LOCUS       NZ_CP022685            22733 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2833548
            Orig. end                         :: 2856281
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22733
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="19"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22733
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22733
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12733](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12733)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(319..864)
                     /locus_tag="KY5_RS11965"
                     /old_locus_tag="KY5_2379c"
     CDS             complement(319..864)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103416.1"
                     /locus_tag="KY5_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2379c"
                     /product="hypothetical protein"
                     /protein_id="WP_098242224.1"
                     /transl_table=11
                     /translation="MLSPVSVRRAGVSLTLCCTLLVGATACNDDDKDSAATPTGSSSAE
                     KQKFAKTRFVANAGLAAGATYQWIVKPFRAGKFKSGADGRRFALIKAGLAGAFTYNRLK
                     AATKNAQGDPTLAKAVAPLSAGIDALKDLPSKLRKGEGTDSIVNSFDGIINDVKGAGSS
                     AGAEVKDKVPSAGELAKG"
     gene            993..1292
                     /locus_tag="KY5_RS11970"
                     /old_locus_tag="KY5_2380"
     CDS             993..1292
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010048443.1"
                     /locus_tag="KY5_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2380"
                     /product="hypothetical protein"
                     /protein_id="WP_098242225.1"
                     /transl_table=11
                     /translation="MSPRTRNTRGTNEAARVIAIVADVMAFILGLWILMYLLDANRAND
                     LVQFVHDVARWLAGWSHDLFTFDAAWARVVAGYGLAAIVYLFIGHAIAGRLRRY"
     gene            complement(1452..2522)
                     /locus_tag="KY5_RS11975"
                     /old_locus_tag="KY5_2381c"
     CDS             complement(1452..2522)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060427.1"
                     /locus_tag="KY5_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2381c"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_098242226.1"
                     /transl_table=11
                     /translation="MTSPERTEHLVLPGVLTADQAAATVRGILAVQREDGAIPWFRGHH
                     LDPWDHTEAAMALDAAGEHAAAERAYDWLARHQNPDGSWYAAYRDGDPHDITDRGRETN
                     FCAYLAVGVWHHYLATGDESFLDRMWPAVVGAVEFVLALQQPGGQIGWKREPDGTPVTD
                     ALLTGSSSIHQALRCALAIAEQRDEAQPDWELATGALAHAIRHHPERFLDKDRYSMDWY
                     YPVLGGALTGAAAKSRIEEGWDRFVVPGLGVRCVVPNAWVTGGESAELALALWALGESD
                     RALDILQSIQHLRDPATGLYWTGFVYDDEAVWPEELTTWTAGSLLLAVAALGGDEATCA
                     VFSGERLPGGLDPDCC"
     gene            complement(2519..3271)
                     /locus_tag="KY5_RS11980"
                     /old_locus_tag="KY5_2382c"
     CDS             complement(2519..3271)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103413.1"
                     /locus_tag="KY5_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2382c"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_055544696.1"
                     /transl_table=11
                     /translation="MLTVDFTRFPLAAGDRVLDLGCGAGRHAFECYRRGAQVVALDQNA
                     EEIREVAKWFAAMKEAGEAPAGATATAMEGDALNLPFPDASFDVVIISEVMEHIPDDKG
                     VLAEMVRVLKPGGRIAVTVPRYGPEKVCWTLSDAYHEVEGGHIRIYKADELLGKMRESG
                     LKPYGTHHAHALHSPYWWLKCAFGVDNDKALPVRAYHKLLVWDIMKKPLATRVAEQLLN
                     PVVGKSFVAYATKPHLPVAAAESVADAK"
     gene            complement(3265..4683)
                     /locus_tag="KY5_RS11985"
                     /old_locus_tag="KY5_2383c"
     CDS             complement(3265..4683)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672414.1"
                     /locus_tag="KY5_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2383c"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_098242227.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 9.3e-29,
                     bitscore: 99.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEAMEAGPRKGSAAEGDRPLRIALLTYKGNPFCGGQGVYVRHL
                     SRELVRLGHTVEVIGAQPYPVLDEGEGLEGLSLTELPSLDLYRSPDPFRTPGRDEYRDW
                     VDALEVATMWTGGFPEPATFSLRARRHLRARRGEFDVVHDNQTLGYGLLGDLGAPLVTT
                     IHHPITVDRRLELDAAPDLKRRMSVRRWYAFTRMQKRVARRLPSVLTVSGTSRQEIIDH
                     LGVRDDRIDVVHIGADTDLFSPDPSVAEVPGRIVTTSSADVPLKGLIHLVEALAKVRTE
                     NPAAHLVVVGKRAEDGPVAQAIERHGLAGSIEFVKGITDAELVDLVRSAQIACVPSLYE
                     GFSLPAAEAMATGTPLLATTGGAIPEVAGPDGETCVAVPPGDPEALALGLNRLLGDAGL
                     RARLGAAGRARVLDRFTWARAAQGTAELYRAAIDRSAGRGATRAVARGHALPAATAAAA
                     PEVAGPHHESRATC"
     misc_feature    complement(4728..4744)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.82"
                     /tool="antismash"
     misc_feature    4737..4750
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     gene            4896..5516
                     /locus_tag="KY5_RS11990"
                     /old_locus_tag="KY5_2384"
     CDS             4896..5516
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641457.1"
                     /locus_tag="KY5_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2384"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_098242228.1"
                     /transl_table=11
                     /translation="MTAEAKTGSPATPPLTERQEARRRRILHASAQLASRGGFDAVQMR
                     EVAEAAGVALGTLYRYFPSKVHLLVATMQDQLQHMHTTIRKRPPAGETPAERVAETLMR
                     AFRALQREPHLADAMVRALTFADRSVSPEVDTVSRLTTAIILDAMGLAEPPTAQQLSAV
                     RVIEHTWHSALITWLSGRASIAQVKIDIETVCRLIDLTATPRA"
     gene            5660..6268
                     /locus_tag="KY5_RS41750"
                     /old_locus_tag="KY5_2385"
     CDS             5660..6268
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655807.1"
                     /locus_tag="KY5_RS41750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2385"
                     /product="response regulator transcription factor"
                     /protein_id="WP_159072517.1"
                     /transl_table=11
                     /translation="MIRVLLVHDACLLRLALAERLAREPDLEVFHAPWSQAHGRQRTVR
                     PDLCVVDLDDESTYALTPLTELTGPSAHGRGCRVLVLATANRPGQLRRAAEADALGYVN
                     KASQPERLITGIRQVAAGQRFVDDSLGFGFLKAAQMPLTQRELSVLSLAARGASVAEIA
                     HSLHLSNGTVRNYMAAITRKTGARNRIDAIRISQGEGWV"
     misc_feature    5702..5704
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<6530..7591)
                     /locus_tag="KY5_RS43050"
                     /pseudo=""
     CDS             complement(<6530..7591)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="KY5_RS43050"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSRSFVFTAVGALVGLFSLDPLLLLVVAPPLLAGIALFVATLRP
                     LARRQEEFLVADEELAARLGVVCPGLRDVTAAGAEDDVAADLGRGVAREYRTAAALARW
                     GVLRTASLAIGGQLPLILLLTTAPWLLDNGVTPGALVGALAYVTQALLPALHNLVHGLG
                     ASGSRLAIVLRRLMWEGPGSGGGAEAGRAGQGPALELSSVTFAYGPHAEPVLRNLGLSV
                     ARGEHLAVVGPSGIGKSTLAGIVAGLLVPDAGEVRVEGAGVRGEGAVGRRVLIPQEAYV
                     FTGTLRENLEYLRAEPVPESELTGAAEAVGLAPLVARLGGLDTELVPGELSAGERQLIA
                     LTRAYVAYAPLAIL"
     gene            complement(7984..9711)
                     /locus_tag="KY5_RS12000"
                     /old_locus_tag="KY5_2387c"
     CDS             complement(7984..9711)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003837.1"
                     /locus_tag="KY5_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2387c"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098242229.1"
                     /transl_table=11
                     /translation="MATTTPRPHQPTHDAHLLGAAARHSALRCVILALCALASAGAGLL
                     LPLAIGRALDAVLTGHLTGAADADATRWIAACAALITASAVLDALDGVLTGTTNARTTA
                     WLRGRVTGHVLAVGPRTTARFAHGDLVARLIDNAAHAGIAPATFAALLAALVTPVGAVV
                     ALALIDGWLAAVFLVGAPVLFLLLRTFVRVSSDCVARYQRVQGNIAGRLSEAIGGARTV
                     AAAHTQDKEAARVLGELPELGRQGRRMWRLQGRSQAQAVAVAPLLQIAVAAVAGLLLLR
                     HRISVGDLLAASRYAVLATGIGMLVGQLGGLVRARAAARRLEEVLTEPPTSYGEAELPP
                     EGGLLELRGVMASRGGRTVLDGVDLTVPAGTTLAVVGRSGAGKSLLAALAGRLADPDEG
                     EVRLDGVPLRSLGRQELRREVGYAFERPALLGTTLEDTIGLGAPRPTPGRIREAARAAR
                     ADTFITRLPDGYATPCGQAPLSGGESQRLGLARAFARGGRLLILDDAMSSLDTVTEHHI
                     ADALLHHTPHRSRLIIAHRAATAARADAVAWLHEGRIRAVGTHEELWERPEYREVFGA"
     gene            complement(9828..9953)
                     /locus_tag="KY5_RS12005"
                     /old_locus_tag="KY5_2388c"
     CDS             complement(9828..9953)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="KY5_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2388c"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_098242230.1"
                     /transl_table=11
                     /translation="MALLDLQSMESDELTGGGHGGGGSVASLLLCWSDASIVLCL"
     CDS_motif       complement(9894..9953)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQSMESDELTGGGHG"
                     /locus_tag="KY5_RS12005_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9828..9893)
                     /prepeptide="core"
                     /locus_tag="KY5_RS12005_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="15.20"
                     /molecular_weight="1992.3"
                     /monoisotopic_mass="1991.0"
                     /core_sequence="GGGSVASLLLCWSDASIVLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQSMESDELTGGGHG"
                     /leader_location="[9893:9953](-)"
                     /alternative_weights="2010.4"
                     /alternative_weights="2028.4"
     gene            complement(10001..12733)
                     /gene="lanKC"
                     /locus_tag="KY5_RS12010"
                     /old_locus_tag="KY5_2389c"
     CDS             complement(10001..12733)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983511.1"
                     /locus_tag="KY5_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2389c"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_098242231.1"
                     /sec_met_domain="micKC (E-value: 2e-232, bitscore: 772.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.3e-09, bitscore: 34.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.2e-07, bitscore:
                     28.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYCLADRFFYETPDRLSSTGTRSGARAFPVSQRPVPEGW
                     RSARAGDWFSLVPIGDDGAPLPTPQQGWKIHVSATLENADRIAALVWDHCVPRSVPFKF
                     VPAKHLLHLRNSKYAGRDMSGKFATVYPADENQLHELLDELGKLLEGFEGPYILTDLRW
                     EQGPLYVRYGAFTRRMCDDGKGTLVPAVEDGEGKLVPDDRGPAFKVPAWVKLPDFLEPA
                     LAARNTTTVGDLPYRIEKALHFSNGGGVYAGTDTRDGSKVVLKEGRPHAGLASDGADAV
                     ARLERERDALQKLSGLGVAPEVRDWFLLGEHRFLVMDFLEGSTLNSFFAHRHPLCTSEP
                     DAADISEYTAWALRMHRAVEEAVTAVHERGVVFNDLHLFNIMVAPDEQSVSLLDFEAAA
                     AVGDEGRQIVAHPGFLAPPDRTGVDVDRYALACLRLALFLPITTLLSIDRGKAAHFAQV
                     IATEFPDVPAEFLAEAVAEIERGAPGGDGGTPGANGDERAPVRGAGDTEALESGLPKGG
                     ATGAAGPAARVAAPLVDPADWPYSRDSMVKAILASATPERDDRLFPGDIAQFADGGGLG
                     LAHGAAGVLLALAESGAERYEEGERWLLDHSRPAPAGTPLGLHDGLAGIAHVLDRLGHR
                     ERALDLTELILQERWQRLPSDLYGGLAGVGLALDSLAESTGERTLGQYALRAAELLGER
                     LASEEPPKNGRRRAGLLRGATGPALLFLRLYERGGDPALLDLAARALRADLDQCVTQKR
                     DGSLAVNEGWRTMPYLGDGSVGIGMVIDDYLAHRDDERFEAARPGILAAASSRFCVQPG
                     LFQGRAGLLLHVNRSTTPGITPEDVAAQIEELGWFAMSYAGQLAFPGNQMLRLSMDLNT
                     GTAGCLLALASALGDTGAHVPFLPPIRRPQSRSRDTAGS"
     misc_feature    12865..12879
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.92"
                     /tool="antismash"
     gene            complement(12975..13208)
                     /locus_tag="KY5_RS12015"
                     /old_locus_tag="KY5_2390c"
     CDS             complement(12975..13208)
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989875.1"
                     /locus_tag="KY5_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2390c"
                     /product="ferredoxin"
                     /protein_id="WP_098242232.1"
                     /transl_table=11
                     /translation="MGDRWHVEVDRSVCIGSGMCVGTAPDGFTLDTARQSHPTHPDTDA
                     NEKVLEAAEGCPVEAITITLADSGEVVFPPED"
     gene            complement(13208..14674)
                     /locus_tag="KY5_RS12020"
                     /old_locus_tag="KY5_2391c"
     CDS             complement(13208..14674)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381665.1"
                     /locus_tag="KY5_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2391c"
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_098242233.1"
                     /sec_met_domain="Aldedh (E-value: 1.8e-149, bitscore:
                     497.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELVEHGQLFIGGELVDPLGKGVIDVVSPHTGKVFARVPHAAPA
                     DVDRAVATARKAFDDGPWRRMTLDERIEVVTKIKDGIAVRHEEIARAISSENGTPYTSS
                     VMVQALAAMMAWDAAITVARDFTYEEARDGVLGKLLVRREPVGVVAAVVPWNVPQFTAA
                     AKLAPALLAGCPVILKTSPEAPLDAYILAEIAAEAGLPQGVLSVISADREVSEYLVAHP
                     GVDKVSFTGSVAAGKRVMEVAARNLTRVTLELGGKSAAVILPDADAATAVAGITPFAWM
                     INGQACVAQTRILVPRTRYDEFAEAFAAAASALKVGDPLDPATELGPLVAKRQQQRSLD
                     YIRIGQEEGAKILAGGGRPAGLDQGWYVEPTLLGGVDNSMRVAREEIFGPVICLLPYGE
                     QDEAVKIANDSDYGLSGSVWTADVERGIDVARQVRTGTYSVNTFSLDMLGPFGGFKNSG
                     LGREFGPEGYAEYFEHQMIHLPAGYEGSGA"
     misc_feature    complement(14734..14747)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.52"
                     /tool="antismash"
     misc_feature    complement(14811..14824)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.68"
                     /tool="antismash"
     misc_feature    complement(14817..14830)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.91"
                     /tool="antismash"
     gene            14865..15920
                     /locus_tag="KY5_RS12025"
                     /old_locus_tag="KY5_2392"
     CDS             14865..15920
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989877.1"
                     /locus_tag="KY5_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2392"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_098242234.1"
                     /transl_table=11
                     /translation="MTPQVTDPPVIEHGGGVWSIKVPIPDNPLGFTLVHLLDTDRGAVL
                     VDTGWDDPASWHTLADGLAACGVAVADVHGVVITHHHPDHHGLSAKVREASGAWIAMHE
                     ADASVVRRTRSNPPERWYAYMAAKLTAAGAPEEHVAPLVRAAEEGRPRRLPGLDPALPD
                     RDIVPGELLDLAGRRLRAIWTPGHTPGHVCLHLEEDHPAGLRGNGRLFSGDHLLPGITP
                     HIGLYEDPDDATVTDPLGDYLDSLERVARLDPAEILPAHQHAFTDAPARVGSLVAHHEE
                     RLTGLGALLAEPRTAWQLAEHMEWNRPWAEIPYGSRNIAVSEAEAHVRRLVKLGRAEVV
                     PGGDPVTYVAV"
     regulatory      15967..16092
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            16214..17449
                     /locus_tag="KY5_RS12030"
                     /old_locus_tag="KY5_2393"
     CDS             16214..17449
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004988782.1"
                     /locus_tag="KY5_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2393"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_098242235.1"
                     /transl_table=11
                     /translation="MNVRRSAAVLAAVAVFGSAAAPAAFADDASPSPAALPSGLYGKTD
                     PKFDGVFRQSYALLAQSMEGVEPAEKAIDWLTGQQCASGGFAAYRADASAPCDSKTAVD
                     SNSTAAAVQALAGVGHEDKTLKKSVEWLKSVQNTDGGWGYNPGLPTDANSTGIVIGALV
                     AAGENPADVKSKDGKSAYDALPKLVMDCDKDGGAFGLADPKSGKLSPNADATAAGVLGS
                     LGRGLVVEPPKDRDATGSKCAKPDTATQAASNGVGYLLDTLGKTDDHLMSSMPGAKDKP
                     DFGNTADAVLALAAADQKERAKKSAEWLAKNSADWAKQSGPAAYAQLVFAANAAGMDAR
                     DFGGADLVKQLNATGPAPRSASKSPTGSASDSDEKKDDGGGVSVWWIIGVGMVAGIGIG
                     FLYSGNRKKQQP"
     gene            17446..18123
                     /locus_tag="KY5_RS12035"
                     /old_locus_tag="KY5_2394"
     CDS             17446..18123
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070570.1"
                     /locus_tag="KY5_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2394"
                     /product="SCO2322 family protein"
                     /protein_id="WP_098242236.1"
                     /transl_table=11
                     /translation="MTAGRARRARRQAVALLAALLCTLGVIAAAPAQAVGYRYWSFWER
                     DGDSWTYATQGPGTARPDDGDVQGFRFSVSDDSKDSAAPRGTADFDDICADRPAREGRK
                     RVALVIDFGRPGDAPKGEKPPAARTACAQVGEDATSAEALASVAKPLRYDSNALLCAIS
                     GYPKSGCGDQVSGDGTSKKDSPARADGDAGDGGGPSVGLIAGIAAVVVLGGAALWQARR
                     RRG"
     gene            18143..19297
                     /locus_tag="KY5_RS12040"
                     /old_locus_tag="KY5_2395"
     CDS             18143..19297
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539164.1"
                     /locus_tag="KY5_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2395"
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="WP_098242237.1"
                     /transl_table=11
                     /translation="MTDHGSGAPGALGRRLAPAAHRSNALHPGAWWIWALGLGTAASRT
                     TNPLLIGLLIGVAGYVVAARRSSAPWAKSYGAFVKLGLVVIGIRLVFAIVLGSPIPGTH
                     VLVTLPEVPLPDWAKGVRIGGRVTAEGLLFALYDGIRLAGLLICVGAANALASPARLLK
                     SLPGALYEAGVAVVVAMTFAPNLITDVQRLRAARRLRGRPDSGIRGLLQVGLPVLEGAL
                     ERSVALAAAMDARGFGRSAAVPVAVRRATAVLTLGGLMGVCVGTYGLLTAQGAAYGLPV
                     LAAGLLAALGGLRLGGRRAVRTRYRPDRWGARAWAVAGSGIAVAGLMVLASSYGVAALQ
                     PGVVPLVAPTLPLWPAAAVLIGLLPAFVAPVPADSSPTVPKETS"
     gene            19294..21048
                     /locus_tag="KY5_RS12045"
                     /old_locus_tag="KY5_2396"
     CDS             19294..21048
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518431.1"
                     /locus_tag="KY5_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2396"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_098242238.1"
                     /transl_table=11
                     /translation="MIRFEDVSVTYEGSAGPTVRGVDLTVPEGELVLLVGPSGVGKSTL
                     LGTVSGLVPHFTGGTLRGRVTVAGRDTRTHKPRELADVVGTVGQDPLSHFVTDTVEDEL
                     AYGMESLGLAPDVMRRRVEETLDLLGLADLRDRPIATLSGGQQQRVAIGSVLTPHPQVL
                     VLDEPTSALDPAAAEEVLAVLQRLVHDLGTTVLMAEHRLERVVQYADQVLLLASPGEPP
                     VLGDPATLMARSPVHPPVVALGRIAGWSPLPLTVRDARRKAGPLRERLAQAAPERPGEH
                     APGDRPRPSGDRAAGKTGDPAPGRRPRLRRARAAAPTGAHREPGASVHAALVDRLAVRR
                     GRVEALRRVDLAVTPGETVALMGRNGAGKSTLLSTLVGLLEPTSGTVRVGGAAPHRTAP
                     RQLIRHVGLVPQEPRDLLYADTVGAECASADRDADAAPGACRALVSELLPGIADDTHPR
                     DLSEGQRLALALAIVLTARPPLLLLDEPTRGLDYAAKARLATVLRGLAAEGHAIVLATH
                     DVELAAEIAHRVVILADGEIVADGPTPEIVVSSPSFAPQVTKILAPHEWLTVSQVRRAL
                     GAAGQDPS"
     gene            21045..21881
                     /locus_tag="KY5_RS12050"
                     /old_locus_tag="KY5_2397"
     CDS             21045..21881
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839062.1"
                     /locus_tag="KY5_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2397"
                     /product="ECF transporter S component"
                     /protein_id="WP_098242239.1"
                     /transl_table=11
                     /translation="MTAAPTGQAQARPIRLGRRSIAALALVTAVGVAAFGWPLLAGAGS
                     GLSDHAQDAPWLFAALLPLLLAVVVATIADVGLDAKAIAMLGVLAAAGAALRPLGAGTA
                     GIEPMFFLMVLSGRVLGPGFGFVLGSVSMFASALLTGGVGPWMPFQMLSMGWVCMGAGL
                     LPGPDTLRGRRELWLLAAYGAVSSVLYGTVMNLQGWPYLGGLATGVSFVPGDPLADNLG
                     RFIAYCLATSLGWDLPRAVVTVLLSLTLGPAVLKALRRATRRAAFEAPVTFEAPKP"
     misc_feature    complement(22017..22032)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.24"
                     /tool="antismash"
     misc_feature    22057..22072
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            22245..22700
                     /locus_tag="KY5_RS12055"
                     /old_locus_tag="KY5_2398"
     CDS             22245..22700
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006137668.1"
                     /locus_tag="KY5_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_2398"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_234362702.1"
                     /transl_table=11
                     /translation="MSASLIRRIASPKKAITGGLVAAAATGMVFAAAPAQAATPTTAKA
                     AVPAAAPAAAPASAQAVAKQMIPDAAQYQAFSNIVAHESGWNHTATNSSSGAYGLVQAL
                     PGSKMASAGSDWKTNPATQIKWGLDYMNSRYGSPVGAWNFWQANGWY"
ORIGIN
        1 cggtcaaggc catgctcggc ttctacatcg gcggcatggg tcacgccgcc cgcaacttcc
       61 acgccgacct gatggcgcgc atgggatacg aggaggaggc caggcgcatc caggagctgt
      121 tcctcgccgg gcgcaggcag gaggcggtgc tcgccgtgcc ggacgccttc gccgacgaga
      181 tctcgctggt cgggccgcgc gcccgcatcg ccgagcgcct ggagctgtgg cgcaagggcc
      241 cggtgacgga cctgctggta ctggcccccg acccactgac cctgcgcacc ctggccgaac
      301 tcaactccta ggcgccgcct accccttggc gagctcaccc gccgacggca ccttgtcctt
      361 gacctctgcg cccgcgctgc tccccgcgcc cttcacgtcg ttgatgatgc cgtcgaagga
      421 gttcacgatc gagtccgtgc cttcgccctt gcggagcttg gacggcaggt ccttcagcgc
      481 gtcgatgccc gccgagaggg gcgccacggc cttggccagg gtcgggtcgc cctgggcgtt
      541 cttcgtcgcc gccttcagcc tgttgtacgt gaaggcgccc gcgagaccgg ccttgatcag
      601 ggcgaacctg cggccgtccg cgccgctctt gaacttcccc gcgcgaaacg gcttcacgat
      661 ccactggtac gtcgcccccg ccgcgagccc cgcgttggcc acgaagcggg tcttggcgaa
      721 cttctgcttc tctgccgagc tggacccggt cggcgtcgcc gcgctgtcct tgtcgtcgtc
      781 gttgcaggcg gtcgcgccca ccaggagcgt gcagcacagg gtgagggaga ctccggcgcg
      841 gcggacggat acggggctga gcacggcagc ggcctcctga ggtgagcggt cctcccggca
      901 gcctcacccc ggccgcgggg tgccgccacc cgggcgagcc cgtacgggtt ccttccgggt
      961 ttcaacgggg gcaggcccgg tacccgcccc tcatgtctcc ccgaacccgg aacacccgtg
     1021 gcaccaacga ggcagcgagg gtcatcgcga tcgtcgcgga cgtcatggcc ttcatcctcg
     1081 gcctgtggat cctgatgtac ctcctcgacg cgaaccgcgc caacgacctc gtccagttcg
     1141 tgcacgacgt ggcccgctgg ctcgcgggct ggtcgcacga cctgttcacg ttcgacgcgg
     1201 catgggcgag ggtcgtcgcg ggctacggcc tggcggcgat cgtgtacctg ttcatcggcc
     1261 acgcgatagc gggccgcctg cgccgctact gaagcgctcc gcgggacgcg tcgctcgtct
     1321 gcggctgcgt cgtggctgag cgcgcagttc cccgcgcccc ttcggggcgc gaccggcttc
     1381 cgggcccctt taggggcgcg gggaactgcg cgctcagccc gagcgaaccc gcggccgccc
     1441 cgcgaggggc ctcagcaaca atccggatcc agccccccgg gcaaccgctc cccggagaac
     1501 accgcacacg tcgcctcgtc cccgcccaac gcggcaaccg caaggagcaa cgaccccgcc
     1561 gtccacgtgg tcagctcctc gggccagacc gcctcgtcgt cgtagacgaa gcccgtccag
     1621 tagagacccg tcgccgggtc acgcaggtgc tggatggact ggaggatgtc cagggcccgg
     1681 tccgactcgc ccaacgccca gagcgccagg gcgagttccg cgctctcgcc gcccgtcacc
     1741 caggcgttgg gcacgacgca gcgcacgccg aggccgggca cgacgaagcg gtcccagccc
     1801 tcctctatgc gggacttggc cgccgcgccg gtcagggcgc cgccgaggac cgggtagtac
     1861 cagtccatcg agtagcggtc cttgtcgagg aagcgctcgg ggtggtggcg gatggcgtgc
     1921 gcgagcgcgc ccgtcgccag ctcccagtcg ggctgggcct cgtcacgctg ctcggcgatc
     1981 gcgagcgcgc agcgcagcgc ctggtggatc gaggacgagc cggtgagcag cgcgtcggtc
     2041 accggcgtgc cgtcgggctc gcgcttccag ccgatctggc cgcctggctg ctggagcgcg
     2101 aggacgaact cgacggctcc gaccacggcg ggccacatgc ggtcgaggaa cgactcgtcg
     2161 ccggtggcga ggtagtggtg ccagacgccg acggcgaggt acgcgcagaa gttggtctcg
     2221 cggccccggt cggtgatgtc gtgcggatcg ccgtcgcggt aggccgcgta ccaggagccg
     2281 tccgggttct ggtggcgcgc gagccagtcg taggcccgct cggcggccgc gtgctcgccc
     2341 gcggcgtcca gggccatggc ggcctcggtg tggtcccacg ggtcgaggtg gtggcccctg
     2401 aaccacggga tggcgccgtc ctcgcgctgc acggcgagga tgccgcggac cgtcgccgcg
     2461 gcctgatcgg ccgtcaggac gccgggcagg acgaggtgtt cggtccgctc ggggctcgtc
     2521 acttggcgtc cgccacggac tccgcggcgg cgacgggaag gtgcggcttg gtcgcgtacg
     2581 ccacgaagct cttgccgacg acggggttga gcaactgctc ggcgacccgg gtggcgagcg
     2641 gcttcttcat gatgtcccag accaggagct tgtggtacgc gcgcaccggc agcgccttgt
     2701 cgttgtcgac gccgaaggcg cacttcagcc accagtaggg cgagtgcagg gcgtgcgcgt
     2761 ggtgcgtgcc gtacggcttg aggcccgact cccgcatctt gccgaggagt tcgtcggcct
     2821 tgtagatgcg gatgtggccg ccctcgacct cgtggtaggc gtcgctgagc gtccagcaga
     2881 ccttctcggg gccgtagcgc gggacggtga cggcgatgcg gccgccgggc ttgaggaccc
     2941 ggaccatctc ggcgaggacg cccttgtcgt ccgggatgtg ctccatgacc tcggagatga
     3001 tcacgacgtc gaaggaggcg tcggggaagg gcaggttgag cgcgtcgccc tccatcgcgg
     3061 tggccgtcgc gcccgcgggg gcctcgcccg cctccttcat cgcggcgaac cacttggcga
     3121 cctcgcggat ctcctcggcg ttctggtcga gggccaccac ctgggcgccc cgccggtaac
     3181 actcgaaggc gtgccggccc gcgccgcagc ccaggtcgag cacgcggtcg cctgcggcga
     3241 gcgggaagcg ggtgaagtcg acggtcagca cgtggccctg ctttcgtggt gaggtcctgc
     3301 aacttcgggg gcggccgcgg cggtggcggc cgggagggcg tggccgcgtg cgacggcacg
     3361 ggtggcgccg cgtcccgcgg agcggtcgat cgccgcgcgg tagagctcgg cggtgccctg
     3421 ggcggcgcgg gcccaggtga acctgtcgag cacccgcgca cgtcccgccg cgccgagcct
     3481 ggcccgcagc ccggcgtcgc cgaggagccg gttcaggccg agggcgagcg cctccgggtc
     3541 gccgggcggc accgcgacac aggtctcgcc gtcggggccc gcgacctccg ggatcgcgcc
     3601 gccggtggtc gcgaggagcg gggtgccggt ggccatcgcc tcggccgcgg gcagcgagaa
     3661 cccctcgtac agggagggga cgcaggcgat ctgcgccgag cggaccaggt cgacgagttc
     3721 ggcgtcggtg atgcccttga cgaactcgat cgagcccgcg aggccgtgcc gctcgatggc
     3781 ctgggcgacc gggccgtcct ctgcgcgctt gccgaccacg acgagatggg cggcggggtt
     3841 ctcggtgcgc accttggcga gcgcctcgac caggtggatg aggcccttga gggggacgtc
     3901 ggcactggag gtcgtcacga tccggcccgg cacctcggcg accgaggggt cgggcgagaa
     3961 gaggtcggtg tcggcgccga tgtggacgac gtcgatgcgg tcgtcgcgta cgccgaggtg
     4021 gtcgatgatc tcctggcgcg aggtgccgga gacggtgagc accgagggca ggcggcgcgc
     4081 gacgcgcttc tgcatgcggg tgaacgcgta ccaacggcgc accgacatgc ggcgcttgag
     4141 gtcgggcgcg gcgtcgagtt cgagccgccg gtcgacggtg atggggtggt ggatcgtggt
     4201 gaccaggggg gcgccgaggt cgcccaacag gccgtatccc agggtctggt tgtcgtgcac
     4261 gacgtcgaac tcgccgcgcc ttgcgcgcag atgacggcgg gcgcgcaggc tgaacgtggc
     4321 gggctcgggg aagccgccgg tccacatcgt cgccacttcg agggcgtcca cccagtcgcg
     4381 gtactcgtcg cgccccgggg tgcggaaggg gtcgggcgag cggtagaggt ccaggctcgg
     4441 gagctcggtg aggctgagcc cttcgaggcc ctcgccctcg tcgagcaccg gatagggctg
     4501 cgcgccgatc acctcgacgg tgtggccgag ccggacgagc tcgcgcgaca ggtggcgtac
     4561 gtagacgccc tgtcccccgc agaacgggtt ccctttgtac gtcaggagag cgatgcgcaa
     4621 cggacgatca ccttcggcgg ccgagccctt ccgggggcct gcctccatgg cctcagcggt
     4681 cactctcggt ccccttctcc tgcagttgtc cgcgaggtta cgccgggacg gtaatctaga
     4741 acaagtttca gacttgatcg ctgaatgatc gctgaacgag ctctgaatct accggcaggt
     4801 aggcgagctg taaggcccgg atcaggtgat tcgcgccacg gcgggctccc tgccatgctg
     4861 tgcgatctcg tgaggcgttt tcggaggggc agcacatgac agcggaagcc aagacaggga
     4921 gccctgcgac gccgcccctc accgagcgcc aggaggcgcg ccgccgccgc atcctgcacg
     4981 cgagcgccca actggccagc aggggcgggt tcgacgcggt gcagatgcgg gaggtcgccg
     5041 aggccgccgg cgtcgcgctc ggcacgctct accgctactt cccctccaag gtgcacctgc
     5101 tcgtcgccac catgcaggac cagctgcagc acatgcacac cacgatcagg aagcgccccc
     5161 cggcgggcga gacccccgcc gagcgggtcg ccgagacgct gatgcgcgcc ttccgcgccc
     5221 tccagcgcga gccgcacctc gcggacgcca tggtgcgggc cctgaccttc gccgaccggt
     5281 cggtgagccc cgaggtcgac accgtctcgc ggctgaccac ggcgatcatc ctggacgcga
     5341 tgggactggc ggagccgccg accgcgcagc agctctcggc ggtgcgggtg atcgagcaca
     5401 cctggcactc cgcgctgatc acctggctct ccggaagggc gtcgatcgcc caggtgaaga
     5461 tcgacatcga gacggtctgc cgcctgatcg acctcacggc gaccccccga gcgtgacagg
     5521 ggggcgcaca ggcgcccggc aaatgcgccc ccaaacaccc ccttggccag ttctcagtgt
     5581 cactacgggg gtactcaccg ctattaatgg tctgcgtcct tgaagggggc aaccggagcg
     5641 ggagctggag gggcagagcg tgatccgggt acttctcgtg cacgacgcct gtctactgcg
     5701 attagccctg gcggaacgtc tcgcccggga acctgacttg gaggtgttcc atgcgccgtg
     5761 gtcacaggct cacggtcggc agcgcacggt acgacccgat ctctgcgtgg tggatctcga
     5821 cgacgagtcg acgtacgcgc tcacgccgct caccgagctg accgggccct cggcgcacgg
     5881 tcgcggctgc cgggtcctgg tgctcgccac ggccaaccgg ccggggcagc tgcgccgcgc
     5941 cgcggaggcg gacgcgctcg gctacgtgaa caaggcgagc cagccggaac ggctgatcac
     6001 cggcatcaga caggtggcgg cgggccagcg gttcgtcgac gactccctgg ggttcggctt
     6061 cctcaaggcc gcccaaatgc cgctgacgca aagggagttg agcgtcctgt cactcgccgc
     6121 gcgaggcgct tctgtcgccg agatcgccca cagtctccat ctctccaacg gaacggtgcg
     6181 caactacatg gccgcgatca cccggaagac cggggcgcgg aacaggatcg acgccataag
     6241 gatctcgcag ggcgagggct gggtctgagg cgacgccgcc ccggtcaccg ccccggcccc
     6301 cgccccagtc accggccccg ttgaggtccc ggtacagggg cgaacgctcc atcagctcgt
     6361 cgtgccgacc gcacagggcg tgcaccccgt ccatcaccag gacccggtcg gcgcggcggg
     6421 ccgagctgat gcggtgcgcg atcaccacca gggtgccgcc ggggcgcgcc gcgaacgcgc
     6481 gctcggcgcg ggactccgcg accgggtcga ggtgacaggt cgcctcgtcg aggatcgcga
     6541 gcggggcgta cgcgacgtac gcgcgggtca gcgcgatcaa ctggcgctcc cccgccgaca
     6601 gttcacccgg tacgagctcg gtgtcgagcc cgccgaggcg ggcgacgagc ggcgcgagtc
     6661 ccacggcctc ggccgcgccg gtcagctcgg actccggcac cggctccgcc cgcaggtact
     6721 ccaggttctc cctgagcgtc cccgtgaaga cgtacgcctc ctgaggaatg agcacgcgcc
     6781 gcccgacggc tccttcccca cgcaccccag cgccctccac acgcacctct cccgcgtccg
     6841 gcacgagcaa cccggcaaca attccggcca aggtggactt cccgatccca ctgggtccca
     6901 ccacggcgag gtgctcgccc ctggccacac tgagccccag gttccgcagc acgggctcgg
     6961 cgtgcggacc ataggcgaag gtgacggagg agagctccag cgcgggcccc tgacccgcgc
     7021 ggcccgcctc ggcgccgcca ccgctccccg gcccctccca catgagccgc cgcagcacga
     7081 tcgccaggcg ggagccgctc gcgccgaggc cgtggaccag gttgtggagg gcggggagca
     7141 gggcctgggt gacgtaggcc agggctccca ccagggcgcc cggggtcact ccattgtcca
     7201 ggagccaggg ggccgtggtc aggagcagga tcagggggag ctggccgccg atcgccaggg
     7261 acgcggtgcg caggacgccc cagcgggcca gggccgcggc cgtcctgtac tcccgggcga
     7321 cgccccggcc caggtcggcg gcgacgtcgt cttccgcgcc cgccgccgtg acgtcccgca
     7381 acccggggca gaccacgccc agccgggccg ccagctcctc gtccgcgacg aggaactcct
     7441 cctggcggcg ggccagcgga cgcagcgtcg cgacgaagag ggcgatgccc gcgaggagcg
     7501 gcggcgcgac caccaggagc aggagcgggt ccagggagaa gaggccgacc agggcgccga
     7561 ccgccgtgaa gacgaaggag cgggagacca tgatcaggcc cgcgaaggtg tccctggcga
     7621 tctccacctg ctgggtgagc cgggacacgg cggcactgtc cgcgtcgtgc aggccccgcc
     7681 cgacgacctg gcgcaccagg gagtccctga gcggttccac caggtcggcg acggcgcggt
     7741 acacgcggct cgtgccgtag gcggcgacca ccacaccgag cccggccccg ccgagccacc
     7801 agaggccgac cgcctcgtgg cccgcgagga acccgtcgtc cagggcgcgc gcgagggcgt
     7861 acccggtgag gaacgtctgg ccggtctcca ggacggacca gagcgcgagc cgcagcacca
     7921 ccggccactt gcgccacagg aagcggacgc cacggcggta gggaccctgg gcgtggggag
     7981 ggttcacgcg ccgaacacct cccggtactc cgggcgttcc cacagttcct cgtgggtgcc
     8041 caccgcccgg atccggccct cgtggagcca ggccaccgcg tccgcgcggg ccgccgtcgc
     8101 ggcccggtgg gcgatgatca ggcggctgcg gtgcggggtg tggtggagca gcgcgtcggc
     8161 gatgtggtgt tcggtgaccg tgtccaggct ggacatggcg tcgtccagga tcagcagccg
     8221 cccgccgcgc gcgaacgccc gtgccagacc gaggcgttgg gactcgccgc cggagagcgg
     8281 cgcctgtccg caaggggtgg cgtagccgtc ggggaggcgg gtgatgaagg tgtcggcgcg
     8341 ggcggcgcgg gccgcctcgc ggatccgtcc cggcgtcgga cgcggggcgc cgaggccgat
     8401 cgtgtcctcc agggtcgtcc ccagcagcgc gggccgctcg aaggcgtagc cgacctcgcg
     8461 gcgcagctcc tgcctgccga gcgagcgcag cgggaccccg tcgaggcgca cctccccctc
     8521 gtcggggtcg gcgagccgcc cggcgagcgc ggcgagcagc gatttgcccg cgcccgagcg
     8581 gccgaccacg gcgagcgtgg tgcccgcggg caccgtcagg tcgacgccgt cgaggacggt
     8641 acgtccgccc cggctcgcca tgacgccgcg cagctccaac aggccgccct cggggggcag
     8701 ttctgcttcg ccgtacgacg tcgggggttc ggtgaggact tcctccaggc ggcgggccgc
     8761 ggccctggcc cgcaccagac cgcccaactg tcccacgagc atgccgatcc cggtggccag
     8821 caccgcgtac cgggacgcgg cgagcaggtc gccgaccgag atgcggtgcc ggagcagcag
     8881 cagccccgcg accgcggcga ccgcgatctg caacagcggc gcgaccgcga cggcctgcgc
     8941 ctgggagcgg ccctgaaggc gccacatccg ccgtccctga cggccgagtt cgggcagttc
     9001 gccgaggacg cgcgccgcct ccttgtcctg cgtgtgcgcg gcggcgacgg tgcgcgcccc
     9061 gccgatcgcc tcgctcaggc gtcccgcgat gttcccctgg acccgctggt agcgcgccac
     9121 gcagtcggag gagacgcgca cgaaggtccg caggagcagg aagagcacgg gcgcgccgac
     9181 gaggaacacc gcggcgagcc agccgtcgat gagcgcgagg gccaccacgg cgccgacggg
     9241 cgtgaccagg gcggccagga gcgcggcgaa ggtggcgggc gcgatgcccg cgtgcgccgc
     9301 gttgtcgatg aggcgcgcca ccaggtcgcc gtgggcgaag cgcgcggtgg tgcgcggtcc
     9361 gacggcgagc acgtgtccgg tgacgcggcc gcgcagccag gcggtggtgc gggcgttggt
     9421 ggtgccggtg aggacgccgt cgagcgcgtc gaggacggcg ctcgcggtga tcagcgcggc
     9481 gcacgcggcg atccagcggg tggcgtcggc gtcagccgcg cccgtcaggt gtccggtcag
     9541 gacggcgtcc agggcgcggc cgatcgcgag cggcaggagc agtcccgcgc ccgcgctcgc
     9601 cagggcgcac agcgccagga tcacgcagcg gagggcgctg tggcgggcgg ccgcgcccaa
     9661 caggtgtgcg tcgtgggtgg gttggtgcgg acggggggtc gtcgtcgcca tgcggtccgg
     9721 gtcctcgtcg ccttcgtcgc gcaggtctca caacggtcgg cccgggcggg cccctcacgg
     9781 ggcgccgccc gggccttcag accgtgtcgg tcagatgcgg cgaggcatca gagacacaga
     9841 acgatgctcg cgtcgctcca gcacagcagg aggctggcca cactgccgcc gccaccgtga
     9901 ccgccaccgg tcagctcgtc ggattccatg ctctgcaggt cgagaagtgc catgaacttc
     9961 cctctcttta gggggacttg tgaggtccct atgggcggtg tcacgacccc gcggtgtcgc
    10021 gggaccggct ctggggccgc cggatcggcg gcaggaaggg gacgtgcgct ccggtgtcgc
    10081 cgagcgcgct ggcgagcgcg aggaggcagc ccgccgtccc ggtgttgagg tccatggaga
    10141 ggcgcagcat ctggttgccg gggaaggcca gttggcccgc gtacgacatc gcgaaccagc
    10201 cgagctcctc gatctgcgcg gccacgtcct cgggcgtgat gcccggcgtg gtgctgcggt
    10261 tgacgtgcag gagcagtcct gcccgcccct ggaagaggcc cggctgcacg cagaagcggg
    10321 agctcgccgc ggccaggatg ccgggacgtg ccgcctcgaa gcgttcgtcg tcgcggtgcg
    10381 cgaggtagtc gtcgatgacc atgccgatgc cgacgctgcc gtcgccgagg tagggcatgg
    10441 tgcgccagcc ctcgttcacg gcgaggctgc cgtcccgctt ctgggtcacg cactggtcga
    10501 ggtcggcacg cagggcgcgg gccgcgaggt cgaggagggc ggggtcgccg cctcgctcgt
    10561 acaggcgcag gaagagcagg gcgggcccgg tggcgccgcg cagcagtccg gccctgcgcc
    10621 tgccgttctt cggcggctct tcggaggcga gccgttcgcc gagcagctcg gcggcgcgca
    10681 gcgcgtactg gccgagcgtg cgctcgccgg tgctctccgc gagggagtcg agggcgaggc
    10741 cgactccggc gaggccgccg tacaggtcgg aggggaggcg ctgccagcgt tcctggagga
    10801 tgagttccgt caggtccagc gcgcgctcgc ggtggccgag cctgtccagg acgtgggcga
    10861 tgcccgcgag tccgtcgtgg agtcccaacg gggtgcccgc cggggcgggt cggctgtggt
    10921 cgaggagcca gcgctcaccc tcctcgtacc gttccgcgcc gctctcggcg agggcgagga
    10981 ggacaccggc cgcgccgtgc gcgaggccga gcccgccgcc gtcggcgaac tgcgcgatgt
    11041 cgccggggaa gagccggtcg tcgcgctccg gggtggcgga cgcgaggatg gccttgacca
    11101 tcgagtcgcg gctgtagggc cagtcggccg ggtcgaccag cggtgcggcc acccgcgccg
    11161 cgggcccggc ggcgccggtc gcgcccccct tcgggaggcc gctctccagg gcctccgtgt
    11221 ctcccgctcc gcggaccggc gcccgctcgt ccccgttggc cccgggggtc ccgccgtccc
    11281 cgccgggtgc gccacgctcg atctcggcca cggcctcggc caggaactcg gcgggcacgt
    11341 cggggaattc ggtggcgatc acctgcgcga agtgcgcggc cttaccccgg tcgatggaga
    11401 gcagggtggt gatcggcagg aagagggcga gccgcaggca ggcgagtgcg tagcggtcga
    11461 cgtccacgcc cgtgcggtcc ggcggcgcga ggaatccggg gtgcgcgacg atctggcgcc
    11521 cctcgtcgcc gacggccgcc gcggcctcga agtcgagcag cgagacggac tgttcgtcgg
    11581 gggcgaccat gatgttgaac aggtgcaggt cgttgaagac gacgccccgc tcgtgcacgg
    11641 cggtgacggc ttcctcgacg gcccggtgca tgcgcagcgc ccaggccgtg tactccgata
    11701 tgtcggcggc gtcgggctcg ctggtgcaca gcggatgccg gtgcgcgaag aaggagttga
    11761 gggtggagcc ctccaggaag tccatgacga ggaagcggtg ttcgccgagg aggaaccagt
    11821 cgcgcacctc gggcgccaca ccgagcccgg agagcttctg cagggcgtcc cgctcgcgtt
    11881 cgaggcgggc cacggcgtcg gcgccgtcgg aggcgaggcc cgcgtgcgga cggccctcct
    11941 tgaggacgac cttgctgccg tcgcgggtgt cggtgcccgc gtagaccccg ccgccgttgg
    12001 agaagtgcag cgccttctcg atgcggtacg gcaggtcgcc gacggtcgtc gtgttgcgcg
    12061 cggcgagcgc cggttcgagg aagtcgggca gcttcaccca cgcggggacc ttgaaggcgg
    12121 ggccccggtc gtcgggcacg agcttgccct cgccgtcctc cacggcgggc acgagggtgc
    12181 ccttgccgtc gtcgcacatg cggcgggtga aggcgccgta cctgacgtac agcggcccct
    12241 gctcccagcg caggtcggtg aggatgtacg gcccttcgaa cccttcgagg agcttgccca
    12301 actcatcgag cagctcgtgc agttggttct cgtcggccgg gtagacggtg gcgaacttgc
    12361 cgctcatgtc acggcccgcg tacttgctgt tgcgcaggtg cagcaggtgc ttggccggca
    12421 cgaacttgaa ggggaccgag cgcggcacgc agtggtccca cacgagggcc gcgatccggt
    12481 cggcgttctc cagggtggcg gagacgtgga tcttccagcc ctgctggggc gtggggagcg
    12541 gggccccgtc gtcgccgatc gggacgaggg agaaccagtc accggcgcgt gcggagcgcc
    12601 acccttcggg caccgggcgc tgggatacgg ggaacgcgcg ggcaccgctt cgggtgcccg
    12661 tggacgacag ccggtccggg gtctcgtaga agaatctgtc ggccagacag tagacctcgt
    12721 accgcttgtc catggtgtcc cctccctgct cggcgtggca gagagatttc caggacggaa
    12781 acgggcggaa cagtaacgac tgtcaccaga tcaccatgcg gaacgcatgc gtaaagtggc
    12841 gttcgccctt gttcgagcac acagaatatc cagaggatcg acacatggcg atgcccgcgt
    12901 cgcgatggtt cgaactcgac gcgggcatcg ggtgattgag ggggcgaagc cgccctccgg
    12961 gctggtcctc agggctagtc ctccggcggg aagacgacct ctccgctgtc ggcgagggtg
    13021 atcgtgatcg cctcgaccgg gcagccctcg gcggcctcga gcaccttctc gttggcgtcg
    13081 gtgtcggggt gggtgggatg cgactgacgg gcggtgtcga gggtgaagcc gtcgggcgcg
    13141 gtgcccacgc acatcccgga gccgatgcag accgaccggt cgacctcgac gtgccagcgg
    13201 tcccccatca ggcgccactc ccctcgtatc cggcggggag gtggatcatc tggtgctcga
    13261 agtactcggc gtacccctcg ggcccgaact cccgccccag accggagttc ttgaagcccc
    13321 cgaagggccc gagcatgtcg aggctgaagg tgttcacgga gtacgtcccg gtgcgcacct
    13381 gccgtgcgac gtcgatgccg cgctcgacgt cggccgtcca cacgctgccg ctgagcccgt
    13441 agtcggagtc gttggcgatc ttcaccgcct cgtcctgttc gccgtacggc aggaggcaga
    13501 tgacggggcc gaagatctcc tcgcgggcga cgcgcatgga gttgtcgacg ccgcccagga
    13561 gcgtcggctc gacgtaccac ccctgatcga gcccggccgg gcggccgccg cccgcgagga
    13621 tcttggcgcc ctcctcctgg ccgatgcgga tgtagtccag ggagcgctgc tgctgcctct
    13681 tggcgacgag cgggcccagc tcggtggcgg ggtcgagggg gtcgccgacc ttgagggcgg
    13741 acgcggcggc ggcgaacgcc tcggcgaact cgtcgtagcg ggtgcgcggc acgaggatgc
    13801 gggtctgggc cacgcacgcc tggccgttga tcatccaggc gaagggggtg atgcccgcga
    13861 cggcggtggc cgcgtcggcg tccggcagga tgaccgcggc ggacttgccg ccgagctcca
    13921 gggtgacccg ggtgaggttg cgggccgcga cctccatgac gcgcttgccc gccgcgacgg
    13981 atccggtgaa ggagaccttg tcgacgccgg ggtgcgcgac gaggtactcg ctgacctcgc
    14041 ggtccgcgga gatgacggag aggacgccct gcggcagccc ggcctctgcg gctatctcgg
    14101 ccaggatgta ggcgtccagg ggtgcctcgg gcgaggtctt gaggatcacc gggcacccgg
    14161 cgagcagcgc gggggcgagc ttggccgcgg cggtgaactg cgggacgttc caggggacga
    14221 cggccgcgac cacccccacc ggctcgcgcc gcacgaggag tttcccgagg acgccgtcgc
    14281 gtgcctcctc gtaggtgaag tcgcgggcca ccgtgatggc cgcgtcccac gccatcatcg
    14341 cggcgagcgc ctgcaccatc acgctggagg tgtacggggt gccgttctcc gagctgatgg
    14401 cgcgggcgat ctcctcgtgg cgtacggcga tcccgtcctt gatcttggtg acgacctcga
    14461 tccgctcgtc cagggtcatg cggcgccagg gcccgtcgtc gaacgccttg cgggcggtgg
    14521 cgacggcgcg gtccacgtcg gcgggggccg cgtgcggcac gcgggcgaag acctttccgg
    14581 tgtgcggcga cacgacgtcg atgacgccct tgccgagcgg gtccaccaac tccccgccga
    14641 tgaacagctg tccgtgttcc acgagctcgg tcatggctga ctgcctcctg cggagcgctt
    14701 tccgacaccg acttcctgac actgtttcag aactgatacc agttctagtt ggcggagtcc
    14761 acggaacgga cgcgcaaccg gccgcccatt ccgtcgactt gggcgactat tgaaactagt
    14821 tctagttata gtgacggcac ccggcgacga gagacgaggc cctcatgacc ccgcaggtga
    14881 cggacccgcc ggtgatcgag cacggcggcg gcgtctggag catcaaggtc ccgatccccg
    14941 acaaccccct cggcttcacc ctcgtccacc tcctggacac cgaccgcggc gccgtcctcg
    15001 tcgacaccgg ctgggacgac ccggcctcct ggcacacgct ggccgacggg ctcgccgcgt
    15061 gcggcgtcgc cgtcgccgac gtgcacggcg tggtcatcac ccaccaccac cccgaccacc
    15121 acggcctgtc cgcgaaggtc cgcgaggcgt cgggcgcgtg gatcgcgatg cacgaggcgg
    15181 acgcctccgt ggtgcgccgc acccgctcca acccgcccga gcggtggtac gcctacatgg
    15241 cggcgaagct cacggccgcg ggcgcccccg aggagcacgt cgcgccgctg gtccgcgccg
    15301 ccgaggaggg ccgccccagg aggctccccg gcctcgaccc cgccctgccc gaccgcgaca
    15361 tcgtccccgg cgagctcctc gacctggcgg gccgccgcct gcgggcgatc tggaccccgg
    15421 gccacacccc cggccacgtc tgcctgcacc tggaggagga ccacccggcc ggactcaggg
    15481 gcaacggccg cctcttctcc ggcgaccacc tgctgcccgg catcaccccg cacatcggcc
    15541 tgtacgagga ccccgacgac gccacggtca ccgatcccct cggcgactac ctcgactccc
    15601 tggaacgggt ggcccgcctc gacccggccg agatcctccc cgcccaccag cacgccttca
    15661 ccgacgcccc cgcccgcgtc ggctcgctcg tcgcccacca cgaggagcgc ctcaccgggc
    15721 tgggcgccct cctcgccgag ccccgcaccg cctggcagct cgccgagcac atggagtgga
    15781 accggccctg ggccgagatc ccctacggct cgcgcaacat cgccgtatcg gaagcggagg
    15841 cccatgtgcg gcgcctggtg aagctgggcc gcgccgaggt cgtgccgggc ggcgacccgg
    15901 tgacgtacgt ggcggtgtga atccccgggc gtggatcccg tgcccggccg ctcctggtac
    15961 gggccggtag agtgggcgcg tcgtcctcac gcccgtacag ggggaagccg gtgcgaatcc
    16021 ggcgctgacc cgcagccgta tgaccgcttc cagcggagag ccggaatgcc cggtgcggaa
    16081 cgtgaccggc tcgcttcatc ggaccccgat gagcggcacc gtcgaggtat acggagccgg
    16141 agccgcccgg aagccgtgct cgcaacggtc cgtgccgccc cgctccccgc agggagaggc
    16201 aacccgccgc atcatgaacg ttcgccgcag cgcagcggtc ctggccgccg tcgccgtgtt
    16261 cggctcggcc gcagcaccgg cagccttcgc ggacgacgcc tcgccgtcgc ccgccgcgct
    16321 cccctcgggc ctctacggca agaccgaccc caagttcgac ggcgtcttcc gccagtcgta
    16381 cgccctgctc gcccagagca tggagggcgt cgagcccgcc gagaaggcca tcgactggct
    16441 gaccgggcag cagtgcgcga gcggcggctt cgcggcgtac cgcgcggacg cgagcgcgcc
    16501 gtgcgactcc aagaccgcgg tcgacagcaa ctccaccgcc gcggccgtgc aggcgctcgc
    16561 cggagtcggt cacgaggaca agacgctcaa gaagagcgtc gagtggctga agtccgtaca
    16621 gaacacggac ggtggctggg gctacaaccc gggcctgccc accgacgcga actccaccgg
    16681 catcgtgatc ggcgccctcg tcgcggcggg cgagaacccc gccgacgtga agtccaagga
    16741 cggcaagtcc gcctacgacg cgctgcccaa gctcgtcatg gactgcgaca aggacggcgg
    16801 cgccttcggc ctcgccgacc ccaagtccgg caagctctcg ccgaacgccg acgccaccgc
    16861 ggccggtgtg ctcggcagcc tcggcagggg cctcgtcgtg gagccgccca aggaccgcga
    16921 cgccaccggg tccaagtgcg cgaagcccga caccgcgacg caggcggcga gcaacggcgt
    16981 cggctacctc ctggacaccc tcggcaagac cgacgaccac ctgatgtcct cgatgccggg
    17041 cgccaaggac aagcccgact tcggcaacac cgccgacgcg gtgctcgcgc tcgcggccgc
    17101 cgaccagaag gagcgggcca agaagtccgc cgagtggctc gcgaagaact ccgcggactg
    17161 ggcgaagcag tcgggtcccg ccgcctacgc ccagctggtc ttcgccgcca acgcggcggg
    17221 gatggacgcc cgtgacttcg gcggcgccga cctggtgaag cagctcaacg ccacgggccc
    17281 ggccccgcgg tccgcgtcga agtcccccac cggctccgcc tccgactcgg acgagaagaa
    17341 ggacgacggc ggcggcgtca gcgtctggtg gatcatcggc gtcggcatgg tcgccggcat
    17401 cggcatcggc ttcctctaca gcggcaaccg caagaagcag cagccgtgac cgcgggccgt
    17461 gcgcggcgcg cgcggcggca ggccgtggcg ctcctcgccg cactgctctg cacgctcggc
    17521 gtcatcgccg ccgcgcccgc ccaggccgtg ggataccgct actggtcgtt ctgggagcgc
    17581 gacggcgaca gctggacgta cgccacgcag ggccccggca ccgcacgacc cgacgacggc
    17641 gacgtccagg gcttccgctt ctcggtctcc gacgactcca aggactccgc cgcgccgcgc
    17701 ggcacggcgg acttcgacga catctgcgcg gacaggcccg cacgggaagg ccgcaagcgg
    17761 gtcgccctcg tcatcgactt cggacggccg ggggacgccc ccaagggcga gaagccgccc
    17821 gcggccagga cggcctgcgc gcaggtcggc gaggacgcca ccagcgccga ggccctcgcc
    17881 tccgtcgcca agccgctgcg ctacgacagc aacgccctgc tctgcgccat ctccggctac
    17941 ccgaagtcgg gctgcggcga ccaggtgtcc ggcgacggca cgtcgaagaa ggactcaccc
    18001 gcgcgggccg acggcgacgc gggcgacggc ggcgggccct ccgtcggtct gatcgccggg
    18061 atcgccgccg tcgtggtgct cggcggcgcc gcgctctggc aggcccgccg tcgtcgcggc
    18121 tgacgcggcc gaggacagca cgatgacgga ccacggcagc ggcgcgcccg gcgccctcgg
    18181 gcggcgcctg gcccccgcgg cccaccggag caacgccctg catccgggcg cctggtggat
    18241 ctgggcgctc ggcctcggca ccgccgcgtc gcgcacgacc aatccgctcc tgatcggcct
    18301 gctgatcggc gtcgccggat acgtggtggc cgcgcggcgc tcgtccgcgc cgtgggcgaa
    18361 gtcgtacggc gcgttcgtga agctcggcct ggtcgtgatc gggatccggc tcgtcttcgc
    18421 gatcgtgctc ggctcgccga tccccggcac gcacgtcctc gtgacactgc ccgaggtccc
    18481 gctgcccgac tgggccaagg gggtccggat cggcggccgg gtcaccgcgg aggggctgct
    18541 cttcgcgctg tacgacggca tcaggctcgc gggcctgctg atctgcgtcg gcgccgcgaa
    18601 cgccctggcg agcccggcgc ggctgctcaa gtcgctgccc ggcgcgctct acgaggccgg
    18661 ggtcgccgtc gtggtggcga tgaccttcgc gccgaacctg atcaccgacg tgcagcggct
    18721 gcgggccgcg cggcggttgc gcgggcgccc cgacagcggc atcagagggc tcctccaggt
    18781 ggggctgccg gtcctcgaag gggcgctcga acgctcggtc gcgctggccg ccgcgatgga
    18841 cgcgcgcggc ttcggccgca gcgccgccgt gcccgtcgcg gtgcgcaggg ccaccgccgt
    18901 gctgacgctc ggcggactca tgggcgtgtg cgtcgggacg tacggactgc tgaccgcgca
    18961 gggcgccgcg tacggcctgc ccgtcctcgc cgccgggctg ctcgccgcgc tcggcgggct
    19021 caggctcggc ggccgcaggg ccgtgcgcac ccgctaccgg cccgaccggt ggggcgccag
    19081 ggcctgggcc gtcgccggtt cggggatcgc cgtcgcgggg ctgatggtcc tcgcctcgtc
    19141 gtacggcgtc gccgccctgc aacccggcgt cgtgccgctc gtcgcgccga cgctgccgct
    19201 gtggcccgcg gccgcggtgc tgatcggcct gctgcccgcc ttcgtcgcgc cggtgcccgc
    19261 cgattcctcc cccacggtcc ccaaggagac gtcatgatcc gcttcgagga cgtctccgtg
    19321 acgtacgagg gaagtgccgg gcccaccgtc cggggggtcg atctcaccgt ccccgagggc
    19381 gagctcgtgc tgctcgtggg cccctcgggg gtcggcaagt ccacgctgct cggtacggtc
    19441 agcgggctcg tgccgcactt caccgggggc accctgcgcg gccgggtgac ggtggcgggc
    19501 cgcgacaccc gtacgcacaa gccgcgcgaa ctggccgacg tcgtcggcac ggtgggccag
    19561 gacccgctct cgcacttcgt cacggacacc gtcgaggacg aactcgcgta cggcatggag
    19621 tcgctcgggc tcgcccccga cgtgatgcgc cgtcgcgtcg aggagaccct ggacctgctc
    19681 ggcctcgccg acctgcgcga ccgccccatc gcgacgctct ccggcggcca gcagcagcgc
    19741 gtcgcgatcg gctcggtcct caccccgcac ccgcaggtcc tcgtcctcga cgagccgacc
    19801 tccgccctgg acccggccgc cgccgaagag gtgctcgcgg tgctgcaacg cctcgtccac
    19861 gacctcggca ccacggtcct gatggccgag caccgcctgg aacgcgtcgt ccagtacgcg
    19921 gaccaggtcc tgctgctcgc gtcccccggc gagcccccgg tactcggcga ccccgccacg
    19981 ctgatggccc gctcccccgt ccaccccccg gtggtggccc tcggcaggat cgcgggctgg
    20041 tcccccctgc ccctgacggt gcgcgacgcc cgccgcaagg cgggcccgct gcgggagcgc
    20101 ctcgcgcagg cggcgccgga acgtccgggc gagcacgcac cgggcgatcg cccgcgcccg
    20161 tcgggggacc gcgcggcagg aaagaccggc gacccggcac ccggccgccg gccgcgcctg
    20221 cgcagggccc gcgcggccgc gccgaccggt gcgcaccggg agccaggggc ctcggtccac
    20281 gccgccctgg tcgaccggct cgccgtccgg cgcgggcgcg tcgaggcgct gcggcgggtc
    20341 gacctcgccg tcacgcccgg tgagaccgtc gccctgatgg gacgcaacgg cgcgggcaag
    20401 tccacgctcc tctccaccct ggtcggcctc ctcgaaccca cgtcgggcac ggtccgcgtc
    20461 ggcggcgccg ccccgcaccg cacggcgcca cgtcagctga tccggcacgt cggtctggtc
    20521 ccgcaggagc cgcgcgacct gttgtacgcg gacaccgtgg gcgccgagtg cgcctcggcc
    20581 gaccgggacg cggacgcggc gcccggggcg tgccgcgccc tggtgagcga gttgctgccg
    20641 ggcatcgcgg acgacacgca cccccgggac ctctccgagg gccagcgcct cgcgctcgcc
    20701 ctggcgatcg tcctgaccgc gcgcccgccc ctgctcctcc tcgacgagcc gacccgcggc
    20761 ctcgactacg cggccaaggc ccggctcgcc accgtgctgc gggggctcgc cgccgagggc
    20821 cacgcgatcg tgctcgccac gcacgacgtg gagctggccg ccgagatcgc ccaccgcgtg
    20881 gtgatcctcg cggacggcga gatcgtcgcg gacggcccga cgccggagat cgtcgtctcg
    20941 tcgccgtcct tcgcgccgca ggtcaccaag atcctcgcgc cgcacgagtg gctgaccgtg
    21001 tcgcaggtgc gccgggccct cggcgcggcc ggacaggacc cgtcgtgacg gccgcgccga
    21061 ccggccaggc gcaggcccgc cccatccgcc tgggccgccg ctcgatcgcc gcgctcgccc
    21121 tggtcaccgc cgtgggcgtg gccgccttcg gctggccgct cctcgccggt gccggttccg
    21181 gcctcagcga tcacgcgcag gacgcgccgt ggctgttcgc ggcgctgctc ccgctgctgc
    21241 tcgccgtggt ggtggcgacc atcgcggacg tcggcctcga cgcgaaggcc atcgcgatgc
    21301 tcggggtgct cgccgccgcg ggcgccgcgc tgcggccgct gggcgcgggg acggcgggca
    21361 tcgagccgat gttcttcctg atggtgctga gcggccgggt gctcgggccc ggcttcggat
    21421 tcgtcctcgg gtcggtgtcg atgttcgcct ccgcgctgct gaccggcggc gtcggcccgt
    21481 ggatgccctt ccagatgctg tcgatgggct gggtctgcat gggcgcgggg ctgctgccgg
    21541 gccccgacac cctgcgcggc cgccgcgaac tgtggctcct cgcggcgtac ggagcggtct
    21601 cctccgtcct gtacggcacg gtcatgaacc tgcagggctg gccctacctc gggggcctcg
    21661 ccaccggcgt ctccttcgtg cccggcgacc cgctcgccga caacctgggc cgtttcatcg
    21721 cgtactgcct ggccacctcg ctcggctggg acctgccgcg cgccgtcgtc acggtgctgc
    21781 tcagcctcac gctcgggccc gcggtcctga aggcgctgcg ccgggccacg cgccgggcgg
    21841 cgttcgaggc gccggtcaca ttcgaggccc ccaagccgta gggacgcctg cgcgttccgt
    21901 tacatcgggg cccctccgtg gtgaggcggc ccacaggact ttggtcctct acgaagaggg
    21961 ctcgtagtac gcgcaccttg atgtgcatgc gtcaatcacc gcgctgacct gggcattgag
    22021 agccacatca cacgatggac attcggcgcg ggtgcgactt ccactagtaa atggggtcat
    22081 tgcggcgggg taacagccct gcttctctgg aggagtcgca cggcgccgac gaacccaccc
    22141 gggtcgcggc gccgccgcat gtcccccccc cgggatcccc cacggatccc ccgcgatcca
    22201 cggcgtgcac ggcgacagcc ccgtccccca ccggaaggtc ctctgtgtcc gcctcgctca
    22261 tccgccgcat cgcttccccg aagaaggcca tcaccggcgg cctcgtcgcc gcagccgcca
    22321 ccggcatggt cttcgccgcg gccccggccc aggcagccac cccgaccacc gcgaaggccg
    22381 ccgtcccggc cgccgccccc gccgccgccc ccgcgtccgc ccaggccgtc gcgaagcaga
    22441 tgatcccgga cgccgcgcag taccaggcgt tcagcaacat cgtggcccac gagagcggct
    22501 ggaaccacac cgctaccaac tcctcctccg gcgcctacgg cctggtccag gcgctgcccg
    22561 gctcgaagat ggcctcggcc ggttcggact ggaagaccaa cccggcgacc cagatcaagt
    22621 ggggcctgga ctacatgaac tcccgctacg gcagcccggt cggcgcgtgg aacttctggc
    22681 aggccaacgg ctggtactga gccgccgcga gctgccactg agccaccgag aga
//
