LOCUS       NZ_CP022685            23115 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7095747
            Orig. end                         :: 7118862
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23115
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /product="furan"
                     /region_number="30"
                     /rules="AfsA"
                     /rules="(mmyO or AvrD)"
                     /tool="antismash"
     cand_cluster    1..23115
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="furan"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10957
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10957
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5957](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5957)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    248..266
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
     misc_feature    complement(276..290)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            498..788
                     /locus_tag="KY5_RS31010"
                     /old_locus_tag="KY5_6099"
     CDS             498..788
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS31010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_6099"
                     /product="hypothetical protein"
                     /protein_id="WP_098245303.1"
                     /transl_table=11
                     /translation="MRTMKRVLLAAAAASLLVASHGATAAASAPAPAPVQPAPVRSTPA
                     AGPGWHHVADFPPGEESQCHERGRWYMENGVRAYECRPAGVWELWVLTEPS"
     gene            complement(813..1871)
                     /locus_tag="KY5_RS31015"
                     /old_locus_tag="KY5_6100c"
     CDS             complement(813..1871)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS31015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_6100c"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_098245304.1"
                     /transl_table=11
                     /translation="MTIADFRTTVPSHRLRTPMAPRATPPASRVPAVLLDGPALSRTRF
                     MISPLNETLAEAARYAGSTAPHLTRHYRHRAGVRTAQADAVLQALSEALRATRWPKAGL
                     LSPARLTGITCPGLDQELGALRGRLLDADTDDEDVTVLLDALRAAYALWLADDWPGRLR
                     SLEDDLAYRAHLLIRYGAEQVIDTLHEQVSYADQLLYVTPAPAVATGTGHGTAEFPYAP
                     QRAAEGLLIVPSWTAETPALLCGGELPVLRYPARNGFDLRAESERSAPRPRAITALIGR
                     ARSHALASIGTGCSTTELADRLGVGAATASSHATALRRAGLIVTVRRGKRVEHLLTDLG
                     SRLLNAGSDAVG"
     misc_feature    complement(1947..1960)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    complement(1953..1973)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(1961..1974)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    1961..1974
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.73"
                     /tool="antismash"
     misc_feature    1969..1978
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(2016..2906)
                     /locus_tag="KY5_RS31020"
                     /old_locus_tag="KY5_6101c"
     CDS             complement(2016..2906)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="KY5_RS31020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6101c"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_159072623.1"
                     /transl_table=11
                     /translation="MVQQERARRTRERILNLTAESFAAQGFTRTNLKDVAKALGMTTGA
                     LYGHFTNKEAIADALEREAAEHWALLRGAADSPGLAPEQALDSAVFGLVRAMADPRMRA
                     VVRLAAEGPPRGTSVPNLLDAVAEFLLAQLRRAWQDDAGPARTWRPEPVTQILLGLICG
                     AVFARRGATEEESQSDWEEAARVLLGALREDGADSDRSGAVPCPPDTITYPSGAANSPS
                     DTVAYPPGAADSLSDTTTYPPGAADSLSDTMTYPPGTADSPSDTATYPPDPANTSSDTT
                     TYPPSPANAPSGTLA"
     cand_cluster    2105..23115
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="single"
                     /product="furan"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2105..23115
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[12104:13115](+)"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12105..13115
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="2"
     misc_feature    2956..2973
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.58"
                     /tool="antismash"
     misc_feature    complement(2983..2996)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.89"
                     /tool="antismash"
     misc_feature    2991..3000
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(3095..3835)
                     /locus_tag="KY5_RS31025"
                     /old_locus_tag="KY5_6102c"
     CDS             complement(3095..3835)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544620.1"
                     /locus_tag="KY5_RS31025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6102c"
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_098245306.1"
                     /transl_table=11
                     /translation="MTSTATPRAAEPRRAAFFDVDETLIATKSMFAFWDHWSARGGGGG
                     RRTGDGEGAGDGKAAGDGEGGSRGASPTGDAPVPADRAALNRAHFRRYRGARPDELSAA
                     GQEWYATYRTTPSAFVTASLSALRRHRAAGHAVVLVSGSADPMLRPLAEDLGAEAVLCT
                     ELLVGADGLLTGDVRTPMIGGAKATAVTAYLARHGLSADDSHAYGDHASDLDMLRAVGN
                     PVVVGDDPELAHWAAREGWHRLPR"
     gene            complement(3832..5052)
                     /locus_tag="KY5_RS31030"
                     /old_locus_tag="KY5_6103c"
     CDS             complement(3832..5052)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1191: acyl-CoA dehydrogenase type 2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135625.1"
                     /locus_tag="KY5_RS31030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6103c"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_234362935.1"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-07, bitscore:
                     31.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHGVGGDPSPPRRPGMLIADLTPETAGTSGVSGTSASPGDLDHAT
                     VAALADGERGAMDGRRSLSVPLADALTRAGFPRHFVPVEHGGTAGTFGALLDSVAGVGE
                     TCASTAWVAALYAAHGRLASYLPRAGRDDLWRDTPDTRIAASVIPPRGEAVPEPDGWRL
                     TGDWTLASGVDHAEWVLLASRTPGEGEAGHRVFAVPRERVSVSDTWNSVGLRGTGSNSV
                     SVTGEFVPAHRTFTLADLGQVRPGAARCHRVPYAMVASLMFAAPALGSARGALRDWRAR
                     MMTKVRADGRPALTGGAAQQLMARASAQIHSARLLLHQAAWQADHAEVTPLAVASNRRD
                     AALAVELCSGAVDSLWRAMGASGLAEGDPVQRRWHDIAAVASHAAVSFEPAAEAYTRAA
                     LEAEGLA"
     gene            complement(5001..5957)
                     /locus_tag="KY5_RS31035"
                     /old_locus_tag="KY5_6104c"
     CDS             complement(5001..5957)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041195.1"
                     /locus_tag="KY5_RS31035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6104c"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_159072624.1"
                     /sec_met_domain="AfsA (E-value: 1.6e-18, bitscore: 65.5,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKAADGEVLLQDAVRTGENRFTVAARMPRDHFLGHRGTASEGDP
                     LLLAEAVRQTVIYLSHRFYGIPEGHAFILSALDFALDEPLPPGGPDAPPLVLEAACVAA
                     PRGPRRLGATMEAEVHCEGRRIGRAGARWQAVDRRQYATLRLRGGGTTLLPEVASSELT
                     APHIPYNDAVLADVPGAEGQWQVCLDFGHPVLFDHLSDHIPGMVLLEGFRQAALLTGAG
                     SASASGSGAGSASGGIVGGPLAAAVSFHAFGELTDPPALIVRQNGEEYAGNSATESPGS
                     RATGREHHHFTAVQSGRTIASCTVSVATPLPHGGPAC"
     misc_feature    complement(6273..6287)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            6310..6975
                     /locus_tag="KY5_RS31040"
                     /old_locus_tag="KY5_6105"
     CDS             6310..6975
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011039544.1"
                     /locus_tag="KY5_RS31040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6105"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_098245309.1"
                     /transl_table=11
                     /translation="MPRPTADAAGTASVAFNARKITTARGPEPRQDRSARTKAVILDVA
                     SELFATRGFRHTSVKDIAEAVEMTKGAVYFHYPTKEALAVAVVEGHYAYWPRLLEEVQR
                     RELPPLETALAMLDGAALAFRDNVVVRGGARLQIERPHIDAELPTPYVDWTELLRSLLS
                     DAYGKGQLASDVDPGAAARSLVSAFFGVQHVSDVLHGRADITDRWAETRDLFLRALRP"
     gene            7366..8073
                     /locus_tag="KY5_RS31045"
                     /old_locus_tag="KY5_6106"
     CDS             7366..8073
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135627.1"
                     /locus_tag="KY5_RS31045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6106"
                     /product="ATP-binding protein"
                     /protein_id="WP_098245310.1"
                     /transl_table=11
                     /translation="MKIAISGTYSAGKTSTVMALAHYTGVPRTLARTIREILPETFPGK
                     ALSDVAPHEFLQLMLRRHSGRVAQEAALGEHFISDGSSLQEWLYGAGRVIHGMNPNATA
                     GNEGGKVAELSPEMRFFAKVVDQYGHALKQHVKDTYDAYVHLQHELPIAADGHRPMNEA
                     FRATIDTMLLRTLDELEIPYHVVSGSMPERLETIAGIFGLEPVMSPAEAIDLAWNDYGR
                     QDFRMETERAAAA"
     misc_feature    complement(8112..8132)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.93"
                     /tool="antismash"
     gene            8135..>8722
                     /locus_tag="KY5_RS42290"
                     /pseudo=""
     CDS             8135..>8722
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128726.1"
                     /locus_tag="KY5_RS42290"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="flavodoxin family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSTKPTVAIAYYSGYGHTDVLAQAVKDGATDAGAEVTLVRVDTIT
                     DEQWQVLDDADAIIFGSPTYMGSAAGKFHVFAESTSKRWAGAAWRDKLGAGFTNAACKA
                     GDKHSTLAYFATLGAQHQMNWVNLGLHPGWHTSTESENDLNRLGYFNGAAASTPADLPP
                     QDVSKADVATAEYLGARVAEQTAIVLAGRAAAS"
     gene            <8756..9121
                     /locus_tag="KY5_RS42705"
                     /pseudo=""
     CDS             <8756..9121
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="KY5_RS42705"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="FAAFGSGDVEGTVALFADEVDFRVSGAPNVPWTGARSAKGELAEF
                     FGTFGQVLTLPESFELTGRVTEGEHAVVTARCVFGVLATGRKFTNHYALHFTVSEGRVS
                     RYHMYEDSHAIAEAFAA"
     gene            9160..10116
                     /locus_tag="KY5_RS31055"
                     /old_locus_tag="KY5_6108"
     CDS             9160..10116
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="KY5_RS31055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6108"
                     /product="DMT family transporter"
                     /protein_id="WP_098245312.1"
                     /transl_table=11
                     /translation="MKNSALLIRTGLGPAIGGTLFFVAAHYLPPTPYWDGFFRVLPAGL
                     LLLAIRFGLPRGAWWWKSLVLGTLNMGLFTVLLLISAQRLPGGVAATLNAMSSLVAIAV
                     ASVVLKEKIRPHHYVACLVGVVGVALLVLRSSATLDAIGVLAGIGSASSMGIGTVLARK
                     WGRPEGVHSLTTAGWTLLGAAVFLLPLAFVFEGAPPSFTGKQLLGLVWAAFVVGALGFA
                     LYLSGVQRLPVSLTAPLTLMNPVTAALLGWVAVGERFTPLQLLGGVLVCAAIILVANPD
                     ILGRFFTKAEPKAEPEPKAEPAPEPVAEEQPKPVSVA"
     gene            10113..11573
                     /locus_tag="KY5_RS31060"
                     /old_locus_tag="KY5_6109"
     CDS             10113..11573
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="KY5_RS31060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6109"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_098245313.1"
                     /transl_table=11
                     /translation="MKDFDVVVVGAGPTGLVLAGLLSRAGAKVLVVERRIDRGDRPKAV
                     VLHAPTLELLDSFGLLDEVTDRSIPLERFAFHLKGTGSFTAGMTGTDTHLDGYRNMPQP
                     ILEGLLEKYALGYGARIEYGVGYLSHEAGGTGNSGDSGVLVRFEGRDDVRCSYLVGSDG
                     PRSAVRESLGVTMAGRSLSTSYLLIEGVPRELVCRDEVGVHVGANGMVTMMPIPGDQVL
                     MAGPVVNGLTLDRGASVPWRRIADAIDTLGFGSRLELAEALRTSHYSVDLRVAERWVSG
                     KVVLAGDAAHLNTPAGGQGLNLGIGDALALSWRLLAALRHDEAELLAGYEAERRPYATR
                     VGQTTFLAPLIDRMRAARDVDDPSVRAELAELALSWSQLYPDHGNPVKRHGARYELSAG
                     ARVPTWTRAADGRLTPFLAPSDRVDASTLLWFDDTEPVSVESDLPVPPVREVRRVARPA
                     ADGRVTVPDGARGLLVRPDRLVAEVIGS"
     gene            11649..12032
                     /locus_tag="KY5_RS31065"
                     /old_locus_tag="KY5_6110"
     CDS             11649..12032
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="KY5_RS31065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6110"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_159072625.1"
                     /sec_met_domain="PF07366 (E-value: 3.3e-06, bitscore: 25.8,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKAVHQFYAGSQAADADLWAGAFAENGLFHDPVGSEPIRGREAI
                     LARLRKVIPQFDPFLGITPVDAYTTGGQTAVHWRGAVVTTDGKPVNWSGISVFRLDEDG
                     LIAELWAYFHHGVFTAQLGDSEH"
     gene            12105..13115
                     /locus_tag="KY5_RS31070"
                     /old_locus_tag="KY5_6111"
     CDS             12105..13115
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) furan:
                     AvrD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017469.4"
                     /locus_tag="KY5_RS31070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6111"
                     /product="AvrD family protein"
                     /protein_id="WP_098245315.1"
                     /sec_met_domain="AvrD (E-value: 2.9e-72, bitscore: 242.7,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGTTITRERFRLGSVDDALGDRQGRFFGEGFKRVTHSLGAISIR
                     PSDASAPGGVDATAGIRIPGVWSRKGESHQRPHLSTIDAMQFAAQLTGLYVAHVHDLPP
                     SGHFVVRSLCIKAGCTPDEEFLDRFPVSALHESTRELPGTDRVSTTMECRIGSMTVRVE
                     AEHSASAAPVYTEGFYAHPEYLPGGWNDAPYGASHHGRHQYLLDVAVDADSLSADAELR
                     ITEALATPDAPATPDAPLAPTMVDLFVSALQLGQVLLYRLDGLDRATSNTLWMRGTTIT
                     PADEDPAPPVHDRRLRVALARPNELPTAQGTWRAARIQATYGGLRLACNVAHLLP"
     gene            13155..14174
                     /locus_tag="KY5_RS31075"
                     /old_locus_tag="KY5_6112"
     CDS             13155..14174
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041704.1"
                     /locus_tag="KY5_RS31075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6112"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_098245316.1"
                     /sec_met_domain="fabH (E-value: 2.4e-113, bitscore: 377.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYRPAALMGLGSYLPPWVISNEDLAAELDTTDEWITTRTGIRAR
                     HRVSPGTSTGDLAVEAGHRALKSAGLDAEPGAVDAVVLATTTPDHPCPATAPDVAARLG
                     LGPIGAYDISAVCSGFLYALATASAQITAGQAERILVIGAETYSTIINPADRTTSVIFG
                     DGAGAVVLAAAEDSGRPGVLLGVDLGSDGLHRDLISIPAGGSRQRSTPGEPDPDDRYFT
                     MQGKKVFAAAVARMAESSTSVLDSIGWTTGSVDHLVGHQANARILKALAKQLGIPEERA
                     VVHLDRVGNTSAASIPLALAHAASQGTLTPGSRVLLTAFGGGLTWGSVALTWPDVTPA"
     gene            14225..14485
                     /locus_tag="KY5_RS31080"
                     /old_locus_tag="KY5_6113"
     CDS             14225..14485
                     /NRPS_PKS="Domain: PP-binding (15-78). E-value: 1.4e-13.
                     Score: 42.9. Matches aSDomain:
                     nrpspksdomains_KY5_RS31080_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840574.1"
                     /locus_tag="KY5_RS31080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6113"
                     /product="acyl carrier protein"
                     /protein_id="WP_234362936.1"
                     /sec_met_domain="PP-binding (E-value: 1e-10, bitscore:
                     40.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMQTIAHSSTLSAELMEILTTEYEAPEGTTADTAYDMLGFDSLV
                     LVELAVALTKQFGVQVTDDELQEAGNIAGTIELLRAKGVPA"
     aSDomain        14270..14458
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS31080_PP-binding.1"
                     /evalue="1.40E-13"
                     /label="KY5_RS31080_PP-binding.1"
                     /locus_tag="KY5_RS31080"
                     /protein_end="78"
                     /protein_start="15"
                     /score="42.9"
                     /tool="antismash"
                     /translation="LMEILTTEYEAPEGTTADTAYDMLGFDSLVLVELAVALTKQFGVQ
                     VTDDELQEAGNIAGTIEL"
     gene            14578..15357
                     /locus_tag="KY5_RS31085"
                     /old_locus_tag="KY5_6114"
     CDS             14578..15357
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01490.1"
                     /locus_tag="KY5_RS31085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6114"
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_098245317.1"
                     /transl_table=11
                     /translation="MNRTRLAFFDVDGTLTTATTLFRFLRHYLAAEGHEPHEYDRRRQR
                     LKAMTEIGVPRERTNLAYFENFAGAGAARVSALARDWFAAELRQGGLFNACALDALRGH
                     RDAGDRIVLVSGSFAACLAPLAEHIGADEVWSTSPEIAHGRYTGGLNRPPMIGRAKADA
                     VRLAAAAHRAAPEDCVAYGDHASDLPMLEATGSAAVVGGDPALRALARRRCWRLLPGAP
                     APEPLPRPDAGPSPNNPECASGVSLYVSQERARTTAA"
     gene            15430..16932
                     /locus_tag="KY5_RS31090"
                     /old_locus_tag="KY5_6115"
     CDS             15430..16932
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639349.1"
                     /locus_tag="KY5_RS31090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6115"
                     /product="3' terminal RNA ribose 2'-O-methyltransferase
                     Hen1"
                     /protein_id="WP_098247576.1"
                     /transl_table=11
                     /translation="MFLTISTTGTPERPATDLGFLLHKHPEKAQAFSTSYGTAHVVYPE
                     ASDERCTAALLLEVDPVALVRRGKGKGKGRGGAPDAALAQYVNDRPYAASSLLAVALSA
                     VFSSAMRGVCAARPERAAQPLPLRIQVPALPARGGAELVRGLFEPLGWTVEATPVPLDE
                     RFPEWGESRYVRLVLDVPEGRLTLGEALRHLYVLLPVLDDAKHYWVSPDEVDKLLRAGE
                     GWLAAHPEQKVITDRYLARRWSLTREARERLELVRLAEADDTDVEEIDNAVDEETDTDE
                     QPVPLAVRRRTAILAELAASGASRVLDLGCGQGQLVQELLKDVRYTEIVGVDVSVRALT
                     VAARRLKLDRMGERRAERVTLTQGSLAYTDKRLKGYDAAVLSEVVEHLDIERLPALEYA
                     VFGSARPRTVLVTTPNVEYNVRWETLPAGHARHGDHRFEWTREEFRAWAHRVAERHGYD
                     VRFEPVGDEDPEVGPPTQLAAFTRQDKNATPGNDKKKEVRAA"
     gene            16929..19493
                     /locus_tag="KY5_RS31095"
                     /old_locus_tag="KY5_6116"
     CDS             16929..19493
                     /GO_function="GO:0004113 - 2',3'-cyclic-nucleotide
                     3'-phosphodiesterase activity [Evidence IEA]"
                     /GO_function="GO:0051731 - polynucleotide
                     5'-hydroxyl-kinase activity [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445175.1"
                     /locus_tag="KY5_RS31095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6116"
                     /product="polynucleotide kinase-phosphatase"
                     /protein_id="WP_098245318.1"
                     /transl_table=11
                     /translation="MTNDISTGTEAARAARVLPVTDLSLVVLIGATGSGKSTFARRHFA
                     PTEVLSSDFCRGLVADDENDQGASRDAFDVLHYIAGKRLAAGRRTVVDATSVQSDSRKQ
                     LIELARAHDVLPIAIVLDVPEEVCAERNAARADRAGIPRRVIQRHQRELRRSLRNLERE
                     GFRKVHVLRGVAEVEAAEIVTEKRYNDLTHLVGPFDIIGDIHGCASELDTLLGKLGYVE
                     GAHPEGRTAVFVGDLVDRGPDTPGVLRRVMSMVADGTALCVPGNHENKLGRYLKGRGVQ
                     HTHGLAETAAQLAEESDEFRAQVREFVDGLVSHYVLDGGRLVVCHAGLPEKYHGRTSGR
                     VRSHALYGDTTGETDEFGLPVRYPWAEEYRGKAAVVYGHTPVPTATWLNNTICLDTGAV
                     FGGRLTALRWPERELVDVPAEQVWYEPSRPLGTEAPGGHEGRPLDLNDVRGRRVVESRH
                     AGRVAVREENAAAALEVMSRFAVDPRLLPYLPPTMAPTATSQCEGYLEHPAEAFASYAA
                     DGVARVVCEEKHMGSRAVALVCRDADAARERFGTDGPTGSLYTRTGRPFFSDGSVTEEI
                     LDRLRAAVTEAGLWEELATDWLLLDAELMPWSLKASGLLRTQYAAVGAASGAVFPDALA
                     ALEAAKARGVDTGALLAGQRERAADAAAFTDAYRRYCWPTDGLEGVRLAPFQLLAVQGR
                     SLAGLPHDEQLALIDRMVEHDGTGLLRTTRRLYVDTGDEESVRAGVDWWLEMTSRGGEG
                     MVVKPVGALVRDGKGRLVQPGIKCRGREYLRIIYGPEYTRPENLAKLRGRFLGHKRSLA
                     IREYALGLEALDRLAEGEPLWRVHESVFAVLALESEPVDPRL"
     gene            19556..20788
                     /locus_tag="KY5_RS31100"
                     /old_locus_tag="KY5_6117"
     CDS             19556..20788
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983758.1"
                     /locus_tag="KY5_RS31100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6117"
                     /product="arginine deiminase"
                     /protein_id="WP_098247577.1"
                     /transl_table=11
                     /translation="MGFHVDSEAGRLRRVILHRPDLELKRLTPSNKDALLFDDVLWVRR
                     ARQEHDGFADVLRDRGVEVHLFGDLLTETLDVPEARLLVLDRVFDEKEYGPLATDHLRM
                     AFETLPSAQLAEALIGGMTKREFLAGNAEPTSVRFHCMDLDDFLLGPLPNHLFTRDTSA
                     WIYDGVSINAMRWPARQRETVHFEAIYQHHPLFRGAGFNIWSQGQADYPSTIEGGDVLV
                     IGKGAVLIGMSERTTPQAVEMLAHKLFAAGSAKTIVALDMPKRRAFMHLDTVMTMVDGD
                     TFTQYAGLGMLRSYTIEPGVGERELKVTDHPPEHMHRAIAAALGLSEVRVLTATQDVHA
                     AEREQWDDGCNVLAVEPGVVVAYERNSTTNTHLRKQGIEVIEIRGSELGRGRGGPRCMS
                     CPVERDAVPGA"
     misc_feature    complement(20841..20857)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.97"
                     /tool="antismash"
     gene            20889..21887
                     /gene="argF"
                     /locus_tag="KY5_RS31105"
                     /old_locus_tag="KY5_6118"
     CDS             20889..21887
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639346.1"
                     /locus_tag="KY5_RS31105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_6118"
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_098245319.1"
                     /transl_table=11
                     /translation="MATDLTGRHFLKELDFTADEFRGLLDLAAELKAAKKAGTETQLLR
                     GRNVALIFEKSSTRTRCAFEVAAADQGASTTYIDPAGSHIGTKESAKDTARVLGRMFDA
                     IQFRGDAQETVETLAAHAGVPVYNGLTDEWHPTQMLADVLTMTEHSAKPLAEIAFAYLG
                     DARFNTGSSYLITGALLGMDVRLVAPRAYWPADEIVAKARELAEDSGARITLTEDVPEG
                     VRGADFVVTDVWVSIGEPKQVWAERIAALAPYAVTMDVLRATGNADVKFLHCLPAFHDL
                     GTTVAREIHETYGLESLEVTDEVFESAHSVVFDEAENRLHTIKAILVATLA"
     misc_feature    22162..22176
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(22718..22733)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.64"
                     /tool="antismash"
     misc_feature    23007..23022
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.79"
                     /tool="antismash"
     misc_feature    complement(23077..23097)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
ORIGIN
        1 cgcctccctg gaggacagtg agcggcagtt cggccgggtc cgcgcggccg ccgagcaggc
       61 cgggcgcaag ggggacgacc tggtgtactc cagcgcgctg gtggcctgcg tcggcaagga
      121 cgacgcggag gtcgcccggc gcgcggccgt catcggacgc gaggtggacg agctcaaggc
      181 caacggcctc gcgggctccc cggccgaggt cgtggacaag atcggcaagt acgcggagat
      241 cggtgcgagc cgtatctacc tccagtgcct ggacctggcc gacctggacc acctggagct
      301 gatctcctcc caggtccagt cgcagctgtc gtaggcgggc gacgccggcc ccgggccttc
      361 gtcggcccgg gccaaggacg tgaccgccgg gctcacccct ccggtgcccg gtggtcactt
      421 caccctttgg gccaatcggg ggaaggcgga gcggtctccg tccatgtggg cccgccagct
      481 gcggaaggat gccttccatg cgaaccatga aacgcgtact cctcgcggct gcggccgcgt
      541 cgttgctggt ggcgagccac ggcgcgactg ccgcggcctc ggcgcccgcc cccgcgcccg
      601 tacagcccgc gcctgtacgg tccacgccgg cggccgggcc gggctggcac cacgtggcgg
      661 actttcctcc gggcgaggag agccaatgtc acgagcgcgg ccgctggtac atggagaacg
      721 gcgtccgcgc ctacgagtgc cggcccgccg gggtctggga gttgtgggtt ctcaccgagc
      781 cctcctgacc agggcctgcg gccacccggt gctcagccga ccgcgtcgct gcccgcgttc
      841 aggaggcggg agcccaagtc ggtgagcagg tgctccacgc gcttgccgcg ccggaccgtg
      901 acgatcagcc ccgcgcggcg cagcgccgtg gcgtggctgg aggcggtcgc ggctcccacg
      961 ccgagccggt cggcgagttc cgtggtgctg catccggtgc cgatggaggc cagcgcgtgg
     1021 gagcgggccc ggccgatcag cgcggtgatc gcccgtggcc gtggggcgga gcgctcgctc
     1081 tcggcgcgca ggtcgaagcc gttgcgggcg gggtagcgca gtacgggcag ttcgccgccg
     1141 cagagcaggg ccggggtctc ggccgtccag ctgggcacga tgagcagccc ctcggccgcg
     1201 cgctgcgggg cgtacgggaa ctcggccgtg ccgtgtcccg tgccggtcgc gacggccggg
     1261 gccggggtga cgtacagcaa ctggtcggcg tagctgacct gttcgtggag ggtgtcgatg
     1321 acctgctcgg cgccgtaccg gatcaacagg tgggcgcggt aggcgagatc gtcctccagc
     1381 gatctgagtc tgccgggcca gtcgtcggcg agccacaacg cgtaggccgc gcgcagggcg
     1441 tcgagcagga cggtgacgtc ctcgtcgtcg gtgtccgcgt cgagcagcct gccgcgcagg
     1501 gcgccgagct cctgatccag gccggggcag gtgatgccgg tgagtctggc gggggagagg
     1561 agtccggcct tcggccaccg ggtcgcgcgc agcgcttccg acagggcctg gaggacggcg
     1621 tcggcctggg cggtgcgcac gcccgcgcgg tgccggtagt ggcgggtgag gtgcggggcg
     1681 gtggaccccg cgtaacgggc cgcctcggca agggtttcgt tgagcggcga gatcatgaac
     1741 cgggtgcggg acagggcggg gccgtccagg aggacggcgg ggacgcggga ggcgggcggg
     1801 gtggctcggg gggccatcgg ggtgcggagg cggtggctgg ggacggtggt gcggaagtcg
     1861 gcgatggtca tgacgggcct ttcaggcgtg gtgagtcggg gtggtggagc ggtgtgttgg
     1921 ggcgtggtga ggtgtcgtga ggtgcagaaa aaaacctttg caaaggtatg ttttttggtc
     1981 ggatgggcgc ggtcgacgat gaccgtgccc gagggtcagg cgagcgttcc cgagggggcg
     2041 ttggccgggc tcggcgggta ggtggtcgtg tccgaggagg tgttggccgg gtctggcggg
     2101 taggtcgccg tgtccgaggg tgagtcggct gttcccggcg ggtaggtcat cgtgtccgag
     2161 agggagtcgg ctgctcccgg cgggtaggtg gtcgtgtccg agagggagtc ggccgctccc
     2221 ggcgggtagg ccaccgtgtc cgagggggag ttggctgctc ccgagggata ggtgatcgtg
     2281 tccggggggc aggggaccgc gcccgagcgg tcgctgtcgg cgccgtcttc ccgcagcgcg
     2341 ccgagcagga cgcgcgccgc ctcctcccag tccgactgcg actcctcctc cgtggcgccg
     2401 cgccgggcga agaccgcgcc gcagatgagg ccgagcagga tctgggtgac gggctcgggg
     2461 cgccacgtgc gggcggggcc cgcgtcgtcc tgccaggcgc ggcgcaactg ggcgagcagg
     2521 aactcggcca cggcgtccag caggttcggc acggaggtcc cgcgcggcgg gccctcggcg
     2581 gccagtctga cgaccgcgcg catgcgcggg tcggccatgg ccctgacgag gccgaagacc
     2641 gcgctgtcca gggcctgttc gggggccagg ccgggagagt cggcggcgcc gcgcagcagg
     2701 gcccagtgtt cggcggcctc gcgctccagc gcgtcggcga tcgcttcctt gttggtgaag
     2761 tggccgtaga gcgcgccggt ggtcatgccc agcgccttgg ccacgtcctt gaggttggtg
     2821 cgggtgaatc cctgggccgc gaagctctcg gccgtgaggt tcaggatgcg ttctctggtg
     2881 cgccgggccc tctcctgctg gaccatgtgt gactccttcc gccggtgcga cgccgtcgtc
     2941 gtgtctccgg ccgccttgtc atcctcacgt aaaattcctt cctgaaggta tgttttttgg
     3001 atactcgtca attcccttct ctccctgggg cttctttctc gggtctcttc ccgtagctcg
     3061 cccgcgccgt cggcgcgggc gagcggggga gtggtcatcg cggcagccgg tgccagccct
     3121 cgcgggccgc ccagtgggcc agttccgggt cgtcgccgac cacgacgggg ttgccgacgg
     3181 cgcgcagcat gtccaggtcg ctcgcgtggt cgccgtacgc gtggctgtcg tcggcggaca
     3241 gtccgtgccg ggccaggtag gcggtgaccg cggtggcctt ggcgccgccg atcatcgggg
     3301 tcctgacgtc gccggtgagc aacccgtcgg cgccgacgag cagttcggtg cagagcaccg
     3361 cttcggcgcc taggtcttcg gcgagcgggc ggagcatcgg gtccgccgaa ccggagacca
     3421 ggaccacggc gtgccccgcg gcccggtgtc gtcgcagggc cgagagcgac gcggtgacga
     3481 aggccgaagg ggtggtgcgg tacgtggcgt accactcctg tcccgccgcg ctcagttcgt
     3541 cggggcgcgc gccccggtag cgccggaagt gggcccggtt gagggcggcg cggtcggcag
     3601 ggaccggggc gtcgccggtc ggcgacgccc cgcggctgcc gccctcgccg tctccggcgg
     3661 ccttgccgtc cccggcacct tcgccatccc ccgtacgcct cccgcccccg ccgccccgcg
     3721 ccgaccagtg gtcccagaag gcgaacatgc tcttggtcgc gatcagcgtc tcgtccacgt
     3781 cgaagaacgc cgcccggcgc ggctccgccg ccctcggcgt cgctgtcgac gtcatgccag
     3841 gccctccgcc tctagcgcgg cccgcgtgta cgcctcggcg gccggttcga agctgaccgc
     3901 cgcgtgcgag gccaccgccg cgatgtcgtg ccaacgccgc tgcaccgggt ctccttcggc
     3961 gaggccgctc gcgcccatgg cccgccacag gctgtccacc gcgcccgagc acagctcgac
     4021 ggcgagcgcc gcgtccctgc ggttcgaggc gacggcgaga ggcgtcacct cggcgtggtc
     4081 cgcctgccag gcggcctggt gaagcagcag ccgggcggag tggatctggg ccgaggcgcg
     4141 cgccatcaac tgctgtgccg cgccaccggt gagggcagga cgtccgtcgg cccgcacctt
     4201 cgtcatcatc cgggcccgcc agtcgcgcag cgcgccccgc gcggagccca gggcaggggc
     4261 cgcgaacatc agagaggcca ccatcgcgta cggaacccgg tggcagcgcg ccgcgcccgg
     4321 gcgtacctgg cccaggtcgg cgagcgtgaa cgtgcggtgc gcgggcacga actcgcccgt
     4381 cacggagacc gagttgctgc cggtgccgcg caggccgacg gagttccagg tgtcgctgac
     4441 cgagacccgc tcgcggggta cggcgaagac gcggtgtccc gcttcgccct cgccgggcgt
     4501 gcggctggcg agcagcaccc actccgcgtg gtccacgccg ctggccagcg tccagtcgcc
     4561 cgtcaggcgc cagccgtccg gctcggggac ggcctcgccg cgcggcggga tgacggacgc
     4621 ggcgatgcgc gtgtccggcg tatcgcgcca caggtcgtcg cggcccgcgc gcgggaggta
     4681 ggaggcgagg cggccgtgcg ccgcgtagag ggcggcgacc caggcggtcg aggcgcaggt
     4741 ctcgccgacg cccgccaccg agtcgagcag ggcgccgaag gtacctgcgg tgccgccgtg
     4801 ttccacgggg acgaagtggc gcgggaaccc ggcccgggtg agcgcgtcgg cgagcggcac
     4861 ggagagcgag cgccgtccgt ccatcgcgcc gcgctcgccg tccgcgaggg cggcgacggt
     4921 ggcgtggtcg aggtcacccg gggacgcgga ggtcccggag accccggagg tcccggcggt
     4981 ttcgggagtg aggtcggcga tcagcatgcc gggccgccgt gggggagagg ggtcgccacc
     5041 gacaccgtgc aagaagcgat ggtgcggccg gactggaccg cggtgaagtg gtggtgctcc
     5101 cgccccgtgg cccgtgaacc ggggctctcc gtggcggagt tgcccgcgta ctcctcgccg
     5161 ttctgccgga cgatcagcgc gggcgggtcc gtgagttcgc cgaaggcgtg gaaggagacc
     5221 gccgccgcga gcggcccgcc gacgatgcca cccgaagccg aacccgcacc cgaacccgaa
     5281 gccgacgccg aacccgcccc cgtcagcaga gccgcctgcc ggaagccctc cagaaggacc
     5341 atccccggta tgtggtcgct gaggtggtcg aagagcacgg ggtggccgaa gtcgaggcac
     5401 acctgccact ggccttccgc gcccggcacg tccgccaaca ccgcgtcgtt gtaggggatg
     5461 tgaggagccg tcaactcact gctcgccacc tccgggagga gcgtcgtgcc cccgccccgc
     5521 agccgcagcg tcgcgtactg ccgacggtcc accgcctgcc accgcgctcc ggcgcgcccg
     5581 atgcggcggc cttcgcagtg gacctccgcc tccatggtcg cgccgaggcg gcgcggaccg
     5641 cgcggggccg cgacgcaggc ggcctccagg accagcggcg gcgcgtcggg gccgccgggc
     5701 ggcagcggct cgtccagcgc gaagtccagc gccgacagga tgaaggcgtg gccctcggga
     5761 atgccgtaga agcggtgcga gaggtagatc accgtctggc ggaccgcctc ggcgagcagc
     5821 aggggatcac cctcggacgc cgtgccgcgg tggccgagga agtggtccct cggcatccgg
     5881 gccgccacgg tgaaccggtt ctcgccggtg cgcaccgcgt cctggagcag gacctcgccg
     5941 tccgcggcct tgtgcaccca cttcctcggt acgtgggtgc tcccgcgcgg cacgtgcgcg
     6001 ccctgtcgtt caccccctga cgccgggcgt cttccgtccg gcgcttcctc atgcgtatgc
     6061 gtccgctccc cagcggaaaa ggcatgcaca gtcatctcga atccctcccc gtcggcgccc
     6121 ggaggttcag accccccctc cggacaccga tcaagcaacc ccgtgagacg gctgcaggaa
     6181 tgctctgaac agcgcgtctc ttgatccgtt gatcagcggg gtcgaaaata tacctacagg
     6241 aaggtatctt tcaagcctca gagtcgaccc catggccgat acggaccgca cccggagaac
     6301 tgacgcctca tgccacgacc caccgccgac gccgccggga ccgcctcggt ggccttcaac
     6361 gccaggaaaa tcaccaccgc gcgcggcccc gagccacggc aggaccggtc ggcgcgcacc
     6421 aaggccgtca tcctcgacgt ggcgtcggag ctgttcgcca cgcggggctt ccggcacacg
     6481 tccgtcaagg acatcgccga ggcggtcgag atgaccaagg gggcggtgta cttccactac
     6541 ccgacgaagg aggcgctcgc cgtcgccgtc gtcgagggcc actacgcgta ctggccccgg
     6601 ctgctcgaag aggtgcagcg gcgggagctg ccgccgctgg agacggccct cgccatgctc
     6661 gacggcgcgg ccctcgcctt ccgggacaac gtggtggtgc gcggcggcgc ccggctgcag
     6721 atcgagcgcc cgcacatcga cgccgaactc cccacgccgt acgtggactg gacggagctg
     6781 ctgcgctccc tgctgtccga cgcgtacggc aaggggcagc tcgcgtcgga cgtcgatccg
     6841 ggggccgcgg cccggtccct ggtgtccgcg ttcttcggcg tgcagcacgt ctccgacgtc
     6901 ctgcacggcc gcgccgacat caccgaccgc tgggcggaga cgcgcgatct cttcctccgg
     6961 gcgctgcggc cctgaggcgg cggagcaggc ggatcgccga cagatcgagg acacccgctc
     7021 ggtgagcggg gtgcggggag gaccgtgaga cacggtcctc ccttcggcgt tttcggggcg
     7081 ccgagccacg ggcgggcccg cgccgtcacc gatgcttttc ggccgccctc gaaatgatgc
     7141 gctgtcatgc cccatggttt cgggggcctg tcgaatcgtt cgcgccagcg ggcgcacttt
     7201 cctaagttcc tgtctgcgcc accgaggccg tcgccgaaac gcccggccga cggacgacag
     7261 aagaccgtgt gcgcgcagta cgccgcagcg caccgcatct cggcccgtgc cgcgccgggt
     7321 gcgcgtcgag cgggccgaat tctccgagcc gaaaggcccc tacgcatgaa gatcgctatt
     7381 tccggcacct actccgcggg caagacatcg acggtgatgg cgctggccca ctacaccggc
     7441 gtaccgcgca ctctggcacg caccattcgg gagatcctgc cggagacctt tcccggcaag
     7501 gcgctctcgg acgtggcgcc gcacgagttc ctgcagctga tgctgcgcag gcactcgggc
     7561 cgcgtcgccc aggaggccgc gctcggcgag cacttcatct ccgacggctc ctcgttgcag
     7621 gagtggctgt acggcgcggg ccgcgtcatc cacgggatga accccaacgc caccgcgggc
     7681 aacgagggcg gcaaggtggc cgaactctcc ccggagatgc ggttcttcgc caaggtcgtc
     7741 gaccagtacg gtcacgcgct gaagcagcac gtcaaggaca cctacgacgc gtacgtgcac
     7801 ctccagcacg agctgcccat cgccgccgac gggcaccgcc cgatgaacga ggcgttccgc
     7861 gcgaccatcg acacgatgct gctccggacg ctcgacgagc tggagattcc gtaccacgtc
     7921 gtcagcggct cgatgcccga gcgcctggag accatcgcgg ggatcttcgg tctcgaaccc
     7981 gtcatgagcc ccgcggaagc gatcgacctg gcgtggaacg actacggccg ccaggacttc
     8041 cgcatggaga ccgagcgcgc cgccgcggcc tgagccgacc gcacgaaccc cacgagcctc
     8101 agcaacccaa gaacctcacc ggaggaatgt ctacatgtcc acaaagccca ccgtcgcgat
     8161 cgcctactac tcgggttacg gccacaccga cgtgctggcg caggccgtca aggacggtgc
     8221 gaccgacgcc ggggcggagg tcaccctggt ccgcgtcgac acgatcaccg acgagcagtg
     8281 gcaggtgctc gacgacgcgg acgcgatcat cttcggctcg ccgacgtaca tgggctcggc
     8341 cgccgggaag ttccacgtgt tcgcggagtc cacgagcaag cggtgggcgg gcgcggcctg
     8401 gcgcgacaag ctgggcgcgg gcttcaccaa cgcggcgtgc aaggccggtg acaagcactc
     8461 cacgctcgcc tacttcgcga cgctgggcgc ccagcaccag atgaactggg tgaacctggg
     8521 cctgcacccg ggctggcaca cgagcaccga gtcggagaac gacctcaacc ggctcgggta
     8581 cttcaacggc gccgcggcca gcacccccgc cgacctgccg ccccaggacg tctccaaggc
     8641 ggacgtcgcc accgccgagt acctcggcgc ccgggtcgcc gagcagaccg cgatcgtcct
     8701 cgccgggcgc gcggccgcct cgaccgccgc caccgacacc gtcgtcgacg cgttcttcgc
     8761 cgccttcggc tccggagacg tcgaagggac cgtcgcgctc ttcgccgacg aggtggactt
     8821 ccgcgtcagc ggcgcgccga acgtcccgtg gaccggcgcg cgctccgcca agggtgaact
     8881 cgccgagttc ttcggcacgt tcggacaggt cctcaccctg ccggagtcgt tcgagctcac
     8941 cgggcgggtg accgagggcg agcacgccgt cgtgacggcc aggtgcgtct tcggggtgct
     9001 ggccacggga cgcaagttca ccaaccacta cgcgctgcac ttcacggtct ccgaaggccg
     9061 cgtgagccgc taccacatgt acgaggacag ccacgccatc gccgaggcct tcgccgcctg
     9121 acccgcgccc ctggccgtac cttccacgga gctcaccaga tgaaaaactc agccctcctc
     9181 atccgcaccg gactcggtcc ggccatcggc ggcaccctct tcttcgtcgc cgcccactac
     9241 ctgccgccga cgccctactg ggacggcttc ttccgggtgc tgcccgccgg gctgctgctc
     9301 ctcgcgatcc gcttcggcct gccgcgcggc gcgtggtggt ggaagtcgct cgtgctcggc
     9361 acgctcaaca tgggcctgtt caccgtcctg ttgctgatct cggcacagcg gctgcccggc
     9421 ggtgtggcgg ccaccctgaa cgccatgtcg agcctggtgg ccatcgcggt cgcctcggtg
     9481 gtcctcaagg agaagatcag gccgcaccac tacgtcgcct gcctcgtcgg cgtcgtcggt
     9541 gtcgcgctgc tcgtgctgcg cagttcggcc acgctcgacg cgatcggcgt cctcgccggc
     9601 atcggctccg cgtccagcat gggcatcggc acggtactcg cccgcaagtg gggccgtccc
     9661 gagggcgtgc acagcctcac cacggcgggc tggaccctgc tcggcgcggc cgtcttcctg
     9721 ctgccgctcg cgttcgtctt cgagggcgcg ccgccgagct tcaccggcaa gcagctcctg
     9781 ggcctcgtct gggccgcgtt cgtggtcggc gcgctcggct tcgccctcta cctctccggc
     9841 gtccagcgcc tcccggtgtc cctgaccgcg ccgctcaccc tgatgaaccc ggtcaccgcg
     9901 gccctgctcg gctgggtggc ggtcggcgaa cggttcaccc cgctgcaact cctcggcggc
     9961 gttctcgtct gcgccgcgat catcctggtc gcgaacccgg acatcctggg ccggttcttc
    10021 accaaggccg aacccaaggc cgaacccgag cccaaggccg agcccgcgcc ggagccggtg
    10081 gccgaggagc agccgaagcc ggtgtcggtg gcatgaagga cttcgatgtc gtcgtggtcg
    10141 gcgccgggcc caccggcctc gtcctcgcgg gactgctctc acgggccgga gcgaaggtcc
    10201 tggtcgtgga gcgcaggatc gacaggggcg accgccccaa ggccgtcgtg ctgcacgcgc
    10261 caacgctcga actcctcgac tccttcggcc tgttggacga ggtgaccgac cgcagcatcc
    10321 cgctcgaacg gttcgccttc cacctcaagg gcaccgggtc cttcaccgcc gggatgacgg
    10381 ggacggacac ccatctggac ggctaccgca acatgccgca gccgatcctg gaggggctcc
    10441 tcgagaagta cgcgctcgga tacggcgcac ggatcgagta cggcgtcggc tacctgtccc
    10501 acgaggcggg cggcacgggg aactcgggcg actcgggcgt cctggtccgc ttcgagggcc
    10561 gcgacgacgt ccgctgctcc tacctggtcg gcagcgacgg gccgcgcagc gccgtgcgcg
    10621 agtccctggg cgtcacgatg gcggggcgca gcctctccac gagctacctg ctgatcgaag
    10681 gggtcccccg ggaactggtc tgccgcgacg aggtcggcgt gcacgtcggg gcgaacggca
    10741 tggtcacgat gatgccgatc cccggtgacc aggtcctcat ggcgggcccc gtggtcaacg
    10801 gactcaccct ggaccggggt gcgtcggtgc cgtggcgccg gatcgcggac gcgatcgaca
    10861 cgctgggctt cggcagccgt ctggagctgg cagaggccct gcgcacgagc cactactccg
    10921 tggacctgag ggtcgccgaa cggtgggtga gcggcaaggt cgtcctggcc ggggacgccg
    10981 cacacctgaa cacccctgcc ggggggcagg ggttgaacct cggcatcggc gacgccctcg
    11041 ccctgtcctg gaggctgctc gcggcgctgc ggcacgacga agcggaactg ctcgcggggt
    11101 acgaggcgga acggcggccc tatgcgacgc gggtcggaca gaccacgttc ctcgccccgc
    11161 tcatcgaccg gatgcgggcc gcgcgggacg tcgacgaccc gtccgtacga gcggagttgg
    11221 ccgagctcgc gctgagctgg agccagctct acccggacca cgggaacccc gtgaagcggc
    11281 acggcgcacg ctacgagctg agcgccgggg cgcgcgtgcc cacctggacc agggccgccg
    11341 acggccggct tacgccgttc ctcgcaccga gcgaccgcgt cgacgcttcc acgctgctgt
    11401 ggttcgacga cacggagccc gtgtcggtgg agagcgatct gccggttccc ccggtacggg
    11461 aggtgcgccg ggtcgcccgg cccgccgccg acggccgcgt caccgtgccg gacggcgcga
    11521 ggggactcct cgtacggccg gaccggttgg tcgccgaggt catcggttcc tgaacgactc
    11581 cttcctttac ccaccgccta tccatgaatt cacctgagaa agagagaaat acgatgacgt
    11641 ttcccgctat gcccaaggca gttcaccagt tctacgccgg ttcgcaggcc gccgacgccg
    11701 acctctgggc cggagccttc gccgagaacg gccttttcca cgacccggtc ggcagcgagc
    11761 cgatccgtgg ccgtgaggcg atcctcgccc ggctgcgcaa ggtgatcccc cagttcgacc
    11821 cgttcctcgg catcacgccc gtcgacgcct acaccacggg cggccagacc gccgtgcact
    11881 ggcgcggtgc cgtcgtcacc accgacggca agccggtcaa ctggtcgggc atctcggtct
    11941 tccgcctcga cgaggacggt ctgatcgccg agctctgggc ctacttccac cacggcgtct
    12001 tcaccgcgca gctcggcgac agcgagcact gacgcacgca cgtccctccc cgcccgcgcg
    12061 ggcggggagg gcccgaatca gggcaacaca aagggggacc aaccatgcag ggcaccacca
    12121 tcacccggga gagattccgt ctcggctccg tcgacgacgc cctgggcgac cgacaaggac
    12181 gcttcttcgg cgagggcttc aagcgcgtca cgcacagcct gggcgccatc tccatccgcc
    12241 cctccgacgc ctcggcgccg ggcggcgtcg acgccacggc ggggatccgc atccccggcg
    12301 tctggtcccg caagggcgag tcgcaccagc gcccgcacct gtcgaccatc gacgccatgc
    12361 agttcgcggc ccagctcacc ggcctgtacg tggcccacgt ccacgatctg cccccgtcgg
    12421 gccacttcgt cgtacggtcg ctgtgcatca aggcgggctg cacgcccgac gaggagttcc
    12481 tcgaccggtt cccggtctcc gcgctgcacg agtcgacccg cgaactgccg ggcacggacc
    12541 gcgtgtcgac cacgatggag tgccgcatcg gctcgatgac cgtccgggtc gaggccgagc
    12601 actccgcgtc cgccgcgccc gtctacaccg agggcttcta cgcccacccc gagtacctgc
    12661 cgggcgggtg gaacgacgcg ccgtacgggg cgtcccacca cggacgccac cagtacctcc
    12721 tcgacgtggc ggtcgacgcc gactccctgt cggccgacgc cgaactgcgg atcaccgagg
    12781 cgctcgccac ccccgacgcg cccgccaccc ccgacgcgcc gctcgcgccg acgatggtcg
    12841 acctcttcgt gtcggccctg caactgggtc aggtcctgct ctaccggctc gacggactcg
    12901 accgcgccac gtccaacacc ctctggatgc gcggcaccac catcaccccg gccgacgagg
    12961 accccgcgcc gcccgtgcac gaccggcgcc tgcgcgtggc cctggcccgc ccgaacgaac
    13021 tgcccaccgc ccagggcacc tggcgcgccg cgcggatcca ggcgacgtac ggcggtctgc
    13081 ggctcgcctg caacgtcgcc cacctcctgc cctgaccgac caccgcactc cgcaaccgga
    13141 aaggaaggcc acgcatggcg taccgacctg ccgcgctcat gggactcggc agctacctcc
    13201 cgccctgggt gatcagcaac gaggacctcg cggccgaact cgacaccacc gatgagtgga
    13261 tcaccacgcg gaccggcatc cgcgcccgcc accgggtctc gcccggcacc tcgacggggg
    13321 acctcgccgt cgaggcgggg caccgggcgc tgaagtcggc gggactcgac gcggaaccgg
    13381 gcgccgtgga cgccgtcgtc ctcgccacca ccacgccgga ccacccctgc ccggccaccg
    13441 cgcccgacgt cgccgcccgc ctggggctcg gtcccatcgg ggcgtacgac atctcggccg
    13501 tgtgctccgg attcctctac gccctggcca ccgcctccgc gcagatcacc gccggacagg
    13561 ccgagcgcat cctggtgatc ggggccgaga cgtactcgac catcatcaat cccgccgacc
    13621 ggaccacctc ggtgatcttc ggcgacgggg cgggcgccgt cgtcctcgcc gcggccgagg
    13681 actccggtcg gcccggcgtc ctgctcggcg tcgacctggg ctccgacggc ctgcaccgcg
    13741 acctcatcag cattccggcc ggtggctccc ggcagcgctc caccccgggt gaacccgacc
    13801 ccgacgaccg gtacttcacg atgcagggca agaaggtgtt cgccgcggcg gtcgccagga
    13861 tggcggagtc gtccacctcg gtgctcgaca gcatcggctg gaccaccgga tcggtcgacc
    13921 acctggtggg ccaccaggcc aacgcgcgca tcctcaaggc gctcgccaag cagctcggca
    13981 tccccgagga gcgggccgtc gtccatctcg accgggtcgg caacacctcg gccgcctcga
    14041 tcccgctggc gctggcgcac gcggcgtcgc agggcacgct cacgccgggc tcacgcgtcc
    14101 tgctcaccgc gttcggcggc gggctcacct gggggtcggt cgccctgacc tggcccgacg
    14161 tgacgcccgc ctgaccctca cgcaccacga ctcctctcta ctccagaaca gcgagttatc
    14221 tgtcatgacc atgcaaacca ttgcccactc ctccaccctc tccgccgagt tgatggagat
    14281 cctcaccacc gagtacgagg cgccggaggg caccaccgcc gacaccgcgt acgacatgct
    14341 cggcttcgac tccctcgtgc tcgtcgagct ggccgtcgcg ctgaccaagc agttcggcgt
    14401 gcaggtcacc gacgacgagc tccaggaggc cgggaacatc gcggggacca tcgagctcct
    14461 gcgcgccaag ggcgtgcccg cctagtccgg cgccgcacgg accgagcggg gcggcggccg
    14521 gtccccaccg ggccgccgcc cgcccgcact tcgccccgac caccccgagg agcaccgatg
    14581 aaccgcacca ggctggcgtt cttcgacgtc gacggcaccc tgaccacggc gaccaccctc
    14641 ttccgtttcc tgcgccacta cctggccgcc gaggggcacg agccgcacga gtacgaccgg
    14701 cggcgccagc ggctcaaggc catgacggag atcggcgtac cgagggagcg cacgaacctc
    14761 gcgtacttcg agaacttcgc gggggccggc gccgcgcgcg tgtcggcgct ggcgcgcgac
    14821 tggttcgccg ccgagctccg gcagggcggc ctcttcaacg cctgcgcgct cgacgccctg
    14881 cgcgggcacc gggacgcggg ggaccggatc gtgctcgtct ccggttcgtt cgccgcctgc
    14941 ctcgcgccgc tcgccgagca catcggcgcc gacgaggtct ggtcgacctc gccggagatc
    15001 gcgcacggcc gctacaccgg agggctcaac cgcccgccca tgatcggccg cgcgaaggcc
    15061 gacgccgtgc gtctcgccgc cgccgcgcac cgggccgcgc ccgaggactg cgtcgcctac
    15121 ggcgaccacg cctcggacct gcccatgctg gaggccaccg gatccgccgc ggtcgtcggc
    15181 ggcgatcccg cgctgcgcgc gctcgcccgg cgccgctgct ggcggctcct gcccggcgcc
    15241 ccggccccgg agccgctgcc gcgccccgac gcgggcccga gcccgaataa tcccgagtgt
    15301 gcctccggtg tttcgctgta cgtttcacag gaacgcgcgc ggaccaccgc ggcgtgacac
    15361 cggcgcgtgc gccacaccgg cgggaccggt gcgtacgcac agctcagact ccctttcgag
    15421 gcccaccccg tgttcctgac gatcagcaca accggcaccc ccgaacgccc ggcgaccgac
    15481 ctcgggttcc tgctccacaa gcaccccgag aaggcgcagg cgttctccac gtcgtacggc
    15541 accgcgcacg tcgtctaccc cgaggcgagc gacgagcgct gcacggccgc gctgctcctg
    15601 gaggtcgatc ccgtcgcgct cgtgcggcgc ggcaaaggca agggcaaggg ccggggcggt
    15661 gcgcccgacg cggcgctcgc gcagtacgtg aacgaccggc cctacgccgc gtcctcgctg
    15721 ctcgcggtgg cgctgagcgc ggtgttctcc agcgcgatgc gcggcgtgtg cgccgcgcgt
    15781 cccgagcggg ccgcgcagcc gctgccgctg cggatccagg tgcccgcgct gcccgcgcgc
    15841 ggcggcgccg agctggtgcg ggggctcttc gagccgctgg gctggacggt ggaggcgacg
    15901 cccgtgccgc tggacgagcg gttccccgag tggggcgaat cgcggtacgt gcggctcgtg
    15961 ctcgacgtgc ccgagggcag gctgaccctg ggcgaggcgc tgcggcacct ctacgtgctg
    16021 ctcccggtgc tcgacgacgc caagcactac tgggtctcgc ccgacgaggt cgacaagctg
    16081 cttcgcgcgg gtgagggctg gctcgcggcc cacccggagc agaaggtcat caccgaccgc
    16141 tatctggcgc gccgttggtc cctgacccgc gaggcgaggg agcggctcga actggtgcgg
    16201 ctcgccgagg ccgacgacac ggacgtcgag gagatcgaca acgcggtcga cgaggagacc
    16261 gacaccgacg aacagccggt gccgctcgcc gtgcgccgcc gcacggcgat cctcgccgag
    16321 ctggccgctt cgggcgcctc gcgcgtgctc gacctgggct gcgggcaggg ccagttggtg
    16381 caggaactgc tcaaggacgt ccgctacacc gagatcgtcg gcgtggacgt gtccgtgcgc
    16441 gcgctgaccg tcgccgcgcg gcggctgaag ctggaccgca tgggcgagcg cagggccgag
    16501 cgcgtcacgc tgacgcaggg ctcgctcgcg tacaccgaca agcggctcaa ggggtacgac
    16561 gccgccgtgc tcagcgaggt cgtcgagcac ctcgacatcg agcggctgcc cgccctggag
    16621 tacgcggtgt tcggctccgc gcggccccgc accgtcctcg tgaccacgcc gaacgtcgag
    16681 tacaacgtgc gctgggagac cctgcccgcc ggacacgcgc ggcacggcga ccaccgcttc
    16741 gagtggaccc gcgaggagtt ccgcgcctgg gcccaccggg tcgccgaacg gcacgggtac
    16801 gacgtgcggt tcgagcccgt cggggacgag gaccccgagg tgggaccgcc gacccagctg
    16861 gcggccttca cgcggcagga caagaacgcg acacccggca acgacaagaa gaaggaggtg
    16921 cgggccgcat gacgaacgac atcagtaccg gcaccgaagc agcccgcgcg gcccgcgtgc
    16981 tgcccgtcac cgacctctcc ctcgtggtcc tgatcggcgc cacgggatcg ggcaagtcca
    17041 ccttcgcgcg caggcacttc gcgcccaccg aggtcctctc cagcgacttc tgccgggggc
    17101 tcgtcgccga cgacgagaac gaccagggcg cgagccgtga cgccttcgac gtgctgcact
    17161 acatcgcggg caagcgcctg gccgcgggac gccgcaccgt cgtcgacgcg accagcgtgc
    17221 agagcgacag ccgcaagcag ctgatcgagc tggccagggc gcacgacgtg ctgcccatcg
    17281 ccatcgtgct cgacgtgccc gaggaggtct gcgccgagcg caacgccgcg cgcgcggacc
    17341 gggcgggcat cccgcgccgc gtcatccagc gccaccagcg cgaactgcgc cgctccctgc
    17401 ggaacctgga gcgcgagggc ttcaggaagg tgcacgtcct gcggggcgtg gcggaggtcg
    17461 aggccgccga gatcgtcacc gagaagcggt acaacgacct cacccacctc gtcgggccct
    17521 tcgacatcat cggcgacatc cacggctgcg cctccgaact ggacaccctg ctcggcaagc
    17581 tcggctacgt ggagggggcg caccccgagg gccgtaccgc cgtgttcgtc ggcgacctcg
    17641 tcgaccgggg cccggacacc cccggcgtgc tgcgccgcgt gatgtcgatg gtcgcggacg
    17701 gcaccgcgct ctgcgtgccg ggcaaccacg agaacaagct cggccggtac ctcaagggcc
    17761 ggggcgtcca gcacacccac ggactcgccg agaccgccgc gcagttggcg gaggagagcg
    17821 acgaattccg ggcccaggtg cgggagttcg tggacgggct cgtctcgcac tacgtcctgg
    17881 acggcggaag gctggtcgtc tgccacgccg ggctgcccga gaagtaccac ggccgtacgt
    17941 cgggccgggt gcgctcgcac gcgctgtacg gcgacacgac cggcgagacc gacgagttcg
    18001 gcctgccggt gcgctacccg tgggcggagg agtaccgggg caaggccgcg gtcgtctacg
    18061 gccacacccc cgtgcccacc gcgacctggc tgaacaacac catctgcctg gacaccggcg
    18121 cggtgttcgg cgggcggctc accgcgttgc gctggccgga gcgcgagctc gtcgacgtac
    18181 cggccgaaca ggtctggtac gagccgtcga ggccgctggg caccgaggcg ccgggcgggc
    18241 acgagggacg cccgctcgac ctgaacgacg tgcggggccg ccgggtggtg gagagccggc
    18301 acgcgggccg cgtcgccgtg cgcgaggaga acgcggccgc ggctctggag gtcatgagcc
    18361 gcttcgccgt cgatccgcgg ctgcttccgt acctgccgcc gacgatggcg ccgacggcca
    18421 cgtcgcagtg cgaaggctac ttggagcacc cggccgaggc gttcgcctcg tatgccgctg
    18481 acggcgtcgc ccgcgtcgtg tgcgaggaga agcacatggg ctcgcgcgcg gtggccctgg
    18541 tctgccgtga cgcggacgcg gcccgcgagc ggttcggtac ggacggcccc accggctcgc
    18601 tctacacccg cacgggacgg cccttcttct ccgacgggtc cgtcaccgag gagatactcg
    18661 accgcctgcg cgccgccgtc accgaggcgg gcctgtggga ggagctggcc accgactggc
    18721 tgctgctcga cgccgagttg atgccctggt cgctcaaggc gtccgggctg ctccgcacgc
    18781 agtacgcggc ggtgggcgcc gcgtccggag ccgtcttccc cgatgcgctc gccgccctgg
    18841 aagcggcgaa ggcgcgcggt gtggacaccg gcgcgctgct cgccgggcag cgcgaacggg
    18901 ctgccgacgc ggccgcgttc accgacgcct accggcgcta ctgctggccg acggacggcc
    18961 tcgaaggggt gcggctcgcg ccgttccagc tcctcgccgt ccagggcagg agcctcgccg
    19021 gtctcccgca cgacgagcag ctcgcgctga tcgaccgcat ggtggagcac gacggcacgg
    19081 gcctgttgcg gaccacgcgc aggctgtacg tcgacacggg cgacgaggag tccgtccgcg
    19141 cgggcgtcga ctggtggctg gagatgacca gcaggggcgg cgagggcatg gtcgtcaagc
    19201 cggtcggggc cctggtccgc gacggcaagg gccgcctcgt ccagcccggc atcaagtgcc
    19261 ggggccgcga gtacctgcgg atcatctacg gtcccgagta cacgcgcccg gagaacctgg
    19321 cgaagctgcg cggccgtttc ctcggccaca agcgctcgct cgccattcgg gagtacgccc
    19381 tcggcctgga ggccctggac cggctcgcgg agggtgagcc gctgtggcgg gtgcacgagt
    19441 cggtgttcgc ggtcctcgcc ctggagtcgg agccggtgga cccgaggctc tgagcacgcc
    19501 tttgggtgtg tcattgcccg cgcgtaggcc gtccggccgg ggaaagatgg actccatggg
    19561 attccatgtc gactccgagg ccgggcggct gcgccgcgtc atcctgcacc gccccgatct
    19621 ggagctcaag cgtctgactc cgagcaacaa ggacgccctg ctcttcgacg acgtcctgtg
    19681 ggtgcgcagg gcccgccagg agcacgacgg gttcgcggac gtgctgcgcg accggggcgt
    19741 cgaggtccac ctcttcggcg atctgctgac cgagaccctg gacgtgccgg aggcccggct
    19801 cctcgtcctc gaccgggtct tcgacgagaa ggagtacggg ccgctggcca ccgaccacct
    19861 gcggatggcc ttcgagacgc tgccgtccgc ccaactggcc gaggcgctga tcggcgggat
    19921 gaccaagcgg gagttcctcg cgggcaacgc cgagccgacg tccgtgcgct tccactgcat
    19981 ggacctggac gacttcctgc tcggtccgct gcccaaccac ctcttcacgc gcgacacctc
    20041 ggcctggata tacgacggcg tctcgatcaa cgcgatgcgc tggcccgcgc ggcagcgcga
    20101 gaccgtgcac ttcgaggcga tctaccagca ccacccgctg ttccgggggg ccggcttcaa
    20161 catctggtcg caggggcagg cggactaccc ctccaccatc gagggcggcg acgtcctggt
    20221 gatcggcaag ggcgcggtcc tcatcggcat gagcgagcgc accacgccgc aggccgtcga
    20281 gatgctcgcg cacaagctgt tcgcggcggg ctcggcgaag acgatcgtgg cgctcgacat
    20341 gccgaagcgg cgcgcgttca tgcacctgga caccgtcatg acgatggtcg acggcgacac
    20401 cttcacgcag tacgcggggc tcggcatgct ccgctcgtac accatcgaac cgggcgtcgg
    20461 cgagcgggag ttgaaggtga ccgaccatcc gcccgagcac atgcaccggg cgatcgccgc
    20521 agcgctcggc ctgagcgagg tccgggtcct gaccgccacc caggacgtgc acgcggccga
    20581 gcgcgagcag tgggacgacg ggtgcaacgt cctcgcggtg gagccgggcg tcgtcgtcgc
    20641 ctacgagcgg aactcgacga cgaacacgca tctgcgcaag cagggcatcg aggtgatcga
    20701 gatcaggggg agcgagctgg ggcgcggcag gggcggtccc cgctgcatga gctgtccggt
    20761 ggagcgggac gcggtgccgg gggcgtagcc agtaccctcg ccggtccgcg cccgttcccg
    20821 cgtgtataga aatgtggagc atcgtatata gtttcaatgt ccccgtatcc gcatcccagg
    20881 agcgccccat ggccacagac ctcaccggcc gccacttcct caaggagctg gacttcaccg
    20941 ccgacgagtt ccgcggcctg ctcgacctgg ccgccgagct gaaggcggcg aagaaggccg
    21001 ggaccgagac gcagctcctg cgcggcagga acgtcgccct gatcttcgag aagagctcca
    21061 cgaggacgcg ctgcgccttc gaggtggccg ccgccgacca gggcgcgtcg acgacgtaca
    21121 tcgacccggc gggctcgcac atcggcacca aggagtccgc caaggacacc gcccgggtgc
    21181 tcggccggat gttcgacgcg atccagttcc gcggggacgc gcaggagacc gtcgagacgc
    21241 tcgccgccca cgcgggcgtg ccggtctaca acggcctgac ggacgagtgg caccccaccc
    21301 agatgctcgc cgacgtcctc acgatgaccg agcacagcgc caagcccctc gccgagatcg
    21361 ccttcgccta cctcggcgac gcccgcttca acacgggcag ctcgtacctg atcaccggcg
    21421 ccctgctcgg catggacgtc cgcctggtcg cgccccgggc ctactggccc gccgacgaga
    21481 tcgtcgcgaa ggcccgcgag ctggccgagg acagcggtgc ccgcatcacg ctcaccgagg
    21541 acgtccccga gggcgtgcgc ggcgccgact tcgtcgtcac cgacgtctgg gtgtccatcg
    21601 gcgagcccaa gcaggtgtgg gccgagcgca tagccgccct cgcgccgtac gcggtgacga
    21661 tggacgtcct gcgcgccacg gggaacgcgg acgtgaagtt cctgcactgc ctgcccgcct
    21721 tccacgacct cggcaccacg gtcgcgcgcg agatccacga gacctacggc ctggagtccc
    21781 ttgaggtcac cgacgaggtc ttcgagtcgg cgcactccgt cgtcttcgac gaggccgaga
    21841 accggctgca caccatcaag gcgatcctcg tcgcgaccct ggcctgaccg ttcccaccgc
    21901 accaccccag caccaccaga aacgagaacc accccatgag ccccacgagt cccaccgggc
    21961 ttcgcatcaa gtctcccgag cagctcgtcg ccgagtcggg cgccgacctc gaaggccacg
    22021 gcctcaagcg caccatgggg ctcttccagc tcgtgtgttt cggcgtcggc gccatcgtcg
    22081 gcaccgggat cttcgtgggg ctttccgact cggtcgccga ggcgggtccc gccgtcgcgg
    22141 tctcctatgt gctcgcggcc gtgacctgca tcttcaccgc gttctcgttc gccgagctgg
    22201 gcggtgccat cccggtctcc ggcagctcgt actccttcgc gtacgcctcc ctcggtgagc
    22261 gcaccgcgtt cctggtgggc tggtgcctgc tcctggagta cggcgtctcg gtctccgccg
    22321 tcgcggtggg ctggagccag tacctcaacg aactcctcaa cagcctcacc ggctgggagc
    22381 tgcccaccgc cctgtccgcc ggacccggcg agggcggcgt cgtgaacctg cccgccgtgg
    22441 tcgtcatcct gctcgccgcc accctcctgg tgcgcggcat cagggagagc gcgggggcga
    22501 cggccgccat ggccgtactg aagatcggca tcctgctgct cttcctcgcg atcgccttct
    22561 cggcgttcga ggacggcaac ctggcgccct tcatgggcgc gggggtctcc ggcgtcaccg
    22621 cgggcgcctc gctcgcgttc ttctccttca tcggcttcga cgcggtcacc acggcgggcg
    22681 aggaggtcag gaacccgcgg cgcaacatcc cgctcgcgat catgatctgc atcggggtcg
    22741 tgaccctgct ctacgtcgcg gtggcgctcg ccgccatcgg cgcgatcggc tctgacgcgg
    22801 tcgccgacaa gcccgccgcg ctctccctga tcgtcaacca ggtcaccgag tcgacggtcg
    22861 gcggcggcgt catcgccttc ggcgcggtcg tcgccatcgc ctcggtcgtg ctcgccgtga
    22921 tgtacggcca gacccgcatc ctgatgtcga tgtcccgcga cggcctgatg ccgcgcgtct
    22981 tcgaacgcgt ctcgccgagg acgtccacgc cggtggccaa cacctggatc gtcgcggccg
    23041 tcgtcgccgt gcccgccgcc ttctcctcgc tcgacgtggt cgtcaacctg accaccatcg
    23101 gcacgctcgc gatca
//
