELAPEWLADWAGLVTASGDRGRDTAVTYVSRAHPPHAQPLSSEGDLPVTERILRF
                     QTAASPTAADLAAHVALSVPALPVMRLIQQRVTPGSRPSDLAEVLLSGLLEPVDAERGL
                     YDFVPGARAALLETLPRPESLAVAELLGRLGAEIEARAGSGTRAFRAVVGVAEGAGSRG
                     LGEVGQPFALVSEEALGVLRGRAIRVVERPAEVPDHETVRLPRRDEEPLPPEEAPFEPP
                     GSVTAPTGLSNISAVDPFIGRAHELDGLDRTFTDLHGAERVVLHGVAGVGKTMLARAWA
                     GRWGARDQERPVWWVTADSPASLVKGLSELTDVLQPFVRDARAAGGRWEWALQWLSSHT
                     GWALVLDGVESPDDVRVLLSRLGTRGVVLITSREAEGWPDDVFRLGLGVPALSEAAQMF
                     KVHAGREVAGVVRLCEELGRLPRAVVRAAEAIAGTGVTVDEYLALLARGALEPVEPEGE
                     GSGSAEDLTPTDAIGDAVKESLRGIADPAAVQLLLTLAWWGDSAVPRSLLPTVLDPAYD
                     VTRLLDVLVERGLVHLDASAATVTVPRRFGAIALTPDETLPFRGSGQVDAARHRAVSCL
                     IAAFPAPVDDPEKWPYCRQLVPLVEGLCERARPEDDTALLAQLLTTAGEFLISQWRSES
                     AIGMLDRAMSCRRRLSGRRSPEAVEAMKALAAAFLAARRARDAIDLLQDAMECVAARGR
                     HLDPEALELRARLADAYAAAGDARSAVRQLEDVHTTAAVSLGVEHPETLRLRSRLAGAY
                     VAAGRPGEAVDTYEETLTGCRRVWGGDALETMEVRTGLAFACEAAGATGRAVTELERVV
                     ASVSRVFGAGHPRAVSARLDLAGLYRAAGRVREAVETCAQAYAESLAALGADHPRALDA
                     GERLAEMYLIDGSADRAVDLFGVVWERRRRVLGKTHPDALRAADSLASAYAGIGAVGRQ
                     TALYEGVLADWREPEAAGGGQSVELRELAHAGRARVLGEDHPDTLHALEGLALTRIRTR
                     EPETVSKGFYELSDALTTRWNTQGLFHPDTLRVLGRLVESYLEADHVEQAVQICEEARA
                     SAVRSDGPEAGATVVRHVLAHLASALGPTRSEVEVLQARLARLH"
     gene            complement(7828..8619)
                     /locus_tag="KY5_RS34930"
                     /old_locus_tag="KY5_6893c"
     CDS             complement(7828..8619)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045965.1"
                     /locus_tag="KY5_RS34930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6893c"
                     /product="aldo/keto reductase"
                     /protein_id="WP_098247680.1"
                     /transl_table=11
                     /translation="MPQLGFGVWQVPDDEAEKAVATALDAGYRSIDTAAIYGNEEGTGR
                     AIAASGVARDELFVTTKLWNGEQGYDSTLRAFDASLEKLGLDHVDLYLIHWPLPSKDLY
                     VDTYKAFEKIHADGRAKAIGVSNFLPEHLERLLGETSIVPAVNQIELHPHLQQRASREY
                     HAEQGITTEAWSPLGQGKGLLDVPAIVAIARKHGRTPAQVVLRWHIQLGNVVIPKSVTP
                     SRIKENIDVFGFELDPEDMAAISALNEDRRLGPDPATFDVA"
     misc_feature    8792..8807
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            8945..9085
                     /gene="pqqA"
                     /locus_tag="KY5_RS34935"
                     /old_locus_tag="KY5_6894"
     CDS             8945..9085
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_098245950.1"
                     /locus_tag="KY5_RS34935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6894"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_098245950.1"
                     /transl_table=11
                     /translation="MHSTDQEKSAPESAQRSDAGSAGWQSPEYAIVDTALEVTAYRLAD
                     R"
     gene            9096..10004
                     /locus_tag="KY5_RS34940"
                     /old_locus_tag="KY5_6895"
     CDS             9096..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962380.1"
                     /locus_tag="KY5_RS34940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6895"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_098245951.1"
                     /transl_table=11
                     /translation="MLLQVLGTAAGGGLPQWNCACPGCTGARAHPERRRRHAALAVHAG
                     EGRWYLVNATPDIADQIESVPALNPGTGQDARRTPVAGVVLTDAELDHTLGLARLREAR
                     DGIEVIATAPVRGAVRDGLRLDALLEPYTRVRWRELTAEASLALPGGAGIQLRAVPVSA
                     KRPRYAAGTGADVGTWSVALRIHESATGRTVLYAPALAVWSAAFERAARAADCVLVDGT
                     FWDDDEPVRSGFSARTATAMGHRPIAGRTGTAHRLSQLPARCLYTHLNNTNPLGDPHAE
                     QHKLLAEWGIEVASEGMVIEP"
     gene            10001..10711
                     /gene="pqqC"
                     /locus_tag="KY5_RS34945"
                     /old_locus_tag="KY5_6896"
     CDS             10001..10711
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962381.1"
                     /locus_tag="KY5_RS34945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6896"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_234363009.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.5e-85, bitscore:
                     285.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRHGDELTERLRAVSAGRYHDRHPFNVRMHAGELTREELRRWIA
                     NRFHYQRHIPVKDALILAKFDDPAPRRGWLRRIRDHDGEREGEGGIERWLRLGEAAGLK
                     REQLLDSSRVLPGVRLAVDGYVNFCRLRPVLDAVAASLTELSAPDLMRTRIAAFERHYP
                     WIDAEGLAYFRTRVDQGARDGQEALALVLEWARTPEEQDRAVAALAFKCDVLWSLLDAV
                     ERGNAVGPLSGGAA"
     gene            10708..10986
                     /gene="pqqD"
                     /locus_tag="KY5_RS42795"
                     /old_locus_tag="KY5_6897"
     CDS             10708..10986
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433952.1"
                     /locus_tag="KY5_RS42795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6897"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_234363010.1"
                     /sec_met_domain="PqqD_RRE (E-value: 5.8e-18, bitscore:
                     63.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-09, bitscore: 35.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHDVVRGDWRPELSRSVLLRHDRVRDVDLLVLPERVVVLRGAA
                     GSIVALCDGARDVVAIVAELARRHPDAPVAAEVPAFLKQLRAEGWLR"
     aSDomain        10726..10980
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KY5_RS42795_PqqD_RRE.1"
                     /evalue="2.00E-20"
                     /identifier="RREFam006.1"
                     /label="KY5_RS42795"
                     /locus_tag="KY5_RS42795"
                     /protein_end="91"
                     /protein_start="6"
                     /score="63.3"
                     /tool="antismash"
                     /translation="VRGDWRPELSRSVLLRHDRVRDVDLLVLPERVVVLRGAAGSIVAL
                     CDGARDVVAIVAELARRHPDAPVAAEVPAFLKQLRAEGWL"
     gene            10983..12098
                     /gene="pqqE"
                     /locus_tag="KY5_RS34950"
                     /old_locus_tag="KY5_6898"
     CDS             10983..12098
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669244.1"
                     /locus_tag="KY5_RS34950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6898"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_234363011.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-19, bitscore: 70.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.1e-05, bitscore: 22.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.9e-09, bitscore:
                     35.7, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPDPPWALLAELTHACPLRCSYCSNPVELAAKADELTAIEWGD
                     VFRQAAALGVVQSHLSGGEPLLRRDLTEIVAAATAAEIHTQLVTSGVGLHRARLDALVG
                     AGLHSVQLSVQHADPAAALRIAGARASAAKERAAGLIRAAGLPLGLNAVLHRANLDALD
                     ALVELGLDWGADRLELANTQFYGWALRNRDALLPGRAQVARARERVERWRQRLEGRMEI
                     VWVAPDYVDGVAKPCMGGWGALSLTVAPDGRALPCPASADLLGAAAPNVRDRQLSWIWR
                     ESEAFTRYRGEAWMSDTCRGCELRAVDFGGCRCQAYALTGDAARTDPACHRSPDHAMVR
                     ALVDGAGHAADAADAPPDYVYRTHTAGPALT"
     misc_feature    complement(12141..12155)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.28"
                     /tool="antismash"
     misc_feature    12153..12167
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.53"
                     /tool="antismash"
     misc_feature    complement(12174..12192)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.1"
                     /tool="antismash"
     gene            12189..13229
                     /locus_tag="KY5_RS34955"
                     /old_locus_tag="KY5_6899"
     CDS             12189..13229
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076325.1"
                     /locus_tag="KY5_RS34955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6899"
                     /product="chitinase"
                     /protein_id="WP_234363012.1"
                     /transl_table=11
                     /translation="MRLHAPRSRTRVRPRTTTAALAAVTALSGAAALTLAGEPSAQASP
                     APAARASGTIHAAPYEYLGWGNPQKPTDVMAATGVKWFTLAFILSDGGCDPAWDGSRPL
                     KGGSDEAAIKSIRGAGGDIVVSVGGWSGAKLGEKCAGAAALAGAYQKVIDAYKLKVFDI
                     DIEDTEFSNATVRQRVVDALKIVKAKNPGIVTYVTMGTTPNGPDATGKDLIKRGAAAGL
                     ANDAWVIMPFDFDGHSGTMGQASVSAMEGLKKAVKSAYGYSDADAYRHIGVSSMNGKTD
                     VAGETVTTADFKTILAYAKQHHIARYSFWSVNRDRACGSGGDADACSGVAQSPYDFTKI
                     VAQYGG"
     gene            13231..14343
                     /locus_tag="KY5_RS34960"
                     /old_locus_tag="KY5_6900"
     CDS             13231..14343
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645350.1"
                     /locus_tag="KY5_RS34960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6900"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_098245953.1"
                     /transl_table=11
                     /translation="MELGKQRAVLLATAVVLVAGAVTTATAGASTTATAGASTTAAAGE
                     PGTPVTLSTGWTIPWGTSWLPDGSGALVTERDDFGVWRISKDGKERKRVGTVPESQTTG
                     GEGGLMGLAVDPDWATNHYVYVMHTSSEGNRIARMTYDGTTVSGYKVLLKGIKKNKYHN
                     GGRLAFGPDGYLYATTGDAQDKPLAQDKNSLNGKILRLTTDGKPAPGNPFGNYAYSLGH
                     RNPQGIAFDAQGRLWEAELGDSKKDELNLIKAGKNYGWPTCEGTCDVAGMTNPKRTWGV
                     AEASPSGVAVVDGAVYMAALKGKRLWRIPTNADNENVGTPKAYYIGEYGRLRSVTAVPG
                     AKELWLSTTNADNNGGQPEGSDTIFRVPIG"
     gene            complement(14357..15148)
                     /locus_tag="KY5_RS42995"
                     /old_locus_tag="KY5_6901c"
     CDS             complement(14357..15148)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737799.1"
                     /locus_tag="KY5_RS42995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6901c"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098245954.1"
                     /transl_table=11
                     /translation="MREREKRQYVLEASGVGVRFGGIHALRGVDLAVRPGEVCGLIGPN
                     GAGKTTLFDVLSGIRRPDDGSVLLDGADVTRRSPVWRARHGMRRTFQRQQLFGQLTVAD
                     NLVVAQEWRGGGGGFAADLVAAPTRRTYERTRRERADAVLRECGLDALAGEYAGALPVG
                     QARMVELARAVADPPRVLLLDEPASGMTGDERGQLAAVVRHLADEEGCAVLLVEHNVAF
                     VMELCARVVVLDLGRVLAHGTAAEVRADPEVRDAYLGAAAP"
     gene            complement(15145..17856)
                     /locus_tag="KY5_RS34970"
                     /old_locus_tag="KY5_6902c"
     CDS             complement(15145..17856)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534306.1"
                     /locus_tag="KY5_RS34970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6902c"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_098245955.1"
                     /transl_table=11
                     /translation="MSDLLGFVLSGLVSGALYALLATGLVLSYSASGLFNFAHGATAYL
                     CALAFYELRSGFGWPAVPTALLLVLVVAPGLGWGLDRLMFRKLARVGETAQIVATIGLL
                     VALPALGLWVVELLEGAGAPVKPAENQFGLPGVGPSPAKSWQLTDGVGIDSDQLITWVA
                     TALVAVALWVLMRHTPLGLRLRAAVDNRSLVELRGMSADRLSSVAWMLSSGLAGLAGVL
                     ATPLLGLSSHDFTLFLFVSATAAVLGRFLSVPLAFAGGLGLGVLQNLVAGYADFAERIT
                     GFRTAVPFLILFAGLLVMTRRSRTAGTAAVDAPPIDYLAGRSWTRRWGPWAVAAALLAL
                     SFYTVTTPFWSGVLAQGLAISLVFVSFTVVTGLGAMVSLAQATFVTGAALVAGLLMSHG
                     WPFAGAALVGTCAAALLGALVALPALRLGGRSLALATLALAFLADQVLFQLGWLRNGDT
                     GWEIPRPAVGPVDLSDDRAMGVAMVVLVTVAVAALAALRNSPSGRTMLAVRSAPAAAMA
                     SGVSVVRTKLLLFTLSAGLAGFGGVMYASFNTRITATDFTAMTGLIWLAVAVAAGVRRA
                     QFAVVAGLVFAIVPHLVSDYVTESVHVPVVLFGLAGLALANDPDGYCAAVSVRMHRRRV
                     QRAPGGGRRTWGSAPDPAPQTPEGLNHALALHGIHAGYDGAPVLHGVDLTVRPGEIVAL
                     LGPNGAGKSTTCRVAAGLIRPVEGHVYVAGRDVTREGAVLRSRAGVLLAPEGRGIFPSL
                     TIEENLALHLKDKDERDAVYERFAGLAARRKVVAGSLSGGEQQMLALAPLLQHPPTVLV
                     ADEPSLGLAPRVVEEVFRLLVELRDQGTALLLVEEKAAEILGVADTVAYLAQGRVSWCG
                     PRSEVRADRLTEAYLGMAAGEGQRTTKGVARS"
     gene            complement(17912..19180)
                     /locus_tag="KY5_RS34975"
                     /old_locus_tag="KY5_6903c"
     CDS             complement(17912..19180)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031791.1"
                     /locus_tag="KY5_RS34975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6903c"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_098245956.1"
                     /transl_table=11
                     /translation="MSRSISAITATVAALLLATACNSASNSGGSEGAGGGKGGGSVRGV
                     TDDSIKVGGIVSMTTASGYSKKDTDLGAKARFDRANAEGGVHGRKIDYLGAEDDGQDPG
                     KNLAAARKLVQRDKVFAISPMSSVTFSGADFLQKQRVPTFGWGTIPPFCGPSYLYGFGG
                     CMVPMPGGTITQSWPEGLKKVMGGAEGKTVAILANDNDAGTFAIRTYQQSFAAAGYEVT
                     YAKSTVPATSVPSDWSAYTKEILRSNGGKAPDAVVSVMQTPYNIGLFTAVKRTGFKGVL
                     TDPTDYDPGLLAKSATKKALDGVHVLLTFQPFEQDSADMRRFKKDIAKAAGKKVPLNMH
                     MMTGYMSADLFLAIAEKAGKDLDVESFQRAADGFSDTDTMVGDRRLPKGHKESFGCGAL
                     VQLKGSAYTVSSPFTCYEPIPFT"
     gene            complement(19297..21096)
                     /locus_tag="KY5_RS34980"
                     /old_locus_tag="KY5_6904c"
     CDS             complement(19297..21096)
                     /NRPS_PKS="Domain: AMP-binding (14-468). E-value: 1.2e-90.
                     Score: 296.0. Matches aSDomain:
                     nrpspksdomains_KY5_RS34980_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676059.1"
                     /locus_tag="KY5_RS34980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6904c"
                     /product="AMP-dependent synthetase/ligase"
                     /protein_id="WP_199843681.1"
                     /sec_met_domain="AMP-binding (E-value: 7.8e-86, bitscore:
                     287.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASAPLVGGLADAVFDHAAEDPLRIALGRKTDGQWHDVTSGEFRD
                     EVLALAKGLIAQGVRFGDRVAIMSRTRYEWTLFDFALWAIGAQVVPIYPTSSAEQVFWM
                     LHDAQVSAAMVEHEDHAMTIGSVIDRLPQLRRLWQLDADAVGELNGAGRDIDDDVVHRH
                     RRAVTPDSIATIIYTSGTTGRPKGCLISHANFMFEADVMVARWEPVFHSKRGDEATTLL
                     FLPLAHVFGRMVQIAAVRGRVKMGHQPNLNAAALLPDLAAFRPSFILAVPYIFEKVFNA
                     ARRKAEAAGKAGAFDKAVECAVRYAEAMEARAFGTGSGPSASLRMQHQVFDKLVYSKVR
                     EAMGGRVRHAMSGGSGMDRRLGLFFAGAGVTIYEGYGLTESTAAATANPPERTRYGTVG
                     LAIPGTTVHIADDGEVWLHGGNVFQGYLGDHKATAASLHDGWLATGDLGSLDEDGYLTI
                     TGRKKEILVTSGGKSVSPAQLEERVRDHPLVAQCIVVGNDRPYIAALVTLDAEAVEHWL
                     TMRRKPLLSPGELVRDPDLETEVRRAVVAANTLVSQAESIRTFRILAHQFSEEHGLLTP
                     SLKLKRKAIEQAYLTEVEALYKT"
     aSDomain        complement(19693..21054)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS34980_AMP-binding.1"
                     /evalue="1.20E-90"
                     /label="KY5_RS34980_AMP-binding.1"
                     /locus_tag="KY5_RS34980"
                     /protein_end="468"
                     /protein_start="14"
                     /score="296.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FDHAAEDPLRIALGRKTDGQWHDVTSGEFRDEVLALAKGLIAQGV
                     RFGDRVAIMSRTRYEWTLFDFALWAIGAQVVPIYPTSSAEQVFWMLHDAQVSAAMVEHE
                     DHAMTIGSVIDRLPQLRRLWQLDADAVGELNGAGRDIDDDVVHRHRRAVTPDSIATIIY
                     TSGTTGRPKGCLISHANFMFEADVMVARWEPVFHSKRGDEATTLLFLPLAHVFGRMVQI
                     AAVRGRVKMGHQPNLNAAALLPDLAAFRPSFILAVPYIFEKVFNAARRKAEAAGKAGAF
                     DKAVECAVRYAEAMEARAFGTGSGPSASLRMQHQVFDKLVYSKVREAMGGRVRHAMSGG
                     SGMDRRLGLFFAGAGVTIYEGYGLTESTAAATANPPERTRYGTVGLAIPGTTVHIADDG
                     EVWLHGGNVFQGYLGDHKATAASLHDGWLATGDLGSLDEDGYLTITGRKKEILVT"
     CDS_motif       complement(19789..19860)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KY5_RS34980_0002"
                     /evalue="7.70E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="KY5_RS34980"
                     /protein_end="436"
                     /protein_start="412"
                     /score="18.3"
                     /tool="antismash"
                     /translation="GEVWLHGGNVFQGYLGDHKATAAS"
     CDS_motif       complement(20521..20580)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KY5_RS34980_0001"
                     /evalue="7.70E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="KY5_RS34980"
                     /protein_end="192"
                     /protein_start="172"
                     /score="27.7"
                     /tool="antismash"
                     /translation="ATIIYTSGTTGRPKGCLISH"
     misc_feature    21307..21325
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.27"
                     /tool="antismash"
     gene            21399..22010
                     /locus_tag="KY5_RS34985"
                     /old_locus_tag="KY5_6905"
     CDS             21399..22010
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987222.1"
                     /locus_tag="KY5_RS34985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6905"
                     /product="hypothetical protein"
                     /protein_id="WP_234363014.1"
                     /transl_table=11
                     /translation="MPAHHPPRPARRAAATRGRRITGVCAVALPTALLALQLGLGPAAQ
                     AHEGVGAGPRAASSVAAPDKATISEGQVEEVAPGGVITYPSVTSCLTVTVRLREGGLVG
                     AHASLFQVPGELRSDQILAALKGRVGDRAVASVEVRGAVGAWHPSYFAKAIESYGEGEQ
                     VPVPTVPDPDGIARAVSEGLGTAPGLVSVEDVPDGDQVVS"
     misc_feature    complement(22060..22073)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.41"
                     /tool="antismash"
ORIGIN
        1 ccgccgcgag atgcacgagg aactcctcgg cgccgacgag ctggccacca tcgaccgtct
       61 cctggacccg tcggacccgg gcggcctcct cctcaggccc gacgcgttcc tgctgctcgc
      121 gcagacggtg catgtggcgg tcaaggaccg ggagcagggc tagccgggca cgcgtcccgc
      181 atcccacgta ttcgcccaac tgccggtgtg tggactcctg ttgacgtaac gtcgggaggt
      241 ctccggcagg aaggggtgcg gtcgcgtgat ggagctgatg cggtgggagt ccgacgaagg
      301 acccgtagtg gtcgaagtgg actccaggga ccccgggttc aggtccgtgt cgcggcgtgg
      361 cggggacgac gggatccatg aggtcgaggg gcgcttcgag tcggcgttga gcaatgtgcg
      421 cggggccgcg atgtccgcgc tgcggacctt ccgggaccgg gcactcgacc ccgatgccat
      481 cgagttggaa ttcggggtca agctcagcgc cgtggcgggt gccgtcatcg ccaagaccgc
      541 cgccgaggga cacctgaccg tcaagctcac ctggtccagg ccgcaggccc cgggagacgg
      601 cacccgacag gacggcgccg gacgggcggt ccaaggcgaa taatggcggg catgcactgg
      661 cgtgcccgga tcggcacggt cgacggcgtt cccagaggag cgggcgtgct ggtcgacggt
      721 gcgcggctga tcacctgcgc ccacgtcgtc gagggcctgg ccgaggtctc cgtggcgctg
      781 ccgggactcg acgacgcgct gcgcgggacc gtggcgtggg tcggggactg gcggcgcgtg
      841 ggggatcgcg gggacctggc cgtgatcgcg ctcgaccggc cgcccgacgc gacgccgtgc
      901 gcgttcgccc cgctcgacgt cctgcggccg cgcccggggc acgccgcccc cgaactgcgc
      961 gcgctcggct tcccgttcgg ccacgacgag gtggggacgc acgtcacgct gcgcaccagc
     1021 gcggaccggc tgctaggcca ggagtggctg gagatcgacg tggagcgggc ccatctccag
     1081 tgcctcgccg aggggttcag cggcgccgcc gtctacgacc aggagagcca tctcgtcgtc
     1141 ggcatcctca ccgacgccgt gctcgaggac accgccgccg gtcacatcgg acggatgctg
     1201 cccctcgaca ccatccgccg ccactgggag gagctggacg acctcctgcc gctcgactgg
     1261 ctgccggacg cgccgcgccg cgaactgcgc gcgctgctga gcgacgtacg gatcgacgcg
     1321 gggaacctgg agctgatcgt ccggcgggcc tttcccacct tccgccgccc gctgcccgcc
     1381 ttccggtccg tctggcacgc ggtccgtcac gtcgccgagg aactgaccgg cgaggaccgg
     1441 ctcgtgcggc tcctcgactc gctgcgtgcg gcggggccgc ccggggtgga catcggcggg
     1501 tggctgcggc ggtggatgcc cgagcagtgc gaagggggcc gggcgaccgg cgcggcgatc
     1561 ggcgccgcac ccaccggttc cgtcatgttc cgcgccgagt cgatgacccg gggcgccgga
     1621 ctcgacctct ccgtctgcac cgtggtcgac ggcctgcccg tcgccagggc ggggcccttc
     1681 aggatccggc cacgccaact gcggacgaag gtggaggcgc tgctcgccga acagatctgc
     1741 cgcgtccacg agttcgactg gatggtggag ttcgtggtgc ccgaacggct gatgagcgag
     1801 ccgtacgagg agtggcagat ccacgagccg ggcgccgcgc ggccccggcc gctgcgcacg
     1861 gtgccggtcg tggtccggca catggaccgg ctgaagccgc tcaccgtctc gcggctcacc
     1921 cgcaggcgct gggagacggt gcgggcccgc ggcgagacca ggccgcggcg cgtggagtgc
     1981 ggactgccct acggctacga cgagttccac gactggctgg acgccgacga cgacgtgtgc
     2041 gccctcgcgt acgccgcgac acccgtgggc gactggctcg cggccgccct cgacaccggc
     2101 gtgccgatca tgctgtggcg gcgccacgac tgcggcgacg agggccacgc ccactgcgcg
     2161 cccgacaagt tcctcgaccg gctcacggag gcggtcgccg cactcgaccc ggaccggctg
     2221 ccgttcgagg tgatgcggct gcgcaaggag gcgcgctccc ccgacaaggg ggacgccgag
     2281 cactgcgggc accggctgac cctgttctgg gacgacccgg agcgcaagcc cgacccacca
     2341 ctggccatgc ggaccacagg gagcgtggag cgtgtctgag acggctgaga cggccggggc
     2401 gacggcgacg tcccactggc agatctacac cggaagccgg atcccgcacg aaggaatcga
     2461 ggcactcccg gccccgcccc cgtggcgcac cttcaccggc ggccccgccc tgcccgtccc
     2521 gcccggcgac tccggcaacc cgcacgcggc cgtcagctac cggccgggcg aggacgcggt
     2581 ccggcaggtc aacgccgcgc tgtacctgcg caggccgctc ctggtgaccg gcgcacccgg
     2641 caccggcaag tcctccctcg cgtacgcggt ggcgcacgaa ctgggcctcg gcaaggtcct
     2701 gcactggccg atcaccagcc gcgtcgccct gcgcgacggc ctttacgaat acgacccgct
     2761 gacccgcctg tacgccgccg aacgcgcccg gggcgacggt gacgcggggg tcggcgacga
     2821 catcggcgac tatctgcgcc tcggccccct cggcaccgcg ctgctcccct acgagcggcc
     2881 ccgcgtgctg ctcgtcgacg agatcgacaa gagcgacatc gacctgccca acgacctcct
     2941 caccatcttc gagaagggct cctacgaact cgtcgagctg gcccgccgcg ccgcgcccac
     3001 cgccaaggtg atgacggccg acagcaccac cgaccgcgtg gagatccgcg acggcaccgt
     3061 cacctgccgt gccttccccc tcgtcatcat gaccagcaac ggcgagcgcg agttcccgcc
     3121 cgcgttcctg cggcgctgcg tgaccgtgga cctgaaacag cccgcgagcg tggcggagct
     3181 gaccgcgatc gtccgcgagc acctcggccc ggtgctgtgc ggcgaggacg gcgaactccc
     3241 gccgcgtaca caggaaatca tcgaccgctt cttcgaacgg cgcagcggcg gactcctcgc
     3301 caacgaccag ctcctcaacg ccatctacat gtgccaccac gcgtcgttca gcgaagagcc
     3361 cgagaacgtc aggaagttgg cggaccaggt gatgccgtac ctgagcggcg aggcgacccg
     3421 gcacgatgac gcttgaccgg ctcagggacg cgctggacgc cctcggcccg ccggtcaccc
     3481 cgctggagct ggcggagatg ctgtggctgg cggagcggct gcccgtgggg gagggcggtg
     3541 gtgccggggt tccgccgtcg ggccagtacg gcggtgacca cgtggacttc cggcagggta
     3601 cgttccacgc tccggtgacg ggctcgatgg cctacgccga cgtgagcgag cgccccggag
     3661 cgagcgacga gggtgcggag cgcgccgacc cggcggagcc gcagagcgag gccggtccgc
     3721 gccccgcccc cgggcgccgg gccctgcacg tcccgcacgg cgccccgcgc cccggcaccg
     3781 acgccgacga cgtcctcgtc cccgccccgc aggccctgcg ccacgaactc gccatccagc
     3841 gcgccctgcg cccgctcaag cgccgcgtcc ccgaccggcg ccgccgcacc ctggacgagg
     3901 aggccaccgc cgcacgcgcc gcgcgccacc cgggcctgcg tctctgggcc ccggtcatgg
     3961 tcccggtccc cgaccggctc ctgagcctcg ccctggtcgt cgacacgggc cccgcgatga
     4021 cggtgtggcg tccgctcgcc cgcgaactgc gcgaggcgat gcagcgcacc gccgccttcc
     4081 gcgacgtacg cgtgtggcag ctggcggacg tcgggtcgcg cgtcggcgtc cggatctccg
     4141 ccgaggggcc cgcccttgac ccggcggcgc tcgtcgaccc gacggggcgt cagatcgtcc
     4201 tggtgctcag cgactgctcg ggcccgcact ggtggggcgg ccgggcggac cccgcgctgc
     4261 acctgtgggc ggggcgcggc cccaccgcga tcctccagcc gctgcccgaa cgcctctggc
     4321 gcaggaccgc ggcccccgcg gtcccgggcc gtgccatcgc ctcccgcgcg ggcgccccca
     4381 acaccgcact gcgcttcacc ccgcacgacg gccgcgccgt cctgcccgcg cccgacgcga
     4441 tccccgtgcc ggtcctcgaa ctcgcccccg agtggctcgc tgactgggcg ggcctggtga
     4501 ccgcgtccgg cgaccggggc agggacacgg ccgtgacgta cgtcagccgc gcccacccgc
     4561 cgcacgccca acccctgtcc agcgagggtg acttgccggt caccgagcgg atcctgcgct
     4621 tccagacggc ggcatccccc acggcggcgg acctggccgc ccacgtcgcg ctctccgtcc
     4681 ccgcactgcc ggtgatgcgg ctcatccagc aacgggtgac gcccggttcg cgccccagcg
     4741 acctggcgga ggtcctcctg agcggcctcc tggaaccggt cgacgcggaa cgcggcctgt
     4801 acgacttcgt gccgggagcc agggccgcac tcctggagac cctgccccgc cccgagtcgc
     4861 tcgcggtcgc cgagctgctc ggccgcctcg gcgcggagat cgaggcgagg gcggggtcgg
     4921 ggacgcgggc gttccgggcg gtcgtggggg tagcggaggg agcggggagt cgggggctcg
     4981 gggaggtggg gcagccgttc gcgctggtca gcgaggaggc gttgggggtg ctcagagggc
     5041 gggcgatacg ggtggtggag cggcccgcgg aggtcccgga tcacgagacg gtgagattgc
     5101 ccaggaggga tgaggagccg cttcccccgg aggaggcgcc attcgaaccg cccggatcgg
     5161 tgacggcccc gaccgggctc tccaacatct ccgccgtgga cccgttcatc ggcagggcgc
     5221 atgaactcga cggcctggac aggacgttca ccgacctcca cggggcggag cgggtcgtcc
     5281 tgcacggcgt ggcgggcgtg ggcaagacca tgctggcgag ggcgtgggcg gggcggtggg
     5341 gcgctcggga ccaggagcgc ccggtgtggt gggtcaccgc ggactcgccc gcgtccctgg
     5401 tcaaagggct ctcggagctg accgatgtac tccagccgtt cgtgagggac gcgcgcgcgg
     5461 cgggcggccg atgggagtgg gctcttcagt ggctgagctc gcacaccggc tgggcgctcg
     5521 tgctcgacgg cgtcgagagc cctgacgacg tgcgtgtgct gctgtcgcgc ctgggcaccc
     5581 gcggcgtcgt cctgatcacc agccgggagg cggagggctg gccggacgac gtcttccggc
     5641 tcggtctcgg cgtgcccgcg ctgtcggaag cggcccagat gttcaaggtc cacgcgggcc
     5701 gggaggtcgc cggggtcgtg cggctgtgcg aggagctggg gcggctgccg agggcggtgg
     5761 tgcgggcggc cgaggcgatc gccgggacgg gggtgacggt ggacgagtac ctcgccctcc
     5821 tcgcgcgggg agcgctcgaa ccggtggaac ccgaggggga gggctcgggg tcggcggagg
     5881 acctgacgcc gacggacgcg atcggggacg cggtcaagga gtcactgcgc ggcatcgccg
     5941 acccggcggc cgttcaactc ctgctgaccc ttgcctggtg gggcgacagc gccgttcctc
     6001 gcagcctgct cccgaccgtt ctggacccgg cgtacgacgt gacgcgcctc ctggacgttc
     6061 tggtggagcg cggcctggtg catcttgacg cgtcggcggc cacggtcacg gttccgaggc
     6121 gcttcggagc catcgccctc acgccggacg agactctgcc cttccgtggc tccggccagg
     6181 tcgacgcggc ccggcaccgg gccgtcagct gcctgatcgc cgcgttccct gcgcctgtgg
     6241 acgacccgga gaaatggccg tactgccgtc agctcgtgcc gctcgtcgag gggttgtgcg
     6301 agagggccag gcccgaggac gacaccgcct tgctggctca actgctcacc acggcggggg
     6361 aattcctcat cagccagtgg cggtcggagt cggccatcgg catgttggac cgggcgatgt
     6421 cgtgcaggcg acggctttcg gggcgccggt cgccggaggc ggtggaggcc atgaaggccc
     6481 tggcggcagc cttcctggcc gcgcggcgcg cgagggacgc gatcgacctc ctccaggacg
     6541 ccatggagtg tgtggccgcc agggggaggc acctggaccc cgaagcgctc gagctgcgcg
     6601 cccggctcgc cgacgcctac gccgcggcgg gtgatgcgcg gtcggccgtg cggcaactgg
     6661 aggacgtcca cacgacggcg gccgtctccc tgggagtcga gcatcccgag accttgcggc
     6721 tgcggtcccg gctcgcgggc gcgtacgtgg cggcggggcg tccgggcgag gccgtggaca
     6781 cgtacgagga gacgctgacc ggctgccgca gggtctgggg cggcgatgcc ctggagacga
     6841 tggaggtgcg cacgggcctg gccttcgcgt gtgaggcggc gggcgccacg ggccgggcgg
     6901 tgaccgaact ggagcgggtg gtggcgagtg tgtcccgggt gttcggtgcc gggcacccgc
     6961 gggcggtttc cgcccggttg gacctggccg gtctctacag ggccgcgggc agggtgcggg
     7021 aggccgtcga gacgtgcgcg caggcgtacg ccgaaagcct cgcggcgctg ggggcggatc
     7081 atccgcgggc tctggacgcg ggggagcggc tggccgagat gtacctcatc gacgggagcg
     7141 cggaccgggc cgtcgacctg ttcggagtgg tgtgggaaag gcggagaagg gtcctcggaa
     7201 agactcaccc ggacgcgctc cgggccgcgg actccctcgc gtccgcctat gcgggcatcg
     7261 gggccgtggg caggcaaacc gccctgtacg aaggggtctt ggcggactgg cgcgaaccgg
     7321 aggcggcggg cgggggccag tccgtggagc tgcgggagct ggcccacgcc gggcgggcgc
     7381 gggtgttggg tgaggaccac cccgacaccc tgcacgcgct ggaggggctc gcgctcaccc
     7441 ggatccgcac ccgggagccg gagacggtgt cgaagggctt ctacgagctc agtgacgcgc
     7501 tgacgacgcg gtggaacact caggggctct tccaccccga cactcttcgc gtgctcggca
     7561 gactcgtgga gtcctacctg gaagcagatc atgtcgagca ggccgtccag atctgcgagg
     7621 aggctcgcgc gagtgccgtc aggagtgacg gtccggaggc cggggcgacc gtggtgcggc
     7681 acgtcctcgc ccacctcgcg tccgccctcg gccccacccg ctcggaagtc gaagtcctgc
     7741 aagcgcgcct ggcccgcttg cactgacccg aagggccacc gcaagcgagc cagtacgtct
     7801 tgcctacgtc ctagaggcag gcgcccgtca ggccacgtcg aacgtcgccg ggtcggggcc
     7861 gagccgccgg tcctcgttca gcgccgagat cgccgccatg tcctcggggt cgagctcgaa
     7921 gccgaagacg tcgatgttct ccttgatccg cgacggggtc acggacttgg ggatcaccac
     7981 gttgcccagc tggatgtgcc agcgcagcac gacctgggcg ggagtccgcc cgtgcttgcg
     8041 cgcgatcgcg acgatcgcgg ggacatcgag gaggcccttg ccctggccga gcggcgacca
     8101 cgcctcggtg gtgatgccct gctccgcgtg gtactcgcgg gaggcgcgct gctggaggtg
     8161 cgggtgcagc tcgatctggt tgacggccgg gacgatcgac gtctcgccga gcagccgctc
     8221 caggtgctcg ggcaggaagt tcgagacgcc gatggccttg gcgcggccgt cggcgtggat
     8281 cttctcgaac gccttgtacg tgtcgacgta caggtccttc gagggcagcg gccagtggat
     8341 caggtacagg tccacgtggt cgaggccgag cttctccagc gacgcgtcga aggcgcggag
     8401 ggtggagtcg taaccctgct cgccgttcca gagcttcgtc gtgacgaaga gctcgtcgcg
     8461 ggcgacgccg gaggcggcga tggccctgcc ggtgccctct tcgttgccgt agatggccgc
     8521 ggtgtcgatg ctgcggtacc cggcatccag cgccgtcgcg acggccttct cggcctcgtc
     8581 gtccggcacc tgccagacgc cgaaaccgag ctggggcatc tcgacgccgt tgttcaggat
     8641 gatcgggggg gtcttgctca cgagcttcga tccttaagtc gtcgggtggt actcccatgg
     8701 tcaacgatca gaggcggtgt cgcattcctg gaggtgtgag ggccgcgtga gagccgggtg
     8761 atggccggat atcgaagggg tgccggagcg gatcggtccg gaccattgac ggtgctccgt
     8821 catgccgcga ccctgttgca cgtcactgaa cgccggacac tcatgtgaac gcacctctcg
     8881 cctgcgccgc ccgcgtccca gtggcttgct cctgaaaccc cacctcttca ggaaaggcag
     8941 cgacatgcac agcaccgacc aggagaagtc cgcaccggag tccgcccagc ggtccgacgc
     9001 cgggagcgcg ggctggcaga gtcccgagta cgcgatcgtc gacaccgccc tcgaagtcac
     9061 cgcctaccgc ctcgccgacc ggtagacccg ccgccatgct gctgcaggtg ctcggcaccg
     9121 cggcgggcgg cgggctgccc cagtggaact gcgcgtgccc cgggtgcacc ggggcgcgcg
     9181 cccacccgga gcgccgccgt cggcacgccg cactcgccgt ccacgcgggg gaggggcgct
     9241 ggtacctcgt caacgccacc cccgacatcg ccgaccagat cgagtcggtc cccgccctga
     9301 accccggcac gggccaggac gcgcggcgca cccccgtcgc cggggtcgtc ctcaccgacg
     9361 ccgagctcga ccacaccctg ggcctcgccc ggctgcgcga ggcccgcgac ggcatcgagg
     9421 tcatcgccac ggcacccgtg cgcggcgcgg tgcgcgacgg gctgcgactc gacgccctcc
     9481 tggagcccta cacgcgcgtg cgctggcgcg agctgaccgc cgaggcgagc ctggcgctcc
     9541 ccggcggcgc ggggatccag ctgcgcgccg taccggtttc ggccaagcgt ccccggtacg
     9601 ccgccggcac cggcgccgac gtgggcacct ggtccgtcgc cctgcgcatc cacgagtccg
     9661 cgaccggcag gaccgtgctc tacgcccccg ccctcgcggt gtggagcgcc gcgttcgagc
     9721 gggcggcgcg ggccgccgac tgcgtgctcg tcgacggcac cttctgggac gacgacgagc
     9781 ccgtacggtc cggcttctcg gcccgcaccg ccaccgccat ggggcaccgc ccgatcgcgg
     9841 gacgcaccgg cacggcccac cgcctctcgc agctccccgc gcgctgtctc tacacccacc
     9901 tcaacaacac caaccccctc ggggacccgc acgccgagca gcacaagctc ctcgccgagt
     9961 ggggcatcga agtggcatcg gaggggatgg tgatcgagcc gtgacacgtc acggggacga
    10021 gctgacggaa cggctgcgcg ccgtctccgc agggcgctac cacgaccggc accccttcaa
    10081 cgtccgcatg cacgcgggcg agctcacgcg cgaggaactg cgccgctgga tcgccaaccg
    10141 gttccactac cagcggcaca tccccgtcaa ggacgccctg atcctcgcga agttcgacga
    10201 cccggcgccg cgccgcggct ggctgcgcag gatcagggac cacgacgggg agcgcgaggg
    10261 cgagggcggc atcgagcggt ggctgcggct cggtgaggcg gccggactga agcgggaaca
    10321 actcctggac tcctcaaggg tgttgcccgg cgtgcggctc gcggtcgacg ggtacgtcaa
    10381 cttctgtcgg ctcaggcccg tgctggacgc cgtggccgcc tccctcacgg agttgtccgc
    10441 gcccgatctg atgcgcacca ggatcgccgc cttcgaacgg cactacccgt ggatcgacgc
    10501 ggaagggctc gcctacttcc gtacgcgcgt cgatcagggc gctcgcgacg gacaggaggc
    10561 gctcgccctc gtcctggagt gggcccgcac ccccgaggag caggatcggg ccgtcgccgc
    10621 cctcgcgttc aagtgcgacg tcctgtggtc actgctcgat gccgtcgagc gagggaacgc
    10681 cgtcgggccg ctgtccggag gtgccgcatg agcacccacg acgtcgtacg cggcgactgg
    10741 cgtcccgagc tctcccgctc cgtgctgctc cggcacgacc gggtgcgcga cgtggacctc
    10801 ctcgtcctgc ccgagcgcgt cgtcgtcctg cggggcgccg ccgggagcat cgtggccctg
    10861 tgcgacggcg cacgcgatgt cgtcgccatc gtcgcggaac tggcgcgccg ccaccccgac
    10921 gcgccggtcg ccgccgaagt ccccgcgttc ctgaagcagt tgcgcgccga agggtggctg
    10981 cggtgaccga acccgacccg ccctgggcgc tcctcgccga gctcacccac gcctgcccgc
    11041 tgcgctgctc gtactgttcc aaccccgtcg aactagcggc caaggcagac gagttgacgg
    11101 ccatcgagtg gggtgacgtc ttccgtcagg ccgccgcgct cggtgtcgtg cagagccatc
    11161 tctcgggcgg ggagcccctg ctgcgccgcg acctcaccga gatcgtcgcg gccgccaccg
    11221 ccgcggagat ccacacccag ctcgtgacca gcggcgtcgg tctgcaccgg gcccgcctcg
    11281 acgcgctggt cggtgccggg ctgcacagcg tccaactgtc cgtgcagcac gcggatccgg
    11341 ccgccgccct gcgcatcgcg ggcgcacgcg cctccgcggc gaaggagcgg gccgccgggc
    11401 tgatcagggc cgccggtctg ccgctcggcc tcaacgccgt gctgcaccgc gccaacctcg
    11461 acgcgctcga cgccctcgtg gaactcggtc tcgactgggg cgccgaccgc cttgagctgg
    11521 ccaacacgca attctacggc tgggcgctgc gcaaccgcga cgcgctgctc cccggccggg
    11581 cgcaggtggc gcgggcccgc gagcgcgtcg agcggtggcg gcagcggctc gaagggcgca
    11641 tggagatcgt gtgggtggcg cccgactacg tcgacggcgt cgcgaagccc tgcatgggcg
    11701 gctggggcgc gctctcgctg accgtcgccc cggacggcag ggcgctgccc tgtccggcct
    11761 ccgccgatct cctcggcgcc gcggcgccga acgtcaggga ccgtcaactg tcctggatct
    11821 ggcgggagtc ggaggcgttc acgcgctatc gcggcgaggc gtggatgagt gacacctgcc
    11881 ggggctgcga gctgcgcgcc gtcgacttcg gcggctgccg ctgccaggcg tacgccctga
    11941 ccggcgatgc cgcccgcacg gacccggcct gtcaccgctc gcccgaccac gccatggtcc
    12001 gcgccctggt cgacggggcg gggcacgcgg ctgacgccgc cgacgcgcct cccgattacg
    12061 tctaccgcac gcacaccgcc ggaccggcac tcacgtaact ccccatgtcc gcaagggcct
    12121 tgggccctcg cacgtccccc gactgtcagg aaagtttcct gacattgccg cagagaggta
    12181 agccccacgt gagactccac gcaccccgct cccgtacccg ggtccgtccg cgcacgacga
    12241 ccgccgccct tgccgccgtc accgcgctgt ccggcgcggc ggccctgacc ctggcgggcg
    12301 agccgtccgc ccaggcgtcc cccgctcccg ccgctcgggc gtccggcacg atccacgccg
    12361 ccccctacga atacctcggc tggggaaacc cgcagaagcc gaccgacgtg atggccgcga
    12421 ccggcgtcaa gtggttcacg ctcgccttca tcctgtccga cggcggctgc gacccggcct
    12481 gggacggcag ccgtccgctg aagggcggct ccgacgaggc ggccatcaag tccatcaggg
    12541 gcgcgggcgg cgacatcgtc gtgtccgtcg gcggttggag cggggccaag ctcggcgaga
    12601 agtgtgccgg cgccgccgcg ctcgccgggg cgtaccagaa ggtcatcgac gcctacaagc
    12661 tgaaggtgtt cgacatcgac atcgaggaca ccgagttctc caacgccacc gtgcgccagc
    12721 gcgtcgtgga cgccctgaag atcgtcaagg cgaagaaccc cggcatcgtc acctacgtga
    12781 ccatgggcac cacgccgaac ggccccgacg ccaccggcaa ggacctcatc aagcgcggcg
    12841 cggcggccgg gctagccaac gacgcctggg tgatcatgcc gttcgacttc gacggccaca
    12901 gcggcaccat gggccaggcg tccgtcagcg ccatggaggg cctgaagaag gcggtcaaga
    12961 gcgcctacgg ctacagcgac gccgacgcct accggcacat cggtgtgtcc tccatgaacg
    13021 gcaagaccga cgtggcgggc gagaccgtca ccacggccga cttcaagacg atcctcgcgt
    13081 acgccaagca gcaccacatc gcgcgctact ccttctggtc cgtcaaccgc gaccgcgcgt
    13141 gcggctccgg cggtgacgcc gacgcgtgca gcggcgtcgc gcagtcgccg tacgacttca
    13201 ccaaaatcgt cgcccagtac ggaggttgag atggaactcg gcaagcagcg agccgttctg
    13261 ctggcgaccg ccgtcgtgct ggtggccggt gcggtgacca cggcgacggc gggtgcgtcc
    13321 accaccgcga cggcgggtgc ctccaccacc gccgcggccg gtgagcccgg cacgcccgtc
    13381 accctctcca ccggttggac catcccctgg gggacttcct ggctccccga cggatccggc
    13441 gccctggtca ccgagcgcga cgacttcggg gtctggcgga tatccaagga cggcaaggag
    13501 cgcaagcggg tcggcaccgt ccccgagtcg cagaccaccg gcggcgaggg cgggctgatg
    13561 ggcctcgccg tcgaccccga ctgggcgacg aaccactacg tgtacgtcat gcacacctcg
    13621 tccgagggca accgcatcgc ccgcatgacg tacgacggga cgaccgtcag cggctacaag
    13681 gtgctgctca agggcatcaa gaagaacaag taccacaacg gcggacgcct cgccttcggc
    13741 cccgacggct atctgtacgc caccacgggc gacgcccagg acaagccgct cgcccaggac
    13801 aagaactccc tcaacggcaa gatcctgcgc ctgaccacgg acgggaagcc cgcgcccggc
    13861 aaccccttcg gcaactacgc gtacagcctc ggccaccgca acccccaagg tatcgccttc
    13921 gacgcgcaag ggcgcctgtg ggaggcggag ttgggcgact ccaagaagga cgagctcaac
    13981 ctcatcaagg ccgggaagaa ctacggctgg cccacctgtg agggcacctg cgacgtcgcg
    14041 ggcatgacca accccaagcg gacctggggc gtcgcggagg cgtcgccgag cggtgtcgcg
    14101 gtcgtcgacg gggcggtcta catggcggcg ctcaagggca agcgcctgtg gcgcatcccg
    14161 accaacgccg acaacgagaa cgtcggcacc ccgaaggcgt actacatcgg cgagtacggg
    14221 cgcctgcgtt cggtcaccgc cgtgccgggc gccaaggagc tgtggctgtc caccaccaac
    14281 gccgacaaca acggcggaca gcccgaaggg tcggacacga tcttccgcgt gccgatcggc
    14341 taggcccccg ggcccgtcac ggggcggcgg ccccgaggta ggcgtcgcgc acctccgggt
    14401 ccgcgcgcac ctcggccgcc gtgccgtgcg cgaggacccg gcccaggtcg agcacgacga
    14461 cccgggcgca cagctccatc acgaaggcca cgttgtgctc gacgagcagc accgcgcagc
    14521 cctcctcgtc ggcgagatgc cgtacgacgg ccgccagttg gccccgctcg tcgcccgtca
    14581 taccggacgc gggctcgtcc aggagcagca ccctgggcgg gtccgcgacc gcgcgggcca
    14641 gctccaccat gcgggcctgc ccgaccggca gggcgcccgc gtactccccg gcgagcgcgt
    14701 cgagcccgca ctcgcgcagc accgcgtcgg cccgctcgcg ccgcgtcctc tcgtacgtac
    14761 gacgggtggg cgcggccacc aggtcggcgg cgaacccgcc acccccgccc cgccactcct
    14821 gtgccacgac gagattgtcg gcgacggtga gctgtccgaa gagctgctgc cgctggaagg
    14881 tgcggcgcat cccgtgccgg gcgcgccaca cgggggagcg gcgggtcaca tcggctccgt
    14941 cgagcaggac gctcccgtcg tccgggcggc ggatgccgga gaggacgtcg aacaaggtgg
    15001 tctttcctgc cccgttgggc ccgatgagcc cgcacacctc gccggggcgc acggcgaggt
    15061 cgacgccccg gagggcgtgg atcccgccga accggacgcc gacgcccgag gcttcgagga
    15121 cgtactgccg cttctcccgc tccctcatga ccgcgccacg cccttcgtcg tccgctgacc
    15181 ctcgcccgcc gccatgccga gatatgcctc ggtgagccgg tccgcccgca cctcggagcg
    15241 cggtccgcac caggagacgc ggccctgcgc cagataggcc acggtgtccg cgacgccgag
    15301 gatctcggcc gccttctcct ccaccaacag caacgccgtt ccctggtcgc ggagttcgac
    15361 cagcagtcgg aagacctcct cgaccacgcg tggcgcgagg ccgagcgagg gctcgtcggc
    15421 gacgaggacc gtcggcgggt gctggagcag cggcgcgagc gcgagcatct gctgctcgcc
    15481 gccggacagg gagcccgcga cgaccttgcg ccgcgcggcg agccccgcga accgctcgta
    15541 cacggcgtcg cgttcgtcct tgtccttcag gtggagggcg aggttctcct cgatggtgag
    15601 ggaggggaag atcccccggc cctcgggggc gaggaggaca ccggcccgcg accgcagcac
    15661 ggccccctcc cgggtgacat cgcgccccgc gacgtacacg tgtccctcga cgggcctgat
    15721 gagcccggcc gcgacgcgac aagtggtgga ttttcccgcc ccgttggggc cgagaagggc
    15781 gacgatctcg ccggggcgga cggtgaggtc cactccgtgg aggacggggg cgccgtcgta
    15841 cccggcgtgg attccgtgga gcgcgagggc atgattcagc ccctccggcg tttgaggagc
    15901 ggggtctggg gcggagcccc aggtgcgacg cccgcccccg ggggctctct gcacccgacg
    15961 acgatgcatc cgcaccgaga ccgccgcaca gtacccgtcc ggatcattcg ccagcgccag
    16021 ccccgcaagc ccgaagagca ccaccggcac gtgcacggac tccgtcacgt agtcggagac
    16081 caggtgcggc acgatcgcga agaccagccc cgccaccacc gcgaactgcg ccctccgcac
    16141 ccccgccgcg accgccaccg ccagccagat gagacccgtc atcgccgtga agtccgtagc
    16201 ggtgatgcgg gtgttgaagg acgcgtacat cacgcccccg aaccccgcga gccccgccga
    16261 cagcgtgaac aggagcagct tcgtccgtac gacggagacg cccgacgcca tcgccgccgc
    16321 cggcgccgac cgcaccgcca gcatggtccg ccccgacggc gagttccgca gcgcggcgag
    16381 cgcggcgacc gcgaccgtga cgaggacgac catcgccacg cccatcgcgc ggtcgtccga
    16441 gaggtcgacg ggcccgacgg cgggccgggg gatctcccag cccgtgtcgc cgttcctcaa
    16501 ccagcccagc tggaagagga cttggtcggc gaggaaggcg agcgccaggg tggcgagcgc
    16561 gagggagcgc ccgcccagcc gcagcgcggg cagtgccacg agcgcgccga gcagcgccgc
    16621 cgcgcacgtg ccgacgaggg ccgcgcccgc gaacggccac ccgtggctca tcaggagccc
    16681 ggccaccagc gccgcacccg tcacgaacgt ggcctgcgcg agcgagacca tcgcgccgag
    16741 accggtcacc acggtgaagg agacgaagac gagcgagatc gcgagcccct gcgcgaggac
    16801 gccgctccag aagggcgtcg tgaccgtgta gaaggagagc gcgagcagcg cggccgccac
    16861 cgcccacggt ccccatctgc gggtccacga gcgcccggcg agatagtcga tcggcggcgc
    16921 gtccaccgcc gccgtgcccg ccgtgcggct gcgccgcgtc atgaccagca gtccggcgaa
    16981 caggatcagg aaggggacgg ccgtacggaa cccggtgatc cgctccgcga agtcggcgta
    17041 gcccgcgacc aggttctgca gcacgccgag cccgagccca ccggcgaagg ccagcgggac
    17101 cgacaggaag cggccgagga cggcggcggt cgccgagacg aagaggaaca gcgtgaagtc
    17161 gtgcgaggag agcccgagca ggggcgtcgc gagcacgccc gcgagaccgg cgagccccga
    17221 cgacagcatc cacgccaccg aggagagccg gtccgcgctc atcccgcgca gctccaccag
    17281 ggagcggttg tcgacggcgg cccgcagtcg gaggccgagc ggggtgtgcc gcatgagcac
    17341 ccacagggcg acggcgacca gcgccgtggc cacccaggtg atcagctggt cggagtcgat
    17401 gccgacgccg tccgtcagct gccagctctt cgcggggctc gggccgacgc ccggcaggcc
    17461 gaactggttc tcggccggtt tgacgggggc acccgcgccc tccaggagct ccaccaccca
    17521 caggccgagc gcgggcagcg cgacgagcag cccgatcgtc gccacgatct gcgcggtctc
    17581 gccgacccgc gccagcttgc ggaacatcag ccggtccagg ccccagccga gcccgggggc
    17641 caccacgagg acgagcagca gcgcggtggg cacggcgggc cagccgaagc cggagcgcag
    17701 ttcgtagaag gcgagcgcgc agaggtaggc ggtggcgccg tgcgcgaagt tgaagagccc
    17761 ggacgcggag taggacagga cgagtcccgt cgcgagcagg gcgtacaggg cgccggacac
    17821 gaggccgctc aggacgaacc ccagcaggtc ggacatgggt gacgcacccc cttgtgtgca
    17881 gagccggatg tgcggtgccg gaaggggagg gtcacgtgaa ggggatgggc tcgtagcacg
    17941 tgaacggcga ggagaccgtg taggcgctgc ccttgagctg gacgagcgcg ccgcacccga
    18001 acgactcctt gtgccccttg ggcagtcggc ggtcgcccac catggtgtcg gtgtcggaga
    18061 agccgtcggc cgcccgctgg aaggactcga cgtcgaggtc cttgcccgcc ttctcggcga
    18121 tggccaggaa gaggtcggcg gacatgtagc cggtcatcat gtgcatgttg agcggcacct
    18181 tcttgcccgc ggccttcgcg atgtccttct tgaaccgccg catgtccgcg ctgtcctgct
    18241 cgaagggctg gaaggtgagg agcacgtgca ccccgtccag ggccttcttc gtcgcgctct
    18301 tggcgagcag gccggggtcg tagtcggtgg ggtcggtgag gacgcccttg aagccggtgc
    18361 gcttgacggc ggtgaacagg ccgatgttgt acggggtctg catgacggag acgaccgcgt
    18421 cgggtgcctt cccgccgttc gagcgcagga tctccttggt gtacgccgac cagtcgctgg
    18481 gcaccgacgt cgcgggcacc gtcgacttgg cgtacgtcac ctcgtacccg gcggccgcga
    18541 agctctgttg gtaggtgcgg atggcgaacg tgcccgcgtc gttgtcgttg gcgaggatcg
    18601 ccacggtctt cccctcggcg ccgcccatga ccttcttcag gccctcgggc cagctctggg
    18661 tgatcgtgcc gccgggcatc ggcaccatgc agccgccgaa tccgtacagg taactcgggc
    18721 cgcagaacgg cgggatggtg ccccagccga aggtgggcac ccgctgcttc tggaggaagt
    18781 ccgcgccgga gaaggtcacc gagctcatcg gggatatcgc gaacaccttg tcgcgctgga
    18841 cgagtttgcg ggcggcggcg aggttcttcc cgggatcctg gccgtcgtcc tccgcgccca
    18901 ggtagtcgat cttccgcccg tgcacgccgc cctccgcgtt ggcgcggtcg aagcgggcct
    18961 tcgcgccgag gtcggtgtcc ttcttgctgt agccgctggc ggtcgtcatg gagacgatgc
    19021 cgcccacctt gatggagtcg tcggtcaccc cgcgtacgga gccgccgccc ttgccgccgc
    19081 ccgcaccctc ggaaccgccg ctgttggagg cggagttgca ggcggtggcg agcagcaggg
    19141 ccgccacggt ggcggtgatg gcgctgatcg atcgcgacac ggtcgagccc cctccgtcgt
    19201 cgaagtgagg gtgattctgt gtgcgacctg atgaaccgtc aataactggc gcgtcggtaa
    19261 ttgatgaacc gtcagaaacc ggggccggtg gagcgcctag gtcttgtaca gcgcctcgac
    19321 ctcggtgagg tacgcctgct cgatcgcctt ccgcttcagc ttcagggacg gggtgagcag
    19381 cccgtgctcc tcggagaact ggtgcgccag tatccggaac gtacggatcg actcggcttg
    19441 tgagaccagg gtgttggcgg ccaccacggc ccgtcgcacc tcggtctcca gatccgggtc
    19501 gcgcaccagc tcgccggggg agagcagcgg cttgcggcgc atggtgagcc agtgctcgac
    19561 ggcctccgcg tccagcgtga cgagcgccgc gatgtagggg cggtcgttgc cgacgacgat
    19621 gcactgcgcg accagcgggt gatcgcgcac ccgctcctcc agctgggccg gtgacacgct
    19681 cttgccgcct gaggtcacca ggatctcctt cttgcgcccg gtgatcgtca gatagccgtc
    19741 ctcgtcgagg gagccgaggt caccggtggc gagccagccg tcgtgcaggc tcgccgcggt
    19801 ggccttgtga tcgcccaggt agccctggaa gacgttgccg ccgtgcagcc acacctcgcc
    19861 gtcgtcggcg atgtgcacgg tggtgccggg gatggcgagg ccgaccgtgc cgtagcgggt
    19921 gcgctcgggc gggttggcgg tcgcggcggc cgtcgactcg gtcaggccgt acccctcgta
    19981 gatcgtcacg cccgcgcccg cgaagaacag cccgagcctg cggtccatgc cggagccgcc
    20041 cgacatcgcg tgccgcaccc ggccgcccat cgcctcgcgc accttggagt agacgagctt
    20101 gtcgaagacc tggtgctgca tgcgaagcga cgccgagggt cccgagcccg tgccgaacgc
    20161 cctggcctcc atggcctcgg cgtagcgcac cgcgcactcc acggccttgt cgaacgcgcc
    20221 cgccttgccc gccgcctccg ccttgcgccg cgccgcgttg aagaccttct cgaagatgta
    20281 cggcacggcc aggatgaacg agggccggaa cgcggccaga tcgggcagca gcgccgccgc
    20341 gttcaggttc ggctggtgcc ccatcttgac ccggccgcgc accgccgcga tctgcaccat
    20401 gcgcccgaag acgtgcgcga gcggcaggaa gagcagggtc gtggcctcgt cgccgcgctt
    20461 ggagtggaag accggctccc agcgcgccac catcacatcg gcctcgaaca tgaagtttgc
    20521 gtgcgagatc agacagccct tggggcggcc cgtggtgccc gaggtgtaga tgatcgtcgc
    20581 gatcgagtcg ggcgtgaccg cgcgccggtg gcggtggacc acgtcgtcgt cgatgtcccg
    20641 gcccgcgccg ttcagttcac cgacggcgtc cgcgtccagc tgccagagcc tgcgcagctg
    20701 cggaagccgg tcgatcaccg agccgatcgt catcgcgtgg tcctcgtgct cgaccatcgc
    20761 ggcggacacc tgcgcgtcgt gcagcatcca gaagacctgc tcggccgacg acgtcggata
    20821 gatcggcacg acctgggcgc cgatggccca cagcgcgaag tcgaagagcg tccactcgta
    20881 gcgggtgcgg gacatgatgg cgacgcggtc cccgaacctg acgccctgcg cgatgagtcc
    20941 cttggccagc gcgagcacct cgtcgcggaa ttcgccggag gtgacgtcgt gccactgccc
    21001 gtccgtcttg cggccgaggg cgatgcgcag cgggtcctcg gcggcatggt cgaacacggc
    21061 gtcggcaagg ccgcccacca gcggcgccga cgccatcgga gggttcgtga actcgcgcaa
    21121 tgatgctcct tgtggcgctc cgcacagcgc cgtgacggta ccccaccccg cctgccttcg
    21181 ggagggggtc gaaacggcgt cggtacggac catcagcaca ggtcagccgg tgaaatacgg
    21241 ccacaagggt aagggtcgga cagaatgctt accctggagt aagtttcggt tccgtaatct
    21301 ccaccgaatc tgtacgcagc gtgcagacgt acgcgcccct ctcgacccga tcatcgcacc
    21361 ccgaccgtcc cgacccggtt acttgttcag gagaacccat gccagcgcac cacccgcccc
    21421 gccccgcgcg ccgagccgcc gcgacgagag gacggaggat caccggcgtg tgcgccgtgg
    21481 ccctgccgac ggcgctgctg gcgctgcaac tcgggctcgg ccccgcggcc caggcccacg
    21541 agggcgtcgg cgcggggccg cgtgcggcga gcagcgtggc ggcccccgac aaggcgacga
    21601 tctcggaagg ccaggtcgag gaggtcgcgc ccgggggcgt catcacctat ccgagcgtca
    21661 ccagttgcct cacggtgacc gtgcggctgc gggagggcgg cctcgtcggc gcgcacgcca
    21721 gcctgttcca ggtgccgggc gagctgcgct ccgatcagat cctggccgcg ctcaaggggc
    21781 gtgtcggtga ccgcgccgtg gcctcggtcg aggtcagggg agccgtcggc gcctggcatc
    21841 cgagctactt cgcgaaggcg atcgagagct acggcgaggg ggagcaggtt ccggtcccga
    21901 ccgtccccga cccggacggg atcgcccgcg cggtgtcgga ggggctcggt acggcacccg
    21961 gtctcgtctc ggtcgaggac gtgcccgacg gggaccaggt cgtcagctga cggctcagcc
    22021 cacgatgccg ctgacggcgg acagggccga gcccagcgcg gaccgtacgt tcgccgcggc
    22081 agcggtgtcg gccaggta
//
