LOCUS       NZ_CP022685            21089 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6206314
            Orig. end                         :: 6227403
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="28"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21089
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11089](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11089
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(22..1053)
                     /locus_tag="KY5_RS27275"
                     /old_locus_tag="KY5_5371c"
     CDS             complement(22..1053)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="KY5_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5371c"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_098244705.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRGLPVGGREGMPRMTTGIPEQQAKPHPEDP
                     GKPGPLTVADVSEQAEPTAEEGLRKLSGRGGGRRAGNMSEHEHSRHDPQDRSGARAMFI
                     ELRALKDGSREYAELRNQLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRF
                     DPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTATAELSQLHGRSP
                     TVHELAEKLAISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEY
                     RESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLL
                     VEE"
     gene            complement(1050..1463)
                     /locus_tag="KY5_RS27280"
                     /old_locus_tag="KY5_5372c"
     CDS             complement(1050..1463)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="KY5_RS27280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5372c"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_030780840.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGQVDSTVAEDNTVSISLYKKRGAGPGPA"
     misc_feature    1619..1632
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            complement(1723..1983)
                     /locus_tag="KY5_RS27285"
                     /old_locus_tag="KY5_5373c"
     CDS             complement(1723..1983)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="KY5_RS27285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5373c"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_055551725.1"
                     /transl_table=11
                     /translation="MNECSHVTALPHPEPEPLSETCLECLAVGSHPVQLRLCLLCGHVG
                     CCDSSPFQHATAHFKDTGHPVMRTFEPGESWRWCFVDGSIV"
     gene            2030..3628
                     /locus_tag="KY5_RS27290"
                     /old_locus_tag="KY5_5374"
     CDS             2030..3628
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639610.1"
                     /locus_tag="KY5_RS27290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5374"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_098244706.1"
                     /transl_table=11
                     /translation="MDVLPLVALIAASAVVAGAARRTPVPAPLLLVGVGLIAAYVPGVP
                     GYHLDPHVVLPLILPPLLHTAALESSYLDLRANLRPVALLSVGYVLFATLAVGWLAYLL
                     IPDLPLTAALVLGAVIAPPDAVAATAIARRVGLPSRITTILQGESLVNDATAITAYKVA
                     LAAAVGEGASWAGGIQEFLVAAVGGVGVGLLLMVPIHWLRTHLKEAMLQNTLSLLIPFV
                     AYAAAEQVGASGVLAVVVVALYLGHRSWQVDFETRLQEAAVWRVVAFILESAVFALIGL
                     QLPVVLKGLGEYSVGQAVWYAVGVFVFVVLVRFVWSYPATYLPRWLSTRIKEREDDMDW
                     RRPLIVSWAGMRGVVSLAIAFSIPLVMDDGEPFPARNLVLFLTFTTVIGTLVVQGLSLP
                     WLIRVLKLPGRDAQAQTLAEAQAQNAASQAAEARVEELMRDRRNCLPPPLQDRLRTVLE
                     RRRNSVWERLGQPNPVTGESADDTYRRLAREAIAAEREVFVRMRDERRIDDEMMRTLLR
                     KLDLEEAAAYREVED"
     gene            complement(3607..4566)
                     /locus_tag="KY5_RS27295"
                     /old_locus_tag="KY5_5375c"
     CDS             complement(3607..4566)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105586.1"
                     /locus_tag="KY5_RS27295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5375c"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_098244707.1"
                     /sec_met_domain="PALP (E-value: 3.7e-16, bitscore: 58.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPTPPVTPAPAALRPRLPSPLQDVDDDRFTRHGVRLRLKRDDLI
                     HPDLPGNKFRKLVLNLAAATDAGHDTLLTFGGAYSNHLRATAAAGRLLGLATIGVVRGD
                     ELAERPLNPSLTRCVSDGMRLRFVDRSTYRRKHEPGTLAGLLSAAGARDAYVIPEGGSN
                     SLAVRGCTALGEELRESTDVAAVACGTGGTLAGLAAGLGPDRRALGIPVLKGGFLGPEI
                     RALQRGTFGAPTANWHLDDRFHCGGYARTTPELRAFAEDFEDRHGDELGLSVERLYVAK
                     LLYALTALSEEGAFRPGTRLTAVITGAREDTSQSSTSR"
     gene            complement(4630..5220)
                     /locus_tag="KY5_RS27300"
                     /old_locus_tag="KY5_5376c"
     CDS             complement(4630..5220)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009306036.1"
                     /locus_tag="KY5_RS27300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5376c"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_098244708.1"
                     /transl_table=11
                     /translation="MAPPMSAGRFLDILRDEGVTVVEVGDWEHHNRNHKGPWGPVHGVV
                     IHHTVTSGSQRTVEICRDGYASLPGPLCHGVITKDGHVHLVGYGRANHAGLGDDDVLRA
                     VIAEKRLPPDNEANTDGNRYFYGFECENLGDGEDPWPDEQLEAIEKVSAAICRHHGWTE
                     RSVIGHLEWQPGKVDPRGFTMDWMRDRIEERLK"
     gene            complement(5360..5596)
                     /locus_tag="KY5_RS27305"
                     /old_locus_tag="KY5_5377c"
     CDS             complement(5360..5596)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985347.1"
                     /locus_tag="KY5_RS27305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5377c"
                     /product="hypothetical protein"
                     /protein_id="WP_098244709.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQSALAQGKQKVDEVQEKRAGDALLKKLGAAYYA
                     ERRGTGSPQATQQALQALESHVAANGDGFLHGT"
     gene            complement(5699..8302)
                     /locus_tag="KY5_RS27310"
                     /old_locus_tag="KY5_5378c"
     CDS             complement(5699..8302)
                     /NRPS_PKS="Domain: LPG_synthase_C (523-832). E-value:
                     2.7e-98. Score: 320.6. Matches aSDomain:
                     nrpspksdomains_KY5_RS27310_LPG_synthase_C.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LPG_synthase_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF021445.4"
                     /locus_tag="KY5_RS27310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5378c"
                     /product="DUF2156 domain-containing protein"
                     /protein_id="WP_159072603.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 3.7e-96,
                     bitscore: 320.6, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSEASAAAAEDPAPSAPLAPPGERGPVRWLRAVGRAFEPARRA
                     PVTVFVVVALWAVGAFTGSLGGGPPEALLNDVGVGVPALAGGRWWTPLTSLLWCSGIGN
                     YVGSTLLLLLLGSAAEQRMGSARTGVVLFIGQVLGSLLGTGVVELGSLAGEDWLDGLAR
                     DLTATPGIAACAVGAFLSFRLSALWRRRLQLTLIVFPLMLALYVGHLQNVLVLFGTVVG
                     LGLGALAHRETHRLRMPHASHSEGRVLVALVVAASAIGPLVATLYKDSLGPFNVLDLYV
                     SGGPSAQEIADACVSAGTECARVRAEDHFYGSPAMLMGIAIPLLLLVLAEGLRRGLRLS
                     WRITVAAQLLWLGLMAYLLSDIASHADRYVLEGSEQADQKAAMIQAVVEQMLLPLLVLV
                     LLLLARRLFDQLLAKATVTWLLGTVGGALLLACLAYVGIGYAVRDQFTPEATFAKLVSG
                     LPTQFFPPSYEPFFFQGQAPVPVGGTALALYEYCGMLFWVVTLIALFVAFRRPLTHADD
                     EAATRARALLAAHGGATLSYLTTWPGNHYWFAADGRAAVAYRVHSTVALTTGDPFGAAS
                     ARADAIDGFAEYCDERGWTPCFYSVTAETKARTDALGWSAVQVAEDTVVPLAELAFTGK
                     KWQDVRTALNKAKKDGITAEWHSFPDAPIALTDQIRSISEEWVADKGLPEMGFTLGGLD
                     ELDDPHVRCLLAVDEDRTVHGITSWMPVYGDVGALGDGAEPRPVGWTLDFMRRRSDGFR
                     GSMEFLIASAALGFKEEGAEFLSLSGAPLARSDTGEPPAALQRLLDHAGRVLEPVYGFR
                     SLLNFKAKFQPRYHPMYMCYPDPAALPNITRAIGKAYLPHMKPSQGVRLMRKLTA"
     aSDomain        complement(5807..6733)
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS27310_LPG_synthase_C.1"
                     /evalue="2.70E-98"
                     /label="KY5_RS27310_LPG_synthase_C.1"
                     /locus_tag="KY5_RS27310"
                     /protein_end="832"
                     /protein_start="523"
                     /score="320.6"
                     /tool="antismash"
                     /translation="RALLAAHGGATLSYLTTWPGNHYWFAADGRAAVAYRVHSTVALTT
                     GDPFGAASARADAIDGFAEYCDERGWTPCFYSVTAETKARTDALGWSAVQVAEDTVVPL
                     AELAFTGKKWQDVRTALNKAKKDGITAEWHSFPDAPIALTDQIRSISEEWVADKGLPEM
                     GFTLGGLDELDDPHVRCLLAVDEDRTVHGITSWMPVYGDVGALGDGAEPRPVGWTLDFM
                     RRRSDGFRGSMEFLIASAALGFKEEGAEFLSLSGAPLARSDTGEPPAALQRLLDHAGRV
                     LEPVYGFRSLLNFKAKFQPRYHPMYMCY"
     gene            8486..9892
                     /locus_tag="KY5_RS27315"
                     /old_locus_tag="KY5_5379"
     CDS             8486..9892
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="KY5_RS27315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5379"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_098244711.1"
                     /transl_table=11
                     /translation="MSVGEEIRAESEQPQQSLGTSAARNLATTTKSAPQMQEISSRWLL
                     RMLPWVQVQGGTYRVNRRLSYSVGDGRVTFVKTGDQVQVIPAELGELPVLRDFEDQDVL
                     GELAQRCRQREFAAGEVLASFGSAADEVFLLAHGRVEQIGTGPYGDDTVLGTLADGAYF
                     GEQALVDAESIWEYTTRAVTACTVLTLPRQDLEQVAERSESLRAHLQQLRTVPAQRTNA
                     FGEAAIDLSAGHVGEAVLPGTFVDYESSPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     HQLRLTVEALKERQEHELINNREFGLLNNCEYDQRLQPHDGVPSPDDLDELLSRRRGSK
                     LFLAHPRAIAAFGRELNKRGLVPETIDVGGTRIPTWRGVPIYPCNKIPVTEARTTSIIC
                     MRTGEDEQGVVGLHQTGIPDEIEPSLSVRFMGISEQAIISYLVSTYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            10001..11089
                     /locus_tag="KY5_RS27320"
                     /old_locus_tag="KY5_5380"
     CDS             10001..11089
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674923.1"
                     /locus_tag="KY5_RS27320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5380"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_199843264.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.9e-53, bitscore:
                     178.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTAGSGFRTGSEAEAGAGREAGEILAAARLCVDPELRRAVDS
                     LPGSMRRVALYHFGWEHADGTAAAGHAGKAIRPALVLAAVRALGGEPAMAVRAAAAVEL
                     IHNFTLLHDDVMGRDPTRRHRPAAWTVFGDADAILAGDALQALAQRLLAEDPHPGASVA
                     AARLAACVVELCAGQHADWALERRGPDEVTLDECLAMAEARTGALLGCACALGAVYAGA
                     GCEEVEALDGFGREAGLAFQLIDDVIGIWGDPGRAGKPAGADLAARRKSLPVVAALGSG
                     TVAAGELAELYGTGAAGSGSGEGELARVAVAVERAGGRDWAQVHAADRMSRAVGQLARA
                     VPDPEAAGGLLALAEFVTRRTY"
     gene            11397..12011
                     /locus_tag="KY5_RS27325"
                     /old_locus_tag="KY5_5381"
     CDS             11397..12011
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491246.1"
                     /locus_tag="KY5_RS27325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5381"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_098244713.1"
                     /transl_table=11
                     /translation="MGVAIRRAGVADRADIVRLLDEAFLRDPVSSWVFPGEEHRRRMHG
                     GLMAAFFDLALAEGYVDVTEDGDAAALWWSVPGGVAEGEEDGPALLREAVDAENERVEL
                     IGRLTDAIHPTDRAHEYLHMIAVRPERQGEGLGTELVNAVLERCDRDGLHAYLEASNAR
                     SRDLYARLGFVFMGTALDLPDGPRMWPMWREPRGVVGGVSG"
     gene            12059..12412
                     /locus_tag="KY5_RS42670"
     CDS             12059..12412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953993.1"
                     /locus_tag="KY5_RS42670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_234362879.1"
                     /transl_table=11
                     /translation="MGSDGGGAGPGVQGEPVCARCGQIVGTAIRRRKVLGVFVPVWGPG
                     PCRNPECAAYVVDEESGEAAVRRRGHGHSHSRVRSRGRRDAEGPGVSGGVGSSGGEDAP
                     DVGSADAGAAGGR"
     gene            12599..13546
                     /locus_tag="KY5_RS27335"
                     /old_locus_tag="KY5_5382"
     CDS             12599..13546
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764718.1"
                     /locus_tag="KY5_RS27335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5382"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_234362880.1"
                     /transl_table=11
                     /translation="MLAFLVELAVYAALRDRLPGRMASHFGPDGAADGYVGRGAFLAVG
                     GGLFVGLGAVGAFVALKSGYRAYRRGVVGLLAGCWATAAFLGWPMTASLVANRDLADGA
                     SARFPLWQLAVTVGVAAVAAGIGALLGLALARRTALPDVHGGGAVRDTDAARLGLGDAE
                     QAGWVRRTGSPWLFGLGVATAGAGVGLAWVQREWVAPLSLVAAGLLVAAFARPCVAVDR
                     RGLTVSPSVVPWPRVRLPLDRMERADSEYVNAVGDYGGWGYRVWPGRSGIILRSGEALV
                     VRRTSGRVFAVTVEDSATAAALLNTLVERRTAER"
     gene            13551..13910
                     /locus_tag="KY5_RS27340"
                     /old_locus_tag="KY5_5383"
     CDS             13551..13910
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458277.1"
                     /locus_tag="KY5_RS27340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5383"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_098244715.1"
                     /transl_table=11
                     /translation="MLFRIDTTSAVPLGDQIAACARRAVVDGSVGPGERLPAARMLAGS
                     LGVNVHTVLRGYQRLRDEGLIELRRGRGAIVADSAAARARAQLVERVREFVSDALDLGL
                     SDDEVLSMVGAALKA"
     misc_feature    complement(13554..13567)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            14108..14950
                     /locus_tag="KY5_RS27345"
                     /old_locus_tag="KY5_5384"
     CDS             14108..14950
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS27345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_5384"
                     /product="hypothetical protein"
                     /protein_id="WP_098244716.1"
                     /transl_table=11
                     /translation="MRTSADVPELPLDAYELSDRDNRRMGQAKSRLVQRCMRSYGFADF
                     PLNPRPEPFPKMGSAFTSTVVSISPYGTLDLGHARRWGYGFDPDATFTPKAEGPEGRAV
                     TQREYEVLNDFGEAGRTAAVVNGRKVPNGGCTGESSRRLLGDETKRSRLWAYVDERAEE
                     IDKVVAKDPRVRRIFGEWSRCVQDKGYKAYESPRDAFRDKAWRDGAPDGNTARSQRELG
                     TAVADVECNRKLNVAGVWWVVSDEEQRADIRRHAARYEAVRADQERLRGTLREVLGEK"
     gene            complement(14965..15477)
                     /locus_tag="KY5_RS27350"
                     /old_locus_tag="KY5_5385c"
     CDS             complement(14965..15477)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010275084.1"
                     /locus_tag="KY5_RS27350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5385c"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_098244717.1"
                     /transl_table=11
                     /translation="MHFNHYGGEAALLAADLVNSLAPAPPLAPLLAARGVTDHALTTAQ
                     EADLRDWAVRLAECFGPQDLPRRCARVNALLAHASSSPRISLHDGHPHFHYSAPAADPA
                     AHVRALTAAGLAYVVCFAEAHRLGRCARTPCGTAFVDTSRNGRRAYCSVRCANNDAVAR
                     HRERRRH"
     gene            16056..16859
                     /locus_tag="KY5_RS27355"
                     /old_locus_tag="KY5_5386"
     CDS             16056..16859
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="KY5_RS27355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5386"
                     /product="EamA family transporter"
                     /protein_id="WP_234362881.1"
                     /transl_table=11
                     /translation="MFVQIVSLQCGSALAKGTYGQVGPTALAGMRLGFAALVLWTVVRP
                     RLSRLSAAQWRAAAGLGVVFAGMNSAYFQAIRHLPLGVAATLELLGPLALALALSRRAA
                     HLLSGLLALAGVLLLAVPGGALPGVGVMAGAVAALCRAGYVVLNQRVGRLFSGWDGLTV
                     ALGIGACLLVPVAGAVDGRSVVEHPALLGTGFLVALLSSLIPYCLDMLALRRIGARAFG
                     VLLALGPAVGTGVGYAALGERLGLREYAAVALVVAAAAWSVRTAE"
     gene            complement(16926..17756)
                     /locus_tag="KY5_RS27360"
                     /old_locus_tag="KY5_5387c"
     CDS             complement(16926..17756)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381901.1"
                     /locus_tag="KY5_RS27360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5387c"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_234362882.1"
                     /transl_table=11
                     /translation="MNRHDRDTHDRDTNDRHIPFARLHNVRDLGGLRTADGGLVRSGLL
                     YRADSLGKLRADDGADEAERADWARFCALGPRAVVDLRYDWEIAAKGRVPELPGLAYHQ
                     LSIEHRPYDQAALGPDVEPGPYLAERYVEVAHDGVKEIRAVLDVIAASAAAKEPLVFHC
                     ASGKDRTGLIAALVLALVGVPEDAIVEDFALTGLASDRLLADWRTTHPEATGIWPGYGK
                     APSEVMTLFLAALTERYGSVRGYADELLGTDEEFAAALRRALVEVAVEAEAERG"
     gene            17815..18477
                     /locus_tag="KY5_RS27365"
                     /old_locus_tag="KY5_5388"
     CDS             17815..18477
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138325.1"
                     /locus_tag="KY5_RS27365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5388"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_098244719.1"
                     /sec_met_domain="HAD_2 (E-value: 1.6e-07, bitscore: 30.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISGRAFDAVLSDLDGVIRFYDMAELEQSERAAGLAVGSTAEIA
                     FAPETDLPLMRGEITKDQWTEAIAHGLADRVPHERGRELATTLAEAKFRADEVVVGMLR
                     QARAAGLPVLLVTNATPWLADDLALLGLTGPTGLVDDVISSADLGIVKPDRRIYEVAAE
                     RAGVAPARCLFVDDRQENVDAAAALGMTGLLYRDHADLRAVLEPALRTGARARARGD"
     gene            complement(18474..19415)
                     /locus_tag="KY5_RS27370"
                     /old_locus_tag="KY5_5389c"
     CDS             complement(18474..19415)
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430693.1"
                     /locus_tag="KY5_RS27370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5389c"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_234362883.1"
                     /sec_met_domain="APH (E-value: 1.9e-30, bitscore: 105.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDSPGPDRSPDLIDDDLVRGLLAEQFPRWADLPVSSVPLPGMD
                     NATFRLGDDLSVRLPRYERWIGQVEREQRWLPWLAPQLPLPVSAPLASGRPGLGYPFPW
                     SVYRWLEGEAATTENLADPVRTATELAGFIRALQRIDATGGPAPCLSNAFRGERVGTEC
                     DALAADSLVRAKIAKLDGIVDTDAVTAVWEAALAAPAWDRPPVWLHGDLATGNLLAVEG
                     HLSAVIDFGTLAVGDPACDLIPAWMFLPAKARETFRDAVDQDDATWARARGLALAGSLP
                     VPDDPFFAVPARVTASLRHLDAVLDDFRTYGG"
     misc_feature    19372..19386
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            19508..20422
                     /locus_tag="KY5_RS27375"
                     /old_locus_tag="KY5_5390"
     CDS             19508..20422
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602474.1"
                     /locus_tag="KY5_RS27375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_5390"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_098244720.1"
                     /transl_table=11
                     /translation="MDQNEAAAAAALAARFEEHRPRLNAVAYRMLGSLSESEDAVQETW
                     LRLSRSDSGAVENLGGWLTTVVGRMCLDMLRSRQSRREDSLDVSMDTHVPDPVVSRMDA
                     VADPEQEVLLADSVGLALLVVLETLAPAERLAFVLHDMFAVPFDEIAPVVERSTAATRQ
                     LASRARRRVQGSAPATDTGLAKQREVVEAWMAATKAGDFEALLELLDPDVVLRADTGEL
                     SSGLSKLVRGAATVAGQAAMFARFALVSRLVLVNGAPGLVAVPDGEPFSLASFTVVDGR
                     IVEINIIADRERLAGLGMPSFDD"
ORIGIN
        1 agtaatcact ccgcgaagca gtcactcctc gacgaggagc ttctcgcgca gttgcgcgag
       61 cgtgcgtgcg agcaggcgcg agacgtgcat ctgggagatg ccgacctcct gggcgatctg
      121 cgactgcgtc atgttgccga agaagcgcag gagcaggatg cgcttctcgc gtggcggcag
      181 gtcctccagg aggggcttga gcgattcgcg gtactcgacg ccctccaggg cctcgtcctc
      241 ggcgcccagc gtgtccgcca cggccggtga ctcgtcgtcc gtgtcgggga cgtccaggga
      301 cagcgtggag tacgcgttcg ccgactccag gccctccagg acctcctctt cggagatggc
      361 cagcttctcc gcgagctcgt gcacggtggg ggagcggccg tgcagctggg acagctcggc
      421 ggtcgccgtc gtcagcgcga gccgcagctc ctgaagacgc cggggcacgc ggaccgccca
      481 ccccttgtcg cggaagtgcc gcttgatctc gccgacgacc gtcggcgtcg cgtacgtgga
      541 gaactccacg ccgcgctccg ggtcgaagcg gtccaccgac ttgatcagac cgatcgtggc
      601 gacctgcgtg aggtcgtcga gcggctcgcc gcggttgcgg aagcggcggg ccaggtgctc
      661 gacgagcggc aggtgcatgc ggaccagctg attgcgcagc tccgcgtact cccgactgcc
      721 gtccttcagg gcgcgcaact cgatgaacat cgcgcgtgcg ccgctgcggt cctgtggatc
      781 gtgccggctg tgctcgtgct cgctcatgtt tcccgcccgt cgcccgccgc ctcggccgga
      841 gagcttcctg agcccctcct cggcggtcgg ctctgcctgc tccgacacat cggccactgt
      901 cagcggaccc ggcttccccg ggtcctccgg gtgcggcttg gcctgctgct cggggattcc
      961 ggtggtcata cggggcatcc cctccctgcc gccgacgggc agacctcgtg tgccacgctc
     1021 ttcgtcccgc accggcccgt ccccgttcct cacgccggcc cgggtcccgc gccgcgcttc
     1081 ttgtagaggc tgatcgagac ggtgttgtcc tcggcgacgg tggagtcgac ctggcccgcg
     1141 agggccgaca gcacagtcca ggcgaaggtg tcccgctcag gggcccggcc gtcggtcgtg
     1201 ggtgccgaga ccgtcacctc cagtgagtcg tcgacgagcc ggaacacgca gctgagcacg
     1261 gagccgggca cggcctgctg gagcaggatc gcgcaggcct cgtcgaccgc gatccggagg
     1321 tcctcgatct cgtcgagagt gaagtccaaa cgcgccgcga ggccggccgt cgccgtccgc
     1381 agcaccgaca ggtaggcgcc cgcagccgga aggcggacct ccacgaagtc ctgattcccg
     1441 ggctcgcctg cgatctggga caccctcacc tccaaggtgg tacaagcact ttcggggctc
     1501 cgggcctgcc gtgcagcggc gggtccggac tgcgtcacac gggtaacgca ccacgtcgtt
     1561 ctgcggtgac gctaccgcgc tccccagctc cgtgtcccgg ggaccccgcc ccgatgctgt
     1621 cactcatagt aagcctacgg gtacggacag tggctagggg tctgcgggcc caattgcaaa
     1681 gtacgggccg tcacttcaac aggggggtga cgtacccagg gctcagacga tcgaaccgtc
     1741 cacgaagcac cagcgccagc tctcgcccgg ttcgaaggta cgcatcaccg gatgtccggt
     1801 gtccttgaag tgcgccgtcg cgtgctggaa cggcgacgag tcgcagcagc ccacgtgccc
     1861 gcacagcagg cacaaccgca gttggacggg gtggctgccg accgcgaggc actcgaggca
     1921 cgtttcgctc agcggctcgg gttcggggtg cggcagcgct gtgacgtgcg agcactcgtt
     1981 catgatggcc aggttacgac gggaacgtgg aacgcggagg ggtctggcga tggacgtatt
     2041 gccgctggtg gcactgatcg cggcgagcgc ggtggtggca ggtgccgcgc gcaggactcc
     2101 ggtgcccgcg ccgctgctcc tggtcggggt ggggctcatc gccgcctacg tccccggagt
     2161 gccgggctac cacctcgatc cgcacgtcgt gctgccgctg atcctgccgc ccctgctgca
     2221 cacggccgcc ctggagagct cctatctgga cctgcgcgcc aacctcaggc cggtcgcgct
     2281 gctctcggtc ggttacgtcc tgttcgccac gctcgccgtc ggctggctcg cgtatctgct
     2341 catccccgac ctgccgctca ccgccgcgct cgtcctcggc gccgtcatcg cgcccccgga
     2401 cgcggtcgcg gcgaccgcca tcgcgcgccg ggtggggctg ccctcgcgga tcaccacgat
     2461 cctccagggc gagtccctgg tgaacgacgc gaccgcgatc accgcctaca aggtcgcgct
     2521 cgccgcggcc gtcggcgagg gcgcgagctg ggcgggcggc atccaggagt tcctggtggc
     2581 cgcggtcggc ggggtcggcg tcgggctgct cctgatggtg ccgatccact ggctgcgcac
     2641 ccacctgaag gaggcgatgc tgcagaacac gctgtcgctg ctcatcccct tcgtcgcgta
     2701 cgcggccgcg gaacaggtgg gcgcctccgg agtgctcgcc gtggtcgtcg tcgccctcta
     2761 cctggggcac cgctcctggc aggtcgactt cgagacgcgg ctccaggagg ccgcggtgtg
     2821 gcgggtcgtc gcgttcatcc tggagtcggc ggtcttcgcg ctcatcgggc tccagctgcc
     2881 cgtcgtgctc aagggcctcg gcgagtacag cgtcggacag gcggtctggt acgcggtcgg
     2941 ggtcttcgtc ttcgtcgtgc tcgtgcgctt cgtgtggtcg tatccggcga cctatctgcc
     3001 ccggtggctc tcgacgcgga tcaaggagcg cgaggacgac atggactggc ggcggccgct
     3061 gatcgtcagc tgggccggga tgcggggcgt ggtctcgctg gcgatcgcct tctcgatccc
     3121 gctcgtcatg gacgacgggg agcccttccc cgcgcgcaat cttgtcctgt ttctgacctt
     3181 caccacggtg atcggcacgc tcgtcgtgca aggactctcg ctgccgtggc tgatccgtgt
     3241 cctgaaactg ccgggccggg acgcgcaggc gcagaccctc gcggaggcgc aggcccagaa
     3301 cgccgcctcg caggccgcgg aggcccgggt ggaggaactc atgcgggacc gccgcaactg
     3361 ccttcctccg cccctccagg accgtctgcg gaccgttctg gagcggcgcc gcaactccgt
     3421 gtgggagcgg ctcggccaac cgaaccccgt cacgggggag tcggcggacg acacctaccg
     3481 caggctggcg cgcgaggcga tcgccgcgga gcgggaggtc ttcgtgagga tgcgggacga
     3541 gcggcgcatc gacgacgaga tgatgcggac gctgctgcgc aagctggacc tggaggaggc
     3601 ggcggcctac cgggaggtcg aggactgaga ggtgtcctcg cgcgcgccgg tgatcacggc
     3661 ggtgaggcgg gtcccggggc ggaaggcgcc ctcttcggag agggcggtca gcgcgtacag
     3721 gagcttggcc acgtagaggc gttccacgga gaggccgagt tcgtcgccgt gccggtcctc
     3781 gaagtcctcg gcgaaggcgc gcagttcggg ggtggtgcgg gcgtaaccgc cgcagtggaa
     3841 gcggtcgtcc aggtgccagt tggcggtcgg ggcgccgaac gtgccgcgtt gcagcgcgcg
     3901 tatctcgggg cccaggaagc cgcccttgag gaccggtatg ccaagcgccc gccggtccgg
     3961 gccgagcccg gcggccaggc ccgcgagggt gccgccggtg ccgcaggcca cggccgccac
     4021 gtcggtgctc tcgcgcagtt cctcgcccag cgcggtacag ccgcgtacgg ccagggagtt
     4081 gctgccgccc tccgggatca cgtacgcgtc gcgggcgccc gccgcgctca ggagcccggc
     4141 cagcgtcccg ggctcgtgct tgcggcgata cgtcgacctg tcgacgaagc gcagccgcat
     4201 gccgtcggac acgcaacggg tcagggacgg gttcagggga cgctcggcga gctcgtcgcc
     4261 gcgcaccacg ccgatcgtgg cgagcccgag gagacggccc gcggcggcgg tggcgcgcag
     4321 gtggttggag taggcgccgc cgaaggtgag cagggtgtcg tggcccgcgt cggtcgcggc
     4381 cgccaggttc aggacgagct tgcggaactt gttgccgggc aggtccgggt ggatcaggtc
     4441 gtcccgcttg agtcgcagcc gcacgccgtg gcgggtgaaa cggtcgtcgt cgacgtcctg
     4501 caacggcgac ggcagccggg gccgcagggc ggccggggcg ggggtgacgg gcggggtggg
     4561 acgcaccccg ccattgtccc ccgtggcacg ccgtccggca ggggagcccc ttgccgggcc
     4621 ctcggcgcgc tacttgaggc gctcttcgat gcggtccctc atccagtcca tggtgaaacc
     4681 gcgcgggtcc accttgcccg gctgccactc caggtggccg atgaccgagc gttccgtcca
     4741 gccgtggtgg cggcagatcg cggccgagac cttctcgatc gcctccagct gctcatcggg
     4801 ccaggggtcc tcgccgtcgc cgaggttctc gcactcgaag ccgtagaagt agcggttgcc
     4861 gtcggtgttc gcctcgttgt cgggcggcag ccgcttctcg gcgatgaccg cgcgcaggac
     4921 gtcgtcgtcg ccgagccccg cgtggttggc gcggccgtag ccgaccaggt ggacgtggcc
     4981 gtccttggtg atgacgccgt ggcagagcgg gcccggcagc gacgcgtagc cgtcgcgaca
     5041 gatctccacc gtgcgctggc tgcccgacgt caccgtgtgg tggatcacga cgccgtgcac
     5101 ggggccccag gggcccttgt ggttgcggtt gtggtgctcc cagtcgccta cctcgacgac
     5161 ggtcacgcct tcgtctcgca ggatgtccag gaacctgcca gcggacatgg gtggggccat
     5221 gaccgtctcc tttgcaaggc gcgacggccg ccggtcgcgg tccgcctcgt atgccctgct
     5281 tgtaccggaa ctccggtgcc cggaccagtt gttcggaagc aatccggtgg ctgttcgggc
     5341 accgtgcgag ccgatccggt caggtgccgt gcaggaagcc gtcgccgttc gccgcgacgt
     5401 ggctctccag ggcctggagt gcctgctggg tggcctgggg agagccggtg ccccggcgct
     5461 ccgcgtagta cgcggcgccc agcttcttca ggagggcgtc gcccgcgcgc ttctcctgga
     5521 cctcgtcgac cttctgcttg ccctgcgcga gggcgctctg cgcctgttcc ttggcgcgat
     5581 ccaggaagcc tgccattgct gtctcctgtc ggtcggtgcg gtgggtacgg gtggggccgg
     5641 tgccccgcgt gtggtctgaa cgggtgcgcg gatcttgtag ttccccgcac ccgtgcggtc
     5701 acgccgtgag cttgcgcatc aggcgtaccc cctgggacgg cttcatgtgc ggcagatacg
     5761 ccttgccgat cgcccgggtg atgttgggca gggccgccgg atccgggtag cacatgtaca
     5821 tcgggtggta cctgggctgg aacttcgcct tgaagttgag cagcgaacgg aatccgtaga
     5881 ccggttcgag gacgcggccc gcgtggtcca ggaggcgttg cagggcggcg ggcggctcgc
     5941 cggtgtcgga gcgggccagt ggcgctccgg agaggctcag gaactcggcg ccctcctcct
     6001 tgaagccgag tgccgccgac gcgatcagga actccatcga gccgcggaac ccgtcggagc
     6061 ggcgtcgcat gaagtccagg gtccagccca ccggacgcgg ctcggcgccg tccccgagcg
     6121 caccgacgtc tccgtagacc ggcatccagc tcgtgatgcc gtgcaccgtg cggtcctcgt
     6181 cgaccgcgag cagacagcgc acgtgcggat cgtcgagctc gtcgaggccg ccgagcgtga
     6241 agcccatctc cggcagcccc ttgtcggcca cccactcctc ggagatcgag cggatctggt
     6301 ccgtcagggc gatcggcgcg tcggggaagg agtgccactc ggcggtgatg ccgtccttct
     6361 tggccttgtt cagggccgtg cgcacgtcct gccacttctt gcccgtgaag gccagctccg
     6421 cgagcggtac gacggtgtcc tccgcgacct gcaccgcact ccagcccagc gcgtccgtac
     6481 gggccttggt ctcggcggtg acgctgtaga agcagggggt ccagccgcgt tcgtcgcagt
     6541 actcggcgaa gccgtcgatc gcgtccgcgc gcgcggacgc cgcgccgaac gggtcacccg
     6601 tggtgagcgc gaccgtggag tgcacccggt aggcgaccgc ggccctgccg tccgcggcga
     6661 accagtagtg gttgcccggc caggtcgtca gatacgagag cgtggcaccg ccgtgcgccg
     6721 cgagcagggc acgcgcgcgc gtggccgctt cgtcgtcggc gtgcgtcagg ggccgccgga
     6781 acgccacgaa gagggcgatc agggtgacca cccagaagag catcccgcag tactcgtaca
     6841 gcgcgagcgc ggtcccgccg accgggacgg gggcctggcc ctggaagaag aacggttcgt
     6901 agctgggcgg gaagaactgg gtgggcaggc ccgacaccag cttcgcgaac gtcgcctcgg
     6961 gcgtgaactg gtcgcgcacc gcgtagccga tgcccacgta ggcgaggcag gccagcagga
     7021 gcgcgccgcc gacggtcccc aggagccagg tcacggtggc cttggcgagg agctggtcga
     7081 aaagcctccg ggcgaggagg agcagcacga ggacgagcag cggcagcagc atctgctcga
     7141 cgaccgcctg gatcatcgcg gccttctggt cggcctgctc gctgccctcc aggacgtagc
     7201 ggtccgcgtg cgaggcgatg tcgctcagca ggtacgccat gagccccagc cacagcagtt
     7261 gcgcggccac cgtgatccgc caggagagcc gcagaccgcg ccgaagcccc tcggccagga
     7321 ccaggagcag cagcgggatg gcgatgccca tgagcatcgc gggggagccg tagaagtggt
     7381 cctcggcacg gacgcgggcg cactccgtgc ccgcgctcac gcaggcgtcc gcgatctcct
     7441 gggcgctcgg gccgcccgag acgtacaggt cgaggacgtt gaaggggccg agcgagtcct
     7501 tgtagagcgt ggcgacgagc gggccgatgg cggaggcggc caccaccagg gcgaccaaga
     7561 cccggccctc ggagtgcgag gcgtgcggca tccgcagccg gtgcgtctcg cggtgcgcga
     7621 gcgcgccgag ccctagaccg acgaccgtgc cgaacagtac gaggacgttc tggaggtggc
     7681 cgacgtacag cgcgagcatc agcgggaaga cgatcagggt cagctggagc ctgcgccgcc
     7741 acagggcgct gagccggaag ctgaggaagg cgccgaccgc gcaggcggcg atgccgggcg
     7801 tggcggtcag gtcccgcgcg aggccgtcga gccagtcctc gcccgccagc gagccgagct
     7861 cgacgacccc ggtgcccagc agcgagccga gcacctgccc gatgaacagc accacgccgg
     7921 tgcgcgccga ccccatgcgc tgttcggccg ccgagccgag cagcagcaac aacagcgtgg
     7981 atccgacgta gttgccgatc cccgaacacc acaggagcga cgtcagcggc gtccaccagc
     8041 ggccgcccgc gagtgcgggc acccccacgc ccacgtcgtt caggagcgcc tcgggcgggc
     8101 cgccgccgag gctgcccgtg aacgcgccca ccgcccacag cgcgacgacg acgaacacgg
     8161 tgacgggcgc gcggcgggcc ggttcgaagg cccggccgac ggcgcgcagc cagcggaccg
     8221 ggccccgctc acccggcggc gcgagcgggg ccgacggagc cgggtcctcc gcggcggctg
     8281 cggatgcctc ggaggtggtc atctcccgag cccaccagtc ggcggggtcc gacacatccc
     8341 gagctgggcc gaacgagtgg aaacgcccgc cctgcccagc cggggggaga tccattcccg
     8401 ctcgtttgtg taatggcgcc agcacgctcc gtgctggaag ggtgggcggc ctagaccacc
     8461 gcgggtactg gggagggcat agccaatgtc ggtaggcgaa gagatccgtg ccgagtcgga
     8521 gcagccgcag cagagtctcg gcacgtcggc ggcacggaat ctggccacca ccaccaagtc
     8581 ggcaccgcag atgcaggaga tcagctcccg ctggctgctg cggatgctgc catgggtgca
     8641 ggtacagggc ggtacgtacc gggtgaaccg aaggctgagc tactcggttg gcgacggccg
     8701 ggtgaccttc gtgaagacgg gggaccaggt ccaggtcatc cccgccgagc tcggtgagct
     8761 gcccgtgctg cgcgacttcg aggaccagga cgtgctcggg gagctcgcgc agcgctgccg
     8821 ccagcgtgaa ttcgccgcgg gtgaggtcct ggcctccttc ggcagcgcgg cggacgaggt
     8881 gttcctgctc gcgcacggcc gcgtcgagca gatcggcacg ggtccttacg gcgacgacac
     8941 ggtgctcggg acgctcgccg acggcgccta cttcggcgag caggcgctcg tcgacgccga
     9001 gtcgatctgg gagtacacca cgcgcgcggt gaccgcgtgc accgtcctga cgctgccccg
     9061 ccaggacctc gaacaggtcg ccgagcgctc ggagtcgctg cgcgcccacc tccagcagct
     9121 gcgcaccgtg cctgcgcagc gcaccaacgc gttcggtgaa gcggccatcg acctctcggc
     9181 gggccacgtc ggcgaagcgg tgctgcccgg cacgttcgtc gactacgaat cgtccccgcg
     9241 cgagtacgag ttgagcgtcg cccagaccgt gctgcgcatc cacacgcgcg tggccgacct
     9301 ctacaaccag ccgatgaacc agaccgagca ccagctgcgg ctgaccgtcg aggcgctcaa
     9361 ggagcgccag gagcacgagc tcatcaacaa ccgcgagttc ggactcctga acaactgcga
     9421 gtacgaccag cgccttcagc cgcacgacgg cgtgcccagc ccggacgacc tggacgagct
     9481 gctcagccgc aggcgcggat ccaagctctt cctcgcccac ccgcgcgcga tcgccgcgtt
     9541 cggccgcgag ctcaacaagc gcgggctcgt ccccgagacc atcgacgtgg gcggcacccg
     9601 gatcccgacc tggcgcgggg tgccgatcta cccgtgcaac aagatcccgg tcaccgaggc
     9661 gcggacgacg tccatcatct gcatgcgtac gggagaggac gagcagggcg tcgtcgggct
     9721 gcaccagacg ggcatccccg acgagatcga gccgagcctg tccgtgcggt tcatgggcat
     9781 cagcgagcag gcgatcatct cgtacctggt gtcgacctac tactccgccg cggtgctcgt
     9841 gcccgatgcg ctcggcgtac tggagaacgt cgagatcggc cgctggaggt gagagaacgg
     9901 ccgtggtcgt gttcgtgctc gacgcaccgg gtacatgcct ttcgtacgcg cccacaggcc
     9961 gaggaaaagc caccgtccac atccttttcg gggtgagtcc atgacggaca cgacggcagg
    10021 ttcggggttc cgtacgggtt cggaggcgga agcgggcgcg ggacgtgagg ccggtgagat
    10081 attggcggcc gcgcggctct gcgtcgatcc ggagcttcgc cgggccgtgg actcgctgcc
    10141 cgggtccatg cgccgggtcg cgctctacca cttcggttgg gagcacgcgg acggtacggc
    10201 cgcggccggc cacgcgggca aggccatcag gcccgcgctc gtgctcgccg cggtgcgggc
    10261 gctcggcggg gagcccgcga tggccgtgcg ggccgcggcg gccgtcgagt tgatccacaa
    10321 cttcacgctg ctgcacgacg acgtaatggg ccgcgacccc acgcgtcggc accggcccgc
    10381 cgcgtggacc gtgttcggtg acgccgacgc gatccttgcc ggggacgcct tgcaggcact
    10441 ggcgcagcgg ctgctcgccg aggaccccca tcccggggcc tcggtggcgg ccgcccgcct
    10501 tgcggcgtgc gtggtggagt tgtgcgcggg gcagcacgcc gactgggcgt tggagcggcg
    10561 cgggcccgac gaggtcacgc tcgacgagtg cctcgcgatg gccgaggcca ggacgggggc
    10621 gttgctcggg tgtgcgtgtg cgctgggggc ggtgtacgcg ggggcgggct gcgaggaggt
    10681 cgaggcgctc gacgggttcg ggcgcgaggc cgggctcgcg ttccagctca tcgacgacgt
    10741 catcgggatc tggggggatc cggggcgggc cgggaagccc gcgggggcgg atctcgcggc
    10801 ccggaggaag tcgttgcccg tggtggccgc gttggggtcg gggacggtgg ccgcggggga
    10861 gctggcggag ttgtacggca cgggggcggc gggatcgggt tcgggggagg gtgagttggc
    10921 gcgggtcgcc gtggccgtgg agagggccgg gggacgggac tgggcgcagg tgcacgcggc
    10981 ggaccggatg tcccgggcgg tggggcagtt ggcgcgggcc gtgcccgatc cggaggccgc
    11041 gggtgggttg ttggcgctcg cggagttcgt cactcgccgt acgtattgag ggtgcggctt
    11101 aaggtgcggc agcttgcggg tgcgccaggg gcgggtgcgt gacgcgtcgg ctcgttggac
    11161 gtcggctcgt tgggtgtcgc ccgccccgtg atgcgctcgt tgggtgtcgc ccgccccgtg
    11221 atgcgctcgt cccctcacac agccaagcag ccaagcagcc acgcatccac gcaggtacgc
    11281 aggtatgcat ccacacaggc acgcaatcac gcagccacgc ggccgtccgc ccacggaggt
    11341 gatcgcttag ggtgcaaccg ctggcgtgag cggtgtagtt gggtgaggtg tgggctgtgg
    11401 gtgtggcgat acggcgggcc ggggtggccg atcgggcgga catcgtccgg ctgctcgacg
    11461 aggcgttcct gcgggatccg gtgagcagtt gggtgtttcc cggcgaggag caccggcggc
    11521 gcatgcacgg cgggctgatg gcggccttct tcgatctcgc gctcgccgag gggtacgtcg
    11581 atgtgaccga ggacggcgat gccgccgccc tgtggtggtc ggtgcccggc ggggtggccg
    11641 agggggagga ggacgggccc gcgctgctgc gtgaggccgt ggacgccgag aacgaacgcg
    11701 tcgagctcat cgggcggttg acggacgcga tccacccgac cgaccgggcc cacgagtatc
    11761 tgcacatgat cgccgtgcgg ccggagcggc agggcgaagg gctcggcacg gagttggtca
    11821 acgccgtcct cgagcggtgc gaccgcgacg ggctgcacgc ctacctcgaa gcgagcaacg
    11881 cgcgcagccg cgacctgtac gcgcgactcg ggttcgtctt catggggacg gcgctggacc
    11941 tgcccgacgg cccgcgcatg tggccgatgt ggcgtgagcc gcgcggagtt gtgggcgggg
    12001 tcagcggctg acggcgcggg ggctgcctcg ctgttcgtgg ccggaatagc ctgaagccat
    12061 gggcagtgat gggggcgggg caggccccgg agtgcagggt gaacccgtgt gcgcgcgctg
    12121 tgggcagatc gtgggtacgg cgatccggcg gcgcaaagtg ctcggggtgt tcgtccccgt
    12181 gtgggggccg ggaccgtgcc gtaacccgga gtgtgcggcg tacgtcgtgg acgaggagag
    12241 cggggaggcc gccgtccggc gtcgcgggca cgggcattcc cactcgcggg tcaggtccag
    12301 gggccgacgg gacgccgagg gccccggggt gtccgggggc gtgggttcgt ccggcgggga
    12361 ggacgcgccg gacgtcggga gtgccgatgc cggggccgcc gggggccgtt gacacggaag
    12421 ggcggtgggt tgttcgcctt cttgcgcctt cttgcgcctt cttgcgcctt cattgttcta
    12481 gtaggatgcg aacaagggag gttttcatat gtcgcaggtt gaggggttcg ttggagattc
    12541 cggtcgcggg agtcgtcgcg ccgatgctcg tcttgtctcg ctcgccgtcc tgcctttcgt
    12601 gctcgcgttc ctcgtggagt tggcggtgta cgccgcgctg agggaccggc tgcccgggcg
    12661 gatggccagt cacttcggtc ccgacggcgc cgccgacggg tacgtcgggc ggggcgcctt
    12721 tctcgccgtg ggcggcgggc tgttcgtggg gctcggcgcg gtgggcgcgt tcgtggcgct
    12781 gaagagcgga tatcgcgcgt accggcgtgg agtggtgggg ctgctggccg gttgctgggc
    12841 gaccgccgcg ttcctcgggt ggccgatgac ggcgagcctc gtcgccaacc gtgacctcgc
    12901 ggacggcgcg tcggcccggt tcccgctgtg gcagttggcc gtgaccgtcg gcgtcgccgc
    12961 ggtggcggcg gggatcgggg ccctcctcgg gctcgcgctg gcccggcgta cggcgctgcc
    13021 ggacgtgcac gggggcggcg ccgtgcggga caccgatgcc gcgcggctcg ggctcggcga
    13081 tgcggagcag gccgggtggg tgcgcaggac gggctcgccg tggctcttcg ggctcggtgt
    13141 cgcgacggcc ggggcggggg tcggcctggc gtgggtgcag cgggagtggg tggccccgct
    13201 ctccctggtc gcggccgggc tgctcgtcgc cgcgttcgcc aggccctgcg tcgccgtcga
    13261 ccggcgcggt ctcaccgtct cgccgagcgt ggtgccctgg ccgcgcgtac ggctgccgct
    13321 cgaccggatg gagcgggcgg acagcgagta cgtcaacgcc gttggcgact acgggggttg
    13381 gggctaccgg gtgtggccag ggcggtccgg gatcatcctc aggtccggcg aggcgctggt
    13441 cgtgcggcgc acgagtggca gggtgttcgc ggtgaccgtg gaggactcgg ccacggctgc
    13501 cgcgctcctc aacaccctgg tcgaacgacg gaccgcggag cgctgacgac atgttgttcc
    13561 ggatcgatac gacatcggcc gtgccgctcg gcgaccagat cgcggcctgc gcgcgccgcg
    13621 ccgtcgtcga cggcagcgtc ggccccgggg agcggctgcc cgccgcccgg atgctcgcgg
    13681 gatcgctcgg cgtgaacgtc cacaccgtgc tccgcggcta ccagcgcctg cgggacgagg
    13741 ggctgatcga gctccgcagg gggcggggtg ccatcgtcgc cgacagcgcg gcggcgcggg
    13801 cccgcgccca actcgtggag cgggtgcggg agttcgtatc ggacgcgctc gacctcgggc
    13861 tttccgatga cgaggttctc tcgatggtgg gggccgccct gaaggcgtga ggccgtccgg
    13921 gggcccggct ccggcggggg tagggtccca cggtcggtga tgtcgcccgg ggaggggttc
    13981 gatgagggcg cggtggggtg tactcgctct ggtgggggcg gtgttggcgg tgttggcggg
    14041 gtgtggggcc gggggcggtc ctggtggcgg ggtctcaggt cgcgagccgg aggacggcga
    14101 gccgcgcgtg aggaccagcg cggacgtccc cgaactcccc ctggatgcct atgagttgag
    14161 cgaccgcgac aaccgccgca tgggacaggc gaagtcgcgt ctcgtgcagc ggtgcatgcg
    14221 ctcctacggc ttcgccgact tccccctcaa cccccggccg gagccgtttc cgaagatggg
    14281 gtcggccttc acctcgacgg tggtctcgat ctccccgtac gggacgctgg acctcggcca
    14341 cgcccgccgt tgggggtacg gcttcgaccc ggacgccacg ttcacgccga aggccgaggg
    14401 gccggagggg cgggccgtga cgcagcggga atacgaggtg ctgaacgact tcggcgaggc
    14461 cgggcggacg gccgccgtgg tgaacggccg caaggtgccc aacggcggct gcaccgggga
    14521 gagttcgcgt cggctgctgg gcgacgagac gaagcgctcg cgcctgtggg cgtatgtcga
    14581 cgagcgcgcc gaggagatcg acaaggtcgt cgccaaggat ccgagggtgc gcaggatctt
    14641 tggcgagtgg tcgcgctgcg ttcaggacaa gggctacaag gcgtacgaaa gtccgcgcga
    14701 cgccttccgt gacaaggcgt ggcgcgacgg ggccccggac ggcaacaccg cacgtagcca
    14761 gcgggagttg gggacggccg tcgccgacgt cgagtgcaac aggaagctga acgtcgccgg
    14821 ggtgtggtgg gtcgtcagcg acgaggagca gcgcgccgac atccgtcgcc acgcggcgcg
    14881 gtacgaggcc gtgcgcgcgg accaggagcg gctgcggggg accctgcgcg aggtgctcgg
    14941 cgagaagtga gggccgcggg gtcctcagtg ccgccgtctt tcgcggtggc gggcgaccgc
    15001 gtcgttgttc gcacagcgca ccgagcagta cgcgcggcgg ccgttgcggg acgtgtccac
    15061 gaaggcggtg ccgcagggcg tgcgggcgca gcggcccagg cggtgggcct cggcgaagca
    15121 gacgacgtag gcgaggcccg ccgcagtgag ggcgcggacg tgggcggccg gatccgcggc
    15181 gggggcgctg tagtggaagt gcgggtggcc gtcgtgcagg gagatgcggg ggctgctgga
    15241 ggcgtgcgcc agcagggcgt tgacgcgggc gcagcggcgg gggaggtcct gcggtccgaa
    15301 acactccgcg aggcgtacgg cccagtcgcg gaggtcggcc tcctgggcgg tggtgagggc
    15361 gtggtccgtg acgccgcgcg cggcgaggag cggggccaga gggggtgcgg gggcgaggga
    15421 gttgaccagg tcggcggcga gcagggccgc ctcgcccccg taatggttga aatgcataag
    15481 ggcatgacat cacgctgacg ggcgtgagag atgtggcgcg ggactcgggg agtggcgagg
    15541 cggcgaaggg ctcggcgggg ggtgagggga cggagagctc ggggaggggt gaggcgacag
    15601 ggggcttggg gagaagcgag gcggtgaggg tctctggaag gggtgaggcg gtagggggct
    15661 cggggagagg cgaggcggca gagggccccg ggcgaggtaa ggcggcgagt ggctcacgga
    15721 gtggtgaggc ggcagagggc ccggggaggg gtgaggcggc gaggggctca ggaaggagcg
    15781 aggcggcgag tggctcgggg agaggcgagg cggtaggggg cctgtgggga agcgaggcgg
    15841 tgagggtctc aggaaggggt gaggtggtag gtggcttgcg gagaggtgag gtggcacagg
    15901 cccccgggcg aggtaaggcg gcgagtggct cggggagagg cgaggcagta aggggctcgc
    15961 ggagtggtgt ggtggcagag ggctcgggga ggggtgaggc ggcgagtggc ttggggaagg
    16021 gcgcggtgcg gggtgctcgc gttgctgtcg ggctcgtgtt tgtgcagatc gtcagcctgc
    16081 agtgcgggtc cgcgctggcc aaggggacgt acggtcaggt cgggcccaca gcgctcgccg
    16141 ggatgcggct cgggttcgcc gcgctcgtcc tgtggaccgt ggtccggcca cggctctcgc
    16201 ggctttcggc cgcgcagtgg cgggccgcgg ccgggctcgg tgtcgtcttc gccgggatga
    16261 actccgcgta cttccaggcg atccgccacc tcccgctggg cgtcgcggcg accctcgaac
    16321 tcctcggccc gctggccctc gcgctcgcgc tgtcccgcag ggccgcgcac ctcctgtccg
    16381 ggctgctcgc gctcgccggg gtgctgttgc tcgcggtgcc gggtggtgcg ctgcccggcg
    16441 tcggcgtcat ggcgggggcg gtggccgcgc tgtgcagggc gggttacgtg gtcctcaacc
    16501 agcgggtggg gcggctcttt tccggctggg acgggctcac cgtggcgctg ggcatcgggg
    16561 cgtgcctgct ggtgccggtc gcgggggcgg tcgacggacg gtccgtcgtc gagcatccgg
    16621 cgctgctcgg caccgggttc ctggtcgcgc tgctctcgtc gctgatcccg tactgcctgg
    16681 acatgctcgc cctgcgccgc atcggcgcac gagccttcgg cgtactgctc gcgctggggc
    16741 ccgcggtggg caccggcgtg ggctacgccg ccctcggcga gcggctcggg ctccgggagt
    16801 acgcggcggt ggcgctggtc gtcgcggcgg cggcgtggtc cgtgcggacg gcggagtgag
    16861 ggcgcgggct tgaaccaccc ggttccaggg gcccggacgc cgggcccccg agccctcacc
    16921 cggaactacc cccgctccgc ctccgcctcc accgccacct ccaccaaagc cctccgcaac
    16981 gccgccgcga actcctcatc cgtgccgagg agttcatcgg cgtacccccg cacggacccg
    17041 taccgctcgg tcagcgccgc gaggaacagg gtcatgacct ccgagggggc cttgccgtag
    17101 cccggccaga tcccggtggc ctcggggtgg gtcgttcgcc agtcggcgag caggcggtcc
    17161 gatgcgaggc cggtgagggc gaagtcctcg acgatcgcgt cctcggggac gccgacgagc
    17221 gcgaggacca gggcggcgat caggccggtg cggtccttgc cggaggcgca gtggaagacg
    17281 aggggctcct tcgccgccgc cgatgccgcg atgacgtcga gcacggccct gatctccttg
    17341 acgccgtcgt gcgccacctc cacgtaccgc tcggcgaggt acggtcctgg ctcgacgtcc
    17401 gggccgagcg cggcctggtc gtagggccgg tgctcgatgc tcagctggtg gtaggcgagt
    17461 ccgggcagct ccggtacccg gcccttggcg gcgatctccc agtcgtagcg cagatcgacg
    17521 accgcgcgcg gcccgagtgc gcaaaagcgt gcccagtccg cgcgctccgc ctcgtccgcc
    17581 ccgtcgtcgg cccgcagctt gccgagcgag tcggcgcggt acagcagccc cgaccgcacg
    17641 aggcccccgt cggcggtgcg caggcccccc aggtcgcgga cgttgtgcag gcgcgcgaac
    17701 ggtatgtgcc tgtcgttcgt gtctctgtcg tgcgtgtctc tgtcgtgtcg gttcacgtaa
    17761 cgggacctta gagggcggga gggccggacc tcgcccccgt gatagacaca tgcgatgaag
    17821 atctccggcc gggcgttcga cgccgtactg agcgacctcg acggcgtgat ccgcttctac
    17881 gacatggcgg aactggagca gtcggagcgc gcggcgggcc tcgccgtggg cagtaccgcc
    17941 gagatcgcct tcgcgcccga gaccgacctg cccctgatgc gcggcgagat caccaaggac
    18001 cagtggaccg aggcgatcgc gcacgggctc gccgaccgcg tgccccacga gcgcggccgg
    18061 gaactcgcga cgacgctcgc cgaggcgaag ttccgcgccg acgaggtggt cgtgggcatg
    18121 ctgcggcagg cccgtgccgc cggtctgccg gtgctgctcg tcaccaacgc gacgccgtgg
    18181 ctggccgacg atctcgcgct gctcggtctc accgggccca ccgggctcgt ggacgacgtg
    18241 atcagcagcg ccgacctcgg catcgtcaag ccggaccgtc gcatctacga ggtggcggcg
    18301 gagcgggccg gggtcgcccc ggcccgctgc ctcttcgtcg acgaccgcca ggagaacgtg
    18361 gacgcggccg ccgcgctcgg catgaccggg ctgctctacc gcgaccacgc ggatctgcgc
    18421 gcggtgctgg agcccgcgct ccggaccggg gcgcgggcgc gtgcgcgggg cgactaaccc
    18481 ccgtacgtcc tgaagtcgtc gagcaccgcg tccagatgcc gcagcgacgc ggtcacccgc
    18541 gcgggaaccg cgaagaacgg atcgtcgggg accggcagcg acccggcgag cgccaggccg
    18601 cgcgcccgtg cccacgtcgc gtcgtcctgg tcgaccgcgt cgcggaacgt ctcccgcgcc
    18661 tttgcgggca ggaacatcca ggccgggatc agatcgcagg ccggatcgcc caccgcgagc
    18721 gtgccgaagt cgatgaccgc gctcaggtgt ccctccaccg cgaggaggtt gccggtcgcg
    18781 aggtcgccgt gcagccagac cgggggacgg tcccacgcgg gcgcggcgag cgcggcctcc
    18841 cacaccgccg tcacggcgtc cgtgtcgacg atcccgtcca gcttggcgat cttcgcgcgt
    18901 acgagggagt cggcggccag cgcatcgcac tcggtgccca cgcgctcgcc ccggaaggcg
    18961 ttgctcaggc agggagcagg gccaccggtc gcgtcgatcc tctgcaacgc cctgatgaat
    19021 ccggccagtt cggtggccgt gcgcaccggg tccgcgaggt tctcggtggt cgctgcctcg
    19081 ccctccagcc agcggtagac cgaccacggg aaggggtagc cgaggccggg ccttcccgac
    19141 gcgagcggtg cggagacggg gaggggcagt tgcggggcca gccacggcag ccaccgctgt
    19201 tcgcgttcga cctgcccgat ccagcgctcg tagcggggca gccggaccga gaggtcgtcg
    19261 ccgagccgga acgtcgcgtt gtccatcccg ggcagcggca cggacgagac gggcaggtcc
    19321 gcccaccgcg ggaactgctc ggcgagcagg ccgcggacga ggtcgtcgtc gatcaggtcg
    19381 ggcgatcggt cagggccggg cgagtcggtc gacaagagga actcctggtg agagcagggg
    19441 tgaacgtcac accggaacgg tccggtccgt cattgtcatg acggaccgcg acgagagaat
    19501 gtgacgcatg gaccagaacg aagccgctgc cgccgccgcc ctcgcggccc ggttcgagga
    19561 gcacaggccc cgcctgaacg ccgtcgcgta ccgcatgctc ggctccctga gcgagtccga
    19621 ggacgccgtc caggagacgt ggctgcggct cagccgctcc gactccggtg cggtggagaa
    19681 cctcggcggc tggctgacga ccgtcgtggg gcggatgtgt ctcgacatgc tgcgctcgcg
    19741 gcagtcccgg cgcgaggact ccctggacgt ctccatggac acgcacgtgc cggacccggt
    19801 ggtgagccgc atggacgcgg tggccgatcc cgagcaggag gtgctgctcg ccgactcggt
    19861 cggcctcgcc ctcctcgtcg tactggagac cctcgcgccc gccgaacggc tcgcgttcgt
    19921 gctgcacgac atgttcgccg tgcccttcga cgagatcgcg cccgtggtgg agcgctcgac
    19981 ggccgcgacc cggcaacttg ccagcagggc ccgccgccga gtgcagggct cggcgcccgc
    20041 cacggacacc ggcctcgcca agcagcgcga ggtcgtcgag gcgtggatgg ccgcgacgaa
    20101 ggccggcgac ttcgaggcgc tgctcgaact cctcgacccg gacgtggtgt tgcgcgcgga
    20161 caccggcgaa ctgtcgtcgg gcctgtccaa gctggtgcgg ggcgcggcga cggtggccgg
    20221 gcaggcggcg atgttcgcgc ggttcgcgct ggtctcgcgc ctggtcctgg tcaacggggc
    20281 gccggggctc gtcgccgtgc cggacggcga gccgttctcc ctcgcgtcgt tcacggtcgt
    20341 ggacggcagg atcgtggaga tcaacatcat cgcggaccgg gagcggctgg cggggctcgg
    20401 catgccgtcg ttcgacgact gaggaggccg tacgacggcg gggagtcggt gtcatgcgac
    20461 cggctcctcc cggcccccgc cggacgtgcg gcgcaccacc cgcagcaggt actccttgcg
    20521 gctcagcggg tcgtgatccg tccgggcgcg ggtgggcggg gcgccccgca cgggctcgta
    20581 gtggtcgaac gcggactccc actcgccctc gccgcgcgtg agtccgggca gcatctgctc
    20641 cagggcgtgc acctgcttcg cggggatgtc cccctccagt acgtacgaag ctccgctcgt
    20701 ggtcggcgtg tgcggcaccg cccgcagtcg cgtgagcgcg ggcaggaccg cgccgaacgt
    20761 gtcgccgggc acgtcgatcc tgaagcggtg catcggctcg tgcaccaccg tgcccgcccg
    20821 gcgcagcgcg tccatcagga ccagcggcgt caggttcctg aagtcgcccg ccgtgctcga
    20881 catgctcttg tcgaaggtgc cgtgcgcgtg gctctgcctc ggccagtagc cgcagtgcgt
    20941 catcgtgacc gtgcagtcgg gcacgcgcca gccgtacagg ccctggtgca gggtctccct
    21001 gacggtctcc tcgaccgcgc ggaagaacgc gtacggcatc gcgccgagtt cgacgccgag
    21061 ccggaactcc accccggcgc cgaccggcg
//
