LOCUS       NZ_CP022685            24451 bp    DNA     linear   CON 17-JAN-2024
DEFINITION  Streptomyces formicae strain KY5 chromosome, complete genome.
ACCESSION   NZ_CP022685
VERSION     NZ_CP022685.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces formicae
  ORGANISM  Streptomyces formicae
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Complete Genome Sequence of Streptomyces formicae KY5, the
            formicamycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9611874)
  AUTHORS   Holmes,N.A., Devine,R., Qin,Z., Seipke,R.F., Wilkinson,B. and
            Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2017) School of Biological Sciences, University of
            East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, United
            Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0; Newbler v. 2.3
            Assembly Name                     :: KY5 Genome
            Expected Final Version            :: yes
            Genome Coverage                   :: 56.0x
            Sequencing Technology             :: PacBio; 454; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/17/2024 10:10:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,274
            CDSs (total)                      :: 8,185
            Genes (coding)                    :: 8,082
            CDSs (with protein)               :: 8,082
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 39 of 103
            Pseudo Genes (incomplete)         :: 77 of 103
            Pseudo Genes (internal stop)      :: 11 of 103
            Pseudo Genes (multiple problems)  :: 22 of 103
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:13:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 117145
            Orig. end                         :: 141596
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP022685.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Matthew Hutchings,
            University of East Anglia, UK.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24451
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="3"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24451
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24451
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14451](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14451)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(252..267)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.45"
                     /tool="antismash"
     gene            complement(1527..2627)
                     /locus_tag="KY5_RS00510"
                     /old_locus_tag="KY5_0099c"
     CDS             complement(1527..2627)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (45-157). E-value:
                     5.1e-11. Score: 34.6. Matches aSDomain:
                     nrpspksdomains_KY5_RS00510_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="KY5_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0099c"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_098240272.1"
                     /sec_met_domain="PF00561 (E-value: 6.1e-08, bitscore: 31.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-07, bitscore:
                     31.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDGIARHTWEGVRDARVSTHPFTTADGLALNLTRFRRGEGEGDD
                     VVLLMHGLTASSDLFIMPEHYNMATYLLDHGFPDVWAVDLRISSRYPYNTEPGDSSLDD
                     VVHYDHPAMLAELRRHVGERRIHVVAHCMGSTALSMSLAAGTVTGITSMVAQSVGLVVK
                     VPGWSRWKIEFAPPLLEHVLGMSAIDPRMGNSARFTRSWALSKLVSLAHPECDNSACHL
                     VSLMWGAGWPALYSHANLEPETHDRIGDLLGPTGLHYYRHIRKMVRAGHAVKYATDDRR
                     HAALPDDYLAHAADISTPILFMTGQDNHVFGDSNVIGHQKLTQLAPDRHELAVLPGYGY
                     LDPIIGKRAHLDVFPRILDFLQRQAV"
     aSDomain        complement(2157..2492)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS00510_Abhydrolase_1.1"
                     /evalue="5.10E-11"
                     /label="KY5_RS00510_Abhydrolase_1.1"
                     /locus_tag="KY5_RS00510"
                     /protein_end="157"
                     /protein_start="45"
                     /score="34.6"
                     /tool="antismash"
                     /translation="VVLLMHGLTASSDLFIMPEHYNMATYLLDHGFPDVWAVDLRISSR
                     YPYNTEPGDSSLDDVVHYDHPAMLAELRRHVGERRIHVVAHCMGSTALSMSLAAGTVTG
                     ITSMVAQS"
     gene            complement(2841..3104)
                     /locus_tag="KY5_RS00515"
                     /old_locus_tag="KY5_0100c"
     CDS             complement(2841..3104)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987977.1"
                     /locus_tag="KY5_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0100c"
                     /product="hypothetical protein"
                     /protein_id="WP_098240273.1"
                     /transl_table=11
                     /translation="MEISGIFTAIVIGIVIGVLGRLVIPGRQRIGIGWTILVGIVAALV
                     GTGLAGALDVADTKGIDWIELAIQVGLAALGVVGVERLKGRR"
     gene            complement(3179..3790)
                     /locus_tag="KY5_RS00520"
                     /old_locus_tag="KY5_0101c"
     CDS             complement(3179..3790)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010636573.1"
                     /locus_tag="KY5_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0101c"
                     /product="DinB family protein"
                     /protein_id="WP_199842870.1"
                     /transl_table=11
                     /translation="MALDWNGLLVDQLDWHWQHQLRARLDGLTDDEYFWEPVPDCWTVR
                     PSGTGTAPVRAGSGGFTIDWAYPEPVPAPVTTIAWRLGHILVGVLGARSAAHFGGPPVD
                     YMTYAYPGTGAAALEQLDAAYARWIAGVRGLGDEGLARPCGEAEGAFAQEPMATLVLHI
                     HREMIHHGAEIALLRDLYAHRTSQGAAGVEGTGSPMPGNT"
     gene            3881..4111
                     /locus_tag="KY5_RS00525"
                     /old_locus_tag="KY5_0102"
     CDS             3881..4111
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566528.1"
                     /locus_tag="KY5_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0102"
                     /product="hypothetical protein"
                     /protein_id="WP_098240274.1"
                     /transl_table=11
                     /translation="MFNSRKVRAGDVWNGVVVDKTRSMPDGSNLYHYVEVRLDDGTSKK
                     ARIEKALWESLTTGDRLVKEEGTTAPTKAPQ"
     gene            complement(4124..5014)
                     /locus_tag="KY5_RS00530"
                     /old_locus_tag="KY5_0103c"
     CDS             complement(4124..5014)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645447.1"
                     /locus_tag="KY5_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0103c"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_098240275.1"
                     /transl_table=11
                     /translation="MHETSPTNPVAEAFESQRGRLLAVAHRMLGSHADAEDAVQEAWLR
                     LSRQDAAAIANLGGWLTTVVGRISLDVLRSRQARPEAPYDHRLPELVVTLDDGPAPEDD
                     AVLADSLGLALLVVLDSLGPNERLAFVLHDLFAVPFDEIGRILDKSTAAAKMLASRARK
                     KVRATERPTDAGRDQRKVVQAFLAAARSGDFQELLRVLDPDVRMSIDTPAGMVVTLGAT
                     KIAAGAQLAAGAASLGHAVFVNGLPGVISWHEDGTPLSLLAFTVRDGRITGITAVVDPA
                     KLALMDLPAPGAGRG"
     gene            5097..5546
                     /locus_tag="KY5_RS00535"
                     /old_locus_tag="KY5_0104"
     CDS             5097..5546
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852426.1"
                     /locus_tag="KY5_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0104"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_098240276.1"
                     /transl_table=11
                     /translation="MEARMKGTLDPDLGTAIQHIFKAIAAGGVDHRLLALVHLRASQIN
                     GCSPCVFASIDSAKKAGETEERLHNVVTWRDTPFFSDEERAALELTEAATRLQDGAAGV
                     TDEIWDAAADHFDEDQLSAIILEIATTNFFNRINRTIREQAGKTW"
     gene            complement(5624..6049)
                     /gene="arr"
                     /locus_tag="KY5_RS00540"
                     /old_locus_tag="KY5_0105c"
     CDS             complement(5624..6049)
                     /codon_start=1
                     /gene="arr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016473281.1"
                     /locus_tag="KY5_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0105c"
                     /product="NAD(+)--rifampin ADP-ribosyltransferase"
                     /protein_id="WP_098240277.1"
                     /transl_table=11
                     /translation="MSEPIRWGSEDPGPFFHGTKAEIAVGALLEPGYGSNYGKGSTANF
                     VYLTATLDAAVWGAELAAGDGRERIYLVEPTGSFEDDPNLTDKKFPGNPTRSYRTRQAL
                     RVLAEVRDWQGHSPEVLQHMRDHLEALKAQGIEAIND"
     gene            6156..7118
                     /locus_tag="KY5_RS00545"
                     /old_locus_tag="KY5_0106"
     CDS             6156..7118
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971303.1"
                     /locus_tag="KY5_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0106"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_098240278.1"
                     /sec_met_domain="APH (E-value: 1.3e-21, bitscore: 76.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRDEAADVRPLARAWVERHLDEGERIIGVEALHGGITAEVRRL
                     TIGSPDGATRDLVLRTFVDMTYEAAAEDWLNREALALTLLAGTGVPAPALVAVDPTAAH
                     CEYPALLKTHLAGRTTLDDEGLEARVPALAGQLVAIHALRPAERPKTYEALTTPDTVVT
                     PRGADAAAWAAAIEVIRRPAPPYEGRFLHRDFQPGNVLFDVLPEGAAGASVTGVIDWAG
                     ASWGPTDLDVAHCSTTLALLHGPAWGLRFADAYEKAGGVLAAASGERLYWQVRDALAAS
                     EEVALVARAWRESGRTELTTRAVEERLDAYVISVMDALG"
     gene            complement(7199..7771)
                     /locus_tag="KY5_RS00550"
                     /old_locus_tag="KY5_0107c"
     CDS             complement(7199..7771)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354319.1"
                     /locus_tag="KY5_RS00550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0107c"
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_098240279.1"
                     /transl_table=11
                     /translation="MTSDRRTLLADAALDVLADDGMRGLTHRAVDRKAAMPPGTTSAYF
                     RTRAALLTGLVTRLVQRDQAELHAMAEALPPLRTAEELVEGMAALTRKRLTGEGRRRSL
                     ARYACTVESVRDAELREILVPRDNPGREAVRLFLAAHGVTDVENRTHTLLTCIDGLVFD
                     GLVSGGEVRREALEGLVAAALRQAPGR"
     misc_feature    7826..7841
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            7856..9013
                     /locus_tag="KY5_RS00555"
                     /old_locus_tag="KY5_0108"
     CDS             7856..9013
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151945.1"
                     /locus_tag="KY5_RS00555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0108"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_098240280.1"
                     /transl_table=11
                     /translation="MGNTAVVVGGGIGGLAAAIGLDRVGWDVTVLERADVLEDAGAGIS
                     LAANGLRALDALGVGEAVREASRGQYTGGTRTPEGRWLARMDGSALEEAVGTPIMGIPR
                     ATLHRLLRDALPTASLVIGSEVDRVEEVVPGTVHVGCDTRVLDADLVVAADGIGSRVRG
                     RLFPDHPGPVHSGSTVLRALTEHVVDLRGDFELTWGRGAEFGHIALQDVRAEWHAVLNL
                     PAGTRFADPLAELRRRFRTWHEPIPALLDATRPQAVLHHDVNELRTPLPSFVVGRIALL
                     GDAAHAMTPHLGQGACQALEDAVTLAAALRAESTVDAALARYDAERRPRSQAVARAARQ
                     AGRMGQQLSHPLAVTLRNTAMRLTPSRLAIRMLLRHHAWTPPSLN"
     gene            complement(9021..9803)
                     /locus_tag="KY5_RS00560"
                     /old_locus_tag="KY5_0109c"
     CDS             complement(9021..9803)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471219.1"
                     /locus_tag="KY5_RS00560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0109c"
                     /product="hypothetical protein"
                     /protein_id="WP_098240281.1"
                     /transl_table=11
                     /translation="MTGVKTWRRCGTAAASIGLMLALSDPAAASVGGGNVSIGWSIPGT
                     PAGGLRDITFPLTVNQATAHKDGIYFAQQFGFTNASDVGYTGLQPRANSGGKERLSARF
                     STFVAGSTTTDPLCHTGADGGPGVTCAVDFDAVYGNRYDLKVERTGTDTWTGTARDTVT
                     GKETHLGSYTLPTGSGNLRGSQGGFVEYYAGIPSCAEMPRSDAVFGGPTTTEGGGLSGT
                     SRANYEYSDCVGESNYQAQNAGSGTHVTRGFVSGRAAD"
     gene            complement(10001..11296)
                     /locus_tag="KY5_RS00565"
                     /old_locus_tag="KY5_0110c"
     CDS             complement(10001..11296)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="KY5_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0110c"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_098240282.1"
                     /sec_met_domain="LANC_like (E-value: 5.7e-49, bitscore:
                     165.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENPVALLAERLTDPVALAAQVTEAQTPELAETRSLWHPQSLAD
                     GHAGVALLLGALAHTDAGYARAAHAHLTSAVTGVRRPAREGLYAGLPAVAFAARTAVTR
                     PGEYAGLLTKLDDQVALLARRIVAEDAPRVAAGTAGARMAGYDVVAGLTGLGRLLLAAG
                     PDHRDTTELVLGHLVALTRPVVEPGGRTVPGWWTSDPILLSEPEGVPGGHFNAGLAHGI
                     PGPLALLSLAHRAGVRVPGQERAIRTIADWLLARRSPDGAGWPNIVPLGAELTAASGAR
                     PDLAEARTGWCYGTPGVARSLQLAALALKEPEWNRQAVAAVAAACDRRDFPDPTLCHGL
                     AGLTTIVTLMSKEPGGDELAALVPRLTDALAAAADPGYPFLWPAAAPGERTVVHRPGFL
                     DGAVGAALALRHATHPEAPLGELPWQAALLLC"
     gene            complement(11293..14451)
                     /locus_tag="KY5_RS00570"
                     /old_locus_tag="KY5_0111c"
     CDS             complement(11293..14451)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="KY5_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0111c"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_159072447.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.3e-174,
                     bitscore: 579.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.8e-17,
                     bitscore: 62.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.7e-34, bitscore:
                     116.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQVQSAETVFHCADGVLLRAPLLARPRARATWQDGVRESQDGTG
                     AESPDSTDLEGRRAQLEELLADARFREAVEVSSPSLARTVDAVLANAPVTPADLRKAHR
                     AVTRYLLRAASRPTPFGLLAGVLWGSFGAATKGELTGEGHKAARLDAGLLARLVAEWER
                     DPAVHQGLSVVVNGLCFVRGGRLVLPFAPAGPGPDTASSDASRPKSRTLRHTPVVRAVL
                     EAAARPVRCDELVRDVEARFPGAPEGAVARLVAQLIGAEVLLTELRPPLDAPDPLAHVE
                     ALLPADTPAARRIAELRTSLTDYLRTPLGEGRAAWRTALGAATGATEDAPASGHAVQVD
                     LRLDGSVVLSHEVARELEHAAAALWRLAPQGRGRLTAYHQDFVERYGLGRYVPVKELLD
                     PDIGLGAPAGYRLPPSHRSDPGPAPLGAVRQRLLLGLAAEAQARGSREVVLDEQWLRKL
                     ESADRAESADRDAPAVRPPALELVVQIAATSADAVDRGDYTLVLNGAATASGGLMGRFA
                     HLFEPAQAEAIRHTVRDAREDTGRLPVQVHHQASHHRHANVAQVPTWLDGRLVIGVHPG
                     PAAPGVTDLTLDDIAVCADSEGFRIVSLALGRELTPSALHVLNRELTAPNAVRFLIEAA
                     AFSRRQWRLWEWGAAEDLPFLPAVRVGRTVLAPARWRLEATGPSLAEWRALWHVPDHVQ
                     LTLGDHRIPLNLSVPAHQEILRRECERTGAAVVHEPPLGQDPDSGWLHGPGGAHEAEAV
                     VTLTPRQRNAEPRPAKPARIALPASRRGTGEIPPGGPWLYATLYTSAERQDELLTGPLR
                     RFLTELPAPQDEPGGVDRWFFIRYADPDPHLRLRLHGDPALLNGVVLPGLHDLAGELAA
                     DGLARGLRLDSYAPETERYGGPVVLGAAEEVFHADSRLVIERLATPTDDRILSTAYDVA
                     GLVRAFHRGYGGDWRQWITTTYPKREKHHKAFAARRREALARITPDGPEAHAHHAAPER
                     FGHLMREEQRRGTLSVSPDAVLASLVHMHCNRRLGTDRTAEAQALAVARGAVQAHLDRE
                     RAGS"
     aSDomain        complement(13642..13935)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KY5_RS00570_Lanthipeptide_LanB_RRE.1"
                     /evalue="6.30E-20"
                     /identifier="RREFam001.1"
                     /label="KY5_RS00570"
                     /locus_tag="KY5_RS00570"
                     /protein_end="270"
                     /protein_start="172"
                     /score="62.7"
                     /tool="antismash"
                     /translation="VVVNGLCFVRGGRLVLPFAPAGPGPDTASSDASRPKSRTLRHTPV
                     VRAVLEAAARPVRCDELVRDVEARFPGAPEGAVARLVAQLIGAEVLLTELRPP"
     misc_feature    complement(14417..14431)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.2"
                     /tool="antismash"
     gene            14655..14798
                     /locus_tag="KY5_RS41670"
                     /old_locus_tag="KY5_0112"
     CDS             14655..14798
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KY5_RS41670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KY5_0112"
                     /product="hypothetical protein"
                     /protein_id="WP_157877684.1"
                     /transl_table=11
                     /translation="MPESMTQDLFDIDLTETSIQDVAQDSAAGAISGEESCFRTCTTCS
                     LC"
     CDS_motif       14655..14732
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPESMTQDLFDIDLTETSIQDVAQDS"
                     /locus_tag="KY5_RS41670_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14733..14798
                     /prepeptide="core"
                     /locus_tag="KY5_RS41670_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="3.70"
                     /molecular_weight="2002.2"
                     /monoisotopic_mass="2000.9"
                     /core_sequence="AAGAISGEESCFRTCTTCSLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPESMTQDLFDIDLTETSIQDVAQDS"
                     /leader_location="[14654:14732](+)"
                     /alternative_weights="2020.3"
                     /alternative_weights="2038.3"
     gene            complement(15097..16053)
                     /locus_tag="KY5_RS00575"
                     /old_locus_tag="KY5_0113c"
     CDS             complement(15097..16053)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (54-167). E-value:
                     2.9e-15. Score: 48.5. Matches aSDomain:
                     nrpspksdomains_KY5_RS00575_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538152.1"
                     /locus_tag="KY5_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0113c"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_098240284.1"
                     /sec_met_domain="PF00561 (E-value: 6.4e-12, bitscore: 44.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.1e-07, bitscore:
                     29.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPTTPTTPTTPTTPTTPTTPTTPPTGTASAAPTTGTLRVPGAT
                     LHYEVRGEGPLLLLIPGGAGGAAAFDDLADGLAAEYTVATYDPRGISRSALDDPEAAQR
                     VAEHADDAFRLLELLSPGEPARVFGMSSGAIAALHLLTTHPERVERLVAHEPPVVEVLP
                     DAAEHRALLARVQETFRTQGLMPAVSVFAEGAKRKGDAGNDDAGKGAPAAPKPELTLPP
                     QAAARAERTMANLPYFFGRVIPSFMAYAPDVARLQELADRVVFAGGQDSHGELPYRPAA
                     FLAERCGTELRHFPGGHTGLTTHPDEFGELLRQVFRA"
     aSDomain        complement(15553..15891)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS00575_Abhydrolase_1.1"
                     /evalue="2.90E-15"
                     /label="KY5_RS00575_Abhydrolase_1.1"
                     /locus_tag="KY5_RS00575"
                     /protein_end="167"
                     /protein_start="54"
                     /score="48.5"
                     /tool="antismash"
                     /translation="PLLLLIPGGAGGAAAFDDLADGLAAEYTVATYDPRGISRSALDDP
                     EAAQRVAEHADDAFRLLELLSPGEPARVFGMSSGAIAALHLLTTHPERVERLVAHEPPV
                     VEVLPDAAE"
     gene            complement(16050..16643)
                     /locus_tag="KY5_RS00580"
                     /old_locus_tag="KY5_0114c"
     CDS             complement(16050..16643)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538151.1"
                     /locus_tag="KY5_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0114c"
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_098240285.1"
                     /transl_table=11
                     /translation="MVRAGLTAERVTVAGAELADEVGFEQVTMSRVARRLGVKDASLYT
                     HVRNLVDLRGRIALLAADEKTIRIAEATVGLAGKDALVAFATAWREYAHEHPGRYTATQ
                     TPIDIDPELAAHAPGPRRAVELTYGMLRGYGLAEPDLTDAVRLLRSTFHGFVALEAMGG
                     FAHQRAPQQSWVRALDALHALLEHWPPLGDGESA"
     gene            16901..17641
                     /locus_tag="KY5_RS00585"
                     /old_locus_tag="KY5_0115"
     CDS             16901..17641
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (36-138). E-value: 3.4e-10. Score:
                     30.5. Matches aSDomain: nrpspksdomains_KY5_RS00585_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152071.1"
                     /locus_tag="KY5_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0115"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_098240286.1"
                     /transl_table=11
                     /translation="MSAQQYDEIGEAYEGFKALPLEQYSVVPGFLALVGDVRGKSVLDL
                     ACGTGFYSREFKRRGATELLGIDISGEMVAVAQALEERDPLGVRYEVGDASELRAFDER
                     FDVGLAVQLLNYAEDIATTERMCRNVHRSLKPGGEFFLLNQSPDFDFDGPTPEKYGFRS
                     VLTGEQVETGPKVRTTALLDPPVSFVANLPRREVYETCLRAAGFSELTWVPLTVSEAGV
                     REFGADHWADYHANPPLEMLRCRV"
     aSDomain        17009..17314
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KY5_RS00585_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.40E-10"
                     /label="KY5_RS00585_oMT.1"
                     /locus_tag="KY5_RS00585"
                     /protein_end="138"
                     /protein_start="36"
                     /score="30.5"
                     /tool="antismash"
                     /translation="VRGKSVLDLACGTGFYSREFKRRGATELLGIDISGEMVAVAQALE
                     ERDPLGVRYEVGDASELRAFDERFDVGLAVQLLNYAEDIATTERMCRNVHRSLKPGG"
     gene            complement(17670..18818)
                     /locus_tag="KY5_RS00590"
                     /old_locus_tag="KY5_0116c"
     CDS             complement(17670..18818)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669339.1"
                     /locus_tag="KY5_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0116c"
                     /product="DUF6596 domain-containing protein"
                     /protein_id="WP_098246982.1"
                     /transl_table=11
                     /translation="MNETLLRSLTPSVLAVLVRRGADFAAAEDAVQDALVEAVRVWPAD
                     PPRDPKGWLVTVAWRRFLDARRADTARRRREDLIEEEPAPGPAPAVDDTLQLYFLCAHP
                     SLTPSSAVALTLRAVGGLTTRQIARAYLVPEATMAQRISRAKRTVSGVRLDRHGDVATV
                     LRVLYLVFNEGYSTDADVDLTAEAIRLTRQLAAVIDHPEVVGLLALMLLHHARRAARTG
                     PDSALVPLAEQDRGRWDTELITEGIGILQTALARDRLGEFQAQAAIAALHADAQRAEET
                     DWVQIVEWYDELVRLTGSPVVRLNRAVAVGEADGARAGLAELAELDDTLPRHTAVAAYL
                     HERDGDLGTAARLYADAAGKAANLAERDHLTRQAARLNARRQ"
     gene            complement(18839..19246)
                     /locus_tag="KY5_RS00595"
                     /old_locus_tag="KY5_0117c"
     CDS             complement(18839..19246)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003935476.1"
                     /locus_tag="KY5_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0117c"
                     /product="YciI family protein"
                     /protein_id="WP_098240287.1"
                     /transl_table=11
                     /translation="MAKYLLLKHYRGAPASVNDVPMDQWTPEEVSDHMRYMNDFADRLK
                     ETGEFVDSQALAPGGSFVRYDGEGRPPVTDGPFAETKDLIAGWMIIDVDSQERAVELAG
                     ELSAAPGAGGKPIHEWLEVRPFMGAKPTITE"
     misc_feature    19337..19351
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.81"
                     /tool="antismash"
     misc_feature    complement(19413..19428)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.66"
                     /tool="antismash"
     gene            complement(19511..20689)
                     /locus_tag="KY5_RS00600"
                     /old_locus_tag="KY5_0118c"
     CDS             complement(19511..20689)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010037287.1"
                     /locus_tag="KY5_RS00600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0118c"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_234362563.1"
                     /transl_table=11
                     /translation="MSTSDPPSGLVDFLADRDNAVLDLSTAVARCASALGVPEATVYLV
                     DLQQRLLVPLDESAAAVAVDGSAAGWAYRTLSLRAGESATGGMTAWLPLLDGAERLGVL
                     AVHAPYLDAALLRRGRALAALAAMMITSKRAYKDNVVQCTRAEPMRLPAEMLRAFLPPR
                     TIGNHHVISTAVLEPAYEIGGDAFDHCLTRTALHATIVDAMGHNLLSGLTTAVALAACR
                     NGRRTGSDLPELMEAVDAALGQWLPDQFCTGVLLRLDLASGALRWSNCGHPAPLLIRGN
                     RLVEGALEREPDSPMGFSASFRSAERQVHETALEPGDRVLLYTDGLTEARLADGTEFGL
                     ERFADSVIRASTAGEVAPETLRRLIHSVLDTQSQSLRDDATILMIEWQPPGR"
     gene            20868..21182
                     /locus_tag="KY5_RS00605"
                     /old_locus_tag="KY5_0119"
     CDS             20868..21182
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983453.1"
                     /locus_tag="KY5_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0119"
                     /product="hypothetical protein"
                     /protein_id="WP_098240289.1"
                     /transl_table=11
                     /translation="MSEQVPASPGADGSTPVPRDLPDQQADGGQDPWELAEDGKDAKSG
                     RTGAAEDGDGGAADDVPDTDEAGTGRRGESGGDQGGRDAEDGHDASAPTDNPEPEEPSG
                     "
     gene            21229..21600
                     /locus_tag="KY5_RS00610"
                     /old_locus_tag="KY5_0120"
     CDS             21229..21600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009995202.1"
                     /locus_tag="KY5_RS00610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0120"
                     /product="hypothetical protein"
                     /protein_id="WP_098240290.1"
                     /transl_table=11
                     /translation="MSGTGDAPAQVSVELSGGADDAGSVFALLGAAFASDRADGPAPRA
                     AESGGPTVWSGVFDTARPAGGGPSGSPSLSGPVTASVQGGYVAVDRVVTVLSAAFTVTE
                     EGSASGDQEKDVNLRLEGA"
     gene            complement(21675..22220)
                     /locus_tag="KY5_RS00615"
                     /old_locus_tag="KY5_0121c"
     CDS             complement(21675..22220)
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607049.1"
                     /locus_tag="KY5_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0121c"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_098240291.1"
                     /transl_table=11
                     /translation="MAEFLTDIKTIRERARQQIEKGPVTDAYGADLERVLGVLNEALAT
                     EIVCTLRYKRHYYTASGLYSEPVAAEFLEHAQEEQEHADKLAQRIVQLGGEPDFNPDTL
                     TSRAHAEYDASTDLIEMIKEDLVAERVAVAAYTEIAKWLGDGDPTTRRVFEELLAQEEE
                     HADDLRGLLERIPGGQRG"
     misc_feature    complement(22195..22208)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            22499..23896
                     /locus_tag="KY5_RS00620"
                     /old_locus_tag="KY5_0122"
     CDS             22499..23896
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010046630.1"
                     /locus_tag="KY5_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KY5_0122"
                     /product="amino acid permease"
                     /protein_id="WP_098240292.1"
                     /transl_table=11
                     /translation="MPSSTSTPPKPALTPEPQLAKGLKQRHLSMIALGGVIGAGLFVGS
                     GAGIAAAGPSIVLAYTASGLLVMLVMRMLGEMSAAHPASGSFSVHAERAIGPWAGFTSG
                     WSFWFMLCMGVGLEGIGAAHIMTGWLPGTPEWAWVALFMAVFCGANLAAVKNFGEFEFW
                     FAALKVGAIVLFLAVGGLAIAGVLPGTDAPGTANLVGHGGFLPNGTEGLIIGLLASVLA
                     YGGLETVTIAAAESDDPVRGVAGAVRTAMWRIAVFYIGSMLVIVALVPWDDKEVVEKGP
                     YVAALDQLGIPGAGQIMNVVVLIALLSAMNANIYGSSRMACSLVSRGQGPAALGRTVSG
                     VPRRSVIASSAFGFLCVLLSYWRPDDIFQWLLNMIGAVILVVWTFTAVSQLILRRRTEQ
                     EEPGKLAVRMWAYPYLTWVALAGMAAVFVLMALEPTTRGQLAWTSGLTLALVIAGYVRQ
                     RTARGRR"
ORIGIN
        1 cgcgcttgag cagccagtga gggctgtccg cgtaccgtcc gcccagggcc tcggacacgg
       61 cgcgcagggc cgcgcgcacc cgtgcgtagt gctgggcgct gcctgcggtg gaccactcgg
      121 cgtccagggt gccgcgccgc agtaccagta ccccgtccgg cgtgtcccgg cccatgccga
      181 gcagcggcag ggaggtgtcc gacaggacgc cgtcgtcgag gaggcccgtc agcgaggcgg
      241 ccgtggcgtc cgggtcgccc acggcgtgcg cggcgagttg ccggagcagg aagcgtccgg
      301 cccgccccgc gtcacggggc agcgcggccg cctcgaccag ccagccgacg aaggccgggt
      361 aacccccgtc ctggaggtag ccgcccctgc ccggtggcac gcatccggag tggtcctgcc
      421 cgtcgaggtc gtcgggcagc cggatggtgc tggtgatgac cgggcctcgg ctcggggcca
      481 cgctggaggg gcgggcgtcg tgagcgtcct tggtgcggac ggcgaacgac aggatgtctc
      541 cgttgccgga gaagcgcgtt ccgagcgccg ctccgatccc cgggaggtgt cggcggctgc
      601 gcagcaggag gccggaggtg ccgtaggtac cggcggcgag gaccaggcga tcgcagtgga
      661 gggtgcggac cgggacacag tcggcgggcg ggccgtccgg agcggggtcg cgtcgcaggt
      721 agtcgacctc gtacccgccg cgcgcggagg ggcggatcgt gcgtacctcg tgccccgtgc
      781 gcagatcggc gccgtgtcct cgcgcggccg agaggtaggt gaagtcgagg ctgttcttgg
      841 ctccctcgtt gcagccgatg ttgcactccc cgcagagtcg acacgtccgg cgggtggccc
      901 cgtgcaggtt tccgtggtcc ggttcgacga tcggcaggcc gatgccgggc cgagcgccgg
      961 gctcgggcgc gaagctgacg gcgaggggcg ggaggaagtg ttcgaggccg agccggtcgg
     1021 cggcggtgcg catcgcgcgg gccttgggga cgtcgtcgta tccagggtgc tccagcgggt
     1081 agggcgtggg gttcagcacg cgctcgaccg catcgtagtg ggggtcgagg tccgcgcggg
     1141 tcaccggcca ggactcgtag ccgccgccag gcagttgctg ccgttcgacg aaccagtgct
     1201 cgtccttgcg cagcagtacg ttggcgtaga tgagcgaacc gccgccgagg ccgctggcga
     1261 cgaccgagtc gaagtggcgg aagctccaca cgtcgaacag gccgtacgaa ccggtctcgg
     1321 gcgcccagaa cgcgcgcgcc gcctgagcgg gtgtgcgggc gaagctgccc ggcgggtagt
     1381 ccctgccgcg ttccatcacc accacaccga gccctgcctg cgccaggcgc tcggcggcga
     1441 ccgagccgcc gaaccccgaa ccgacgacca ggacgtcgac gtgttcggtc gcggtgtgtt
     1501 ctgtcgcggt cccgtccctg cccatgtcag accgcctgcc gctggaggaa gtccaggatc
     1561 cgcgggaaga cgtccaggtg tgccctcttg ccgatgatcg ggtcgaggta tccgtagccg
     1621 ggcaggaccg ccaactcgtg ccgatccggg gcgagttgcg tgagcttctg gtgaccgatg
     1681 acgttggagt cgccgaagac gtggttgtcc tgccccgtca tgaagaggat cggggtgctg
     1741 atgtcggccg cgtgcgcgag gtagtcgtcg ggcagcgccg cgtggcggcg atcgtcggtg
     1801 gcgtacttga ccgcgtgtcc ggcccgcacc atcttgcgga tgtgccggta gtagtgcagg
     1861 ccggtggggc cgaggaggtc gccgatccgg tcgtgggtct ccggctccag gttggcgtgg
     1921 ctgtagaggg cgggccaacc ggctccccac atcaggctca cgaggtggca cgcggagttg
     1981 tcacactccg ggtgcgcgag agacacgagt ttcgacagcg cccaggaacg tgtgaagcga
     2041 gccgagttcc ccatcctggg atcgatggcc gacatcccca acacgtgttc cagcagcggc
     2101 ggggcgaatt cgatcttcca ccgggaccag cccggcacct tgacgaccag gcccacgctc
     2161 tgcgcgacca tgctggtgat ccccgtgacc gtgcccgcgg ccaggctcat cgacaacgcc
     2221 gtggagccca tgcagtgggc gacgacgtgg atgcgccgct ctcctacgtg ccgacgcagt
     2281 tcggccagca tggccggatg gtcgtagtgg acgacgtcgt ccagcgagga gtccccgggt
     2341 tcggtgttgt acgggtaccg gctgctgatg cgcaggtcga ccgcccacac gtcggggaaa
     2401 ccgtggtcca ggaggtaggt cgccatgttg tagtgctcgg gcatgatgaa caggtcgctc
     2461 gacgcggtca ggccgtgcat caggagcacg acgtcgtcgc cctcgccctc gccccgccga
     2521 aagcgggtca ggttcagggc gagaccgtcc gcggtggtga acgggtgtgt cgaaacccgc
     2581 gcgtcacgca ccccctccca cgtgtgccgc gcaataccgt cccgcatggc tcatcccccc
     2641 gtctccgcgt tgcgccgtcc tcgcgatccc gtgtcttcgc gtcgcaccgc ggcggagtgg
     2701 aaacggtaga cgcactgatc aagtacgcac aaccgacggg gggttgacct gccactggac
     2761 ccaggactgt agtgagatga cggttcccac cagtgaggta cgaggtgtac cgcgctggta
     2821 tgaggcccgc cgccatcacc tcatcggcgg cccttgagcc gctccacacc cacgacaccg
     2881 agtgcggcga ggccgacctg gatggccagt tcgatccagt cgatgccctt ggtgtcggcg
     2941 acgtccaagg caccggcgag gcccgttccg acgagtgccg cgacgatgcc gaccaggatc
     3001 gtccagccga tgccgatgcg ctggcggccg gggatgacca ggcggcccag gacgccgatc
     3061 acgatgccga tcacgatcgc ggtgaagatg ccggagatct ccatgccttc tcgcctttcg
     3121 tcgctcggga acttcgacac agccgcgtcg attcagcagc ttcgacacgg ctgtcgattc
     3181 acgtgttccc tggcatcggg gacccagtcc cctcgacgcc ggccgcgccc tggctcgtcc
     3241 ggtgcgcgta caggtccctg agcagagcga tctccgctcc gtggtggatc atctcgcggt
     3301 ggatgtgcag cacgagcgtc gccatcggct cctgcgcgaa cgctccctcg gcctcgccgc
     3361 acggccgtgc caagccctca tcgccgagcc cccgtacccc ggcgatccat cgtgcgtacg
     3421 ccgcgtcgag ctgctccagc gccgccgccc ctgtccccgg atacgcgtac gtcatgtagt
     3481 ccacgggcgg cccgccgaag tgtgcggcgc tgcgcgcgcc caggacgccg acgaggatgt
     3541 gcccgaggcg ccaggcgatc gtcgtgaccg gcgcgggaac cggttccgga taggcccagt
     3601 cgatcgtgaa gcctccggat cctgcccgca ccggggccgt gccggtgccg ctcgggcgca
     3661 cggtccagca gtccggtacg ggttcccaga agtattcgtc gtcggtgagg ccgtcaaggc
     3721 gcgcgcgcag ctggtgctgc cagtgccagt cgagctggtc gacgaggagt ccgttccagt
     3781 ccagtgccat gggctccacg ctaggacggg ggcgctcggc gcgctcctcg gcggcgcgtg
     3841 ccggaatcgg gccgatggcc agggccgata ctctggcgac atgttcaact ctcgcaaagt
     3901 acgagcaggg gacgtctgga acggcgtcgt cgtcgacaag acccgctcga tgcccgacgg
     3961 ctccaacctc taccactacg tcgaggtccg cctcgacgac ggcacgtcca agaaggcccg
     4021 tatcgagaag gccctgtggg agtcgctgac gacgggtgac cgtctcgtca aggaggaggg
     4081 cacgacggct ccgaccaagg cgcctcagta gacgccacac ccgtcatccc ctccccgctc
     4141 caggagccgg aaggtccatc agcgcgagct tcgccggatc gaccacggcc gtgatgccgg
     4201 tgatccggcc gtccctgacg gtgaacgcga gaagggagag cggggtgccg tcctcgtgcc
     4261 aggagatgac ccccggcagc ccgttgacga acaccgcgtg acccagcgag gcggcgcccg
     4321 cggccaactg cgcgcctgcg gcgatcttgg tggctccgag ggtgacgacc atcccggcgg
     4381 gagtgtcgat gctcatgcgt acgtcggggt cgagcacccg cagcaactcc tggaagtcgc
     4441 cgctgcgagc cgccgccaag aaggcctgaa ccaccttgcg ctggtcccgt cccgcatccg
     4501 tcggccgctc ggtcgcgcgc accttcttgc gagcgcgact ggcgagcatc ttggcagcgg
     4561 cggtcgactt gtcgaggatc ctgccgatct cgtcgaacgg gaccgcgaac aggtcgtgga
     4621 gcacgaacgc cagccgctcg ttcggtccga gcgagtcgag tacgacgagc agcgcgagcc
     4681 ccagggagtc ggcgagcacc gcgtcgtcct cgggagccgg accgtcgtcg agcgtcacga
     4741 cgagctcggg cagccgatgg tcgtagggcg cttcgggacg ggcctggcgc gatcgcagga
     4801 cgtcgagact gatccgcccc accaccgtgg tcagccagcc cccgaggttg gcgatggccg
     4861 ccgcgtcctg gcgggacaga cgcagccacg cctcctggac cgcgtcctcg gcatcggcgt
     4921 gtgagccgag catgcggtgg gcgaccgcga gcagtcggcc gcgctgggat tcgaacgcct
     4981 cggccaccgg attcgtcggg ctggtctcgt gcatgttgtt accttcctcg gcatcgctcc
     5041 gtcatgggga tgacgagccc gaaagggcac aggtaaccga tgaaggagcg aagccgatgg
     5101 aagcacgtat gaagggcacg ttggaccccg atctgggcac cgcgatccag cacatcttca
     5161 aggcgatagc cgccgggggc gtcgaccacc gcctgctggc ccttgtccac ctgcgggcca
     5221 gccagatcaa cggctgcagc ccgtgcgtct tcgcctcgat cgactcggcg aagaaggccg
     5281 gtgagacgga ggagcggctg cacaacgtgg tgacgtggcg cgatacgccc ttcttctccg
     5341 acgaggagcg ggccgcgctg gagctgaccg aggccgccac ccggctccag gacggtgcgg
     5401 cgggggtgac cgacgagatc tgggacgccg cggccgacca cttcgacgag gatcagctct
     5461 cggcgatcat cctggagatc gcgacgacca acttcttcaa ccggatcaac cgcacgatca
     5521 gggaacaggc cggcaagacc tggtgagttg acgcgggcgc cgtccgggcc gggtgcatgc
     5581 gtgcggccgg cccggagggg ctccgggggg cggggcggcc tgatcagtcg ttgatggcct
     5641 cgatgccctg ggccttgagc gcttcgaggt gatcccgcat gtgctggaga acctcgggcg
     5701 aatgcccttg ccagtctctg acctcggcga ggacgcgcag tgcctggcgc gtgcgatagg
     5761 accgggtcgg gttgccgggg aacttcttgt ccgtcagatt cgggtcgtcc tcgaaggagc
     5821 cggtgggctc gacgaggtag atccgctcgc gcccgtcacc ggccgcgagt tcggctcccc
     5881 agacggcggc gtccagcgtg gccgtcaggt agacgaagtt cgccgtactg cccttgccgt
     5941 agttggagcc gtagcccggc tccaggaggg ccccgacggc gatctccgcc ttcgtgccgt
     6001 ggaagaaggg accggggtct tcgctgcccc accggatcgg ctcgctcaca tgcgcccctt
     6061 gaacgttgat ggtccggcaa cggtaactcg gtggatcatt ccggagaacg gtgacagcct
     6121 cgttggcgcg ccgggaagag ggatgaggtg gcacggtgac cgaccgcgat gaggccgcgg
     6181 atgtccggcc gttggcacgg gcctgggtgg aacggcatct ggacgagggt gaacggatca
     6241 tcggggtcga ggccctgcac ggcggcatca ccgccgaagt gcggcggctg accatcggtt
     6301 cgccggacgg cgccactcgc gacctggtcc tgcggacctt cgtcgacatg acctacgagg
     6361 cggccgccga ggactggctg aacagggagg ccctcgccct gaccctgctc gcggggaccg
     6421 gcgtaccggc ccccgcgctg gtcgcggttg atccgaccgc cgcgcactgc gagtatccgg
     6481 cgctcctcaa gacacatctg gcgggccgga cgaccctcga cgacgaaggg ctggaggcgc
     6541 gcgtccccgc gctggccggt caactcgtgg cgatccacgc gttgcgcccc gccgaacggc
     6601 ccaagacgta cgaggcgttg acgacccccg acaccgtcgt gactccgcgg ggcgccgacg
     6661 cggcggcgtg ggccgcggcg atcgaggtga tacgcaggcc cgcgccgccc tacgaggggc
     6721 gcttcctgca tcgggacttc cagcccggca acgtgctgtt cgacgtgctg cccgaggggg
     6781 cggcgggcgc gtccgtcact ggcgtcatcg actgggcggg cgcctcttgg ggccccaccg
     6841 atctcgatgt ggcgcactgc tccaccactc tcgcgctgct gcacggcccg gcatggggcc
     6901 tgcggttcgc cgatgcgtac gagaaggccg gcggggtgct ggcggcggcc tcgggcgagc
     6961 ggctgtactg gcaggtgcgg gacgcgctcg ccgcttcgga agaagtggcg ttggtggcgc
     7021 gggcgtggcg tgagtcgggg aggacggagc tgacgacgcg ggccgtggag gagcggctcg
     7081 acgcgtatgt catctccgtg atggatgcgc tgggctgagc cgagcggccc cgggcgcgac
     7141 gggcgggaag tgacggcaca cggcggaccg gtggttccag caggggccta ggtcgccact
     7201 acctgccagg tgcctggcgc agcgccgcgg cgaccagccc ttcgagggcc tcgcgccgta
     7261 cttcgccgcc gctcaccagc ccgtcgaaga ccagtccgtc gatgcaggtc agcaacgtgt
     7321 gcgtgcggtt ctcgacgtcc gtgacgccgt gcgcggcgag aaagagccgg acggcctcgc
     7381 ggccggggtt gtcccggggc acgaggatct cgcgcagctc cgcgtcgcgc acgctctcga
     7441 cggtgcaggc atagcgggcg agcgagcggc ggcggccctc gccggtgagt cgcttccggg
     7501 tgagcgccgc catgccctcc accaactcct cggcggtacg caggggtggg agcgcttcgg
     7561 ccatcgcgtg aagttccgcc tggtcgcgtt ggacgaggcg ggtgacgagt ccggtcagca
     7621 gggccgcgcg ggtgcggaag taggccgagg tggtgccggg cggcatggcg gccttccggt
     7681 cgacggcgcg gtgggtcagg ccgcgcatgc cgtcgtcggc gagtacgtcg agggccgcgt
     7741 ctgccagcag ggtgcgccga tccgaggtca tggcaccttt ctacacccgc cttctacacc
     7801 cgtagaagca cggggtaagg tccctttcta cagatgtaga aggaggggca tcggcatggg
     7861 gaacacggca gtggtggtcg gcggaggcat cggcggactg gccgccgcga tcggcctgga
     7921 ccgcgtcgga tgggacgtga cggtccttga acgcgcggac gtgctcgagg acgcgggcgc
     7981 gggcatctcc ctggccgcca acggtctgcg ggccctggac gcactcggcg tcggcgaggc
     8041 ggttcgggag gcgtcgcggg gccagtacac cggtggcacc cggacgcccg agggcaggtg
     8101 gctggcgcgg atggacggct cggcgctgga agaggcggtg ggcacaccga tcatgggcat
     8161 cccccgcgcc acgttgcacc gactgctccg cgacgcgctg cccaccgcgt cactggtgat
     8221 cggatccgag gtggaccggg tcgaggaggt cgtcccgggg accgtccacg tcggctgcga
     8281 caccagggtc ctcgacgccg atctggtggt ggcggccgac ggcatcggca gcagagtccg
     8341 cggccgcctc ttcccggacc accccggccc tgtgcacagc ggctcgacgg tgctgcgcgc
     8401 cctcaccgag cacgtcgtcg acctgcgcgg cgacttcgaa ctgacctggg gccgtggcgc
     8461 ggagttcgga cacatcgccc tccaggacgt gagggccgag tggcatgccg tcctcaacct
     8521 ccccgccggt acgcggttcg ccgacccgct ggccgagctg cgccgacggt tccgcacctg
     8581 gcacgagccg atccccgccc tgctcgacgc gacccggccg caggccgtgc tgcatcacga
     8641 cgtgaacgaa ctccggacgc ccctgccttc cttcgtggtc ggccggatcg cgttgctcgg
     8701 cgacgcggcc cacgcgatga ccccccatct cgggcagggt gcctgccagg ccctggagga
     8761 cgcggtcacc ctggccgccg ccctccgcgc cgaatccacc gtcgacgccg cgctcgcccg
     8821 ctacgacgcc gaacgccgac cgcgcagtca ggccgtcgca cgggccgccc ggcaggccgg
     8881 gaggatgggc cagcagctct cccatcccct ggcggtcacc ctgcggaaca cggcgatgcg
     8941 gctcacgccc tcccgcctcg ccatacgtat gctcctccgt caccacgcct ggacgccacc
     9001 gtcgctgaac tgatccggtc tcagtcggcg gccctgcccg agacgaagcc gcgggtgacg
     9061 tgtgtgcccg atccggcgtt ctgggcctgg tagttggact cgccgacgca gtcgctgtac
     9121 tcgtagttgg cccgggacgt gccgctcagg ccgccccctt cggtggtggt ggggccgccg
     9181 aagacggcgt cggacctggg catctcggcg cagctgggga ttcccgcgta gtactcgacg
     9241 aaaccgccct gggagccccg gaggttgccg ctgcccgtcg gcagcgtgta gctgccgagg
     9301 tgggtttcct tgccggtgac cgtatccctg gccgtgccgg tccaggtgtc ggttcccgtg
     9361 cgctcgacct tgaggtcgta ccggttgccg tacacggcgt cgaagtcgac cgcgcaggtg
     9421 acgccggggc caccgtcggc tcccgtgtgg cagagcgggt cggtggtggt cgagcccgcg
     9481 acgaaggtgg agaagcgggc ggagagtcgc tctttcccgc cgctgttcgc gcgcggctgc
     9541 aggcccgtgt atccgacgtc cgacgcgttc gtgaagccga actgctgggc gaagtagatg
     9601 ccgtccttgt gggccgtggc ctggttgacg gtgaggggga aggtgatgtc gcgcaggccc
     9661 ccggcggggg tgccggggat cgaccagccg atcgacacgt tcccgccgcc gaccgaagcg
     9721 gccgcggggt cggacagcgc cagcatcagc ccgatggacg cggcggccgt gccgcaccgc
     9781 cgccaggtct tgactccagt catgtgctgg tcctcctctg tgtggggcag agaacggtgc
     9841 tcgcgcgcac tggcgggggc accgcgcatg gccaggtgac ggagctcagt gtcgtccccc
     9901 gaccccacaa gcacgccatg gacattcgcg gtccgggctt ggactatccc gcgcggcgcg
     9961 cccgcaccgc gtcagcggag cacggcacgg cggcagcggc tcagcacagc aacagagcgg
    10021 cctgccaggg cagttcaccg agcggcgcct ccgggtgcgt cgcgtggcgc agggcgagcg
    10081 cggcgcccac cgctccgtcc aggaagccgg gccggtgcac gaccgtgcgc tcgccgggtg
    10141 cggcggcggg ccacaggaag gggtaccccg ggtccgccgc ggccgccagc gcgtcggtca
    10201 acctcggtac gagagcggcc agttcgtctc ccccgggctc cttggacatg agggtcacga
    10261 tcgtggtgag ccccgccagg ccgtggcaga gcgtggggtc ggggaagtcc ctgcggtcgc
    10321 aggcggcggc gaccgcggcc acggcctgcc ggttccactc cggctccttg agtgccagcg
    10381 cggccagttg gagggagcgg gcgacgccgg gcgtgccgta gcaccagccg gtgcgcgcct
    10441 ccgccaggtc ggggcgggcg ccggaagccg ccgtcagctc ggcgcccagc ggcacgatgt
    10501 tgggccaccc cgcaccgtcc gggctgcggc gcgcgaggag ccagtcggcg atggtgcgga
    10561 tcgcccgctc ctgccccggc acgcggacgc ccgcgcggtg ggcgagggag agcagcgcga
    10621 gcggcccggg gatgccgtgg gcgagacccg cgttgaagtg tccaccgggg actccctcgg
    10681 gctcgctgag caggatcggg tcgctggtcc accagccggg cacggtcctg ccgcccggtt
    10741 ccacgaccgg gcgggtgagc gcgacgaggt gaccgaggac gagctcggtg gtgtcccggt
    10801 ggtcgggtcc ggccgcgagg agcagccgcc ccagaccggt gaggcccgcc accacgtcgt
    10861 acccggccat ccgggccccg gccgtccctg ccgccacccg cggggcgtcc tccgccacga
    10921 tcctgcgggc gagcagggcg acttggtcgt ccagcttggt gagcagcccg gcgtactcac
    10981 cgggccgggt gacggccgtg cgggcggcga aggcgaccgc gggcaggccc gcgtacagcc
    11041 cttcgcgcgc gggcctgcgc accccggtga cggcgctcgt caggtgggcg tgcgcggctc
    11101 gcgcgtaccc ggcgtcggtg tgggcgagcg ccccgagcag cagggcgacg cccgcgtggc
    11161 cgtccgcgag ggactggggg tgccacaggg accgggtctc ggccagttcg ggggtctgcg
    11221 cctcggtcac ctgtgcggcc agggcgaccg gatcggtgag gcgctcggcg agcagcgcca
    11281 cggggttctc ggtcatgatc cggccctttc ccggtcgagg tgtgcctgga ccgcgccccg
    11341 ggccacggcc agggcctgcg cctcggccgt acggtcggtg ccgaggcgcc ggttgcagtg
    11401 catgtggacg agggaggcga gcaccgcgtc cggggagacg ctcagtgtgc cgcgccgctg
    11461 ttcctcgcgc atcaggtgcc cgaagcgctc gggcgccgcg tggtgcgcgt gggcctcggg
    11521 accgtccggc gtgatgcgcg cgagggcttc gcgccgtcgg gccgcgaacg ccttgtggtg
    11581 cttctcccgc ttggggtacg tggtggtgat ccactgccgc cagtccccgc cgtagccccg
    11641 gtggaaggcg cggacgagcc cggccacgtc gtacgcggtg gacaggatcc ggtcgtccgt
    11701 cggggtcgcg agccgctcga tcaccagtcg gctgtccgcg tggaacacct cttcggccgc
    11761 gccgagcacg accgggccgc cgtagcgctc ggtctcgggg gcgtagctgt cgaggcgcag
    11821 ccctcgggcg agcccgtcgg cggccagttc cccggccagg tcgtggagtc cgggcagcac
    11881 gacgccgttg agcagggccg ggtcgccgtg cagccggagg cgcaggtgcg ggtccgggtc
    11941 ggcgtaccgg atgaagaacc accggtcgac gccgcccggt tcgtcctgcg gggcgggcag
    12001 ctcggtcagg aagcgccgca acggcccggt caggagttcg tcctgacgct cggcggaggt
    12061 gtagagcgtc gcgtagagcc aggggccgcc gggcgggatc tcgccggtgc cgcgtcggct
    12121 cgcggggagc gcgatgcgcg cgggcttcgc gggcctcggt tcggcgttcc gctgacgggg
    12181 cgtcagcgtc acgacggctt ccgcttcgtg ggcgccgccg ggcccgtgca gccaaccgct
    12241 gtcggggtcc tggcccagcg gcggctcgtg caccacggcc gcgccggtcc gctcgcactc
    12301 gcggcgcagg atctcctggt gcgcgggaac ggagaggttc agggggatgc ggtggtcgcc
    12361 gagggtgagc tggacgtggt ccggcacgtg ccagagcgcg cgccactccg ccagggacgg
    12421 gcccgtcgcc tccaggcgcc agcgggccgg ggccaggacg gtgcggccga cgcgtacggc
    12481 gggcaggaac ggcaggtcct ccgcggcgcc ccattcccac agccgccact gcctgcggct
    12541 gaacgcggcg gcctcgatga ggaagcgcac cgcgttgggc gcggtcagtt cgcggttgag
    12601 cacgtgcagc gccgaggggg tcagctcgcg gccgagtgcg agcgacacga tccggaagcc
    12661 ctcggagtcg gcgcagacgg cgatgtcgtc gagcgtgagg tcggtgacgc ccggcgccgc
    12721 gggaccggga tgcacgccga tgaccaggcg tccgtccagc caggtgggca cctgcgcgac
    12781 attggcgtgc cggtggtgcg aggcctggtg gtggacctgg acggggaggc gcccggtgtc
    12841 ctcgcgcgcg tcccgcaccg tgtgccggat cgcctcggcc tgcgcgggct cgaagaggtg
    12901 ggcgaacctg cccatgaggc cgccggacgc ggtggccgcg ccgttgagga cgagcgtgta
    12961 gtcgcccctg tccaccgcgt cggccgatgt cgccgcgatc tgcacgacga gttcgagggc
    13021 gggcggtcgc acggcgggcg cgtcccggtc ggcggactcg gcgcggtcgg cggactccag
    13081 cttgcgcagc cactgctcgt ccaggacgac ctcgcgcgac ccgcgcgcct gcgcctcggc
    13141 cgcgagaccc agcagcagcc gctggcgtac ggcgcccagg ggcgcgggcc ccgggtcgga
    13201 gcggtggctg ggcggcagcc ggtatccggc aggggcaccg agaccgatgt cgggatcgag
    13261 gagttccttg acggggacgt agcgcccgag gccgtaccgc tcgacgaagt cctggtggta
    13321 ggcggtcaac cggcccctgc cctggggcgc gaggcgccac agcgcggcgg cggcgtgctc
    13381 cagttcgcgg gccacctcgt gcgagagcac gacggagccg tccaggcgca ggtccacctg
    13441 gacggcgtgc ccgctcgccg gggcgtcctc ggtggcacct gtggcggctc ccagtgccgt
    13501 gcgccaggcg gcccttccct cgccgagcgg ggtacggagg tagtcggtga gggacgtgcg
    13561 cagctcggcg atgcgtcggg cggcgggggt gtcggccggg agcagcgcct cgacgtgtgc
    13621 cagcgggtcg ggggcgtcca gcggcggacg cagttccgtc aggagcactt ccgcgccgat
    13681 gagctgggcg acgagccggg cgaccgcgcc ctcgggagcc ccggggaaac gtgcttcgac
    13741 gtcgcggacc agttcgtcgc agcggacggg gcgggcggcg gcctcgagaa cggcgcgtac
    13801 gaccggggtg tggcgcagcg tacgtgactt ggggcggctc gcgtccgacg aggcggtgtc
    13861 cgggccgggt ccggcgggcg cgaagggcag gaccaggcgc ccgccgcgta cgaagcacag
    13921 tccgttgacc accacgctca gtccctggtg cacggcgggg tcgcgctccc actcggcgac
    13981 cagccgggcc agcagaccgg cgtcgagccg tgccgccttg tgtccctcgc cggtgagttc
    14041 gcccttggtc gccgcgccga aggagcccca caggacgccc gcgagcagac cgaagggggt
    14101 gggcctcgac gcggccctga gcagatagcg ggtcaccgcc cggtgggcct tgcgcagatc
    14161 ggccggggtt accggcgcgt tcgcgaggac ggcgtcgacg gtgcgggcga gcgaggggct
    14221 ggagacctcc accgcctcgc gaaagcgggc gtcggcgagc agctcttcga gttgggcccg
    14281 tcggccttcg aggtccgtgg aatccggcga ctccgcgccg gtcccgtcct ggctctcccg
    14341 cacgccgtcc tgccaggtcg cgcgagctct cggccgtgcc aggagcggcg ccctcaaaag
    14401 cactccgtcc gcgcagtgga acaccgtttc cgcgctttgg acctgccgca tctgcgccac
    14461 tcccccttac tccatgcccc ataaaaagaa gttaagaatc cccaattccc tacccgagga
    14521 atgcggtcac actaacccag gcgcacttca cccgtcaccc cttgactccg tccgctatcc
    14581 gtacctagat tccgttctcg tcgccaaagg gcggcgattc gttcggtttc aaaggttcca
    14641 tggaaggaat tcccatgccc gagagcatga cgcaggacct cttcgacatc gacctcaccg
    14701 agacctccat ccaggacgtc gcgcaggaca gcgccgcggg cgcgatctcc ggcgaagagt
    14761 cctgcttccg cacgtgtacg acctgctcgc tctgctgacg caggccatgt gaagggccgg
    14821 ttccggcgac gcctcgcatg gccggaaccg gcccggtcgc acccgtttca cgggcgcgag
    14881 aacactgaag ggcaatgcgc attgcccttc agggcacaca ccgtcgacct gctgggcagg
    14941 gtttccgtgc tctgcacttc accgttgaca cagcgaggga ttatcggcga ccttttcttt
    15001 cgtgacgcac ttttccgcgg gcggccgaga acgcatttcg cgcccgtata taaacatgcg
    15061 tacgggtaat ttctgagccc gctacgcaga ggaccgctag gcgcggaaca cctggcgaag
    15121 gagttcgccg aactcgtcgg ggtgggtggt caggccggtg tgcccgccgg ggaagtgacg
    15181 gagttccgtg ccgcatcgct cggccaggaa ggccgccggg cggtagggca gttcaccgtg
    15241 ggagtcctgt ccaccggcga acacgacgcg gtccgcgagt tcttgcaggc gggcgacgtc
    15301 cggggcgtag gccatgaagc tggggatcac gcgtccgaag aagtacggca ggttcgccat
    15361 cgtccgctcg gcccgtgccg ccgcctgggg cggaagcgtc aactcgggct tcggcgcggc
    15421 gggtgcgccc tttccggcgt cgtcgttccc ggcatccccc ttcctcttcg ccccctcggc
    15481 gaacacggac accgcgggca tgagcccttg cgtgcggaac gtctcctgca cgcgcgcgag
    15541 gagcgcgcgg tgttcggcgg cgtccggcag gacctccacc acgggcggct catgcgccac
    15601 gagacgctcg acgcgttcgg ggtgcgtggt gagcaggtgc agggccgcga tcgcgcccga
    15661 gctcataccg aacaccctgg cgggttcgcc gggcgagagc agttccagga gccggaaggc
    15721 gtcgtcggcg tgttcggcca cccgctgcgc ggcctcgggg tcgtcgagcg cgctccggga
    15781 aatgccacgc gggtcgtagg tggcgacggt gtactcggcg gccagaccgt cggcgaggtc
    15841 gtcgaaggcg gccgcgccgc ccgccccacc gggtatcagc agcaggagcg gcccttcgcc
    15901 gcgcacttcg tagtgcaggg tcgcgcccgg cacgcggagg gtgccggtgg tcggggcggc
    15961 cgaggccgta ccagtcgggg gcgtggtcgg cgtggtcggc gtggtcggcg tggtcggcgt
    16021 ggtcggcgtg gtcggcgtgg tcggcgtggt catgcggatt ctccgtctcc gagcgggggc
    16081 cagtgctcca gaagggcgtg cagggcgtcg agggcgcgga cccaggactg ctgcggcgcg
    16141 cgctggtgcg cgaagccgcc catggcttcc agggcgacga acccgtggaa agtgctgcgc
    16201 agcagccgta ccgcgtcggt caggtcgggc tcggcgaggc cgtagccgcg cagcatgccg
    16261 taggtcagct cgaccgcgcg gcgcggcccc ggcgcgtgcg cggccagttc ggggtcgatg
    16321 tcgatcgggg tctgcgtcgc cgtgtagcgg cccgggtgct cgtgggcgta ctcccgccag
    16381 gcggtggcga acgcgaccag cgcgtccttg cccgcgaggc cgaccgtcgc ctcggcaatg
    16441 cggatggtct tctcgtccgc cgcgaggagc gcgatccgtc ctcgcaggtc caccaggttc
    16501 cgtacgtgcg tgtagagact cgcgtccttc acgccgagcc gccgcgccac ccgcgacatc
    16561 gtcacctgct cgaacccgac ctcgtccgcg agctcggcgc ccgcgaccgt cactcgctcc
    16621 gccgtcagcc cggcccgcac catgtgcact ccctgcaagc ttgccctcct aggcgtttcc
    16681 taggacccct aggatgcact ttgaggtcct aggaacgcaa cagagaaggg atctccgcag
    16741 agcgctaccg cgctggttga cgcggcagcc gggccctcag cccgtacagg acaccgggac
    16801 gcgggcctga tctttgtggc ttcagccagt acgtcccctc gtcgaggggc gggaagactg
    16861 cgcgccagga cacggccacg caccagggga gaacagcacg atgagcgcgc agcagtacga
    16921 cgagatcggt gaggcgtacg aggggttcaa ggctctgccg ctggagcagt actcggtggt
    16981 gcccgggttc ctggcgctgg tcggcgacgt gcgtggcaag tcggtcctcg atctggcctg
    17041 tggcaccggt ttctacagca gggagttcaa gcggcgcggc gccacggagc tgctcgggat
    17101 cgacatctcc ggcgaaatgg tcgccgtggc acaggcgttg gaggagcgcg acccgctggg
    17161 cgtgcgctac gaggtgggcg acgcgtccga actccgcgcg ttcgacgagc ggttcgacgt
    17221 cggcctggcg gtgcagctgc tcaactacgc cgaggacatc gccaccacgg agcggatgtg
    17281 ccgcaacgtg caccgcagcc tcaagcccgg cggcgagttc ttcctgctca accagtcacc
    17341 cgacttcgat ttcgacgggc cgacgccgga gaagtacggg ttccgcagcg tgctcaccgg
    17401 cgagcaggtc gagaccgggc cgaaggtgcg gaccaccgcc ctgctcgacc cgcccgtctc
    17461 gttcgtcgcc aacctcccgc gccgcgaggt ctacgagacg tgcctgcggg ccgccgggtt
    17521 cagcgagttg acctgggtcc ccctgacggt gtcggaggcc ggggtgcgcg agttcggcgc
    17581 ggatcactgg gcggactacc acgccaatcc cccgctggag atgctgcgtt gccgtgtctg
    17641 atcaccgccg ggctgggcgt cccggcccgt cactggcggc gggcgttgag ccgggccgcc
    17701 tggcgtgtca ggtggtcgcg ctcggcgagg ttggctgcct tcccggccgc atcggcgtac
    17761 agccgcgccg ccgtccccag gtctccgtcg cgctcgtgga ggtaggccgc caccgccgtg
    17821 tgacggggca gcgtgtcgtc cagctccgcg agctccgcca gacccgcgcg cgctccgtcg
    17881 gcctcgccca cggccaccgc gcggttgaga cggacgaccg ggctgccggt cagacgtacg
    17941 agctcgtcgt accactccac gatctgcacc cagtcggtct cctcggccct ctgcgcgtcg
    18001 gcgtgcaggg cggcgatggc ggcctgggcc tggaactccc ccagccggtc gcgggcgagg
    18061 gccgtctgca ggatgccgat gccctcggtg atcagttcgg tgtcccagcg gccccggtcc
    18121 tgctcggcga gcggcaccag ggcactgtcg ggccctgtcc tggccgcgcg ccgggcgtgg
    18181 tgcagcagca tgagggcgag cagccccacc acctccgggt ggtcgatgac ggccgcgagc
    18241 tggcgggtga ggcggatggc ctcggcggtc aggtcgacat cggcgtcggt cgagtacccc
    18301 tcgttgaaga ccaggtagag gacgcgcagc acggtggcga cgtcgccgtg ccggtcgagg
    18361 cgcacgccgg acacggtgcg tttggcgcgg ctgatgcgct gcgccatggt cgcctcgggg
    18421 accaggtagg cgcgggcgat ctggcgggtg gtcagcccgc cgacggcgcg cagggtgagc
    18481 gccacggcgg acgacggggt cagggacggg tgggcgcaca ggaagtacag ctggagggtg
    18541 tcgtccaccg cgggtgcggg gcccggggcc ggttcctcct cgatgaggtc ctcccgccga
    18601 cggcgggcgg tgtccgcccg ccgcgcgtcc aggaagcggc gccacgccac cgtgaccagc
    18661 cagcccttcg ggtcgcgcgg cgggtcggcg ggccagacgc gcaccgcctc caccagcgcg
    18721 tcctgcaccg cgtcctcggc cgccgcgaag tcggctccgc ggcggacgag gacggcgagc
    18781 acgctcgggg tgaggctccg gagcagggtc tcgttcatcg aggaggtcac cgaggaggtc
    18841 actcggtgat ggtgggcttc gcgcccatga acgggcgtac ttccagccac tcgtggatcg
    18901 gcttgccgcc cgcgccgggc gcggccgaca gctccccggc gagctcgacg gcccgctcct
    18961 ggctgtcgac gtcgatgatc atccagcccg cgatgaggtc cttcgtctcg gcgaaggggc
    19021 cgtcggtgac cggcgggcgg ccttcgccgt cgtagcggac gaaggatccc ccgggggcga
    19081 gcgcctggct gtcgacgaac tcgccagtct ccttgagccg gtccgcgaag tcgttcatgt
    19141 accgcatgtg gtccgagacc tcctcgggcg tccactggtc catggggacg tcgttgaccg
    19201 atgccggggc gcctcggtag tgcttgagca gcaggtactt ggccatggtg gctctccttg
    19261 gtgctggtgc ggcccattgt ggtcgcgttc gtaccgggga cggagccgat cacgggttct
    19321 cgacatcggc gaccggattt ttctgccgac tttcgctacc ccttgcgtga cttcatgtac
    19381 caggcggcgg cgatgccgat gaggacgagg atgatgagga tcttcatggt cttcacctcc
    19441 ccccgatcgt gagggacatg ccgatcgtga gggacgtgcc gatcgcgcgg gacatggctg
    19501 ggccgacggg tcagcggccc ggcggctgcc actcgatcat gaggatggtc gcgtcgtccc
    19561 tgagcgactg ggactgcgtg tccaggaccg agtggatgag cctgcgcagg gtctcgggcg
    19621 ccacttcccc ggcggtcgag gcacggatca ccgagtcggc gaaccgttcg aggccgaatt
    19681 ccgtgccgtc ggctagccgc gcctcggtca gtccgtcggt gtagaggagc acgcggtcgc
    19741 cgggttccag cgccgtctcg tgcacttggc gctccgcgct gcggaacgac gcggagaagc
    19801 ccatgggcga gtcgggttca cgttccaggg ccccctcgac gagccggttg ccgcggatca
    19861 gcaggggtgc cgggtgtccg cagttgctcc agcgcagggc cccgctcgcg aggtcgagcc
    19921 ggagcaggac gcccgtgcag aactggtcgg gcagccattg gccgagcgcc gcgtccacgg
    19981 cctccatgag ctccggcagg tccgacccgg tgcgtcggcc gttgcggcag gcggcgagag
    20041 ccaccgccgt ggtgagcccg gagagcaggt tgtggcccat ggcgtcgacg atcgtggcgt
    20101 gcagggccgt ccgggtgagg cagtgatcga aggcatcacc cccgatctcg tacgcgggtt
    20161 cgagcactgc ggtcgagatc acgtggtggt tgccgatggt gcgcggcggc aggaaggcgc
    20221 ggagcatctc ggcggggagc cgcatgggtt cggcgcgggt gcactggacg acgttgtcct
    20281 tgtaggcgcg cttcgaggtg atcatcatcg cggccagcgc tgccagggcc cggccgcgcc
    20341 gcagcagggc ggcgtccagg tacggcgcgt ggacggcgag cacgcccagc cgctcggccc
    20401 cgtccagaag gggcagccag gcggtcatgc caccggtcgc ggactccccc gcgcgcaggg
    20461 acaacgtgcg gtaggcccag cccgcggccg agccgtccac cgcgacggcc gccgccgatt
    20521 cgtccagggg gaccaggagg cgctgctgga ggtcgacgag gtagaccgtc gcctcgggca
    20581 cgcccagggc gctcgcgcag cgggccaccg cggtggagag gtccagtacg gcgttgtcgc
    20641 ggtccgcgag gaaatccacg agtccgctcg gcgggtccga tgtcgacacg tcgtctccct
    20701 ccacctgcgg cagcaggagc agtctcacac ccccgtgccc gatccgcccg tgcccgtgtc
    20761 gcagatcccg cgcgactggt ccacggtgat cagtacgagt tgtcccgccg cgtgcgggta
    20821 cctgcacccc agccccggac ggaccggcgc ggcagagagg agccatcgtg agtgaacagg
    20881 taccggcgtc ccccggcgcg gacggcagca cgcccgtacc cagggacctg cccgatcagc
    20941 aggcggacgg cggacaggac ccctgggagc tggccgagga cggcaaggac gccaagagcg
    21001 gcaggaccgg cgcggccgag gacggcgatg gcggggccgc ggacgacgtg cccgacaccg
    21061 acgaggcagg caccggtcgg cgcggtgaat ccggaggcga ccagggcgga cgggacgcgg
    21121 aggacgggca cgatgcgagc gccccgaccg acaacccgga gcccgaggag ccttccggat
    21181 gaggcgaagc gggacgacac gagacaacgc gagggaaagg gaacggccgt gagtggtacg
    21241 ggagatgccc cggcgcaggt gtcggtggaa ctgagcggtg gcgcggacga cgccgggagc
    21301 gtgttcgccc tgctgggggc ggctttcgcc tcggaccggg ccgatggtcc cgcgccgcgg
    21361 gcggcggagt ccggtggacc gaccgtgtgg agcggcgtct tcgacaccgc gcgtcccgcg
    21421 ggcggcgggc cgagcgggtc accgtccctg agcggcccgg tgaccgccag cgtgcaaggc
    21481 ggctacgtgg cggtcgaccg ggtcgtcacg gtgctctcgg cggcgttcac cgtcaccgag
    21541 gagggctccg cttcgggcga ccaggagaag gacgtgaacc tgcggctgga aggcgcgtga
    21601 cgctgccccg ggggcccggc cggggcgtcc cgcccggccg gggcgtccca gccgggccgc
    21661 ctggagcggg cttctcaccc ccgttgccca cccggaatgc gctccagcag accgcgcagg
    21721 tcgtcggcgt gctcctcctc ctgtgcgagg agttcctcga agacgcggcg cgtggtgggg
    21781 tcgccgtccc ccagccactt ggcgatctcg gtgtaggcgg ccacggcgac gcgctcggcc
    21841 accaggtcct ccttgatcat ctcgatcagg tcggtgctgg cgtcgtactc cgcgtgggcc
    21901 cgtgacgtga gggtgtcggg gttgaagtcg ggctcgccgc ccagctgcac gatccgctgc
    21961 gccagcttgt cggcgtgctc ctgctcctcc tgcgcgtgtt ccaggaactc cgcggccacc
    22021 ggctcggagt agagcccgga ggcggtgtag tagtgccgct tgtagcgcag cgtgcagacg
    22081 atctccgtgg caagggcctc gttgagtacg ccgagaacgc gctccaggtc cgccccgtag
    22141 gcgtccgtca ccggaccctt ctcgatctgc tggcgggccc gctcgcggat ggtcttgatg
    22201 tcggtcagga actcggccat gacaactgat ccctccttgg tgaacgacgt gcggtggcgg
    22261 accgtcctgc gggccgccac cgtggaccgt acccatttct ccgcatttat cccgaaggcg
    22321 cctcacaagg cgtttcatcc cgcgtgccac cccacgcgcc gggtgcacat cgcgtaacca
    22381 ccgaccgacc cgcccaaaca gggtcatggc gtgttctcgc tgtcacccgc ggtagtcacg
    22441 gtgttcggat atcggacacc gctctcacca tgcgggcaag aaatccagac ttgcccgcat
    22501 gccttcctcg acaagcacac ctcccaagcc cgcgctcacc ccggagccac agctcgccaa
    22561 ggggctcaag cagcggcact tgtcgatgat cgcgctcggc ggagtcatcg gcgccgggct
    22621 cttcgtgggg tccggagcgg gcatcgccgc cgcgggaccc tcgatcgtcc tcgcctacac
    22681 cgcttccggc ctgctcgtca tgctggtgat gcggatgctc ggcgagatgt cggccgccca
    22741 tccggcctcc ggctccttct ccgtgcacgc cgaacgcgcg atcggaccgt gggcgggctt
    22801 cacctcgggc tggtcgttct ggttcatgct gtgcatgggc gtgggcctgg agggcatcgg
    22861 cgccgcccac atcatgaccg gctggctgcc cggcacgccc gagtgggcgt gggtggcgct
    22921 gttcatggcg gtgttctgcg gcgcgaacct ggcggcggtg aagaacttcg gcgagttcga
    22981 gttctggttc gccgcgctga aggtcggcgc gatcgtcctc ttcctcgccg tcggcggact
    23041 cgccatcgcc ggggtgctgc ccggcacgga cgcgcccggc accgccaacc tcgtcgggca
    23101 cgggggcttc ctgcccaacg gcaccgaggg gctgatcatc ggcttgctcg cctcggtcct
    23161 cgcgtacggc ggcctggaga ccgtgaccat cgccgccgcc gagtcggacg acccggtgcg
    23221 cggcgtcgcc ggggccgtgc gcacggcgat gtggcggatc gcggtcttct acatcggctc
    23281 gatgctggtg atcgtggcgc tggtgccgtg ggacgacaag gaggtcgtgg agaagggccc
    23341 ctacgtcgcc gctctcgacc agctggggat ccccggtgcg ggccagatca tgaacgtagt
    23401 cgtcctgatc gcactcctgt cggcgatgaa cgccaacatc tacggctcct cgcgcatggc
    23461 ctgttcgctg gtctcccgcg gccaggggcc cgccgcgctc ggccgcaccg tctccggagt
    23521 gccgcgccgc tcggtcatcg cctcgtccgc cttcggcttc ctctgcgtcc tgctgagcta
    23581 ctggcggccc gacgacatct tccagtggct gctgaacatg atcggcgcgg tgatcctcgt
    23641 cgtctggacg ttcaccgccg tctcccagct gatcctgcgc cgccgcaccg aacaggagga
    23701 gcccgggaag ctcgcggtgc ggatgtgggc gtatccgtat ctgacctggg tggcgctggc
    23761 gggcatggcg gccgtgttcg tcctgatggc gctggagccg accacccggg ggcagctcgc
    23821 gtggacgagc ggcctcaccc tcgcgctcgt gatcgccgga tacgtacggc agcgaacggc
    23881 ccgcggacgt cgttgagccg cgcttcgtgc ccccgccggg aggtcccggc gggggcgcgg
    23941 tgctaggcgg gcaccaccgc gaccgggcac tgggcgtgca gcaggaccgc gttggcggcc
    24001 gagccgacga ggaacgagtc ggcgttcacg cggcgccggt gacggccgac gaccagcagg
    24061 tcggcggtct gcgaggccac gacgagacgg cccgcggcgt cggccgcggt gaccaccttc
    24121 tcgacggcca catcggggta gcgctcgatg aaggcgccga gccgttcgtc ctgcgcctcc
    24181 gacaacgcct tctcctcgcg cgggctctcg ggcgtccccg ccgcgtccag gtatccgccc
    24241 atgagcgcca aggtcgagaa cggcaccggg tacgtggtga tcacctggag cccggcgccc
    24301 ctgcgcccgg cctcctcgaa cgcgaactcc accgtggcat cgctcgtctc ctccggcgcg
    24361 aggccgagcg cgaccctgcc gaacgtgccc gccgcctcga ccgactcggt cctcgcggca
    24421 tgcgggacga cgaccacggg acaggcggcg c
//
