LOCUS       NZ_CP022685            24199 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5771671
            Orig. end                         :: 5795870
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24199
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="26"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24199
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24199
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14199](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14199
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            443..880
                     /locus_tag="KY5_RS25260"
                     /old_locus_tag="KY5_4968"
     CDS             443..880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998614.1"
                     /locus_tag="KY5_RS25260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4968"
                     /product="hypothetical protein"
                     /protein_id="WP_199843228.1"
                     /transl_table=11
                     /translation="MDDEGRQVPRAAEMRGRARGFVAQVTSRNRLPLDFSVASLRVVDF
                     LIEGLRKGGRERSEIAGALFGLGAYVGEVLVRRAGAMWIDLDKEQREFFGQSVGVRMPD
                     GRVWNPLGKVVNCLERGGMDGSESSLQIFYLTLPGRVGHAA"
     gene            1007..1648
                     /locus_tag="KY5_RS25265"
                     /old_locus_tag="KY5_4969"
     CDS             1007..1648
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190279.1"
                     /locus_tag="KY5_RS25265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4969"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_098244365.1"
                     /transl_table=11
                     /translation="MGQGGVHRHAAGSDEELTRALVAAGAGDEAAFAVVYRCVHPGLLR
                     YLRGLVREDAEDVASETWLQIVRDLHRFRGGGGEFRRWTATVARHRAIDHLRRQRSRPR
                     PAHLSQEVFDLPGTDDTAGQVLEALSTAHVLRLVSALPPDQGEAVLLRVVVGLDAPAAA
                     RVLGKRPSAVRSAAFRGLRRLAGELDAEAPTRRRAAGGEYAVRRVRRAAC"
     gene            1768..3978
                     /locus_tag="KY5_RS25270"
                     /old_locus_tag="KY5_4970"
     CDS             1768..3978
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986051.1"
                     /locus_tag="KY5_RS25270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4970"
                     /product="hypothetical protein"
                     /protein_id="WP_098244366.1"
                     /transl_table=11
                     /translation="MPEELGFDELLADGGLIARLLGRTAAGRRRDLLYGDDLPVVLLVG
                     GPGMGKGRLLRCVRGRFGPRVPTAYVDCALTGCREQAEERPRSRSEVTEVLGKIASQYV
                     DWRGDGGGIPVPRLYAGLAAVAASDPLAPATRLVDEVGRLDGLLPPGSFWRGVLKGTAK
                     NYVGFLLGLVTHPLVGPFINALLDGLLARTSKEGRAALTACYGDYPGAGGQPLVGLRSL
                     ADDFQQGGEARRIAEGFLLRALRQDIDAAYGNVRGQLTRVGRPALLLDHADGALGRRLL
                     KPVLEDRERGHHDRLVIIATARREDGGRFLHRAGSDHDDMATWRPFMGALPAWSRPPDA
                     VPDHAPLWRGVLRVRMPVLTRDQQKDELSRLRGGREQPDNAVRLRIHSGVHRLSGGRPL
                     FVTRLGEATAAASFPTPEECTDWAILDARVPAGEDEQGRPVADRPVADVLVDELVGREL
                     PEELPPEHRGHWLDLLTHLSVAHDVECAQTLVRAVQEDRSERLNAYRIAELLEDTGWPR
                     CPRHFIGDLGLRRLLTRRLYRLRDGGAAWHADHALLQGHYRDLGDHHADALFVTAGAHR
                     MHHLLASDGADLVTRYLAGTFLTRPAAEWCEELLAVADAALIGADDDRYARALGETQVR
                     GDTLRRRVDRLLHAVWLTEDRIQPLEETVPTVLRGPLRELSEELSKIADEAVRDQGPEG
                     ADVARAADGAALLIRMARDWGDRAEDKQPLQRCVCTEHIGFG"
     gene            4014..5612
                     /locus_tag="KY5_RS25275"
                     /old_locus_tag="KY5_4971"
     CDS             4014..5612
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986050.1"
                     /locus_tag="KY5_RS25275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4971"
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_234362856.1"
                     /transl_table=11
                     /translation="MRQFGNWLYNTFWANWMRRILTLLGLAAAGVLLWVFLPPIGAPES
                     CASGVEKHGGECIGVNGSGYDFGTPEIREVARAIAKENEKFVGDKPHVTVALMLPLQPD
                     IAAERVQLRSEIQGAYLAQYRSNRNESTPLMRLVLANPGDGYAQQAAVVDQLGEMSRDK
                     SDNLRAVTGFNLSLDATEKAISRLTNELHIPVLASRVSADELANPEKSTGKVPYPGLAR
                     IIPTNRQQADALASFHGRLKDEDTVLVKDTRPHDIYNDSLAKAFSRTEPGPPGPKDQPF
                     ESPSITDPGDTGNDFTLIAQNICQSSARYVYFAGRPVHLRLFALKLADVQCKGKKYTIV
                     SGSGSATLNRYMKGDDWAKLRGGDSKEPIVTVQYAAPGHPAAWDTELGREGAAKKRPDY
                     FTEPQKELRELRLLIGRGSAGHIGDVRLDDSRTMLVHDGVRTIAKAVLLANAQTEGTVP
                     PLKRVSDMWQRIEATNRVVGTSGLICLTNAGNAYDKPVAVVELNPTTKKLEFVGIGWPK
                     GKPQPADCRVPSGTG"
     gene            complement(5638..6987)
                     /locus_tag="KY5_RS25280"
                     /old_locus_tag="KY5_4972c"
     CDS             complement(5638..6987)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024907.4"
                     /locus_tag="KY5_RS25280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4972c"
                     /product="FG-GAP-like repeat-containing protein"
                     /protein_id="WP_098247472.1"
                     /transl_table=11
                     /translation="MAEPGAGKNSAIPTGDFNRDGITDLIAGTPKASSSRGRVTVVPGG
                     LEGPVAASKISLTQASEGVPGASETGDDWGAATAWGDLNADGYADLVIGAPGEDDAAGN
                     TDRGAVTMLYGPKFTSGTDMQLADDFHYKGARFGSAVASGDFNADGKADVFATATGTGG
                     SWAARLDPEHESGGSLTSGDTAIAYADAASGDFNRDGYADVALTYRDQAGKGKVAWFRG
                     GRSGLSRVGVLSVPGGRSVAVGDVNGNGYDDLVIGQPYTAESGAHAGGQVTVVPGTSTG
                     LTSTGAKTVHQATSGVPGAAEAGDAMGWSVAAGDYNADGYADVLTGAPGEDITRSGTAR
                     EDAGTSLLLKGSSSGLTGTGAKAFSQDEPGVPGSTETGDRLGSSATLAHLSGSARADLA
                     IGVEGEDAGDGTILQLDSGSSGVPGSSGVYYGRTDLGTPAGARLGQALTP"
     gene            7338..8201
                     /locus_tag="KY5_RS25285"
                     /old_locus_tag="KY5_4973"
     CDS             7338..8201
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS25285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_4973"
                     /product="hypothetical protein"
                     /protein_id="WP_159072595.1"
                     /transl_table=11
                     /translation="MYGRTGTGTGTGRRWVRAAALSLAVGAVAGVLTSCGTHDRAVSYS
                     GGTLEKVTPENERRGKEISVEAMGLFKDVGSLRLAVDRTSARGRQKVSLHMDRDSNCTG
                     TFDAGPTQRGDLIMIEGRATYVRFSDRSLQEIRELAIRRGPEIAARARERTALARGKYL
                     KIPTGGAVGSAAMPVDSCDLDKITRQMPGGPGPDDVIKAQGPTRRYGEDVIPLVEHGNG
                     ETTVYVAAHGKPYVLGLEAAENGETMRMRMSDYDEPVEAVAPAAAQTIDISEVSGGTGG
                     GSLFEV"
     misc_feature    complement(8271..8286)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            8358..8984
                     /locus_tag="KY5_RS25290"
                     /old_locus_tag="KY5_4974"
     CDS             8358..8984
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015658291.1"
                     /locus_tag="KY5_RS25290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4974"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_098244368.1"
                     /transl_table=11
                     /translation="MGQGGRSRRARAHDEELGRAIAAAQQGDEAAFAIAYRLVQPGLVG
                     YLRGLVGTEGETAEDVAAEAWLEIARDLGRFRGDGAGFRGWTATIARHRAFDHLRRQRT
                     RPRPAAPEQDLLELPGPHDTPEQALEAISTRRVLDLIGELPRDQAEAVLLRVVVGLDGP
                     ATARVLGKRPGAVRTAAHRGLRRLGERLGPDGAADEGPGTLGESR"
     misc_feature    complement(9303..9315)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            9408..9935
                     /locus_tag="KY5_RS25295"
                     /old_locus_tag="KY5_4975"
     CDS             9408..9935
                     /EC_number="1.17.7.3"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016438.4"
                     /locus_tag="KY5_RS25295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4975"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_098244369.1"
                     /transl_table=11
                     /translation="MATVVADSVVPVVPLLKRVVGPGALRALPEDQLPGLAGEIRRFLV
                     AEGIGDTNRVSLSADPVEQVKAGCRIPRTPGLRPRKLEIAACPGRGGRPRLQADIHKPV
                     SQVEAAFDGFPHPLRVSYGNGQVFCHGEVLRTAPASAFVETQLGGASRLPDTSSGSTPR
                     RMVNSSEAGEQT"
     gene            10001..11068
                     /locus_tag="KY5_RS25300"
                     /old_locus_tag="KY5_4976"
     CDS             10001..11068
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349428.1"
                     /locus_tag="KY5_RS25300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4976"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_234362857.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.9e-50, bitscore:
                     168.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPARIRHQVDAVLGAFIHHKKAAAREQGLPVEAPQALDDFLAAG
                     GKRLRPLLCVLGWHTTGSSSGGGLAQAVQVGAALEMFHAFCLIHDDIMDHSDTRRGRPT
                     VHRALAARHRAGHDAVLAKDIGTSAAILAGDLALLWSDELLRAPDTGLGPAQLEQVAPL
                     IDLMRGEVLHGQYLDLISTGRPSPDTGPALAIIRYKTAKYTCERPLHIGAALAGADARF
                     LDALSAFALPLGEAFQLRDDLLGVFGHQAETGKPTFDDLREGKHTVLISFALKAADDTQ
                     ARLLRTLYGNARLDEDDTDTVRAVLRATGADQAVEHMITNRYEQALAALEGLSLPREVH
                     HQLRSLADKTVWRTS"
     gene            11065..12054
                     /locus_tag="KY5_RS25305"
                     /old_locus_tag="KY5_4977"
     CDS             11065..12054
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="KY5_RS25305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4977"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_098244370.1"
                     /transl_table=11
                     /translation="MTAAVRSGNGDRHSGYDATWFAAAHSKNLKHQQIVNTVVCEKKVT
                     LYRTADGVVHAINPVCPHLGASLGHGRVEGDNIRCPFHGLAFNPEGRCVEVPWGAPPIR
                     PSVQHYRVHENNGFIYVWVSETEPAWTPLHLDRSPFTYAVTWEATISASPRDMVENAPD
                     YQHFAALHTMEAPRRTAPTVFEKHVMSIRLNAAGFWVNYPTLASLNAEGTGLIHAHVTM
                     PRTAFRLLEIVTQTPADQGTSVLRVATYANATTFLKGAARKGADRLVSHLAHWGATHQM
                     KRDIFIWAHRVYPEHAHLTKGEEDIAALRRWMRQFDEAAPQPDPPPAA"
     gene            12187..13140
                     /locus_tag="KY5_RS25310"
                     /old_locus_tag="KY5_4978"
     CDS             12187..13140
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="KY5_RS25310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4978"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_159072596.1"
                     /transl_table=11
                     /translation="MTMQRHTYPWGWYPVAFSRDVPSGKVITSKLADSEVVVYRTADGQ
                     AHVILPTCPHLGAHLGGGHVEGQLIVCPFHAFGFAPDGTCARTGYNTTPPHNARVGTFP
                     TQEANGFVFAWYHEAATAPAWRIEQVDLKGFGYGYRNQNTFRGNQIDLLENGVDLGHFQ
                     VVHANQAKIVNGHPIEDDFRYVIDLELTGFYRNIPTYVRAEMYGLGYAVVSLKMPKFAV
                     SAYEIIGYTPEGSGLITLRRTTVTRCGSAPGNPAGRHILRVVSTLVGYVVMRLSTVQGN
                     NDIRIWDRRVFIERPKLAQGDGPIMPARKWAEKFHH"
     gene            13192..14199
                     /locus_tag="KY5_RS25315"
                     /old_locus_tag="KY5_4979"
     CDS             13192..14199
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="KY5_RS25315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4979"
                     /product="terpene synthase family protein"
                     /protein_id="WP_098244372.1"
                     /sec_met_domain="T1TS (E-value: 4.4e-51, bitscore: 173.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRTEFDIPGISATSPHVQAAREHLLKWMKGYDLLPSDSRTQQLG
                     SEDVALLTAMGYPWAGSEELNILTDYLAVTWVIDDGLDTKFGREPHHVIKLVEQLCAVL
                     DFHAVGPAPVVVDAFHDVWKRSVEVASPHWQEHASHTWRAYFWGQAWETINRYRAMNAL
                     DLENYVSLWNICSGGAVWFEYVELGHEEFPPAWFHSPEVQNLRRAANGVALAVDDLASL
                     EKEESDDDEHNFIKVMINAHGYSREDAIAKAVAWGQEQADLMRRCYARLQAYAEQRVGL
                     DGTDIEKCLRAADAVLAGTRGYHDWALISPRYGSHGIQVRGDGIDEPLRVRGLF"
     misc_feature    15295..15308
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.68"
                     /tool="antismash"
     misc_feature    15303..15323
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.79"
                     /tool="antismash"
     misc_feature    15385..15398
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.75"
                     /tool="antismash"
     misc_feature    15439..15455
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.22"
                     /tool="antismash"
     misc_feature    15450..15465
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            15606..16226
                     /locus_tag="KY5_RS25320"
                     /old_locus_tag="KY5_4980"
     CDS             15606..16226
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS25320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_4980"
                     /product="hypothetical protein"
                     /protein_id="WP_098244373.1"
                     /transl_table=11
                     /translation="MNRHSSRSMRLVTSAILTAPLLVVLPGADLAQAQAPACGGTRDAY
                     VGSTYRGTTKTTGSLNPSLLPPILNPHRLDTPSTPLRAAAGINAEAELVVKFTKDARGE
                     YWANTTADGKVTSRSGYTLNLTGAPKVEFNAKMHEPVLHEVWQTVKGELKHIDKLDSVG
                     KYIYGYALAAQNCPSGSQTPTVLASTEDNGFGLRTTTRLTRQG"
     gene            16399..16635
                     /locus_tag="KY5_RS25325"
                     /old_locus_tag="KY5_4981"
     CDS             16399..16635
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850196.1"
                     /locus_tag="KY5_RS25325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4981"
                     /product="hypothetical protein"
                     /protein_id="WP_098244374.1"
                     /transl_table=11
                     /translation="MKKIISVAGLALAVACLAAPAHADDGDNFGPGINAANNWNFTAAA
                     VCFQELAVVPVGGAWNGNTLNHCVNGNVLNHAK"
     misc_feature    16408..16422
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(17184..17306)
                     /locus_tag="KY5_RS42965"
     CDS             complement(17184..17306)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS42965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_267894293.1"
                     /transl_table=11
                     /translation="MSGSTGNVENSVSGGQQARHDLFAGEAAALVRSRAGSSPG"
     gene            17526..17882
                     /locus_tag="KY5_RS25330"
                     /old_locus_tag="KY5_4983"
     CDS             17526..17882
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS25330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_4983"
                     /product="hypothetical protein"
                     /protein_id="WP_159072597.1"
                     /transl_table=11
                     /translation="MASLLGVVAMTGAAFAAGTATAGAVTPDAAPTSVASKSCGKGKTI
                     KAKESVKIRKTRKLNSTAKGLYPKGAKAKWAACEVKYGQTYSKCGWHNDNRWSYINYRG
                     TKGWIPTACENFIV"
     gene            complement(<18270..18451)
                     /locus_tag="KY5_RS42655"
                     /pseudo=""
     CDS             complement(<18270..18451)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015654825.1"
                     /locus_tag="KY5_RS42655"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVVGREVWSTSRRALAVRLTEAGVLSSPRWRAAVEAVPRELFLNP
                     GVFLPAEGAGGCRWP"
     misc_feature    complement(18422..18437)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.77"
                     /tool="antismash"
     gene            19010..19675
                     /locus_tag="KY5_RS25340"
                     /old_locus_tag="KY5_4985"
     CDS             19010..19675
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141212.1"
                     /locus_tag="KY5_RS25340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4985"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_098244376.1"
                     /transl_table=11
                     /translation="MLGDDAELTAAVLAAQDGDETAFRSVYRAVHPRLLGYVRTLVAEP
                     DAEDVASEAWLQIARDLERFSGDADRFRGWAARIARNRALDHIRMRGRRPAIGGDESEL
                     TGKPGEADTAGEAMESLATDAALALIAQLPQDQAEAVVLRVVVGLDAKSAAQTLGKRPG
                     AVRTAAHRGLKRLAELLGADGAGPTDALGAVPPQREPRGHAVTSAGVTHSRTRTQKDM"
     gene            19675..20895
                     /locus_tag="KY5_RS25345"
                     /old_locus_tag="KY5_4986"
     CDS             19675..20895
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS25345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_4986"
                     /product="hypothetical protein"
                     /protein_id="WP_098244377.1"
                     /transl_table=11
                     /translation="MADEQYQWLDRDAAERLLRGEPLEDVDPHVRAQAERIARALDALA
                     ADDRATVPGVDGSTGGTDGSTAGADRSAAALQAGAEPVAQSPAQQDAAQQQVQGELPGE
                     AAALAAFRAVGPGSARATTRSAAYATPAHEAAAGETVRLGRAAERPRPSRWGRPVRFGL
                     AAALAACMVGGVAVAAGTGVLPSPFGGHGESGPAASASPVATSEESLPTPSDDASEPSE
                     ELNPDASSAPDEEPTRETESSSPPEAEAGGDTTGTTKKPGGAETPRGDKTGDWYRKAVA
                     ACRAYRSGELQGEKRRRLEEAAKGRARVEEFCGRVLGGSGGGNGGGHGGANAGAGNGGN
                     GNGGDDGEDGGDDGEGGGSSGGGGEDGGDGGSSGGDTGGHPGPPQSSPSAPGTVPTASY
                     SALPNLP"
     gene            complement(21167..22066)
                     /locus_tag="KY5_RS25350"
                     /old_locus_tag="KY5_4987c"
     CDS             complement(21167..22066)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019981610.1"
                     /locus_tag="KY5_RS25350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4987c"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_098244378.1"
                     /transl_table=11
                     /translation="MGKGAISVGAVAVLVLAAGCKAAAIDTDGGRPSAAGGGGDGKPGA
                     SAPATPAPDPTPGRTKPSQPREPSQAPDPSKPREPQAPQEPQAPPKTLLARGAHGGQVR
                     ELQARLRQVAWFHENPTGTYGPATTAAVSGFQGKRGLPRTGAVDTATWQRLLAMTREPT
                     RFERYAGGGIPPAKPDPRCLTGRVLCIAKSSRTLTWMVNGKARSTMDVRFGAQYTPTRE
                     GTFSVYWKSRHHVSTLFHTAMPYAMFFSGGQAVHYSSDFAATGYGGASHGCVNVRDEKK
                     IAKLFGEVRKGDKVVVYK"
     misc_feature    22082..22100
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            22159..23739
                     /locus_tag="KY5_RS25355"
                     /old_locus_tag="KY5_4988"
     CDS             22159..23739
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118709.1"
                     /locus_tag="KY5_RS25355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_4988"
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="WP_098244379.1"
                     /transl_table=11
                     /translation="MTHESESGLPIEPVYGPEALAGWDPAERLGAPGAYPFTRGVYPSM
                     YTGRPWTMRQYAGFGTATESNARYRQLIEHGTTGLSVAFDLPTQMGHDSDAPIAHGEVG
                     KVGVAVDSVDDMRVLFDGIPLGEVSTSMTINAPAALLLLLYQLVAEEQGVDPARLTGTI
                     QNDVLKEYIARGTYIFPPGPSLRLTADVFRYCGAELPRWNTISISGYHMAEAGASPAQE
                     IAFTLADGIEYVRTAVAAGMDVDDFAPRLSFFFVARTTLLEEVAKFRAARRMWAEVMRE
                     EFGARNPKSLMLRFHTQTAGVQLTAQQPEVNLVRVAVQGLGAVLGGTQSLHTNSFDEAI
                     ALPTDKSARLALRTQQVLAYETDVTATVDPFAGSYVMERMTDDVEAAARELMLRVEDLG
                     GAVRAIEQGFQKGEIERNAYRIARETDSGERVVVGVNRFRSDEEEPYEPLRVDPAIEER
                     QSARLALLRAERDAAAVESALAALKEAAKGEANVLYPMKDALRARATVGEVCGALREVW
                     GAYEPTDAF"
     misc_feature    23903..23918
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.4"
                     /tool="antismash"
ORIGIN
        1 agggcgaaca gcgcggcgcc gacggacacg acgcgccggt cggatatctc gccgaccacc
       61 tctccttcga cctcgctttc cgggacgacc gtttcccccg tttcctcgat tccggccacc
      121 gtgccgaaat ccttccccgc ttcggccgcg atctccttct tcatttcccc accccatgcg
      181 cgtgaggggc cggtggcggc cgaccccgca aatcggcccg gttatacaac atccgggccg
      241 ccgttcacca ggcggggaag atagcggacg tagtgggtga ttatccgtca tgtcagctct
      301 aacagagctc acggcgtaag gcagttggtc ttgtgagaag cggcatgccg ggagcccgtc
      361 acagcagagc agtggcttcc gctgggtagg gggagggtgc gtcgcgcgct ctcccgatca
      421 ccgagtcgta ggagcggacg tcatggacga tgagggcaga caggtgccga gagccgcgga
      481 gatgcggggg cgggcccggg ggttcgtggc gcaggtgact tcgcggaatc ggctgccgct
      541 cgatttctcc gtcgccagcc tccgcgtggt cgacttcctc atcgaagggc tgcgcaaggg
      601 cggccgtgag cggagtgaga tcgcgggggc gttgttcggg ctcggggcct atgtcgggga
      661 agtcctcgtg cggcgtgcgg gtgccatgtg gatcgacctc gacaaggaac agcgggaatt
      721 cttcgggcag tccgtcggtg tccgaatgcc ggacggtcgg gtgtggaacc ccttggggaa
      781 ggtcgtcaat tgccttgagc gcggcggaat ggatggatcc gaatcctcgt tgcagatctt
      841 ctatctgacg ctgcccggac gggtcgggca cgcggcgtga attggccgtc gttggtttat
      901 tgagtcttct tttgttttgg gtgactgcgg cagagtgagc cgccgggcga ggcgcgcggc
      961 agggcacggg cacggtgggc ggtgtcggcg gggtgaagag gagagcgtgg ggcagggtgg
     1021 ggtacatcgc catgcggcgg gcagtgacga ggagttgacg cgggccctgg tggccgccgg
     1081 ggcgggggac gaggcggcct tcgccgtggt gtaccgctgt gttcatccgg gactcctccg
     1141 gtacctgcgc ggactcgtgc gcgaggacgc cgaggacgtc gcgtccgaga cctggctgca
     1201 gatcgtccgc gacctgcacc ggttccgcgg gggcggcggc gagttccgcc ggtggaccgc
     1261 gaccgtcgcg cgccaccggg cgatcgacca cctgcggcgg cagcgcagca ggccgcgccc
     1321 cgcgcacctt tcgcaggagg tgttcgacct gcccggcacg gacgacaccg cgggccaggt
     1381 cctcgaggca ctctccaccg cgcacgtgct gcgactggtg agcgcgctgc ccccggacca
     1441 gggcgaggcg gtgctgctgc gcgtcgtggt gggcctcgac gcccccgcgg ccgcccgcgt
     1501 cctgggcaag cggccgtcgg cggtgcggtc ggcggcgttc cgcggactcc ggcgcctggc
     1561 gggggagttg gacgccgagg cgccgacgcg gcggcgcgcc gccgggggcg agtacgcggt
     1621 gcgcagggtg agacgggcgg cctgctgaga gcggtttccg gccggatgtc acgagctcat
     1681 cgaaactctc cccaaagcct catgcgtctc gttagcctga cgagccatca ttcagcgatc
     1741 tggccactca cggccgcgga gaggcccgtg cctgaggaac tgggattcga tgagctgctg
     1801 gccgacggcg gcttgatcgc tcggctgctc ggcaggacgg cggccgggcg gaggcgggat
     1861 ctgctctacg gggacgacct gcccgtggtg ctgctcgtgg gcgggccggg gatggggaag
     1921 gggcggctcc tgcggtgtgt gcgggggcgg ttcgggccgc gcgtgcccac cgcgtacgtc
     1981 gactgcgccc tgacagggtg ccgggagcag gcggaggagc ggccgcggag ccggtcggaa
     2041 gtgaccgagg tgctcggcaa gatcgcctcg cagtacgtcg actggcgcgg tgacggcggc
     2101 gggatacccg tgccacggct ctacgcgggc ctcgcggccg tggcggcgag cgacccgctc
     2161 gcccccgcga cgcgcctggt ggacgaggtg ggccggctcg atggtctgct gccgcccggt
     2221 tccttctggc gcggcgtgct gaagggcacg gccaagaact acgtgggctt cctgctgggg
     2281 ctcgtcaccc atccgctggt cgggccgttc atcaacgcgc tcctcgacgg gctcctcgcc
     2341 cgcacctcca aggagggcag ggccgcgctg acggcttgct acggggacta ccccggcgcg
     2401 ggcggtcagc cgctggtcgg gctgcggtcg ctcgccgacg acttccagca gggcggggag
     2461 gcgcggcgga tcgccgaggg gttcctcctg cgggcactgc ggcaggacat cgacgccgcg
     2521 tacggcaacg tacgcggcca gttgacgcgc gtgggacggc ccgcgctgct cctcgaccac
     2581 gcggacggcg cgctgggcag gcgcctgctg aagcccgttc tcgaggaccg ggagcggggg
     2641 caccacgacc ggctcgtgat catcgcgacc gcccggcgcg aggacggtgg ccgcttcctg
     2701 cacagggcgg gcagcgacca cgacgacatg gccacgtggc ggcccttcat gggcgcgctg
     2761 cccgcgtgga gccgcccgcc ggacgccgtc cccgaccacg cgccgctgtg gcgcggcgtg
     2821 ctgcgcgtac ggatgcccgt gctcacccgc gaccagcaga aggacgagct cagcaggctc
     2881 aggggcggca gggagcagcc cgacaacgcc gtacgcctgc gcatccacag cggtgtgcac
     2941 cggctgagcg gcggccgccc gctgttcgtg acgcggctcg gcgaggcgac cgcggcggcg
     3001 tcgttcccca cgcccgagga gtgcaccgac tgggcgatcc tggacgcccg ggtgcccgcg
     3061 ggcgaggacg aacagggccg ccccgtcgcc gaccgcccgg tggccgacgt actcgtcgat
     3121 gaactcgtcg gccgcgaact ccccgaggag ctgccgcccg aacaccgagg ccactggctc
     3181 gacctgctca cccacctgtc ggtggcgcac gacgtggagt gcgcccagac cctggtgcgc
     3241 gccgtccagg aggaccgcag cgaacgcctc aacgcctacc gcatcgccga actcctggag
     3301 gacaccggct ggccccgctg cccccggcac ttcatcggcg acctcggcct gcgccgcctg
     3361 ctcacccggc gcctgtaccg gctgcgcgac ggcggcgcgg cctggcacgc ggaccacgcg
     3421 ctgctccagg gccactaccg ggacctcggc gaccaccacg ccgacgcgct gttcgtgacc
     3481 gcgggcgcgc accgcatgca ccacctcctc gcctccgacg gcgcggacct cgtcacgcgg
     3541 tacctggcgg ggaccttcct gacccggccc gccgccgagt ggtgcgagga actcctcgcc
     3601 gtcgcggacg ccgcgctgat cggcgcggac gacgaccgct acgcgcgcgc cctcggcgag
     3661 acgcaggtgc gcggcgacac cctgcgccgc agggtcgacc ggctgctgca cgcggtgtgg
     3721 ctcaccgagg accgcatcca gccgctggag gagaccgtgc cgacggtgct gcgcgggccg
     3781 ctgcgcgagc tcagcgagga gctgtcgaag atcgccgacg aggcggtgcg cgaccagggc
     3841 cccgagggcg cggacgtggc gagggcggcg gacggcgccg cgctgctcat ccgcatggcc
     3901 cgcgactggg gcgatcgcgc cgaggacaag cagccgctgc aacggtgcgt gtgcacggaa
     3961 cacatcgggt tcggctgacc cgcacggagg acgacggaga gggaggggca gcgttgaggc
     4021 agttcgggaa ctggctgtac aacacgttct gggccaactg gatgcgcagg atcctcacgc
     4081 tgctcggcct cgcggccgcg ggcgtgctcc tgtgggtgtt cctgccgccc atcggcgcac
     4141 ccgagagctg cgcctccggc gtcgagaagc acggcggcga gtgcataggc gtcaacggct
     4201 ccggctacga cttcggtacg ccggagatca gggaggtcgc gcgggcgatc gccaaggaga
     4261 acgagaagtt cgtcggcgac aagccccatg tcaccgtggc cctgatgctg ccgttgcagc
     4321 ccgacatcgc cgccgagcgc gtgcagttgc gcagcgagat ccagggggcc tatctcgcgc
     4381 agtaccggtc caatcgcaac gagagcaccc cgctgatgcg cctcgtgctc gccaatcccg
     4441 gtgacgggta cgcccaacag gccgcggtcg tcgaccagtt gggtgagatg tccagggaca
     4501 agagcgacaa cctccgcgcc gtcaccggct tcaacctgag cctggacgcc acggagaagg
     4561 ccatctcgcg cctgaccaac gaactgcaca tcccggtcct cgcgagccgg gtgagcgcgg
     4621 acgaactcgc caacccggag aagagcaccg gcaaggtccc ctatcccggc ctcgcccgca
     4681 tcatcccgac caaccgccag caggcggacg cgctggccag cttccacggc aggctcaagg
     4741 acgaggacac cgtcctggtc aaggacacgc ggccgcacga catctacaac gactcgctcg
     4801 ccaaggcctt cagtcgtacg gaaccgggcc ctccgggtcc caaggaccag ccgttcgaat
     4861 ccccctcgat caccgacccg ggggacacgg gcaacgactt caccctcatc gcccagaaca
     4921 tctgccagtc ctccgcgcgc tacgtctact tcgcgggccg ccccgtacac ctgcggctct
     4981 tcgccctgaa actggccgac gtgcagtgca agggcaagaa gtacacgatc gtcagcggct
     5041 cgggctcggc cacgctcaac cgctacatga agggcgacga ctgggcgaag ctgcgcggcg
     5101 gcgacagcaa ggagcccatc gtcacggtgc agtacgccgc cccggggcac cccgcggcct
     5161 gggacacgga gctcggccgc gagggcgcgg cgaagaagcg gcccgactac ttcaccgagc
     5221 cccagaagga gttgcgcgag ctgcgcctcc tgatcggcag gggatccgcg ggccacatcg
     5281 gcgacgtccg cctggacgac tcccgcacca tgctggtgca cgacggcgtc cgcaccatcg
     5341 ccaaggccgt cctgctcgcc aacgcccaga ccgagggcac ggtgccgccc ctgaagcggg
     5401 tctccgacat gtggcagcgg atcgaggcga ccaaccgggt cgtggggacc agcggcctga
     5461 tctgcctcac caacgcgggc aacgcctacg acaagccggt ggcggtggtc gaactgaacc
     5521 cgaccacgaa gaagttggag ttcgtgggca tcggatggcc caagggcaag ccgcagcccg
     5581 cggactgccg ggtgcccagc ggaacggggt gatccgccgg gcacccggcc tgccgcgtca
     5641 cggcgtcagc gcctgcccca gccgcgcccc ggcaggagtc ccaagatccg tacgcccgta
     5701 atagacgccg ctggaccccg gcacgcccga actgccgctg tccagctgga ggatcgtgcc
     5761 gtcgcccgcg tcctcgccct ccacgccgat ggccaggtcc gcgcgggcgg agccggagag
     5821 gtgcgccagg gtcgccgacg agccgaggcg gtcgccggtc tccgtggagc cggggacgcc
     5881 gggctcgtcc tgcgagaagg ccttcgcgcc cgtgccggtg aggccggacg aggagccctt
     5941 caggaggagg gaggtgcccg cgtcctcgcg ggcggtgccc gagcgggtga tgtcctcgcc
     6001 gggcgcgccg gtcaggacgt ccgcgtagcc gtcggcgttg tagtcgcccg ccgcgaccga
     6061 ccagcccatc gcgtcgcccg cctccgccgc gccggggacg ccggacgtgg cctggtggac
     6121 ggtcttcgcg ccggtcgacg tgaggcccgt cgacgtgccg ggcaccaccg tcacctggcc
     6181 gcccgcgtgc gcgcccgact cggcggtgta cggctggccg atgaccaggt cgtcgtagcc
     6241 gttgccgttg acgtcgccca cggcgaccga gcggccgccg ggcacggaca ggacgccgac
     6301 ccggctcagg cccgagcggc cgcccctgaa ccaggcgacc ttgcccttgc ccgcctggtc
     6361 gcggtaggtg agggcgacgt ccgcgtagcc gtcgcggttg aagtcgccgg acgccgcgtc
     6421 ggcgtacgcg atggccgtgt cgcccgaggt gaggctgccg cccgactcgt gttcggggtc
     6481 gagccgcgcg gcccacgagc cgcccgtgcc cgtcgcggtg gcgaacacgt ccgccttgcc
     6541 gtccgcgttg aagtcgccgg aggcgaccgc agagccgaac ctggcgccct tgtagtggaa
     6601 gtcgtccgcc agctgcatgt ccgtgccgga ggtgaacttc gggccgtaga gcatggtgac
     6661 cgcgccgcgg tcggtgttgc ccgccgcgtc gtcctcgccg ggcgcgccga tcacgaggtc
     6721 ggcgtagccg tcggcgttca ggtcgcccca cgcggtcgcc gcgccccagt cgtcgccggt
     6781 ctccgacgcg ccgggcacgc cctcactggc ctgcgtgagg gagatcttcg aggcggccac
     6841 gggcccttcg aggccgccgg gcacgaccgt gacgcggccg cggctcgacg acgccttggg
     6901 ggtgcccgcg atcaggtcgg tgatgccgtc gcggttgaag tccccggtgg gtatcgcgga
     6961 gttcttgccc gcgccgggct ccgccatcgc gtacggtacc gtgcccgcgc cccccagcac
     7021 gacggcgccg atcgtcagcc acgccctgcg ccgcagaccc agcggtctgt acgcatgcgt
     7081 ggaacgggct cttccgcggg tgcttccacg ggcttcctca cgtgctccgc gcggcctcaa
     7141 ttaccccacc cctcaacgaa ttccaggtga accaagcgag tccgtacgac cggccgaaga
     7201 gggaaagggt tgtaggagtg cgggcgattt gtcgcgtgac gtatcccgca cgccacaggt
     7261 gtgacagcgg ggcgggcggg tgcgctgggt catgtgagag gtgtgacgct gtgaaatgtc
     7321 tgtgggtggg gagtcacgtg tacgggcgta cggggacggg gacagggacg ggaagacggt
     7381 gggtgcgggc ggccgcgctc tcgctcgcgg tgggcgcggt ggcgggcgtc ctcacgtcct
     7441 gcggcaccca cgaccgcgcg gtgagctact ccgggggcac cctcgaaaag gtcacgcccg
     7501 agaacgagcg gcgcggcaag gaaatctccg tcgaggccat gggcctgttc aaggacgtgg
     7561 gatcgctgcg cctcgcagtc gacaggacca gcgcgcgggg ccgccagaag gtctccctgc
     7621 acatggaccg cgacagcaac tgcacgggca cgttcgacgc gggccccacg cagcgcggcg
     7681 acctcatcat gatcgagggc cgggcgacct acgtgcggtt cagcgaccgg tccctccagg
     7741 agatccgcga gctggcgatc cggcggggcc cggagatcgc cgcgcgggcc cgcgagcgga
     7801 cggcgctggc gcgcgggaag tacctgaaga tcccgacggg cggagccgtc ggctccgccg
     7861 cgatgccggt ggacagctgc gacctcgaca agatcaccag gcagatgccg ggcggccccg
     7921 gtccggacga cgtcatcaag gcccagggtc cgacccggcg ttacggcgag gacgtcattc
     7981 cgctcgtcga gcacggcaac ggggagacga ccgtgtacgt ggccgcgcac ggcaagccgt
     8041 acgtcctcgg cctggaggcg gcggagaacg gcgagacgat gaggatgcgg atgtccgact
     8101 acgacgagcc ggtcgaggcg gtggcccccg cggcggcgca gaccatcgac atctcggagg
     8161 tctcgggagg taccggcggc ggctcgctct tcgaggtgtg aggcgcgtac gccgggggac
     8221 ccgccgccag gaccgtgcgg cccgcgccga tggccgtgcc ctcccgcgct gtgacacttc
     8281 cgtgccgggg gacgctggtg accgtggggg gggcacgggc acggtgaacc gtgccgcgtc
     8341 ggccggatgg gaaagcgttg ggccagggtg ggagatcccg tcgcgcgcgg gcgcacgacg
     8401 aggaactggg cagagcgatc gcggcggcac agcagggcga cgaggccgcc ttcgccatcg
     8461 cctaccggct cgtccagccc gggctcgtcg gctatctgcg cggcctggtc ggcaccgagg
     8521 gggagaccgc ggaggacgtg gcggccgagg cctggctgga gatcgccagg gacctggggc
     8581 gcttccgcgg ggacggcgcc ggattccgcg gctggaccgc gacgatcgcc aggcaccggg
     8641 ccttcgacca cctgcgccga cagcggaccc ggccgcgccc cgcagccccg gaacaggacc
     8701 tgctcgaact gccgggcccg cacgacaccc ccgaacaggc cctcgaggcg atctcgaccc
     8761 gacgggtgct cgacctgatc ggcgaactgc cccgcgacca ggcggaggcc gtcctgctgc
     8821 gggtggtcgt cggcctcgac ggccccgcga cggcccgggt cctcggcaag cggcccggag
     8881 cggtacggac ggccgcccac cggggactgc gcaggctcgg ggagcgcctc ggccccgacg
     8941 gcgcggcgga tgaggggccc ggcacgctgg gcgagtcgag atgaagggcg cgcgccgggc
     9001 gcgggggtga tggcggagcg ggtggctcgg gccgtcgggc caggcgtaca gacgcggcga
     9061 ggccgagcct catcgaggcg cacacggagt cctctgctgg gcggtgtggt ccaggcggcg
     9121 gtgaagccgc cttcaggcgc ccggggcagg gggggcggtg gtggtgcgga aggagcgctt
     9181 ccgcacggga tatgccatgt ccatgttctg ttccgccccc ccctgcctcg ttggatgctt
     9241 tcgagccccc tgtgagcagg catgttgtgc aggggcaggg caaatgaata acgacgtgca
     9301 gcgtcacagc gtcactgatc tgccggcttc cttgtgctgt gtacctggtt tccggggtgc
     9361 acggtcgacg gtcggcagag ggcgcgtccg gtgggaggag cagagggatg gccacggtcg
     9421 tggcggacag cgtggtgccg gtggtgccgc tgctgaagcg ggtggtcggc ccgggggcgc
     9481 tgcgtgcgct gccggaggac cagttgccgg ggctggccgg ggagatccgc cggttcctcg
     9541 tcgcggaggg catcggcgac accaaccgcg tctccctctc ggccgacccc gtggaacagg
     9601 tcaaggcggg ctgccgcatc ccgcggaccc cgggactgcg ccctcgcaag ctggagatcg
     9661 ccgcctgccc cggccgcggc ggtcgcccgc gcctccaggc cgacatccac aaacctgttt
     9721 cccaggtcga ggcggccttc gacggcttcc cccaccccct gcgcgtctcc tacggcaacg
     9781 gacaggtctt ctgccacggc gaagtgctgc gcaccgcccc cgcatcagcg ttcgtcgaga
     9841 cgcaactggg cggagcgtcc cgcctgcccg acacgagtag cggcagcaca ccaagaagga
     9901 tggtcaactc cagtgaagcc ggtgaacaga catgaccgtc aacggatcac tgcctccctc
     9961 cctccagccc ttgccctcca tgctctcctg ccctgacccg ttggacccgg cccggatacg
    10021 tcatcaggtc gacgcggttc tgggcgcgtt catccaccac aagaaggccg cggctcgcga
    10081 acaggggctg cctgtcgagg ccccccaggc actggatgac tttctggcgg ccggcggtaa
    10141 acgcctgcgc ccgctgctgt gcgtgctggg ctggcacacc accggcagca gcagcggggg
    10201 cggcctggcg caggcggttc aggtgggcgc ggctctggag atgtttcacg ccttctgcct
    10261 catccacgac gacatcatgg accactccga cacccgccgc ggacggccta ccgtccaccg
    10321 cgcgctggct gcacgtcacc gtgcgggcca cgacgctgtt ctggccaagg acatcggcac
    10381 cagcgcggcc atcctggccg gcgacctcgc cctgctgtgg tccgacgaac tcctccgtgc
    10441 cccggacacc ggcctcggcc cggcccagct cgaacaggtg gcgccgctca tcgacctgat
    10501 gcggggggag gtgctgcacg gccagtacct ggacctgatc tccaccggac gcccctcccc
    10561 tgacaccggc ccggcgctgg cgatcatccg gtacaagacc gccaagtaca cctgcgagcg
    10621 gcccttgcac atcggtgccg ccctcgccgg agccgatgcc cgcttcctgg acgcactgag
    10681 cgcgttcgcg ctgccgctgg gtgaagcctt ccagctccgc gacgacctgc tgggggtctt
    10741 cggccatcaa gccgagaccg gcaagcccac cttcgatgac ctgcgcgagg gcaaacacac
    10801 cgtgctcatc tccttcgccc tgaaggccgc ggacgacacc caggcacggc tgctgcgcac
    10861 tctgtacggc aatgcccgcc tggacgagga cgacaccgac accgtgcggg ccgtcctgcg
    10921 ggccaccggc gcggaccagg ccgtcgagca catgatcact aaccgctacg agcaggccct
    10981 ggccgccctc gagggcctct ccctgccccg cgaggtgcac caccaactgc gcagcctcgc
    11041 agacaagacg gtgtggagga cgtcatgacc gcagccgttc gctcaggaaa cggagaccgg
    11101 cactcgggct acgacgcgac ctggttcgca gcagcccact ccaagaacct gaagcaccag
    11161 cagatcgtca acaccgtcgt ctgcgagaag aaggtgacct tgtaccggac cgctgacgga
    11221 gtcgtgcacg cgatcaaccc ggtctgcccg cacctcgggg cgagcctcgg gcacggtcgg
    11281 gtggagggag acaacatccg ttgtcccttc cacggcctgg cgttcaaccc cgaggggcga
    11341 tgcgtcgagg ttccctgggg ggctcccccc atccgtccga gcgtccagca ctaccgggtg
    11401 cacgagaaca acggattcat ctacgtctgg gtgagcgaga ccgaacctgc ctggacgccc
    11461 cttcacttgg accgatcccc gttcacctac gccgtcacct gggaagcgac gatcagtgcc
    11521 agcccccgcg acatggtcga gaacgctccc gattaccagc acttcgccgc cctgcacacc
    11581 atggaggcgc cccggcggac cgcccctacc gtctttgaga agcacgtgat gtcgatccgt
    11641 ctcaacgctg cgggattctg ggtgaactac cccacgctcg ccagcttgaa cgcggaggga
    11701 accggcctca tccacgccca cgtgacgatg ccccgtaccg ccttccggct cttggagatc
    11761 gtcacgcaga ccccggcaga ccaggggaca tcggttctgc gagtggcgac gtacgccaat
    11821 gccaccacct tcctcaaggg agcagcacgc aaaggggccg accgcctcgt cagccacctc
    11881 gcccactggg gggccaccca ccagatgaaa cgcgacatct tcatctgggc gcaccgggtc
    11941 taccccgagc acgcgcactt gaccaagggg gaggaggaca tcgccgcgct ccgacgatgg
    12001 atgaggcagt tcgacgaggc cgccccgcag ccggatcctc cgcccgccgc ctgaacgccg
    12061 ccacgggaca accggccccg gtgcctcgtc cgcacctgtt caggggcgac acgtgctcgc
    12121 ctgccatcgg ctaccacccg gagtcggccg tagagccgac tccccgacct gatgaggaag
    12181 agcggcatga cgatgcagcg ccacacatac ccctggggct ggtatccggt cgcgttcagt
    12241 cgcgacgttc cttcggggaa ggtcatcacc agcaagctcg ccgattcaga ggtcgtcgtc
    12301 tatcggaccg ctgacgggca ggcacatgtc atcttgccca cctgtccgca cctgggggca
    12361 cacctcggcg gtggtcacgt agagggccag ctcatcgtgt gccccttcca cgccttcggc
    12421 ttcgcccccg acggcacctg cgcacgaacg ggctacaaca ccaccccgcc ccacaacgcc
    12481 cgcgtgggta cgttccccac ccaggaagcc aacggcttcg tcttcgcctg gtaccacgag
    12541 gccgccacgg ccccggcctg gcgcatcgag caggtggacc tgaagggttt cggctacggg
    12601 taccgcaacc agaacacctt ccgcggaaac cagatcgatc tcctggagaa cggtgtggac
    12661 ctcgggcact tccaggtcgt gcacgcgaat caggcgaaga tcgtcaacgg tcatccgatc
    12721 gaagacgact ttcggtacgt catagacctc gaactcaccg gtttctaccg caacatcccc
    12781 acctacgtcc gcgcggagat gtacgggctc gggtacgcag tcgtgagtct gaagatgccg
    12841 aagttcgccg tgtccgcgta cgagatcatc ggatacacac cggagggcag cggcctcatc
    12901 acactgcgcc ggaccacggt cacccgctgc ggctccgcgc ccggaaatcc ggccggccgc
    12961 catatcctcc gggtcgtatc cacactggtg ggatacgtgg tgatgcggct gagcaccgtg
    13021 cagggaaaca acgacatcag gatctgggac cgccgcgtct tcatcgaacg cccgaagctg
    13081 gcccagggcg acgggcccat catgcctgcc cggaagtggg ccgagaagtt ccaccactag
    13141 ggctctcgga acgcaccgcc aaacccatcc actgttcagg aggacgcccg catgccaagg
    13201 accgaattcg acatccccgg gatctccgcg accagtcccc acgtccaggc cgcacgagag
    13261 cacctcctca agtggatgaa agggtacgac ctgcttccca gcgattcccg gactcagcag
    13321 ctaggaagtg aggacgtcgc cctcctgacg gccatgggct atccctgggc gggctcggag
    13381 gagctgaaca tcctgacgga ttacctcgcg gtgacatggg tgatcgacga cgggctcgac
    13441 acgaagttcg gccgcgagcc gcaccacgtg atcaagcttg tcgagcagct ctgtgccgtg
    13501 ctcgactttc acgccgtggg gcccgcgcca gtggtcgtcg atgccttcca cgatgtgtgg
    13561 aagcgcagtg tcgaggtcgc ctccccccac tggcaggaac acgcctctca cacctggcgc
    13621 gcctacttct ggggacaggc atgggaaacc atcaacaggt accgcgccat gaacgcgctg
    13681 gatctcgaga actacgtctc cctgtggaac atttgcagcg ggggcgccgt gtggttcgag
    13741 tacgtcgagc tgggtcacga agaattcccc cctgcctggt tccacagtcc agaagtccag
    13801 aacctgcgac gcgcggccaa cggcgtggca ctggcggtcg acgacctggc ttcgctggag
    13861 aaggaggaat ccgacgacga cgagcacaac ttcatcaaag tcatgatcaa cgcgcacggc
    13921 tacagccggg aagacgcgat cgcgaaagca gtcgcctggg gacaggagca ggccgacctg
    13981 atgcgccgct gttatgcgcg cctccaggcg tacgccgaac aacgcgtcgg cctggacgga
    14041 accgacatcg aaaagtgcct gcgcgccgca gacgcggtac tcgcgggcac acgcgggtac
    14101 cacgactggg cgctgatctc cccacgctac gggtcccacg gaatccaggt ccgcggcgat
    14161 ggaattgacg aaccgctccg agtgagggga ctgttctgaa ggcgagttgg acttccccgc
    14221 ggagcgacgc ttgtctcccc gtccgcgatt gatcggccca gccgcactct gcgggtcctg
    14281 accaggcgac tggcagcccg gcggcagggg accggaacag cggatgagct cgttcgggca
    14341 ccatttcagt ccgtgacctt gggctcgacg ccctgggggg ggcaaccgca acgtcgatca
    14401 gcccccctga caagggcaac acctccatca tgtggtcctg gctgctgccg cctacaccga
    14461 ggatgatccc gacgcggttg gcgccgcagg ccgagtgccc caggccgacg tcaccggcgg
    14521 ctttccgtcc ggcggcgagg gcgaggcgga tgaaccggtc ggtgcgcaag gccagacgcg
    14581 gcccggccgt agcggccagg gcggttcatc catgtggcag gggaagggag ccagcgagac
    14641 cgagtcctgc tcatccgtgc ccgtcgcctg ccagggcggt cggtcggcgc gagcctccgg
    14701 ccgccctggc agcgccgagt ccggggaagt gccccggcag ctctcctgga tcggctcagt
    14761 catgcgagcg atagcgtcgg catgacaccg gtgccgcacg gtcgagcgcg gccgcgagtt
    14821 cgcacggtgc gctacatcgg ccggttcctc ccggacgacc tgctggacgc gccgtgggca
    14881 cgtcatcgag cacttagccg tgcggctcgg catcggggat gtctcgtgcc tgaagcggta
    14941 caccgagcgc aagccgacgg catacggagc acgcgtggga gatccgggag tcctgcgagt
    15001 agcacgagga tgtggcgtgg tcgaggcggt cagcaccgtc ctgcacgggc gggcgtggac
    15061 tcaccgacag cgaactggca gaccatcaag gtaagcgctg gctcggcgga acgttgcaca
    15121 gctggtgctc cagttcccaa tcggccggtc ggcccttggg gtcgaaccat gcggatccgg
    15181 cattgagtca acggccgcga acgcggcggg cctgggccac agtgtcctct ccgatgctgg
    15241 actcggtacc gcagcactca cagacgacaa acagcgccaa gccgtgatcg tcgaagcaca
    15301 agagttcgtc aacttgacta ctgattgaca aagccaccgg gccctcgcgt cggtcgtgaa
    15361 ccgcacaaca tccagcgctt attcatcacg ctccgcgagg cgtgagccga gtcagcacct
    15421 tccggccgtt gtccgccatt ggagttttat cgcacccctg ttcgggtcac ttcaggtcag
    15481 tgagcactgg agcgtcatgc cccgggggaa cgcagttgag gtctcccggt gagggccggt
    15541 ccgctgcgcg acgtccctca accgtgtgcc cgtctctgca ccgccgaacc aaaaggagaa
    15601 actcgatgaa ccggcattcc tcccgctcca tgcggctggt gacgtccgcg atcctcacgg
    15661 ccccgctcct cgtcgtactc ccgggcgcag acctggcgca ggcgcaggcc ccagcgtgcg
    15721 gcggcacgcg cgacgcgtac gtgggcagca cctaccgggg caccaccaag accacgggat
    15781 cactgaaccc ctccctgctg ccgccgatcc tcaacccgca ccgcctcgac acgccctcca
    15841 ccccgctcag agcggctgcg ggcatcaacg ccgaggccga actggtggtc aagttcacca
    15901 aggacgcgcg gggcgaatac tgggcgaaca ccacggcgga cgggaaggtc acgagcagga
    15961 gcggctacac gctcaacctc accggggccc cgaaggtcga gttcaacgcc aagatgcacg
    16021 agcccgtgct ccacgaggtc tggcagacgg tgaagggcga gctcaagcac atcgacaaac
    16081 tggactccgt cggcaagtac atctacggct acgcgctcgc cgcccagaac tgcccctccg
    16141 gcagccagac ccccacggtc ctggcctcaa cggaggacaa cggcttcgga ctgcgcacga
    16201 ccacacgcct cacccgccag ggctgacacg agagggcctc acagtgatgt gcgcgctcct
    16261 cgaccacgcc gtcgacgaca gcgccgtgtg acactgccga aaacccctcc ccggcgaggg
    16321 ccgggccagg tcagagcatg tgaccccaca ccgaagagcc gggccgcaac catcgggcca
    16381 gagcctcgtt ctccgggcat gaagaagatc atctctgtcg ctggcctcgc tctcgccgtg
    16441 gcctgccttg ccgcccctgc ccacgccgac gacggcgaca acttcggtcc cggcatcaac
    16501 gccgcgaaca actggaactt caccgccgcc gccgtctgct tccaggaact cgccgtcgtg
    16561 cccgtgggcg gcgcctggaa cggcaacacg ctcaaccact gcgtgaacgg caacgtgctc
    16621 aaccacgcca agtagatccc ccgggctcag gcggcgaggc gaccggcctc gccgccggca
    16681 tcaaacgcag acccttgcag cctgcggcga gtggatgacg gtgggcgcgc tgctggatac
    16741 acgtccggcc tgcacccacc gtgacgctca tccacttccg cggccgctag ctgacctcgg
    16801 cttcggcagg ctacgtgacg ggcgggaagt ggagtgggcg aggcggatgg gtcgtcctgt
    16861 gttcacgcgc gaagtggatg gccgccgctg cagatccacc aagccgttca aggaagaacg
    16921 cgcgtgccat ggaccgtctt tgctcatcgt tcacgtgcat gatccaccgg gccggtgcgg
    16981 ggacgaagtg ggcggctgcg acggcttccg tcaggccggg tgccgggccc cggcgcagtt
    17041 gtccggtcag cgcggtgtac cgacgcaggg cgtccatctc cgagcggcgc agcccaaccc
    17101 ttctccggcc tggctcggct gcctgggcgg gcgctgggga gagtggccca cgaggagcag
    17161 cacgccgatt cggacccacc ggcctacccg ggggaactac ctgcccggga gcgcaccaac
    17221 gcggccgctt ctcccgcgaa gaggtcgtga cgcgcctgct gtccgcccga gacggagttc
    17281 tccacattgc cggtgctgcc gctcatttgg tcttccgctc cgacaggatc gctcaacggc
    17341 gggtccggcg ggtccggcgg gagccttcgg gaggtcggcg ccgcgtctcc tttcacgtct
    17401 ccttccgtgt ttctctccat atcctttccg ttcgcgtacg cgatcatgat gacctagggt
    17461 gtgcggcgta ccgcggggtg cgcagaagcc ccgcagctag cgaacggggt tgtgcagtgc
    17521 ggaagttggc ttctctgctg ggtgtcgtgg cgatgacggg ggccgcgttt gcggccggaa
    17581 cggcgacggc cggtgcggtc acgccggatg ccgctcccac gagcgtggcg agcaagtcgt
    17641 gcggcaaggg gaaaacgatc aaggcgaagg agagcgtcaa gatccgcaag acgcggaagc
    17701 tcaactcgac ggccaagggc ctgtacccga agggtgccaa ggccaagtgg gccgcgtgcg
    17761 aggtgaagta cgggcagacc tactcgaagt gcggctggca caacgacaac cggtggtcgt
    17821 acatcaacta ccgggggacc aagggctgga ttccgaccgc ctgcgagaac ttcatcgtct
    17881 gagctgacgc acgcatgagg ggcccggaac cgccgtcacg gttccgggcc cctcatattc
    17941 gcgtcgcctt ccagccgagc ccgttccagg tccgacagat cgcccctccc cacgcctggc
    18001 agaacgagtg aacgcgaaca ccgtcacccg acccgtcgga caggctctag ctgactcgcc
    18061 ccgcagcccg gatgcgatgg gccgaactgc cgggcggtta gaagaagagg agcctcggat
    18121 actgaggcgg ccccccaagc cagtgtcttg gtcctgtact gcgtggcggg tcggctgaaa
    18181 ctgcagtagt tggtcgtgtc gtccacgtat acgcggagta ccggcagttg catgcgtctc
    18241 tgtacccact gggccgggtc ggtgccgacc gcggccaccg gcagccaccg gccccctccg
    18301 cgggcaggaa cacgccgggg ttcaggaaca gctcgcgggg aacggcctcc accgccgccc
    18361 gccagcgggg gctggagagg acgcccgcct ccgtcaggcg gacggcgagg gcgcgccgcg
    18421 aagtgctcca gacctcgcgg ccgacgacca gcacgcgcag atctgctgcc ttgtcgacca
    18481 cggcctggat gtggaaggaa gagctcggct cgaactggga cgatcacggc ctggtcttcg
    18541 cacgtgacgg ctacaggctg tgtaagggcg ggacagcccc gggcggcccg caagatgccg
    18601 gccaggtcag cgcccgatgg tgctccacca gggagcggct cggtcttccg ggaggccggc
    18661 actgcccagc gcatcggcct agagggcatg gggtgagtct gaagatgcgt tggccacgct
    18721 gtgggccatg tagatgcccc gcactccgag tcttggcaga ccggagcacg gggcatctcc
    18781 gcgacgaccg gggccgccac cccccacagg agaggccccg gccggcacgc ggcacgaacc
    18841 gcgtgcggtc cgtacttcct tcagcgccgc gcgtgcgttt tctgtcacac cgcgctctgt
    18901 cactcggtag ttgcacgttg tacaaacatg gacgtgggcc tggcgaggcc gtagcgtgct
    18961 gcttcgcgcc ggggccgggc gcagatctcc gagtggcagg attgagagag tgctggggga
    19021 cgacgcggag ctgaccgccg cggtgcttgc ggcgcaggac ggggacgaga ccgcgttccg
    19081 ttctgtgtac cgcgctgtgc acccgcggct gttgggatac gtacgcacgc tggtcgccga
    19141 gccggacgcc gaggacgtcg cctccgaggc ctggctgcag atagcgcgcg atctggagcg
    19201 cttcagcggg gacgccgacc ggttcagggg ctgggcggcg cgcatagcgc gcaaccgcgc
    19261 cctcgatcac atacgcatgc ggggccgccg ccccgcgata ggcggcgacg agtccgagct
    19321 gactggcaaa cccggcgaag cggacaccgc gggggaggcg atggagtccc tcgccaccga
    19381 cgcggcgctc gccctgatag cgcagctccc gcaggaccag gcggaggccg tcgtgctccg
    19441 cgtcgtcgtc ggtctcgacg cgaagagcgc ggcccagacc ctcggcaagc gcccgggggc
    19501 cgtccgtacg gcggcgcacc gcgggctgaa gcgactcgcg gaactgctcg gcgcggacgg
    19561 cgcgggaccg acggacgcgc tgggcgccgt accccctcag agagaaccgc gtgggcacgc
    19621 ggtgacgtcc gccggtgtga cgcattcgcg tacgcggacg cagaaggaca tgtgatggcc
    19681 gacgagcagt accagtggct ggaccgggac gcggcggagc gcctgctgcg cggggagccc
    19741 ctcgaagacg tcgaccctca cgtgcgcgcg caggccgaaa ggatcgcccg cgcgctcgac
    19801 gcgctggccg ccgacgatcg cgcgaccgtc cccggagtgg acggttccac cggtggcacg
    19861 gacggttcca ccgcgggcgc ggaccgttcc gccgcggcgc tccaggccgg tgcggagccc
    19921 gtggcgcaga gccccgcgca gcaggacgcg gcgcagcagc aagtccaggg tgaactcccg
    19981 ggcgaggccg ccgcgttggc cgccttccgg gcggtgggtc ctggttccgc gcgggccacc
    20041 acccgctccg ccgcctacgc gacgcccgcc cacgaggccg ccgcgggcga gaccgtgcgc
    20101 ctcggccgcg cggccgagcg cccgcgtcct tcccggtggg gcagaccggt gcggttcggg
    20161 ctcgccgccg cgctcgcggc gtgcatggtc ggcggtgtcg ccgtggcggc gggcacggga
    20221 gtgctgccct cgccgttcgg cggtcacggc gaatcgggcc cggccgcttc cgcatcgccc
    20281 gtcgccacct ccgaggagtc cctgccgacg ccgtcggacg acgcgagcga gccctccgag
    20341 gagctgaacc cggacgcgag cagcgcgccg gacgaggagc ccacgcggga gaccgagagc
    20401 agctcgcccc ccgaggccga ggcgggcggc gacaccacgg gcaccacgaa gaagccgggc
    20461 ggcgccgaga cgccgcgggg cgacaagacc ggggactggt accgcaaggc cgtggccgcc
    20521 tgccgcgcct accgcagtgg cgagctccag ggcgagaagc gccgccgtct cgaagaggcc
    20581 gccaagggac gcgcccgcgt ggaggagttc tgcggccggg tgctcggcgg ctcgggcggc
    20641 ggcaacggcg gcggccacgg cggcgccaac gcgggcgcgg gcaacggcgg caacggcaac
    20701 ggcggtgacg acggcgagga cggcggcgac gacggcgaag gcggcggttc gagcggcggc
    20761 gggggcgagg acggcggcga cggcggctcc tcgggcggcg acaccggggg ccaccccggc
    20821 ccgccccagt cgtccccttc cgcccccggc acggtcccca cggcgtccta cagcgctctg
    20881 ccgaacctgc cgtaacccct gcgtggcggg attcagagac cgggtgtgac gtttttcggc
    20941 acggtggcgc agtaagtagt gagccgactg gtcatcggcc cgcgcacgag ccgggggttc
    21001 cccccgtacc ttcggctccg tgccaccagc gtgggcggga tacgttcccc cgatcccgcc
    21061 cacgctgctt tctctccccg gacgacccgc tctctgcggg acgccttcac ttgtagacga
    21121 cggccgtcac ttgtagacga cggccgtcac ttgtagacgg cggccgtcac ttgtagacga
    21181 cgaccttgtc gcccttgcgc acctcgccga agagcttcgc gatcttcttc tcgtcccgga
    21241 cgttcacgca gccgtgcgag gcgccgccgt agccggtcgc cgcgaagtcc gacgagtagt
    21301 gcacggcctg gccgccgctg aagaacatcg cgtacggcat ggcggtgtgg aagagcgtcg
    21361 agacgtggtg ccgcgacttc cagtagacgc tgaaggtgcc ctcgcgggtc ggcgtgtact
    21421 gcgcgccgaa gcgcacgtcc atcgtcgagc gggccttgcc gttcaccatc caggtcagcg
    21481 tgcggctgct cttggcgatg cacaggacgc ggcccgtcag acagcgcgga tcgggcttcg
    21541 cgggcgggat gccgccgccc gcgtaccgct cgaaccgcgt cggctcgcgc gtcatggcga
    21601 gcagccgctg ccaggtggcg gtgtccacgg cgccggtgcg gggcaggccg cgcttgccct
    21661 ggaaaccgct gacggcggcg gtggtcgccg ggccgtacgt cccggtcggg ttctcgtgga
    21721 accaggcgac ctggcgcagc ctggcctgca actcccgcac ctgcccgccg tgcgcgcccc
    21781 gggcgaggag cgtcttcggc ggcgcctgcg gttcctgagg cgcctgcggt tcccgtggct
    21841 tggacgggtc cggcgcctgc gacggctccc tcggctgcga cggcttcgta cgaccgggtg
    21901 tcgggtccgg agcgggcgtg gcgggcgccg aagcgcccgg cttgccgtcc ccgccgcctc
    21961 ccgccgcgct cggccgcccg ccgtccgtgt ctatcgccgc ggccttgcac cccgcggcga
    22021 gcaccagcac cgccacggct cccaccgata tcgcgccctt gcccatcacg ccccccagtg
    22081 ctcctggaca tcactccagg aagtgtttcc cggtttgccg cgagtgacgc gtgcccgtcg
    22141 cgggcgcaag ctggaggcat gacacacgag tcggagtccg gactgcccat cgagcccgtg
    22201 tacggacccg aggcgctggc cggctgggac ccggccgagc ggctcggcgc gcccggcgcg
    22261 taccccttca ccaggggcgt ctacccctcc atgtacaccg gccgcccctg gacgatgcgc
    22321 cagtacgcgg gcttcggtac ggcgacggag tccaacgccc gctaccggca gctgatcgag
    22381 cacggcacga cgggtctgtc cgtcgccttc gacctgccga cccagatggg ccacgactcc
    22441 gacgccccga tcgcgcacgg cgaggtcggc aaggtgggcg tggccgtcga ctcggtggac
    22501 gacatgcggg tcctgttcga cggcatcccg ctgggcgagg tctccacgtc gatgacgatc
    22561 aacgcgcccg ccgcgctgct cctgctcctg taccaactgg tcgcggaaga acagggagtc
    22621 gaccccgcac ggctgacggg cacgatccag aacgacgtgc tcaaggagta catcgcgcgc
    22681 ggcacgtaca tcttcccgcc cggcccctcg ctgcgcctga ccgcggacgt cttccggtac
    22741 tgcggcgccg agctgcccag gtggaacacc atctcgatct ccggctacca catggcggag
    22801 gcgggcgcat cgcccgcgca ggagatcgcc ttcaccctcg ccgacggcat cgagtacgtc
    22861 cgtacggcgg tcgccgcggg catggacgtg gacgacttcg cgccgcgcct gtccttcttc
    22921 ttcgtggccc gtacgacgct cctggaggag gtcgccaagt tccgcgcggc ccggcgcatg
    22981 tgggccgagg tgatgcgcga ggagttcggc gcgcggaacc ccaagtcgct gatgctgcgc
    23041 ttccacacgc agaccgcggg cgtccagctc accgcgcagc agcccgaggt gaacctggtc
    23101 agggtcgccg tccagggtct cggcgcggtc ctcggcggca cccagtcgct gcacaccaac
    23161 tccttcgacg aggccatcgc gctgcccacc gacaagtccg cgcgcctggc cctgcgcacg
    23221 cagcaggtcc tcgcgtacga gacggacgtg accgccacgg tggacccgtt cgccgggtcg
    23281 tacgtgatgg agaggatgac ggacgacgtg gaggcggccg cgcgcgaact gatgctgcgc
    23341 gtagaggact tgggcggcgc ggtgcgcgcc atcgagcagg gcttccagaa gggcgagatc
    23401 gagcgcaacg cctaccggat cgcccgcgag accgactccg gcgagcgcgt cgtggtcggc
    23461 gtcaaccggt tcaggtccga cgaggaagag ccctacgagc cgctccgcgt cgacccggcc
    23521 atcgaggagc ggcagagcgc ccgcctcgcc ctgctgcgcg cggaacgcga cgcggcggcg
    23581 gtggagagcg ccctggccgc gctcaaggag gcggcgaagg gcgaggcgaa cgtcctctat
    23641 ccgatgaagg acgcgctgcg ggcgcgggcg acggtggggg aggtctgcgg ggcgctgcgg
    23701 gaggtgtggg gagcgtacga gcccacggac gcgttctgag gggccgcggg tcgcggggcc
    23761 gcgggcttca cgctcctcgg gctgcgcgtc gcgcggtcgc ttcgtagagc gcatgctccg
    23821 cactccgggc gttccgcgcg cacgggcgcg cacagtcatg aggggcgcgc gctgtccggt
    23881 ctccggacac ccgtgcccta tgtcgtacgc gcgtgcgaca ctccggccat gctgggtgtc
    23941 acagaccttc ctacgtatct cgcgggcctc gtcctgatcg tcctgcttcc ggggccgaac
    24001 tcgctgtacg tgctctccgt cgccgcgcgc cggggcatac gcaccgggta caccgcggcc
    24061 gcgggcgtct ggtgcggcga caccgtgctc atgacgctgt ccgcggccgg tgtggcctcg
    24121 ctgctccagg ccaacgcggt gctcttcggg atcgtgaagt acgcgggcgc cgggtacctg
    24181 acctggctcg cgatcggga
//
